WTS database

Title	Pub Year Sort ascending	Author	SearchLink
Smoking rates and smoking cessation preferences of pregnant women attending antenatal clinics of two large Australian maternity hospitals	2014	Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; Faculty of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Australian & New Zealand Journal of Obstetrics & Gynaecology Periodical, Abbrev. Aust.N.Z.J.Obstet.Gynaecol. Pub Date Free Form Feb Volume 54 Issue 1 Start Page 53 Other Pages 58 Notes CI: (c) 2013; JID: 0001027; OTO: NOTNLM; 2013/03/27 [received]; 2013/09/23 [accepted]; 2013/11/13 [aheadofprint]; ppublish Place of Publication Australia ISSN/ISBN 1479-828X; 0004-8666 Accession Number PMID: 24471847 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1111/ajo.12148 [doi] Output Language Unknown(0) PMID 24471847 Abstract BACKGROUND: Tobacco smoking is the most important preventable cause of many adverse pregnancy outcomes. Some women continue to smoke during pregnancy although the harmful effects are evident. AIMS: To characterise pregnant smokers and to understand their smoking behaviours and preferences for smoking cessation. MATERIALS AND METHODS: Pregnant women (>/=18 years) attending the antenatal clinics of two large Victorian maternity hospitals completed a prepiloted questionnaire which included items regarding socio-demographics, smoking habits and attitudes towards quitting. RESULTS: Smoking status was self-reported by 1899 participants; 125 (6.6%) were current smokers and 604 (31.8%) were ex-smokers. There were 87 (69.6%) daily smokers and 38 (30.4%) occasional smokers. Smokers mainly had medium (54; 43.2%) or heavy nicotine dependence (45; 36%). Current smokers were younger, Australian born, not living with a partner, from a lower socio-economic background, multigravida and had a smoker in their household or among friends. Although pregnant smokers were aware of the possible complications of smoking, their motivation and confidence to quit (median) on a 10-point scale were 7 and 4, respectively. The majority of smokers preferred to stop smoking gradually (74; 71.2%). The preferred methods for quitting were medications (49; 47.6%) and hypnotherapy (35; 34.0%). Patches (28; 29.5%) were the preferred dosage form, and nicotine replacement therapy (25; 28.1%) was the preferred medication. Less than half reported that their health professionals discouraged smoking during pregnancy. CONCLUSIONS: Health professionals should be more proactive in identifying smokers and offering smoking cessation support in pregnancy. Multidisciplinary smoking cessation interventions for pregnant smokers are warranted. Descriptors Links Book Title Database Publisher The Royal Australian and New Zealand College of Obstetricians and Gynaecologists Data Source Authors Hoekzema,L., Werumeus Buning,A., Bonevski,B., Wolke,L., Wong,S., Drinkwater,P., Stewart,K., George,J. Original/Translated Title URL Date of Electronic 20131113 PMCID Editors
Unintentional injuries in childhood and adolescence: current prevalence, determinants, and trends: results of the KiGGS study: first follow-up (KiGGS Wave 1)	2014	Abteilung fur Epidemiologie und Gesundheitsmonitoring, Robert Koch-Institut, General-Pape-Strasse 62, 12101, Berlin, Deutschland, SassA@rki.de.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Periodical, Abbrev. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Pub Date Free Form Jul Volume 57 Issue 7 Start Page 789 Other Pages 797 Notes LR: 20160707; JID: 101181368; ppublish Place of Publication Germany ISSN/ISBN 1437-1588; 1436-9990 Accession Number PMID: 24950828 Language ger SubFile English Abstract; Journal Article; IM DOI 10.1007/s00103-014-1977-5 [doi] Output Language Unknown(0) PMID 24950828 Abstract BACKGROUND: In Germany and worldwide, unintentional injuries (UI) are a major health threat for children and adolescents. The first follow-up of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 1, 2009-2012) continued the national UI monitoring that started with the KiGGS baseline study (2003-2006). The present analysis provides updated information and for the first time gives indications on time trends. METHODS: KiGGS Wave 1 is a combined nationwide cross-sectional and longitudinal survey by the Robert Koch Institute (RKI) providing information about 12,368 participating children and adolescents (0-17 years old; response rates: 38.8% first time invited, 72.9% reinvited). Parents were asked about their children's UI and poisonings via telephone interviews. Information on UI is available for 11,665 children and adolescents (1-17 years old). The 12-month prevalence rate and 95% confidence interval were calculated, and KiGGS Wave 1 was compared with the KiGGS baseline study. The Rao-Scott chi-square test corrected over the F distribution was used to test for the statistical significance of subgroup differences and trend effects. RESULTS: Within the previous 12 months, 15.5% of all children and adolescents aged 1-17 years were medically treated for UI. UI were significantly more prevalent among boys (17.0%) than among girls (14.0%), and 3.4% of the subjects had more than one accident leading to UI. One in eight children and adolescents who suffered UI stayed in hospital (12.3%) for inpatient treatment for at least one night. The home, childcare and educational institutions, and sports facilities/playgrounds were the predominant accident locations. Compared to the baseline study, neither the overall prevalence of UI nor the gender- and age-specific patterns changed significantly. CONCLUSION: Since a large proportion of UI is avoidable, knowledge of high-risk subgroups and accident locations is of particular use for prevention. KiGGS Wave 1 makes an important contribution to the comprehension of these issues. The transfer of research into practice is of particular importance for the avoidance of UI. Descriptors Links Book Title Database Publisher Data Source Authors Sass,A.C., Poethko-Muller,C., Rommel,A., KiGGS Study Group Original/Translated Title Das Unfallgeschehen im Kindes- und Jugendalter - Aktuelle Pravalenzen, Determinanten und Zeitvergleich : Ergebnisse der KiGGS-Studie - Erste Folgebefragung (KiGGS Welle 1) URL Date of Electronic PMCID Editors
Patterns of current use of tobacco products among U.S. high school students for 2000-2012--findings from the National Youth Tobacco Survey	2014	Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: RArrazola@cdc.gov.; Office on Smoking and Health, National Center for Chro	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of adolescent health : official publication of the Society for Adolescent Medicine Periodical, Abbrev. J.Adolesc.Health Pub Date Free Form Jan Volume 54 Issue 1 Start Page 54 Other Pages 60000000000 Notes LR: 20160229; CI: Published by Elsevier Inc.; GR: CC999999/Intramural CDC HHS/United States; JID: 9102136; HHSPA713823; OID: NLM: HHSPA713823; OID: NLM: PMC4534716; OTO: NOTNLM; 2013/05/31 [received]; 2013/08/02 [revised]; 2013/08/02 [accepted]; 2013/09/2 Place of Publication United States ISSN/ISBN 1879-1972; 1054-139X Accession Number PMID: 24074604 Language eng SubFile Journal Article; IM DOI 10.1016/j.jadohealth.2013.08.003 [doi] Output Language Unknown(0) PMID 24074604 Abstract PURPOSE: The purpose of this study was to assess patterns and trends of tobacco use among high school students to better understand which products are used individually or concurrently. METHODS: Data from the National Youth Tobacco Survey from 2000 through 2012 were used to assess patterns and trends of current tobacco use (cigarettes, cigars, smokeless tobacco, and other tobacco products) among U.S. high school students. We assessed use of products individually and concurrently. RESULTS: During 2000-2012, overall linear declines were observed in current use of any tobacco product from 33.6% to 20.4% (p Descriptors Links Book Title Database Publisher Data Source Authors Arrazola,R.A., Kuiper,N.M., Dube,S.R. Original/Translated Title URL Date of Electronic 20130926 PMCID PMC4534716 Editors
An examination of sociodemographic correlates of ecstasy use among high school seniors in the United States	2014	New York University Langone Medical Center, Department of Population Health , New York , USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Substance use & misuse Periodical, Abbrev. Subst.Use Misuse Pub Date Free Form Nov Volume 49 Issue 13 Start Page 1774 Other Pages 1783 Notes JID: 9602153; 0 (Street Drugs); KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine); OTO: NOTNLM; 2014/06/23 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1532-2491; 1082-6084 Accession Number PMID: 24955818 Language eng SubFile Journal Article; IM DOI 10.3109/10826084.2014.926933 [doi] Output Language Unknown(0) PMID 24955818 Abstract BACKGROUND: Although ecstasy (MDMA) use is not as prevalent in the United States (US) as it was in the early 2000s, use remains popular among adolescents and young adults. Few recent studies have examined ecstasy use in national samples among those at particularly high risk for use-adolescents approaching adulthood. Research is needed to delineate sociodemographic correlates of use in this group. METHODS: Data were examined from a nationally representative sample of high school seniors in the US (modal age = 18) from the Monitoring the Future study (years 2007-2012; weighted N = 26,504). Data from all cohorts were aggregated and correlates of recent (last 12-month) use of ecstasy were examined. RESULTS: Roughly 4.4% of high school seniors reported use of ecstasy within the last year. Females and religious students were consistently at lower odds for use. Black and Hispanic students, and students residing with two parents, were at lower odds for ecstasy use, until controlling for other drug use. Odds of use were consistently increased for those residing in a city, students with weekly income of >$50 from a job, and students earning >$10 weekly from other sources. Lifetime use of alcohol, cigarettes, marijuana, and other illicit drugs each robustly increased odds of ecstasy use. CONCLUSION: Subgroups of high school seniors, defined by specific sociodemographic factors, and those who have used other drugs, are currently at high risk for ecstasy initiation and use. Since ecstasy is regaining popularity in the US, prevention efforts should consider these factors. Descriptors Links Book Title Database Publisher Data Source Authors Palamar,J.J., Kamboukos,D. Original/Translated Title URL Date of Electronic 20140623 PMCID Editors
Epidemiology of Dyspepsia and Irritable Bowel Syndrome (IBS) in Medical Students of Northern India	2014	Resident, Department of Community Medicine, Maulana Azad Medical College & Associated LN, GNEC and GB Pant Hospitals , New Delhi, India .; Under graduate student, Maulana Azad Medical College & Associated LN, GNEC and GB Pant Hospitals , New Delhi, India	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of clinical and diagnostic research : JCDR Periodical, Abbrev. J.Clin.Diagn.Res. Pub Date Free Form Dec Volume 8 Issue 12 Start Page JC13 Other Pages 6 Notes LR: 20150209; JID: 101488993; OID: NLM: PMC4316280; OTO: NOTNLM; 2014/07/29 [received]; 2014/10/16 [accepted]; 2014/12/05 [epublish]; ppublish Place of Publication India ISSN/ISBN 2249-782X; 0973-709X Accession Number PMID: 25653974 Language eng SubFile Journal Article DOI 10.7860/JCDR/2014/10710.5318 [doi] Output Language Unknown(0) PMID 25653974 Abstract BACKGROUND: Dyspepsia and Irritable Bowel Syndrome (IBS) are perhaps one of the most common gastrointestinal diseases universally. The prevalence of dyspepsia ranges from 7-40% while the prevalence of IBS ranges between 3-22% in population based studies worldwide. AIM: This study was conducted to estimate the prevalence, socio-demographic and lifestyle associated risk factors of Dyspepsia and IBS among medical college students of urban Delhi, Northern India. SETTINGS AND DESIGN: It is a cross-sectional study and was carried out from January to March 2014 at Maulana Azad Medical College, New Delhi, India. MATERIALS AND METHODS: A total of 210 students from a Medical College were asked to complete a semi-structured questionnaire based on identification and socio-demographic data, questions pertaining to lifestyle and Rome III criteria. RESULTS: Of the valid 200 subjects, 90(45%) were males and 110(55%) were females, with a mean age of 20.43+/- 1.05 y. Majority of the subjects (diagnosed with uninvestigated dyspepsia and IBS) were in the age group of 18-20 y with female gender having higher odds for both. The prevalence of dyspepsia was 18% while that of IBS was 16.5%.Consumption of fatty food, cigarettes and low physical activity were observed as most significant correlates. CONCLUSION: Rome III criteria enables symptom based diagnosis of dyspepsia and IBS.The prevalence of dyspepsia and IBS in college students from Delhi is observed to be higher. Association with lifestyle related factors highlights the importance of modifications in their prevention. Descriptors Links Book Title Database Publisher Data Source Authors Basandra,S., Bajaj,D. Original/Translated Title URL Date of Electronic 20141205 PMCID PMC4316280 Editors
Prevalence of tobacco use and exposure to environmental tobacco smoke among saudi medical students in Riyadh, Saudi Arabia	2014	Community Health Science Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia, almutairikhalidm@gmail.com.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of community health Periodical, Abbrev. J.Community Health Pub Date Free Form Aug Volume 39 Issue 4 Start Page 668 Other Pages 673 Notes JID: 7600747; 0 (Tobacco Smoke Pollution); ppublish Place of Publication Netherlands ISSN/ISBN 1573-3610; 0094-5145 Accession Number PMID: 24903238 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1007/s10900-014-9900-4 [doi] Output Language Unknown(0) PMID 24903238 Abstract This study was designed to determine the prevalence of active smoking and environmental tobacco smoke (ETS) exposure among medical students in Riyadh, Saudi Arabia, and to examine their attitudes and beliefs towards tobacco control programs. The investigation was a cross-sectional study conducted during the first semester of 2013 at King Saud University School of Medicine located in Riyadh, Saudi Arabia. Invited to participate in this study were 1,789 medical students. A descriptive data analysis was performed. A total of 805 medical students completed the questionnaire. The prevalence of experimentation with cigarette smoking was 11.3%. The estimated prevalence of current smoking among the study participants was 4.7%. The majority of the students held positive attitudes toward tobacco control and approximately 93.1% of the students felt that health care professionals should be required to receive training for cessation counseling while only 36.8% of the students reported having received any training in this area. Over the study's duration 57.7% of participants reported that ETS exposure was much higher in public places, while 13.9% reported exposure at home. This investigation revealed that ETS exposure among medical students in Riyadh is at an alarmingly high rate. The data suggests a need for a more robust smoke-free policy and a commitment to greater enforcement in public places. The results of the study also demonstrate a positive attitude among participants for tobacco control. It also indicates a need for cessation counseling and training which could be incorporated into medical school curriculum. Descriptors Links Book Title Database Publisher Data Source Authors Almutairi,K.M. Original/Translated Title URL Date of Electronic PMCID Editors
Crystal structure of 3-[({2-[bis-(2-hy-droxy-benz-yl)amino]-eth-yl}(2-hy-droxy-benz-yl)amino)-meth-yl] -2-hydroxy-5-methyl-benzaldehyde	2014	Depto. de Quimica - Universidade Federal de Santa Catarina, 88040-900 Florianopolis, Santa Catarina, Brazil.; Depto. de Quimica - Universidade Federal de Santa Catarina, 88040-900 Florianopolis, Santa Catarina, Brazil.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 21-Nov Volume 70 Issue Pt 12 Start Page 562 Other Pages 565 Notes LR: 20150113; JID: 101089178; OID: NLM: PMC4257411; OTO: NOTNLM; 2014/12/01 [ecollection]; 2014/10/29 [received]; 2014/11/06 [accepted]; 2014/11/21 [epublish]; epublish Place of Publication United States ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 25552993 Language eng SubFile Journal Article DOI 10.1107/S1600536814024465 [doi] Output Language Unknown(0) PMID 25552993 Abstract The non-symmetric title mol-ecule, C32H34N2O5, is based on a tetra-substituted ethyl-enedi-amine backbone. The mol-ecular structure consists of three hy-droxy-benzyl groups and one 2-hy-droxy-5-methyl-benzaldehyde group bonded to the N atoms of the di-amine unit. The ethyl-enedi-amine skeleton shows a regular extended conformation, while the spatial orientation of the phenol arms is governed by hydrogen bonds. In the 2-hy-droxy-5-methyl-benzaldehyde group, an intra-molecular S(6) O-Hcdots, three dots, centeredO hydrogen bond is observed between the alcohol and aldehyde functions, and the neighbouring phenol arm participates in an intra-molecular S(6) O-Hcdots, three dots, centeredN hydrogen bond. The third phenol group is involved in a bifurcated intra-molecular hydrogen bond with graph-set notation S(6) for O-Hcdots, three dots, centeredN and O-Hcdots, three dots, centeredO intra-molecular hydrogen bonds between neighbouring amine and phenol arms, respectively. Finally, the fourth phenol group acts as an acceptor in a bifurcated intra-molecular hydrogen bond and also acts as donor in an inter-molecular hydrogen bond, which connects inversion-related mol-ecules into dimers with R 4 (4)(8) ring motifs. Descriptors Links Book Title Database Publisher Data Source Authors Fonseca,A.S., Bortoluzzi,A.J. Original/Translated Title URL Date of Electronic 20141121 PMCID PMC4257411 Editors
Chronic and vaccine-preventable diseases in children and adolescents in Germany: results of the KiGGS study: first follow up (KiGGS wave 1)	2014	Abteilung fur Epidemiologie und Gesundheitsmonitoring, Robert Koch-Institut, General-Pape-Strasse 62-66, 12101, Berlin, Deutschland, neuhauserh@rki.de.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Periodical, Abbrev. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Pub Date Free Form Jul Volume 57 Issue 7 Start Page 779 Other Pages 788 Notes LR: 20160707; JID: 101181368; ppublish Place of Publication Germany ISSN/ISBN 1437-1588; 1436-9990 Accession Number PMID: 24950827 Language ger SubFile English Abstract; Journal Article; IM DOI 10.1007/s00103-014-1976-6 [doi] Output Language Unknown(0) PMID 24950827 Abstract The German Health Interview and Examination Survey for Children and Adolescents (KiGGS) 2003-2006 is the first nationwide comprehensive study on the health of children and adolescents living in Germany. The KiGGS first interview follow-up is a telephone interview study that collected, among other things, data on a number of chronic and vaccine-preventable diseases in 2009-2012 and is a combined cross-sectional and longitudinal study based on a population registry sample from the 167 KiGGS study points. The analysis is based on 12,368 respondents (7913 KiGGS follow-up participants aged 7-17 years, response 72 % and 4455 newly recruited 0- to 6-year-olds, response 42 %). Based on parent reports the lifetime prevalence of both chickenpox and pertussis has decreased in the population targeted by recently changed vaccination recommendations. For measles the prevalence remained unsatisfactorily high in each investigated age group. Of the children and adolescents aged 0-17 years 16 % (95 % confidence interval CI 15.2-17.0 %) had a long-standing chronic health condition according to the parents. Of these, however, only one in five was affected in their routine daily activities. The lifetime prevalence in 7- to 17-year-olds was 1.2 % (0.9-1.6) for epilepsy (0.4 % for the past 12 months), 5.0 % (4.4-5.7) for migraine, 0.2 % (0.1-0.3) for diabetes and in 0 to 6-year-olds 2.0 % (1.5-2.6) for heart conditions and 3.1 % (2.5-3.8) for febrile seizures with a -prevalence in 0 to 2-year-olds which are most affected of 1.0 % (0.6-1.6) in the past 12 months. The vast majority of children and adolescents in Germany are in good or very good health as suggested by other results reported in this issue; however, chronic conditions are not rare and need continuous monitoring. These results confirm that implementation of the vaccination recommendations of the German Standing Committee on Vaccination (STIKO) can lead to effective prevention of infectious diseases in Germany. Descriptors Links Book Title Database Publisher Data Source Authors Neuhauser,H., Poethko-Muller,C., KiGGS Study Group Original/Translated Title Chronische Erkrankungen und impfpraventable Infektionserkrankungen bei Kindern und Jugendlichen in Deutschland : Ergebnisse der KiGGS-Studie - Erste Folgebefragung (KiGGS Welle 1) URL Date of Electronic PMCID Editors
Micafungin at physiological serum concentrations shows antifungal activity against Candida albicans and Candida parapsilosis biofilms	2014	Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain Instituto de Investigacion Sanitaria Gregorio Maranon, Madrid, Spain mariaguembe@hotmail.com jguineaortega@yahoo.es.; Department of	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Sep Volume 58 Issue 9 Start Page 5581 Other Pages 5584 Notes LR: 20150301; CI: Copyright (c) 2014; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Lipopeptides); R10H71BSWG (micafungin); OID: NLM: PMC4135876; 2014/06/23 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 24957821 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AAC.02738-14 [doi] Output Language Unknown(0) PMID 24957821 Abstract We assessed the in vitro activity of micafungin against preformed Candida biofilms by measuring the concentration of drug causing the most fungal damage and inhibition of regrowth. We studied 37 biofilm-producing Candida spp. strains from blood cultures. We showed that micafungin was active against planktonic and sessile forms of Candida albicans strains and moderately active against Candida parapsilosis sessile cells. Concentrations of micafungin above 2 mug/ml were sufficiently high to inactivate regrowth of Candida sessile cells. Descriptors Links Book Title Database Publisher American Society for Microbiology. All Rights Reserved Data Source Authors Guembe,M., Guinea,J., Marcos-Zambrano,L.J., Fernandez-Cruz,A., Pelaez,T., Munoz,P., Bouza,E. Original/Translated Title URL Date of Electronic 20140623 PMCID PMC4135876 Editors
Prevalence and characteristics of e-cigarette users in Great Britain: Findings from a general population survey of smokers	2014	Cancer Research UK Health Behaviour Research Centre, University College London, UK; UK Centre for Tobacco and Alcohol Studies. Electronic address: jamie.brown@ucl.ac.uk.; Cancer Research UK Health Behaviour Research Centre, University College London, UK;	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addictive Behaviors Periodical, Abbrev. Addict.Behav. Pub Date Free Form Jun Volume 39 Issue 6 Start Page 1120 Other Pages 1125 Notes LR: 20150708; CI: Copyright (c) 2014; GR: 14135/Cancer Research UK/United Kingdom; GR: MR/K023195/1/Medical Research Council/United Kingdom; GR: British Heart Foundation/United Kingdom; GR: Cancer Research UK/United Kingdom; GR: Medical Research Council/U Place of Publication England ISSN/ISBN 1873-6327; 0306-4603 Accession Number PMID: 24679611 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.addbeh.2014.03.009 [doi] Output Language Unknown(0) PMID 24679611 Abstract BACKGROUND: E-cigarettes may be effective smoking cessation aids and their use by smokers has been growing rapidly. It is important to observe and assess natural patterns in the use of e-cigarettes whilst experimental data accumulates. This paper reports the prevalence of e-cigarette awareness, beliefs and usage, including brand choice, and characterises the socio-demographic and smoking profile associated with current use, among the general population of smokers and recent ex-smokers. METHODS: Data were obtained from 3538 current and 579 recent ex-smokers in a cross-sectional online survey of a national sample of smokers in Great Britain in November and December 2012. Differences between current and recent ex-smokers in the prevalence of e-cigarette awareness, beliefs and usage were examined and the socio-demographic and smoking profile associated with current use of e-cigarettes was assessed in a series of simple and multiple logistic regressions. RESULTS: Ninety-three percent of current and recent ex-smokers (n=3841) were aware of e-cigarettes. Approximately a fifth (n=884) were currently using e-cigarettes, whilst just over a third (n=1507) had ever used them. Sixty-seven percent of the sample (n=2758) believed e-cigarettes to be less harmful than cigarettes; however, almost a quarter (n=994) remained unsure. Among both current and recent ex-smokers, the most popular reasons for using were health, cutting down and quitting (each >80%) and 38% used the brand 'E-lites'. Among current smokers who were aware of but had never used e-cigarettes, approximately half (n=1040) were interested in using them in the future. Among current smokers, their use was associated with higher socio-economic status (OR=1.48, 95%CI=1.25-1.75), smoking more cigarettes (OR=1.02, 95%CI=1.01-1.03) and having a past-year quit attempt (OR=2.82, 95%CI=2.38-3.34). CONCLUSIONS: There is a near universal awareness of e-cigarettes and their use appears to be common among smokers in Great Britain although a quarter of all smokers are unsure as to whether e-cigarettes are less harmful than cigarettes. E-lites - a brand that delivers a low dose of nicotine - is the most popular. E-cigarette users appear to have higher socio-economic status, to smoke more cigarettes per day and to have attempted to quit in the past year. Descriptors Links Book Title Database Publisher The Authors. Published by Elsevier Ltd. Data Source Authors Brown,J., West,R., Beard,E., Michie,S., Shahab,L., McNeill,A. Original/Translated Title URL Date of Electronic 20140312 PMCID PMC4003532 Editors

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