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Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA 2004 Departamento de Ciencias Farmaceuticas, Centro de Ciencias da Saude, Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB, Brazil. leoniab@uol.com.br
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Biological & pharmaceutical bulletin
Periodical, Abbrev.
Biol.Pharm.Bull.
Pub Date Free Form
Mar
Volume
27
Issue
3
Start Page
328
Other Pages
332
Notes
LR: 20131121; JID: 9311984; 0 (2-Pyridinylmethylsulfinylbenzimidazoles); 0 (Anti-Ulcer Agents); 0 (Plant Extracts); 0 (Prostaglandins); 004F72P8F4 (Bethanechol); 0K5C5T2QPG (Lansoprazole); 3K9958V90M (Ethanol); 80061L1WGD (Cimetidine); KG60484QX9 (Omepraz
Place of Publication
Japan
ISSN/ISBN
0918-6158; 0918-6158
Accession Number
PMID: 14993797
Language
eng
SubFile
Comparative Study; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
14993797
Abstract
Syngonanthus arthrotrichus SILVEIRA, popularly known as "sempre-vivas mini-saia," is found in mountains of the Espinhaco range in the Brazilian states of Bahia and Minas Gerais. Extracts of this species contain several constituents, including flavonoids which may have antiulcerogenic activity. An ethanolic extract (EEOH), and flavonoid-rich (FRF) and flavonoid-deficient (FDF) fractions obtained from the scapes of S. arthrotrichus were investigated for their ability to prevent ulceration of the gastric mucosa in mice and rats. In the ethanol/HCl-induced ulcer model, lansoprazole (30 mg/kg), EEOH (50, 100, 250 mg/kg) given orally protected the gastric mucosal against injury in mice by 79%, 78%, 73%, and 64% respectively. In the ethanol-induced gastric ulcer model in rats, the lansoprazole (30 mg/kg), FRF and FDF (100 mg/kg) significantly protected the gastric mucosal of rats by 65%, 38% and 25% respectively when compared with the negative control group. In indomethacin/bethanechol-induced gastric ulcers, cimetidine (100 mg/kg) and the EEOH (100, 250 mg/kg) inhibited gastric ulcer formation by 73%, 55% and 32% respectively. In this exactly model other treatments as cimetidine, FRF and FDF (100 mg/kg) each caused 54%, 36% and 45% inhibition, respectively. In the stress-induced gastric ulcer model, cimetidine (100 mg/kg) and the EEOH (50, 100, 250 mg/kg), inhibited gastric ulcer formation by 63%, 73%, 68% and 69% respectively. In the same model, cimetidine, FRF and FDF (100 mg/kg) significantly protected the gastric mucosal of the mice by 60%, 51% and 47% when compared to the control group. In pylorus-ligated mice, cimetidine (positive control) and FRF significantly decreased gastric acid secretion, increased gastric pH and reduced the acid output when compared to the negative control. FDF had no significant effect on these parameters. The protection provided by FRF probably involved an antisecretory mechanism mediated by flavonoids which were absent in FDF. The amount of adherent mucous in the stomach contents was also evaluated with the treatments carbenoxolone (200 mg/kg), FRF and FDF (100 mg/kg) treatment. Each treatments significantly increased the amount of adherent mucous in the gastric juice (8.67+/-1.73, 3.35+/-1.59, 2.1+/-0.41 mg/g of wet tissue, respectively) compared to the control group, indicating a cytoprotective action on the gastric mucosa. Treatment with FRF plus indomethacin and FDF plus indomethacin reduced the prostaglandin biosyntesis (13.6+/-6.5, 27+/-5.5 pg/well) by the mucosa, indicating that the cytoprotective action on the gastric mucosa was not related to the level of prostaglandins. Only FDF (38+/-17 pg/well) maintained the level of prostaglandins and guaranteed the integrity of the mucosa. The results indicate that the EEOH, FRF and FDF have antisecretory and cytoprotective actions, that may be related to the presence of luteoline in the extract and active fractions.
Descriptors
2-Pyridinylmethylsulfinylbenzimidazoles, Animals, Anti-Ulcer Agents/chemistry/pharmacology/therapeutic use, Bethanechol, Cimetidine/therapeutic use, Disease Models, Animal, Eriocaulaceae/chemistry, Ethanol, Gastric Juice/secretion, Gastrointestinal Contents/chemistry, Hydrogen-Ion Concentration, Indomethacin, Lansoprazole, Male, Mice, Mucus/chemistry, Omeprazole/analogs & derivatives/therapeutic use, Phytotherapy, Plant Extracts/chemistry/pharmacology/therapeutic use, Prostaglandins/biosynthesis, Rats, Rats, Wistar, Stomach Ulcer/drug therapy/etiology/physiopathology, Stress, Psychological/complications
Links
Book Title
Database
Publisher
Data Source
Authors
Batista,L. M., de Almeida,A. B., de Pietro Magri,L., Toma,W., Calvo,T. R., Vilegas,W., Souza Brito,A. R.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Knowledge of and attitudes towards tobacco control among smoking and non-smoking physicians in 2 Gulf Arab states 2004
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Saudi Med J
Periodical, Abbrev.
Saudi Med.J.
Pub Date Free Form
Volume
25
Issue
5
Start Page
585
Other Pages
91
Notes
ID: 15138525
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
OBJECTIVE: The global health professional survey is a project organized by the World Health Organization, to determine the smoking habits, knowledge and attitude towards tobacco control of health professionals in several countries around the world. This paper presents data from Kuwait and Bahrain. METHODS: The survey period was between May 2000 and March 2001. A questionnaire was distributed to all physicians in Bahrain and to a random sample from Kuwait. The responses to knowledge and attitude questions were on a scale of 1-5, (1 strongly agree, 2 agree, 3 unsure, 4 disagree and 5 strongly disagree). RESULTS: Four hundred and seventy physicians from Bahrain and 1095 from Kuwait completed the questionnaire. The prevalence of cigarette smoking in Kuwait was: current smokers 18.4%, previous smokers 15.8%, Bahrain 14.6% and 14.3%. The prevalence of shisha smoking was 12% and 6.4% for Kuwait and Bahrain, (p=0.004). The mean scores of agreement with the association between passive smoking and lung diseases, lower respiratory tract infections in children were 1.6, 1.7 and 1.8, 1.9 for non smoking physicians and smoking physicians (P<0.01). The mean scores of agreement with the following policies: large health warning on cigarette packages, complete ban on tobacco advertisement and an increase in the price of cigarette were 1.3, 1.4, 1.7 and 1.7, 1.7, 2.5 for smoking and non-smoking physicians (p<0.01). CONCLUSION: Smoking physicians have less knowledge and less favorable attitude towards tobacco control compared to non-smokers. There was no difference in the prevalence of cigarette smoking between Kuwait and Bahrain, but the prevalence of shisha smoking was higher in Kuwait.
Descriptors
Attitude of Health Personnel, Health Knowledge, Attitudes, Practice, Physicians/statistics & numerical data, Smoking Cessation, Smoking/epidemiology, Adult, Bahrain/epidemiology, Cross-Cultural Comparison, Cross-Sectional Studies, Female, Health Surveys, Humans, Kuwait/epidemiology, Male, Middle Aged, Physicians/psychology, Sampling Studies, Smoking/adverse effects, Smoking/prevention & control, Smoking Cessation/psychology
Links
http://pesquisa.bvsalud.org/ghl/resource/en/mdl-15138525
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Behbehani,Nasser N., Hamadeh,Randah R., Macklai,Nejma S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Prediction equations for pulmonary function values in healthy young Iranians aged 8-18 years 2004 Department of Physiology, Ghaem Medical Centre, Mashhad University of Medical Sciences, Mashhad, Iran. mhboskabady@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Respirology (Carlton, Vic.)
Periodical, Abbrev.
Respirology
Pub Date Free Form
Nov
Volume
9
Issue
4
Start Page
535
Other Pages
542
Notes
LR: 20061115; JID: 9616368; ppublish
Place of Publication
Australia
ISSN/ISBN
1323-7799; 1323-7799
Accession Number
PMID: 15612967
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Validation Studies; IM
DOI
RES623 [pii]
Output Language
Unknown(0)
PMID
15612967
Abstract
OBJECTIVE: Pulmonary function test (PFT) variables are dependent on height, age and gender. In addition, there is evidence of PFT variation in different ethnic groups. Prediction equations for PFT from a healthy, non-smoking, urban young population in the city of Mashhad (north-east Iran) have been derived. METHODOLOGY: Prediction equations for normal pulmonary function were derived from 336 healthy, non-smoking subjects, including 187 males (height 103-188.5 cm) and 149 females (height 104-183 cm) aged 8-18 years. The subjects underwent measurement of spirometric flow and volume. The following variables were measured: FVC, FEV1, maximal mid-expiratory flow (MMEF), PEF, maximal expiratory flow at 75, 50 and 25% of the FVC (MEF75, MEF50, and MEF25, respectively), tidal volume (VT), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), inspiratory capacity (IC), and vital capacity (VC). Regression analysis using height and age as independent variables was applied to provide predicted values for both genders. RESULTS: There were positive correlations for each pulmonary function variable with height and age. The largest positive correlations were found for FEV1 with height and age, in both genders. Comparison of PFT variables derived from the equations obtained in the present study showed significant differences to those calculated from several previously published equations (P < 0.001 for most variables). For example, the values of FVC and FEV1 derived from the equations obtained in the present study were 2.83 +/- 0.99 and 2.50 +/- 0.89 for males, and 2.41 +/- 0.54 and 2.19 +/- 0.53 for females, while the values derived from the equations of the European Community for Steel and Coal study were 3.12 +/- 1.06 and 2.62 +/- 0.89 for males and 2.79 +/- 0.67 and 3.35 +/- 0.57 for females, respectively. CONCLUSIONS: A set of PFT reference values and prediction equations for both genders has been derived using a relatively large, healthy, non-smoking Iranian young population, and has generated results that differ from several other prediction equations.
Descriptors
Adolescent, Age Factors, Body Height, Child, Female, Humans, Iran, Lung/physiology, Male, Predictive Value of Tests, Reference Values, Regression Analysis, Reproducibility of Results, Respiratory Function Tests/standards, Sex Factors, Urban Population
Links
Book Title
Database
Publisher
Data Source
Authors
Boskabady,M. H., Tashakory,A., Mazloom,R., Ghamami,G.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Symptoms, acid exposure and motility in patients with Barrett&#39;s esophagus 2004 Faculty of Medicine and Dentistry, University of Western Ontario, London, Ont.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Canadian journal of surgery.Journal canadien de chirurgie
Periodical, Abbrev.
Can.J.Surg.
Pub Date Free Form
Feb
Volume
47
Issue
1
Start Page
47
Other Pages
51
Notes
LR: 20140609; JID: 0372715; OID: NLM: PMC3211802; ppublish
Place of Publication
Canada
ISSN/ISBN
0008-428X; 0008-428X
Accession Number
PMID: 14997925
Language
eng
SubFile
Comparative Study; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
14997925
Abstract
INTRODUCTION: Barrett's esophagus, a syndrome in which the squamous mucosa that normally lines the distal esophagus is replaced with columnar epithelium, is found in a small percentage of patients presenting with gastroesophageal reflux disease (GERD). The columnar epithelium may be protective, guarding people afflicted with Barrett's esophagus from experiencing symptoms related to acid reflux. The purpose of this study was to investigate whether people with Barrett's esophagus subjectively experience fewer symptoms or symptoms of decreased severity, despite sustaining greater acid exposure, than those with GERD but without Barrett's syndrome. METHODS: We conducted a chart review of patients with GERD. Criteria for inclusion in the study were esophagogastroscopy, motility testing and a 24-hour pH study. Fifty-eight patients (29 men, 29 women) fulfilled these criteria. The diagnosis of GERD was based on an abnormal 24-hour pH study (DeMeester score). Of these 58 patients, 21 (14 men, 7 women) were found to have histologically confirmed Barrett's esophagus. A questionnaire to assess the key symptoms of GERD was administered, with a severity score ranging from 0 to 3 (3 being the most severe) for each symptom. RESULTS: Patients with Barrett's esophagus experienced symptoms significantly less severe (p 5 min) of acid exposure (p = 0.033) and an increased percentage of time when their pH was less than 4. Patients with Barrett's esophagus had decreased resting lower esophageal sphincter tone, and number and amplitude of peristaltic contractions. CONCLUSIONS: For patients with Barrett's esophagus, the columnar epithelium may serve a protective function in guarding against symptoms of acid reflux. This has implications for the diagnosis and management of this condition.
Descriptors
Adult, Age Distribution, Aged, Barrett Esophagus/epidemiology/pathology, Biopsy, Needle, Cohort Studies, Comorbidity, Esophagoscopy, Esophagus/physiology, Female, Gastric Acidity Determination, Gastroesophageal Reflux/epidemiology/pathology, Humans, Hydrogen-Ion Concentration, Immunohistochemistry, Incidence, Male, Manometry, Middle Aged, Peristalsis, Probability, Risk Assessment, Severity of Illness Index, Sex Distribution
Links
Book Title
Database
Publisher
Data Source
Authors
Brandt,M. G., Darling,G. E., Miller,L.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC3211802
Editors
Analysis of polycyclic aromatic hydrocarbons in contaminated soil by Curie point pyrolysis coupled to gas chromatography-mass spectrometry, an alternative to conventional methods 2004 University Aix-Marseille III, Avenue Escadrille Normandie Niemens, Marseille, France.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
13-Feb
Volume
1026
Issue
2-Jan
Start Page
223
Other Pages
229
Notes
LR: 20090115; JID: 9318488; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Soil); 0 (Soil Pollutants); ppublish
Place of Publication
Netherlands
ISSN/ISBN
0021-9673; 0021-9673
Accession Number
PMID: 14763749
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
14763749
Abstract
Curie point pyrolysis gas chromatography-mass spectrometry (Py-GC-MS) has been compared with classical extraction procedures (Soxhlet, sonication, KOH digestion, microwave-assisted) followed by GC-MS analysis for the determination of polycyclic aromatic hydrocarbons (PAHs) in contaminated soil. In each case, the efficiency of the technique was examined for 16 PAHs included in the US Environmental Protection Agency Priority Pollutant List. The results indicate that the recovery of PAHs is dependent on the extraction technique. The highest recoveries of PAHs were obtained with Curie point pyrolysis and KOH digestion. Py-GC-MS appeared to be interesting alternative method for the determination of PAHs in contaminated soil. The results were validated by certified soil (CRM 104) analysis.
Descriptors
Gas Chromatography-Mass Spectrometry/methods, Polycyclic Hydrocarbons, Aromatic/analysis/isolation & purification, Reference Standards, Soil/analysis, Soil Pollutants/analysis/isolation & purification, United States, United States Environmental Protection Agency
Links
Book Title
Database
Publisher
Data Source
Authors
Buco,S., Moragues,M., Doumenq,P., Noor,A., Mille,G.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Determination of tar, nicotine, and carbon monoxide yields in the mainstream smoke of selected international cigarettes 2004 National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Mar
Volume
13
Issue
1
Start Page
45
Other Pages
51
Notes
LR: 20151119; JID: 9209612; 0 (Air Pollutants); 0 (Smoke); 0 (Tars); 6M3C89ZY6R (Nicotine); 7U1EE4V452 (Carbon Monoxide); OID: NLM: PMC1747810; ppublish
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 14985595
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.; IM
DOI
Output Language
Unknown(0)
PMID
14985595
Abstract
OBJECTIVE: Survey of nicotine, tar, and carbon monoxide (CO) smoke deliveries from 77 cigarette brands purchased in 35 countries was conducted using a standardised machine smoking method. The goal of this study was to determine regional variations and differences in the tar, nicotine, and CO smoke yields of a cigarette brand manufactured by a leading transnational corporation and of non-US locally popular cigarette brands. DESIGN: The majority of the cigarettes were purchased in each of the participating countries by delegate members of the World Health Organization and forwarded to the Centers for Disease Control and Prevention for analysis. Smoke deliveries were determined using a standardised smoking machine method and subsequent gravimetric and gas chromatography analysis. RESULTS: The smoke deliveries varied widely. Mainstream smoke deliveries varied from 6.8 to 21.6 mg tar/cigarette, 0.5 to 1.6 mg nicotine/cigarette, and 5.9 to 17.4 mg CO/cigarette. In addition to the smoke deliveries, the cigarettes were examined to determine physical parameters such as filter composition, length, and ventilation levels. CONCLUSION: Analysis of the smoke deliveries suggested that cigarettes from the Eastern Mediterranean, Southeast Asia, and Western Pacific WHO regions tended to have higher tar, nicotine, and CO smoke deliveries than did brands from the European, American, or African WHO regions surveyed.
Descriptors
Air Pollutants/analysis, Carbon Monoxide/analysis, Nicotine/analysis, Smoke/analysis, Tars/analysis, Tobacco
Links
Book Title
Database
Publisher
Data Source
Authors
Calafat,A. M., Polzin,G. M., Saylor,J., Richter,P., Ashley,D. L., Watson,C. H.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC1747810
Editors
Diversity of lactic acid bacteria isolated from AOC Salers cheese 2004 Institut National de Recherche Agronomique, Unite de Recherches Fromageres, Aurillac, France. callon@clermont.inra.fr
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of dairy research
Periodical, Abbrev.
J.Dairy Res.
Pub Date Free Form
May
Volume
71
Issue
2
Start Page
231
Other Pages
244
Notes
LR: 20061115; JID: 2985125R; 0 (DNA, Bacterial); ppublish
Place of Publication
England
ISSN/ISBN
0022-0299; 0022-0299
Accession Number
PMID: 15190953
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
Output Language
Unknown(0)
PMID
15190953
Abstract
The objective of this work was to describe the diversity of lactic acid bacteria in traditional raw milk Salers cheeses at the species and strain levels. The characterization of 381 strains isolated during ripening and various strain collections was investigated using physiological analysis and molecular techniques: Rep-PCR, species and genus specific amplifications and the sequence analysis of 16S rDNA for strain typing and taxonomic identification. The strains belonged to Lactobacillus plantarum, Lactobacillus paracasei, Lactococcus lactis, Lactococcus garviae, Enterococcus faecalis, Enterococcus faecium, Leuconostoc mesenteroides, Leuconostoc pseudomesenteroides, Streptococcus salivarius, Streptococcus millieri, Streptococcus macedonicus and Pediococcus pentosaceus. A wide phenotypic and genomic heterogeneity was observed within the different species (Lactobacillus plantarum, Lactobacillus paracasei and Leuconostoc mesenteroides) according to the origin and the time of ripening. The natural microflora was different from strain collection and each method must be combined to identify and characterize natural microflora. This study revealed the low selectivity of selective media used for the isolation of different groups of lactic acid bacteria except the Facultatively Heterofermentative lactobacilli medium selecting mesophile lactobacilli and SB medium selective for Enterococcus. The study reveals, for the first time, the microbial lactic acid bacteria community of Salers cheese and its diversity. A better knowledge of microbial flora will be useful to improve understanding of sensory quality of cheeses.
Descriptors
Cheese/microbiology, Colony Count, Microbial, DNA Fingerprinting, DNA, Bacterial/analysis, Enterococcus/genetics/isolation & purification, Fermentation, Lactobacillus/genetics/isolation & purification, Lactococcus/genetics/isolation & purification, Leuconostoc/genetics/isolation & purification, Polymerase Chain Reaction, Sequence Analysis, DNA, Streptococcus/genetics/isolation & purification
Links
Book Title
Database
Publisher
Data Source
Authors
Callon,C., Millet,L., Montel,M. C.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Knowledge, attitudes, and practices of argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in Lebanon 2004 Chaaya, M., Dept. of Epidemiol. and Pop. Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
/
Volume
29
Issue
9
Start Page
1821
Other Pages
1831
Notes
Place of Publication
ISSN/ISBN
0306-4603
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Background: Currently, little is known about argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in the Arab world, despite emerging evidence on the adverse health effects of argileh smoking and well-established knowledge about the health risks of cigarette smoking during pregnancy. Objectives: The present study assesses pregnant Arab women's knowledge of chemical contents and related harmful effects of argileh and cigarettes, their attitudes towards smoking argileh and cigarettes, and their actual smoking of argileh and cigarettes, both before and during pregnancy. Methods: A stratified sample of 864 women from 23 health care centers in Lebanon completed a structured, interviewer-administered questionnaire. Information was collected on basic demographic variables, women's knowledge, attitudes, and cigarette and argileh smoking. Results: Women were partially knowledgeable about the health risks of cigarette smoking, knew little about the harmful ingredients of argileh smoking, and had many misconceptions regarding how argileh worked or how it can produce harm. Attitudes were permissive towards all forms of smoking. Almost one quarter (23%) of participants reported smoking during pregnancy, with 17% smoking only cigarettes, 4% smoking only argileh, and 1.5% smoking both cigarette and argileh. Conclusion: A significant and growing percentage of pregnant Arab women are smoking in Lebanon, with four cigarette smokers for every argileh smoker. Smoking behaviors are empirically linked with important gaps in knowledge and with permissive attitudes. These data may be used to design more effective prevention programs targeting this vulnerable population. © 2004 Elsevier Ltd. All rights reserved.
Descriptors
adult, article, attitude, behavior, smoking, controlled study, demography, female, human, Lebanon, pregnancy
Links
Book Title
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
Chaaya,M., Jabbour,S., El-Roueiheb,Z., Chemaitelly,H.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Argileh smoking among university students: a new tobacco epidemic 2004
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine Tob Res
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Volume
6
Issue
3
Start Page
457
Other Pages
63
Notes
ID: 15203779
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
The recent global increase in argileh use represents the modern renaissance of an old public health threat and a new tobacco epidemic. This study examined argileh smoking knowledge and attitudes in a sample of university students in Beirut as determinants of argileh smoking. Data were collected cross-sectionally through self-administered questionnaires from 416 students at the American University of Beirut through stratified cluster sampling. The proportion of ever-smokers in this study was 43%, compared with the 30% reported 4 years ago. A total of 28.3% of the surveyed students were current argileh smokers, and the average initiation age was 16 years. Compared with argileh smokers, significantly greater proportions of nonsmokers had positive attitudes about argileh banning and more accurate knowledge about argileh. Argileh smoking among Lebanese young is on the rise. Students demonstrated partial knowledge and moderate to favorable attitudes concerning argileh smoking. Possible public health interventions are discussed in light of the social and cultural context of argileh use to neutralize this emerging global public health threat.
Descriptors
Adolescent Behavior, Health Knowledge, Attitudes, Practice, Smoking/ethnology, Smoking/psychology, Adolescent, Adult, Age Factors, Cross-Sectional Studies, Cultural Characteristics, Female, Health Surveys, Humans, Lebanon/ethnology, Male, Universities, Water
Links
http://pesquisa.bvsalud.org/ghl/resource/en/mdl-15203779
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Chaaya,Monique, El-Roueiheb,Zana, Chemaitelly,Hiam, Azar,Grace, Nasr,Joumana, Al-Sahab,Ban
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Perceptions of cannabis effects: A qualitative study among adolescents 2004 Chabrol, H., Ctr. d'Etud./de Rech./Psychopathol., Universite de Toulouse-Le Mirail, 31058 Toulouse, France
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Encephale
Periodical, Abbrev.
Encephale
Pub Date Free Form
/
Volume
30
Issue
3
Start Page
259
Other Pages
265
Notes
Place of Publication
ISSN/ISBN
0013-7006
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
The aim of the study was to compare perceptions of cannabis use effects and risks of tolerance effect, withdrawal syndrome, dependence and repercussions on school, social, and familial functioning among adolescent cannabis users and non users. Subjects were 210 adolescents (121 boys, 89 girls; mean age= 16.3 ± 1.3) from the department of Pyrénées-Orientales, France. Subjects completed a questionnaire assessing the frequency of cannabis use, the method of using cannabis, and including open-ended questions (What are the different methods of cannabis use? What are their pleasant and unpleasant or negative effects? What are their risks? Do you think that cannabis effects decrease in intensity when you are used to it? When someone is used to cannabis and stop using it (or has no more of it), does she experience craving for cannabis and withdrawal symptoms? What do you think of cannabis use?). Among the subjects, 118 (56.2%) were cannabis users and 92 (43.8%) were non-users. Among users, 27% used cannabis once a month or less than once a month, 21%, more than once a month; 24%, more than once a weeks; 6%, every day; 20%, more than once a day. The methods of using cannabis were joints (76%), bong (40%), pipe (23%), and ingestion (18%). Knowledge of methods of using cannabis was higher in users than non-users: joint (87% vs 64%, p < 0.0001), bong (69% vs 21%, p < 0.0001), pipe (38% vs 7%, p < 0.0001), ingestion (41% vs 13%, p < 0.0001). Fifty-four per cent of users reported that cannabis use induces pleasant affects versus 30% of non-users (p = 0.0006). They were exhilaration (47% vs 9%), relaxation (40% vs 23%), cheerfulness (21% vs 10%). Twenty-seven percent of users reported that cannabis use reduces negative feelings versus 14% of non-users (p = 0.02). To be more open to social relationships was mentioned by 13% of users versus 1% of non-users (p = 0.0001). The negative effects that were reported were attention and cognitive impairment (13% of users vs 5% of non users, p = 0.05), irritability (8% vs 8%), loss of control (8% vs 8%) and feeling faint (13% vs 6%, p = 0.09). Users reported than bong has much quicker and stronger effects than joints. The effects of bong class cannabis as a hard drug. Physical negative effects or risk were reported by 35% of users versus 30% of non-users (p = 0.44). Bong users described specific physical risks such as respiratory problems and fainting. No subjects reported the risk of road accidents. Most users and non-users considered that cannabis use causes dependence (60% vs 74%, p = 0.03), tolerance (68% vs 60%, p = 0.23), and withdrawal symptoms (76% vs 52%, p < 0.001). A minority of users and non-users reported that cannabis use causes a deterioration in school functioning (42% vs 20%, p = 0.69), in social activities (23% vs 14%, p = 0.10) and in family relationships (29% vs 20%, p = 0.14). Most of users (56%) had a global positive opinion of cannabis use whereas most non-users (66%) had a global negative opinion of cannabis use. The frequency and methods of use reported in this study compare with the results of a recent study carried out in another town of the south of France. These results suggest that a high proportion of French adolescents are using cannabis and that a high proportion of users utilize bongs. Perception of cannabis effects and risks of tolerance effect, withdrawal syndrome, dependence and repercussions on school, social, and familial functioning differed between users and non-users. Users have more positive beliefs and less negative beliefs about cannabis than non-users. Users reported more frequently pleasant effects and less frequently unpleasant or negative effects, physical risks, risks of dependence, deterioration in school, social, and familial functioning than non-users. However, only a minority of non-users reported negative effects or consequences of cannabis use. None subjects reported a risk of road accident. These results suggest that information on
Descriptors
cannabis, academic achievement, adolescent, article, attention deficit disorder, cannabis addiction, cognitive defect, drug effect, drug tolerability, drug use, faintness, family, female, France, human, human relation, irritability, leisure, male, normal human, perception, psychoanalysis, qualitative analysis, questionnaire, risk assessment, social aspect, social behavior, withdrawal syndrome
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Book Title
Les représentations des effets du cannabis: Une étude qualitative chez les adolescents consommateurs et non consommateurs
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
Chabrol,H., Roura,C., Kallmeyer,A.
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Date of Electronic
PMCID
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