WTS database

Title	Pub Year Sort ascending	SearchLink
Assessment of DNA damage using chromosomal aberrations assay in lymphocytes of waterpipe smokers	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Int J Occup Med Environ Health Periodical, Abbrev. Int.J.Occup.Med.Environ.Health Pub Date Free Form Volume 25 Issue 3 Start Page 218 Other Pages 24 Notes ID: 22729491 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract OBJECTIVES: The aim of this study was to investigate the genotoxicity of waterpipe smoking in the lymphocytes of waterpipe smokers using chromosomal aberrations (CAs) assay. MATERIALS AND METHODS: Fifty waterpipe smokers and 18 healthy non-smokers volunteered to participate in the study. Additionally, 18 heavy cigarette smokers were recruited for comparison. Chromosomal aberrations (CAs) assay was used to evaluate DNA damage in the lymphocytes. RESULTS: The results showed that similarly to cigarette smoking, waterpipe smoking significantly increased the frequencies of CAs (p Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Alsatari,Enas S., Azab,Mohammad, Khabour,Omar F., Alzoubi,Karem H., Sadiq,May F. Original/Translated Title URL Date of Electronic PMCID Editors
Tobacco smoking using Midwakh is an emerging health problem--evidence from a large cross-sectional survey in the United Arab Emirates	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PLoS One Periodical, Abbrev. Pub Date Free Form Volume 7 Issue 6 Start Page e39189 Other Pages e39189 Notes ID: 22720071 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract INTRODUCTION: Accurate information about the prevalence and types of tobacco use is essential to deliver effective public health policy. We aimed to study the prevalence and modes of tobacco consumption in the United Arab Emirates (UAE), particularly focusing on the use of Midwakh (Arabic traditional pipe). METHODS: We studied 170,430 UAE nationals aged â‰¥ 18 years (44% males and 56% females) in the Weqaya population-based screening program in Abu Dhabi residents during the period April 2008-June 2010. Self-reported smoking status, type, quantity and duration of tobacco smoked were recorded. Descriptive statistics were used to describe the study findings; prevalence rates used the screened sample as the denominator. RESULT: The prevalence of smoking overall was 24.3% in males and 0.8% in females and highest in males aged 20-39. Mean age (SD) of smokers was 32.8 (11.1) years, 32.7 (11.1) in males and 35.7 (12.1) in females. Cigarette smoking was the commonest form of tobacco use (77.4% of smokers), followed by Midwakh (15.0%), shisha (waterpipe) (6.8%), and cigar (0.66%). The mean durations of smoking for cigarettes, Midwakh, shisha and cigars were 11.4, 9.3, 7.6 and 11.0 years, respectively. CONCLUSIONS: Smoking is most common among younger UAE national men. The use of Midwakh and the relatively young age of onset of Midwakh smokers is of particular concern as is the possibility of the habit spreading to other countries. Comprehensive tobacco control laws targeting the young and the use of Midwakh are needed. Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Al-Houqani, Mohammed, Ali,Raghib, Hajat,Cother Original/Translated Title URL Date of Electronic PMCID Editors
Attitudes of Cairo University medical students toward smoking: the need for tobacco control programs in medical education	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full J Egypt Public Health Assoc Periodical, Abbrev. J.Egypt.Public Health Assoc. Pub Date Free Form Volume 87 Issue 2-Jan Start Page 1 Other Pages 7 Notes ID: 22415329 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract BACKGROUND: Tobacco smoking rates are increasing in developing countries and so are tobacco-related chronic diseases. Reported figures from the WHO show rates of smoking in Egypt as high as 20% but limited information is available about smoking specifically among physicians and medical students. MATERIALS AND METHODS: Final-year medical students of Cairo University were surveyed regarding their tobacco behavior and attitudes using a modified Global Health Professions Student Survey. We approached 220 students by randomly selecting clinical units into which they were assigned and requested completion of the survey. RESULTS: Ever users of some form of tobacco comprised 46.7% of students sampled, current users of cigarettes comprised 17.4%, and current users of water pipe 'sheesha' comprised 17.6%. The vast majority (87.7%) of students believed that smoking is a public health problem in Cairo and supported restriction of tobacco. Yet, only 58.5% stated that they were taught it is important for physicians to provide tobacco education materials to patients. Among ever users of cigarettes, 54.4% believed health professionals do not serve as health role models for patients, and only a small percentage of all students (34.2%) stated that they had received some form of training on smoking cessation in their medical curriculum to be able to instruct patients. CONCLUSION AND RECOMMENDATIONS: A high rate of smoking was revealed among medical students in Cairo. Overall, approximately 23.4% of students were currently smoking cigarettes and/or sheesha, and 46.7% were ever users of some form of tobacco. A formal antitobacco program for medical students should be incorporated into their medical curriculum to change the attitudes of medical students and overcome the anticipated increase in chronic diseases in Egypt. Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Khan,Adeel A.M., Dey,Subhojit, Taha,Alaa H., Huq,Farhan S., Moussawi,Ahmad H., Omar,Omar S., Soliman,Amr S. Original/Translated Title URL Date of Electronic PMCID Editors
Water-pipe smoking and metabolic syndrome: a population-based study	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PLoS One Periodical, Abbrev. Pub Date Free Form Volume 7 Issue 7 Start Page e39734 Other Pages e39734 Notes ID: 22848361 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract Water-pipe (WP) smoking has significantly increased in the last decade worldwide. Compelling evidence suggests that the toxicants in WP smoke are similar to that of cigarette smoke. The WP smoking in a single session could have acute harmful health effects even worse than cigarette smoking. However, there is no evidence as such on long term WP smoking and its impact on chronic health conditions particularly cardiovascular and metabolic conditions. Therefore, we conducted this study to investigate the relationship between WP smoking and metabolic syndrome (MetS). This was a cross-sectional study carried out in Punjab province of Pakistan using the baseline data of a population-based study--Urban Rural Chronic Diseases Study (URCDS). Information was collected by trained nurses regarding the socio-demographic profile, lifestyle factors including WP smoking, current and past illnesses. A blood sample was obtained for measurement of complete blood count, lipid profile and fasting glucose level. MetS was ascertained by using the International Diabetic Federation's criteria. We carried out multiple logistic regressions to investigate the association between WP smoking and MetS. Final sample included 2,032 individuals--of those 325 (16.0%) were current WP smokers. Age adjusted-prevalence of MetS was significantly higher among current WP smokers (33.1%) compared with non-smokers (14.8%). Water-pipe smokers were three times more likely to have MetS (OR 3.21, 95% CI 2.38-4.33) compared with non-smokers after adjustment for age, sex and social class. WP smokers were significantly more likely to have hypertriglyceridemia (OR 1.63, 95% CI 1.25-2.10), hyperglycaemia (OR 1.82, 95% CI 1.37-2.41), Hypertension (OR 1.95, 95% CI 1.51-2.51) and abdominal obesity (OR 1.93, 95% CI 1.52-2.45). However, there were no significant differences in HDL level between WP smokers and non-smokers. This study suggests that WP smoking has a significant positive (harmful) relationship with MetS and its components. Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Shafique,Kashif, Mirza,Saira Saeed, Mughal,Muhammad Kashif, Arain,Zain Islam, Khan,Naveed Ahmed, Tareen,Muhammad Farooq, Ahmad,Ishtiaque Original/Translated Title URL Date of Electronic PMCID Editors
Is opium a real risk factor for esophageal cancer or just a methodological artifact? Hospital and neighborhood controls in case-control studies	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PLoS One Periodical, Abbrev. Pub Date Free Form Volume 7 Issue 3 Start Page e32711 Other Pages e32711 Notes ID: 22396792 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract BACKGROUND: Control selection is a major challenge in epidemiologic case-control studies. The aim of our study was to evaluate using hospital versus neighborhood control groups in studying risk factors of esophageal squamous cell carcinoma (ESCC). METHODOLOGY/PRINCIPAL FINDINGS: We compared the results of two different case-control studies of ESCC conducted in the same region by a single research group. Case definition and enrollment were the same in the two studies, but control selection differed. In the first study, we selected two age- and sex-matched controls from inpatient subjects in hospitals, while for the second we selected two age- and sex-matched controls from each subject's neighborhood of residence. We used the test of heterogeneity to compare the results of the two studies. We found no significant differences in exposure data for tobacco-related variables such as cigarette smoking, chewing Nass (a tobacco product) and hookah (water pipe) usage, but the frequency of opium usage was significantly different between hospital and neighborhood controls. Consequently, the inference drawn for the association between ESCC and tobacco use did not differ between the studies, but it did for opium use. In the study using neighborhood controls, opium use was associated with a significantly increased risk of ESCC (adjusted OR 1.77, 95% CI 1.17-2.68), while in the study using hospital controls, this was not the case (OR 1.09, 95% CI 0.63-1.87). Comparing the prevalence of opium consumption in the two control groups and a cohort enrolled from the same geographic area suggested that the neighborhood controls were more representative of the study base population for this exposure. CONCLUSIONS/SIGNIFICANCE: Hospital and neighborhood controls did not lead us to the same conclusion for a major hypothesized risk factor for ESCC in this population. Our results show that control group selection is critical in drawing appropriate conclusions in observational studies. Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Shakeri,Ramin, Kamangar,Farin, Nasrollahzadeh,Dariush, Nouraie,Mehdi, Khademi,Hooman, Etemadi,Arash, Islami,Farhad, Marjani,Hajiamin, Fahimi,Saman, Sepehr,Alireza, Rahmati,Atieh, Abnet,Christian C., Dawsey,Sanford M., Brennan,Paul, Boffetta,Paolo, Malekzadeh,Reza, Majdzadeh,Reza Original/Translated Title URL Date of Electronic PMCID Editors
In vitro cytotoxicity and mutagenicity of mainstream waterpipe smoke and its functional consequences on alveolar type II derived cells	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Toxicol Lett Periodical, Abbrev. Toxicol.Lett. Pub Date Free Form Volume 211 Issue 3 Start Page 220 Other Pages 31 Notes ID: 22516759 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract INTRODUCTION: While waterpipe tobacco smoking has become a global phenomenon, its potential health consequences are poorly understood. In this manuscript, we report the in vitro mutagenicity of waterpipe smoke condensate (WSC), the alteration in cellular parameters of lung alveolar cells in response to WSC exposure and discuss the implication of cellular responses in the pathophysiology of chronic obstructive pulmonary disease (COPD). METHODS: The mainstream WSC was generated using a standard laboratory machine protocol. We assessed its mutagenicity using Ames test. In addition, we studied the effect of WSC on the proliferation and cell cycle of alveolar type II cells and vascular endothelial cells. We also assessed the effect of WSC on the expression of genes involved in cell cycle arrest and inflammation. RESULTS: Within the range of tested doses, WSC did not elicit sufficient response to be considered mutagenic in any of the strains tested (TA98, TA100, TA102, and TA97a) but were found to be toxic for strains TA97a and TA102 at the highest tested doses. However, WSC induced cell cycle arrest and cellular senescence mediated by the p53-p21 pathway. Also our study indicated that WSC induced an increase in the transcriptional expression of matrix metalloproteinases, MMP-2 and MMP-9 and an immune response regulator, Toll Like Receptor-4. CONCLUSION: The data reported here represent the first in vitro demonstration of the effect of waterpipe smoke on cellular parameters providing evidence of the potential involvement of WPS in the pathogenesis of COPD through impairing cellular growth and inducing inflammation. Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Rammah,Mayyasa, Dandachi,Farah, Salman,Rola, Shihadeh,Alan, El-Sabban, Marwan Original/Translated Title URL Date of Electronic PMCID Editors
Happy hookah hour	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Curr Opin Pulm Med Periodical, Abbrev. Curr.Opin.Pulm.Med. Pub Date Free Form Volume 18 Issue 2 Start Page 95 Other Pages 6 Notes ID: 22234276 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors Links http://dx.doi.org/10.1097/MCP.0b013e328350266d Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Varkey,Basil Original/Translated Title URL Date of Electronic PMCID Editors
Waterpipe smoking: a new tobacco pandemic entailing severe health risks?	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Arch Toxicol Periodical, Abbrev. Arch.Toxicol. Pub Date Free Form Volume 86 Issue 8 Start Page 1161 Other Pages 2 Notes ID: 22684767 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors Links http://dx.doi.org/10.1007/s00204-012-0885-4 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Luch,Andreas Original/Translated Title URL Date of Electronic PMCID Editors
Keeping the night going: the role of hookah bars in evening drinking behaviours	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Public health Periodical, Abbrev. Public Health Pub Date Free Form Volume 126 Issue 12 Start Page 1078 Other Pages 81 Notes ID: 22819668 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors Links http://dx.doi.org/10.1016/j.puhe.2012.06.010 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Soule,E K., Barnett,T E., Curbow,B A. Original/Translated Title URL Date of Electronic PMCID Editors
Prevention and sporadic carbon monoxide poisoning related to shisha (hookah, narghile) tobacco smoking	2012	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full J Emerg Med Periodical, Abbrev. J.Emerg.Med. Pub Date Free Form Volume 42 Issue 1 Start Page 65 Other Pages 6 Notes ID: 20133102 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors Links http://dx.doi.org/10.1016/j.jemermed.2009.11.027 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Chaouachi,Kamal Original/Translated Title URL Date of Electronic PMCID Editors

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