The purpose of the cross border TTX was to assess and further enhance the level of outbreak preparedness in the East African region in particular focusing on the one health approach. National emergency preparedness and response plans, the regional contingency plan, the regional risk and crisis communication strategy (draft) were validated. Standard Operating Procedures were also examined. The TTX familiarized participants on their roles and responsibilities including risk and crisis communication, multiple stakeholder coordination, logistics, administrative processes, management and leadership as well as financing a response.