WTS database

Title	Pub Year Sort ascending	Author	SearchLink
Postpartum contraception utilization among low-income women seeking immunization for infants in Mumbai, India	2014	Department of Reproductive Medicine, University of California, San Diego School of Medicine, San Diego, CA 92103, USA; Center on Gender Equity and Health, Division of Global Public Health, University of California, San Diego School of Medicine, San Diego,	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Contraception Periodical, Abbrev. Contraception Pub Date Free Form Jun Volume 89 Issue 6 Start Page 516 Other Pages 520 Notes LR: 20150601; CI: Copyright (c) 2014; GR: 1 R03 HD055120-01/HD/NICHD NIH HHS/United States; GR: K12 HD001259/HD/NICHD NIH HHS/United States; GR: K12 HD001259/HD/NICHD NIH HHS/United States; GR: T32 DA023356/DA/NIDA NIH HHS/United States; JID: 0234361; 0 ( Place of Publication United States ISSN/ISBN 1879-0518; 0010-7824 Accession Number PMID: 24560478 Language eng SubFile Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; IM DOI 10.1016/j.contraception.2014.01.001 [doi] Output Language Unknown(0) PMID 24560478 Abstract OBJECTIVE: The objective was to examine postpartum contraception utilization among Indian women seeking immunization for their infants in three low-income communities in Mumbai, India. STUDY DESIGN: We conducted a cross-sectional questionnaire of low-income postpartum women seeking immunization for their infants at three large urban health centers in Mumbai. Contraceptive utilization data were collected as part of a larger study focused on the impact of postpartum domestic violence on maternal and infant health. Descriptive, bivariate and multivariate analyses were conducted to describe and identify predictors of postpartum contraceptive utilization. RESULTS: Postpartum women aged 17-45 years (N=1049) completed the survey; 44.5% (n=467) reported resuming sexual relations with their husbands. Among these women, the majority (65.3%; n=305) reported not currently using contraception. In multivariate analyses, women who did not discuss postpartum family planning with their husbands, had not used contraception previous to the recent birth, and had experienced physical violence or forced sex were more likely to not use postpartum contraception (adjusted odds ratios=1.47-1.77). Among the 162 women using contraception, the most common time to initiation of contraception was 5 weeks postpartum, and the most common method used was condoms 77.8% (n=126). CONCLUSION: Contraception nonuse was common among urban, low-income postpartum women in India. This study highlights the importance of developing interventions to increase use of highly effective contraceptive methods postpartum, and that spousal violence and lack of marital communication may present barriers to postpartum contraception utilization. Infant immunization may represent an opportunity for provision of contraceptives and contraceptive counseling. IMPLICATIONS: This original research study is a unique contribution to the literature because it presents data regarding the nonuse of postpartum contraception among women seeking immunizations for their infants in urban centers in a developing country. It also reveals barriers to not using postpartum contraception and provides data for future interventions. Descriptors Links Book Title Database Publisher Elsevier Inc Data Source Authors Mody,S.K., Nair,S., Dasgupta,A., Raj,A., Donta,B., Saggurti,N., Naik,D.D., Silverman,J.G. Original/Translated Title URL Date of Electronic 20140110 PMCID PMC4264596 Editors
Plant nitrogen status and co-occurrence of organic and inorganic nitrogen sources influence root uptake by Scots pine seedlings	2014	Department of Forest Ecology and Management, Swedish University of Agricultural Sciences, SE-901 83 Umea, Sweden.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tree physiology Periodical, Abbrev. Tree Physiol. Pub Date Free Form Feb Volume 34 Issue 2 Start Page 205 Other Pages 213 Notes LR: 20151119; JID: 100955338; 0 (Ammonium Compounds); 0 (Inorganic Chemicals); 0 (Nitrates); 0 (Organic Chemicals); 94ZLA3W45F (Arginine); N762921K75 (Nitrogen); OTO: NOTNLM; 2014/01/30 [aheadofprint]; ppublish Place of Publication Canada ISSN/ISBN 1758-4469; 0829-318X Accession Number PMID: 24488801 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/treephys/tpt121 [doi] Output Language Unknown(0) PMID 24488801 Abstract Insights into how the simultaneous presence of organic and inorganic nitrogen (N) forms influences root absorption will help elucidate the relative importance of these N forms for plant nutrition in the field as well as for nursery cultivation of seedlings. Uptake of the individual N forms arginine, ammonium (NH4(+)) and nitrate (NO3(-)) was studied in Scots pine (Pinus sylvestris (L.)) seedlings supplied as single N sources and additionally in mixtures of NO3(-) and NH4(+) or NO3(-) and arginine. Scots pine seedlings displayed a strong preference for NH4(+)-N and arginine-N as compared with NO3(-)-N. Thus, NO3(-) uptake was generally low and decreased in the presence of NH4(+) in the high-concentration range (500 microM N), but not in the presence of arginine. Moreover, uptake of NO3(-) and NH4(+) was lower in seedlings displaying a high internal N status as a result of high N pre-treatment, while arginine uptake was high in seedlings with a high internal N status when previously exposed to organic N. These findings may have practical implications for commercial cultivation of conifers. Descriptors Links Book Title Database Publisher Data Source Authors Gruffman,L., Jamtgard,S., Nasholm,T. Original/Translated Title URL Date of Electronic 20140130 PMCID Editors
Tweeting for and against public health policy: response to the Chicago Department of Public Health's electronic cigarette Twitter campaign	2014	Washington University in St. Louis, St. Louis, MO, United States. harrisj@wustl.edu.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of medical Internet research Periodical, Abbrev. J.Med.Internet Res. Pub Date Free Form 16-Oct Volume 16 Issue 10 Start Page e238 Other Pages Notes LR: 20151029; GR: P30 DK092950/DK/NIDDK NIH HHS/United States; JID: 100959882; OID: NLM: PMC4210950; OTO: NOTNLM; 2014/06/18 [received]; 2014/09/09 [accepted]; epublish Place of Publication Canada ISSN/ISBN 1438-8871; 1438-8871 Accession Number PMID: 25320863 Language eng SubFile Journal Article; IM DOI 10.2196/jmir.3622 [doi] Output Language Unknown(0) PMID 25320863 Abstract BACKGROUND: In January 2014, the Chicago City Council scheduled a vote on local regulation of electronic cigarettes as tobacco products. One week prior to the vote, the Chicago Department of Public Health (CDPH) released a series of messages about electronic cigarettes (e-cigarettes) through its Twitter account. Shortly after the messages, or tweets, were released, the department's Twitter account became the target of a "Twitter bomb" by Twitter users sending more than 600 tweets in one week against the proposed regulation. OBJECTIVE: The purpose of our study was to examine the messages and tweet patterns in the social media response to the CDPH e-cigarette campaign. METHODS: We collected all tweets mentioning the CDPH in the week between the e-cigarette campaign and the vote on the new local e-cigarette policy. We conducted a content analysis of the tweets, used descriptive statistics to examine characteristics of involved Twitter users, and used network visualization and descriptive statistics to identify Twitter users prominent in the conversation. RESULTS: Of the 683 tweets mentioning CDPH during the week, 609 (89.2%) were anti-policy. More than half of anti-policy tweets were about use of electronic cigarettes for cessation as a healthier alternative to combustible cigarettes (358/609, 58.8%). Just over one-third of anti-policy tweets asserted that the health department was lying or disseminating propaganda (224/609, 36.8%). Approximately 14% (96/683, 14.1%) of the tweets used an account or included elements consistent with "astroturfing"-a strategy employed to promote a false sense of consensus around an idea. Few Twitter users were from the Chicago area; Twitter users from Chicago were significantly more likely than expected to tweet in support of the policy. CONCLUSIONS: Our findings may assist public health organizations to anticipate, recognize, and respond to coordinated social media campaigns. Descriptors Links Book Title Database Publisher Data Source Authors Harris,J.K., Moreland-Russell,S., Choucair,B., Mansour,R., Staub,M., Simmons,K. Original/Translated Title URL Date of Electronic 20141016 PMCID PMC4210950 Editors
Legionella contamination in hospitals of the Campania Region: five years of environmental surveillance results	2014	Dipartimento di Scienze Mediche Preventive, Universita degli Studi di Napoli "Federico II", Italy.; Dipartimento di Scienze Mediche Preventive, Universita degli Studi di Napoli "Federico II", Italy.; Dipartimento di Scienze Mediche Preventive, Universita	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Annali di Igiene : Medicina Preventiva e di Comunita Periodical, Abbrev. Ann.Ig. Pub Date Free Form Jan-Feb Volume 26 Issue 1 Start Page 89 Other Pages 96 Notes JID: 9002865; ppublish Place of Publication Italy ISSN/ISBN 1120-9135; 1120-9135 Accession Number PMID: 24452187 Language eng SubFile Journal Article; IM DOI 10.7416/ai.2014.1961 [doi] Output Language Unknown(0) PMID 24452187 Abstract OBJECTIVE: The purpose of this study was to assess the presence and the distribution of Legionella serotypes in 50 hospital facilities in the Campania Region (Italy) through the sampling of their waters. METHODS: From January 2008 to December 2012, in compliance with the Italian Monitoring Guidelines for Legionellosis, 4.842 water samples were collected from the end points of hot water distribution networks, air conditioning systems, boilers and cooling towers. RESULTS: 1.426 (29.4%) of the 4.842 samples resulted positive for Legionella spp, with a bacterial average of 3.40 log10 cfu/L. The frequency of Legionella isolation in the specimens progressively decreased during the study (43.8% in 2008 vs 22.9% in 2012). Samples from cooling towers (32.7%), showers and taps (31.9%) revealed a more frequent presence of the microorganism, although considerable bacterial concentration variability was found in all examined points. A bacterial average of 3.33 + 0.88 log10 cfu/L was detected in cooling towers, whereas the lowest values (2.89 + 0.92 cfu/L) were found in ACSs. The most frequently isolated species were L. pneumophila 2-14, detected in 60.6% of positive samples. Within serotypes, types 6 (23.8%), 8 (21.9%) and 3 (21.4%) resulted as being the most representative. CONCLUSIONS: A significant contamination was found in examined centers. It is therefore advisable to systematically implement currently available surveillance and monitoring strategies through the scrupulous monitoring of systems as well as through the application of validated and effective procedures. Descriptors Links Book Title Database Publisher Data Source Authors Torre,I., Diana,M.V., Iervolino,C., Borriello,T., Imperato,O.C., Maccarino,S., Pennino,F. Original/Translated Title URL Date of Electronic PMCID Editors
Assessing the potential biological implications of recreational inshore fisheries on sub-tidal fish communities of Azores (north-east Atlantic Ocean) using catch and effort data	2014	University of Azores, Department of Oceanography and Fisheries, Rua Prof. Doutor Frederico Machado, 9901-862 Horta, Portugal.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of fish biology Periodical, Abbrev. J.Fish Biol. Pub Date Free Form Apr Volume 84 Issue 4 Start Page 952 Other Pages 970 Notes CI: (c) 2014; JID: 0214055; OTO: NOTNLM; 2013/05/14 [received]; 2014/01/08 [revised]; 2014/01/08 [accepted]; 2014/03/25 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1095-8649; 0022-1112 Accession Number PMID: 24665895 Language eng SubFile Journal Article; IM DOI 10.1111/jfb.12336 [doi] Output Language Unknown(0) PMID 24665895 Abstract Recreational inshore fishing activities practiced on Faial and Pico Islands (Azorean archipelago) were surveyed between October 2004 and September 2005. Recreational inshore fishers employ three main methods of fishing (shore angling, spear fishing and intertidal collecting). The method that demanded the highest fishing effort (number of fishing operations) was shore angling, followed by intertidal collecting and spear fishing. Shore angling produced the highest diversity of catch composition (38), which is in part explained by the seven fishing techniques used by shore anglers. The estimates of annual catch were higher for shore angling than spear fishing (51.2 and 6.3 t) even though they were lower than commercial artisanal fishing (442 t). The weighted mean trophic level and vulnerability index values in the fish catch were higher for spear fishing (3.4 and 50.9) than for shore angling (3.1 and 44.5). Cumulative pressure by different recreational fishing activities was detected on species already subject to a heavy pressure from Azorean commercial fishing, and on vulnerable and top-predator species. There are important biological and ecological implications whereby fishery managers should implement additional regulations such as prohibiting catches of the most vulnerable species. Descriptors Links Book Title Database Publisher The Fisheries Society of the British Isles Data Source Authors Diogo,H., Pereira,J.G. Original/Translated Title URL Date of Electronic 20140325 PMCID Editors
Use of headspace sorptive extraction coupled to gas chromatography-mass spectrometry for the analysis of volatile polycyclic aromatic hydrocarbons in herbal infusions	2014	Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30071 Murcia, Spain.; Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of Interna	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 22-Aug Volume 1356 Issue Start Page 38 Other Pages 44 Notes CI: Copyright (c) 2014; JID: 9318488; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Solvents); OTO: NOTNLM; 2014/04/29 [received]; 2014/06/17 [revised]; 2014/06/18 [accepted]; 2014/06/24 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 25001331 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2014.06.060 [doi] Output Language Unknown(0) PMID 25001331 Abstract A solvent-free method is described for the determination of 10 volatile polycyclic aromatic hydrocarbons (PAHs), considered as priority pollutants by the EU, in different herbal infusions using headspace sorptive extraction (HSSE) and gas chromatography-mass spectrometry (GC-MS). The parameters affecting both the extraction and thermal desorption steps in the HSSE were optimized by means of Plackett-Burman designs. Ten millilitres of the herbal infusion was submitted to the HSSE preconcentration in the presence of salt for 4h at 88 degrees C. The use of d(10)-phenanthrene as internal standard not only improved the repeatability of the method but allowed quantification of the samples against external aqueous standards. Detection limits ranged between 11 and 26 ng L(-1). Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Cacho,J.I., Campillo,N., Vinas,P., Hernandez-Cordoba,M. Original/Translated Title URL Date of Electronic 20140624 PMCID Editors
Application of beta-cyclodextrin-modified, carbon nanotube-reinforced hollow fiber to solid-phase microextraction of plant hormones	2014	Key Laboratory of Chemistry of Northwestern Plant Resources of the CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China; University of Chinese Academy o	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 29-Dec Volume 1374 Issue Start Page 23 Other Pages 30 Notes LR: 20151119; CI: Copyright (c) 2014; JID: 9318488; 0 (Glycolates); 0 (Nanotubes, Carbon); 0 (Naphthaleneacetic Acids); 0 (Plant Growth Regulators); 0 (beta-Cyclodextrins); 33T7G7757C (1-naphthaleneacetic acid); 717GVR334R (2-naphthoxyacetic acid); JV039J Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 25435464 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2014.11.029 [doi] Output Language Unknown(0) PMID 25435464 Abstract A new, efficient, and environmental friendly solid-phase microextraction (SPME) medium based on beta-cyclodextrin (beta-CD)-modified carbon nanotubes (CNTs) and a hollow fiber (HF) was prepared. Functionalized beta-CD was covalently linked to the surface of the carboxylic CNTs and then the obtained nanocomposite was immobilized into the wall pores of HFs under ultrasonic-assisted effect. The scanning electron microscope was used to inspect surface characteristics of fibers, demonstrating the presence of nanocomposites in their wall pores. The reinforced HF was employed in SPME, and its extraction performance was evaluated by analyzing 1-naphthaleneacetic acid (NAA) and 2-naphthoxyacetic acid (2-NOA) in vegetables. Without any tedious clean-up procedure, analytes were extracted from the sample to the adsorbent and organic solvent immobilized in HFs and then desorbed in acetonitrile prior to chromatographic analysis. Under the optimized extraction conditions, the method provided 275- and 283-fold enrichment factors of NAA and 2-NOA, low limits of detection and quantification (at an ngg(-1) level), satisfactory spiked recoveries, good inter-fiber repeatability, and batch-to-batch reproducibility. The selectivity of the developed fiber was investigated to three structurally similar compounds and two reference compounds with recognition coefficients up to 3.18. The obtained results indicate that the newly developed fiber is a feasible, selective, green, and cost-effective microextraction medium and could be successfully applied for extraction and determination of naphthalene-derived plant hormones in complex matrices. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Song,X.Y., Ha,W., Chen,J., Shi,Y.P. Original/Translated Title URL Date of Electronic 20141118 PMCID Editors
Use of e-cigarettes by individuals with mental health conditions	2014	Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA.; Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA.; Cancer Center, University of Cali	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Jul Volume 23 Suppl 3 Issue Start Page iii48 Other Pages 53 Notes LR: 20151119; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: U01 CA154280/CA/NCI NIH HHS/United States; JID: 9 Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 24824516 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1136/tobaccocontrol-2013-051511 [doi] Output Language Unknown(0) PMID 24824516 Abstract BACKGROUND: Individuals with mental health conditions (MHC) have disproportionately high tobacco-related morbidity and mortality due to high smoking prevalence rates. As high consumers of cigarettes, smokers with MHC may consider using e-cigarettes as an alternative form of nicotine delivery. OBJECTIVE: Examination of the susceptibility to use e-cigarettes by individuals with MHC. METHODS: A U.S. population survey with a national probability sample (n=10,041) was used to assess ever use and current use of regular cigarettes, e-cigarettes, and U.S. Food and Drug Administration-approved pharmacotherapy for smoking cessation. Survey respondents provided information about whether they had been diagnosed with an anxiety disorder, depression, or other MHC. RESULTS: Individuals with MHC were more likely to have tried e-cigarettes (14.8%) and to be current users of e-cigarettes (3.1%) than those without MHC (6.6% and 1.1%, respectively; p Descriptors Links Book Title Database Publisher Data Source Authors Cummins,S.E., Zhu,S.H., Tedeschi,G.J., Gamst,A.C., Myers,M.G. Original/Translated Title URL Date of Electronic 20140512 PMCID PMC4145659 Editors
CTX-M-137, a hybrid of CTX-M-14-like and CTX-M-15-like beta-lactamases identified in an Escherichia coli clinical isolate	2014	Department of Immunology, Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, China Key Laboratory of Tropical Diseases Control (Sun Yat-sen University), Ministry of Education, Guangz	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of antimicrobial chemotherapy Periodical, Abbrev. J.Antimicrob.Chemother. Pub Date Free Form Aug Volume 69 Issue 8 Start Page 2081 Other Pages 2085 Notes CI: (c) The Author 2014; GENBANK/KF790923; JID: 7513617; 0 (Anti-Bacterial Agents); 0 (DNA, Bacterial); 0 (Mutant Chimeric Proteins); 23521W1S24 (Clavulanic Acid); 9M416Z9QNR (Ceftazidime); EC 3.5.2.- (beta-lactamase CTX-M-14); EC 3.5.2.- (beta-lactamase Place of Publication England ISSN/ISBN 1460-2091; 0305-7453 Accession Number PMID: 24777903 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/jac/dku126 [doi] Output Language Unknown(0) PMID 24777903 Abstract OBJECTIVES: To characterize a novel CTX-M chimera, CTX-M-137, from Escherichia coli clinical isolates in China. METHODS: Isolates were collected from five hospitals between 22 February 2009 and 20 December 2011. Resistance genes were investigated by PCR. blaCTX-M-137 was cloned and purified for kinetic measurements. Conjugation experiments, S1-PFGE and Southern blotting were performed to study the plasmid harbouring blaCTX-M-137. The genetic environment of blaCTX-M-137 was determined by genomic cloning and sequencing. RESULTS: A total of 247 cephalosporin-resistant E. coli were identified. blaCTX-M group genes were the most prevalent extended-spectrum beta-lactamase (ESBL) genes, with 71 isolates harbouring blaCTX-M-1 group genes and 137 isolates harbouring blaCTX-M-9 group genes. A novel chimera of CTX-M-14-like and CTX-M-15-like ESBLs, designated CTX-M-137, was identified from a 60-year-old man with a urinary tract infection. The N-terminus of CTX-M-137 matched CTX-M-14 and the C-terminus matched CTX-M-15. CTX-M-137 conferred resistance to ceftazidime, cefotaxime and aztreonam. Purified CTX-M-137 showed good hydrolytic activity against ceftazidime and cefotaxime, and was inhibited by clavulanic acid. The blaCTX-M-137 was carried on an approximately 83 kb IncI1 plasmid. blaCTX-M-137 was carried on a complete transposition unit ISEcp1-blaCTX-M-137-Deltaorf477 inserted into yagA, which is part of the IncI1 plasmid backbone. CONCLUSIONS: We identified a novel CTX-M chimera, CTX-M-137, with a CTX-M-14-like N-terminus and a CTX-M-15-like C-terminus. Our findings suggest an ongoing diversification of CTX-M-type ESBLs through recombination events. Descriptors Links Book Title Database Publisher . Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy Data Source Authors Tian,G.B., Huang,Y.M., Fang,Z.L., Qing,Y., Zhang,X.F., Huang,X. Original/Translated Title URL Date of Electronic 20140428 PMCID Editors
E-cigarette versus nicotine inhaler: comparing the perceptions and experiences of inhaled nicotine devices	2014	Rutgers-Robert Wood Johnson Medical School, Division of General Internal Medicine, 125 Paterson Street, Suite 2300, New Brunswick, NJ, 08903, USA, michael.steinberg@rutgers.edu.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of general internal medicine Periodical, Abbrev. J.Gen.Intern.Med. Pub Date Free Form Nov Volume 29 Issue 11 Start Page 1444 Other Pages 1450 Notes LR: 20160701; GR: P30 CA072720/CA/NCI NIH HHS/United States; GR: P30CA072720/CA/NCI NIH HHS/United States; GR: P50 DA036107/DA/NIDA NIH HHS/United States; GR: P50-DA-036105-01/DA/NIDA NIH HHS/United States; GR: P50-DA-036107-01/DA/NIDA NIH HHS/United Stat Place of Publication United States ISSN/ISBN 1525-1497; 0884-8734 Accession Number PMID: 24830741 Language eng SubFile Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1007/s11606-014-2889-7 [doi] Output Language Unknown(0) PMID 24830741 Abstract BACKGROUND: Novel nicotine delivery products, such as electronic cigarettes (e-cigarettes), have dramatically grown in popularity despite limited data on safety and benefit. In contrast, the similar U.S. Food and Drug Administration (FDA)-approved nicotine inhaler is rarely utilized by smokers. Understanding this paradox could be helpful to determine the potential for e-cigarettes as an alternative to tobacco smoking. OBJECTIVE: To compare the e-cigarette with the nicotine inhaler in terms of perceived benefits, harms, appeal, and role in assisting with smoking cessation. DESIGN: A cross-over trial was conducted from 2012 to 2013 PARTICIPANTS/INTERVENTIONS: Forty-one current smokers age 18 and older used the e-cigarette and nicotine inhaler each for 3 days, in random order, with a washout period in between. Thirty-eight participants provided data on product use, perceptions, and experiences. MAIN MEASURES: The Modified Cigarette Evaluation Questionnaire (mCEQ) measured satisfaction, reward, and aversion. Subjects were also asked about each product's helpfulness, similarity to cigarettes, acceptability, image, and effectiveness in quitting smoking. Cigarette use was also recorded during the product-use periods. KEY RESULTS: The e-cigarette had a higher total satisfaction score (13.9 vs. 6.8 [p Descriptors Links Book Title Database Publisher Data Source Authors Steinberg,M.B., Zimmermann,M.H., Delnevo,C.D., Lewis,M.J., Shukla,P., Coups,E.J., Foulds,J. Original/Translated Title URL Date of Electronic 20140515 PMCID PMC4238186 Editors

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