WTS database

Title	Pub Year Sort ascending	Author	SearchLink
In vitro biofilm formation and relationship with antifungal resistance of Candida spp. isolated from vaginal and intrauterine device string samples of women with vaginal complaints	2011	Kocaeli University Faculty of Medicine, Department of Medical Microbiology, Kocaeli, Turkey.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Mikrobiyoloji bulteni Periodical, Abbrev. Mikrobiyol.Bul. Pub Date Free Form Oct Volume 45 Issue 4 Start Page 697 Other Pages 706 Notes LR: 20131121; JID: 7503830; 0 (Antifungal Agents); 304NUG5GF4 (Itraconazole); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); ppublish Place of Publication Turkey ISSN/ISBN 0374-9096; 0374-9096 Accession Number PMID: 22090300 Language tur SubFile English Abstract; Journal Article; IM DOI Output Language Unknown(0) PMID 22090300 Abstract Intrauterin device (IUD) application is a widely used effective, safe and economic method for family planning. However IUD use may cause certain changes in vaginal ecosystem and may disturb microflora leading to increased colonization of various opportunistic pathogen microorganisms. The aims of this study were (i) to detect the biofilm production characteristics of Candida spp. isolated from vaginal and IUD string samples of women with IUDs, and (ii) to investigate the relationship between biofilm production and antifungal resistance. A total of 250 women (mean age: 34.4 +/- 7.6 years) admitted to gynecology outpatient clinics with vaginal symptoms (discharge and itching) were included in the study. The patients have been implanted CuT380a type IUDs for a mean duration of 59.8 +/- 42.4 months. Without removing IUD, string samples were obtained by cutting and simultaneous vaginal swab samples were also collected. Isolated Candida spp. were identified by conventional methods and API 20C AUX (BioMerieux, Fransa) system. Minimal inhibitory concentrations (MIC) of fluconazole, itraconazole and amphotericin B were determined by broth microdilution method according to the CLSI guidelines. Biofilm formation was evaluated by crystal violet staining and XTT-reduction assays, and the isolates which yielded positive results in both of the methods were accepted as biofilm-producers. In the study, Candida spp. were isolated from 33.2% (83/250) of the vaginal and 34% (85/250) of the IUD string samples, C.albicans being the most frequently detected species (54 and 66 strains for the samples, respectively). The total in vitro biofilm formation rate was 25% (21/83) for vaginal isolates and 44.7% (38/85) for IUD string isolates. Biofilm formation rate of vaginal C.albicans isolates was significantly lower than vaginal non-albicans Candida spp. (14.8% and 44.8%, respectively; p= 0.003). Biofilm formation rate of C.albicans strains isolated from vaginal and IUD string samples were found as 14.8% (8/54) and 45.5% (30/66), with a statistically significant importance (p 0.05]. Fluconazole resistance was significantly higher in biofilm-producing vaginal Candida spp. than those of nonproducers (52.4% vs. 16.1%; p= 0.001), however, itraconazole resistance was found similar in biofilmproducer and non-producer isolates (47.6% vs. 32.3%; p> 0.05). Resistance rates for both fluconazole and itraconazole were higher in biofilm-producers (39.5% and 52.6%, respectively), than those of non-producers (10.6% and 29.8%, respectively), representing a statistical significance (p= 0.002 and p= 0.03, respectively) for Candida spp. strains isolated from IUD string samples. The overall resistance rates of C.albicans and non-albicans Candida spp. against fluconazole, were determined as 15% and 54.2%, respectively, while those rates were 24.2% and 68.7%, respectively, against itraconazole. MIC value of amphotericin B for all of the Candida spp. isolates was = 1.5 microg/ml. In conclusion, the data obtained from this study revealed that Candida spp. May lead to vaginal infections by inducing biofilm formation in IUD strings and these biofilms may be related to resistance to antifungal agents. Thus, women using IUDs should be followed-up periodically for the development of biofilms in their IUD strings. Descriptors Links Book Title Database Publisher Data Source Authors Caliskan,S., Keceli Ozcan,S., Cinar,S., Corakci,A., Caliskan,E. Original/Translated Title Vajinal Yakinmasi Olan Kadinlarin Vajen ve Rahim Ici Arac Ipi Orneklerinden Izole Edilen Candida Turlerinin In Vitro Biyofilm Olusturma Ozellikleri ve Antifungal Direnc ile Iliskisi URL Date of Electronic PMCID Editors
Waterpipe (hookah) tobacco smoking among youth	2011	Department of Community and Family Health, University of South Florida, College of Public Health (MDC 056), Tampa, FL, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Current problems in pediatric and adolescent health care Periodical, Abbrev. Curr.Probl.Pediatr.Adolesc.Health.Care. Pub Date Free Form Feb Volume 41 Issue 2 Start Page 34 Other Pages 57 Notes LR: 20151119; CI: Copyright (c) 2011; JID: 101134613; 0 (Tobacco Smoke Pollution); 6M3C89ZY6R (Nicotine); 7U1EE4V452 (Carbon Monoxide); ppublish Place of Publication United States ISSN/ISBN 1538-3199; 1538-3199 Accession Number PMID: 21232693 Language eng SubFile Journal Article; IM DOI 10.1016/j.cppeds.2010.10.001 [doi] Output Language Unknown(0) PMID 21232693 Abstract Waterpipe tobacco smoking is a centuries old practice, influenced by cultural tradition in Eastern Mediterranean countries, the Middle East, and parts of Asia. It historically has been an activity enjoyed primarily by men. In the past 2 decades, however, this method of tobacco smoking has increased in popularity in other parts of the world, including the USA. Growing interest in this form of smoking can be traced, in part, to the advent of a flavored tobacco, called maassel. The combination of flavoring agents and the paraphernalia itself used in the smoking process, along with its mystic appeal, novelty, affordability, and the social atmosphere in which smoking often occurs, has made waterpipe smoking attractive to women as well as men, cigarette smokers and nonsmokers alike, and particular groups, including persons of college age and younger adolescents. Although waterpipe smoking is perceived by its new generation of users to be less addictive and hazardous to health than cigarette smoking, researchers draw diametrically opposed conclusions. Research demonstrates that numerous toxic agents, including carcinogens, heavy metals, other particulate matter, and high levels of nicotine, are efficiently delivered through waterpipes. Moreover, sidestream smoke exposes others in the vicinity of waterpipe smokers to the risk of respiratory diseases and other conditions. In addition, persons sharing waterpipe mouthpieces may share infectious agents as well. Waterpipe tobacco smoking has been declared a public health problem by the World Health Organization and other authorities. Recognition of the deleterious effects of waterpipe smoking has led to initial attempts to expand regulatory control. Because waterpipe tobacco is not directly burned in the smoking process, many existing control measures do not apply. Public health authorities should monitor waterpipe tobacco use carefully. Finally, pediatricians and other healthcare providers should discourage experimentation and continued use among their adolescent patients. Descriptors Links Book Title Database Publisher Mosby, Inc Data Source Authors Martinasek,M.P., McDermott,R.J., Martini,L. Original/Translated Title URL Date of Electronic PMCID Editors
Susceptibility to antifungal agents of Candida sp. and biofilm formation	2011	Katedra i Zaklad Mikrobiologii Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytet Mikolaja Kopernika w Toruniu.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Medycyna doswiadczalna i mikrobiologia Periodical, Abbrev. Med.Dosw.Mikrobiol. Pub Date Free Form Volume 63 Issue 2 Start Page 171 Other Pages 187 Notes JID: 0210575; 0 (Antifungal Agents); 0 (Biocompatible Materials); ppublish Place of Publication Poland ISSN/ISBN 0025-8601; 0025-8601 Accession Number PMID: 22184912 Language pol SubFile English Abstract; Journal Article; IM DOI Output Language Unknown(0) PMID 22184912 Abstract In recent years the increase in frequency of fungal infections with Candida sp. was noticed. These infections are connected with ability of Candida sp. to form biofilm on surfaces of biomaterials used in medicine. Furthermore fungal infections make serious therapeutic problems because ofbiofilm resistance to antifungal agents actually. The aim of the study was to evaluate the susceptibility to antifungal agents of Candida sp. and their ability to form biofilm on different biomaterials. 50 strains of Candida sp. isolated from patients of University Hospital No. 1 of dr A. Jurasz in Bydgoszcz were examined. API Candida (bioMerieux) tests were used to identify Candida sp. strains. The susceptibility of the yeast strains to antifungal agents was evaluated by ATB FUNGUS 2 INT (bioMerieux) tests. The susceptibility of examined strains to voriconazole, posaconazole, caspofungin and anidulafungin was assessed by means ofEtests (AB BIODISK) method employing drug concentrations from 0,002 to 32 microg/ml. All analysed strains were susceptible to amphotericin B and caspofungin. Biofilm formation on different biomaterials (silicon, latex, polychloride vinyl, polypropylene, nylon) was measured after 72 hour incubation at 37 degrees C. All examined yeasts formed biofilm on all analysed biomaterials. The highest number of strains formed biofilm on surface of polychloride vinyl: 23 (92,0%) by C. albicans strains and 24 (96,0%) Candida non-albicans strains. The lowest number of the strains formed biofilm on the surface of nylon: 12 (48,0%) of C. albicans strains and 9 (36,0%) of Candida non-albicans strains. The studied strains resistant to azoles and anidulafungin display stronger ability to form biofilm on surfaces of all analysed biomaterials. Descriptors Links Book Title Database Publisher Data Source Authors Ciok-Pater,E., Bialucha,A., Gospodarek,E., Ostafin,A. Original/Translated Title Lekowrazliwosc a zdolnosc tworzenia biofilmu przez Candida sp URL Date of Electronic PMCID Editors
Smoking among patients of selected specialist clinics of Miedzylesie Specialist Hospital in Warsaw	2011	Zaklad Pielegniarstwa Klinicznego Wydzialu Nauki o Zdrowiu Warszawskiego Uniwersytetu Medycznego. dpytka@interia.pl	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Przeglad lekarski Periodical, Abbrev. Przegl.Lek. Pub Date Free Form Volume 68 Issue 5 Start Page 243 Other Pages 247 Notes LR: 20151119; JID: 19840720R; 0 (Tobacco Smoke Pollution); ppublish Place of Publication Poland ISSN/ISBN 0033-2240; 0033-2240 Accession Number PMID: 21961410 Language pol SubFile English Abstract; Journal Article; IM DOI Output Language Unknown(0) PMID 21961410 Abstract The purpose of the study is to examine the issue of smoking among patients of selected clinics of the Miedzylesie Specialist Hospital in Warsaw, assessment of nicotine addiction of smokers and motivation to give up smoking. The survey was carried out in June and July 2009 after obtaining the consent of the Director of Miedzylesie Specialist Hospital in Warsaw. The survey was participated in by 100 patients of selected specialist clinics. The survey was carried out on the basis of a questionnaire consisting of 7 questions. Furthermore, the "Test of motivation to give up smoking" (Schneider's test) and the "Assessment of nicotine addiction level" (Fagerstrom's test), published in the "Consensus regarding recognition and treatment of nicotine addiction", were used. When processing data, the descriptive statistics were applied. Those surveyed included 53 former cigarette smokers 47 active smokers and. In the group of former smokers, 19 people still were exposed to passive smoking. In the past, the problem regarded 41 people. Thirty former smokers smoked cigarettes among non-smokers, including young children (18 people) and when pregnant and breastfeeding (2 people). Also 30 respondents smoked despite medical contraindications and bad conscience. For 27 people, expenditures on cigarettes constituted a considerable burden of their respective household budgets, and 20 said that it was a significant item in their expenditures. Smokers have been smoking cigarettes for 30 years, on average 20 cigarettes a day. Those patients began to smoke at the age of 20. Thirty one active smokers exposed other people to passive smoking and 38 respondents smoked cigarettes despite medical contraindications and with bad conscience. For 22 people, expenditures related to smoking are a considerable burden of the household budget and for 21 people, it is a significant expenditure. Almost one half of the patients smoke cigarettes although they should brake off smoking for medical reasons. Most of those surveyed (32 people) are motivated to brake off smoking. Those people are highly (13 people) and extremely (9 people) addicted to nicotine. Descriptors Links Book Title Database Publisher Data Source Authors Pytka,D., Doboszynska,A. Original/Translated Title Palenie tytoniu wsrod pacjentow wybranych poradni specjalistycznych Miedzyleskiego Szpitala Specjalistycznego w Warszawie URL Date of Electronic PMCID Editors
Association of six-minute walk distance (6MWD) with resting pulmonary function in patients with chronic obstructive pulmonary disease (COPD)	2011	Department of Respiratory Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan. pattypoti@hotmail.com	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Osaka city medical journal Periodical, Abbrev. Osaka City Med.J. Pub Date Free Form Jun Volume 57 Issue 1 Start Page 21 Other Pages 29 Notes JID: 0376413; ppublish Place of Publication Japan ISSN/ISBN 0030-6096; 0030-6096 Accession Number PMID: 22106764 Language eng SubFile Journal Article; IM DOI Output Language Unknown(0) PMID 22106764 Abstract BACKGROUND: The six-minute walk test (6MWT) is widely used for integrated assessment of patients with chronic obstructive pulmonary disease (COPD). However, little is known concerning which resting pulmonary function test measurements relate to six-minute walk distance (6MWD). METHODS: We retrospectively analyzed consecutive data of spirometry, lung volume analysis, and measurements of diffusing capacity of the lung for carbon monoxide (DLCO) and 6MWT from total of one-hundred and thirty patients with COPD. Univariate and multivariate analyses were performed to examine the relationships between 6MWD and variables. RESULTS: By linear regression analysis, 6MWD was significantly associated with age, weight, BMI, FEV1.0, FEV1.0 (% predicted), IC, TLC, IC/TLC, FEF25-75, DLCO (% predicted), and DLCO/VA. Stepwise multiple regression analysis revealed that age (r2 = 0.173; p Descriptors Links Book Title Database Publisher Data Source Authors Fujimoto,H., Asai,K., Watanabe,T., Kanazawa,H., Hirata,K. Original/Translated Title URL Date of Electronic PMCID Editors
Cigarette smoking and its association with overlapping gastroesophageal reflux disease, functional dyspepsia, or irritable bowel syndrome	2011	Department of Gastroenterology, Osaka City University Graduate School of Medicine, Japan. yasu@med.osaka-cu.ac.jp	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Internal medicine (Tokyo, Japan) Periodical, Abbrev. Intern.Med. Pub Date Free Form Volume 50 Issue 21 Start Page 2443 Other Pages 2447 Notes LR: 20151119; JID: 9204241; 2011/11/01 [epublish]; ppublish Place of Publication Japan ISSN/ISBN 1349-7235; 0918-2918 Accession Number PMID: 22041340 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI JST.JSTAGE/internalmedicine/50.6012 [pii] Output Language Unknown(0) PMID 22041340 Abstract BACKGROUND: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD), and irritable bowel syndrome (IBS) are common gastrointestinal diseases. Several studies have shown a significant occurrence of overlap among these 3 diseases. The purpose of this study was to examine the factors associated with such disease overlap in Japanese adults. METHODS: We performed a cross-sectional study on Japanese workers who visited a clinic for a routine health check-up and asked them to fill out a self-report questionnaire. GERD was defined as episodes of heartburn and/or acid regurgitation at least once a week, and the diagnosis of FD and IBS was based on Rome III criteria. A logistic regression model was used to identify risk factors, and odds ratio (OR) was calculated with 95% confidence intervals (CIs). RESULTS: Disease overlaps were found in 160 (6.0%) of the 2680 eligible subjects. Female gender was associated with GERD + IBS (OR=1.99; 95% CI, 1.06-3.75), and FD + IBS (OR=1.72; 95% CI, 1.03-2.85), and lower body mass index was negatively associated with FD + IBS (OR=0.54; 96% CI, 0.34-0.87). Cigarette smoking was a common factor associated with the overlaps: GERD + FD (OR=2.14; 95% CI, 1.22-3.76), GERD + IBS (OR=3.16; 95% CI, 1.75-3.71), FD + IBS (OR=2.26; 95% CI, 1.40-3.66), and GERD + FD + IBS (OR=4.08; 95% CI, 1.66-10.07). The associations between smoking habits and overlaps were stronger in smokers who smoked >/=1 pack per day as compared to those who smoked Descriptors Links Book Title Database Publisher Data Source Authors Fujiwara,Y., Kubo,M., Kohata,Y., Machida,H., Okazaki,H., Yamagami,H., Tanigawa,T., Watanabe,K., Watanabe,T., Tominaga,K., Arakawa,T. Original/Translated Title URL Date of Electronic 20111101 PMCID Editors
Effects of dissuasive packaging on young adult smokers	2011	Department of Marketing, University of Otago, PO Box 56, Dunedin, 9054, New Zealand. janet.hoek@otago.ac.nz	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form May Volume 20 Issue 3 Start Page 183 Other Pages 188 Notes JID: 9209612; 2010/10/21 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 20966135 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1136/tc.2010.037861 [doi] Output Language Unknown(0) PMID 20966135 Abstract BACKGROUND: Tobacco industry documents illustrate how packaging promotes smoking experimentation and reinforces existing smokers' behaviour. Plain packaging reduces the perceived attractiveness of smoking and creates an opportunity to introduce larger pictorial warnings that could promote cessation-linked behaviours. However, little is known about the effects such a combined policy measure would have on smokers' behaviour. METHODS: A 3 (warning size) 4 (branding level) plus control (completely plain pack) best-worst experiment was conducted via face-to-face interviews with 292 young adult smokers from a New Zealand provincial city. The Juster Scale was also used to estimate cessation-linked behaviours among participants. RESULTS: Of the 13 options tested, respondents were significantly less likely to choose those featuring fewer branding elements or larger health warnings. Options that featured more branding elements were still preferred even when they also featured a 50% health warning, but were significantly less likely to be chosen when they featured a 75% warning. Comparison of a control pack representing the status quo (branded with 30% front of pack warning) and a plain pack (with a 75% warning) revealed the latter would be significantly more likely to elicit cessation-related behaviours. CONCLUSIONS: Plain packs that feature large graphic health warnings are significantly more likely to promote cessation among young adult smokers than fully or partially branded packs. The findings support the introduction of plain packaging and suggest use of unbranded package space to feature larger health warnings would further promote cessation. Descriptors* Links Book Title Database Publisher Data Source Authors Hoek,J., Wong,C., Gendall,P., Louviere,J., Cong,K. Original/Translated Title URL Date of Electronic 20101021 PMCID Editors
A novel graphene nanosheets coated stainless steel fiber for microwave assisted headspace solid phase microextraction of organochlorine pesticides in aqueous samples followed by gas chromatography with electron capture detection	2011	Department of Chemistry, National Chung-Hsing University, Taichung 402, Taiwan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 28-Sep Volume 1218 Issue 39 Start Page 6861 Other Pages 6868 Notes CI: Copyright (c) 2011; JID: 9318488; 0 (Hydrocarbons, Chlorinated); 0 (Pesticides); 0 (Water Pollutants, Chemical); 12597-68-1 (Stainless Steel); 7782-42-5 (Graphite); 2011/04/15 [received]; 2011/08/08 [revised]; 2011/08/08 [accepted]; 2011/08/16 [aheado Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 21872868 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2011.08.019 [doi] Output Language Unknown(0) PMID 21872868 Abstract In this study, a novel graphene nanosheets (GNSs) coated solid phase microextraction (SPME) fiber was prepared by immobilizing microwave synthesized GNSs on a stainless steel wire. Microwave synthesized GNSs were verified by X-ray diffraction, field emission-scanning electron microscopy (FE-SEM) and transmission electron microscope (TEM). GNS-SPME fiber was characterized using FE-SEM and the results showed the GNS coating was homogeneous, porous, and highly adherent to the surface of the stainless steel fiber. The performance and feasibility of the GNS-SPME fiber was evaluated under one-step microwave assisted (MA) headspace (HS) SPME followed by gas chromatography with electron capture detection for five organochlorine pesticides (OCPs) in aqueous samples. Parameters influencing the extraction efficiency of MA-HS-GNS-SPME such as microwave irradiation power and time, pH, ionic strength, and desorption conditions were thoroughly examined. Under the optimized conditions, detection limits for the OCPs varied between 0.16 and 0.93 ng L(-1) and linear ranges varied between 1 and 1500 n gL(-1), with correlation coefficients ranging from 0.9984 to 0.9998, and RSDs in the range of 3.6-15.8% (n=5). In comparison with the commercial 100 mum polydimethylsiloxane fiber, the GNS coated fiber showed better extraction efficiency, higher mechanical and thermal stability (up to 290 degrees C), longer life span (over 250 times), and lower production cost. The method was successfully applied to the analysis of real water samples with recoveries ranged between 80.1 and 101.1% for river water samples. The results demonstrated that the developed MA-HS-GNS-SPME method was a simple, rapid, efficient pretreatment and environmentally friendly procedure for the analysis of OCPs in aqueous samples. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Ponnusamy,V.K., Jen,J.F. Original/Translated Title URL Date of Electronic 20110816 PMCID Editors
Measurement of fine particles and smoking activity in a statewide survey of 36 California Indian casinos	2011	Department of Civil and Environmental Engineering, Stanford University, Stanford, California 94305, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of exposure science & environmental epidemiology Periodical, Abbrev. J.Expo.Sci.Environ.Epidemiol. Pub Date Free Form Jan-Feb Volume 21 Issue 1 Start Page 31 Other Pages 41 Notes LR: 20141204; JID: 101262796; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); OID: NLM: PMC3007589; 2010/02/17 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1559-064X; 1559-0631 Accession Number PMID: 20160761 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1038/jes.2009.75 [doi] Output Language Unknown(0) PMID 20160761 Abstract Despite California's 1994 statewide smoking ban, exposure to secondhand smoke (SHS) continues in California's Indian casinos. Few data are available on exposure to airborne fine particles (PM(2).(5)) in casinos, especially on a statewide basis. We sought to measure PM(2).(5) concentrations in Indian casinos widely distributed across California, exploring differences due to casino size, separation of smoking and non-smoking areas, and area smoker density. A selection of 36 out of the 58 Indian casinos throughout California were each visited for 1-3 h on weekend or holiday evenings, using two or more concealed monitors to measure PM(2).(5) concentrations every 10 s. For each casino, the physical dimensions and the number of patrons and smokers were estimated. As a preliminary assessment of representativeness, we also measured eight casinos in Reno, NV. The average PM(2).(5) concentration for the smoking slot machine areas (63 mug/m(3)) was nine times as high as outdoors (7 mug/m(3)), whereas casino non-smoking restaurants (29 mug/m(3)) were four times as high. Levels in non-smoking slot machine areas varied: complete physical separation reduced concentrations almost to outdoor levels, but two other separation types had mean levels that were 13 and 29 mug/m(3), respectively, higher than outdoors. Elevated PM(2).(5) concentrations in casinos can be attributed primarily to SHS. Average PM(2).(5) concentrations during 0.5-1 h visits to smoking areas exceeded 35 mug/m(3) for 90% of the casino visits. Descriptors Links Book Title Database Publisher Data Source Authors Jiang,R.T., Cheng,K.C., Acevedo-Bolton,V., Klepeis,N.E., Repace,J.L., Ott,W.R., Hildemann,L.M. Original/Translated Title URL Date of Electronic 20100217 PMCID PMC3007589 Editors
The SCIDOTS Project: evidence of benefits of an integrated tobacco cessation intervention in tuberculosis care on treatment outcomes	2011	Clinical Pharmacy and Practice Section, College of Pharmacy, Qatar University, P.O. Box 2713, Doha, Qatar. aawaisu@qu.edu.qa	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Substance abuse treatment, prevention, and policy Periodical, Abbrev. Subst.Abuse Treat.Prev.Policy. Pub Date Free Form 23-Sep Volume 6 Issue Start Page 26 Other Pages 597X-6-26 Notes LR: 20150129; JID: 101258060; OID: NLM: PMC3196696; 2011/05/26 [received]; 2011/09/23 [accepted]; 2011/09/23 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1747-597X; 1747-597X Accession Number PMID: 21943384 Language eng SubFile Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; IM DOI 10.1186/1747-597X-6-26 [doi] Output Language Unknown(0) PMID 21943384 Abstract BACKGROUND: There is substantial evidence to support the association between tuberculosis (TB) and tobacco smoking and that the smoking-related immunological abnormalities in TB are reversible within six weeks of cessation. Therefore, connecting TB and tobacco cessation interventions may produce significant benefits and positively impact TB treatment outcomes. However, no study has extensively documented the evidence of benefits of such integration. SCIDOTS Project is a study from the context of a developing nation aimed to determine this. METHODS: An integrated TB-tobacco intervention was provided by trained TB directly observed therapy short-course (DOTS) providers at five chest clinics in Malaysia. The study was a prospective non-randomized controlled intervention using quasi-experimental design. Using Transtheoretical Model approach, 120 eligible participants who were current smokers at the time of TB diagnosis were assigned to either of two treatment groups: conventional TB DOTS plus smoking cessation intervention (integrated intervention or SCIDOTS group) or conventional TB DOTS alone (comparison or DOTS group). At baseline, newly diagnosed TB patients considering quitting smoking within the next 30 days were placed in the integrated intervention group, while those who were contemplating quitting were assigned to the comparison group. Eleven sessions of individualized cognitive behavioral therapy with or without nicotine replacement therapy were provided to each participant in the integrated intervention group. The impacts of the novel approach on biochemically validated smoking cessation and TB treatment outcomes were measured periodically as appropriate. RESULTS: A linear effect on both 7-day point prevalence abstinence and continuous abstinence was observed over time in the intervention group. At the end of 6 months, patients who received the integrated intervention had significantly higher rate of success in quitting smoking when compared with those who received the conventional TB treatment alone (77.5% vs. 8.7%; p Descriptors Links Book Title Database Publisher Data Source Authors Awaisu,A., Nik Mohamed,M.H., Mohamad Noordin,N., Abd Aziz,N., Syed Sulaiman,S.A., Muttalif,A.R., Ahmad Mahayiddin,A. Original/Translated Title URL Date of Electronic 20110923 PMCID PMC3196696 Editors

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