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A curcumin-loaded liquid crystal precursor mucoadhesive system for the treatment of vaginal candidiasis 2015 School of Pharmaceutical Sciences, UNESP - Sao Paulo State University, Campus Araraquara, Department of Drugs and Medicines, Araraquara, Sao Paulo, Brazil.; School of Pharmaceutical Sciences, UNESP - Sao Paulo State University, Campus Araraquara, Departme
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of nanomedicine
Periodical, Abbrev.
Int.J.Nanomedicine
Pub Date Free Form
30-Jul
Volume
10
Issue
Start Page
4815
Other Pages
4824
Notes
LR: 20150812; JID: 101263847; 0 (Drug Carriers); IT942ZTH98 (Curcumin); OID: NLM: PMC4525803; OTO: NOTNLM; 2015 [ecollection]; 2015/07/30 [epublish]; epublish
Place of Publication
New Zealand
ISSN/ISBN
1178-2013; 1176-9114
Accession Number
PMID: 26257519
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.2147/IJN.S82385 [doi]
Output Language
Unknown(0)
PMID
26257519
Abstract
Women often develop vaginal infections that are caused primarily by organisms of the genus Candida. The current treatments of vaginal candidiasis usually involve azole-based antifungals, though fungal resistance to these compounds has become prevalent. Therefore, much attention has been given to molecules with antifungal properties from natural sources, such as curcumin (CUR). However, CUR has poor solubility in aqueous solvents and poor oral bioavailability. This study attempted to overcome this problem by developing, characterizing, and evaluating the in vitro antifungal action of a CUR-loaded liquid crystal precursor mucoadhesive system (LCPM) for vaginal administration. A low-viscosity LCPM (F) consisting of 40% wt/wt polyoxpropylene-(5)-polyoxyethylene-(20)-cetyl alcohol, 50% wt/wt oleic acid, and 10% wt/wt chitosan dispersion at 0.5% with the addition of 16% poloxamer 407 was developed to take advantage of the lyotropic phase behavior of this formulation. Notably, F could transform into liquid crystal systems when diluted with artificial vaginal mucus at ratios of 1:3 and 1:1 (wt/wt), resulting in the formation of F30 and F100, respectively. Polarized light microscopy and rheological studies revealed that F behaved like an isotropic formulation, whereas F30 and F100 behaved like an anisotropic liquid crystalline system (LCS). Moreover, F30 and F100 presented higher mucoadhesion to porcine vaginal mucosa than F. The analysis of the in vitro activity against Candida albicans revealed that CUR-loaded F was more potent against standard and clinical strains compared with a CUR solution. Therefore, the vaginal administration of CUR-loaded LCPMs represents a promising platform for the treatment of vaginal candidiasis.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Salmazi,R., Calixto,G., Bernegossi,J., Ramos,M.A., Bauab,T.M., Chorilli,M.
Original/Translated Title
URL
Date of Electronic
20150730
PMCID
PMC4525803
Editors
Rapid determination of polycyclic aromatic hydrocarbons in grilled meat using microwave-assisted extraction and dispersive liquid-liquid microextraction coupled to gas chromatography-mass spectrometry 2015 Department of Food Science and Technology, Faculty of Nutrition Science, Food Science and Technology/National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Chemistry, Faculty
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Meat Science
Periodical, Abbrev.
Meat Sci.
Pub Date Free Form
May
Volume
103
Issue
Start Page
61
Other Pages
67
Notes
CI: Copyright (c) 2015; JID: 101160862; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); OTO: NOTNLM; 2014/06/18 [received]; 2014/12/09 [revised]; 2015/01/05 [accepted]; 2015/01/08 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1873-4138; 0309-1740
Accession Number
PMID: 25618021
Language
eng
SubFile
Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.meatsci.2015.01.001 [doi]
Output Language
Unknown(0)
PMID
25618021
Abstract
A simple and rapid analytical tech nique for the simultaneous determination of 16 polycyclic aromatic hydrocarbons (PAHs) in grilled meat was developed using microwave-assisted extraction and dispersive liquid-liquid microextraction (MAE-DLLME) followed by gas chromatography-mass spectrometry (GC-MS). The effective parameters in DLLME process were optimized. Good linear relationships were obtained for 16 PAHs in a range of 1-200 ng g(-1), with a correlation coefficient (R(2)) higher than 0.98. Limits of detection and limits of quantification were 0.15-0.3 ng g(-1) and 0.47-1 ng g(-1), respectively. The relative standard deviations (RSD%) for seven analyses were less than 9%. The recoveries of those compounds in grilled meat were obtained from 85% to 104%. Low consumption of the solvent, high recovery, short extraction time, no matrix interference and good merit figures compared to other methods are advantages of the proposed method. The performance of the present method was evaluated for the determination of PAHs in various types of real grilled meat samples, and satisfactory results were obtained.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Kamankesh,M., Mohammadi,A., Hosseini,H., Modarres Tehrani,Z.
Original/Translated Title
URL
Date of Electronic
20150108
PMCID
Editors
Ever Use of Nicotine and Nonnicotine Electronic Cigarettes Among High School Students in Ontario, Canada 2015 Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; hayley.hamilton@camh.ca.; Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Dalla Lana S
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Oct
Volume
17
Issue
10
Start Page
1212
Other Pages
1218
Notes
CI: (c) The Author 2014; JID: 9815751; 6M3C89ZY6R (Nicotine); 2014/04/01 [received]; 2014/10/22 [accepted]; 2014/10/30 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25358662
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/ntr/ntu234 [doi]
Output Language
Unknown(0)
PMID
25358662
Abstract
INTRODUCTION: There are limited data on the use of electronic cigarettes (e-cigarettes) among youth, particularly with regard to the use of nicotine versus nonnicotine products. This study investigates ever use of nicotine and nonnicotine e-cigarettes and examines the demographic and behavioral correlates of e-cigarette use in Ontario, Canada. METHODS: Data for 2,892 high school students were derived from the 2013 Ontario Student Drug Use and Health Survey. This province-wide school-based survey is based on a 2-stage cluster design. Bivariate and multivariate analyses were used to investigate the factors associated with ever use of e-cigarettes. Ever use of e-cigarettes was derived from the question, "Have you ever smoked at least one puff from an electronic cigarette?" All analyses included appropriate adjustments for the complex study design. RESULTS: Fifteen percent of high school students reported using e-cigarettes in their lifetime. Most students who ever used e-cigarettes reported using e-cigarettes without nicotine (72%), but 28% had used e-cigarettes with nicotine. Male, White/Caucasian, and rural students, as well as those with a history of using tobacco cigarettes, were at greater odds of e-cigarette use. Seven percent of students who had never smoked a tobacco cigarette in their lifetime reported using an e-cigarette. Five percent of those who had ever used an e-cigarette had never smoked a tobacco cigarette. CONCLUSION: More students reported ever using e-cigarettes without nicotine than with nicotine in Ontario, Canada. This underscores the need for greater knowledge of the contents of both nicotine and nonnicotine e-cigarettes to better guide public health policies.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Hamilton,H.A., Ferrence,R., Boak,A., Schwartz,R., Mann,R.E., O'Connor,S., Adlaf,E.M.
Original/Translated Title
URL
Date of Electronic
20141030
PMCID
Editors
Implementation of Ebola case-finding using a village chieftaincy taskforce in a remote outbreak - Liberia, 2014 2015
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
27-Feb
Volume
64
Issue
7
Start Page
183
Other Pages
185
Notes
JID: 7802429; ppublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 25719680
Language
eng
SubFile
Journal Article; IM
DOI
mm6407a5 [pii]
Output Language
Unknown(0)
PMID
25719680
Abstract
On October 16, 2014, a woman aged 48 years traveled from Monrovia, Liberia, to the Kayah region of Rivercess County, a remote, resource-poor, and sparsely populated region of Liberia, and died on October 21 with symptoms compatible with Ebola virus disease (Ebola). She was buried in accordance with local tradition, which included grooming, touching, and kissing the body by family and other community members while it was being prepared for burial. During October 24-November 12, eight persons with probable and 13 with confirmed Ebola epidemiologically linked to the deceased woman had onset of symptoms. Nineteen of the 21 persons lived in five nearby villages in Kayah region; two, both with probable cases, lived in neighboring Grand Bassa County (Figure). Four of the confirmed cases in Kayah were linked by time and location, although the source case could not be determined because the patients had more than one exposure.
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Database
Publisher
Data Source
Authors
Hagan,J.E., Smith,W., Pillai,S.K., Yeoman,K., Gupta,S., Neatherlin,J., Slutsker,L., Lindblade,K.A., DeCock,K.M., Kateh,F., Nyenswah,T., Centers for Disease Control and Prevention (CDC)
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Tobacco smoke exposure and impact of smoking legislation on rural and non-rural hospitality venues in North Dakota 2015 Assistant Professor of Nursing Executive Director, Healthy Communities International, North Dakota State University, School of Nursing, Department 2670, PO Box 6050, Fargo, ND, 58108-6050.; University of New Mexico College of Nursing, Albuquerque, NM.; De
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Research in nursing & health
Periodical, Abbrev.
Res.Nurs.Health
Pub Date Free Form
Aug
Volume
38
Issue
4
Start Page
268
Other Pages
277
Notes
CI: (c) 2015; JID: 7806136; 0 (Tobacco Smoke Pollution); OTO: NOTNLM; 2015/04/02 [accepted]; 2015/05/11 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1098-240X; 0160-6891
Accession Number
PMID: 25962373
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM; N
DOI
10.1002/nur.21662 [doi]
Output Language
Unknown(0)
PMID
25962373
Abstract
The purpose of this cross-sectional study in a stratified random sample of 135 bars and restaurants in North Dakota was to describe factors that influenced tobacco smoke pollution levels in the venues; to compare the quantity of tobacco smoke pollution by rurality and by presence of local ordinances; and to assess compliance with state and local laws. In data collection in 2012, we measured the indoor air quality indicator of particulate matter (2.5 microns aerodynamic diameter or smaller), calculated average smoking density and occupant density, and determined compliance with state and local smoking ordinances using observational methods. As rurality increased, tobacco smoke pollution in bars increased. A significant association was found between stringency of local laws and level of tobacco smoke pollution, but the strength of the association varied by venue type. Compliance was significantly lower in venues in communities without local ordinances. Controlling for venue type, 69.2% of smoke-free policy's impact on tobacco smoke pollution levels was mediated by observed smoking. This study advances scientific knowledge on the factors influencing tobacco smoke pollution and informs public health advocates and decision makers on policy needs, especially in rural areas.
Descriptors
Links
Book Title
Database
Publisher
Wiley Periodicals, Inc
Data Source
Authors
Buettner-Schmidt,K., Lobo,M.L., Travers,M.J., Boursaw,B.
Original/Translated Title
URL
Date of Electronic
20150511
PMCID
Editors
The prevalence, correlates and reasons for using electronic cigarettes among New Zealand adults 2015 Health Promotion Agency, P.O. Box 2142, Wellington 6140, New Zealand. Electronic address: j.li@hpa.org.nz.; Health Promotion Agency, P.O. Box 2142, Wellington 6140, New Zealand. Electronic address: r.newcombe@hpa.org.nz.; Health Promotion Agency, P.O. Box
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
Jun
Volume
45
Issue
Start Page
245
Other Pages
251
Notes
CI: Copyright (c) 2015; JID: 7603486; OTO: NOTNLM; 2014/10/23 [received]; 2015/01/21 [revised]; 2015/02/11 [accepted]; 2015/02/20 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1873-6327; 0306-4603
Accession Number
PMID: 25744712
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.addbeh.2015.02.006 [doi]
Output Language
Unknown(0)
PMID
25744712
Abstract
INTRODUCTION: There is strong interest in the use of electronic cigarettes (e-cigarettes) globally. This paper is the first to report population-based data on ever-use and current use of e-cigarettes among New Zealand adults. The paper also extends previous international studies by exploring the reasons for trying e-cigarettes, ever users' recall of brand(s) they have ever tried, and current users' recall of their current brand. METHODS: The Health and Lifestyles Survey (HLS) is a biennial face-to-face in-house survey of New Zealand adults aged 15 years or over. In 2014, 2594 participants completed the survey. RESULTS: Ever-use and current use of e-cigarettes were 13.1% and 0.8% respectively. Tobacco smoking status predicted the use of e-cigarettes, with current smokers reporting the highest rate of use (50% ever-use and 4% current use). Among current smokers who had tried an e-cigarette, curiosity (49%) and desire to quit smoking (37%) were the most common reasons for trying. About half of the ever-users could not name any of the brand(s) they had ever tried, and one-fifth of current users could not name their current brand. CONCLUSIONS: Compared with other countries, New Zealand has a high rate of ever-use. Among current smokers, one in two had tried an e-cigarette. However, progression to regular use appears to be rare. The finding that 18% of current e-cigarette users could not name their current brand highlights the importance of investigating users' knowledge of e-cigarettes in general and assessing the factors that influence brand choice such as advertising, price, and accessibility.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Li,J., Newcombe,R., Walton,D.
Original/Translated Title
URL
Date of Electronic
20150220
PMCID
Editors
Comparison of indoor air quality in smoke-permitted and smoke-free multiunit housing: findings from the Boston Housing Authority 2015 Boston Public Health Commission, Boston, MA; erusso@bphc.org.; Boston University School of Public Health, Boston, MA;; Harvard School of Public Health, Boston, MA;; Mongan Institute for Health Policy, Department of Medicine, Massachusetts General Hospital
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Mar
Volume
17
Issue
3
Start Page
316
Other Pages
322
Notes
LR: 20160519; CI: (c) The Author 2014; GR: 1U58DP002478-01/DP/NCCDPHP CDC HHS/United States; GR: P50 CA148596/CA/NCI NIH HHS/United States; GR: P50-CA148596/CA/NCI NIH HHS/United States; GR: R01-HL112212/HL/NHLBI NIH HHS/United States; JID: 9815751; 0 (Pa
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25156526
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1093/ntr/ntu146 [doi]
Output Language
Unknown(0)
PMID
25156526
Abstract
INTRODUCTION: Secondhand smoke remains a health concern for individuals living in multiunit housing, where smoke has been shown to easily transfer between units. Building-wide smoke-free policies are a logical step for minimizing smoke exposure in these settings. This evaluation sought to determine whether buildings with smoke-free policies have less secondhand smoke than similar buildings without such policies. Furthermore, this study assessed potential secondhand smoke transfer between apartments with and without resident smokers. METHODS: Fine particulate matter (PM2.5), airborne nicotine, and self-reported smoking activity were recorded in 15 households with resident smokers and 17 households where no one smoked in 5 Boston Housing Authority developments. Of these, 4 apartment pairs were adjacent apartments with and without resident smokers. Halls between apartments and outdoor air were also monitored to capture potential smoke transfer and to provide background PM2.5 concentrations. RESULTS: Households within buildings with smoke-free policies showed lower PM2.5 concentrations compared to buildings without these policies (median: 4.8 vs 8.1 microg/m(3)). Although the greatest difference in PM2.5 between smoking-permitted and smoke-free buildings was observed in households with resident smokers (14.3 vs 7.0 microg/m(3)), households without resident smokers also showed a significant difference (5.1 vs 4.0 microg/m(3)). Secondhand smoke transfer to smoke-free apartments was demonstrable with directly adjacent households. CONCLUSION: This evaluation documented instances of secondhand smoke transfer between households as well as lower PM2.5 measurements in buildings with smoke-free policies. Building-wide smoke-free policies can limit secondhand smoke exposure for everyone living in multiunit housing.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Russo,E.T., Hulse,T.E., Adamkiewicz,G., Levy,D.E., Bethune,L., Kane,J., Reid,M., Shah,S.N.
Original/Translated Title
URL
Date of Electronic
20140825
PMCID
PMC4837992
Editors
The role of persistent foramen ovale and other shunts in decompression illness 2015 Dr Wilmshurst was Guest Speaker at the SPUMS Annual Scienti fi c Meeting, Bali, May 2014, Consultant Cardiologist, Royal Stoke University Hospital, Stoke-on-Trent ST4 6QG, UK, E-mail: peter.wilmshurst@tiscali.co.uk, Phone: +44-(0)1782-675982.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Diving and hyperbaric medicine
Periodical, Abbrev.
Diving.Hyperb.Med.
Pub Date Free Form
Jun
Volume
45
Issue
2
Start Page
98
Other Pages
104
Notes
JID: 101282742; OTO: NOTNLM; 2015/03/11 [received]; 2015/04/26 [accepted]; ppublish
Place of Publication
Australia
ISSN/ISBN
1833-3516; 1833-3516
Accession Number
PMID: 26165532
Language
eng
SubFile
Journal Article; Review; IM
DOI
Output Language
Unknown(0)
PMID
26165532
Abstract
A persistent foramen ovale (PFO) and other types of right-to-left shunts are associated with neurological, cutaneous and cardiovascular decompression illness (DCI). A right-to-left shunt is particularly likely to be implicated in causation when these types of DCI occur after dives that are not provocative. It is believed that venous nitrogen bubbles that form after decompression pass through the shunt to circumvent the lung fi lter and invade systemic tissues supersaturated with nitrogen (or other inert gas) and as a result there is peripheral ampli fi cation of bubble emboli in those tissues. Approximately a quarter of the population have a PFO, but only a small proportion of the population with the largest right-to-left shunts are at high risk of shunt-mediated DCI. The increased risk of DCI in people with migraine with aura is because migraine with aura is also associated with right-to-left shunts and this increased risk of DCI appears to be con fi ned to those with a large PFO or other large shunt. Various ultrasound techniques can be used to detect and assess the size of right-to-left shunts by imaging the appearance of bubble contrast in the systemic circulation after intravenous injection. In divers with a history of shunt-mediated DCI, methods to reduce the risk of recurrence include cessation of diving, modi fi cation of future dives to prevent venous bubble liberation and transcatheter closure of a PFO.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Wilmshurst,P.T.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Progression to Traditional Cigarette Smoking After Electronic Cigarette Use Among US Adolescents and Young Adults 2015 Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania2Center for Research on Media, Technology, and Health, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvani
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
JAMA pediatrics
Periodical, Abbrev.
JAMA Pediatr.
Pub Date Free Form
Nov
Volume
169
Issue
11
Start Page
1018
Other Pages
1023
Notes
LR: 20160322; GR: KL2-TR001088/TR/NCATS NIH HHS/United States; GR: R01 CA077026/CA/NCI NIH HHS/United States; GR: R01 CA140150/CA/NCI NIH HHS/United States; GR: R01-CA077026/CA/NCI NIH HHS/United States; GR: R01-CA140150/CA/NCI NIH HHS/United States; GR:
Place of Publication
United States
ISSN/ISBN
2168-6211; 2168-6203
Accession Number
PMID: 26348249
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; AIM; IM
DOI
10.1001/jamapediatrics.2015.1742 [doi]
Output Language
Unknown(0)
PMID
26348249
Abstract
IMPORTANCE: Electronic cigarettes (e-cigarettes) may help smokers reduce the use of traditional combustible cigarettes. However, adolescents and young adults who have never smoked traditional cigarettes are now using e-cigarettes, and these individuals may be at risk for subsequent progression to traditional cigarette smoking. OBJECTIVE: To determine whether baseline use of e-cigarettes among nonsmoking and nonsusceptible adolescents and young adults is associated with subsequent progression along an established trajectory to traditional cigarette smoking. DESIGN, SETTING, AND PARTICIPANTS: In this longitudinal cohort study, a national US sample of 694 participants aged 16 to 26 years who were never cigarette smokers and were attitudinally nonsusceptible to smoking cigarettes completed baseline surveys from October 1, 2012, to May 1, 2014, regarding smoking in 2012-2013. They were reassessed 1 year later. Analysis was conducted from July 1, 2014, to March 1, 2015. Multinomial logistic regression was used to assess the independent association between baseline e-cigarette use and cigarette smoking, controlling for sex, age, race/ethnicity, maternal educational level, sensation-seeking tendency, parental cigarette smoking, and cigarette smoking among friends. Sensitivity analyses were performed, with varying approaches to missing data and recanting. EXPOSURES: Use of e-cigarettes at baseline. MAIN OUTCOMES AND MEASURES: Progression to cigarette smoking, defined using 3 specific states along a trajectory: nonsusceptible nonsmokers, susceptible nonsmokers, and smokers. Individuals who could not rule out smoking in the future were defined as susceptible. RESULTS: Among the 694 respondents, 374 (53.9%) were female and 531 (76.5%) were non-Hispanic white. At baseline, 16 participants (2.3%) used e-cigarettes. Over the 1-year follow-up, 11 of 16 e-cigarette users and 128 of 678 of those who had not used e-cigarettes (18.9%) progressed toward cigarette smoking. In the primary fully adjusted models, baseline e-cigarette use was independently associated with progression to smoking (adjusted odds ratio [AOR], 8.3; 95% CI, 1.2-58.6) and to susceptibility among nonsmokers (AOR, 8.5; 95% CI, 1.3-57.2). Sensitivity analyses showed consistent results in the level of significance and slightly larger magnitude of AORs. CONCLUSIONS AND RELEVANCE: In this national sample of US adolescents and young adults, use of e-cigarettes at baseline was associated with progression to traditional cigarette smoking. These findings support regulations to limit sales and decrease the appeal of e-cigarettes to adolescents and young adults.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Primack,B.A., Soneji,S., Stoolmiller,M., Fine,M.J., Sargent,J.D.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4800740
Editors
Motivation to Quit and Interest in Cessation Treatment Among Homeless Youth Smokers 2015 RAND Health, Santa Monica, CA; jtucker@rand.org.; RAND Health, Pittsburgh, PA.; RAND Health, Santa Monica, CA;; RAND Health, Santa Monica, CA;; RAND Health, Pittsburgh, PA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Aug
Volume
17
Issue
8
Start Page
990
Other Pages
995
Notes
CI: (c) The Author 2015; JID: 9815751; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 26180224
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/ntr/ntu261 [doi]
Output Language
Unknown(0)
PMID
26180224
Abstract
INTRODUCTION: Approximately 70% of unaccompanied homeless youth are current smokers. Although a few studies have described smoking behavior among homeless youth, none have focused on how to help homeless youth quit smoking. As such, there are significant gaps in understanding their interest in quitting and what strategies might best fit their specific needs. METHODS: Unaccompanied homeless youth were randomly sampled from street sites in Los Angeles County (N = 292). All were current smokers who completed a survey on their smoking-related behaviors and cognitions. RESULTS: 65.7% of youth had quit for at least 24hr during the past year, and 43.4% were motivated to quit. Previous quit attempts tended to be unassisted, but 58.6% reported that they would be interested in formal cessation treatment. Multivariate analyses indicated that motivation to quit was higher among youth who were older, Black or Hispanic (vs. White), and who asked about smoking by a service provider, but it was lower among those who were more nicotine dependent. Being interested in cessation treatment was more likely among youth who were asked about smoking by a service provider, anticipated more barriers to quitting, and were motivated to quit; it was less likely among youth who had slept outdoors during the past 30 days. DISCUSSION: Smoking cessation is often considered a low priority for homeless youth. However, many are motivated to quit and are interested in smoking cessation products and services. Implications for developing and engaging homeless youth in cessation treatment are discussed.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Tucker,J.S., Shadel,W.G., Golinelli,D., Ewing,B., Mullins,L.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors