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Relation of cardiovascular risk factors and angina status to obstructive coronary artery disease according to categorical coronary artery calcium score 2012 Department of Cardiology, Sumitomo Hospital, 5-3-20 Nakanoshima, Kita-ku, Osaka 530-0005, Japan. ueda-hiroyasu@sumitomo-hp.or.jp
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Heart and vessels
Periodical, Abbrev.
Heart Vessels
Pub Date Free Form
Mar
Volume
27
Issue
2
Start Page
128
Other Pages
134
Notes
JID: 8511258; 2010/09/21 [received]; 2011/02/18 [accepted]; 2011/03/18 [aheadofprint]; ppublish
Place of Publication
Japan
ISSN/ISBN
1615-2573; 0910-8327
Accession Number
PMID: 21416117
Language
eng
SubFile
Journal Article; IM
DOI
10.1007/s00380-011-0128-2 [doi]
Output Language
Unknown(0)
PMID
21416117
Abstract
Coronary artery calcium (CAC) is associated with the presence of coronary artery disease (CAD) and cardiovascular risk factors. However, the relation between cardiovascular risk factors and CAD has not yet been fully elucidated in patients with a zero or low coronary artery calcium score (CACS). The purpose of this study was to evaluate the relation of cardiovascular risk factors and angina status to obstructive CAD according to categorical CACS. A total of 753 patients were enrolled in this study. CAC scoring and coronary computed tomographic angiography (CCTA) were performed with dual-source 64-slice CT scanners. The number of patients with a CACS =10 and =100 were 358 and 528, respectively. Patients with a higher CACS were older and more frequently male, and had a greater frequency of hypertension, diabetes, and hypercholesterolemia. The prevalence of obstructive CAD increased with the CACS. Among patients with a CACS =100, age, male gender, diabetes, hypercholesterolemia, and typical angina pectoris were related to obstructive CAD. The presence of hypercholesterolemia was relatively strongly associated with obstructive CAD (OR 6.67, 95% CI 2.91-15.3, p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Ueda,H., Harimoto,K., Tomoyama,S., Tamaru,H., Miyawaki,M., Mitsusada,N., Yasuga,Y., Hiraoka,H.
Original/Translated Title
URL
Date of Electronic
20110318
PMCID
Editors
Relation of exercise capacity with lung volumes before and after 6-minute walk test in subjects with COPD 2014 Department of Internal Medicine II, University Hospital of Ulm, Ulm, Germany. thomas.wibmer@gmx.de.; Department of Internal Medicine II, University Hospital of Ulm, Ulm, Germany.; Department of Internal Medicine II, University Hospital of Ulm, Ulm, German
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Respiratory care
Periodical, Abbrev.
Respir.Care
Pub Date Free Form
Nov
Volume
59
Issue
11
Start Page
1687
Other Pages
1695
Notes
CI: Copyright (c) 2014; JID: 7510357; OTO: NOTNLM; 2014/09/23 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1943-3654; 0020-1324
Accession Number
PMID: 25249649
Language
eng
SubFile
Journal Article; IM
DOI
10.4187/respcare.03082 [doi]
Output Language
Unknown(0)
PMID
25249649
Abstract
INTRODUCTION: There is growing evidence that exercise-induced variation in lung volumes is an important source of ventilatory limitation and is linked to exercise intolerance in COPD. The aim of this study was to compare the correlations of walk distance and lung volumes measured before and after a 6-min walk test (6MWT) in subjects with COPD. METHODS: Forty-five subjects with stable COPD (mean pre-bronchodilator FEV1: 47 +/- 18% predicted) underwent a 6MWT. Body plethysmography was performed immediately pre- and post-6MWT. RESULTS: Correlations were generally stronger between 6-min walk distance and post-6MWT lung volumes than between 6-min walk distance and pre-6MWT lung volumes, except for FEV1. These differences in Pearson correlation coefficients were significant for residual volume expressed as percent of total lung capacity (-0.67 vs -0.58, P = .043), percent of predicted residual volume expressed as percent of total lung capacity (-0.68 vs -0.59, P = .026), inspiratory vital capacity (0.65 vs 0.54, P = .019), percent of predicted inspiratory vital capacity (0.49 vs 0.38, P = .037), and percent of predicted functional residual capacity (-0.62 vs -0.47, P = .023). CONCLUSIONS: In subjects with stable COPD, lung volumes measured immediately after 6MWT are more closely related to exercise limitation than baseline lung volumes measured before 6MWT, except for FEV1. Therefore, pulmonary function testing immediately after exercise should be included in future studies on COPD for the assessment of exercise-induced ventilatory constraints to physical performance that cannot be adequately assessed from baseline pulmonary function testing at rest.
Descriptors
Links
Book Title
Database
Publisher
by Daedalus Enterprises
Data Source
Authors
Wibmer,T., Rudiger,S., Kropf-Sanchen,C., Stoiber,K.M., Rottbauer,W., Schumann,C.
Original/Translated Title
URL
Date of Electronic
20140923
PMCID
Editors
Relation of radon exposure and tobacco use to lung cancer among tin miners in Yunnan Province, China 1989 Department of Epidemiology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing 100021
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Industrial Medicine
Periodical, Abbrev.
Am.J.Ind.Med.
Pub Date Free Form
1989/
Volume
16
Issue
5
Start Page
511
Other Pages
521
Notes
Place of Publication
ISSN/ISBN
0271-3586
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
We studied the relation of radon exposure and tobacco use to lung cancer among tin miners in Yunnan Province in the People's Republic of China. Interviews were conducted in 1985 with 107 living tin miners with lung cancer and an equal number of age-matched controls from among tin miners without lung cancer to obtain information on lung cancer risk factors including a detailed history of employment and tobacco use. Occupational history was combined with extensive industrial hygiene data to estimate cumulative working level months (WLM) of radon daughter exposure. Similar data were also used to estimate arsenic exposure for control in the analysis. Results indicate an increased risk of lung cancer for water pipe smoking, a traditional form of tobacco use practiced in 91% of cases and 85% of controls. Ever use of water pipes was associated with a twofold elevation in risk when compared with tobacco abstainers, and a dose-response relation was observed with increasing categories of pipe-year (dose times duration) usage. Estimated WLM of radon exposure varied from 0 to 1,761 among subjects but averaged 515 in cases versus only 244 in controls. Analyses indicated that the persons in the highest quarter of the radon exposure distribution had an odds ratio (OR) = 9.5 (95% confidence interval = 2.7-33.1) compared to persons without radon exposure after controlling for arsenic exposure and other potential confounders. Examination of duration and rate of radon exposure indicated higher risk associated with long duration as opposed to high rate of exposure. Cross-categorizations of radon exposure and tobacco use suggest greater risk associated with radon exposure than tobacco in these workers.
Descriptors
radon, tin, adult, aged, article, China, epidemiology, etiology, human, lung cancer, major clinical study, male, occupational exposure, tobacco
Links
Book Title
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
Qiao,Y. -L, Taylor,P. R., Yao,S. -X, Schatzkin,A., Mao,B. -L, Lubin,J., Rao,J. -Y, McAdams,M., Xuan,X. -Z, Li,J. -Y
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Relationship between adherence to daily nicotine patch use and treatment efficacy: secondary analysis of a 10-week randomized, double-blind, placebo-controlled clinical trial simulating over-the-counter use in adult smokers 2008 PinneyAssociates, Inc., Pittsburgh, Pennsylvania 15213, USA. shiffman@pinneyassociates.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Clinical therapeutics
Periodical, Abbrev.
Clin.Ther.
Pub Date Free Form
Oct
Volume
30
Issue
10
Start Page
1852
Other Pages
1858
Notes
LR: 20151119; JID: 7706726; 0 (Nicotinic Agonists); 0 (Nonprescription Drugs); 6M3C89ZY6R (Nicotine); 2008/08/21 [accepted]; ppublish
Place of Publication
United States
ISSN/ISBN
0149-2918; 0149-2918
Accession Number
PMID: 19014840
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.clinthera.2008.09.016 [doi]
Output Language
Unknown(0)
PMID
19014840
Abstract
BACKGROUND: It has been reported that the efficacy of acute forms of nicotine replacement therapy, such as nicotine gum and lozenges, improves when sufficient quantities of medication are used. OBJECTIVE: This analysis examined whether adherence with daily nicotine patch wear was associated with improved rates of smoking abstinence. METHODS: This was a secondary analysis of data from a double-blind study in which subjects were randomized to receive either an active nicotine patch or a placebo patch under simulated over-the-counter conditions. Subjects were asked to complete a daily diary on their patch use and smoking. Logistic regression, controlling for smoking in the first 3 weeks of treatment, was used to evaluate the likelihood of abstinence at 6 weeks as a function of treatment assignment (active vs placebo) and adherence (ie, patch wear for >or=20 of the first 21 days of treatment). The relationship between reported adverse events and adherence was also examined. RESULTS: This analysis involved data from 371 subjects, 204 using the active patch and 167 using the placebo patch. The study population was mainly white (87.3%), had a mean age of 42.8 years, a mean weight of 77.3 kg, had been smoking for a mean of 24.4 years, and smoked a mean of 25.2 cigarettes per day. Two hundred fifty-three subjects were classified as adherent. Rates of adherence did not differ significantly between the active and placebo groups (139 [68.1%] and 114 [68.3%], respectively). The likelihood of experiencing an adverse event did not differ significantly between adherent and nonadherent subjects in either group. Among active patch users, 61.5% of nonadherent subjects experienced an adverse event, compared with 59.7% of adherent subjects; among placebo patch users, the corresponding proportions were 41.5% and 43.9%. Among active patch users, the odds of abstinence at 6 weeks were more than 3 times greater for adherent versus nonadherent subjects (53.2% vs 21.5%, respectively; adjusted odds ratio [OR] = 3.25; 95% CI, 1.30-8.09; P = 0.011); no benefit of adherence over nonadherence was seen among users of the placebo patch (16.7% vs 15.1%; adjusted OR = 0.60; 95% CI, 0.16-2.31). The interaction between treatment group and adherence was statistically significant (P = 0.022). CONCLUSION: Under conditions simulating over-the-counter use, adherence to daily nicotine patch wear within the first 3 weeks of treatment was associated with an improved likelihood of achieving smoking abstinence at 6 weeks.
Descriptors
Administration, Cutaneous, Adult, Double-Blind Method, Female, Humans, Male, Medication Adherence, Nicotine/administration & dosage/therapeutic use, Nicotinic Agonists/administration & dosage/therapeutic use, Nonprescription Drugs, Smoking Cessation/methods, Socioeconomic Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Shiffman,S., Sweeney,C. T., Ferguson,S. G., Sembower,M. A., Gitchell,J. G.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Relationship between amount of cigarette smoking and coronary atherosclerosis on coronary CTA in asymptomatic individuals 2013 Division of Cardiovascular Imaging, Department of Radiology, Seoul National University Bundang Hospital, Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Korea.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The international journal of cardiovascular imaging
Periodical, Abbrev.
Int.J.Cardiovasc.Imaging
Pub Date Free Form
Jun
Volume
29 Suppl 1
Issue
Start Page
21
Other Pages
28
Notes
JID: 100969716; 2013/03/15 [received]; 2013/04/19 [accepted]; 2013/04/27 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1875-8312; 1569-5794
Accession Number
PMID: 23624929
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s10554-013-0224-8 [doi]
Output Language
Unknown(0)
PMID
23624929
Abstract
Current smoking is a powerful independent predictor of coronary atherosclerosis in asymptomatic individuals. Many researchers have suggested a cigarette dose-response relationship between smoking and subclinical coronary atherosclerosis. Our study purposes were (a) to investigate the prevalence and plaque characteristics of coronary atherosclerosis in asymptomatic smokers and (b) to assess the cigarette dose-response relationship between smoking and subclinical coronary atherosclerosis using coronary CT angiography (CTA). We consecutively enrolled 7,104 self-referred asymptomatic subjects who underwent coronary CTA as part of a general health evaluation. Current smokers (n = 1,784) were categorized according to total pack years (TPY) with four grades (A, 0.1-10; B, 10-20; C, 20-30; D, >30), smoking duration (SD, years) with four grades (A, 0.1-10; B, 10-20; C, 20-30; D, >30), and number of cigarettes per day (CPD) with four grades (A, 1-20; B, 10-20; C, 20-40; D, >40). After adjusting for other cardiovascular risk factors, adjusted odds ratios for current smokers versus never-smokers as a control group were estimated for the presence of plaques, significant stenosis, and non-calcified plaques (NCP). Current smokers had a statistically significant higher prevalence of any plaque, significant stenosis, NCP, and coronary artery calcium score >100 than never-smokers. According to each categorization of TPY, SD, and CPD, the subclinical coronary atherosclerosis risk increased as grades increased in asymptomatic current smokers relative to never-smokers after adjusting for variable clinical and chemical risk factors. Our study suggests a cigarette dose-response relationship between current smoking and coronary atherosclerosis in asymptomatic individuals.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Kim,J.A., Chun,E.J., Lee,M.S., Kim,K.J., Choi,S.I.
Original/Translated Title
URL
Date of Electronic
20130427
PMCID
Editors
Relationship between Carboxyhemoglobin Levels and Hematological Values in Sheesha Smokers 1989
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Saudi Med J
Periodical, Abbrev.
Saudi Med.J.
Pub Date Free Form
Volume
10
Issue
5
Start Page
372
Other Pages
378
Notes
ID: 17036
Place of Publication
ISSN/ISBN
Accession Number
Language
english
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
The relationships between haemoglobin concentration Hb], haematocrit HCT] and carboxyhaemoglobin COHb] levels were investigated in 186 sheesha, and 155 cigarette smokers and 132 non-smokers. Both mean Hb and HCT values were found to be significantly higher in sheesha smokers of all age groups p<0.001], heavy cigarette smokers aged 40 to 49 years p<0.05] and light plus heavy cigarette smokers aged 50-65 years. Carboxyhaemoglobin levels were higher in sheesha than cigarette smokers. Positive correlations were found between COHb levels and that of HCTvalues in both sheesha and cigarette smokers. In seven out of twelve sheesha smokers investigated, the red cell mass was normal while Plasma volume was decreased in ten subjects. It seems that relative rather than absolute polycythaemia is the rule in sheesha smokers. These findings cast doubt on the extent of the relationship between carbon monoxide and erythrocytosis
Descriptors
Smoking, Carboxyhemoglobin, Hematologic Tests
Links
http://pesquisa.bvsalud.org/ghl/resource/en/emro-17036
Book Title
Database
GHL; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Al Fayez,Saud F.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Relationship between chronic obstructive pulmonary disease and subclinical coronary artery disease in long-term smokers 2013 Department of Cardiology, Section 2012, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
European heart journal cardiovascular Imaging
Periodical, Abbrev.
Eur.Heart J.Cardiovasc.Imaging
Pub Date Free Form
Dec
Volume
14
Issue
12
Start Page
1159
Other Pages
1166
Notes
LR: 20160511; JID: 101573788; OTO: NOTNLM; 2013/05/02 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
2047-2412; 2047-2404
Accession Number
PMID: 23639550
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/ehjci/jet057 [doi]
Output Language
Unknown(0)
PMID
23639550
Abstract
AIMS: Cardiovascular conditions are reported to be the most frequent cause of death in patients with chronic obstructive pulmonary disease (COPD). However, it remains unsettled whether severity of COPD per se is associated with coronary artery disease (CAD) independent of traditional cardiovascular risk factors. The aim of this study was to examine the relationship between the presence and severity of COPD and the amount of coronary artery calcium deposit, an indicator of CAD and cardiac risk, in a large population of current and former long-term smokers. METHODS AND RESULTS: In this cross-sectional study, long-term smokers without clinically manifested CAD were recruited from the Danish Lung Cancer Screening Trial and classified according to lung function by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. Coronary artery calcium deposit as a measure of subclinical CAD and cardiac risk was evaluated with multi detector computed tomography and the Agatston coronary artery calcium score (CACS). Participants were categorized into five CACS risk classification groups according to the CACS. The population (n = 1535) consisted of 41% participants without COPD, 28% with mild, and 31% with moderate-to-severe COPD (n = 46 with severe COPD). In addition to age, male gender, hypertension, hypercholesterolaemia, and continued smoking, COPD according to GOLD classification were independent predictors of a higher CACS risk classification group in multivariable analysis [odds ratio (OR): 1.28 (1.01-1.63) and OR: 1.32 (1.05-1.67), for mild and moderate-to-severe COPD, respectively, compared with no COPD]. CONCLUSION: COPD in long-term smokers is independently correlated with the CACS, while COPD severity per se does not show a dose-response relationship.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Rasmussen,T., Kober,L., Pedersen,J.H., Dirksen,A., Thomsen,L.H., Stender,S., Brodersen,J., Groen,J., Ashraf,H., Kofoed,K.F.
Original/Translated Title
URL
Date of Electronic
20130502
PMCID
Editors
Relationship between cigarette, smokeless tobacco, and cigar use, and other health risk behaviors among U.S. high school students 2000 Division of Adolescent and School Health, USA. sce2@cdc.gov
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of school health
Periodical, Abbrev.
J.Sch.Health
Pub Date Free Form
Aug
Volume
70
Issue
6
Start Page
234
Other Pages
240
Notes
LR: 20151119; JID: 0376370; ppublish
Place of Publication
UNITED STATES
ISSN/ISBN
0022-4391; 0022-4391
Accession Number
PMID: 10937370
Language
eng
SubFile
Comparative Study; Journal Article; IM; N
DOI
Output Language
Unknown(0)
PMID
10937370
Abstract
This study examined relationships between tobacco use and use of other substances, intentional injury risk behaviors, and sexual risk behaviors among US high school students. Data about tobacco use and other health risk behaviors were analyzed from the 1997 national Youth Risk Behavior Survey implemented by the Centers for Disease Control and Prevention. One-fourth of students (24%) reported current use of a single tobacco product (i.e., cigarettes, smokeless tobacco, or cigars during the 30 days preceding the survey), and 19.5% reported currently using more than one tobacco product. Generally, students who reported current tobacco use also reported engaging in other substance use, intentional injury risk behaviors, and sexual risk behaviors. For many risk behaviors, these results were especially pronounced among students who reported using two or all three tobacco products. Programs designed to prevent tobacco use should consider that such use often occurs concomitantly with other health risk behaviors.
Descriptors
Adolescent, Adolescent Behavior, Cocaine-Related Disorders/epidemiology, Female, Humans, Male, Marijuana Abuse/epidemiology, Plants, Toxic, Risk-Taking, Sexual Behavior, Smoking/epidemiology, Substance-Related Disorders/epidemiology, Surveys and Questionnaires, Tobacco Use Disorder/epidemiology, Tobacco, Smokeless, United States/epidemiology
Links
Book Title
Database
Publisher
Data Source
Authors
Everett,S. A., Malarcher,A. M., Sharp,D. J., Husten,C. G., Giovino,G. A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Relationship between increases in BMI and changes in periodontal status: a prospective cohort study 2014 Departments of Preventive Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of clinical periodontology
Periodical, Abbrev.
J.Clin.Periodontol.
Pub Date Free Form
Aug
Volume
41
Issue
8
Start Page
772
Other Pages
778
Notes
CI: (c) 2014; JID: 0425123; OTO: NOTNLM; 2014/05/03 [accepted]; 2014/06/30 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1600-051X; 0303-6979
Accession Number
PMID: 24813869
Language
eng
SubFile
Journal Article; D; IM
DOI
10.1111/jcpe.12273 [doi]
Output Language
Unknown(0)
PMID
24813869
Abstract
AIM: The purpose of this prospective cohort study was to investigate whether body mass index (BMI) and oral health behaviour are related to changes in periodontal status in Japanese university students. MATERIALS AND METHODS: Students (n = 224) who were interested in receiving oral health examinations before entering university and before graduation were included in the analysis. Subjects were investigated regarding the correlations of oral health behaviours and increases in BMI with the percentage of bleeding on probing (%BOP) and Community Periodontal Index (CPI) scores as indicators of changes in periodontal status. RESULTS: The risk of increased %BOP was associated with the non-use of dental floss (adjusted odds ratio [OR]: 3.11; 95% confidence interval [CI]: 1.31-7.37; p
Descriptors
Links
Book Title
Database
Publisher
John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Data Source
Authors
Ekuni,D., Mizutani,S., Kojima,A., Tomofuji,T., Irie,K., Azuma,T., Yoneda,T., Furuta,M., Eshima,N., Iwasaki,Y., Morita,M.
Original/Translated Title
URL
Date of Electronic
20140630
PMCID
Editors
Relationship between right-to-left shunts and cutaneous decompression illness 2001 The Royal Shrewsbury Hospital, Shrewsbury SY3 8XQ, UK.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Clinical science (London, England : 1979)
Periodical, Abbrev.
Clin.Sci.(Lond)
Pub Date Free Form
May
Volume
100
Issue
5
Start Page
539
Other Pages
542
Notes
LR: 20041117; JID: 7905731; ppublish
Place of Publication
England
ISSN/ISBN
0143-5221; 0143-5221
Accession Number
PMID: 11294694
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
11294694
Abstract
The presence of a large right-to-left shunt is associated with neurological decompression illness after non-provocative dives, as a result of paradoxical gas embolism. A small number of observations suggest that cutaneous decompression illness is also associated with a right-to-left shunt, although an embolic aetiology of a diffuse rash is more difficult to explain. We performed a retrospective case--control comparison of the prevalence and sizes of right-to-left shunts determined by contrast echocardiography performed blind to history in 60 divers and one caisson worker with a history of cutaneous decompression illness, and 123 historical control divers. We found that 47 (77.0%) of the 61 cases with cutaneous decompression illness had a shunt, compared with 34 (27.6%) of 123 control divers (P<0.001). The size of the shunts in the divers with cutaneous decompression illness was significantly greater than in the controls. Thus 30 (49.2%) of the 61 cases with cutaneous decompression illness had a large shunt at rest, compared with six (4.9%) of the 123 controls (P<0.001). During closure procedures in 17 divers who had cutaneous decompression illness, the mean diameter of the foramen ovale was 10.9 mm. Cutaneous decompression illness occurred after dives that were provocative or deep in subjects without shunts, but after shallower and non-provocative dives in those with shunts. The latter individuals are at increased risk of neurological decompression illness. We conclude that cutaneous decompression illness has two pathophysiological mechanisms. It is usually associated with a large right-to-left shunt, when the mechanism is likely to be paradoxical gas embolism with peripheral amplification when bubble emboli invade tissues supersaturated with nitrogen. Cutaneous decompression illness can also occur in individuals without a shunt. In these subjects, the mechanism might be bubble emboli passing through an 'overloaded' lung filter or autochthonous bubble formation.
Descriptors
Case-Control Studies, Decompression Sickness/etiology, Female, Heart Septal Defects, Atrial/complications/surgery/ultrasonography, Humans, Male, Retrospective Studies, Skin Diseases/etiology, Valsalva Maneuver/physiology
Links
Book Title
Database
Publisher
Data Source
Authors
Wilmshurst,P. T., Pearson,M. J., Walsh,K. P., Morrison,W. L., Bryson,P.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors