WTS database

Title	Pub Year Sort ascending	Author	SearchLink
Nursing research in community-based approaches to reduce exposure to secondhand smoke	2009	University of Kentucky College of Nursing, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Annual Review of Nursing Research Periodical, Abbrev. Annu.Rev.Nurs.Res. Pub Date Free Form Volume 27 Issue Start Page 365 Other Pages 391 Notes JID: 8406387; 0 (Tobacco Smoke Pollution); RF: 116; ppublish Place of Publication United States ISSN/ISBN 0739-6686; 0739-6686 Accession Number PMID: 20192112 Language eng SubFile Journal Article; Review; IM; N DOI Output Language Unknown(0) PMID 20192112 Abstract Secondhand smoke (SHS) is the third leading cause of preventable death in the United States and a major source of indoor air pollution, accounting for an estimated 53,000 deaths per year among nonsmokers. Secondhand smoke exposure varies by gender, race/ethnicity, and socioeconomic status. The most effective public health intervention to reduce SHS exposure is to implement and enforce smoke-free workplace policies that protect entire populations including all workers regardless of occupation, race/ethnicity, gender, age, and socioeconomic status. This chapter summarizes community and population-based nursing research to reduce SHS exposure. Most of the nursing research in this area has been policy outcome studies, documenting improvement in indoor air quality, worker's health, public opinion, and reduction in Emergency Department visits for asthma, acute myocardial infarction among women, and adult smoking prevalence. These findings suggest a differential health effect by strength of law. Further, smoke-free laws do not harm business or employee turnover, nor are revenues from charitable gaming affected. Additionally, smoke-free laws may eventually have a positive effect on cessation among adults. There is emerging nursing science exploring the link between SHS exposure to nicotine and tobacco dependence, suggesting one reason that SHS reduction is a quit smoking strategy. Other nursing research studies address community readiness for smoke-free policy, and examine factors that build capacity for smoke-free policy. Emerging trends in the field include tobacco free health care and college campuses. A growing body of nursing research provides an excellent opportunity to conduct and participate in community and population-based research to reduce SHS exposure for both vulnerable populations and society at large. Descriptors Attitude to Health, Consumer Participation, Environmental Exposure/adverse effects/prevention & control, Health Promotion/organization & administration, Humans, Nursing Research, Public Policy, Smoking/legislation & jurisprudence/prevention & control, Tobacco Smoke Pollution/adverse effects/prevention & control, United States, Workplace Links Book Title Database Publisher Data Source Authors Hahn,E. J., Ashford,K. B., Okoli,C. T., Rayens,M. K., Ridner,S. L., York,N. L. Original/Translated Title URL Date of Electronic PMCID Editors
Relapse prevention interventions for smoking cessation	2009	Wolfson Institute of Preventive Medicine, Queen Mary's School of Medicine and Dentistry, Turner Street, London, UK, E1 2AD.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Cochrane database of systematic reviews Periodical, Abbrev. Cochrane Database Syst.Rev. Pub Date Free Form 21-Jan Volume (1):CD003999. doi Issue 1 Start Page CD003999 Other Pages Notes LR: 20151119; JID: 100909747; 0 (Chewing Gum); 0 (Nicotinic Agonists); 6M3C89ZY6R (Nicotine); CIN: Ann Intern Med. 2009 Jul 21;151(2):JC1-11. PMID: 19620155; UIN: Cochrane Database Syst Rev. 2013;8:CD003999. PMID: 23963584; RF: 93; epublish Place of Publication England ISSN/ISBN 1469-493X; 1361-6137 Accession Number PMID: 19160228 Language eng SubFile Journal Article; Meta-Analysis; Review; IM DOI 10.1002/14651858.CD003999.pub3 [doi] Output Language Unknown(0) PMID 19160228 Abstract BACKGROUND: A number of treatments can help smokers make a successful quit attempt, but many initially successful quitters relapse over time. Several interventions were proposed to help prevent relapse. OBJECTIVES: To assess whether specific interventions for relapse prevention reduce the proportion of recent quitters who return to smoking. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register in August 2008 for studies mentioning relapse prevention or maintenance in title, abstracts or keywords. SELECTION CRITERIA: Randomized or quasi-randomized controlled trials of relapse prevention interventions with a minimum follow up of six months. We included smokers who quit on their own, or were undergoing enforced abstinence, or who were participating in treatment programmes. We included trials that compared relapse prevention interventions to a no intervention control, or that compared a cessation programme with additional relapse prevention components to a cessation programme alone. DATA COLLECTION AND ANALYSIS: Studies were screened and data extracted by one author and checked by a second. Disagreements were resolved by discussion or referral to a third author. MAIN RESULTS: Fifty-four studies met inclusion criteria, but were heterogeneous in terms of populations and interventions. We considered 36 studies that randomized abstainers separately from studies that randomized participants prior to their quit date.Looking at studies of behavioural interventions which randomised abstainers, we detected no benefit of brief and 'skills-based' relapse prevention methods for women who had quit smoking due to pregnancy, or for smokers undergoing a period of enforced abstinence during hospitalisation or military training. We also failed to detect significant effects of behavioural interventions in trials in unselected groups of smokers who had quit on their own or with a formal programme. Amongst trials randomising smokers prior to their quit date and evaluating the effect of additional relapse prevention components we also found no evidence of benefit of behavioural interventions in any subgroup. Overall, providing training in skills thought to be needed for relapse avoidance did not reduce relapse, but most studies did not use experimental designs best suited to the task, and had limited power to detect expected small differences between interventions. For pharmacological interventions, extended treatment with varenicline significantly reduced relapse in one trial (risk ratio 1.18, 95% confidence interval 1.03 to 1.36). Pooling of five studies of extended treatment with bupropion failed to detect a significant effect (risk ratio 1.17; 95% confidence interval 0.99 to 1.39). Two small trials of oral nicotine replacement treatment (NRT) failed to detect an effect but treatment compliance was low and in two other trials of oral NRT randomizing short-term abstainers there was a significant effect of intervention. AUTHORS' CONCLUSIONS: At the moment there is insufficient evidence to support the use of any specific behavioural intervention for helping smokers who have successfully quit for a short time to avoid relapse. The verdict is strongest for interventions focusing on identifying and resolving tempting situations, as most studies were concerned with these. There is little research available regarding other behavioural approaches. Extended treatment with varenicline may prevent relapse. Extended treatment with bupropion is unlikely to have a clinically important effect. Studies of extended treatment with nicotine replacement are needed. Descriptors Behavior Therapy, Chewing Gum, Female, Humans, Male, Nicotine/therapeutic use, Nicotinic Agonists, Pregnancy, Randomized Controlled Trials as Topic, Secondary Prevention, Smoking/prevention & control, Smoking Cessation/methods Links Book Title Database Publisher Data Source Authors Hajek,P., Stead,L. F., West,R., Jarvis,M., Lancaster,T. Original/Translated Title URL Date of Electronic 20090121 PMCID Editors
Global patterns of nicotine and tobacco consumption	2009		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Handb Exp Pharmacol Periodical, Abbrev. Handb.Exp.Pharmacol. Pub Date Free Form Volume Issue 192 Start Page 3 Other Pages 28 Notes ID: 19184644 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract Humans consume tobacco in dozens of guises, all of which are toxic; globally, a tenth of deaths among adults are caused by tobacco. Tobacco may be combusted (e.g., cigarettes, bidis, kreteks); heated (e.g., waterpipes, hookah, nargile); or taken orally or nasally (e.g., snuff, betel quid, chewing tobacco). The predominant forms vary among cultures, but the use of cigarettes has grown most dramatically in the past century. While smoking rates among women are comparable to those among men in Europe and North America, in other regions the rate is ten or more times higher among men; this gender gap is closing among young people. Per capita tobacco use in the USA doubled in the first half of the twentieth century, and has since declined to less than the 1900 levels. While cigarettes were only 2% of tobacco consumed in the USA in 1900 (half was chewing tobacco) 50 years later they were over 80%. A similar increase in tobacco consumption, and a shift to cigarettes, has been occurring globally, with a concomitant increase in tobacco-related death and disease that is not expected to peak for another two decades. Descriptors Smoking/epidemiology, Tobacco Use Disorder/history, Tobacco, Adolescent, Age Distribution, History, 15th Century, History, 16th Century, History, 17th Century, History, 20th Century, History, 21st Century, History, Ancient, History, Medieval, Humans, Sex Distribution, Smoking/history, Tobacco/adverse effects, Tobacco Use Disorder/epidemiology, Tobacco, Smokeless/adverse effects, Tobacco, Smokeless/history Links http://dx.doi.org/10.1007/978-3-540-69248-5_1 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Hammond,S. K. Original/Translated Title URL Date of Electronic PMCID Editors
Commercial polymeric fiber as sorbent for solid-phase microextraction combined with high-performance liquid chromatography for the determination of polycyclic aromatic hydrocarbons in water	2009	Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 30-Oct Volume 1216 Issue 44 Start Page 7520 Other Pages 7526 Notes JID: 9318488; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Polymers); 0 (Water Pollutants, Chemical); 2008/12/30 [received]; 2009/08/07 [revised]; 2009/09/09 [accepted]; 2009/09/12 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 19786278 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2009.09.019 [doi] Output Language Unknown(0) PMID 19786278 Abstract A novel microextraction method making use of commercial polymer fiber as sorbent, coupled with high-performance liquid chromatography-fluorescence detection for the determination of polycyclic aromatic hydrocarbons (PAHs) in water has been developed. In this technique, the extraction device was simply a length (8 cm) of a strand of commercial polymer fiber, Kevlar (each strand consisted of 1000 filaments, each of diameter ca. 9.23 microm), that was allowed to tumble freely in the aqueous sample solution during extraction. The extracted analytes were desorbed ultrasonically before the extract was injected into HPLC system for analysis. Extraction parameters such as extraction time, desorption time, type of desorption solvent and sample volume were optimized. Each fiber could be used for up to 50 extractions and the method showed good precision, reproducibility and linear response within a concentration range 0.05-5.00 microg L(-1) with correlation coefficients of up to 0.9998. Limits of detection between 0.4 and 4.4 ng L(-1) for seven PAHs could be achieved. The relative standard deviations (n=3) of this technique were between 2.9% and 12.1%. Descriptors Chromatography, High Pressure Liquid/methods, Microscopy, Electron, Scanning, Polycyclic Hydrocarbons, Aromatic/analysis, Polymers/analysis, Solid Phase Microextraction/methods, Water Pollutants, Chemical/analysis Links Book Title Database Publisher Data Source Authors Hii,T. M., Basheer,C., Lee,H. K. Original/Translated Title URL Date of Electronic 20090912 PMCID Editors
Analysis of the gastrointestinal symptoms of uninvestigated dyspepsia and irritable bowel syndrome	2009	Department of Endoscopic Center, Hyogo College of Medicine, Nishinomiya, Japan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Gut and liver Periodical, Abbrev. Gut Liver Pub Date Free Form Sep Volume 3 Issue 3 Start Page 192 Other Pages 196 Notes LR: 20131113; JID: 101316452; OID: NLM: PMC2852717; OTO: NOTNLM; 2009/05/28 [received]; 2009/07/05 [accepted]; 2009/09/30 [epublish]; ppublish Place of Publication Korea (South) ISSN/ISBN 2005-1212; 1976-2283 Accession Number PMID: 20431745 Language eng SubFile Journal Article DOI 10.5009/gnl.2009.3.3.192 [doi] Output Language Unknown(0) PMID 20431745 Abstract BACKGROUND/AIMS: Epidemiological studies suggest that there is a considerable overlap between functional dyspepsia (FD) and irritable bowel syndrome (IBS). The aim of this study was to examine concurrent gastrointestinal symptoms in FD and IBS. METHODS: A total of 186 college students filled out a questionnaire regarding whether they had uninvestigated dyspepsia (UD, FD without endoscopic examination) and IBS based on Rome-II criteria. Gastrointestinal symptoms were measured using the Gastrointestinal Symptom Rating Scale (GSRS) questionnaire. RESULTS: A total of 181 students (98 males, mean age 24.6 years) completed both questionnaires. The prevalence of UD, IBS, and UD+IBS overlap was 12 (6.7%), 40 (22.1%), and 8 (4.4%), respectively. A significant UD+IBS overlap was observed (66.7% IBS in UD, 20.0% UD in IBS). Reflux scores of GSRS in either UD or IBS were significantly greater than in those without. Gastroesophageal reflux disease (GERD), defined as weekly occurring moderate symptoms of heartburn and/or acid regurgitation and evaluated using the GSRS, was found in 16 (8.8%) of the subjects. The prevalence of IBS was significantly higher in GERD patients than in non-GERD patients (50.0% vs 19.4%). CONCLUSIONS: The considerable overlap not only between UD and IBS, but also between GERD and IBS, suggests the involvement of common pathophysiological disturbances in the two conditions. Descriptors Dyspepsia, Gastroesophageal reflux, Gastrointestinal symptom rating scale, Irritable bowel syndrome, Overlap Links Book Title Database Publisher Data Source Authors Hori,K., Matsumoto,T., Miwa,H. Original/Translated Title URL Date of Electronic 20090930 PMCID PMC2852717 Editors
Survey of pathogenic free-living amoebae and Legionella spp. in mud spring recreation area	2009	Department of Earth and Environmental Sciences, National Chung Cheng University, Chiayi, Taiwan, ROC. bmhsu@ccu.edu.tw	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Water research Periodical, Abbrev. Water Res. Pub Date Free Form Jun Volume 43 Issue 11 Start Page 2817 Other Pages 2828 Notes LR: 20131121; JID: 0105072; 0 (RNA, Ribosomal, 18S); 059QF0KO0R (Water); 2008/08/11 [received]; 2009/04/01 [revised]; 2009/04/02 [accepted]; 2009/04/14 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 0043-1354; 0043-1354 Accession Number PMID: 19457534 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.watres.2009.04.002 [doi] Output Language Unknown(0) PMID 19457534 Abstract Acanthamoeba, Hartmannella, and Naegleria are free-living amoebae, ubiquitous in aquatic environments. Several species within these genera are recognized as potential human pathogens. These free-living amoebae may facilitate the proliferation of their parasitical bacteria, such as Legionella. In this study, we identified Acanthamoeba, Hartmannella, Naegleria, and Legionella using various analytical procedures and investigated their occurrence at a mud spring recreation area in Taiwan. We investigated factors potentially associated with the prevalence of the pathogens, including various water types, and physical and microbiological water quality parameters. Spring water was collected from 34 sites and Acanthamoeba, Hartmannella, Naegleria, and Legionella were detected in 8.8%, 35.3%, 14.7%, and 47.1%, respectively. The identified species of Acanthamoeba included Acanthamoeba castellanii and Acanthamoeba polyphaga. Nearly all the Hartmannella isolates are identified as Hartmannella vermiformis. The Naegleria species included Naegleria australiensis and its sister groups, and two other isolates referred to a new clade of Naegleria genotypes. The Legionella species identified included unnamed Legionella genotypes, Legionella pneumophila serotype 6, uncultured Legionella spp., Legionella lytica, Legionella drancourtii, and Legionella waltersii. Significant differences (Mann-Whitney U test, P<0.05) were observed between the presence/absence of Hartmannella and total coliforms, between the presence/absence of Naegleria and heterotrophic plate counts, and between the presence/absence of Legionella and heterotrophic plate counts. This survey confirms that pathogenic free-living amoebae and Legionella are prevalent in this Taiwanese mud spring recreation area. The presence of pathogens should be considered a potential health threat when associated with human activities in spring water. Descriptors Acanthamoeba/classification/isolation & purification, Animals, Hartmannella/classification/genetics/isolation & purification, Legionella/classification/genetics/isolation & purification, Naegleria/classification/genetics/isolation & purification, Phylogeny, RNA, Ribosomal, 18S/genetics, Recreation, Soil Microbiology, Water/parasitology, Water Microbiology Links Book Title Database Publisher Data Source Authors Hsu,B. M., Lin,C. L., Shih,F. C. Original/Translated Title URL Date of Electronic 20090414 PMCID Editors
Hybrid separation and detection device for analysis of benzene, toluene, ethylbenzene, and xylenes in complex samples	2009	Center for Bioelectronics and Biosensors, Biodesign Institute and Department of Electrical Engineering, Arizona State University, Tempe, Arizona 85287-5801, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Analytical Chemistry Periodical, Abbrev. Anal.Chem. Pub Date Free Form 1-Nov Volume 81 Issue 21 Start Page 8930 Other Pages 8935 Notes LR: 20141207; GR: U01 ES0106064-01/ES/NIEHS NIH HHS/United States; GR: U01 ES016064/ES/NIEHS NIH HHS/United States; GR: U01 ES016064-01/ES/NIEHS NIH HHS/United States; GR: U01 ES016064-02/ES/NIEHS NIH HHS/United States; GR: U01 ES016064-02S1/ES/NIEHS NIH Place of Publication United States ISSN/ISBN 1520-6882; 0003-2700 Accession Number PMID: 19780581 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; IM DOI 10.1021/ac9015769 [doi] Output Language Unknown(0) PMID 19780581 Abstract We present a hybrid system for rapid detection and analysis of benzene, toluene, ethylbenzene, and xylenes (BTEX). The system combines selective and sensitive sensing elements with a fast and miniaturized chromatographic separation method. The sensing elements are an array of microfabricated quartz crystal tuning forks modified with selective molecularly imprinted polymers, and the separation method uses optimized short columns. The high sensitivity and selectivity of the sensing elements together with the help of the separation provides fast detection and analysis of BTEX in real samples containing highly concentrated interfering agents without preconcentration or heating of columns. The low cost, low power consumption, and small size of the hybrid device are particularly suitable for occupational health, industrial safety, and epidemiological applications. Descriptors Air Pollutants/analysis/chemistry, Benzene/analysis, Benzene Derivatives/analysis, Environmental Monitoring, Gas Chromatography-Mass Spectrometry/instrumentation/methods, Molecular Imprinting/methods, Polymers/chemistry, Quartz/chemistry, Toluene/analysis, Xylenes/analysis Links Book Title Database Publisher Data Source Authors Iglesias,R. A., Tsow,F., Wang,R., Forzani,E. S., Tao,N. Original/Translated Title URL Date of Electronic PMCID PMC2782579 Editors
Temporal and spatial distribution of BTEX pollutants in the atmosphere of metropolitan areas and neighbouring towns	2009	Department of Environmental Sciences, Second University of Naples, Caserta, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Environmental monitoring and assessment Periodical, Abbrev. Environ.Monit.Assess. Pub Date Free Form Mar Volume 150 Issue 4-Jan Start Page 437 Other Pages 444 Notes LR: 20131121; JID: 8508350; 0 (Air Pollutants); 0 (Benzene Derivatives); 0 (Xylenes); 3FPU23BG52 (Toluene); J64922108F (Benzene); L5I45M5G0O (ethylbenzene); 2007/07/12 [received]; 2008/02/27 [accepted]; 2008/04/25 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1573-2959; 0167-6369 Accession Number PMID: 18437518 Language eng SubFile Journal Article; IM DOI 10.1007/s10661-008-0242-5 [doi] Output Language Unknown(0) PMID 18437518 Abstract Atmospheric BTEX [benzene, toluene, ethylbenzene, o-xylene and (m + p)-xylene] concentrations have been determined in the Naples metropolitan area (NMA) and in two suburban areas located on the north within about 25 km, during 2006. The pollutants were collected by passive samplers (24-h samplings), and analysed by GC-MS. In all the areas analysed the average atmospheric benzene concentrations were higher than the limit value fixed by the European Union for 2010 and in NMA the average concentration (9.8 microg m(-3)) also exceeded the limit fixed for 2006. High linear correlation coefficients between the average daily concentrations of the different BTEX are indicative of a single major source, most likely the vehicular traffic. The temporal and spatial distribution of BTEX relative concentrations suggest that massive emissions in NMA negatively affect the quality of the air in northern suburban areas, prevalently during the hottest months of the year, probably due to transport by local seasonal winds. The ratios between BTEX daily concentrations showed a clear dependence on the intensity of solar actinic flow, indicating a major role of photochemical processes in the air cleaning from these volatile organic pollutants. Descriptors Air Pollutants/analysis, Atmosphere, Benzene/analysis, Benzene Derivatives/analysis, Cities, Environmental Monitoring, Humans, Italy, Toluene/analysis, Urban Health, Wind, Xylenes/analysis Links Book Title Database Publisher Data Source Authors Iovino,P., Polverino,R., Salvestrini,S., Capasso,S. Original/Translated Title URL Date of Electronic 20080425 PMCID Editors
Oesophageal cancer in Golestan Province, a high-incidence area in northern Iran - a review	2009	Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, 14117 Tehran, Iran.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full European journal of cancer (Oxford, England : 1990) Periodical, Abbrev. Eur.J.Cancer Pub Date Free Form Dec Volume 45 Issue 18 Start Page 3156 Other Pages 3165 Notes LR: 20150813; GR: Intramural NIH HHS/United States; JID: 9005373; RF: 86; 2009/07/26 [received]; 2009/09/11 [revised]; 2009/09/15 [accepted]; 2009/10/01 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1879-0852; 0959-8049 Accession Number PMID: 19800783 Language eng SubFile Journal Article; Research Support, N.I.H., Intramural; Review; IM DOI 10.1016/j.ejca.2009.09.018 [doi] Output Language Unknown(0) PMID 19800783 Abstract Golestan Province, located in the south-east littoral of the Caspian Sea in northern Iran, has one of the highest rates of oesophageal cancer (OC) in the world. We review the epidemiologic studies that have investigated the epidemiologic patterns and causes of OC in this area and provide some suggestions for further studies. Oesophageal squamous cell carcinoma (OSCC) constitutes over 90% of all OC cases in Golestan. In retrospective studies, cigarettes and hookah smoking, nass use (a chewing tobacco product), opium consumption, hot tea drinking, poor oral health, low intake of fresh fruit and vegetables, and low socioeconomic status have been associated with higher risk of OSCC in Golestan. However, the association of tobacco with OSCC in this area is not as strong as that seen in Western countries. Alcohol is consumed by a very small percentage of the population and is not a risk factor for OSCC in this area. Other factors, such as polycyclic aromatic hydrocarbons, N-nitroso compounds, drinking water contaminants, infections, food contamination with mycotoxins, and genetic factors merit further investigation as risk factors for OSCC in Golestan. An ongoing cohort study in this area is an important resource for studying some of these factors and also for confirming the previously found associations. Descriptors Alcohol Drinking/adverse effects/epidemiology, Alphapapillomavirus/isolation & purification, Asia/epidemiology, Carcinoma, Squamous Cell/epidemiology/etiology, Esophageal Neoplasms/epidemiology/etiology, Female, Hot Temperature/adverse effects, Humans, Iran/epidemiology, Male, Malnutrition/complications, Opioid-Related Disorders/complications/epidemiology, Polymorphism, Genetic/genetics, Risk Factors, Smoking/adverse effects/epidemiology, Tobacco, Smokeless/adverse effects, Turkmenistan/ethnology, Water Supply Links Book Title Database Publisher Data Source Authors Islami,F., Kamangar,F., Nasrollahzadeh,D., Moller,H., Boffetta,P., Malekzadeh,R. Original/Translated Title URL Date of Electronic 20091001 PMCID Editors
Body mass index and Barrett's oesophagus in women	2009	Section of Gastroenterology, Department of Medicine, Boston University Medical Center, 88 East Concord Street, Room 7721, Boston, MA 02118, USA. brian.jacobson@bmc.org	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Gut Periodical, Abbrev. Gut Pub Date Free Form Nov Volume 58 Issue 11 Start Page 1460 Other Pages 1466 Notes LR: 20151119; GR: CA087969/CA/NCI NIH HHS/United States; GR: CA107412/CA/NCI NIH HHS/United States; GR: K07 CA107412/CA/NCI NIH HHS/United States; GR: K07 CA107412-04/CA/NCI NIH HHS/United States; GR: K08 DK070706/DK/NIDDK NIH HHS/United States; GR: K08 D Place of Publication England ISSN/ISBN 1468-3288; 0017-5749 Accession Number PMID: 19336423 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; AIM; IM DOI 10.1136/gut.2008.174508 [doi] Output Language Unknown(0) PMID 19336423 Abstract OBJECTIVE: Excess body mass is associated with symptoms of gastro-oesophageal reflux disease, and cross-sectional studies suggest an association between body mass index (BMI) and Barrett's oesophagus. The present study sought prospectively to examine the influence of BMI and other anthropomorphic measures on the risk for Barrett's oesophagus among women. METHODS: This was a prospective study of 15 861 women who participated in the Nurses' Health Study, without a history of cancer, who underwent upper gastrointestinal endoscopy for any reason between 1986 and 2004. The main outcome measures were 261 cases of pathologically confirmed specialised intestinal metaplasia within the oesophagus (Barrett's oesophagus). Self-reported data on weight were collected from biennial questionnaires. Self-reported height was collected in 1976, and self-reported waist and hip circumferences were collected in 1986. RESULTS: Compared with women with a BMI of 20-24.9 kg/m(2), women with a BMI of 25-29.9 had a multivariate OR for Barrett's oesophagus of 0.92 (95% CI 0.66 to 1.27), women with a BMI > or =30 had a multivariate OR of 1.52 (95% CI 1.02 to 2.28) and women with a BMI <20 had a multivariate OR of 0.92 (95% CI 0.65 to 1.31). Results were similar when controlling for symptoms of gastro-oesophageal reflux, and among the entire Nurses' Health Study cohort (n = 93 609) regardless of a history of endoscopy. In contrast, waist-to-hip ratio, waist circumference and height did not appear to be associated with Barrett's oesophagus. CONCLUSIONS: Obese, but not overweight, women appear to be at increased risk for Barrett's oesophagus. Descriptors Adult, Barrett Esophagus/etiology, Body Mass Index, Endoscopy, Digestive System, Female, Gastroesophageal Reflux/complications, Humans, Intestines/pathology, Metaplasia/pathology, Middle Aged, Odds Ratio, Overweight/complications, Precancerous Conditions/etiology, Prospective Studies, Risk Factors, Surveys and Questionnaires, Waist Circumference, Waist-Hip Ratio Links Book Title Database Publisher Data Source Authors Jacobson,B. C., Chan,A. T., Giovannucci,E. L., Fuchs,C. S. Original/Translated Title URL Date of Electronic 20090330 PMCID PMC2763036 Editors

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