Image
WTS Database
The subject of interest is:
waterpipe, water-pipe, nargile, narghile, arguileh, arguile, shisha, sheesha, chichi, hubble bubble, hubbly bubbly, goza, hookah, bong
| Title | Pub Year Sort ascending | Author | SearchLink |
|---|---|---|---|
| An observational study of group waterpipe use in a natural environment | 2014 | Department of Psychology, Center for Neuroscience, West Virginia University, Morgantown, WV; | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Jan
Volume
16
Issue
1
Start Page
93
Other Pages
99
Notes
LR: 20150423; GR: R01CA120142/CA/NCI NIH HHS/United States; JID: 9815751; 0 (Tobacco Smoke Pollution); OID: NLM: PMC3864492; 2013/08/13 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 23943842
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1093/ntr/ntt120 [doi]
Output Language
Unknown(0)
PMID
23943842
Abstract
INTRODUCTION: To date research on tobacco smoking with a waterpipe (hookah, narghile, and shisha) has focused primarily on the individual user in a laboratory setting. Yet, waterpipe tobacco smoking is often a social practice that occurs in cafes, homes, and other natural settings. This observational study examined the behavior of waterpipe tobacco smokers and the social and contextual features of waterpipe use among groups in their natural environment. METHODS: Trained observers visited urban waterpipe cafes on multiple occasions during an 8-month period. Observations of 241 individual users in naturally formed groups were made on smoking topography (puff frequency, duration, and interpuff interval [IPI]) and engagement in other activities (e.g., food and drink consumption, other tobacco use, and media viewing). RESULTS: Most users were male in group sizes of 3-4 persons, on average, and each table had 1 waterpipe, on average. The predominant social features during observational periods were conversation and nonalcoholic drinking. Greater puff number was associated with smaller group sizes and more waterpipes per group, while longer IPIs were associated with larger group sizes and fewer waterpipes per group. Additionally, greater puff frequency was observed during media viewing and in the absence of other tobacco use. CONCLUSIONS: Overall, the results suggest that waterpipe smoking behavior is affected by group size and by certain social activities. Discussion focuses on how these findings enhance our understanding of factors that may influence exposure to waterpipe tobacco smoke toxicants in naturalistic environments.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Blank,M.D., Brown,K.W., Goodman,R.J., Eissenberg,T.
Original/Translated Title
URL
Date of Electronic
20130813
PMCID
PMC3864492
Editors
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| Oral health condition and hygiene habits among adult patients with respect to their level of dental anxiety | 2014 | Read more... | |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Oral health & preventive dentistry
Periodical, Abbrev.
Oral Health.Prev.Dent.
Pub Date Free Form
Volume
12
Issue
3
Start Page
233
Other Pages
239
Notes
JID: 101167768; ppublish
Place of Publication
England
ISSN/ISBN
1602-1622; 1602-1622
Accession Number
PMID: 24624394
Language
eng
SubFile
Journal Article; D; IM
DOI
10.3290/j.ohpd.a31668 [doi]
Output Language
Unknown(0)
PMID
24624394
Abstract
PURPOSE: Dental anxiety is a common phenomenon influencing the relationship between a patient and a doctor as well as the course of treatment. The aim of the study was to assess the oral health status and hygiene habits among adult patients with respect to their level of dental anxiety. MATERIALS AND METHODS: 117 consecutive adult patients referred to the Department of Conservative Dentistry and Paedodontics of Wroclaw Medical University were included in the study. There were 58 women (49.57%) and 59 men (50.43%). The mean age of the patients was 36.57 +/- 16.76 years. The level of dental anxiety was assessed using the Modified Dental Anxiety Scale (MDAS). To evaluate dental health status and oral hygiene, the following indices were used: total number of decayed, missing and filled teeth (DMF/T) as well as surfaces (DMF/S), approximal plaque index (API), oral hygiene index (OHI), debris index (DI) and calculus index (CI). RESULTS: The study revealed that the patients with high MDAS presented a higher calculus index (CI). There was a negative correlation between a high level of dental anxiety measured by MDAS and the number of filled teeth (F/T) as well as the number of filled dental surfaces (F/S). There was no significant correlation between dental anxiety as measured with the MDAS and age, gender or level of education; however, smokers had a significantly higher anxiety level than non-smokers. CONCLUSIONS: Dental anxiety has a negative influence on oral health status; the higher the level of dental anxiety, the lower the number of filled teeth and the higher the calculus index. Poor dental and periodontal health may have many somatic as well as psychosocial consequences, both of which lower the quality of life of the patient.
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Book Title
Database
Publisher
Data Source
Authors
Kanaffa-Kilijanska,U., Kaczmarek,U., Kilijanska,B., Frydecka,D.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
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| Differences in quit attempts between non-Hispanic Black and White daily smokers: the role of smoking motives | 2014 | University of California, Los Angeles, Department of Psychology, United States.; University of California, Los Angeles, Department of Psychology, United States.; University of California, Los Angeles, Department of Psychology, United States; University of | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
Dec
Volume
39
Issue
12
Start Page
1769
Other Pages
1772
Notes
LR: 20150805; CI: Published by Elsevier Ltd.; GR: M01 RR000865/RR/NCRR NIH HHS/United States; GR: R03 DA030898/DA/NIDA NIH HHS/United States; GR: UL1RR033176/RR/NCRR NIH HHS/United States; GR: UL1TR000124/TR/NCATS NIH HHS/United States; JID: 7603486; NIHM
Place of Publication
England
ISSN/ISBN
1873-6327; 0306-4603
Accession Number
PMID: 25123344
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.addbeh.2014.07.001 [doi]
Output Language
Unknown(0)
PMID
25123344
Abstract
INTRODUCTION: The prevalence of smoking across racial/ethnic groups has declined over the years, yet racial health disparities for smoking persist. Studies indicate that non-Hispanic Black smokers attempt to quit smoking more often compared to non-Hispanic White smokers but are less successful at doing so. Research suggests that motives to quit smoking differ by race, however, less is known about the role of motives to smoke in explaining racial differences in attempts to quit smoking. METHODS: This study examined whether smoking motives accounted for the differential rates in quit attempts between non-Hispanic Black (n=155) and non-Hispanic White (n=159) smokers. Data were culled from a larger study of heavy-drinking smokers. The Wisconsin Index of Smoking Dependence Motives (WISDM) assessed motives to smoke. RESULTS: As expected, Black and White smokers reported similar smoking patterns, yet Black smokers reported higher rates of failed attempts to quit smoking than White smokers. Findings indicated that Black, compared to White, smokers endorsed lower scores in the negative reinforcement, positive reinforcement, and taste WISDM subscales and scores in these subscales mediated the relationship between race and quit attempts. CONCLUSIONS: In this study, Blacks, compared to Whites, endorsed lower motives to smoke, which are generally associated with successful quit attempts, yet they experienced more failed attempts to quit smoking. This study demonstrates racial health disparities at the level of smoking motives and suggests that Black smokers remain vulnerable to failed quit attempts despite reporting lower motives to smoke.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Bacio,G.A., Guzman,I.Y., Shapiro,J.R., Ray,L.A.
Original/Translated Title
URL
Date of Electronic
20140731
PMCID
PMC4320691
Editors
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| Comparative evaluation of genotoxicity by micronucleus assay in the buccal mucosa over comet assay in peripheral blood in oral precancer and cancer patients | 2014 | Molecular and Human Genetics Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata 700032, India and Department of Oral Pathology, Dr R. Ahmed Dental College and Hospital, Kolkata 700014, India.; Molecular and Human Geneti | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Mutagenesis
Periodical, Abbrev.
Mutagenesis
Pub Date Free Form
Sep
Volume
29
Issue
5
Start Page
325
Other Pages
334
Notes
CI: (c) The Author 2014; JID: 8707812; 2014/07/22 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1464-3804; 0267-8357
Accession Number
PMID: 25053835
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/mutage/geu023 [doi]
Output Language
Unknown(0)
PMID
25053835
Abstract
Early detection and quantification of DNA damage in oral premalignancy or malignancy may help in management of the disease and improve survival rates. The comet assay has been successfully utilised to detect DNA damage in oral premalignant or malignancy. However, due to the invasive nature of collecting blood, it may be painful for many unwilling patients. This study compares the micronucleus (MN) assay in oral buccal mucosa cells with the comet assay in peripheral blood cells in a subset of oral habit-induced precancer and cancer patients. For this, MN assay of exfoliated epithelial cells was compared with comet assay of peripheral blood leucocytes among 260 participants, including those with oral lichen planus (OLP; n = 52), leukoplakia (LPK; n = 51), oral submucous fibrosis (OSF; n = 51), oral squamous cell carcinoma (OSCC; n = 54) and normal volunteers (n = 52). Among the precancer groups, LPK patients showed significantly higher levels of DNA damage as reflected by both comet tail length (P cigarette + khaini > cigarette smokers > areca + khaini > areca. There was no significant difference in the comet length and MNi frequency between males and females who had oral chewing habits. An overall significant correlation was observed between MNi frequency and comet tail length with r = 0.844 and P
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the UK Environmental Mutagen Society
Data Source
Authors
Katarkar,A., Mukherjee,S., Khan,M.H., Ray,J.G., Chaudhuri,K.
Original/Translated Title
URL
Date of Electronic
20140722
PMCID
Editors
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| Development of solid-phase microextraction to study dissolved organic matter--polycyclic aromatic hydrocarbon interactions in aquatic environment | 2014 | Universite de Bordeaux, UMR 5805, EPOC-LPTC, 351 Cours de la Liberation, Talence Cedex F-33405, France; CNRS, UMR 5805, EPOC-LPTC, F-33405 Talence Cedex, France.; Universite de Bordeaux, UMR 5805, EPOC-LPTC, 351 Cours de la Liberation, Talence Cedex F-334 | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Analytica Chimica Acta
Periodical, Abbrev.
Anal.Chim.Acta
Pub Date Free Form
7-Jan
Volume
807
Issue
Start Page
51
Other Pages
60
Notes
CI: Copyright (c) 2013; JID: 0370534; 0 (Fluorescent Dyes); 0 (Humic Substances); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); AR09D82C7G (Deuterium); OTO: NOTNLM; 2013/07/17 [received]; 2013/10/18 [revised]; 2013/11/13 [accepted
Place of Publication
Netherlands
ISSN/ISBN
1873-4324; 0003-2670
Accession Number
PMID: 24356220
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.aca.2013.11.026 [doi]
Output Language
Unknown(0)
PMID
24356220
Abstract
Solid-phase microextraction coupled with gas chromatography and mass spectrometry (SPME-GC-MS) was developed for the study of interactions between polycyclic aromatic hydrocarbons (PAHs) and dissolved organic matter (DOM). After the determination of the best conditions of extraction, the tool was applied to spiked water to calculate the dissolved organic carbon water distribution coefficient (K(DOC)) in presence of different mixtures of PAHs and Aldrich humic acid. The use of deuterated naphthalene as internal standard for freely dissolved PAH quantification was shown to provide more accuracy than regular external calibration. For the first time, K(DOC) values of 18 PAHs were calculated using data from SPME-GC-MS and fluorescence quenching; they were in agreement with the results of previous studies. Competition between PAHs, deuterated PAHs and DOM was demonstrated, pointing out the non-linearity of PAH-DOM interactions and the stronger interactions of light molecular weight PAHs (higher K(DOC) values) in absence of high molecular weight PAHs.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
de Perre,C., Le Menach,K., Ibalot,F., Parlanti,E., Budzinski,H.
Original/Translated Title
URL
Date of Electronic
20131119
PMCID
Editors
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| A web-based sexual violence bystander intervention for male college students: randomized controlled trial | 2014 | Georgia State University, School of Public Health, Atlanta, GA, United States. lsalazar1@gsu.edu. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of medical Internet research
Periodical, Abbrev.
J.Med.Internet Res.
Pub Date Free Form
5-Sep
Volume
16
Issue
9
Start Page
e203
Other Pages
Notes
LR: 20150928; ClinicalTrials.gov/NCT01903876; GR: R49 CE000892/CE/NCIPC CDC HHS/United States; JID: 100959882; OID: NLM: PMC4180355; OTO: NOTNLM; 2014/03/25 [received]; 2014/08/16 [accepted]; 2014/07/12 [revised]; epublish
Place of Publication
Canada
ISSN/ISBN
1438-8871; 1438-8871
Accession Number
PMID: 25198417
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.2196/jmir.3426 [doi]
Output Language
Unknown(0)
PMID
25198417
Abstract
BACKGROUND: Bystander intervention approaches offer promise for reducing rates of sexual violence on college campuses. Most interventions are in-person small-group formats, which limit their reach and reduce their overall public health impact. OBJECTIVE: This study evaluated the efficacy of RealConsent, a Web-based bystander approach to sexual violence prevention, in enhancing prosocial intervening behaviors and preventing sexual violence perpetration. METHODS: A random probability sample of 743 male undergraduate students (aged 18 to 24 years) attending a large, urban university located in the southeastern United States was recruited online and randomized to either RealConsent (n=376) or a Web-based general health promotion program (n=367). Participants were surveyed online at baseline, postintervention, and 6-months postintervention. RealConsent was delivered via a password-protected Web portal that contained six 30-minute media-based and interactive modules covering knowledge of informed consent, communication skills regarding sex, the role of alcohol and male socialization in sexual violence, empathy for rape victims, and bystander education. Primary outcomes were self-reported prosocial intervening behaviors and sexual violence perpetration. Secondary outcomes were theoretical mediators (eg, knowledge, attitudes). RESULTS: At 6-month follow-up RealConsent participants intervened more often (P=.04) and engaged in less sexual violence perpetration (P=.04) compared to controls. In addition, RealConsent participants reported greater legal knowledge of sexual assault (P<.001 greater="" knowledge="" of="" effective="" consent="" less="" rape="" myths="" empathy="" for="" victims="" negative="" date="" attitudes="" hostility="" toward="" women="" intentions="" to="" intervene="" hyper-gender="" ideology="" positive="" outcome="" expectancies="" nonconsensual="" sex="" more="" intervening="" and="" comfort="" with="" other="" men="" inappropriate="" behaviors="" conclusions:="" our="" results="" support="" the="" efficacy="" realconsent.="" due="" its="" web-based="" format="" realconsent="" has="" potential="" broad-based="" dissemination="" thereby="" increasing="" overall="" public="" health="" impact="" on="" sexual="" violence.="" trial="" registration:="" clinicaltrials.gov:="" nct01903876="" http:="" by="" webcite="" at="">
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Salazar,L.F., Vivolo-Kantor,A., Hardin,J., Berkowitz,A.
Original/Translated Title
URL
Date of Electronic
20140905
PMCID
PMC4180355
Editors
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| Determining prenatal, early childhood and cumulative long-term lead exposure using micro-spatial deciduous dentine levels | 2014 | Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; Faculty of Dentistry, University of Sydney, Sydney, Australia.; Department of Preventive Medicine, Icahn School of Medicine at Mount | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
19-May
Volume
9
Issue
5
Start Page
e97805
Other Pages
Notes
LR: 20150805; GR: APP1028372/PHS HHS/United States; GR: P30 ES023515/ES/NIEHS NIH HHS/United States; GR: P42 ES016454/ES/NIEHS NIH HHS/United States; GR: P42ES00000/ES/NIEHS NIH HHS/United States; GR: P42ES05947/ES/NIEHS NIH HHS/United States; GR: R00 ES0
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 24841926
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1371/journal.pone.0097805 [doi]
Output Language
Unknown(0)
PMID
24841926
Abstract
The aim of this study was to assess the validity of micro-spatial dentine lead (Pb) levels as a biomarker for accurately estimating exposure timing over the prenatal and early childhood periods and long-term cumulative exposure to Pb. In a prospective pregnancy cohort sub-sample of 85 subjects, we compared dentine Pb levels measured using laser ablation-inductively coupled plasma mass spectrometry with Pb concentrations in maternal blood collected in the second and third trimesters, maternal bone, umbilical cord blood, and childhood serial blood samples collected from the ages of 3 months to >/=6 years. We found that Pb levels (as 208Pb:43Ca) in dentine formed at birth were significantly associated with cord blood Pb (Spearman rho = 0.69; n = 27; p
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Arora,M., Austin,C., Sarrafpour,B., Hernandez-Avila,M., Hu,H., Wright,R.O., Tellez-Rojo,M.M.
Original/Translated Title
URL
Date of Electronic
20140519
PMCID
PMC4026445
Editors
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| Comparison of tobacco-containing and tobacco-free waterpipe products: effects on human alveolar cells | 2014 | Department of Mechanical Engineering, American University of Beirut, Beirut, Lebanon; | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Apr
Volume
16
Issue
4
Start Page
496
Other Pages
499
Notes
LR: 20150422; GR: R01 DA025659/DA/NIDA NIH HHS/United States; GR: R01CA120142/CA/NCI NIH HHS/United States; GR: R01DA025659/DA/NIDA NIH HHS/United States; JID: 9815751; 0 (Smoke); OID: NLM: PMC4007115; 2013/12/03 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 24302635
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1093/ntr/ntt193 [doi]
Output Language
Unknown(0)
PMID
24302635
Abstract
INTRODUCTION: In recent years, a class of products marketed as "tobacco-free" alternatives for the "health conscious user" has become widely available for waterpipe (hookah, narghile, or shisha) smoking. Their adoption may be in part driven by regulations banning tobacco smoking in public places and by an increasing awareness of the hazards of waterpipe tobacco smoking. Although these products are presented in advertising as a "healthier" choice, very little is known about their health effects. METHODS: In this study, we compared the effects of smoke generated with tobacco-free and conventional tobacco-derived products on human alveolar cells. Smoke was generated with a smoking machine that precisely mimicked the puffing behavior of 15 experienced waterpipe smokers when they used conventional waterpipe tobacco products of their choice and flavor-matched tobacco-free products. Human alveolar epithelial cells (A549) were treated with particulate matter sampled from the smoke, and the effects on cell cycle, proliferation, and doubling time were measured during the subsequent 72hr. RESULTS: We found that smoke from both types of waterpipe products markedly reduced cell proliferation, caused cell cycle arrest at G0/G1, and increased cell doubling time. There were no significant differences across product in any measure. CONCLUSION: Tobacco-free and tobacco-based waterpipe products exert substantial and similar deleterious effects on human lung cells. This study adds to the nascent evidence base indicating that except for exposure to nicotine and its derivatives, use of tobacco-free waterpipe products does not present a reduced health risk relative to the use of conventional tobacco-based products.
Descriptors
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Database
Publisher
Data Source
Authors
Shihadeh,A., Eissenberg,T., Rammah,M., Salman,R., Jaroudi,E., El-Sabban,M.
Original/Translated Title
URL
Date of Electronic
20131203
PMCID
PMC4007115
Editors
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| Black carbon and particulate matter (PM2.5) concentrations in New York City's subway stations | 2014 | Department of Environmental Medicine, New York University , 57 Old Forge Road, Tuxedo, New York 10987, United States. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science & technology
Periodical, Abbrev.
Environ.Sci.Technol.
Pub Date Free Form
16-Dec
Volume
48
Issue
24
Start Page
14738
Other Pages
14745
Notes
LR: 20151210; GR: ES000260/ES/NIEHS NIH HHS/United States; GR: P30 CA016087/CA/NCI NIH HHS/United States; JID: 0213155; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Soot); 7440-44-0 (Carbon); OID: NLM: PMC4270389; 2014/11/26 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1520-5851; 0013-936X
Accession Number
PMID: 25409007
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1021/es504295h [doi]
Output Language
Unknown(0)
PMID
25409007
Abstract
The New York City (NYC) subway is the main mode of transport for over 5 million passengers on an average weekday. Therefore, airborne pollutants in the subway stations could have a significant impact on commuters and subway workers. This study looked at black carbon (BC) and particulate matter (PM2.5) concentrations in selected subway stations in Manhattan. BC and PM2.5 levels were measured in real time using a Micro-Aethalometer and a PDR-1500 DataRAM, respectively. Simultaneous samples were also collected on quartz filters for organic and elemental carbon (OC/EC) analysis and on Teflon filters for gravimetric and trace element analysis. In the underground subway stations, mean real time BC concentrations ranged from 5 to 23 mug/m(3), with 1 min average peaks >100 mug/m(3), while real time PM2.5 levels ranged from 35 to 200 mug/m(3). Mean EC levels ranged from 9 to 12.5 mug/m(3). At street level on the same days, the mean BC and PM2.5 concentrations were below 3 and 10 mug/m(3), respectively. This study shows that both BC soot and PM levels in NYC's subways are considerably higher than ambient urban street levels and that further monitoring and investigation of BC and PM subway exposures are warranted.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Vilcassim,M.J., Thurston,G.D., Peltier,R.E., Gordon,T.
Original/Translated Title
URL
Date of Electronic
20141126
PMCID
PMC4270389
Editors
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| Endoscopic screening for precancerous lesions of the esophagus in a high risk area in Northern Iran | 2014 | 1)Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2)Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gor | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Archives of Iranian medicine
Periodical, Abbrev.
Arch.Iran.Med.
Pub Date Free Form
Apr
Volume
17
Issue
4
Start Page
246
Other Pages
252
Notes
LR: 20151119; GR: Intramural NIH HHS/United States; JID: 100889644; 0 (Coloring Agents); 0 (Iodides); 0 (Tea); T66M6Y3KSA (Lugol's solution); ppublish
Place of Publication
Iran
ISSN/ISBN
1735-3947; 1029-2977
Accession Number
PMID: 24724600
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; IM
DOI
014174/AIM.006 [doi]
Output Language
Unknown(0)
PMID
24724600
Abstract
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a major health problem in many developing countries including Iran. ESCC has a very poor prognosis, largely due to late diagnosis. As a first step in developing an early detection and treatment program, we conducted a population-based endoscopic screening for ESCC and its precursor lesion, esophageal squamous dysplasia (ESD) in asymptomatic adults from Golestan Province, northern Iran, a high-risk area for ESCC, to evaluate the feasibility of such a program and to document the prevalence and risk factor correlates of ESD. METHODS: This cross-sectional study was conducted among participants of the Golestan Cohort Study (GCS), a population-based cohort of 50,000 adults in eastern Golestan Province. Randomly selected GCS participants were invited by telephone. Those who accepted were referred to a central endoscopy clinic. Eligible subjects were consented and then asked to fill in a brief questionnaire. Detailed information about selected risk factors was obtained from the GCS main database. Endoscopic examination with Lugol's iodine staining was performed, biopsies were taken from unstained lesions as well as the normally stained mucosa of the esophagus, and the biopsies were diagnosed by expert pathologists according to previously described criteria. RESULTS: In total, 1906 GCS subjects were invited, of whom only 302 subjects (15.8%) were successfully enrolled. Esophagitis (29.5%) and ESD (6.0%) were the most common pathological diagnoses. Turkmen ethnicity (adjusted OR = 8.61; 95%CI: 2.48-29.83), being older than the median age (OR = 7.7; 95% CI: 1.99-29.87), and using deep frying cooking methods (OR = 4.65; 95%CI: 1.19-18.22) were the strongest predictors for ESD. There were significant relationships between esophagitis and smoking (p-value
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Data Source
Authors
Roshandel,G., Khoshnia,M., Sotoudeh,M., Merat,S., Etemadi,A., Nickmanesh,A., Norouzi,A., Pourshams,A., Poustchi,H., Semnani,S., Ghasemi-Kebria,F., Noorbakhsh,R., Abnet,C., Dawsey,S.M., Malekzadeh,R.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
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