WTS database

Title	Pub Year Sort ascending	Author	SearchLink
Application of a new parameter in the 6-minute walk test for manifold analysis of exercise capacity in patients with COPD	2014	Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan.; Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan.; Department of Sports Medicine, Graduate School of	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of chronic obstructive pulmonary disease Periodical, Abbrev. Int.J.Chron.Obstruct Pulmon Dis. Pub Date Free Form 3-Nov Volume 9 Issue Start Page 1235 Other Pages 1240 Notes LR: 20151119; JID: 101273481; 0 (Biomarkers); S88TT14065 (Oxygen); OID: NLM: PMC4224096; OTO: NOTNLM; 2014 [ecollection]; 2014/11/03 [epublish]; epublish Place of Publication New Zealand ISSN/ISBN 1178-2005; 1176-9106 Accession Number PMID: 25395845 Language eng SubFile Journal Article; IM DOI 10.2147/COPD.S71383 [doi] Output Language Unknown(0) PMID 25395845 Abstract BACKGROUND: New parameters in the 6-minute walk test (6 MWT) are required for comprehensive analysis of exercise capacity in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to apply a novel index, the desaturation distance ratio (DDR), to clinical research on COPD as an estimate of exercise capacity and to examine whether DDR is a potential parameter for manifold analysis of exercise capacity in patients with COPD. METHODS: A total of 41 patients with COPD (median age [interquartile range] =75 [68-79] years; and body mass index [BMI] =22.3 [19.4-23.8] kg/m(2)) participated in the study. The 6 MWT was performed along with anthropometric measurements and a pulmonary function test. The "desaturation area" was measured as the total area above the curve created using peripheral oxygen saturation (SpO2) values observed at each minute during the 6 MWT. Then the DDR was calculated as the ratio of the desaturation area to the 6-minute walk distance (6 MWD). RESULTS: The 6 MWD was 370 (328-445) m, and the decline in SpO2 values (DeltaSpO2) was -5.0% (-8.0% to -1.5%). The DDR correlated modestly with baseline pulmonary function in patients with COPD (forced expiratory volume in 1 second [% of predicted value]: r=-0.658, P Descriptors Links Book Title Database Publisher Data Source Authors Ijiri,N., Kanazawa,H., Yoshikawa,T., Hirata,K. Original/Translated Title URL Date of Electronic 20141103 PMCID PMC4224096 Editors
Predictors of illicit drug/s use among university students in Northern Ireland, Wales and England	2014	University of Gloucestershire, Faculty of Applied Sciences. walidansari@glos.ac.uk.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Global journal of health science Periodical, Abbrev. Glob.J.Health.Sci. Pub Date Free Form 16-Dec Volume 7 Issue 4 Start Page 18 Other Pages 29 Notes LR: 20160428; JID: 101519495; 0 (Street Drugs); OID: NLM: PMC4802112; 2014/10/30 [received]; 2014/11/17 [accepted]; epublish Place of Publication Canada ISSN/ISBN 1916-9736; 1916-9736 Accession Number PMID: 25946914 Language eng SubFile Journal Article; IM DOI 10.5539/gjhs.v7n4p18 [doi] Output Language Unknown(0) PMID 25946914 Abstract INTRODUCTION: The use of illicit drug/s among university students is a public health concern. Nevertheless, many UK studies investigated a narrow spectrum of variables to explore their association/s with illicit drug/s use. METHODS: We assessed the associations between a wide range of socio-demographic, health and wellbeing variables (independent variables) and having used illicit drug/s regularly, occasionally or never in life (dependent variables). Data (3706 students) were collected from seven universities in England, Wales, and Northern Ireland, using a self-administered questionnaire. RESULTS: About 5% of the sample had regularly used illicit drug/s, 25% occasionally, and 70% never. Regular drug use (RDU) was significantly more likely among males aged 21-29 years, daily smokers, those with heavy episodic drinking or possible alcohol dependency (CAGE test), and those who perceived their academic performance better than their peers. RDU was less likely among students with high health awareness and those living with parents. The predictors of occasional drug use (ODU) were similar to those of RDU. However, in addition, students with higher perceived stress were less likely, and students who felt financial burden/s were more likely to report ODU, while no association with academic performance was found. Never use of illicit drug/s was inversely associated with most of the variables listed above, and was positively associated with religiosity. Illicit drug/s use goes along with other substance use (alcohol and smoking). The finding that illicit drug/s use was higher among students reporting good academic performance was surprising and raises the question of whether illicit drug/s may be used as performance enhancing drugs. CONCLUSION: The factors identified with illicit drug/s use in this study could be utilized to develop appropriate public health policies and preventive measures for the health of students. Multilevel, value based, comprehensive, and strategic long-term intervention plans are required. This could include social interventions aimed at generating recreations alternatives and opportunities for youth, and a critical review for current authorities' interventions and services. Suggestions for coping with problems of campus illicit drug use/abuse also need to be offered. Descriptors Links Book Title Database Publisher Data Source Authors El Ansari,W., Vallentin-Holbech,L., Stock,C. Original/Translated Title URL Date of Electronic 20141216 PMCID PMC4802112 Editors
Real-world effectiveness of e-cigarettes when used to aid smoking cessation: a cross-sectional population study	2014	Cancer Research UK Health Behaviour Research Centre, University College London, London, UK; Department of Clinical, Educational and Health Psychology, University College London, London, UK.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addiction (Abingdon, England) Periodical, Abbrev. Addiction Pub Date Free Form Sep Volume 109 Issue 9 Start Page 1531 Other Pages 1540 Notes LR: 20151215; CI: (c) 2014; GR: 14135/Cancer Research UK/United Kingdom; GR: MR/K023195/1/Medical Research Council/United Kingdom; JID: 9304118; OID: NLM: PMC4171752; OTO: NOTNLM; 2014/02/27 [received]; 2014/04/08 [revised]; 2014/05/12 [accepted]; ppublis Place of Publication England ISSN/ISBN 1360-0443; 0965-2140 Accession Number PMID: 24846453 Language eng SubFile Journal Article; IM DOI 10.1111/add.12623 [doi] Output Language Unknown(0) PMID 24846453 Abstract BACKGROUND AND AIMS: Electronic cigarettes (e-cigarettes) are rapidly increasing in popularity. Two randomized controlled trials have suggested that e-cigarettes can aid smoking cessation, but there are many factors that could influence their real-world effectiveness. This study aimed to assess, using an established methodology, the effectiveness of e-cigarettes when used to aid smoking cessation compared with nicotine replacement therapy (NRT) bought over-the-counter and with unaided quitting in the general population. DESIGN AND SETTING: A large cross-sectional survey of a representative sample of the English population. PARTICIPANTS: The study included 5863 adults who had smoked within the previous 12 months and made at least one quit attempt during that period with either an e-cigarette only (n = 464), NRT bought over-the-counter only (n = 1922) or no aid in their most recent quit attempt (n = 3477). MEASUREMENTS: The primary outcome was self-reported abstinence up to the time of the survey, adjusted for key potential confounders including nicotine dependence. FINDINGS: E-cigarette users were more likely to report abstinence than either those who used NRT bought over-the-counter [odds ratio (OR) = 2.23, 95% confidence interval (CI) = 1.70-2.93, 20.0 versus 10.1%] or no aid (OR = 1.38, 95% CI = 1.08-1.76, 20.0 versus 15.4%). The adjusted odds of non-smoking in users of e-cigarettes were 1.63 (95% CI = 1.17-2.27) times higher compared with users of NRT bought over-the-counter and 1.61 (95% CI = 1.19-2.18) times higher compared with those using no aid. CONCLUSIONS: Among smokers who have attempted to stop without professional support, those who use e-cigarettes are more likely to report continued abstinence than those who used a licensed NRT product bought over-the-counter or no aid to cessation. This difference persists after adjusting for a range of smoker characteristics such as nicotine dependence. Descriptors Links Book Title Database Publisher The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction Data Source Authors Brown,J., Beard,E., Kotz,D., Michie,S., West,R. Original/Translated Title URL Date of Electronic PMCID PMC4171752 Editors
(E)-2-{[4-(Di-methyl-amino)-benzyl-idene]amino}-5-nitro-phenol	2014	Chemistry Department, Morgan State University, 1700 East Cold Spring Lane, Baltimore, MD 21251, USA.; Department of Chemistry, Howard University, 525 College Street NW, Washington, DC 20059, USA.; Department of Chemistry, Keene State College, Keene, NH 03	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 26-Apr Volume 70 Issue Pt 5 Start Page o598 Other Pages 9 Notes LR: 20140528; JID: 101089178; OID: NLM: PMC4011306; 2014/05/01 [ecollection]; 2014/03/04 [received]; 2014/04/16 [accepted]; 2014/04/26 [epublish]; epublish Place of Publication United States ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 24860394 Language eng SubFile Journal Article DOI 10.1107/S160053681400871X [doi] Output Language Unknown(0) PMID 24860394 Abstract The title Schiff base compound, C15H15N3O3, crystallizes with two mol-ecules (A and B) in the asymmetric unit. Each mol-ecule adopts an E conformation around the C= N imine bond. The two mol-ecules have minor differences in their conformations. In mol-ecule A, the dihedral angle between the nitro group and its benzene ring is 2.1 (2) degrees and that between the two benzene rings is 0.88 (7) degrees , while the corresponding angles for mol-ecule B are 5.7 (1) and 2.45 (6) degrees , respectively. In each mol-ecule, there is an intra-molecular O-Hcdots, three dots, centeredN hydrogen bond. In the crystal, inversion-related mol-ecules are linked via O-Hcdots, three dots, centeredO hydrogen bonds forming A-A and B-B dimers. These dimers are linked via C-Hcdots, three dots, centeredO hydrogen bonds involving the nitro O atoms, forming A-A-A and B-B-B slabs that lie parallel to one another and to (010). Descriptors Links Book Title Database Publisher Data Source Authors Hijji,Y., Butcher,R.J., Jasinski,J.P. Original/Translated Title URL Date of Electronic 20140426 PMCID PMC4011306 Editors
Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review	2014	Section of Gastroenterology and Hepatology, Houston Veterans Affairs Medical Center (152), , Houston, Texas, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Gut Periodical, Abbrev. Gut Pub Date Free Form Jun Volume 63 Issue 6 Start Page 871 Other Pages 880 Notes LR: 20150423; GR: DK58338/DK/NIDDK NIH HHS/United States; GR: K24 DK078154/DK/NIDDK NIH HHS/United States; GR: K24-04-107/PHS HHS/United States; GR: P30 DK056338/DK/NIDDK NIH HHS/United States; GR: T32 DK083266/DK/NIDDK NIH HHS/United States; JID: 2985108 Place of Publication England ISSN/ISBN 1468-3288; 0017-5749 Accession Number PMID: 23853213 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review; AIM; IM DOI 10.1136/gutjnl-2012-304269 [doi] Output Language Unknown(0) PMID 23853213 Abstract OBJECTIVE: To update the findings of the 2005 systematic review of population-based studies assessing the epidemiology of gastro-oesophageal reflux disease (GERD). DESIGN: PubMed and Embase were screened for new references using the original search strings. Studies were required to be population-based, to include >/= 200 individuals, to have response rates >/= 50% and recall periods Descriptors Links Book Title Database Publisher Data Source Authors El-Serag,H.B., Sweet,S., Winchester,C.C., Dent,J. Original/Translated Title URL Date of Electronic 20130713 PMCID PMC4046948 Editors
Detection and molecular characterization of Escherichia coli CTX-M-15 and Klebsiella pneumoniae SHV-12 beta-lactamases from bovine mastitis isolates in the United Kingdom	2014	School of Veterinary Science, University of Liverpool, Leahurst, Cheshire, United Kingdom.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Volume 58 Issue 2 Start Page 789 Other Pages 794 Notes LR: 20150422; JID: 0315061; 0 (Bacterial Proteins); 0 (beta-Lactams); EC 3.5.2.- (beta-lactamase CTX-M-15); EC 3.5.2.- (beta-lactamase SHV-12); EC 3.5.2.6 (beta-Lactamases); OID: NLM: PMC3910873; 2013/11/18 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 24247146 Language eng SubFile Journal Article; IM DOI 10.1128/AAC.00752-13 [doi] Output Language Unknown(0) PMID 24247146 Abstract Recent reports raised concerns about the role that farm stock may play in the dissemination of extended-spectrum beta-lactamase (ESBL)-producing bacteria. This study characterized the ESBLs in two Escherichia coli and three Klebsiella pneumoniae subsp. pneumoniae isolates from cases of clinical bovine mastitis in the United Kingdom. Bacterial culture and sensitivity testing of bovine mastitic milk samples identified Gram-negative cefpodoxime-resistant isolates, which were assessed for their ESBL phenotypes. Conjugation experiments and PCR-based replicon typing (PBRT) were used for characterization of transferable plasmids. E. coli isolates belonged to sequence type 88 (ST88; determined by multilocus sequence typing) and carried blaCTX-M-15 and blaTEM-1, while K. pneumoniae subsp. pneumoniae isolates carried blaSHV-12 and blaTEM-1. Conjugation experiments demonstrated that blaCTX-M-15 and blaTEM-1 were carried on a conjugative plasmid in E. coli, and PBRT identified this to be an IncI1 plasmid. The resistance genes were nontransferable in K. pneumoniae subsp. pneumoniae isolates. Moreover, in the E. coli isolates, an association of ISEcp1 and IS26 with blaCTX-M-15 was found where the IS26 element was inserted upstream of both ISEcp1 and the blaCTX-M promoter, a genetic arrangement highly similar to that described in some United Kingdom human isolates. We report the first cases in Europe of bovine mastitis due to E. coli CTX-M-15 and also of bovine mastitis due to K. pneumoniae subsp. pneumoniae SHV-12 beta-lactamases in the United Kingdom. We also describe the genetic environment of blaCTX-M-15 and highlight the role that IncI1 plasmids may play in the spread and dissemination of ESBL genes, which have been described in both human and cattle isolates. Descriptors Links Book Title Database Publisher Data Source Authors Timofte,D., Maciuca,I.E., Evans,N.J., Williams,H., Wattret,A., Fick,J.C., Williams,N.J. Original/Translated Title URL Date of Electronic 20131118 PMCID PMC3910873 Editors
Prevalence and determinants of susceptibility to cigarette smoking among school students in Pakistan: secondary analysis of Global Youth Tobacco Survey	2014	School of Public Health, Dow University of Health Sciences, OJHA Campus, SUPARCO road, Gulzar e Hijri, Karachi, Pakistan. kashif.shafique@glasgow.ac.uk.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Substance abuse treatment, prevention, and policy Periodical, Abbrev. Subst.Abuse Treat.Prev.Policy. Pub Date Free Form 21-Feb Volume 9 Issue Start Page 10 Other Pages 597X-9-10 Notes LR: 20150515; JID: 101258060; OID: NLM: PMC3936926; 2013/11/04 [received]; 2014/02/18 [accepted]; 2014/02/21 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1747-597X; 1747-597X Accession Number PMID: 24555481 Language eng SubFile Journal Article; IM DOI 10.1186/1747-597X-9-10 [doi] Output Language Unknown(0) PMID 24555481 Abstract BACKGROUND: Susceptibility to smoke has been recognized as a strong predictor of smoking experimentation and taking up regular smoking habit. The identification of smoking susceptible individuals and its determinants is important in the efforts to reduce future smoking prevalence. The aims of this study are to estimate prevalence of susceptibility to smoke among adolescents, and identify factors associated with it. METHODS: Cross sectional data was obtained from Global Youth Tobacco Survey conducted in three cities of Pakistan in year 2004. Study population consisted of students in grades, 8th, 9th, and 10th; aged 13 to 15 years. Secondary analysis using univariate and multivariate logistic regression analyses were performed to estimate the associations between smoking susceptibility and co-variates. Descriptive statistics were reported in proportions, and adjusted odds ratios with 95% confidence interval were used to report logistic regression analyses. RESULTS: Approximately 12% of nonsmoking students were found susceptible to smoking. Students, who were females (OR = 1.53, 95% CI [1.24-1.89]); whose parents (OR = 1.64, 95% CI [1.35-1.99]); or close friend smoked (OR = 2.77, 95% CI [2.27- 3.40]) were more susceptible to cigarette smoking. Students who had good knowledge about harmful effects of smoking (OR = 0.54, 95% CI [0.43-0.69]); and had access to anti-smoking media (OR = 0.73, 95% CI [0.59-0.89]) were less likely to be susceptible to smoking. CONCLUSION: Students who were females, had smoking parents, friends or exposure to newspaper/magazines cigarette marketing, were more susceptible to cigarette smoking among Pakistani adolescents. While knowledge of harmful effects of smoking and access to anti-smoking media served as protective factors against susceptibility to smoking. Descriptors Links Book Title Database Publisher Data Source Authors Aslam,S.K., Zaheer,S., Rao,S., Shafique,K. Original/Translated Title URL Date of Electronic 20140221 PMCID PMC3936926 Editors
The next generation of users: prevalence and longitudinal patterns of tobacco use among US young adults	2014	Amanda Richardson, Jessica Rath, and Donna Vallone are with the Department of Research and Evaluation, Legacy, Washington, DC, and the Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Valerie Will	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Public Health Periodical, Abbrev. Am.J.Public Health Pub Date Free Form Aug Volume 104 Issue 8 Start Page 1429 Other Pages 1436 Notes LR: 20150805; GR: HHSN271201100027C/PHS HHS/United States; JID: 1254074; OID: NLM: PMC4103202; 2014/06/12 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1541-0048; 0090-0036 Accession Number PMID: 24922152 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; AIM; IM DOI 10.2105/AJPH.2013.301802 [doi] Output Language Unknown(0) PMID 24922152 Abstract OBJECTIVES: We monitored the prevalence and patterns of use of the array of tobacco products available to young adults, who are at risk for initiation and progression to established tobacco use. METHODS: We used data from waves 1 to 3 of GfK's KnowledgePanel (2011-2012), a nationally representative cohort of young adults aged 18 to 34 years (n = 2144). We examined prevalence and patterns of tobacco product use over time, associated demographics, and state-level tobacco policy. We used multivariable logistic regression to determine predictors of initiation of cigarettes as well as noncombustible and other combustible products. RESULTS: The prevalence of ever tobacco use rose from 57.28% at wave 1 to 67.43% at wave 3. Use of multiple products was the most common pattern (66.39% of tobacco users by wave 3). Predictors of initiation differed by product type and included age, race/ethnicity, policy, and use of other tobacco products. CONCLUSIONS: Tobacco use is high among young adults and many are using multiple products. Efforts to implement policy and educate young adults about the risks associated with new and emerging products are critical to prevent increased initiation of tobacco use. Descriptors Links Book Title Database Publisher Data Source Authors Richardson,A., Williams,V., Rath,J., Villanti,A.C., Vallone,D. Original/Translated Title URL Date of Electronic 20140612 PMCID PMC4103202 Editors
MicroRNA Expression can be a Promising Strategy for the Detection of Barrett's Esophagus: A Pilot Study	2014	1] Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri, USA [2] University of Kansas Medical Center, Kansas City, Kansas, USA [3] Kansas Cancer Institute, Kansas City, Kansas, USA.; Department of Molecular a	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Clinical and translational gastroenterology Periodical, Abbrev. Clin.Transl.Gastroenterol. Pub Date Free Form 11-Dec Volume 5 Issue Start Page e65 Other Pages Notes LR: 20141231; JID: 101532142; OID: NLM: PMC4274369; 2014/08/15 [received]; 2014/11/10 [accepted]; epublish Place of Publication United States ISSN/ISBN 2155-384X Accession Number PMID: 25502391 Language eng SubFile Journal Article DOI 10.1038/ctg.2014.17 [doi] Output Language Unknown(0) PMID 25502391 Abstract OBJECTIVES: Patient outcomes for esophageal adenocarcinoma (EAC) have not improved despite huge advances in endoscopic therapy because cancers are being diagnosed late. Barrett's esophagus (BE) is the primary precursor lesion for EAC, and thus the non-endoscopic molecular diagnosis of BE can be an important approach to improve EAC outcomes if robust biomarkers for timely diagnosis are identified. MicroRNAs (miRNAs) are tissue-specific novel biomarkers that regulate gene expression and may satisfy this requirement. METHODS: Patients with gastroesophageal reflux disease (GERD) and BE were selected from an ongoing tissue and serum repository. BE was defined by the presence of intestinal metaplasia. Previously published miRNA sequencing profiles of GERD and BE patients allowed us to select three miRNAs, miR-192-5p, -215-5p, and -194-5p, for further testing in a discovery cohort and an independent validation cohort. Receiver operating curves were generated to calculate the diagnostic accuracy of these miRNAs for BE diagnosis. To test specificity, the miRNA signature was compared with those of the gastric cardia epithelium and the non-intestinal-type columnar epithelium (another definition of BE). In addition, to gain insights into BE origin (intestinal vs non-intestinal), global BE miRNA profiles were compared with the published miRNA profiles of other columnar epithelia in the gastrointestinal tract, that is, normal stomach and small and large intestine. RESULTS: The discovery cohort included 67 white male patients (40 with GERD and 27 with BE). The validation cohort included 28 patients (19 with GERD and 11 with BE). In the discovery cohort, the sensitivity, specificity and area under the curve (AUC) of the three mRNAs for BE diagnosis were 92-100%, 94-95%, and 0.96-0.97, respectively. During validation, the sensitivity and specificity of miRNAs for BE diagnosis were as follows: miR-192-5p, 92% and 94%, AUC 0.94 (0.80-0.99, P=0.0004); miR-215-5p, 100% and 94%, AUC 0.98 (0.84-1, P=0.0004); and miR-194-5p, 91% and 94%, AUC 0.96 (0.80-0.99, P=0.0001), respectively. The tested miRNAs identified all BE patients in both the discovery and the validation cohorts. When compared with non intestinal-type columnar and gastric cardia epithelia, the miRNA signature was specific to the intestinal-type columnar epithelium. Comparisons of BE miRNA sequencing data to published data sets for the normal stomach, small intestine and large intestine confirmed that two of the three miRNAs (miR-215-5p and -194-5p) were specific to the intestinal-type epithelium. CONCLUSIONS: MicroRNAs are highly accurate for detecting intestinal-type BE epithelia and should be tested further for the non-endoscopic molecular diagnosis of BE. Descriptors Links Book Title Database Publisher Data Source Authors Bansal,A., Hong,X., Lee,I.H., Krishnadath,K.K., Mathur,S.C., Gunewardena,S., Rastogi,A., Sharma,P., Christenson,L.K. Original/Translated Title URL Date of Electronic 20141211 PMCID PMC4274369 Editors
Effectiveness of lifestyle change plus dental care (LCDC) program on improving glycemic and periodontal status in the elderly with type 2 diabetes	2014	Health center 54, Bangkok, Thailand. saruta79@gmail.com.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC oral health Periodical, Abbrev. BMC Oral Health. Pub Date Free Form 16-Jun Volume 14 Issue Start Page 72 Other Pages 6831-14-72 Notes LR: 20151119; JID: 101088684; 0 (Blood Glucose); 0 (Hemoglobin A, Glycosylated); OID: NLM: PMC4069273; 2014/02/27 [received]; 2014/06/09 [accepted]; 2014/06/16 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1472-6831; 1472-6831 Accession Number PMID: 24934646 Language eng SubFile Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; D; IM DOI 10.1186/1472-6831-14-72 [doi] Output Language Unknown(0) PMID 24934646 Abstract BACKGROUND: Currently, there is an increased prevalence of diabetes mellitus among the elderly. To minimize adverse effects on glycemic control, prevention and management of general and oral complications in diabetic patients is essential. The purpose of the present study is to assess the effectiveness of a Lifestyle Change plus Dental Care (LCDC) program to improve glycemic and periodontal status in the elderly with type 2 diabetes. METHODS: A quasi-experimental study was conducted in Health Centers 54 (intervention) and 59 (control) from October 2013 to January 2014. 66 diabetic patients per health center were included. At baseline, the intervention group attended a 20 minute lifestyle and oral health education program, individual lifestyle counseling using motivational interviewing (MI), application of self regulation manual, and individual oral hygiene instruction. The intervention group received booster education every visit by viewing a 15 minute educational video. The control group received a routine program. Participants were assessed at baseline and 3 month follow up for glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), body mass index (BMI), periodontal status, knowledge, attitude and practice of oral health and diabetes mellitus. Data were analyzed by using descriptive statistic, Chi-square test, Fisher's exact test, t-test, and multiple linear regression. RESULTS: After the 3 month follow up, a multiple linear regression analysis showed that the intervention group was significantly negatively correlated in both glycemic and periodontal status. Participants in the intervention group had significantly lower glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), plaque index score, gingival index score, pocket depth, clinical attachment level (CAL), and percentage of bleeding on probing (BOP) when compared to the control group. CONCLUSIONS: The combination of lifestyle change and dental care in one program improved both glycemic and periodontal status in the elderly with type 2 diabetes. TRIAL REGISTRATION: ClinicalTrials.in.th: TCTR20140602001. Descriptors Links Book Title Database Publisher Data Source Authors Saengtipbovorn,S., Taneepanichskul,S. Original/Translated Title URL Date of Electronic 20140616 PMCID PMC4069273 Editors

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