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Crystal structures of trans-di-chlorido-tetra-kis-[1-(2,6-diiso-propyl-phen-yl)-1H-imidazole-kappaN (3)]iron(II), trans-di-bromido-tetra-kis-[1-(2,6-diiso-propyl-phen-yl)-1H-imidazole-kappaN (3)]iron(II) and trans-di-bromido-tetra-kis-[1-(2,6-diiso-propyl 2014 Department of Chemistry, University of Fribourg, Av. de Perolles, CH-1700 Fribourg, Switzerland.; Department of Chemistry, University of Fribourg, Av. de Perolles, CH-1700 Fribourg, Switzerland.; Benefri Crystallography Service, University of Neuchatel, A
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Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
19-Jul
Volume
70
Issue
Pt 8
Start Page
72
Other Pages
76
Notes
LR: 20140926; JID: 101089178; OID: NLM: PMC4158527; OTO: NOTNLM; 2014/08/01 [ecollection]; 2014/06/12 [received]; 2014/06/15 [accepted]; 2014/07/19 [epublish]; epublish
Place of Publication
United States
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 25249858
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536814014056 [doi]
Output Language
Unknown(0)
PMID
25249858
Abstract
The title compounds, [FeCl2(C15H20N2)4], (I), [FeBr2(C15H20N2)4], (II), and [FeBr2(C15H20N2)4].2C4H10O, (IIb), respectively, all have triclinic symmetry, with (I) and (II) being isotypic. The Fe(II) atoms in each of the structures are located on an inversion center. They have octa-hedral FeX 2N4 (X = Cl and Br, respectively) coordination spheres with the Fe(II) atom coordinated by two halide ions in a trans arrangement and by the tertiary N atom of four aryl-imidazole ligands [1-(2,6-diiso-propyl-phen-yl)-1H-imidazole] in the equatorial plane. In the two independent ligands, the benzene and imidazole rings are almost normal to one another, with dihedral angles of 88.19 (15) and 79.26 (14) degrees in (I), 87.0 (3) and 79.2 (3) degrees in (II), and 84.71 (11) and 80.58 (13) degrees in (IIb). The imidazole rings of the two independent ligand mol-ecules are inclined to one another by 70.04 (15), 69.3 (3) and 61.55 (12) degrees in (I), (II) and (IIb), respectively, while the benzene rings are inclined to one another by 82.83 (13), 83.0 (2) and 88.16 (12) degrees , respectively. The various dihedral angles involving (IIb) differ slightly from those in (I) and (II), probably due to the close proximity of the diethyl ether solvent mol-ecule. There are a number of C-Hcdots, three dots, centeredhalide hydrogen bonds in each mol-ecule involving the CH groups of the imidazole units. In the structures of compounds (I) and (II), mol-ecules are linked via pairs of C-Hcdots, three dots, centeredhalogen hydrogen bonds, forming chains along the a axis that enclose R 2 (2)(12) ring motifs. The chains are linked by C-Hcdots, three dots, centeredpi inter-actions, forming sheets parallel to (001). In the structure of compound (IIb), mol-ecules are linked via pairs of C-Hcdots, three dots, centeredhalogen hydrogen bonds, forming chains along the b axis, and the diethyl ether solvent mol-ecules are attached to the chains via C-Hcdots, three dots, centeredO hydrogen bonds. The chains are linked by C-Hcdots, three dots, centeredpi inter-actions, forming sheets parallel to (001). In (I) and (II), the methyl groups of an isopropyl group are disordered over two positions [occupancy ratio = 0.727 (13):0.273 (13) and 0.5:0.5, respectively]. In (IIb), one of the ethyl groups of the diethyl ether solvent mol-ecule is disordered over two positions (occupancy ratio = 0.5:0.5).
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Database
Publisher
Data Source
Authors
Mafua,R., Jenny,T., Labat,G., Neels,A., Stoeckli-Evans,H.
Original/Translated Title
URL
Date of Electronic
20140719
PMCID
PMC4158527
Editors
Clinical inquiries regarding Ebola virus disease received by CDC--United States, July 9-November 15, 2014 2014
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
12-Dec
Volume
63
Issue
49
Start Page
1175
Other Pages
1179
Notes
LR: 20150211; JID: 7802429; ppublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 25503923
Language
eng
SubFile
Journal Article; IM
DOI
mm6349a8 [pii]
Output Language
Unknown(0)
PMID
25503923
Abstract
Since early 2014, there have been more than 6,000 reported deaths from Ebola virus disease (Ebola), mostly in Guinea, Liberia, and Sierra Leone. On July 9, 2014, CDC activated its Emergency Operations Center for the Ebola outbreak response and formalized the consultation service it had been providing to assist state and local public health officials and health care providers evaluate persons in the United States thought to be at risk for Ebola. During July 9-November 15, CDC responded to clinical inquiries from public health officials and health care providers from 49 states and the District of Columbia regarding 650 persons thought to be at risk. Among these, 118 (18%) had initial signs or symptoms consistent with Ebola and epidemiologic risk factors placing them at risk for infection, thereby meeting the definition of persons under investigation (PUIs). Testing was not always performed for PUIs because alternative diagnoses were made or symptoms resolved. In total, 61 (9%) persons were tested for Ebola virus, and four, all of whom met PUI criteria, had laboratory-confirmed Ebola. Overall, 490 (75%) inquiries concerned persons who had neither traveled to an Ebola-affected country nor had contact with an Ebola patient. Appropriate medical evaluation and treatment for other conditions were noted in some instances to have been delayed while a person was undergoing evaluation for Ebola. Evaluating and managing persons who might have Ebola is one component of the overall approach to domestic surveillance, the goal of which is to rapidly identify and isolate Ebola patients so that they receive appropriate medical care and secondary transmission is prevented. Health care providers should remain vigilant and consult their local and state health departments and CDC when assessing ill travelers from Ebola-affected countries. Most of these persons do not have Ebola; prompt diagnostic assessments, laboratory testing, and provision of appropriate care for other conditions are essential for appropriate patient care and reflect hospital preparedness.
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Authors
Karwowski,M.P., Meites,E., Fullerton,K.E., Stroher,U., Lowe,L., Rayfield,M., Blau,D.M., Knust,B., Gindler,J., Van Beneden,C., Bialek,S.R., Mead,P., Oster,A.M., Centers for Disease Control and Prevention (CDC)
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Elevated temperature differently affects foliar nitrogen partitioning in seedlings of diverse Douglas fir provenances 2014 Albert-Ludwigs-Universitat Freiburg, Institut fur Forstwissenschaften, Georges-Kohler-Allee Geb. 053/054, Freiburg i. Br. D-79110, Germany Sichuan Province Key Laboratory of Ecological Security and Protection, Mianyang Normal University, Xianren Road 30,
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Print(0)
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Journal Article
Periodical, Full
Tree physiology
Periodical, Abbrev.
Tree Physiol.
Pub Date Free Form
Oct
Volume
34
Issue
10
Start Page
1090
Other Pages
1101
Notes
LR: 20151119; CI: (c) The Author 2014; JID: 100955338; 0 (Amino Acids); 1406-65-1 (Chlorophyll); N762921K75 (Nitrogen); OTO: NOTNLM; 2014/09/20 [aheadofprint]; ppublish
Place of Publication
Canada
ISSN/ISBN
1758-4469; 0829-318X
Accession Number
PMID: 25240727
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/treephys/tpu074 [doi]
Output Language
Unknown(0)
PMID
25240727
Abstract
Global climate change causes an increase in ambient air temperature, a major environmental factor influencing plant physiology and growth that already has been perceived at the regional scale and is expected to become even more severe in the future. In the present study, we investigated the effect of elevated ambient air temperature on the nitrogen metabolism of two interior provenances of Douglas fi r (Pseudotsuga menziesii var. glauca) originating from contrasting habitats, namely the provenances Monte Creek (MC) from a drier environment and Pend Oreille (PO) from a more humid environment. Three- to four-year-old seedlings of the two provenances were grown for 3 months in controlled environments under either control temperature (day 20 degrees C, night 15 degrees C) or high temperature (HT, 30/25 degrees C) conditions. Total nitrogen (N), soluble protein, chlorophyll and total amino acid (TAA) contents as well as individual amino acid concentrations were determined in both current-year and previous-year needles. Our results show that the foliar total N contents of the two provenances were unaffected by HT. Arginine, lysine, proline, glutamate and glutamine were the most abundant amino acids, which together contributed approximately 88% to the TAA pool of current- and previous-year needles. High temperature decreased the contents of most amino acids of the glutamate family (i.e., arginine, proline, ornithine and glutamine) in current-year needles. However, HT did not affect the concentrations of metabolites related to the photorespiratory pathway, such as [Formula: see text], glycine and serine. In general, current-year needles were considerably more sensitive to HT than previous-year needles. Moreover, provenance PO originating from a mesic environment showed stronger responses to HT than provenance MC. Our results indicate provenance-specific plasticity in the response of Douglas fir to growth temperature. Provenance-specific effects of elevated temperature on N-use efficiency suggest that origin might determine the sensitivity and growth potential of Douglas fir trees in a future warmer climate.
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Book Title
Database
Publisher
. Published by Oxford University Press
Data Source
Authors
Du,B., Jansen,K., Junker,L.V., Eiblmeier,M., Kreuzwieser,J., Gessler,A., Ensminger,I., Rennenberg,H.
Original/Translated Title
URL
Date of Electronic
20140920
PMCID
Editors
The assessment and management of inner ear barotrauma in divers and recommendations for returning to diving 2014 Faculty of Heath Sciences, University of Tasmania, and Medical Co-directors, Department of Diving and Hyperbaric Medicine, Royal Hobart Hospital, PO Box 744, North Hobart, Tasmania 7002, Australia, Phone: +61-(0)414-344744, Fax: +61-(0)3-6222-7268, E-mail
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Journal Article
Periodical, Full
Diving and hyperbaric medicine
Periodical, Abbrev.
Diving.Hyperb.Med.
Pub Date Free Form
Dec
Volume
44
Issue
4
Start Page
208
Other Pages
222
Notes
JID: 101282742; OTO: NOTNLM; 2014/07/06 [received]; 2014/10/15 [accepted]; ppublish
Place of Publication
Australia
ISSN/ISBN
1833-3516; 1833-3516
Accession Number
PMID: 25596834
Language
eng
SubFile
Journal Article; Review; IM
DOI
Output Language
Unknown(0)
PMID
25596834
Abstract
Inner ear barotrauma (IEBt) constitutes a spectrum of pressure-related pathology in the inner ear, with antecedent middle ear barotrauma (MEBt) common. IEBt includes perilymph fistula, intralabyrinthine membrane tear, inner ear haemorrhage and other rarer pathologies. Following a literature search, the pathophysiology, diagnosis, and treatment of IEBt in divers and best-practice recommendations for returning to diving were reviewed. Sixty-nine papers/texts were identified and 54 accessed. Twenty-five case series (majority surgical) provided guidance on diagnostic pathways; nine solely reported divers. IEBt in divers may be difficult to distinguish from inner ear decompression sickness (IEDCS), and requires dive-risk stratification and careful interrogation regarding diving-related ear events, clinical assessment, pure tone audiometry, a fistula test and electronystagmography (ENG). Once diagnosed, conservative management is the recommended first line therapy for IEBt. Recompression does not appear to cause harm if the diagnosis (IEBt vs IEDCS) is doubtful (limited case data). Exploratory surgery is indicated for severe or persisting vestibular symptoms or hearing loss, deterioration of symptoms, or lack of improvement over 10 days indicating significant pathology. Steroids are used, but without high-level evidence. It may be possible for divers to return to subaquatic activity after stakeholder risk acceptance and informed consent, provided: (1) sensorineural hearing loss is stable and not severe; (2) there is no vestibular involvement (via ENG); (3) high-resolution computed tomography has excluded anatomical predilection to IEBt and (4) education on equalising techniques is provided. There is a need for a prospective data registry and controlled trials to better evaluate diagnostic and treatment algorithms.
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Database
Publisher
Data Source
Authors
Elliott,E.J., Smart,D.R.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Predictors and patterns of cigarette and smokeless tobacco use among adolescents in 32 countries, 2007-2011 2014 Department of Social and Behavioral Sciences, Center for Global Tobacco Control, Harvard School of Public Health, Boston, Massachusetts. Electronic address: iagaku@post.harvard.edu.; Department of Social and Behavioral Sciences, Center for Global Tobacco
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Journal Article
Periodical, Full
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Periodical, Abbrev.
J.Adolesc.Health
Pub Date Free Form
Jan
Volume
54
Issue
1
Start Page
47
Other Pages
53
Notes
LR: 20150422; CI: Copyright (c) 2014; GR: 2R01 CA087477-09A2/CA/NCI NIH HHS/United States; GR: 3R01 CA125224-03/CA/NCI NIH HHS/United States; GR: R01 CA087477/CA/NCI NIH HHS/United States; GR: R01 CA125224/CA/NCI NIH HHS/United States; JID: 9102136; NIHMS
Place of Publication
United States
ISSN/ISBN
1879-1972; 1054-139X
Accession Number
PMID: 24060573
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.jadohealth.2013.07.037 [doi]
Output Language
Unknown(0)
PMID
24060573
Abstract
PURPOSE: This study compared data from 32 countries to assess predictors and patterns of cigarette and smokeless tobacco (SLT) use among students aged 13-15 years old. METHODS: Data from the 2007-2008 Global Youth Tobacco Surveys were analyzed for students aged 13-15 years in 31 countries located in all six World Health Organization regions. In addition, the 2011 National Youth Tobacco Survey was analyzed for U.S. students aged 13-15 years. Country-specific prevalence of current smoking, current SLT use, and concurrent use patterns were assessed. RESULTS: The national prevalence of current cigarette smoking among students aged 13-15 years ranged from 1.8% (Rwanda) to 32.9% (Latvia), whereas current SLT use ranged from 1.1% (Montenegro) to 14.4% (Lesotho). In the U.S. and most European countries surveyed, current smoking prevalence was significantly higher than SLT prevalence, in contrast to patterns observed in low- and middle-income countries. Also, in most of the surveyed countries outside of Europe and the United States, SLT use among girls was as common as their use of cigarettes, and not significantly different from use by boys. When compared with U.S. adolescents, the odds of SLT use were highest among African adolescents (adjusted odds ratio = 3.98; 95% CI: 2.19-7.24) followed by those in the Southeast Asian region (adjusted odds ratio = 2.76; 95% CI: 1.38-5.53). CONCLUSIONS: Region-specific patterns of tobacco use were noticed. Furthermore, it is alarming that in several low- and middle-income countries, the prevalence of SLT use among females did not differ from that among males, suggesting the possibility of a future shared burden of disease between both males and females.
Descriptors
Links
Book Title
Database
Publisher
Society for Adolescent Health and Medicine. Published by Elsevier Inc
Data Source
Authors
Agaku,I.T., Ayo-Yusuf,O.A., Vardavas,C.I., Connolly,G.
Original/Translated Title
URL
Date of Electronic
20130920
PMCID
PMC3872244
Editors
Adherence to treatment to help quit smoking: effects of task performance and coping with withdrawal symptoms 2014 Departamento de Personalidad, Evaluacion y Tratamiento Psicologico, Centro de Investigacion Cuerpo Cerebro Comportamiento (CIMCYC), Universidad de Granada, Campus Universitario de Cartuja s/n, 18071 Granada, Espana. fcalopez@ugr.es.
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Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
25-Nov
Volume
14
Issue
Start Page
1217
Other Pages
2458-14-1217
Notes
LR: 20151028; JID: 100968562; OID: NLM: PMC4289175; 2014/02/23 [received]; 2014/11/10 [accepted]; 2014/11/25 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 25424314
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2458-14-1217 [doi]
Output Language
Unknown(0)
PMID
25424314
Abstract
BACKGROUND: Currently the combined cognitive-behavioral and pharmacological treatment is the best option to quit smoking, although success rates remain moderate. This study aimed to identify predictors of continuous abstinence in an assisted smoking cessation program using combined treatment. In particular, we analyzed the effects of socio-demographic, smoking-, and treatment-related variables. In addition, we analyzed the effect of several risk factors on abstinence, and estimated a model of risk for smoking relapse. METHODS: Participants were 125 workers at the University of Granada (50 males), with an average age of 46.91 years (SD = 8.15). They were recruited between 2009 and 2013 at an occupational health clinic providing smoking cessation treatment. Baseline measures included socio-demographic data, preferred brand of cigarettes, number of years smoking, use of alcohol and/or tranquilizers, past attempts to quit, Fargerstrom Test for Nicotine Dependence, Smoking Processes of Change Scale, and Coping with Withdrawal Symptoms Interview. Participants were invited to a face-to-face assessment of smoking abstinence using self-report and cooximetry hemoglobin measures at 3, 6, and 12 months follow-up. The main outcome was smoking status coded as "relapse" versus "abstinence" at each follow-up. Kaplan-Meier survival analysis was performed to estimate the probability of continued abstinence during 12 months and log-rank tests were used to analyze differences in continued abstinence as a function of socio-demographic, smoking-, and treatment-related variables. Cox regression was used to analyze the simultaneous effect of several risk factors on abstinence. RESULTS: Using alcohol and/or tranquilizers was related to shorter abstinence. Physical exercise, the number of treatment sessions, performance of treatment tasks, and coping with withdrawal symptoms were related to prolonged abstinence. In particular, failure to perform the treatment tasks tripled the risk of relapse, while lack of coping doubled it. CONCLUSIONS: Our results show that physical exercise, performance of treatment-related tasks, and effective coping with withdrawal symptoms can prolong abstinence from smoking. Programs designed to help quit smoking can benefit from the inclusion of these factors.
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Database
Publisher
Data Source
Authors
Lopez-Torrecillas,F., Rueda,M.M., Lopez-Quirantes,E.M., Santiago,J.M., Tapioles,R.R.
Original/Translated Title
URL
Date of Electronic
20141125
PMCID
PMC4289175
Editors
Proactive tobacco treatment for low income smokers: study protocol of a randomized controlled trial 2014 VA HSR&D Center for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, 1 Veterans Drive (152), Minneapolis, MN 55417, USA. Steven.Fu@va.gov.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
9-Apr
Volume
14
Issue
Start Page
337
Other Pages
2458-14-337
Notes
LR: 20150806; ClinicalTrials.gov/NCT01123967; GR: 1R01CA141527-01/CA/NCI NIH HHS/United States; GR: R01 CA141527/CA/NCI NIH HHS/United States; JID: 100968562; OID: NLM: PMC3995758; 2014/03/27 [received]; 2014/04/02 [accepted]; 2014/04/09 [aheadofprint]; e
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 24716466
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM
DOI
10.1186/1471-2458-14-337 [doi]
Output Language
Unknown(0)
PMID
24716466
Abstract
BACKGROUND: There is a high prevalence of smoking and high burden of tobacco-related diseases among low-income populations. Effective, evidenced-based smoking cessation treatments are available, but low-income smokers are less likely than higher-income smokers to use these treatments, especially the most comprehensive forms that include a combination of pharmacotherapy and intensive behavioral counseling. METHODS/DESIGN: The primary objectives of this randomized controlled trial are to compare the effects of a proactive tobacco treatment intervention compared to usual care on population-level smoking abstinence rates and tobacco treatment utilization rates among a diverse population of low-income smokers, and to determine the cost-effectiveness of proactive tobacco treatment intervention. The proactive care intervention systematically offers low-income smokers free and easy access to evidence-based treatments and has two primary components: (1) proactive outreach to current smokers in the form of mailed invitation materials and telephone calls containing targeted health messages, and (2) facilitated access to free, comprehensive, evidence-based tobacco cessation treatments in the form of NRT and intensive, telephone-based behavioral counseling. The study aims to include a population-based sample (N = 2500) of adult smokers enrolled in the Minnesota Health Care Programs (MHCP), a state-funded health insurance plan for low-income persons. Baseline data is obtained from MHCP administrative databases and a participant survey that is conducted prior to randomization. Outcome data is collected from a follow-up survey conducted 12 months after randomization and MHCP administrative data. The primary outcome is six-month prolonged smoking abstinence at one year and is assessed at the population level. All randomized individuals are asked to complete the follow-up survey, regardless of whether they participated in tobacco treatment. Data analysis of the primary aims will follow intent-to-treat methodology. DISCUSSION: There is a critical need to increase access to effective tobacco dependence treatments. This randomized trial evaluates the effects of proactive outreach coupled with free NRT and telephone counseling on the population impact of tobacco dependence treatment. If proven to be effective and cost-effective, national dissemination of proactive treatment approaches would reduce tobacco-related morbidity, mortality, and health care costs for low income Americans. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov: NCT01123967.
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Database
Publisher
Data Source
Authors
Fu,S.S., van Ryn,M., Burgess,D.J., Nelson,D., Clothier,B., Thomas,J.L., Nyman,J.A., Joseph,A.M.
Original/Translated Title
URL
Date of Electronic
20140409
PMCID
PMC3995758
Editors
Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms 2014 BIOPEP Peptide Group, Department of Biochemistry, Science Faculty, University of Stellenbosch, Stellenbosch, South Africa.; BIOPEP Peptide Group, Department of Biochemistry, Science Faculty, University of Stellenbosch, Stellenbosch, South Africa.; Centre
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Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
Jul
Volume
58
Issue
7
Start Page
3697
Other Pages
3707
Notes
LR: 20150113; CI: Copyright (c) 2014; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Peptides); 0 (Reactive Oxygen Species); 0 (Tyrocidine); 7XU7A7DROE (Amphotericin B); F0XDI6ZL63 (caspofungin); OID: NLM: PMC4068576; 2014/04/21 [aheadofprint]
Place of Publication
United States
ISSN/ISBN
1098-6596; 0066-4804
Accession Number
PMID: 24752256
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1128/AAC.02381-14 [doi]
Output Language
Unknown(0)
PMID
24752256
Abstract
Tyrocidines are cationic cyclodecapeptides from Bacillus aneurinolyticus that are characterized by potent antibacterial and antimalarial activities. In this study, we show that various tyrocidines have significant activity against planktonic Candida albicans in the low-micromolar range. These tyrocidines also prevented C. albicans biofilm formation in vitro. Studies with the membrane-impermeable dye propidium iodide showed that the tyrocidines disrupt the membrane integrity of mature C. albicans biofilm cells. This membrane activity correlated with the permeabilization and rapid lysis of model fungal membranes containing phosphatidylcholine and ergosterol (70:30 ratio) induced by the tyrocidines. The tyrocidines exhibited pronounced synergistic biofilm-eradicating activity in combination with two key antifungal drugs, amphotericin B and caspofungin. Using a Caenorhabditis elegans infection model, we found that tyrocidine A potentiated the activity of caspofungin. Therefore, tyrocidines are promising candidates for further research as antifungal drugs and as agents for combinatorial treatment.
Descriptors
Links
Book Title
Database
Publisher
American Society for Microbiology. All Rights Reserved
Data Source
Authors
Troskie,A.M., Rautenbach,M., Delattin,N., Vosloo,J.A., Dathe,M., Cammue,B.P., Thevissen,K.
Original/Translated Title
URL
Date of Electronic
20140421
PMCID
PMC4068576
Editors
Prevalence and characteristics of dyspepsia among college students in Zhejiang Province 2014 Meng Li, Bin Lu, Li Chu, Hong Zhou, Ming-Yan Chen, Department of Gastroenterology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China.; Meng Li, Bin Lu, Li Chu, Hong Zhou, Ming-Yan Chen, Department
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
World journal of gastroenterology
Periodical, Abbrev.
World J.Gastroenterol.
Pub Date Free Form
7-Apr
Volume
20
Issue
13
Start Page
3649
Other Pages
3654
Notes
LR: 20151119; JID: 100883448; OID: NLM: PMC3974534; OTO: NOTNLM; 2013/07/17 [received]; 2013/11/19 [revised]; 2014/01/02 [accepted]; ppublish
Place of Publication
China
ISSN/ISBN
2219-2840; 1007-9327
Accession Number
PMID: 24707150
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.3748/wjg.v20.i13.3649 [doi]
Output Language
Unknown(0)
PMID
24707150
Abstract
AIM: To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS: Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and March 2011 to participate in the self-report survey study. The questionnaire was designed to collect data regarding demographics (sex and age), general health [weight and height, to calculate body mass index (BMI)], and physical episodes related to gastrointestinal disorders. Diagnosis of dyspepsia and irritable bowel syndrome (IBS) was made according to the Rome III criteria. Gastroesophageal reflux disease (GERD) was defined by episodes of heartburn and/or acid reflux that occurred at least once a week, according to the Montreal definition. RESULTS: Of 2520 students recruited for survey participation, only 1870 (males: 967; age range: 17-32 years, mean age: 21.3 years) returned a completed questionnaire. One hundred and eight (5.67%) of the student participants fit the criteria for dyspepsia diagnosis. Stratification analysis of dyspepsia and non-dyspepsia cases showed no statistically significant differences in age or BMI; however, the prevalence of dyspepsia was significantly higher in women than in men (7.53% vs 4.14%, P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Li,M., Lu,B., Chu,L., Zhou,H., Chen,M.Y.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC3974534
Editors
Cigarette prices and smoking prevalence after a tobacco tax increase--Turkey, 2008 and 2012 2014
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
30-May
Volume
63
Issue
21
Start Page
457
Other Pages
461
Notes
JID: 7802429; ppublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 24871250
Language
eng
SubFile
Journal Article; IM
DOI
mm6321a2 [pii]
Output Language
Unknown(0)
PMID
24871250
Abstract
Raising the price of tobacco products has been shown to reduce tobacco consumption in the United States and other high-income countries, and evidence of this impact has been growing for low- and middle-income countries as well. Turkey is a middle-income country surveyed by the Global Adult Tobacco Survey (GATS) twice in a 4-year period, in 2008 and 2012. During this time, the country introduced a policy raising its Special Consumption Tax on Tobacco and implemented a comprehensive tobacco control program banning smoking in public places, banning advertising, and introducing graphic health warnings. The higher tobacco tax took effect in early 2010, allowing sufficient time for subsequent changes in prices and smoking to be observed by the time of the 2012 GATS. This report uses data from GATS Turkey to examine how cigarette prices changed after the 2010 tax increase, describe the temporally associated changes in smoking prevalence, and learn whether this smoking prevalence changed more in some demographic groups than others. From 2008 to 2012, the average price paid for cigarettes increased by 42.1%, cigarettes became less affordable, and smoking prevalence decreased by 14.6%. The largest reduction in smoking was observed among persons with lower socioeconomic status (SES), highlighting the potential role of tax policy in reducing health disparities across socioeconomic groups.
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Kostova,D., Andes,L., Erguder,T., Yurekli,A., Keskinkilic,B., Polat,S., Culha,G., Kilinc,E.A., Tasti,E., Ersahin,Y., Ozmen,M., San,R., Ozcebe,H., Bilir,N., Asma,S., Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, CDC
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