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Establishment of a community care center for isolation and management of Ebola patients - Bomi County, Liberia, October 2014 2014
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Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
7-Nov
Volume
63
Issue
44
Start Page
1010
Other Pages
1012
Notes
JID: 7802429; ppublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 25375073
Language
eng
SubFile
Journal Article; IM
DOI
mm6344a6 [pii]
Output Language
Unknown(0)
PMID
25375073
Abstract
As of October 29, 2014, a total of 6,454 Ebola virus disease (Ebola) cases had been reported in Liberia by the Liberian Ministry of Health and Social Welfare, with 2,609 deaths. Although the national strategy for combating the ongoing Ebola epidemic calls for construction of Ebola treatment units (ETUs) in all 15 counties of Liberia, only a limited number are operational, and most of these are within Montserrado County. ETUs are intended to improve medical care delivery to persons whose illnesses meet Ebola case definitions, while also allowing for the safe isolation of patients to break chains of transmission in the community. Until additional ETUs are constructed, the Ministry of Health and Social Welfare is supporting development of community care centers (CCCs) for isolation of patients who are awaiting Ebola diagnostic test results and for provision of basic care (e.g., oral rehydration salts solutions) to patients confirmed to have Ebola who are awaiting transfer to ETUs. CCCs often have less bed capacity than ETUs and are frequently placed in areas not served by ETUs; if built rapidly enough and in sufficient quantity, CCCs will allow Ebola-related health measures to reach a larger proportion of the population. Staffing requirements for CCCs are frequently lower than for ETUs because CCCs are often designed such that basic patient needs such as food are provided for by friends and family of patients rather than by CCC staff. (It is customary in Liberia for friends and family to provide food for hospitalized patients.) Creation of CCCs in Liberia has been led by county health officials and nongovernmental organizations, and this local, community-based approach is intended to destigmatize Ebola, to encourage persons with illness to seek care rather than remain at home, and to facilitate contact tracing of exposed family members. This report describes one Liberian county's approach to establishing a CCC.
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Data Source
Authors
Logan,G., Vora,N.M., Nyensuah,T.G., Gasasira,A., Mott,J., Walke,H., Mahoney,F., Luce,R., Flannery,B., Centers for Disease Control and Prevention (CDC)
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Cross-country comparison of waterpipe use: nationally representative data from 13 low and middle-income countries from the Global Adult Tobacco Survey (GATS) 2014 Office on Smoking and Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Office on Smoking and Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; World Health Organization Regional Office for the Eastern M
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Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Sep
Volume
23
Issue
5
Start Page
419
Other Pages
427
Notes
LR: 20151119; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; JID: 9209612; 059QF0KO0R (Water); OID: NLM: PMC414541
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 23760609
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1136/tobaccocontrol-2012-050841 [doi]
Output Language
Unknown(0)
PMID
23760609
Abstract
OBJECTIVE: Evidence shows that smoking tobacco using a waterpipe is significantly associated with diseases. Despite this, waterpipe use seems to be increasing worldwide, though nationally representative data are not widely available. The Global Adult Tobacco Survey (GATS) provides an opportunity to measure various indicators of waterpipe use from nationally representative surveys. METHODS: Data were obtained for adults 15 years of age or older from 13 countries (Bangladesh, Brazil, China, Egypt, India, Mexico, Philippines, Russia, Thailand, Turkey, Ukraine, Uruguay and Vietnam) who completed GATS from 2008-2010. The GATS questionnaire collected data on current waterpipe use, including daily/less than daily prevalence and number of sessions per day/week. An optional waterpipe module measured former use, age of initiation, and level of consumption during a session. RESULTS: GATS was successful in producing nationally representative data on waterpipe use from 13 countries, many of which for the first time. The prevalence of waterpipe use among men was highest in Vietnam (13.0%) and Egypt (6.2%); among women, waterpipe use was highest in Russia (3.2%) and Ukraine (1.1%). While over 90% of adults in Ukraine thought smoking tobacco causes serious illness, only 31.4% thought smoking tobacco using a waterpipe causes serious illness. CONCLUSIONS: GATS data provide the ability to analyse waterpipe use within a country and across countries. Monitoring of waterpipe use at a national level will better enable countries to target tobacco control interventions such as education campaigns about the negative health effects of waterpipe use.
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Database
Publisher
Data Source
Authors
Morton,J., Song,Y., Fouad,H., Awa,F.E., Abou El Naga,R., Zhao,L., Palipudi,K., Asma,S., GATS Collaborative Group
Original/Translated Title
URL
Date of Electronic
20130611
PMCID
PMC4145417
Editors
Hookah use among adolescents in the United States: results of a national survey 2014 Department of Pediatrics, New York University School of Medicine, New York, NY;
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
16
Issue
2
Start Page
231
Other Pages
237
Notes
JID: 9815751; 2013/10/23 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 24154512
Language
eng
SubFile
Journal Article; IM
DOI
10.1093/ntr/ntt160 [doi]
Output Language
Unknown(0)
PMID
24154512
Abstract
INTRODUCTION: U.S. adolescents increasingly use alternative tobacco products (ATPs), including hookah. No study has previously assessed correlates of adolescent hookah use in a nationally representative sample. METHODS: Cross-sectional, nationally representative data of adolescents from the 2011 National Youth Tobacco Survey (NYTS) were used. Student demographics and their use of, exposure to, and beliefs about tobacco were examined as correlates of hookah use. RESULTS: Of adolescents nationwide, 7.3% reported ever trying hookah and 2.6% reported using hookah within the past month. Increasing age was associated with trying hookah, but not current hookah use. Sex was unassociated with hookah use. Asians were most likely to have tried hookah; Hispanics and those of another race reported greater current hookah use. Hookah use increased with perceived ease of access to and willingness to try tobacco. Students with a hookah user at home were more likely to have tried hookah and to currently use hookah. Current cigarette use was not associated with current hookah use (odds ratio [OR] = 1.3, 95% CI = 0.8-2.1), but was associated with trying hookah (OR = 1.5, 95% CI = 1.1-2.2). Non-cigarette tobacco use was associated with trying hookah (OR = 2.7, 95% CI = 2.1-3.5) and current hookah use (OR = 4.8, 95% CI = 2.7-8.7). CONCLUSIONS: A sizeable minority of U.S. adolescents use hookah, particularly those living with hookah users, those who use other ATPs, and those who perceive tobacco as easily accessible. Current cigarette use was not associated with current hookah use. Future studies assessing the dangers of hookah use and interventions to curb this emerging problem appear warranted.
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Database
Publisher
Data Source
Authors
Amrock,S.M., Gordon,T., Zelikoff,J.T., Weitzman,M.
Original/Translated Title
URL
Date of Electronic
20131023
PMCID
Editors
Effects of caloric restriction on nitrogen and carbon stable isotope ratios in adult rat bone 2014 Department of Anthropology, Box 117305, University of Florida, Gainesville, FL, 32611, USA; Department of Psychology, Box 112250, University of Florida, Gainesville, FL, 32611, USA.
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Print(0)
Ref Type
Journal Article
Periodical, Full
Rapid communications in mass spectrometry : RCM
Periodical, Abbrev.
Rapid Commun.Mass Spectrom.
Pub Date Free Form
15-Oct
Volume
28
Issue
19
Start Page
2065
Other Pages
2074
Notes
CI: Copyright (c) 2014; JID: 8802365; 0 (Carbon Isotopes); 0 (Hormones); 0 (Nitrogen Isotopes); 2014/06/23 [received]; 2014/07/21 [revised]; 2014/07/22 [accepted]; ppublish
Place of Publication
England
ISSN/ISBN
1097-0231; 0951-4198
Accession Number
PMID: 25156596
Language
eng
SubFile
Journal Article; IM
DOI
10.1002/rcm.6994 [doi]
Output Language
Unknown(0)
PMID
25156596
Abstract
RATIONALE: Stable isotope analysis is a valuable technique for dietary estimation in ecological and archaeological research, yet many variables can potentially affect tissue stable isotope signatures. Controlled feeding studies across a range of species have consistently demonstrated impacts of caloric restriction on tissue stable isotope ratios, but most have focused on juvenile, fasting, and/or starving individuals, and most have utilized soft tissues despite the importance of bone for paleodietary analyses. The goal of this study was to determine whether temporally defined, moderate food restriction could affect stable carbon and/or nitrogen isotope ratios in adult mammalian bone - a tissue that arguably reflects long-term dietary signals. METHODS: Adult rats fed a standard laboratory diet were restricted to 45% of ad libitum intakes for 3 or 6 months. Relevant anatomical and physiological parameters were measured to confirm that the restriction protocol resulted in significant nutritional stress and to provide independent data to facilitate interpretation of stable isotope ratios. Femoral bone delta(13)Ccollagen, delta(15)Ncollagen, and delta(13)Capatite values were determined by isotope ratio mass spectrometry. RESULTS: Calorie-restricted animals exhibited a small, yet significant enrichment in (15)Ncollagen compared with control animals, reflecting protein-calorie stress. While the delta(13)Ccollagen values did not differ, the delta(13)Capatite values revealed less enrichment in (13)C than in controls, reflecting catabolism of body fat. Independent anatomical and physiological data from these same individuals support these interpretations. CONCLUSIONS: Results indicate that moderate caloric restriction does not appreciably undermine broad interpretations of dietary signals in adult mammalian bone. Significant variability among individuals or groups, however, is best explained by marked differences in energy intake over variable timescales. An inverse relationship between the delta(13)Capatite and delta(15)Ncollagen values observed in this study indicates that a more robust pattern is expected with more severe or prolonged restriction and suggests this pattern may have utility as a marker of food deprivation in archaeological populations.
Descriptors
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Book Title
Database
Publisher
John Wiley & Sons, Ltd
Data Source
Authors
Robertson,K.L., Rowland,N.E., Krigbaum,J.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Tobacco product use among adults--United States, 2012-2013 2014
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
27-Jun
Volume
63
Issue
25
Start Page
542
Other Pages
547
Notes
LR: 20140819; JID: 7802429; EIN: MMWR Morb Mortal Wkly Rep. 2014 Jul 4;63(26):576; ppublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 24964880
Language
eng
SubFile
Journal Article; IM
DOI
mm6325a3 [pii]
Output Language
Unknown(0)
PMID
24964880
Abstract
Despite significant declines in cigarette smoking among U.S. adults over the past five decades, progress has slowed in recent years, and the prevalence of use of other tobacco products such as cigars and smokeless tobacco has not changed. Additionally, the prevalence of use of emerging products, including electronic cigarettes (e-cigarettes), has rapidly increased. This report provides the most recent national estimates of tobacco use among adults aged >/=18 years, using data from the 2012-2013 National Adult Tobacco Survey (NATS). The findings indicate that 21.3% of U.S. adults used a tobacco product every day or some days, and 25.2% used a tobacco product every day, some days, or rarely. Population-level interventions focused on the diversity of tobacco product use, including tobacco price increases, high-impact antitobacco mass media campaigns, comprehensive smoke-free laws, and enhanced access to help quitting, in conjunction with Food and Drug Administration (FDA) regulation of tobacco products, are critical to reducing tobacco-related diseases and deaths in the United States.
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Data Source
Authors
Agaku,I.T., King,B.A., Husten,C.G., Bunnell,R., Ambrose,B.K., Hu,S.S., Holder-Hayes,E., Day,H.R., Centers for Disease Control and Prevention (CDC)
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The use of allograft and recombinant human bone morphogenetic protein for instrumented atlantoaxial fusions 2014 Department of Neurological Surgery and The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, Florida, USA.; Department of Neurosurgery, University of Maryland, Baltimore, Maryland, USA.; Department of Neurological Surg
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
World neurosurgery
Periodical, Abbrev.
World Neurosurg.
Pub Date Free Form
Dec
Volume
82
Issue
6
Start Page
1369
Other Pages
1373
Notes
LR: 20160519; CI: Copyright (c) 2014; JID: 101528275; 0 (Bone Morphogenetic Protein 2); 0 (Recombinant Proteins); 0 (Transforming Growth Factor beta); 0 (recombinant human bone morphogenetic protein-2); CIN: World Neurosurg. 2014 Dec;82(6):1050-1. PMID: 2
Place of Publication
United States
ISSN/ISBN
1878-8769; 1878-8750
Accession Number
PMID: 23336983
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.wneu.2013.01.083 [doi]
Output Language
Unknown(0)
PMID
23336983
Abstract
BACKGROUND: Iliac crest autograft is the historic gold standard for bone grafting, but is associated with a significant patient morbidity. Fusion rates of C1-C2 up to 88.9% using allograft and 96.7% using autologous iliac crest bone graft can be achieved when combined with rigid screw fixation. We sought to determine our fusion rate when combining allograft with recombinant human bone morphogenetic protein-2 (rh-BMP2) and rigid screw fixation. METHODS: We reviewed our experience using allograft, bone morphogenetic protein (rh-BMP2) and screw fixation of C1-C2 in 52 patients and examined indications, surgical technique, fusion rates, and complications. In 28 patients, corticocancellous allograft pieces were laid along decorticated bone after a C2 neurectomy was performed. In 24 patients, unicortical iliac crest allograft was precision-cut to fit between the C1 lamina and C2 spinous processes. RESULTS: Fifty-two C1-C2 fusions were performed with allograft, rh-BMP2, and rigid screw fixation. There were 25 female and 27 male patients ranging in age from 6 to 92 years (mean, 65.8 years). Operative indications included trauma (56%), degenerative disease (21%), rheumatoid arthritis (15%), congenital anomalies (6%), and synovial cyst (2%). The mean follow-up was 23.9 +/- 2.1 months (range, 2-55 months). The mean dose of rh-BMP2 used for all patients was 4.5 mg (range, 2.2-12 mg). In patients who achieved sufficient follow-up, 100% achieved solid fusion: 45/50 Lenke A, 5/50 Lenke B. There were no known complications attributable to the use of rh-BMP2. CONCLUSIONS: The use of small doses of rh-BMP2 added to allograft in addition to rigid screw fixation is a safe and highly effective means of promoting a solid fusion of the atlantoaxial complex and spares the patient the morbidity of iliac crest harvest.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Hood,B., Hamilton,D.K., Smith,J.S., Dididze,M., Shaffrey,C., Levi,A.D.
Original/Translated Title
URL
Date of Electronic
20130119
PMCID
Editors
Determination of eight bisphenol diglycidyl ethers in water by solid phase extraction-high performance liquid chromatography-tandem mass spectrometry 2014
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Se pu = Chinese journal of chromatography / Zhongguo hua xue hui
Periodical, Abbrev.
Se Pu
Pub Date Free Form
Jul
Volume
32
Issue
7
Start Page
730
Other Pages
734
Notes
JID: 9424804; ppublish
Place of Publication
China
ISSN/ISBN
1000-8713; 1000-8713
Accession Number
PMID: 25255565
Language
chi
SubFile
English Abstract; Journal Article
DOI
Output Language
Unknown(0)
PMID
25255565
Abstract
A solid phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry (SPE-HPLC-MS/MS) method was developed for the determination of eight bisphenol diglycidyl ethers, including bisphenol A diglycidyl ether (BADGE), bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether (BADGE x HCl), bisphenol A bis (3-chloro-2-hydroxypropyl) ether (BADGE x 2HCl), bisphenol A (2, 3-dihydroxypropyl) glycidyl ether (BADGE x H2O), bisphenol A bis(2,3-dihydroxypropyl) ether (BADGE x 2H2O), bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether (BADGE x HCl x H2O), bisphenol F diglycidyl ether (BFDGE) and bisphenol F bis (3-chloro-2-hydroxypropyl) ether (BFDGE 2HCl) in water. A total of ten samples were collected from the leaching of the coatings for drinking water supply system. Then, 200 mL exposure water was preconcentrated on C18 solid-phase extraction cartridge. The eight compounds were analyzed by liquid chromatography-tandem mass spectrometry method on a C18 column by the gradient elution with methanol, water and 5 mmol/L ammonium acetate as mobile phases in the multiple reaction monitoring (MRM) scan mode. The external matrix standard solutions were used for the quantitative determination and the calibration curves of the eight compounds showed good linearity in the range of 0.007-5.00 microg/L with the correlation coefficients more than 0.999 0. The limits of quantification (LOQs) of the method were 7-91 ng/L. The spiked recoveries ranged from 79.1% to 101% with the relative standard deviations of 4.0% - 12%. The method is sensitive and accurate, and is applicable to the determination of bisphenol diglycidyl ethers in water.
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Book Title
Database
Publisher
Data Source
Authors
Zhang,H., Lin,S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Optimum pH for the determination of bisphenols and their corresponding diglycidyl ethers by gas chromatography-mass spectrometry. Migration kinetics of bisphenol A from polycarbonate glasses 2014 Department of Chemistry, Faculty of Sciences, University of Burgos, Plaza Misael Banuelos s/n, 09001 Burgos, Spain.; Department of Mathematics and Computation, Faculty of Sciences, University of Burgos, Plaza Misael Banuelos s/n, 09001 Burgos, Spain.; Dep
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
19-Sep
Volume
1360
Issue
Start Page
23
Other Pages
38
Notes
CI: Copyright (c) 2014; JID: 9318488; 0 (Benzhydryl Compounds); 0 (Ethers); 0 (Phenols); 0 (Polycarboxylate Cement); 0 (Polymers); 25766-59-0 (polycarbonate); MLT3645I99 (bisphenol A); OTO: NOTNLM; 2014/06/11 [received]; 2014/07/18 [revised]; 2014/07/21 [
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 25113873
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.chroma.2014.07.063 [doi]
Output Language
Unknown(0)
PMID
25113873
Abstract
This paper presents, on the one hand, the study of the influence of the pH of the medium on the determination of bisphenol F (BPF), bisphenol A (BPA) and their corresponding diglycidyl ethers (BFDGE and BADGE, respectively) by GC-MS after a solid-phase extraction step, using BPA-d16 as internal standard and Parallel Factor Analysis (PARAFAC) decomposition as a multi-way tool for the unequivocal identification and quantification of the four analytes. As the structure of both BFDGE and BADGE has two 2,3-epoxypropoxy groups that can undergo an acid- or base-catalyzed ring-opening via nucleophilic substitution reactions, several samples spiked with the four analytes were set to different pH values between 2 and 12. The best results were obtained in the pH region 8-10, being 9 the most suitable value. Coelution of interferents was overcome using the PARAFAC decomposition; otherwise, the presence of some analytes could not have been ensured according to the regulations currently in force. Secondly, the release of BPA from polycarbonate glasses into food simulant D1 (ethanol 50% (v/v)) over time was studied through seven migration tests and the differences found in this migration process with the incubation temperature (50 and 70 degrees C) were evaluated. A nonlinear regression was used to fit the experimental data following an exponential relation between the concentration of BPA transferred from every glass and the respective migration test. None of the quantities of BPA released exceeded the specific migration limit of 0.6mgkg(-1) laid down for this compound in the Commission Regulation (EU) No 10/2011, so the compliance of the glasses evaluated was ensured. The average recovery percentages of the four analytes at a fortification level of 800ngL(-1) ranged from 50.14 to 92.75%. The detection capability (CCbeta) of the method for BPA was 2.60mugL(-1) for n=2 replicates, with probabilities of false positive and false negative fixed at 0.05.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Oca,M.L., Sarabia,L.A., Herrero,A., Ortiz,M.C.
Original/Translated Title
URL
Date of Electronic
20140727
PMCID
Editors
Risk assessment of volatile organic compounds benzene, toluene, ethylbenzene, and xylene (BTEX) in consumer products 2014 a Division of Toxicology , College of Pharmacy, Sungkyunkwan University , Suwon , Gyeonggi-do , South Korea.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of toxicology and environmental health.Part A
Periodical, Abbrev.
J.Toxicol.Environ.Health A
Pub Date Free Form
Volume
77
Issue
22-24
Start Page
1502
Other Pages
1521
Notes
JID: 100960995; 0 (Benzene Derivatives); 0 (Volatile Organic Compounds); 0 (Xylenes); 3FPU23BG52 (Toluene); J64922108F (Benzene); L5I45M5G0O (ethylbenzene); ppublish
Place of Publication
England
ISSN/ISBN
1528-7394; 0098-4108
Accession Number
PMID: 25343298
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1080/15287394.2014.955905 [doi]
Output Language
Unknown(0)
PMID
25343298
Abstract
Exposure and risk assessment was performed by evaluating levels of volatile organic compounds (VOC) benzene, toluene, ethylbenzene, and xylene (BTEX) in 207 consumer products. The products were categorized into 30 different items, consisting of products of different brands. Samples were analyzed for BTEX by headspace-gas chromatography/mass spectrometry (headspace-GC/MS) with limit of detection (LOD) of 1 ppm. BTEX were detected in 59 consumer products from 18 item types. Benzene was detected in whiteout (ranging from not detected [ND] to 3170 ppm), glue (1486 ppm), oil-based ballpoint pens (47 ppm), and permanent (marking) pens (2 ppm). Toluene was detected in a leather cleaning product (6071 ppm), glue (5078 ppm), whiteout (1130 ppm), self-adhesive wallpaper (15-1012 ppm), shoe polish (806 ppm), permanent pen (609 ppm), wig adhesive (372 ppm), tapes (2-360 ppm), oil-based ballpoint pen (201 ppm), duplex wallpaper (12-52 ppm), shoes (27 ppm), and air freshener (13 ppm). High levels of ethylbenzene were detected in permanent pen (ND-345,065 ppm), shoe polish (ND-277,928 ppm), leather cleaner (42,223 ppm), whiteout (ND-2,770 ppm), and glue (ND-792 ppm). Xylene was detected in permanent pen (ND-285,132 ppm), shoe polish (ND-87,298 ppm), leather cleaner (12,266 ppm), glue (ND-3,124 ppm), and whiteout (ND-1,400 ppm). Exposure assessment showed that the exposure to ethylbenzene from permanent pens ranged from 0 to 3.11 mg/kg/d (men) and 0 to 3.75 mg/kg/d (women), while for xylene, the exposure ranges were 0-2.57 mg/kg/d and 0-3.1 mg/kg/d in men and women, respectively. The exposure of women to benzene from whiteout ranged from 0 to 0.00059 mg/kg/d. Hazard index (HI), defined as a ratio of exposure to reference dose (RfD), for ethylbenzene was 31.1 (3.11 mg/kg/d/0.1 mg/kg/d) and for xylene (2.57 mg/kg/d/0.2 mg/kg/d) was 12.85, exceeding 1 for both compounds. Cancer risk for benzene was calculated to be 3.2 x 10(-5) based on (0.00059 mg/kg/d x 0.055 mg/kg-d(-1), cancer potency factor), assuming that 100% of detected levels in some products such as permanent pens and whiteouts were exposed in a worst-case scenario. These data suggest that exposure to VOC via some consumer products exceeded the safe limits and needs to be reduced.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Lim,S.K., Shin,H.S., Yoon,K.S., Kwack,S.J., Um,Y.M., Hyeon,J.H., Kwak,H.M., Kim,J.Y., Kim,T.Y., Kim,Y.J., Roh,T.H., Lim,D.S., Shin,M.K., Choi,S.M., Kim,H.S., Lee,B.M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
In vitro activities of antifungal combinations against biofilms and planktonic forms of clinical Trichosporon asahii isolates 2014 Department of Dermatology, General Hospital of Beijing Military Command, Beijing, People's Republic of China.; Department of Dermatology, General Hospital of Beijing Military Command, Beijing, People's Republic of China.; Department of Dermatology, Genera
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
Dec
Volume
58
Issue
12
Start Page
7615
Other Pages
7616
Notes
LR: 20151029; JID: 0315061; 0 (Antifungal Agents); 0 (Drug Combinations); 0 (Echinocandins); 7XU7A7DROE (Amphotericin B); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole); OID: NLM: PMC4249521; 2014/09/22 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1098-6596; 0066-4804
Accession Number
PMID: 25246408
Language
eng
SubFile
Letter; Research Support, Non-U.S. Gov't; IM
DOI
10.1128/AAC.03817-14 [doi]
Output Language
Unknown(0)
PMID
25246408
Abstract
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Liao,Y., Yang,S., Cong,L., Lu,X., Ao,J., Yang,R.
Original/Translated Title
URL
Date of Electronic
20140922
PMCID
PMC4249521
Editors