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Title Sort descending	Pub Year	Author	SearchLink
Simultaneous analysis of phthalates, adipate and polycyclic aromatic hydrocarbons in edible oils using isotope dilution-gas chromatography-mass spectrometry	2014	a Advanced Analysis Center, Korea Institute of Science and Technology , Seoul , Republic of Korea.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Food additives & contaminants.Part B, Surveillance Periodical, Abbrev. Food Addit Contam.Part B.Surveill. Pub Date Free Form Volume 7 Issue 3 Start Page 168 Other Pages 175 Notes LR: 20160518; JID: 101317183; 0 (Adipates); 0 (Isotopes); 0 (Phthalic Acids); 0 (Plant Oils); 0 (Polycyclic Hydrocarbons, Aromatic); 6O7F7IX66E (phthalic acid); 76A0JE0FKJ (adipic acid); OTO: NOTNLM; 2014/02/05 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1939-3229; 1939-3210 Accession Number PMID: 25029399 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1080/19393210.2013.869770 [doi] Output Language Unknown(0) PMID 25029399 Abstract A method for simultaneous determination of 12 priority phthalates, adipate and polycyclic aromatic hydrocarbons (PAHs) in edible oils by isotope dilution-gas chromatography-mass spectrometry (ID-GC-MS) was developed for fast, accurate and trace analysis. The extraction and clean-up procedures were optimised, and using stable isotope-labelled internal standards for each analyte, relative standard deviations (RSDs) of 0.92-10.6% and spiked sample recoveries of 80.6-97.8% were obtained. Limits of detection for PAHs were in the range of 0.15-0.77 microg/kg and those for phthalates were in the range of 4.6-10.0 microg/kg. The calibration curves exhibited good linearities with regression coefficients of R(2) >/= 0.99. Twelve edible oils were examined to evaluate the efficiency of this method. Among the 12 analytes, dibutyl phthalates (DBP), diethylhexyl phthalates (DEHP), diethylhexyl adipate (DEHA), benzo[a]anthracene (B[a]A), chrysene (Chry) and benzo[b]fluoranthene (B[b]F) were detected in the range of 1.17-806 microg/kg. Descriptors Links Book Title Database Publisher Data Source Authors Oh,M.S., Lee,S.H., Moon,M.H., Lee,D.S., Park,H.M. Original/Translated Title URL Date of Electronic 20140205 PMCID Editors
Simultaneous determination of NOGE-related and BADGE-related compounds in canned food by ultra-performance liquid chromatography-tandem mass spectrometry	2010	School of Food Science and Biotechnology Engineering, Zhejiang Gongshang University, Hangzhou 310035, China. hongzh1316@mail.zjgsu.edu.cn	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Analytical and bioanalytical chemistry Periodical, Abbrev. Anal.Bioanal Chem. Pub Date Free Form Dec Volume 398 Issue 8-Jul Start Page 3165 Other Pages 3174 Notes LR: 20160512; JID: 101134327; 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (Phenyl Ethers); 0 (novolac glycidyl ether); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); 2010/08/17 [received]; 2010/09/29 [accepted]; 2010/09/24 [revised]; 2010/10/15 [a Place of Publication Germany ISSN/ISBN 1618-2650; 1618-2642 Accession Number PMID: 20953767 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1007/s00216-010-4284-5 [doi] Output Language Unknown(0) PMID 20953767 Abstract An improved analytical method enabling rapid and accurate determination and identification of bisphenol F diglycidyl ether (novolac glycidyl ether 2-ring), novolac glycidyl ether 3-ring, novolac glycidyl ether 4-ring, novolac glycidyl ether 5-ring, novolac glycidyl ether 6-ring, bisphenol A diglycidyl ether, bisphenol A (2,3-dihydroxypropyl) glycidyl ether, bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether, bisphenol A bis(3-chloro-2-hydroxypropyl) ether, and bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether in canned food and their contact packaging materials has been developed by using, for the first time, ultra-performance liquid chromatography coupled with tandem mass spectrometry. After comparison of electrospray ionization and atmospheric pressure chemical ionization in positive and negative-ion modes, tandem mass spectrometry with positive electrospray ionization was chosen to carry out selective multiple reaction monitoring analysis of novolac glycidyl ethers, bisphenol A diglycidyl ether, and its derivatives. The analysis time is only 5.5 min per run. Limits of detection varied from 0.01 to 0.20 ng g(-1) for the different target compounds on the basis of a signal-to-noise ratio (S/N) = 3; limits of quantitation were from 0.03 to 0.66 ng g(-1). The relative standard deviation for repeatability was <8.01%. Analytical recovery ranged from 87.60 to 108.93%. This method was successfully applied to twenty samples of canned food and their contact packaging materials for determination of migration of NOGE, BADGE, and their derivatives from can coatings into food. Descriptors Benzhydryl Compounds, Chromatography, Liquid/methods, Epoxy Compounds/analysis, Food, Preserved/analysis, Linear Models, Phenyl Ethers/analysis, Reproducibility of Results, Spectrometry, Mass, Electrospray Ionization/methods, Tandem Mass Spectrometry/methods Links Book Title Database Publisher Data Source Authors Zhang,H., Xue,M., Zou,Y., Dai,Z., Lin,K. Original/Translated Title URL Date of Electronic 20101015 PMCID Editors
Simultaneous determination of pesticides, polycyclic aromatic hydrocarbons and polychlorinated biphenyls in seawater and interstitial marine water samples, using stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry	2007	Departamento de Quimica Fisica, Facultad de Ciencias del Mar y Ambientales, Universidad de Cadiz, Campus Rio San Pedro s/n 11510 Puerto Real, Cadiz, Spain.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 2-Nov Volume 1170 Issue 2-Jan Start Page 82 Other Pages 90 Notes LR: 20131121; JID: 9318488; 0 (Pesticide Residues); 0 (Pesticides); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); DFC2HB4I0K (Polychlorinated Biphenyls); 2007/06/14 [received]; 2007/ Place of Publication Netherlands ISSN/ISBN 0021-9673; 0021-9673 Accession Number PMID: 17915232 Language eng SubFile Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM DOI S0021-9673(07)01551-8 [pii] Output Language Unknown(0) PMID 17915232 Abstract A method for the simultaneous determination of semi-volatile organic contaminants (polycyclic aromatic hydrocarbons, polychlorinated biphenyls, organochlorine and organophosphorus pesticides) in marine samples has been developed, for the first time, using the stir bar sorptive extraction technique (SBSE) and thermal desorption coupled to capillary gas chromatography-mass spectrometry (SBSE-TD-GC-MS). Polydimethyl siloxane (PDMS) was used for the extraction of the selected analytes and two procedures have been optimised and validated, one for seawater samples (100 mL) and another for interstitial water samples (10 mL), using PDMS stir bars of 20 mm and 10 mm size, respectively. The extraction and analytical conditions, such as extraction time, matrix effects, sample volume and desorption time, were optimised. The proposed methods are sensitive, simple and show good linearity and detection limits lower than 1 ng L(-1) with seawater and lower than 10 ng L(-1) with interstitial marine water for the majority of compounds tested. Repeatability and reproducibility, expressed as relative standard deviation, have values lower than 20% for the majority of analytes considered. The recoveries for both sample volume procedures are higher than 60 and 70% for 10 and 100 mL, respectively, except for the more apolar (some PAHs and PCBs) and the more polar (some triazines) analytes which present lower values. The present SBSE/GC/MS method was applied for the analysis of trace organic contaminants in seawater and interstitial water samples from Cadiz Bay (SW of Spain). Terbutylazine, DDX and some PAHs were found at several seawater sampling points at ng L(-1) levels, and some PAHs in interstitial water too. Descriptors Adsorption, Chemical Fractionation/methods, Dichlorodiphenyl Dichloroethylene/analysis, Gas Chromatography-Mass Spectrometry/instrumentation/methods, Hot Temperature, Pesticide Residues/analysis, Pesticides/analysis, Polychlorinated Biphenyls/analysis, Polycyclic Hydrocarbons, Aromatic/analysis, Reproducibility of Results, Seawater/chemistry, Sensitivity and Specificity, Volatilization, Water Pollutants, Chemical/analysis Links Book Title Database Publisher Data Source Authors Perez-Carrera,E., Leon,V. M., Parra,A. G., Gonzalez-Mazo,E. Original/Translated Title URL Date of Electronic 20070914 PMCID Editors
Simultaneous determination of polycyclic aromatic hydrocarbons and benzene, toluene, ethylbenzene and xylene in water samples using a new sampling strategy combining different extraction modes and temperatures in a single extraction solid-phase microextra	2012	Departamento de Quimica, Universidade Federal de Santa Catarina, Florianopolis 88040900, SC, Brazil.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 13-Apr Volume 1233 Issue Start Page 22 Other Pages 29 Notes LR: 20131121; CI: Copyright (c) 2012; JID: 9318488; 0 (Benzene Derivatives); 0 (Polycyclic Compounds); 0 (Water Pollutants, Chemical); 0 (Xylenes); 3FPU23BG52 (Toluene); J64922108F (Benzene); L5I45M5G0O (ethylbenzene); 2011/12/13 [received]; 2012/02/08 [r Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 22386255 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; Validation Studies; IM DOI 10.1016/j.chroma.2012.02.022 [doi] Output Language Unknown(0) PMID 22386255 Abstract This study proposes a new optimization approach for the simultaneous determination of polycyclic aromatic hydrocarbons (PAHs) and benzene, toluene, ethylbenzene and xylene isomers (BTEX) from water samples using the solid-phase microextraction technique followed by gas chromatography-mass spectrometry (GC-MS) separation and detection. The objective of the study was to achieve compromise extraction conditions, suitable for all semi-volatile and volatile compounds, under which the amount extracted is maximized for all analytes. This was achieved by careful optimization of the fiber coating, salting-out effect, extraction time and temperature and extraction mode (headspace or direct immersion). With the optimized fiber coating - PDMS/DVB 65 mum - the other selected factors were optimized using a response surface methodology through central composite designs. As expected, the optimized results for each class of analytes varied significantly, probably due to the differences in their volatility and the equilibrium constants for the analyte/fiber coating. In order to overcome this issue, a new optimization approach was proposed based on a combination of extraction modes and extraction temperatures in a single extraction procedure. The final optimized procedure was: 48 min of extraction in direct immersion mode with the sample maintained at 80 degrees C followed by a further 32 min of headspace extraction with the sample temperature kept at 10 degrees C. The proposed procedure was compared with conventional methods based on the use of a single extraction mode and temperature (80 min of headspace extraction at 60 degrees C or 80 min of direct immersion extraction at 50 degrees C). The newly proposed method was shown to be more attractive as it extracted higher amounts of both semi-volatile and volatile compounds in a single extraction procedure compared to the conventional approaches. The optimized method was validated and excellent results were obtained. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Bianchin,J.N., Nardini,G., Merib,J., Dias,A.N., Martendal,E., Carasek,E. Original/Translated Title URL Date of Electronic 20120217 PMCID Editors
Simultaneous determination of polycyclic aromatic hydrocarbons and their chlorination by-products in drinking water and the coatings of water pipes by automated solid-phase microextraction followed by gas chromatography-mass spectrometry	2013	ANSES, Nancy Laboratory for Hydrology, Water Chemistry Department, 40 Rue Lionnois, 54 000 Nancy, France. Electronic address: jtillner@live.com.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 8-Nov Volume 1315 Issue Start Page 36 Other Pages 46 Notes CI: Copyright (c) 2013; JID: 9318488; 0 (Acetates); 0 (Drinking Water); 0 (Polycyclic Hydrocarbons, Aromatic); 76845O8NMZ (ethyl acetate); OTO: NOTNLM; 2013/06/11 [received]; 2013/09/13 [revised]; 2013/09/16 [accepted]; 2013/09/19 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 24094751 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2013.09.047 [doi] Output Language Unknown(0) PMID 24094751 Abstract In this study, an automated method for the simultaneous determination of polycyclic aromatic hydrocarbons (PAHs) and their chlorination by-products in drinking water was developed based on online solid-phase microextraction-gas chromatography-mass spectrometry. The main focus was the optimisation of the solid-phase microextraction step. The influence of the agitation rate, type of fibre, desorption time, extraction time, extraction temperature, desorption temperature, and solvent addition was examined. The method was developed and validated using a mixture of 17 PAHs, 11 potential chlorination by-products (chlorinated and oxidised PAHs) and 6 deuterated standards. The limit of quantification was 10 ng/L for all target compounds. The validated method was used to analyse drinking water samples from three different drinking water distribution networks and the presumably coal tar-based pipe coatings of two pipe sections. A number of PAHs were detected in all three networks although individual compositions varied. Several PAH chlorination by-products (anthraquinone, fluorenone, cyclopenta[d,e,f]phenanthrenone, 3-chlorofluoranthene, and 1-chloropyrene) were also found, their presence correlating closely with that of their respective parent compounds. Their concentrations were always below 100 ng/L. In the coatings, all PAHs targeted were detected although concentrations varied between the two coatings (76-12,635 mg/kg and 12-6295 mg/kg, respectively). A number of chlorination by-products (anthraquinone, fluorenone, cyclopenta[d,e,f]phenanthrenone, 3-chlorofluoranthene, and 1-chloropyrene) were also detected (from 40 to 985 mg/kg), suggesting that the reaction of PAHs with disinfectant agents takes place in the coatings and not in the water phase after migration. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Tillner,J., Hollard,C., Bach,C., Rosin,C., Munoz,J.F., Dauchy,X. Original/Translated Title URL Date of Electronic 20130919 PMCID Editors
Simultaneous transport of substrates, disinfectants and microorganisms in water pipes	1995	Lu, C., Department Environmental Engineering, National Chung Hsing University, Taichung 40227, Taiwan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Water research Periodical, Abbrev. Water Res. Pub Date Free Form 1995/ Volume 29 Issue 3 Start Page 881 Other Pages 894 Notes Place of Publication ISSN/ISBN 0043-1354 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract A mathematical model that accounts for simultaneous transport of substrates, disinfectants and microorganisms has been developed to predict substantial changes in quality of distributed water. The model consists of a set of mass balance equations for organic substances, ammonium nitrogen, oxidized nitrogen, dissolved oxygen, alkalinity, biomass, and disinfectants in the bulk liquid phase and within the biofilm under laminar and turbulent flow conditions. This model is validated by comparing its solutions with the numerical solutions in the literature and then is applied for predicting the behavior of a typical water treatment plant effluent through a distribution pipe. The flow properties and disinfectant consumption rate at the pipe wall play a significant role in the determination of potable water quality in the distribution system. Descriptors ammonia, disinfectant agent, dissolved oxygen, nitrogen, organic matter, alkalinity, article, biofilm, biomass, controlled study, effluent, mathematical model, microorganism, priority journal, turbulent flow, water flow, water quality, water transport, water treatment Links Book Title Database Embase Publisher Data Source Embase Authors Lu,C., Biswas,P., Clark,R. M. Original/Translated Title URL Date of Electronic PMCID Editors
Simvastatin inhibits planktonic cells and biofilms of Candida and Cryptococcus species	2015	Centro Especializado em Micologia Medica, Programa de Pos-Graduacao em Microbiologia Medica, Universidade Federal do Ceara (UFC), Fortaleza, CE, Brazil; Programa de Pos-Graduacao em Ciencias Medicas, Universidade Federal do Ceara (UFC), Fortaleza, CE, Bra	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases Periodical, Abbrev. Braz.J.Infect.Dis. Pub Date Free Form Sep-Oct Volume 19 Issue 5 Start Page 459 Other Pages 465 Notes CI: Copyright (c) 2015; JID: 9812937; 0 (Antifungal Agents); 304NUG5GF4 (Itraconazole); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); AGG2FN16EV (Simvastatin); OTO: NOTNLM; 2015/04/02 [received]; 2015/06/01 [revised]; 2015/06/01 [accepted]; 2015/ Place of Publication Brazil ISSN/ISBN 1678-4391; 1413-8670 Accession Number PMID: 26119850 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.bjid.2015.06.001 [doi] Output Language Unknown(0) PMID 26119850 Abstract The antifungal activity of some statins against different fungal species has been reported. Thus, at the first moment, the in vitro antifungal activity of simvastatin, atorvastatin and pravastatin was tested against Candida spp. and Cryptococcus spp. Then, in a second approach, considering that the best results were obtained for simvastatin, this drug was evaluated in combination with antifungal drugs against planktonic growth and tested against biofilms of Candida spp. and Cryptococcus spp. Drug susceptibility testing was performed using the microdilution broth method, as described by the Clinical and Laboratory Standards Institute. The interaction between simvastatin and antifungals against planktonic cells was analyzed by calculating the fractional inhibitory concentration index. Regarding biofilm susceptibility, simvastatin was tested against growing biofilm and mature biofilm of one strain of each tested yeast species. Simvastatin showed inhibitory effect against Candida spp. and Cryptococcus spp. with minimum inhibitory concentration values ranging from 15.6 to 1000 mg L(-1) and from 62.5 to 1000 mg L(-1), respectively. The combination of simvastatin with itraconazole and fluconazole showed synergism against Candida spp. and Cryptococcus spp., while the combination of simvastatin with amphotericin B was synergistic only against Cryptococcus spp. Concerning the biofilm assays, simvastatin was able to inhibit both growing biofilm and mature biofilm of Candida spp. and Cryptococcus spp. The present study showed that simvastatin inhibits planktonic cells and biofilms of Candida and Cryptococcus species. Descriptors Links Book Title Database Publisher Elsevier Editora Ltda Data Source Authors Brilhante,R.S., Caetano,E.P., Oliveira,J.S., Castelo-Branco Dde,S., Souza,E.R., Alencar,L.P., Cordeiro Rde,A., Bandeira Tde,J., Sidrim,J.J., Rocha,M.F. Original/Translated Title URL Date of Electronic 20150626 PMCID Editors
Single laboratory validation of a method for the determination of Bisphenol A, Bisphenol A diglycidyl ether and its derivatives in canned foods by reversed-phase liquid chromatography	2006	Food Science and Technology Programme, Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 29-Sep Volume 1129 Issue 1 Start Page 145 Other Pages 148 Notes LR: 20131121; JID: 9318488; 0 (Acetonitriles); 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (Phenols); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); MLT3645I99 (bisphenol A); Z072SB282N (acetonitrile); 2005/12/20 [received]; 2006/07/31 [revised]; Place of Publication Netherlands ISSN/ISBN 0021-9673; 0021-9673 Accession Number PMID: 16945377 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI S0021-9673(06)01563-9 [pii] Output Language Unknown(0) PMID 16945377 Abstract A method was developed and validated for the simultaneous determination of Bisphenol A (BPA), Bisphenol A diglycidyl ether (BADGE), BADGE-H2O, BADGE-2H2O, BADGE-H2O-HCl, BADGE-HCl, and BADGE-2HCl in canned food using reversed phase high-performance liquid chromatography (HPLC) with fluorescence detection; chromatographic separation of all seven analytes was achieved (Rs > or = 1.08) using HPLC gradient elution technique. Acetonitrile was used to extract the analytes from the food matrix before subjecting the samples to liquid-liquid extraction, solid-phase extraction for further clean-up and preconcentration prior to HPLC analysis. Excellent inter-day precision data (n = 10) and intra-day precision data (n = 5) were obtained on a 200 microg/kg spiked sample. The RSD ranged from 0.20% to 2.96% for the inter-day precision tests, and 0.04% to 2.82% for the intra-day precision tests. Accuracy was measured at three concentration levels: 200, 1000, and 2000 microg/kg; recoveries ranged from 86.07% to 114.06%. The excellent validation data suggests that this method can be applied on canned foods for the determination of migration of BPA, BADGE and its derivatives from can coatings into food. Descriptors Acetonitriles/chemistry, Benzhydryl Compounds, Chromatography, High Pressure Liquid/methods, Epoxy Compounds/analysis/chemistry/isolation & purification, Food Analysis/methods, Food Contamination/analysis, Food Preservation, Phenols/analysis/chemistry/isolation & purification, Reproducibility of Results Links Book Title Database Publisher Data Source Authors Sun,C., Leong,L. P., Barlow,P. J., Chan,S. H., Bloodworth,B. C. Original/Translated Title URL Date of Electronic 20060901 PMCID Editors
Six-minute walk distance in healthy Singaporean adults cannot be predicted using reference equations derived from Caucasian populations	2006	School of Physiotherapy, Curtin University of Technology, Perth, Western Australia, Australia.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Respirology (Carlton, Vic.) Periodical, Abbrev. Respirology Pub Date Free Form Mar Volume 11 Issue 2 Start Page 211 Other Pages 216 Notes LR: 20061115; JID: 9616368; CIN: Respirology. 2006 Sep;11(5):669-70; author reply 671-2. PMID: 16916347; ppublish Place of Publication Australia ISSN/ISBN 1323-7799; 1323-7799 Accession Number PMID: 16548908 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI RES [pii] Output Language Unknown(0) PMID 16548908 Abstract OBJECTIVES: The 6-min walk test (6MWT) is commonly used to assess the functional exercise capacity of individuals with cardiopulmonary disease. Recent studies have established regression equations to predict the 6-min walk distance (6MWD) in healthy Caucasian populations; however, regression equations have yet to be established for the Singaporean population. The aim of this study was to determine 6MWD in healthy Singaporeans and identify contributors to 6MWD in this population. We also compared measured 6MWD with predicted 6MWD from two regression equations derived in Caucasian subjects. METHODOLOGY: Thirty-five healthy subjects (32 Chinese, 16 men) aged between 45 and 85 years performed three walking tests using a standardized protocol. 6MWD was defined as the greatest distance achieved from the three tests. Heart rate (HR) was recorded each minute during the 6MWT. Other measurements included age, height, leg length, smoking history and self-reported physical activity. RESULTS: 6MWD was 560 +/- 105 m and was not significantly different between men and women (P = 0.19). 6MWD was related to age (r = -0.36, P = 0.03), height (r = 0.35, P = 0.04), leg length (r = 0.38, P = 0.02) and the maximum HR achieved on the 6MWT when expressed as a percentage of the predicted maximum HR (%predHRmax, r = 0.73, P < 0.001). Stepwise multiple regression analysis showed that age, height, weight and %predHRmax were independent contributors (P < 0.01) to 6MWD, explaining 78% of the variance. Predicted 6MWD using regression equations derived from Caucasian subjects exceeded measured 6MWD by more than 75 m (P < 0.001). CONCLUSIONS: This is the first study to report 6MWD for healthy Singaporeans aged 45-85 years. The regression equation developed in this study explained 78% of the variance in 6MWD. Published equations derived from Caucasian subjects overestimate 6MWD in Singaporean Chinese. Descriptors Aged, Aged, 80 and over, Asian Continental Ancestry Group, Body Composition, European Continental Ancestry Group, Exercise Test/standards, Female, Heart Rate, Humans, Male, Middle Aged, Reference Standards, Reference Values, Singapore, Spirometry, Walking/physiology Links Book Title Database Publisher Data Source Authors Poh,H., Eastwood,P. R., Cecins,N. M., Ho,K. T., Jenkins,S. C. Original/Translated Title URL Date of Electronic PMCID Editors
Six-minute walk distance is not related to quality of life in patients with non-cystic fibrosis bronchiectasis	2012	Programa de Pos-Graduacao em Ciencias Pneumologicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia Periodical, Abbrev. J.Bras.Pneumol. Pub Date Free Form May-Jun Volume 38 Issue 3 Start Page 346 Other Pages 355 Notes LR: 20130926; JID: 101222274; 2012/01/30 [received]; 2012/03/08 [accepted]; ppublish Place of Publication Brazil ISSN/ISBN 1806-3756; 1806-3713 Accession Number PMID: 22782605 Language eng; por SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI S1806-37132012000300010 [pii] Output Language Unknown(0) PMID 22782605 Abstract OBJECTIVE: To evaluate physical performance on the six-minute walk test (6MWT) in patients with non-cystic fibrosis bronchiectasis and to investigate its relationship with quality of life (QoL). To identify predictors of exercise performance, we also investigated whether six-minute walk distance (6MWD) is associated with clinical and spirometric findings. METHODS: This was a cross-sectional study involving patients with non-cystic fibrosis bronchiectasis (age, > 18 years), with at least one respiratory symptom for > 2 years and an FEV1 Descriptors Links Book Title Database Publisher Data Source Authors Jacques,P.S., Gazzana,M.B., Palombini,D.V., Barreto,S.S., Dalcin Pde,T. Original/Translated Title URL Date of Electronic PMCID Editors

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