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Reduced Risk of Barrett's Esophagus in Statin Users: Case-Control Study and Meta-Analysis 2016 Department of Gastroenterology, Norfolk and Norwich University Hospital, Norwich, NR4 7UZ, UK. i.beales@uea.ac.uk.; School of Medicine, Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK. i.beales@uea.ac.uk.; Department of Gastroenter
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Digestive diseases and sciences
Periodical, Abbrev.
Dig.Dis.Sci.
Pub Date Free Form
Jan
Volume
61
Issue
1
Start Page
238
Other Pages
246
Notes
JID: 7902782; 0 (Anti-Inflammatory Agents, Non-Steroidal); 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors); R16CO5Y76E (Aspirin); OTO: NOTNLM; 2015/06/02 [received]; 2015/09/03 [accepted]; 2015/09/19 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1573-2568; 0163-2116
Accession Number
PMID: 26386857
Language
eng
SubFile
Journal Article; Meta-Analysis; AIM; IM
DOI
10.1007/s10620-015-3869-4 [doi]
Output Language
Unknown(0)
PMID
26386857
Abstract
BACKGROUND: Use of statins has been associated with a reduced incidence of esophageal adenocarcinoma in population-based studies. However there are few studies examining statin use and the development of Barrett's esophagus. AIM: The purpose of this study was to examine the association between statin use and the presence of Barrett's esophagus in patients having their first gastroscopy. METHODS: We have performed a case-control study comparing statin use between patients with, and without, an incident diagnosis of non-dysplastic Barrett's esophagus. Male Barrett's cases (134) were compared to 268 male age-matched controls in each of two control groups (erosive gastro-esophageal reflux and dyspepsia without significant upper gastrointestinal disease). Risk factor and drug exposure were established using standardised interviews. Logistic regression was used to compare statin exposure and correct for confounding factors. We performed a meta-analysis pooling our results with three other case-control studies. RESULTS: Regular statin use was associated with a significantly lower incidence of Barrett's esophagus compared to the combined control groups [adjusted OR 0.62 (95 % confidence intervals 0.37-0.93)]. This effect was more marked in combined statin plus aspirin users [adjusted OR 0.43 (95 % CI 0.21-0.89)]. The inverse association between statin or statin plus aspirin use and risk of Barrett's was significantly greater with longer duration of use. Meta-analysis of pooled data (1098 Barrett's, 2085 controls) showed that statin use was significantly associated with a reduced risk of Barrett's esophagus [pooled adjusted OR 0.63 (95 % CI 0.51-0.77)]. CONCLUSIONS: Statin use is associated with a reduced incidence of a new diagnosis of Barrett's esophagus.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Beales,I.L., Dearman,L., Vardi,I., Loke,Y.
Original/Translated Title
URL
Date of Electronic
20150919
PMCID
Editors
Evaluation of Bar and Nightclub Intervention to Decrease Young Adult Smoking in New Mexico 2016 Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, Califo
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Print(0)
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Journal Article
Periodical, Full
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Periodical, Abbrev.
J.Adolesc.Health
Pub Date Free Form
Aug
Volume
59
Issue
2
Start Page
222
Other Pages
229
Notes
CI: Copyright (c) 2016; JID: 9102136; OTO: NOTNLM; 2015/10/09 [received]; 2016/04/12 [revised]; 2016/04/15 [accepted]; 2016/06/03 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1879-1972; 1054-139X
Accession Number
PMID: 27265423
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.jadohealth.2016.04.003 [doi]
Output Language
Unknown(0)
PMID
27265423
Abstract
PURPOSE: Over 20% of young adults in New Mexico currently smoke. We evaluated cigarette smoking prevalence of young adult bar patrons during an anti-tobacco Social Branding intervention. METHODS: The Social Branding intervention used a smoke-free brand, "HAVOC," to compete with tobacco marketing within the "Partier" young adult peer crowd. A series of cross-sectional surveys were collected from adults aged 18-26 in bars and nightclubs in Albuquerque, New Mexico, from 2009 to 2013 using randomized time-location sampling. Multivariable multinomial regression using full information maximum likelihood estimation to account for missing data evaluated differences in daily and nondaily smoking during the intervention, controlling for demographics, other risk behaviors, and tobacco-related attitudes. RESULTS: Data were collected from 1,069 individuals at Time 1, and 720, 1,142, and 1,149 participants at Times 2, 3, and 4, respectively. Current smoking rates decreased from 47.5% at Time 1 to 37.5% at Time 4 (p
Descriptors
Links
Book Title
Database
Publisher
Society for Adolescent Health and Medicine. Published by Elsevier Inc
Data Source
Authors
Kalkhoran,S., Lisha,N.E., Neilands,T.B., Jordan,J.W., Ling,P.M.
Original/Translated Title
URL
Date of Electronic
20160603
PMCID
Editors
Temporal trends of esophageal disorders by age in the Cerner Health Facts database 2016 Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD. Electronic address: jessica.petrick@nih.gov.; Division of Gastroenterology, Department of Medicine, Hepatology and Nutrit
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Annals of Epidemiology
Periodical, Abbrev.
Ann.Epidemiol.
Pub Date Free Form
Feb
Volume
26
Issue
2
Start Page
151
Other Pages
4.e1-4
Notes
LR: 20160426; CI: Published by Elsevier Inc.; GR: T32 DK007150/DK/NIDDK NIH HHS/United States; GR: T32DK007150/DK/NIDDK NIH HHS/United States; GR: UL1 TR000050/TR/NCATS NIH HHS/United States; GR: UL1TR00005/TR/NCATS NIH HHS/United States; GR: ZIA CP010220
Place of Publication
United States
ISSN/ISBN
1873-2585; 1047-2797
Accession Number
PMID: 26762962
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; IM
DOI
10.1016/j.annepidem.2015.11.004 [doi]
Output Language
Unknown(0)
PMID
26762962
Abstract
PURPOSE: Esophageal adenocarcinoma incidence has increased approximately 600% over the last 4 decades in the United States. Little research has been conducted on the temporal trends of gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE), yet it is important to establish whether these conditions have also increased with time or differ by age. METHODS: The Cerner Health Facts((R)) database contains information on 35 million patients between 2001 and 2010. GERD, BE, and esophageal cancer (EC) cases were defined using International Classification of Diseases, ninth edition codes. We calculated age-adjusted rates and 95% confidence intervals for GERD, BE, and EC. RESULTS: In this population, the overall, all-age rate per 100,000 encounters for GERD was 711.9, BE was 21.6, and EC was 6.1. During 2001-2010, GERD rates increased by approximately 50% and EC rates more than doubled, but BE rates declined by approximately 40%. Trends were similar by age, and all rates were higher in Caucasians and males. CONCLUSIONS: These data indirectly support the idea that increased incidence of EC may be partially due to GERD and raise the provocative hypothesis that BE rates may be decreasing possibly as a forerunner of continued stabilization of esophageal adenocarcinoma rates and a possible subsequent decline.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Petrick,J.L., Nguyen,T., Cook,M.B.
Original/Translated Title
URL
Date of Electronic
20151211
PMCID
PMC4844025
Editors
Cohort study of electronic cigarette use: effectiveness and safety at 24 months 2016 Department of Medicine and Aging Sciences, University of Chieti, Chieti, Italy Local Health Unit of Pescara, Pescara, Italy "University G. d'Annunzio" Foundation, Chieti, Italy Regional Healthcare Agency of Abruzzo, Pescara, Italy.; Department of Medicine
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
6-Jun
Volume
Issue
Start Page
Other Pages
Notes
LR: 20160608; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/; JID: 9209612; OTO: NOTNLM; 2015/11/11 [rece
Place of Publication
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 27272748
Language
ENG
SubFile
JOURNAL ARTICLE
DOI
tobaccocontrol-2015-052822 [pii]
Output Language
Unknown(0)
PMID
27272748
Abstract
OBJECTIVE: To evaluate the safety and effectiveness of e-cigarettes, by comparing users of only e-cigarettes, smokers of only tobacco cigarettes and dual users. DESIGN: Prospective cohort study. We update previous 12-month findings and report the results of the 24-month follow-up. DATA SOURCES: Direct contact and questionnaires by phone or via internet. METHODS: Adults (30-75 years) were classified as: (1) tobacco smokers, if they smoked >/=1 tobacco cigarette/day, (2) e-cigarette users, if they inhaled >/=50 puffs/week of any type of e-cigarette and (3) dual users, if they smoked tobacco cigarettes and also used e-cigarettes. Carbon monoxide levels were tested in 50% of those declaring tobacco smoking abstinence. Hospital discharge data were used to validate possibly related serious adverse events in 46.0% of the sample. MAIN OUTCOME MEASURES: Sustained abstinence from tobacco cigarettes and/or e-cigarettes after 24 months, the difference in the number of tobacco cigarettes smoked daily between baseline and 24 months, possibly related serious adverse events. RESULTS: Data at 24 months were available for 229 e-cigarette users, 480 tobacco smokers and 223 dual users (overall response rate 68.8%). Of the e-cigarette users, 61.1% remained abstinent from tobacco (while 23.1% and 26.0% of tobacco-only smokers and dual users achieved tobacco abstinence). The rate (18.8%) of stopping use of either product (tobacco and/or e-cigarettes) was not higher for e-cigarette users compared with tobacco smokers or dual users. Self-rated health and adverse events were similar between all groups. Among those continuing to smoke, there were no differences in the proportion of participants reducing tobacco cigarette consumption by 50% or more, the average daily number of cigarettes and the average self-rated health by baseline group. Most dual users at baseline abandoned e-cigarettes and continued to smoke tobacco. Those who continued dual using or converted from tobacco smoking to dual use during follow-up experienced significant improvements in the 3 outcomes compared with those who continued or switched to only smoking tobacco (p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Manzoli,L., Flacco,M.E., Ferrante,M., La Vecchia,C., Siliquini,R., Ricciardi,W., Marzuillo,C., Villari,P., Fiore,M., ISLESE Working Group
Original/Translated Title
URL
Date of Electronic
20160606
PMCID
Editors
Gender difference in gastro-esophageal reflux diseases 2016 Kiyotaka Asanuma, Katsunori Iijima, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi Prefecture 980-8574, Japan.; Kiyotaka Asanuma, Katsunori Iijima, Tooru Shimosegawa, Division of Gastroenterology, To
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
World journal of gastroenterology
Periodical, Abbrev.
World J.Gastroenterol.
Pub Date Free Form
7-Feb
Volume
22
Issue
5
Start Page
1800
Other Pages
1810
Notes
LR: 20160210; JID: 100883448; OID: NLM: PMC4724611; OTO: NOTNLM; 2015/06/25 [received]; 2015/10/07 [revised]; 2015/12/30 [accepted]; ppublish
Place of Publication
United States
ISSN/ISBN
2219-2840; 1007-9327
Accession Number
PMID: 26855539
Language
eng
SubFile
Journal Article; Review; IM
DOI
10.3748/wjg.v22.i5.1800 [doi]
Output Language
Unknown(0)
PMID
26855539
Abstract
The incidence of esophageal adenocarcinoma (EAC) has risen sharply in western countries over the past 4 decades. This type of cancer is considered to follow a transitional process that goes from gastro-esophageal reflux disease (GERD) to Barrett's esophagus (BE, a metaplastic condition of the distal esophagus), a precursor lesion and ultimately adenocarcinoma. This spectrum of GERD is strongly predominant in males due to an unidentified mechanism. Several epidemiologic studies have described that the prevalence of GERD, BE and EAC in women is closely related to reproductive status, which suggests a possible association with the estrogen level. Recently, we revealed in an in vivo study that the inactivation of mast cells by the anti-inflammatory function of estrogen may account for the gender difference in the GERD spectrum. Other studies have described the contribution of female steroid hormones to the gender difference in these diseases. Estrogen is reported to modulate the metabolism of fat, and obesity is a main risk factor of GERDs. Moreover, estrogen could confer esophageal epithelial resistance to causative refluxate. These functions of estrogen might explain the approximately 20-year delay in the incidence of BE and the subsequent development of EAC in women compared to men, and this effect may be responsible for the male predominance. However, some observational studies demonstrated that hormone replacement therapy exerts controversial effects in GERD patients. Nevertheless, the estrogen-related endocrine milieu may prevent disease progression toward carcinogenesis in GERD patients. The development of innovative alternatives to conventional acid suppressors may become possible by clarifying the mechanisms of estrogen.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Asanuma,K., Iijima,K., Shimosegawa,T.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4724611
Editors
Determination of risk for Barrett's esophagus and esophageal adenocarcinoma 2016 aDepartment of Medicine, Section of Gastroenterology and HepatologybDan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Current opinion in gastroenterology
Periodical, Abbrev.
Curr.Opin.Gastroenterol.
Pub Date Free Form
Jul
Volume
32
Issue
4
Start Page
319
Other Pages
324
Notes
JID: 8506887; ppublish
Place of Publication
United States
ISSN/ISBN
1531-7056; 0267-1379
Accession Number
PMID: 27276368
Language
eng
SubFile
Journal Article; IM
DOI
10.1097/MOG.0000000000000274 [doi]
Output Language
Unknown(0)
PMID
27276368
Abstract
PURPOSE OF REVIEW: The incidence of esophageal adenocarcinoma and its precursor, Barrett's esophagus, have increased greatly over the past 40 years and continue to rise. This report summarizes the most recent data on the risk factors for Barrett's esophagus and esophageal adenocarcinoma. RECENT FINDINGS: Other factors, highly correlated with increasing trends for obesity, are the dominant driver of the increase in incidence of esophageal adenocarcinoma, interacting with gastroesophageal reflux disease symptoms. Abdominal obesity, independently of gastroesophageal reflux disease symptoms, is associated with increased risk of Barrett's esophagus and this association is likely mediated by high levels of leptin and insulin. Use of aspirin, nonsteroidal anti-inflammatory drugs, statins, and proton pump inhibitors are associated with a reduced risk of Barrett's esophagus as well as lower risk of neoplastic progression in patients with Barrett's esophagus. An increasing number of genetic loci have been associated with risk of Barrett's esophagus and esophageal adenocarcinoma. SUMMARY: Recent advances in identifying risk factors and reporting of more precise estimates of effect for the main risk factors will positively impact clinical risk stratification efforts for Barrett's esophagus and esophageal adenocarcinoma. Large pooling studies are underway to derive and validate reliable clinical risk models.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Thrift,A.P.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Impact of Partial and Comprehensive Smoke-Free Regulations on Indoor Air Quality in Bars 2016 Department of Environmental Health, Graduate School of Public Health, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea. xellos88@naver.com.; Department of Environmental Health Research, Seoul Medical Center, 156 Sinnae-ro, Jungnang-
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of environmental research and public health
Periodical, Abbrev.
Int.J.Environ.Res.Public.Health.
Pub Date Free Form
26-Jul
Volume
13
Issue
8
Start Page
10.3390/ijerph13080754
Other Pages
Notes
JID: 101238455; OTO: NOTNLM; 2016/05/30 [received]; 2016/07/16 [revised]; 2016/07/19 [accepted]; epublish
Place of Publication
Switzerland
ISSN/ISBN
1660-4601; 1660-4601
Accession Number
PMID: 27472349
Language
eng
SubFile
Journal Article; IM
DOI
10.3390/ijerph13080754 [doi]
Output Language
Unknown(0)
PMID
27472349
Abstract
In Korea, smoke-free regulations have been gradually implemented in bars based on venue size. Smoking bans were implemented in 2013 for bars >/=150 m(2), in 2014 for bars >/=100 m(2), and in 2015 for bars of all sizes. The purpose of this study was to determine indoor fine particle (PM2.5) concentrations in bars before and after implementation of the smoke-free policies based on venue size. Indoor PM2.5 concentrations were measured with real-time aerosol monitors at four time points: (1) pre-regulation (n = 75); (2) after implementing the ban in bars >/=150 m(2) (n = 75); (3) after implementing the ban in bars >/=100 m(2) (n = 107); and (4) when all bars were smoke-free (n = 79). Our results showed that the geometric mean of the indoor PM2.5 concentrations of all bars decreased from 98.4 mug/m(3) pre-regulation to 79.5, 42.9, and 26.6 mug/m(3) after the ban on smoking in bars >/=150 m(2), >/=100 m(2), and all bars, respectively. Indoor PM2.5 concentrations in bars of each size decreased only after the corresponding regulations were implemented. Although smoking was not observed in Seoul bars after smoking was banned in all bars, smoking was observed in 4 of 21 bars in Changwon. Our study concludes that the greatest decrease in PM2.5 concentrations in bars was observed after the regulation covering all bars was implemented. However, despite the comprehensive ban, smoking was observed in bars in Changwon. Strict compliance with the regulations is needed to improve indoor air quality further.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Kim,J., Ban,H., Hwang,Y., Ha,K., Lee,K.
Original/Translated Title
URL
Date of Electronic
20160726
PMCID
Editors
Preventive malaria treatment for contacts of patients with Ebola virus disease in the context of the west Africa 2014-15 Ebola virus disease response: an economic analysis 2016 National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA; Modeling Unit, Emergency Operations Center, 2014 Ebola Response, Centers for Disease Control and Prevention, Atlanta, GA, USA; IHR
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Lancet.Infectious diseases
Periodical, Abbrev.
Lancet Infect.Dis.
Pub Date Free Form
Apr
Volume
16
Issue
4
Start Page
449
Other Pages
458
Notes
CI: Copyright (c) 2016; JID: 101130150; 0 (Antimalarials); CIN: Lancet Infect Dis. 2016 Apr;16(4):391-2. PMID: 26706715; 2015/08/07 [received]; 2015/10/24 [revised]; 2015/11/05 [accepted]; 2015/12/17 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1474-4457; 1473-3099
Accession Number
PMID: 26706716
Language
eng
SubFile
Journal Article; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1016/S1473-3099(15)00465-X [doi]
Output Language
Unknown(0)
PMID
26706716
Abstract
BACKGROUND: After the detection of an Ebola virus disease outbreak in west Africa in 2014, one of the elements of the response was to contact trace and isolate patients in specialised Ebola treatment units (ETUs) at onset of fever. We aimed to assess the economic feasibility of administering preventive malaria treatment to all contacts of patients with Ebola virus disease, to prevent the onset of febrile malaria and subsequent admission to ETUs. METHODS: We used a decision tree model to analyse the costs of preventive malaria treatment (artemisinin-based combination treatment [ACT]) for all contacts of patients with Ebola virus disease (in terms of administration and averted ETU-stay costs) and benefits (in terms of averted ETU admissions) in west Africa, from a health-care provider perspective. The period of analyses was 1 year, which is roughly similar to the duration of the 2014-15 west Africa Ebola outbreak response. We calculated the intervention's cost per ETU admission averted (average cost-effectiveness ratio) by season (wet and dry), country (Liberia, Sierra Leone, and Guinea), and age of contact (/=15 years). We did sensitivity analyses to assess how results varied with malaria parasite prevalence (in children aged 2-10 years), daily cost of ETU stay (for Liberian malaria incidence levels), and compliance and effectiveness of preventive malaria treatment. FINDINGS: Administration of ACTs to contacts of patients with Ebola virus disease was cost saving for contacts of all ages in Liberia, Sierra Leone, and Guinea, in both seasons, from a health-care provider perspective. In the wet season, preventive malaria treatment was estimated to reduce the probability of a contact being admitted to an ETU by a maximum of 36% (in Guinea, for contacts aged /=15 years). Assuming 85% compliance and taking into account the African population pyramid, the intervention is expected to be cost saving in contacts of all age groups in areas with malaria parasite prevalence in children aged 2-10 years as low as 10%. In Liberia during the wet season, malaria preventive treatment was cost saving even when average daily bed-stay costs were as low as US$5 for children younger than 5 years, $9 for those aged 5-14 years, and $22 for those aged 15 years or older. INTERPRETATION: Administration of preventive malaria treatment to contacts of patients with Ebola virus disease should be considered by public health officials when addressing Ebola virus disease outbreaks in countries and seasons where malaria reaches high levels of transmission. FUNDING: Centers for Disease Control and Prevention.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Carias,C., Greening,B.,Jr, Campbell,C.G., Meltzer,M.I., Hamel,M.J.
Original/Translated Title
URL
Date of Electronic
20151217
PMCID
Editors
High prevalence of extended-spectrum and plasmidic AmpC beta-lactamase-producing Escherichia coli from poultry in Tunisia 2016 University of Tunis El Manar, Faculty of Medicine of Tunis-Research Laboratory <<Antimicrobial resistance>>, Tunis, Tunisia.; University of Tunis El Manar, Faculty of Medicine of Tunis-Research Laboratory <<Antimicrobial resistance>>, Tunis, Tunisia; Univ
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of food microbiology
Periodical, Abbrev.
Int.J.Food Microbiol.
Pub Date Free Form
16-Aug
Volume
231
Issue
Start Page
69
Other Pages
75
Notes
CI: Copyright (c) 2016; JID: 8412849; OTO: NOTNLM; 2015/12/16 [received]; 2016/04/29 [revised]; 2016/05/02 [accepted]; 2016/05/03 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1879-3460; 0168-1605
Accession Number
PMID: 27220012
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.ijfoodmicro.2016.05.001 [doi]
Output Language
Unknown(0)
PMID
27220012
Abstract
This study was conducted to detect extended spectrum beta-lactamases (ESBLs) and plasmidic AmpC beta-lactamase (pAmpC-BL)-producing Escherichia coli isolates in industrial poultry samples were collected from healthy chickens of the three farms. Samples were inoculated onto desoxycholate-lactose-agar plates supplemented with cefotaxime (2mg/L). E. coli was identified by biochemical and molecular methods and antibiotic susceptibility testing by the disk diffusion method. Genes encoding ESBLs and pAmpC-BL were detected by PCR and sequencing. Phylogenetic groups were determined by triplex PCR. The molecular typing of strains was done by pulsed field gel electrophoresis (PFGE) and Multilocus Sequence Typing (MLST) in those isolates showing different PFGE patterns. Cefotaxime-resistant E. coli isolates were recovered in 48 of 137 fecal samples (35%), and one isolate/sample was further studied. The following beta-lactamase genes were detected: blaCTX-M-1 (29 isolates, isolated in all three farms), blaCTX-M-15 (5 isolates, confined in farm II), blaCTX-M-14 and blaCMY-2 (one isolate and 13 isolates, respectively, in farm III). The 48 cefotaxime-resistant isolates were distributed into phylogroups: B1 (n=21), A (n=15) and D (n=12). PFGE analysis revealed 19 unrelated patterns: 15 different profiles among ESBL-positive strains and 4 among the CMY-2-positive isolates. The following sequence types-associated phylogroups were detected: a) CTX-M-1-positive strains: lineages ST542-B1, ST212-B1, ST58-B1, ST155-B1 and ST349-D; b) CTX-M-15-positive strain: lineage ST405-D; c) CTX-M-14-positive strain: lineage ST1056-B1; d) CMY-2-positive strains: lineages ST117-D, ST2197-A, and ST155-B1. Healthy chickens constitute an important reservoir of ESBL- and pAmpC-BL-producing E. coli isolates that potentially could be transmitted to humans via the food chain or by direct contact.
Descriptors
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Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Maamar,E., Hammami,S., Alonso,C.A., Dakhli,N., Abbassi,M.S., Ferjani,S., Hamzaoui,Z., Saidani,M., Torres,C., Boutiba-Ben Boubaker,I.
Original/Translated Title
URL
Date of Electronic
20160503
PMCID
Editors
Evaluation of microtensile and tensile bond strength tests determining effects of erbium, chromium: yttrium-scandium-gallium-garnet laser pulse frequency on resin-enamel bonding 2016 Department of Restorative Dentistry, Faculty of Dentsitry, Karadeniz Technical University, Trabzon, Turkey.; Department of Restorative Dentistry, Faculty of Dentsitry, Biruni University, Istanbul, Turkey.; Department of Restorative Dentistry, Faculty of D
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nigerian journal of clinical practice
Periodical, Abbrev.
Niger.J.Clin.Pract.
Pub Date Free Form
Sep-Oct
Volume
19
Issue
5
Start Page
585
Other Pages
590
Notes
JID: 101150032; ppublish
Place of Publication
India
ISSN/ISBN
1119-3077
Accession Number
PMID: 27538544
Language
eng
SubFile
Journal Article; IM
DOI
10.4103/1119-3077.188702 [doi]
Output Language
Unknown(0)
PMID
27538544
Abstract
OBJECTIVES: The aim of the present study was to compare two different bond strength test methods (tensile and microtensile) in investing the influence of erbium, chromium: yttrium-scandium-gallium-garnet (Er, Cr: YSGG) laser pulse frequency on resin-enamel bonding. MATERIALS AND METHODS: One-hundred and twenty-five bovine incisors were used in the present study. Two test methods were used: Tensile bond strength (TBS; n = 20) and micro-TBS (muTBS; n = 5). Those two groups were further split into three subgroups according to Er, Cr: YSGG laser frequency (20, 35, and 50 Hz). Following adhesive procedures, microhybrid composite was placed in a custom-made bonding jig for TBS testing and incrementally for muTBS testing. TBS and muTBS tests were carried out using a universal testing machine and a microtensile tester, respectively. RESULTS: Analysis of TBS results showed that means were not significantly different. For muTBS, the Laser-50 Hz group showed the highest bond strength (P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Yildirim,T., Ayar,M.K., Yesilyurt,C., Kilic,S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors