Skip to main content
Title Pub Year Sort ascending Author SearchLink
Microbial, saccharifying and antioxidant properties of an Indian rice based fermented beverage 2015 Department of Microbiology, Vidyasagar University, Midnapore 721102, West Bengal, India.; Department of Microbiology, Vidyasagar University, Midnapore 721102, West Bengal, India.; Department of Microbiology, Vidyasagar University, Midnapore 721102, West B
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Food Chemistry
Periodical, Abbrev.
Food Chem.
Pub Date Free Form
1-Feb
Volume
168
Issue
Start Page
196
Other Pages
202
Notes
CI: Copyright (c) 2014; JID: 7702639; 0 (Antioxidants); OTO: NOTNLM; 2014/04/12 [received]; 2014/06/26 [revised]; 2014/07/07 [accepted]; 2014/07/16 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
0308-8146; 0308-8146
Accession Number
PMID: 25172700
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.foodchem.2014.07.042 [doi]
Output Language
Unknown(0)
PMID
25172700
Abstract
Haria, a popular rice based ethnic fermented beverage, is consumed as a staple food and refreshing drink by the vast number of Indian tribal people. In this study, the composition of microbial consortia and the occurrence of some important nutraceuticals during haria preparation were investigated. The quantities of moulds and yeasts were highest at 2nd day, and then declined, but, on the contrary, the quantity of Lactic Acid Bacteria and Bifidobacterium sp. increased concurrently during the course of fermentation. Accumulation of starch hydrolytic enzymes along with different types of malto-oligosaccharides like maltotetrose (26.18mug/gm), maltotriose (28.16mug/gm), and maltose (26.94mug/gm) were also noted. Furthermore, GC-MS analysis indicated the occurrence of pyranose derivatives in the fermented products. The fermented materials showed higher free radicals scavenging activity (82.54%, 4th day) against DPPH radicals. These studies clearly demonstrated that the microbial interaction during fermentation of rice makes it more nutritious, and most likely more beneficial for health.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Ghosh,K., Ray,M., Adak,A., Dey,P., Halder,S.K., Das,A., Jana,A., Parua Mondal,S., Das Mohapatra,P.K., Pati,B.R., Mondal,K.C.
Original/Translated Title
URL
Date of Electronic
20140716
PMCID
Editors
Contraceptive service needs of women with young children presenting for pediatric care 2015 Department of Pediatrics, Johns Hopkins University School of Medicine, 200 N. Wolfe Street, Baltimore, MD 21287, USA; Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Contraception
Periodical, Abbrev.
Contraception
Pub Date Free Form
Nov
Volume
92
Issue
5
Start Page
508
Other Pages
512
Notes
LR: 20160326; CI: Copyright (c) 2015; GR: P20 MD000198/MD/NIMHD NIH HHS/United States; GR: P20 MD000198/MD/NIMHD NIH HHS/United States; JID: 0234361; NIHMS715366; OID: NLM: NIHMS715366 [Available on 11/01/16]; OID: NLM: PMC4807654 [Available on 11/01/16];
Place of Publication
United States
ISSN/ISBN
1879-0518; 0010-7824
Accession Number
PMID: 26197265
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.contraception.2015.07.004 [doi]
Output Language
Unknown(0)
PMID
26197265
Abstract
OBJECTIVES: The primary objective of this study is to characterize the need for contraceptive services and contraceptive method use among women with young children presenting to child health clinics. A secondary objective is to characterize the factors, including access to care and health needs, that exist in this population and to evaluate their association with contraceptive method use. STUDY DESIGN: This is a cross-sectional study of women with children under age 36 months presenting to four child health practices in the Baltimore, Maryland, area. Participating women completed a survey to assess desire for pregnancy, contraceptive method use and related characteristics. RESULTS: A total of 238 participants (82%) were in need of contraceptive services (fertile and not desiring pregnancy). Overall, 59 (25%) of women in need were not using a contraceptive method (unmet need) and 79 (33%) were using a highly effective method (implant or intrauterine device). Factors associated with lower odds of unmet need for contraceptive services included attendance at a routine postpartum visit and visiting a healthcare provider to discuss contraception after pregnancy. Approximately half of index pregnancies were unintended and this was the only health factor associated with greater odds of using of a highly effective contraceptive method. CONCLUSIONS: Most women presenting with young children for pediatric care indicated that they were not currently trying to become pregnant and reported current methods of pregnancy prevention that ranged from none to highly effective. Women who had not sought postpregnancy contraceptive care were more likely to have unmet need for contraceptive services. IMPLICATIONS: Child health clinics may be a novel site for providing contraceptive care to women with children as part of a strategy to reduce unplanned pregnancies.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Upadhya,K.K., Burke,A.E., Marcell,A.V., Mistry,K., Cheng,T.L.
Original/Translated Title
URL
Date of Electronic
20150718
PMCID
PMC4807654
Editors
Leaching of lead from new unplasticized polyvinyl chloride (uPVC) pipes into drinking water 2015 Department of Civil and Environmental Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117576, Singapore.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science and pollution research international
Periodical, Abbrev.
Environ.Sci.Pollut.Res.Int.
Pub Date Free Form
Jun
Volume
22
Issue
11
Start Page
8405
Other Pages
8411
Notes
JID: 9441769; 0 (Chelating Agents); 0 (Chloramines); 0 (Disinfectants); 0 (Drinking Water); 0 (Water Pollutants, Chemical); 10599-90-3 (chloramine); 2P299V784P (Lead); 4R7X1O2820 (Chlorine); 9002-86-2 (Polyvinyl Chloride); 9G34HU7RV0 (Edetic Acid); 2014/1
Place of Publication
Germany
ISSN/ISBN
1614-7499; 0944-1344
Accession Number
PMID: 25539706
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s11356-014-3999-9 [doi]
Output Language
Unknown(0)
PMID
25539706
Abstract
Unplasticized polyvinyl chloride (uPVC) pipes have been used in the premise plumbing system due to their high strength, long-term durability, and low cost. uPVC pipes, however, may contain lead due to the use of lead compounds as the stabilizer during the manufacturing process. The release of lead from three locally purchased uPVC pipes was investigated in this study. The effects of various water quality parameters including pH value, temperature, and type of disinfectant on the rate of lead release were examined. The elemental mapping obtained using scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX) confirmed the presence of lead on the inner surfaces of the uPVC pipes and their surface lead weight percentages were determined. The leachable lead concentration for each pipe was determined using high strength acidic EDTA solutions (pH 4, EDTA = 100 mg/L). Lead leaching experiments using tap water and reconstituted tape water under static conditions showed that the rate of lead release increased with the decreasing pH value and increasing temperature. In the presence of monochloramine, lead release was faster than that in the presence of free chlorine.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Zhang,Y., Lin,Y.P.
Original/Translated Title
URL
Date of Electronic
20141225
PMCID
Editors
Smoke-free air laws and quit attempts: Evidence for a moderating role of spontaneous self-affirmation 2015 Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Cancer Institute, USA. Electronic address: persoskie@gmail.com.; Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Canc
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Social science & medicine (1982)
Periodical, Abbrev.
Soc.Sci.Med.
Pub Date Free Form
Sep
Volume
141
Issue
Start Page
46
Other Pages
55
Notes
CI: Published by Elsevier Ltd.; JID: 8303205; 0 (Tobacco Smoke Pollution); OTO: NOTNLM; 2014/10/27 [received]; 2015/07/15 [revised]; 2015/07/17 [accepted]; 2015/07/20 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1873-5347; 0277-9536
Accession Number
PMID: 26246033
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.socscimed.2015.07.015 [doi]
Output Language
Unknown(0)
PMID
26246033
Abstract
BACKGROUND: In addition to their primary goal of protecting nonsmokers from secondhand smoke, smoke-free air laws may also encourage intentions to quit smoking, quit attempts, and cessation among smokers. However, laws may not encourage quitting if smokers feel threatened by them and react defensively. OBJECTIVE: This study examined whether spontaneous self-affirmation - the extent to which people think about their values or strengths when they feel threatened - may reduce smokers' reactance to smoke-free laws, enhancing the ability of the laws to encourage quitting. METHOD: We linked state-level information on the comprehensiveness of U.S. smoke-free laws (compiled in January, 2013 by the American Lung Association) with data from a U.S. health survey (Health Information National Trends Survey) collected from September-December, 2013 (N = 345 current smokers; 587 former smokers). RESULTS: Smoke-free laws interacted with self-affirmation to predict quit attempts in the past year and intentions to quit in the next six months: Smokers higher in self-affirmation reported more quit attempts and quit intentions if they lived in states with more comprehensive smoke-free laws. There was some evidence of a "boomerang" effect (i.e., less likelihood of making a quit attempt) among smokers low in self-affirmation if living in states with more comprehensive smoke-free laws, but this effect was significant only among smokers extremely low in self-affirmation. For quit intentions, there was no evidence for a boomerang effect of smoke-free laws even among smokers extremely low in self-affirmation. More comprehensive smoke-free laws were not associated with smoking status (former vs. current smoker) or average amount smoked per day, nor did they interact with self-affirmation to predict these outcomes. CONCLUSIONS: The impact of smoke-free policies on quit attempts and quit intentions may be moderated by psychological characteristics such as the tendency to spontaneously self-affirm. Follow-ups should experimentally manipulate self-affirmation and examine effects of smoke-free laws in controlled contexts.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Persoskie,A., Ferrer,R.A., Taber,J.M., Klein,W.M., Parascandola,M., Harris,P.R.
Original/Translated Title
URL
Date of Electronic
20150720
PMCID
Editors
Comparative Effectiveness of Post-Discharge Strategies for Hospitalized Smokers: study protocol for the Helping HAND 2 randomized controlled trial 2015 Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, USA. zreid@partners.org.; Mongan Institute for Health Policy, Massachusetts General Hospital and Partners HealthCare, Boston, MA, USA. zreid@partners.org.; Tobacco Research
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
7-Feb
Volume
15
Issue
Start Page
109
Other Pages
015-1484-0
Notes
LR: 20151111; ClinicalTrials.gov/NCT01714323; GR: 1R01HL111821-01/HL/NHLBI NIH HHS/United States; GR: 3R01HL111821-01S1/HL/NHLBI NIH HHS/United States; GR: R01 HL111821/HL/NHLBI NIH HHS/United States; JID: 100968562; OID: NLM: PMC4328622; 2015/01/21 [rece
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 25879193
Language
eng
SubFile
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM
DOI
10.1186/s12889-015-1484-0 [doi]
Output Language
Unknown(0)
PMID
25879193
Abstract
BACKGROUND: Smoking cessation interventions for hospitalized smokers are effective in promoting smoking cessation, but only if the tobacco dependence treatment continues after the patient leaves the hospital. Sustaining tobacco dependence treatment after hospital discharge is a challenge for health care systems. Our previous single-site randomized controlled trial demonstrated the effectiveness of an intervention that facilitated the delivery of comprehensive tobacco cessation treatment, including both medication and counseling, after hospital discharge. We subsequently streamlined the intervention model to increase its potential for dissemination. This new model is being tested in a larger multi-site trial with broader eligibility criteria in order to enroll a more representative sample of hospitalized smokers. This paper describes the trial design and contrasts it with the earlier study. METHODS/DESIGN: A 2-arm, 3-site randomized controlled trial is testing the hypothesis that a multi-component Sustained Care intervention is more effective than Standard Care in helping hospitalized cigarette smokers stop smoking after hospital discharge. The trial enrolls adult daily cigarette smokers who are admitted to 1 of 3 participating hospitals in Massachusetts or Pennsylvania. Participants receive the same smoking cessation intervention in the hospital. They are randomly assigned to receive either Standard Care or Sustained Care after hospital discharge. Participants in the Sustained Care arm receive a free 3-month supply of FDA-approved smoking cessation medication and 5 interactive voice response calls that provide tailored motivational messages, medication refills, and access to a live tobacco treatment counselor. Participants in the Standard Care arm receive a smoking cessation medication recommendation and information about community resources. Outcomes are assessed at 1, 3, and 6 months after discharge. The primary outcome is biochemically-validated tobacco abstinence for the past 7 days at 6-month follow-up. Other outcome measures include self-reported tobacco abstinence measures, use of medication and counseling after discharge, hospital readmissions, and program cost-effectiveness. DISCUSSION: We adapted a proven intervention for hospitalized smokers to enhance its potential for dissemination and are testing it in a multi-site trial. Study enrollment data suggests that the trial achieved the goal of recruiting a broader sample of hospitalized smokers. TRIAL REGISTRATION: Comparative Effectiveness of Post-Discharge Strategies for Hospitalized Smokers (Helping HAND2) NCT01714323. Registered October 22, 2012.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Reid,Z.Z., Regan,S., Kelley,J.H., Streck,J.M., Ylioja,T., Tindle,H.A., Chang,Y., Levy,D.E., Park,E.R., Singer,D.E., Carpenter,K.M., Reyen,M., Rigotti,N.A.
Original/Translated Title
URL
Date of Electronic
20150207
PMCID
PMC4328622
Editors
E-cigarette use in the past and quitting behavior in the future: a population-based study 2015 Wael K. Al-Delaimy, Eric C. Leas, and David R. Strong are with the Department of Family Medicine and Public Health, University of California, San Diego. Mark G. Myers is with the Psychology Service, Veterans Affairs San Diego Healthcare System, and the De
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Public Health
Periodical, Abbrev.
Am.J.Public Health
Pub Date Free Form
Jun
Volume
105
Issue
6
Start Page
1213
Other Pages
1219
Notes
LR: 20160105; JID: 1254074; CIN: Am J Public Health. 2015 Nov;105(11):e1. PMID: 26270297; CIN: Am J Public Health. 2015 Nov;105(11):e1-2. PMID: 26378864; EIN: Am J Public Health. 2015 Sep;105(9):e7. PMID: 26252076; 2015/04/16 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1541-0048; 0090-0036
Accession Number
PMID: 25880947
Language
eng
SubFile
Journal Article; AIM; IM
DOI
10.2105/AJPH.2014.302482 [doi]
Output Language
Unknown(0)
PMID
25880947
Abstract
OBJECTIVES: We examined whether smokers who used e-cigarettes are more likely to quit after 1 year than smokers who had never used e-cigarettes. METHODS: We surveyed California smokers (n = 1000) at 2 time points 1 year apart. We conducted logistic regression analyses to determine whether history of e-cigarette use at baseline predicted quitting behavior at follow-up, adjusting for demographics and smoking behavior at baseline. We limited analyses to smokers who reported consistent e-cigarette behavior at baseline and follow-up. RESULTS: Compared with smokers who never used e-cigarettes, smokers who ever used e-cigarettes were significantly less likely to decrease cigarette consumption (odds ratio [OR] = 0.51; 95% confidence interval [CI] = 0.30, 0.87), and significantly less likely to quit for 30 days or more at follow-up (OR = 0.41; 95% CI = 0.18, 0.93). Ever-users of e-cigarettes were more likely to report a quit attempt, although this was not statistically significant (OR = 1.15; 95% CI = 0.67, 1.97). CONCLUSIONS: Smokers who have used e-cigarettes may be at increased risk for not being able to quit smoking. These findings, which need to be confirmed by longer-term cohort studies, have important policy and regulation implications regarding the use of e-cigarettes among smokers.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Al-Delaimy,W.K., Myers,M.G., Leas,E.C., Strong,D.R., Hofstetter,C.R.
Original/Translated Title
URL
Date of Electronic
20150416
PMCID
Editors
Effect of plasmids harbouring blaCTX-M on the virulence and fitness of Escherichia coli ST131 isolates 2015 Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 440-746, South Korea.; Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University Scho
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of antimicrobial agents
Periodical, Abbrev.
Int.J.Antimicrob.Agents
Pub Date Free Form
Aug
Volume
46
Issue
2
Start Page
214
Other Pages
218
Notes
CI: Copyright (c) 2015; JID: 9111860; EC 3.5.2.- (beta-lactamase CTX-M-14); EC 3.5.2.- (beta-lactamase CTX-M-15); EC 3.5.2.6 (beta-Lactamases); OTO: NOTNLM; 2014/11/27 [received]; 2015/04/23 [revised]; 2015/04/26 [accepted]; 2015/06/04 [aheadofprint]; ppu
Place of Publication
Netherlands
ISSN/ISBN
1872-7913; 0924-8579
Accession Number
PMID: 26116415
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.ijantimicag.2015.04.012 [doi]
Output Language
Unknown(0)
PMID
26116415
Abstract
The effect of plasmids harbouring blaCTX-M on the virulence and fitness on Escherichia coli sequence type 131 (ST131) isolates was investigated. Plasmids harbouring blaCTX-M-14 or blaCTX-M-15 were transferred by transconjugation into five non-extended-spectrum beta-lactamase (ESBL)-producing ST131 isolates. Clinical non-ESBL-producing ST131 isolates demonstrated a higher degree of biofilm formation and serum resistance compared with CTX-M-producing ST131 isolates. In addition, non-ESBL-producing isolates were more competitive than CTX-M-producing isolates. Transconjugants showed no significant defect in growth rate and competitiveness compared with their hosts. However, serum resistance and biofilm formation were diminished in the transconjugants. In conclusion, non-ESBL-producing E. coli ST131 isolates were more competitive and virulent than CTX-M-producing E. coli ST131 isolates. However, transconjugants harbouring blaCTX-M were no less competitive than their susceptible hosts, which may partially explain the global dissemination of CTX-M-14- and CTX-M-15-producing E. coli ST131 isolates, in addition to their increased antimicrobial resistance.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V. and the International Society of Chemotherapy
Data Source
Authors
Shin,J., Ko,K.S.
Original/Translated Title
URL
Date of Electronic
20150604
PMCID
Editors
The effects of nicotine stimulus and response expectancies on male and female smokers' responses to nicotine-free electronic cigarettes 2015 Department of Psychology and Neuroscience, Dalhousie University, Canada.; Department of Psychology and Neuroscience, Dalhousie University, Canada.; School of Psychological Sciences, Tel Aviv University, Israel.; Department of Psychology and Neuroscience,
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
Jan
Volume
40
Issue
Start Page
144
Other Pages
147
Notes
LR: 20151119; CI: Copyright (c) 2014; JID: 7603486; 0 (Nicotinic Agonists); 6M3C89ZY6R (Nicotine); OTO: NOTNLM; 2014/07/09 [received]; 2014/09/07 [revised]; 2014/09/10 [accepted]; 2014/09/18 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1873-6327; 0306-4603
Accession Number
PMID: 25261789
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.addbeh.2014.09.013 [doi]
Output Language
Unknown(0)
PMID
25261789
Abstract
BACKGROUND: Electronic cigarettes (e-cigarettes) have been reported to reduce tobacco craving and withdrawal; however, the mechanisms underlying these effects have not been elucidated. METHODS: This study examined the contributions of nicotine stimulus and response expectancies to responses to nicotine-free e-cigarettes in 21 e-cigarette naive smokers (12 male). Participants completed two randomized experimental sessions in which they administered a nicotine-free e-cigarette. During one session they were informed that the e-cigarette contained nicotine and during the other session they were informed that the e-cigarette was nicotine-free. Participants completed subjective assessments before and immediately after sampling ten puffs from the e-cigarette and were then invited to earn additional puffs using a computerized progressive ratio task. Prior to their enrolment in the study, participants provided an estimate of the relative importance of the nicotine content of e-cigarettes for craving relief. RESULTS: Instructions that the e-cigarette contained nicotine were found to reduce both intention to smoke (p=0.017) and withdrawal-related (p=0.018) craving, regardless of a-priori reported beliefs regarding the relative importance of nicotine. Nicotine content instructions were also found to be associated with a shorter latency to self-administration (p=0.005); however, a SexxInstructionsxResponse Expectancy interaction (p=0.008) revealed that this effect was specific to women who had strong a-priori nicotine content craving relief expectations. Neither nicotine content instructions nor response expectancies impacted the number of puffs self-administered. CONCLUSIONS: Findings suggest that nicotine content expectations contribute to smokers' responses to e-cigarettes, and that a-priori beliefs about nicotine effects may be especially important in women.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Copp,S.R., Collins,J.L., Dar,R., Barrett,S.P.
Original/Translated Title
URL
Date of Electronic
20140918
PMCID
Editors
Increasing prevalence of electronic cigarette use among smokers hospitalized in 5 US cities, 2010-2013 2015 Tobacco Research and Treatment Center, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA; nrigotti@partners.org.; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham,
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
17
Issue
2
Start Page
236
Other Pages
244
Notes
LR: 20160519; CI: (c) The Author 2014; GR: R01 HL111821/HL/NHLBI NIH HHS/United States; GR: R01HL111821/HL/NHLBI NIH HHS/United States; GR: RC1 HL099668/HL/NHLBI NIH HHS/United States; GR: RC1HL099668/HL/NHLBI NIH HHS/United States; GR: U01 DA031515/DA/NI
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25168031
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1093/ntr/ntu138 [doi]
Output Language
Unknown(0)
PMID
25168031
Abstract
INTRODUCTION: Little is known about the pattern of electronic cigarette (e-cigarette) use over time or among smokers with medical comorbidity. METHODS: We assessed current cigarette smokers' use of e-cigarettes during the 30 days before admission to 9 hospitals in 5 geographically dispersed US cities: Birmingham, AL; Boston, MA; Kansas City, KS; New York, NY; and Portland, OR. Each hospital was conducting a randomized controlled trial as part of the NIH-sponsored Consortium of Hospitals Advancing Research on Tobacco (CHART). We conducted a pooled analysis using multiple logistic regression to examine changes in e-cigarette use over time and to identify correlates of e-cigarette use. RESULTS: Among 4,660 smokers hospitalized between July 2010 and December 2013 (mean age 57 years, 57% male, 71% white, 56% some college, average 14 cigarettes/day), 14% reported using an e-cigarette during the 30 days before admission. The prevalence of e-cigarette use increased from 1.1% in 2010 to 10.3% in 2011, 10.2% in 2012, and 18.4% in 2013; the increase was statistically significant (p
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Rigotti,N.A., Harrington,K.F., Richter,K., Fellows,J.L., Sherman,S.E., Grossman,E., Chang,Y., Tindle,H.A., Ylioja,T., Consortium of Hospitals Advancing Research on Tobacco
Original/Translated Title
URL
Date of Electronic
20140828
PMCID
PMC4837996
Editors
Contact allergy induced by bisphenol A diglycidyl ether leachables from aluminium tubes for pharmaceutical use 2015 Department of Allergology and Occupational Dermatology, Dermatologikum Hamburg, Hamburg, Germany.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Allergy
Periodical, Abbrev.
Allergy
Pub Date Free Form
Feb
Volume
70
Issue
2
Start Page
220
Other Pages
226
Notes
CI: (c) 2014; JID: 7804028; 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (Ointments); CPD4NFA903 (Aluminum); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); OTO: NOTNLM; 2014/10/23 [accepted]; ppublish
Place of Publication
Denmark
ISSN/ISBN
1398-9995; 0105-4538
Accession Number
PMID: 25582652
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1111/all.12538 [doi]
Output Language
Unknown(0)
PMID
25582652
Abstract
BACKGROUND: Aluminium tubes for pharmaceutical use are internally lacquered with epoxy resins (ER) based on bisphenol A diglycidyl ether (BADGE). Recently, it was shown that remnants of ER polymerization like BADGE are extractable from epoxy-based coatings of commercially available tubes and may leach into semi-solid drug preparations. We aimed to evaluate the safety of BADGE-contaminated macrogol ointments in individuals sensitized to ER based on BADGE by use tests. METHODS: Repeated open application testing (ROAT) in 11 patients sensitized to ER based on BADGE with BADGE in macrogol ointments (3 mg/kg; 30 mg/kg, equivalent to BADGE concentration determined in macrogol ointment after storage in a commercially available tube; 300 mg/kg). RESULTS: The 30 mg/kg BADGE ointment elicited reactions in three patients, and another three patients reacted to 300 mg/kg BADGE ointment. No reactions to the vehicle control and 3 mg/kg BADGE were observed. CONCLUSIONS: Elevated BADGE concentrations in ER-coated aluminium tubes pose a risk of developing contact dermatitis to patients sensitized to ER based on BADGE. Quality standards are deemed necessary for the production of ER-coated aluminium tubes intended for pharmaceutical use and should consider the results of the present ROAT study.
Descriptors
Links
Book Title
Database
Publisher
John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Data Source
Authors
Breuer,K., Lipperheide,C., Lipke,U., Zapf,T., Dickel,H., Treudler,R., Molin,S., Mahler,V., Pfohler,C., Loffler,H., Schwantes,H., Schnuch,A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors