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A newly identified susceptibility locus near FOXP1 modifies the association of gastroesophageal reflux with Barrett's esophagus 2015 Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Biostatistics, University of Washington, School of Public Health, Seattle, Washington. jdai@fredhutch.org tvaughan@u.washington.edu.; Division o
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Journal Article
Periodical, Full
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Periodical, Abbrev.
Cancer Epidemiol.Biomarkers Prev.
Pub Date Free Form
Nov
Volume
24
Issue
11
Start Page
1739
Other Pages
1747
Notes
LR: 20160715; CI: (c)2015; GR: K05 CA124911/CA/NCI NIH HHS/United States; GR: K05CA124911/CA/NCI NIH HHS/United States; GR: K24 DK100548/DK/NIDDK NIH HHS/United States; GR: P01 CA053996/CA/NCI NIH HHS/United States; GR: P01 CA091955/CA/NCI NIH HHS/United
Place of Publication
United States
ISSN/ISBN
1538-7755; 1055-9965
Accession Number
PMID: 26377193
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1158/1055-9965.EPI-15-0507 [doi]
Output Language
Unknown(0)
PMID
26377193
Abstract
BACKGROUND: Important risk factors for esophageal adenocarcinoma and its precursor, Barrett's esophagus, include gastroesophageal reflux disease, obesity, and cigarette smoking. Recently, genome-wide association studies have identified seven germline single-nucleotide polymorphisms (SNP) that are associated with risk of Barrett's esophagus and esophageal adenocarcinoma. Whether these genetic susceptibility loci modify previously identified exposure-disease associations is unclear. METHODS: We analyzed exposure and genotype data from the BEACON Consortium discovery phase GWAS, which included 1,516 esophageal adenocarcinoma case patients, 2,416 Barrett's esophagus case patients, and 2,187 control participants. We examined the seven newly identified susceptibility SNPs for interactions with body mass index, smoking status, and report of weekly heartburn or reflux. Logistic regression models were used to estimate ORs for these risk factors stratified by SNP genotype, separately for Barrett's esophagus and esophageal adenocarcinoma. RESULTS: The odds ratio for Barrett's esophagus associated with at least weekly heartburn or reflux varied significantly with the presence of at least one minor allele of rs2687201 (nominal P = 0.0005, FDR = 0.042). ORs (95% CIs) for weekly heartburn or reflux among participants with 0, 1, or 2 minor alleles of rs2687201 were 6.17 (4.91-7.56), 3.56 (2.85-4.44), and 3.97 (2.47-6.37), respectively. No statistically significant interactions were observed for smoking status and body mass index. CONCLUSION: Reflux symptoms are more strongly associated with Barrett's esophagus risk among persons homozygous for the major allele of rs2687201, which lies approximately 75 kb downstream of the transcription factor gene FOXP1. IMPACT: The novel gene-exposure interaction discovered in this study provides new insights into the etiology of esophageal adenocarcinoma.
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Book Title
Database
Publisher
American Association for Cancer Research
Data Source
Authors
Dai,J.Y., de Dieu Tapsoba,J., Buas,M.F., Onstad,L.E., Levine,D.M., Risch,H.A., Chow,W.H., Bernstein,L., Ye,W., Lagergren,J., Bird,N.C., Corley,D.A., Shaheen,N.J., Wu,A.H., Reid,B.J., Hardie,L.J., Whiteman,D.C., Vaughan,T.L.
Original/Translated Title
URL
Date of Electronic
20150916
PMCID
PMC4816532
Editors
Crystal structure of 4-chloro-N-[2-(piperidin-1-yl)eth-yl]benzamide monohydrate 2015 PG and Research Department of Physics, Queen Mary's College, Chennai-4, Tamilnadu, India.; Department of Chemistry, Madras Christian College, Chennai-59, India.; PG and Research Department of Physics, Queen Mary's College, Chennai-4, Tamilnadu, India.; PG
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Print(0)
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Journal Article
Periodical, Full
Acta crystallographica.Section E, Crystallographic communications
Periodical, Abbrev.
Acta Crystallogr.E.Crystallogr.Commun.
Pub Date Free Form
1-Jan
Volume
71
Issue
Pt 1
Start Page
o39
Other Pages
40
Notes
LR: 20150225; JID: 101648987; OID: NLM: PMC4331843; OTO: NOTNLM; 2015/01/01 [ecollection]; 2014/12/02 [received]; 2014/12/07 [accepted]; epublish
Place of Publication
England
ISSN/ISBN
2056-9890
Accession Number
PMID: 25705496
Language
eng
SubFile
Journal Article
DOI
10.1107/S2056989014026851 [doi]
Output Language
Unknown(0)
PMID
25705496
Abstract
In the title compound, C14H19ClN2O2.H2O, the piperdine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and that of the phenyl ring is 41.64 (1) degrees . In the crystal, mol-ecules are linked by O-Hcdots, three dots, centeredN, N-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredO hydrogen bonds involving the water mol-ecule, forming double-stranded chains propagating along [010].
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Database
Publisher
Data Source
Authors
Prathebha,K., Reuben Jonathan,D., Revathi,B.K., Sathya,S., Usha,G.
Original/Translated Title
URL
Date of Electronic
20150101
PMCID
PMC4331843
Editors
Controlling the last known cluster of Ebola virus disease - Liberia, January-February 2015 2015
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Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
15-May
Volume
64
Issue
18
Start Page
500
Other Pages
504
Notes
LR: 20160122; JID: 7802429; EIN: MMWR Morb Mortal Wkly Rep. 2015 Jul 31;64(18):806. Yaemsiri, Sirin [Added]; EIN: MMWR Morb Mortal Wkly Rep. 2015 Oct 23;64(41):1180. Cordier-Lasalle, Thierry [Corrected to Cordier-Lassalle, Thierry]. PMID: 26491830; ppubli
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 25974635
Language
eng
SubFile
Journal Article; IM
DOI
mm6418a5 [pii]
Output Language
Unknown(0)
PMID
25974635
Abstract
As one of the three West African countries highly affected by the 2014-2015 Ebola virus disease (Ebola) epidemic, Liberia reported approximately 10,000 cases. The Ebola epidemic in Liberia was marked by intense urban transmission, multiple community outbreaks with source cases occurring in patients coming from the urban areas, and outbreaks in health care facilities (HCFs). This report, based on data from routine case investigations and contact tracing, describes efforts to stop the last known chain of Ebola transmission in Liberia. The index patient became ill on December 29, 2014, and the last of 21 associated cases was in a patient admitted into an Ebola treatment unit (ETU) on February 18, 2015. The chain of transmission was stopped because of early detection of new cases; identification, monitoring, and support of contacts in acceptable settings; effective triage within the health care system; and rapid isolation of symptomatic contacts. In addition, a "sector" approach, which divided Montserrado County into geographic units, facilitated the ability of response teams to rapidly respond to community needs. In the final stages of the outbreak, intensive coordination among partners and engagement of community leaders were needed to stop transmission in densely populated Montserrado County. A companion report describes the efforts to enhance infection prevention and control efforts in HCFs. After February 19, no additional clusters of Ebola cases have been detected in Liberia. On May 9, the World Health Organization declared the end of the Ebola outbreak in Liberia.
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Data Source
Authors
Nyenswah,T., Fallah,M., Sieh,S., Kollie,K., Badio,M., Gray,A., Dilah,P., Shannon,M., Duwor,S., Ihekweazu,C., Cordier-Lassalle,T., Shinde,S.A., Hamblion,E., Davies-Wayne,G., Ratnesh,M., Dye,C., Yoder,J.S., McElroy,P., Hoots,B., Christie,A., Vertefeuille,J., Olsen,S.J., Laney,A.S., Neal,J.J., Yaemsiri,S., Navin,T.R., Coulter,S., Pordell,P., Lo,T., Kinkade,C., Mahoney,F., Centers for Disease Control and Prevention (CDC)
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Who is using e-cigarettes in Canada? Nationally representative data on the prevalence of e-cigarette use among Canadians 2015 Propel Centre for Population Health Impact, University of Waterloo, 200 University Ave. W., Waterloo, ON, Canada, N2L 3G1. Electronic address: jl3reid@uwaterloo.ca.; Propel Centre for Population Health Impact, University of Waterloo, 200 University Ave. W
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Print(0)
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Journal Article
Periodical, Full
Preventive medicine
Periodical, Abbrev.
Prev.Med.
Pub Date Free Form
Dec
Volume
81
Issue
Start Page
180
Other Pages
183
Notes
CI: Copyright (c) 2015; JID: 0322116; OTO: NOTNLM; 2015/05/28 [received]; 2015/08/27 [revised]; 2015/08/31 [accepted]; 2015/09/05 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1096-0260; 0091-7435
Accession Number
PMID: 26348453
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.ypmed.2015.08.019 [doi]
Output Language
Unknown(0)
PMID
26348453
Abstract
The current study examined prevalence and correlates of electronic cigarette (e-cigarette) use in the Canadian population, using data from the nationally representative 2013 Canadian Tobacco, Alcohol and Drugs Survey (n=14,565). Sociodemographic correlates of e-cigarette use (ever, and in the past 30 days) were examined using logistic regression models. Overall, 8.5% of Canadians aged 15 and older reported having ever tried an e-cigarette; 1.8% had used one in the past 30 days. E-cigarette use was particularly high among smokers and young people. Overall, prevalence did not differ between males and females, for ever (P=0.24) or past 30-day use (P=0.30). Smoking status was the strongest correlate of e-cigarette use (ever and in the past 30 days, P
Descriptors
Links
Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Reid,J.L., Rynard,V.L., Czoli,C.D., Hammond,D.
Original/Translated Title
URL
Date of Electronic
20150905
PMCID
Editors
Degradation of specific aromatic compounds migrating from PEX pipes into drinking water 2015 Department of Environmental Engineering, Technical University of Denmark, Miljoevej, Building 113, 2800 Kgs. Lyngby, Denmark. Electronic address: sury@env.dtu.dk.; Department of Environmental Engineering, Technical University of Denmark, Miljoevej, Buildi
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Print(0)
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Journal Article
Periodical, Full
Water research
Periodical, Abbrev.
Water Res.
Pub Date Free Form
15-Sep
Volume
81
Issue
Start Page
269
Other Pages
278
Notes
CI: Copyright (c) 2015; JID: 0105072; 0 (Drinking Water); 0 (Organic Chemicals); 0 (Water Pollutants, Chemical); 9002-88-4 (Polyethylene); OTO: NOTNLM; 2014/12/29 [received]; 2015/05/24 [revised]; 2015/05/27 [accepted]; 2015/05/29 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1879-2448; 0043-1354
Accession Number
PMID: 26074190
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.watres.2015.05.054 [doi]
Output Language
Unknown(0)
PMID
26074190
Abstract
Nine specific compounds identified to migrate from polyethylene (PE) and cross-linked polyethylene (PEX) to drinking water were investigated for their degradation in drinking water. Three sample types were studied: field samples (collected at consumer taps), PEX pipe water extractions, and water samples spiked with target compounds. Four compounds were quantified in field samples at concentrations of 0.15-8.0 mug/L. During PEX pipe water extraction 0.42 +/- 0.20 mg NVOC/L was released and five compounds quantified (0.5-6.1 mug/L). The degradation of these compounds was evaluated in PEX-pipe water extractions and spiked samples. 4-ethylphenol was degraded within 22 days. Eight compounds were, however, only partially degradable under abiotic and biotic conditions within the timeframe of the experiments (2-4 weeks). Neither inhibition nor co-metabolism was observed in the presence of acetate or PEX pipe derived NVOC. Furthermore, the degradation in drinking water from four different locations with three different water works was similar. In conclusion, eight out of the nine compounds studied would - if being released from the pipes - reach consumers with only minor concentration decrease during water distribution.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Ryssel,S.T., Arvin,E., Lutzhoft,H.C., Olsson,M.E., Prochazkova,Z., Albrechtsen,H.J.
Original/Translated Title
URL
Date of Electronic
20150529
PMCID
Editors
Risky behaviors, e-cigarette use and susceptibility of use among college students 2015 University at Buffalo, State University of New York, School of Public Health and Health Professions, Department of Community Health and Health Behavior, Buffalo, NY, USA. Electronic address: mls38@buffalo.edu.; University at Buffalo, State University of N
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Drug and alcohol dependence
Periodical, Abbrev.
Drug Alcohol Depend.
Pub Date Free Form
1-Apr
Volume
149
Issue
Start Page
25
Other Pages
30
Notes
CI: Copyright (c) 2015; JID: 7513587; OTO: NOTNLM; 2014/09/11 [received]; 2014/12/11 [revised]; 2015/01/02 [accepted]; 2015/01/24 [aheadofprint]; ppublish
Place of Publication
Ireland
ISSN/ISBN
1879-0046; 0376-8716
Accession Number
PMID: 25666362
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.drugalcdep.2015.01.001 [doi]
Output Language
Unknown(0)
PMID
25666362
Abstract
BACKGROUND: Since 2007, there has been a rise in the use of electronic cigarettes (e-cigarettes). The present study uses cross-sectional data (2013) to examine prevalence, correlates and susceptibility to e-cigarettes among young adults. METHODS: Data were collected using an Internet survey from a convenience sample of 1437, 18-23 year olds attending four colleges/universities in Upstate New York. Results were summarized using descriptive statistics; logistic regression models were analyzed to identify correlates of e-cigarette use and susceptibility to using e-cigarettes. RESULTS: Nearly all respondents (95.5%) reported awareness of e-cigarettes; 29.9% were ever users and 14.9% were current users. Younger students, males, non-Hispanic Whites, respondents reporting average/below average school ability, ever smokers and experimenters of tobacco cigarettes, and those with lower perceptions of harm regarding e-cigarettes demonstrated higher odds of ever use or current use. Risky behaviors (i.e., tobacco, marijuana or alcohol use) were associated with using e-cigarettes. Among never e-cigarette users, individuals involved in risky behaviors or, with lower harm perceptions for e-cigarettes, were more susceptible to future e-cigarette use. CONCLUSIONS: More e-cigarette users report use of another nicotine product besides e-cigarettes as the first nicotine product used; this should be considered when examining whether e-cigarette use is related to cigarette susceptibility. Involvement in risky behaviors is related to e-cigarette use and susceptibility to e-cigarette use. Among college students, e-cigarette use is more likely to occur in those who have also used other tobacco products, marijuana, and/or alcohol.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ireland Ltd
Data Source
Authors
Saddleson,M.L., Kozlowski,L.T., Giovino,G.A., Hawk,L.W., Murphy,J.M., MacLean,M.G., Goniewicz,M.L., Homish,G.G., Wrotniak,B.H., Mahoney,M.C.
Original/Translated Title
URL
Date of Electronic
20150124
PMCID
Editors
Short- and medium-term efficacy of a Web-based computer-tailored nutrition education intervention for adults including cognitive and environmental feedback: randomized controlled trial 2015 Maastricht University, Department of Health Promotion, School for Public Health and Primary Care (CAPHRI), Maastricht, Netherlands. linda.springvloet@maastrichtuniversity.nl.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of medical Internet research
Periodical, Abbrev.
J.Med.Internet Res.
Pub Date Free Form
19-Jan
Volume
17
Issue
1
Start Page
e23
Other Pages
Notes
LR: 20151119; NTR/NTR3396; JID: 100959882; OID: NLM: PMC4319071; OTO: NOTNLM; 2014/09/03 [received]; 2014/12/10 [accepted]; 2014/11/12 [revised]; epublish
Place of Publication
Canada
ISSN/ISBN
1438-8871; 1438-8871
Accession Number
PMID: 25599828
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM
DOI
10.2196/jmir.3837 [doi]
Output Language
Unknown(0)
PMID
25599828
Abstract
BACKGROUND: Web-based, computer-tailored nutrition education interventions can be effective in modifying self-reported dietary behaviors. Traditional computer-tailored programs primarily targeted individual cognitions (knowledge, awareness, attitude, self-efficacy). Tailoring on additional variables such as self-regulation processes and environmental-level factors (the home food environment arrangement and perception of availability and prices of healthy food products in supermarkets) may improve efficacy and effect sizes (ES) of Web-based computer-tailored nutrition education interventions. OBJECTIVE: This study evaluated the short- and medium-term efficacy and educational differences in efficacy of a cognitive and environmental feedback version of a Web-based computer-tailored nutrition education intervention on self-reported fruit, vegetable, high-energy snack, and saturated fat intake compared to generic nutrition information in the total sample and among participants who did not comply with dietary guidelines (the risk groups). METHODS: A randomized controlled trial was conducted with a basic (tailored intervention targeting individual cognition and self-regulation processes; n=456), plus (basic intervention additionally targeting environmental-level factors; n=459), and control (generic nutrition information; n=434) group. Participants were recruited from the general population and randomly assigned to a study group. Self-reported fruit, vegetable, high-energy snack, and saturated fat intake were assessed at baseline and at 1- (T1) and 4-months (T2) postintervention using online questionnaires. Linear mixed model analyses examined group differences in change over time. Educational differences were examined with groupxtimexeducation interaction terms. RESULTS: In the total sample, the basic (T1: ES=-0.30; T2: ES=-0.18) and plus intervention groups (T1: ES=-0.29; T2: ES=-0.27) had larger decreases in high-energy snack intake than the control group. The basic version resulted in a larger decrease in saturated fat intake than the control intervention (T1: ES=-0.19; T2: ES=-0.17). In the risk groups, the basic version caused larger decreases in fat (T1: ES=-0.28; T2: ES=-0.28) and high-energy snack intake (T1: ES=-0.34; T2: ES=-0.20) than the control intervention. The plus version resulted in a larger increase in fruit (T1: ES=0.25; T2: ES=0.37) and a larger decrease in high-energy snack intake (T1: ES=-0.38; T2: ES=-0.32) than the control intervention. For high-energy snack intake, educational differences were found. Stratified analyses showed that the plus version was most effective for high-educated participants. CONCLUSIONS: Both intervention versions were more effective in improving some of the self-reported dietary behaviors than generic nutrition information, especially in the risk groups, among both higher- and lower-educated participants. For fruit intake, only the plus version was more effective than providing generic nutrition information. Although feasible, incorporating environmental-level information is time-consuming. Therefore, the basic version may be more feasible for further implementation, although inclusion of feedback on the arrangement of the home food environment and on availability and prices may be considered for fruit and, for high-educated people, for high-energy snack intake. TRIAL REGISTRATION: Netherlands Trial Registry NTR3396; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=3396 (Archived by WebCite at http://www.webcitation.org/6VNZbdL6w).
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Springvloet,L., Lechner,L., de Vries,H., Candel,M.J., Oenema,A.
Original/Translated Title
URL
Date of Electronic
20150119
PMCID
PMC4319071
Editors
An observation of venous gas emboli in divers and susceptibility to decompression sickness 2015 Fremantle Hyperbaric Unit, Fremantle Hospital, Alma Street, PO Box 480, WA 6959, Australia, Phone: +61-(0)8-9431-2233, E-mail: ian.gawthrope@health.wa.gov.au.; The University of Notre Dame, Fremantle, Western Australia.; The University of Notre Dame, Frem
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Print(0)
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Journal Article
Periodical, Full
Diving and hyperbaric medicine
Periodical, Abbrev.
Diving.Hyperb.Med.
Pub Date Free Form
Mar
Volume
45
Issue
1
Start Page
25
Other Pages
29
Notes
JID: 101282742; OTO: NOTNLM; 2014/12/24 [received]; 2014/12/28 [accepted]; ppublish
Place of Publication
Australia
ISSN/ISBN
1833-3516; 1833-3516
Accession Number
PMID: 25964035
Language
eng
SubFile
Journal Article; Observational Study; IM
DOI
Output Language
Unknown(0)
PMID
25964035
Abstract
INTRODUCTION: Decompression sickness (DCS) results from the formation of bubbles within the tissues and blood in response to a reduction in environmental pressure. Venous gas emboli (VGE) are common after diving and are usually only present in small numbers. Greater VGE numbers are an indication of decompression stress, and can be reliably detected using ultrasound imaging. AIM: To examine the relationship between production of VGE following a routine dive and the risk of DCS. METHODS: A matched population of divers with and without a history of DCS were monitored for the production of VGE at 15-minute intervals using ultrasound, following a 405 kPa air dive in a hyperbaric chamber using the DCIEM air decompression table. VGE production was graded using a validated grading system and the data analysed to compare maximum VGE grade and duration of VGE formation. RESULTS: Eleven divers with a history of DCS were compared with 13 divers with no history of DCS. Divers with a history of DCS demonstrated both a higher maximum grade (P=0.04) and longer duration (P=0.002) of VGE production compared to divers without a history of DCS. CONCLUSION: Higher maximum VGE grades and longer durations of VGE following decompression were associated with a history of DCS and, in particular, musculoskeletal DCS. Although the exact mechanism of DCS remains poorly understood, our data suggest some individuals are inherently more prone to develop VGE, increasing the probability of DCS. Modification of diving practices in those with high VGE grades could potentially decrease DCS risk in these individuals.
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Database
Publisher
Data Source
Authors
Gawthrope,I.C., Summers,M., Macey,D.J., Playford,D.A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Tripling use of electronic cigarettes among New Zealand adolescents between 2012 and 2014 2015 Research and Evaluation, Health Promotion Agency, Wellington, New Zealand. Electronic address: j.white@hpa.org.nz.; Research and Evaluation, Health Promotion Agency, Wellington, New Zealand.; Research and Evaluation, Health Promotion Agency, Wellington, N
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Print(0)
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Journal Article
Periodical, Full
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Periodical, Abbrev.
J.Adolesc.Health
Pub Date Free Form
May
Volume
56
Issue
5
Start Page
522
Other Pages
528
Notes
CI: Copyright (c) 2015; JID: 9102136; OTO: NOTNLM; 2014/10/14 [received]; 2015/01/28 [revised]; 2015/01/28 [accepted]; ppublish
Place of Publication
United States
ISSN/ISBN
1879-1972; 1054-139X
Accession Number
PMID: 25907651
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.jadohealth.2015.01.022 [doi]
Output Language
Unknown(0)
PMID
25907651
Abstract
PURPOSE: Use of electronic cigarettes (e-cigarettes) among adults has flourished in recent years. However, little is known about their use among adolescents. This article reports on data collected from a New Zealand national youth tobacco use survey in 2012 and 2014. METHODS: The Youth Insights Survey is a biennial self-complete survey of Year 10 students (predominately aged 14-15 years), with a sample size of 3,127 in 2012 and 2,919 in 2014. Ever-use of e-cigarettes was self-reported by participants in both years, and in 2014, e-cigarette ever-users also reported their reasons for first trying e-cigarettes. RESULTS: The rate of e-cigarette ever-use tripled from 7.0% in 2012 to 20.0% in 2014. After adjusting for sociodemographic variables, smoking status (including susceptibility), and other factors associated with tobacco smoking uptake, e-cigarette ever-use was associated with gender, smoking status, close friends' smoking behavior, and risky substance use. Among smokers, desire for a cigarette, quit intention, or past-year quit attempts did not predict e-cigarette ever-use. Irrespective of smoking status, curiosity was the most commonly cited reason for trying e-cigarettes. CONCLUSIONS: In 2014, one in five 14- to 15-year-olds had used e-cigarettes. Our data suggest that for adolescent smokers, cessation was not the main reason for trying e-cigarettes. Instead, most adolescents (smokers and nonsmokers) tried e-cigarettes out of curiosity. Our findings signal a need to continue monitoring the uptake of e-cigarettes among adolescents, including both experimental and long-term use. Controlling access and exposure to e-cigarettes among this young age group is also required.
Descriptors
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Book Title
Database
Publisher
Society for Adolescent Health and Medicine. Published by Elsevier Inc
Data Source
Authors
White,J., Li,J., Newcombe,R., Walton,D.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Overlap of symptoms of gastroesophageal reflux disease, dyspepsia and irritable bowel syndrome in the general population 2015 Research Unit of General Practice, Institute of Public Health, University of Southern Denmark , Odense , Denmark.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Scandinavian Journal of Gastroenterology
Periodical, Abbrev.
Scand.J.Gastroenterol.
Pub Date Free Form
Feb
Volume
50
Issue
2
Start Page
162
Other Pages
169
Notes
LR: 20151119; JID: 0060105; OTO: NOTNLM; 2014/12/19 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1502-7708; 0036-5521
Accession Number
PMID: 25525975
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.3109/00365521.2014.983157 [doi]
Output Language
Unknown(0)
PMID
25525975
Abstract
INTRODUCTION: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common functional gastrointestinal conditions with significant impact on the daily lives of individuals. The objective was to investigate the prevalence and overlap of the three conditions in a Western general population. MATERIAL AND METHODS: A nationwide study of 100,000 individuals 20 years and above, randomly selected in the general population. A web-based questionnaire survey formed the basis of this study. Questions regarding FD and IBS were extracted from the ROME III adult questionnaire. Questions regarding GERD were developed based on the Montreal definition. Prevalence estimates for GERD, FD IBS were calculated in total and for each sex separately and for four age groups. A Venn diagram was constructed, illustrating the overlap between the three conditions. RESULTS: The overall response rate was 52.2%. The prevalence of GERD, FD and IBS was 11.2%, 7.7% and 10.5%, respectively, and overlap between two or three of these conditions was seen among 6.5% of the respondents. Among individuals meeting the criteria of one or more of the conditions GERD, FD and IBS, 30.7% had overlap between two or all three conditions. CONCLUSION: GERD, FD and IBS are common conditions in the general population and the overlap between these conditions is also quite common. When diagnosing patients with GERD, FD and IBS, physicians should keep in mind that these patients could be suffering from more than one of these conditions.
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Book Title
Database
Publisher
Data Source
Authors
Rasmussen,S., Jensen,T.H., Henriksen,S.L., Haastrup,P.F., Larsen,P.V., Sondergaard,J., Jarbol,D.E.
Original/Translated Title
URL
Date of Electronic
20141219
PMCID
Editors