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Reactions to FDA-Proposed Graphic Warning Labels Affixed to U.S. Smokers' Cigarette Packs 2015 Health Communication Research Laboratory, Washington University in St. Louis, St. Louis, MO; amcqueen@dom.wustl.edu.; Health Communication Research Laboratory, Washington University in St. Louis, St. Louis, MO;; Health Communication Research Laboratory, W
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Jul
Volume
17
Issue
7
Start Page
784
Other Pages
795
Notes
LR: 20160701; CI: (c) The Author 2015; GR: P50CA95815-09S1/CA/NCI NIH HHS/United States; JID: 9815751; OID: NLM: PMC4542680; 2014/01/31 [received]; 2014/12/15 [accepted]; 2015/01/14 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25589676
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/ntr/ntu339 [doi]
Output Language
Unknown(0)
PMID
25589676
Abstract
INTRODUCTION: Graphic warning labels have been shown to be more effective than text-only labels in increasing attention and perceived health risks, but most U.S. studies have involved single exposures in laboratory or Internet settings. METHODS: We recruited a convenience sample (N = 202) of U.S. adult smokers from population subgroups with higher rates of smoking and smoking-related deaths who had participated in a larger survey about graphic warning labels. Participants were randomized to get 1 of 9 graphic + text labels or a text-only label. Research staff affixed a warning label sticker to participants' cigarette pack(s) at enrollment. Color graphic labels covered slightly more than the lower half of packs. Black and white labels of current U.S. text-only warnings covered the existing side warning to prompt attention to the label (i.e., attention control). Participants received extra stickers of the same label for subsequent packs, and completed 3 telephone interviews in 1 week. RESULTS: Participants reported low avoidance (
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
McQueen,A., Kreuter,M.W., Boyum,S., Thompson,V.S., Caburnay,C.A., Waters,E.A., Kaphingst,K.A., Rath,S., Fu,Q.
Original/Translated Title
URL
Date of Electronic
20150114
PMCID
PMC4542680
Editors
Effectiveness of text versus pictorial health warning labels and predictors of support for plain packaging of tobacco products within the European Union 2015 Center for Global Tobacco Control, Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Mass., USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
European addiction research
Periodical, Abbrev.
Eur.Addict.Res.
Pub Date Free Form
Volume
21
Issue
1
Start Page
47
Other Pages
52
Notes
LR: 20151119; JID: 9502920; 2014/04/07 [received]; 2014/07/17 [accepted]; 2014/11/11 [aheadofprint]; ppublish
Place of Publication
Switzerland
ISSN/ISBN
1421-9891; 1022-6877
Accession Number
PMID: 25402440
Language
eng
SubFile
Comparative Study; Journal Article; IM
DOI
10.1159/000366019 [doi]
Output Language
Unknown(0)
PMID
25402440
Abstract
BACKGROUND: Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the European Union (EU). METHODS: The Special Eurobarometer 385 survey was analyzed for 26,566 adults from 27 EU countries in 2012. The self-reported impact of warning labels (text or pictorial) and determinants of EU-wide support for plain packaging were assessed using multivariate logistic regression. RESULTS: Current smokers in countries where cigarette pictorial warnings were implemented had higher odds of reporting that health warning labels had any effect on their smoking behavior (making a quit attempt or reducing number of cigarettes smoked per day) compared to respondents in countries with text-only warning labels (adjusted odds ratio, aOR = 1.31; 95% confidence interval, 95% CI: 1.10-1.56). Population support for plain packaging of tobacco packs was higher in countries where cigarette pictorial warnings already existed (aOR = 1.17; 95% CI: 1.07-1.28). CONCLUSIONS: These findings indicate that the implementation of pictorial warnings at an EU level may have a positive behavioral impact among smokers and pave the way for population support for plain packaging in the EU.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Agaku,I.T., Filippidis,F.T., Vardavas,C.I.
Original/Translated Title
URL
Date of Electronic
20141111
PMCID
Editors
Deficiencies in public understanding about tobacco harm reduction: results from a United States national survey 2015 Department of Community Health and Health Behavior, University at Buffalo, State University of New York, School of Public Health and Health Professions, 3425 Main Street, Buffalo, NY, 14214, USA. mtk8@buffalo.edu.; Department of Community Health and Healt
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Harm reduction journal
Periodical, Abbrev.
Harm Reduct J.
Pub Date Free Form
2-Jul
Volume
12
Issue
Start Page
21
Other Pages
015-0055-0
Notes
LR: 20150707; JID: 101153624; OID: NLM: PMC4487951; 2015/03/13 [received]; 2015/06/25 [accepted]; 2015/07/02 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1477-7517; 1477-7517
Accession Number
PMID: 26135116
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1186/s12954-015-0055-0 [doi]
Output Language
Unknown(0)
PMID
26135116
Abstract
BACKGROUND: Tobacco products differ in their relative health harms. The need for educating consumers about such harms is growing as different tobacco products enter the marketplace and as the FDA moves to regulate and educate the public about different products. However, little is known about the patterns of the public's knowledge of relative harms. METHODS: Data were analyzed from the Health Information National Trends Survey (HINTS) 4 Cycle 2, a population-representative survey of US adults conducted between October 2012 and January 2013 (N = 3630). Participants reported their perceptions of the relative risks of e-cigarettes, smokeless tobacco, and different types of cigarettes compared to "traditional" cigarettes. Relative risk perceptions for each product type, as well as the consistency and accuracy of harm reduction beliefs, were analyzed. RESULTS: About 65% of the respondents accurately reported that no cigarettes were less harmful than any others. Slightly more than half of U.S. adults perceived e-cigarettes to be safer than regular cigarettes, a belief in line with current scientific evidence. By contrast, only 9% of respondents perceived some smokeless tobacco products to be safer, a belief strongly supported by the evidence. Only 3.5% of respondents had patterns of relative risk perceptions in line with current scientific evidence for all three modalities. CONCLUSIONS: The discrepancy between current evidence and public perceptions of relative risk of various tobacco/nicotine products was marked; for most tobacco types, a large proportion of the population held inaccurate harm reduction beliefs. Although there was substantial awareness that no cigarettes were safer than any other cigarettes, there could be benefits from increasing the percentage of the public that appreciates this fact, especially among current smokers. Given the potential benefits of tobacco risk reduction strategies, public health education efforts to increase understanding of basic harm reduction principles are needed to address these misperceptions.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Kiviniemi,M.T., Kozlowski,L.T.
Original/Translated Title
URL
Date of Electronic
20150702
PMCID
PMC4487951
Editors
Determinants and prevalence of e-cigarette use throughout the European Union: a secondary analysis of 26 566 youth and adults from 27 Countries 2015 Clinic of Social and Family Medicine, School of Medicine, University of Crete, Heraklion, Greece Department of Social and Behavioral Sciences, Center for Global Tobacco Control, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of S
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Sep
Volume
24
Issue
5
Start Page
442
Other Pages
448
Notes
CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; JID: 9209612; OTO: NOTNLM; 2013/10/16 [received]; 2014/04/02 [accep
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 24935441
Language
eng
SubFile
Journal Article; IM
DOI
10.1136/tobaccocontrol-2013-051394 [doi]
Output Language
Unknown(0)
PMID
24935441
Abstract
OBJECTIVE: This study assessed the prevalence and determinants of e-cigarette use among persons aged >/=15 years in 27 European Union (EU) member countries during 2012. METHODS: The 2012 Eurobarometer 385 (77.1) survey was analysed for n=26 566 respondents. Knowledge, perception of harm, and determinants of e-cigarettes use were assessed, while separate regression analyses among current (n=7352) and former cigarette smokers (n=5782) were performed. National estimates of the number of e-cigarette users were also extrapolated. RESULTS: 20.3% of current smokers, 4.7% of ex-smokers, and 1.2% of never cigarette smokers in the EU reported having ever used an e-cigarette (overall approximately 29.3 million adults). Among smokers, ever e-cigarette use was more likely among 15-24-year-olds (aOR 3.13, 95% CI 2.22 to 4.54) and 25-39-year-olds (aOR 2.00, 95% CI 1.47 to 2.78) in comparison to older smokers, and among those who smoked 6-10 cigarettes/day (aOR 1.53, 95% CI 1.10 to 2.13) or 11-20 cigarettes/day (aOR 2.07, 95% CI 1.52 to 2.81) in comparison to very light smokers (=5 cigarettes/day). Moreover, e-cigarette use was more likely among smokers who had made a past year quit attempt (aOR 2.08, 95% CI 1.67 to 2.58). E-cigarette use among ex-smokers was associated only with the respondents' age, with younger ex-smokers being more likely to have ever used an e-cigarette. CONCLUSIONS: A substantial number of EU adults have ever used e-cigarettes. Ever users were more likely to be younger, current smokers, or past-year quit attempters. These findings underscore the need to evaluate the potential long term impact of e-cigarette use on consumer health, cessation and nicotine addiction and formulate a European framework for e-cigarette regulation within the revised EU Tobacco Product Directive.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Vardavas,C.I., Filippidis,F.T., Agaku,I.T.
Original/Translated Title
URL
Date of Electronic
20140616
PMCID
Editors
E-cigarette Use Among High School and Middle School Adolescents in Connecticut 2015 Department of Psychiatry, Yale School of Medicine, New Haven, CT; Suchitra.krishnan-sarin@yale.edu.; Department of Psychiatry, Yale School of Medicine, New Haven, CT;; Department of Pediatrics, Yale School of Medicine, New Haven, CT.; Department of Psychi
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Jul
Volume
17
Issue
7
Start Page
810
Other Pages
818
Notes
LR: 20160701; CI: (c) The Author 2014; GR: P50DA009241/DA/NIDA NIH HHS/United States; JID: 9815751; 0 (Flavoring Agents); OID: NLM: PMC4674435; 2014/07/08 [received]; 2014/11/03 [accepted]; 2014/11/09 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25385873
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1093/ntr/ntu243 [doi]
Output Language
Unknown(0)
PMID
25385873
Abstract
INTRODUCTION: There is limited evidence on electronic cigarette (e-cigarette) use among U.S. adolescents. METHODS: Cross-sectional, anonymous surveys conducted in 4 high schools (HS; n = 3,614) and 2 middle schools (MS; n = 1,166) in Connecticut in November 2013 examined e-cigarette awareness, use patterns, susceptibility to future use, preferences, product components used (battery type, nicotine content, flavors), and sources of marketing and access. RESULTS: High rates of awareness (MS: 84.3%; HS: 92.0%) and of lifetime (3.5% MS, 25.2 % HS) and current (1.5% MS, 12% HS) use of e-cigarettes was observed. Among those who had not tried e-cigarettes, 26.4% of MS and 31.7% of HS students reported being susceptible to future use. Males (OR = 1.70, p
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Krishnan-Sarin,S., Morean,M.E., Camenga,D.R., Cavallo,D.A., Kong,G.
Original/Translated Title
URL
Date of Electronic
20141109
PMCID
PMC4674435
Editors
Prevalence and reasons for use of electronic cigarettes among smokers: Findings from the International Tobacco Control (ITC) Netherlands Survey 2015 Department of Health Promotion, Maastricht University (CAPHRI), P. Debyeplein 1, 6229 HA Maastricht, The Netherlands. Electronic address: Karin.Hummel@maastrichtuniversity.nl.; Department of Health Promotion, Maastricht University (CAPHRI), P. Debyeplein
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The International journal on drug policy
Periodical, Abbrev.
Int.J.Drug Policy
Pub Date Free Form
Jun
Volume
26
Issue
6
Start Page
601
Other Pages
608
Notes
CI: Copyright (c) 2014; JID: 9014759; OTO: NOTNLM; 2014/08/04 [received]; 2014/11/28 [revised]; 2014/12/09 [accepted]; 2014/12/17 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1873-4758; 0955-3959
Accession Number
PMID: 25582280
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.drugpo.2014.12.009 [doi]
Output Language
Unknown(0)
PMID
25582280
Abstract
BACKGROUND: Not much is known about how people in the Netherlands respond to electronic cigarettes (e-cigarettes); how many know about them, which people try them, keep using them and why, and what are changes over time regarding awareness and use? METHODS: We used samples of smokers aged 15 years and older from 2008 (n=1820), 2010 (n=1702), 2013 (n=1530), and 2014 (n=1550) as part of the International Tobacco Control (ITC) Netherlands Survey. Reasons for use and characteristics of smokers were examined using the sample from 2014. Logistic regression analyses were conducted to evaluate the associations between smoking-related variables with ever trying e-cigarettes and current e-cigarette use. RESULTS: In 2014, 91.4% of Dutch smokers reported being aware of e-cigarettes (97.1% in 2008, 89.2% in 2010, and 85.5% in 2013), 40.0% reported having ever tried them (13.4% in 2008, 14.5% in 2010, and 19.6% in 2013), and 15.9% were currently using them (4.0% in 2008, 1% in 2010, and 3.9% in 2013). The main reason given for using e-cigarettes was to reduce the number of regular cigarettes smoked per day (79%). Ever trying e-cigarettes among those aware of e-cigarettes was associated with being young, smoking more regular cigarettes per day, having made a quit attempt in the last year, having used smoking cessation pharmacotherapy in the last year, and reporting high awareness of the price of regular cigarettes. Smokers who kept using e-cigarettes had a higher educational background, had higher harm awareness for the health of others, and were less likely to have a total smoking ban at home. CONCLUSION: E-cigarettes are increasingly used by Dutch smokers. Commonly endorsed motivations for current e-cigarette use were to reduce tobacco smoking and because e-cigarettes are considered to be less harmful than tobacco cigarettes.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Hummel,K., Hoving,C., Nagelhout,G.E., de Vries,H., van den Putte,B., Candel,M.J., Borland,R., Willemsen,M.C.
Original/Translated Title
URL
Date of Electronic
20141217
PMCID
Editors
Adolescents' and Young Adults' Perceptions of Electronic Cigarettes for Smoking Cessation: A Focus Group Study 2015 Department of Pediatrics, Yale School of Medicine, New Haven, CT;; Department of Psychiatry, Yale School of Medicine, New Haven, CT;; Department of Psychiatry, Yale School of Medicine, New Haven, CT;; Department of Psychiatry, Yale School of Medicine, New
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Oct
Volume
17
Issue
10
Start Page
1235
Other Pages
1241
Notes
LR: 20160205; CI: (c) The Author 2015; GR: 1K12DA033012-01A1/DA/NIDA NIH HHS/United States; GR: P50DA009241/DA/NIDA NIH HHS/United States; GR: T32 DA019426/DA/NIDA NIH HHS/United States; GR: T32DA019426/DA/NIDA NIH HHS/United States; JID: 9815751; 6M3C89Z
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25646346
Language
eng
SubFile
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; IM
DOI
10.1093/ntr/ntv020 [doi]
Output Language
Unknown(0)
PMID
25646346
Abstract
INTRODUCTION: Research has shown that adults perceive that electronic cigarettes (e-cigarettes) are effective for smoking cessation, yet little is known about adolescents and young adults' perceptions of e-cigarettes for quitting cigarette smoking. This study describes middle, high school, and college students' beliefs about, and experiences with, e-cigarettes for cigarette smoking cessation. METHODS: We conducted 18 focus groups (n = 127) with male and female cigarette smokers and nonsmokers in 2 public colleges, 2 high schools, and 1 middle school in Connecticut between November 2012 and April 2013. Participants discussed cigarette smoking cessation in relation to e-cigarettes. Verbatim transcripts were analyzed using thematic analysis. RESULTS: All participants, regardless of age and smoking status, were aware that e-cigarettes could be used for smoking cessation. College and high school participants described different methods of how e-cigarettes could be used for smoking cessation: (a) nicotine reduction followed by cessation; (b) cigarette reduction/dual use; and (c) long-term exclusive e-cigarette use. However, overall, participants did not perceive that e-cigarette use led to successful quitting experiences. Participants described positive attributes (maintenance of smoking actions, "healthier" alternative to cigarettes, and parental approval) and negative attributes (persistence of craving, maintenance of addiction) of e-cigarettes for cessation. Some college students expressed distrust of marketing of e-cigarettes for smoking cessation. CONCLUSIONS: Adolescent and young adult smokers and nonsmokers perceive that there are several methods of using e-cigarettes for quitting and are aware of both positive and negative aspects of the product. Future research is needed to determine the role of e-cigarettes for smoking cessation in this population.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Camenga,D.R., Cavallo,D.A., Kong,G., Morean,M.E., Connell,C.M., Simon,P., Bulmer,S.M., Krishnan-Sarin,S.
Original/Translated Title
URL
Date of Electronic
20150202
PMCID
PMC4607731
Editors
Biodiversity and gamma-aminobutyric acid production by lactic acid bacteria isolated from traditional alpine raw cow's milk cheeses 2015 Research and Innovation Centre, Department of Food Quality and Nutrition, Fondazione Edmund Mach (FEM), Via E. Mach 1, 38010 San Michele all'Adige, Italy.; Research and Innovation Centre, Department of Food Quality and Nutrition, Fondazione Edmund Mach (F
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BioMed research international
Periodical, Abbrev.
Biomed.Res.Int.
Pub Date Free Form
Volume
2015
Issue
Start Page
625740
Other Pages
Notes
LR: 20150327; JID: 101600173; 33X04XA5AT (Lactic Acid); 56-12-2 (gamma-Aminobutyric Acid); OID: NLM: PMC4352725; 2014/06/17 [received]; 2014/09/04 [revised]; 2014/10/02 [accepted]; 2015/02/23 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
2314-6141
Accession Number
PMID: 25802859
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1155/2015/625740 [doi]
Output Language
Unknown(0)
PMID
25802859
Abstract
"Nostrano-cheeses" are traditional alpine cheeses made from raw cow's milk in Trentino-Alto Adige, Italy. This study identified lactic acid bacteria (LAB) developing during maturation of "Nostrano-cheeses" and evaluated their potential to produce gamma-aminobutyric acid (GABA), an immunologically active compound and neurotransmitter. Cheese samples were collected on six cheese-making days, in three dairy factories located in different areas of Trentino and at different stages of cheese ripening (24 h, 15 days, and 1, 2, 3, 6, and 8 months). A total of 1,059 LAB isolates were screened using Random Amplified Polymorphic DNA-PCR (RAPD-PCR) and differentiated into 583 clusters. LAB strains from dominant clusters (n = 97) were genetically identified to species level by partial 16S rRNA gene sequencing. LAB species most frequently isolated were Lactobacillus paracasei, Streptococcus thermophilus, and Leuconostoc mesenteroides. The 97 dominant clusters were also characterized for their ability in producing GABA by high-performance liquid chromatography (HPLC). About 71% of the dominant bacteria clusters evolving during cheeses ripening were able to produce GABA. Most GABA producers were Lactobacillus paracasei but other GABA producing species included Lactococcus lactis, Lactobacillus plantarum, Lactobacillus rhamnosus, Pediococcus pentosaceus, and Streptococcus thermophilus. No Enterococcus faecalis or Sc. macedonicus isolates produced GABA. The isolate producing the highest amount of GABA (80.0+/-2.7 mg/kg) was a Sc. thermophilus.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Franciosi,E., Carafa,I., Nardin,T., Schiavon,S., Poznanski,E., Cavazza,A., Larcher,R., Tuohy,K.M.
Original/Translated Title
URL
Date of Electronic
20150223
PMCID
PMC4352725
Editors
Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma 2015 Division of Gastroenterology and Hepatology, Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, CB#7080, Chapel Hill, NC 27599-7080, USA.; Division of Digestive and
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Gastroenterology clinics of North America
Periodical, Abbrev.
Gastroenterol.Clin.North Am.
Pub Date Free Form
Jun
Volume
44
Issue
2
Start Page
203
Other Pages
231
Notes
LR: 20160601; CI: Copyright (c) 2015; GR: K24 DK100548/DK/NIDDK NIH HHS/United States; GR: K24DK100548/DK/NIDDK NIH HHS/United States; GR: T32 DK007634/DK/NIDDK NIH HHS/United States; GR: T32 DK07634/DK/NIDDK NIH HHS/United States; JID: 8706257; 0 (Biomar
Place of Publication
United States
ISSN/ISBN
1558-1942; 0889-8553
Accession Number
PMID: 26021191
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Review; IM
DOI
10.1016/j.gtc.2015.02.001 [doi]
Output Language
Unknown(0)
PMID
26021191
Abstract
Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC), a disease with increasing burden in the Western world, especially in white men. Risk factors for BE include obesity, tobacco smoking, and gastroesophageal reflux disease (GERD). EAC is the most common form of esophageal cancer in the United States. Risk factors include GERD, tobacco smoking, and obesity, whereas nonsteroidal antiinflammatory drugs and statins may be protective. Factors predicting progression from nondysplastic BE to EAC include dysplastic changes on esophageal histology and length of the involved BE segment. Biomarkers have shown promise, but none are approved for clinical use.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Runge,T.M., Abrams,J.A., Shaheen,N.J.
Original/Translated Title
URL
Date of Electronic
20150409
PMCID
PMC4449458
Editors
Optimization of ultrasonic-assisted extraction for determination of polycyclic aromatic hydrocarbons in biochar-based fertilizer by gas chromatography-mass spectrometry 2015 Department of Environment and Resource, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Analytical and bioanalytical chemistry
Periodical, Abbrev.
Anal.Bioanal Chem.
Pub Date Free Form
Aug
Volume
407
Issue
20
Start Page
6149
Other Pages
6157
Notes
LR: 20160512; JID: 101134327; 0 (Fertilizers); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Solvents); 0 (biochar); 16291-96-6 (Charcoal); 2015/02/06 [received]; 2015/05/19 [accepted]; 2015/04/11 [revised]; 2015/06/06 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1618-2650; 1618-2642
Accession Number
PMID: 26048058
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Validation Studies; IM
DOI
10.1007/s00216-015-8790-3 [doi]
Output Language
Unknown(0)
PMID
26048058
Abstract
Application of biochar-based fertilizers is increasingly being considered for its potential agronomic and environmental benefits. However, biochar may contain residues of polycyclic aromatic hydrocarbons (PAHs) as a result of its production by pyrolysis. The strong adsorption of PAHs to biochar makes extraction and analysis of biochar-based fertilizers difficult. This study optimizes the extraction of PAHs in biochar-based fertilizer samples by using an ultrasonic bath for quantification by gas chromatography-mass spectrometry. Among 12 solvents, acetone-cyclohexane (1:1) mixture was selected as the optimum solvent for extraction. Three variables affecting the extraction were studied by Box-Behnken design. The optimum conditions were 57 degrees C extraction temperature, 81 min extraction time, and two extraction cycles, which were validated by assessing the linearity of analysis, LOD, LOQ, recovery, and levels of PAHs in real biochar-based fertilizer samples. Results revealed that the 16 U.S. EPA PAHs had good linearity, with squared correlation coefficients greater than 0.99. LODs were low, ranging from 2.2 ng g(-1) (acenaphthene) to 23.55 ng g(-1) (indeno[1,2,3-cd]perylene), and LOQs varied from 7.51 ng g(-1) to 78.49 ng g(-1). The recoveries of 16 individual PAHs from the three biochar-based fertilizer samples were 81.8-109.4 %. Graphical Abstract Use of RSM to optimize UAE for extraction of the PAHs in biochar-based fertilizer.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Chen,P., Sun,M., Zhu,Z., Zhang,J., Shen,G.
Original/Translated Title
URL
Date of Electronic
20150606
PMCID
Editors