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Evaluation of microtensile and tensile bond strength tests determining effects of erbium, chromium: yttrium-scandium-gallium-garnet laser pulse frequency on resin-enamel bonding 2016 Department of Restorative Dentistry, Faculty of Dentsitry, Karadeniz Technical University, Trabzon, Turkey.; Department of Restorative Dentistry, Faculty of Dentsitry, Biruni University, Istanbul, Turkey.; Department of Restorative Dentistry, Faculty of D
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nigerian journal of clinical practice
Periodical, Abbrev.
Niger.J.Clin.Pract.
Pub Date Free Form
Sep-Oct
Volume
19
Issue
5
Start Page
585
Other Pages
590
Notes
JID: 101150032; ppublish
Place of Publication
India
ISSN/ISBN
1119-3077
Accession Number
PMID: 27538544
Language
eng
SubFile
Journal Article; IM
DOI
10.4103/1119-3077.188702 [doi]
Output Language
Unknown(0)
PMID
27538544
Abstract
OBJECTIVES: The aim of the present study was to compare two different bond strength test methods (tensile and microtensile) in investing the influence of erbium, chromium: yttrium-scandium-gallium-garnet (Er, Cr: YSGG) laser pulse frequency on resin-enamel bonding. MATERIALS AND METHODS: One-hundred and twenty-five bovine incisors were used in the present study. Two test methods were used: Tensile bond strength (TBS; n = 20) and micro-TBS (muTBS; n = 5). Those two groups were further split into three subgroups according to Er, Cr: YSGG laser frequency (20, 35, and 50 Hz). Following adhesive procedures, microhybrid composite was placed in a custom-made bonding jig for TBS testing and incrementally for muTBS testing. TBS and muTBS tests were carried out using a universal testing machine and a microtensile tester, respectively. RESULTS: Analysis of TBS results showed that means were not significantly different. For muTBS, the Laser-50 Hz group showed the highest bond strength (P
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Book Title
Database
Publisher
Data Source
Authors
Yildirim,T., Ayar,M.K., Yesilyurt,C., Kilic,S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Evaluation of occupational health hazards associated with inks used in printing processes at Jang Group of Newspapers, Lahore 2007 Bhatti, A.M., Health Services, EPI, Punjab, Lahore
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Medical Forum Monthly
Periodical, Abbrev.
Med.Forum Monthly
Pub Date Free Form
/
Volume
18
Issue
7
Start Page
10
Other Pages
13
Notes
Place of Publication
ISSN/ISBN
1029-385X
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Introduction:- Mutual communication requires a media and printing is one of the effective and easily diffusible media for communication. During the last few years, revolutionary changes have taken place in communication technology. It is essential for the expansion and development of education and for dissemination of all theories, ideas, inventions and discoveries of mankind. Objective:- To evaluate the occupational health hazards associated with inks used in printing processes at Jang Group of Newspapers, Lahore. Material and methods:- This cross sectional study was conducted on 50 workers who were directly in the use of ink during the period from 1999 to 2000. The concentrations of various chemical are estimated with the help of absorption and adsorption of the air pump by personal sampler and high volume air samples. The air is sucked through glass fiber filter and a column of 10 ml of carbon tetra chloride in a hubble bubble tube. Results:- Time of exposure is 0-5 years and in most of the cases the forced expiratory volume in one second is 70% + 5 but peak expiratory flow rate is markedly decreased which shows that lung functions are deteriorated to a considerable extent. As the time of exposure increases that is from 6 to 10 years, 11-15 years and 16-20 years, the lung functions steadily decreases by the increase in the time of exposure and extent of deteriorating in lung functions.
Descriptors
glass fiber, ink, absorption, adsorption, adult, air sampling, article, clinical article, cross-sectional study, forced expiratory volume, health hazard, human, lung function, occupational exposure, occupational hazard, printing
Links
Book Title
Database
Embase
Publisher
Data Source
Embase
Authors
Bhatti,A. M., Faridi,I. A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Evaluation of periodontal status in subjects with hyperlipidemia 2010 College of Dentistry at King Saud University in Riyadh, Saudi Arabia. fawartani@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The journal of contemporary dental practice
Periodical, Abbrev.
J.Contemp.Dent.Pract.
Pub Date Free Form
1-Mar
Volume
11
Issue
2
Start Page
33
Other Pages
40
Notes
LR: 20131121; JID: 101090552; 0 (Cholesterol, HDL); 0 (Cholesterol, LDL); 0 (Triglycerides); 97C5T2UQ7J (Cholesterol); epublish
Place of Publication
United States
ISSN/ISBN
1526-3711; 1526-3711
Accession Number
PMID: 20228985
Language
eng
SubFile
Comparative Study; Journal Article; D; IM
DOI
1526-3711-673 [pii]
Output Language
Unknown(0)
PMID
20228985
Abstract
AIM: The aim of this study was to evaluate the periodontal status in subjects with hyperlipidemia and to determine whether there is any association between hyperlipidemia and periodontal disease. METHODS AND MATERIALS: Sixty female patients were enrolled in the study; group one is hyperlipidemic patients (30 subjects) and group 2 is systemically fit patients within the same age group (control; 30 subjects). In both groups body mass index (BMI) and clinical parameters were measured; plaque index (PI), bleeding on probing (BOP), pocket depth (PPD) as well as clinical attachment level (CAL) and biochemical parameters, including plasma triglyceride, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels, were evaluated. RESULTS: The mean values of BMI, PPD, CAL, PI (%), and BOP (%) for the hyperlipidemia group were significantly higher than those for the control group. Total cholesterol and LDL-C levels were significantly and positively associated with CAL. Plasma triglyceride level was significantly associated with PPD and CAL. CONCLUSIONS: The results of our study showed that female patients with hyperlipidemia had higher values of periodontal parameters compared to control individuals. However, in the future studies with larger sample sizes in mixed gender populations are needed to determine the association between hyperlipidemia and periodontal disease. CLINICAL SIGNIFICANCE: The results of our study showed that female patients with hyperlipidemia might manifest clinically higher values of periodontal parameters compared to nonlipdemic individuals. However, due to the small sample size of this study the exact association between hyperlipidemia and periodontal disease is still uncertain. Care has to be taken with a hyperlipidemia patients and advice can be given to them for periodic periodontal checkup.
Descriptors
Adult, Body Mass Index, Case-Control Studies, Cholesterol/blood, Cholesterol, HDL/blood, Cholesterol, LDL/blood, Cross-Sectional Studies, Dental Plaque Index, Female, Gingival Hemorrhage/classification, Humans, Hyperlipidemias/blood/complications, Middle Aged, Periodontal Attachment Loss/classification, Periodontal Diseases/complications, Periodontal Index, Periodontal Pocket/classification, Social Class, Triglycerides/blood
Links
Book Title
Database
Publisher
Data Source
Authors
Awartani,F., Atassi,F.
Original/Translated Title
URL
Date of Electronic
20100301
PMCID
Editors
Evaluation of Scotchbond Multipurpose and maleic acid as alternative methods of bonding orthodontic brackets 1997 Orthodontic Department, Indiana University, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, its Constituent Societies, and the American Board of Orthodontics
Periodical, Abbrev.
Am.J.Orthod.Dentofacial Orthop.
Pub Date Free Form
May
Volume
111
Issue
5
Start Page
498
Other Pages
501
Notes
LR: 20121115; JID: 8610224; 0 (Dentin-Bonding Agents); 0 (Maleates); 0 (Phosphoric Acids); 0 (Resin Cements); 0 (Scotchbond Multi-Purpose); 0 (System 1 plus); 91XW058U2C (maleic acid); ppublish
Place of Publication
UNITED STATES
ISSN/ISBN
0889-5406; 0889-5406
Accession Number
PMID: 9155808
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; D; IM
DOI
S0889-5406(97)70286-5 [pii]
Output Language
Unknown(0)
PMID
9155808
Abstract
Damage to the enamel surface during bonding and debonding of orthodontic brackets is a clinical concern. Alternative bonding methods that minimize enamel surface damage while maintaining a clinically useful bond strength is an aim of current research. The purpose of this study was to compare the effects on bond strength and bracket failure location of two adhesives (System 1+ and Scotchbond Multipurpose, 3M Dental Products Division) and two enamel conditioners (37% phosphoric acid and 10% maleic acid). Forty-eight freshly extracted human premolars were pumiced and divided into four groups of 12 teeth, and metal orthodontic brackets were attached to the enamel surface by one of four protocols: (1) System 1+ and phosphoric acid, (2) Scotchbond and phosphoric acid, (3) System 1+ and maleic acid, and (4) Scotchbond and maleic acid. After bracket attachment, the teeth were mounted in phenolic rings and stored in deionized water at 37 degrees C for 72 hours. A Zwick universal testing machine (Zwick GmbH & Co.) was used to determine shear bond strengths. The residual adhesive on the enamel surface was evaluated with the Adhesive Remnant Index. The analysis of variance was used to compare the four groups. Significance was predetermined at p < or = 0.05. The results indicated that there were no significant differences in bond strength among the four groups (p = 0.386). The results of the Chi square test, evaluating the residual adhesives on the enamel surfaces, revealed significant differences among the four groups (mean 2 = 0.005). A Duncan multiple range test revealed the difference occurred between the phosphoric acid and maleic acid groups, with maleic acid having bond failures at the enamel-adhesive interface. In conclusion, the use of Scotchbond Multipurpose and/or maleic acid does not significantly effect bond strength, however, the use of maleic acid resulted in an unfavorable bond failure location.
Descriptors
Acid Etching, Dental/adverse effects, Analysis of Variance, Bicuspid, Dental Bonding/adverse effects, Dental Debonding/adverse effects, Dental Enamel/injuries/ultrastructure, Dental Stress Analysis/instrumentation, Dentin-Bonding Agents/chemistry, Equipment Failure, Evaluation Studies as Topic, Humans, Maleates/chemistry, Materials Testing/instrumentation, Orthodontic Brackets, Phosphoric Acids/chemistry, Resin Cements/chemistry, Stress, Mechanical, Surface Properties, Tensile Strength
Links
Book Title
Database
Publisher
Data Source
Authors
Olsen,M. E., Bishara,S. E., Damon,P., Jakobsen,J. R.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Evaluation of shear bond strength of orthodontic brackets bonded with Er-YAG laser etching 2012 Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan ; Department of Orthodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Dental research journal
Periodical, Abbrev.
Dent.Res.J.(Isfahan)
Pub Date Free Form
May
Volume
9
Issue
3
Start Page
288
Other Pages
293
Notes
LR: 20130530; JID: 101471186; OID: NLM: PMC3469894; OTO: NOTNLM; ppublish
Place of Publication
Iran
ISSN/ISBN
2008-0255; 1735-3327
Accession Number
PMID: 23087733
Language
eng
SubFile
Journal Article
DOI
Output Language
Unknown(0)
PMID
23087733
Abstract
BACKGROUND: Based on contradictory findings concerning the use of lasers for enamel etching, the purpose of this study was to investigate the shear bond strength of teeth prepared for bonding with Er-YAG laser etching and compare them with phosphoric acid etching. MATERIALS AND METHODS: In this in vitro study forty - eight premolars, extracted for orthodontic purposes were randomly divided in to three groups. Thirty-two teeth were exposed to laser energy for 25 s: 16 teeth at 100 mj setting and 16 teeth at 150 mj setting. Sixteen teeth were etched with 37% phosphoric acid. The shear bond strength of bonded brackets with the Transbond XT adhesive system was measured with the Zwick testing machine. Descriptive statistics, Kolmogorov-Smirnov test, of homogeneity of variances, one- way analysis of variances and Tukey's test and Kruskal Wallis were used to analyze the data. RESULTS: The mean shear bond strength of the teeth lased with 150 mj was 12.26 +/- 4.76 MPa, which was not significantly different from the group with acid etching (15.26 +/- 4.16 MPa). Irradiation with 100 mj resulted in mean bond strengths of 9.05 +/- 3.16 MPa, which was significantly different from that of acid etching (P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Raji,S.H., Birang,R., Majdzade,F., Ghorbanipour,R.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC3469894
Editors
Evaluation of shear bond strength with different enamel pre-treatments 2004 Department of Orthodontics, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
European journal of orthodontics
Periodical, Abbrev.
Eur.J.Orthod.
Pub Date Free Form
Apr
Volume
26
Issue
2
Start Page
179
Other Pages
184
Notes
LR: 20041117; JID: 7909010; 0 (Panavia TPN-S); 0 (Phosphates); 0 (Resin Cements); 0 (Transbond XT); ppublish
Place of Publication
England
ISSN/ISBN
0141-5387; 0141-5387
Accession Number
PMID: 15130041
Language
eng
SubFile
Journal Article; D; IM
DOI
Output Language
Unknown(0)
PMID
15130041
Abstract
The purpose of this study was to investigate the shear bond strengths of two adhesives, Panavia-21 and a composite resin (Transbond XT), with different enamel pre-treatments, acid etching (37 per cent phosphoric acid) and grit blasting (50 microm aluminium oxide particles). The mode of bond failure was also assessed using the modified adhesive remnant index (ARI). Ninety freshly extracted non-carious human premolar teeth were randomly divided into the following groups: (1) Transbond XT, acid-etched enamel surface; (2) Panavia-21, acid-etched enamel surface; (3) Transbond XT, grit-blasted enamel surface; (4) Panavia-21, grit-blasted enamel surface; (5) Transbond XT, acid-etched enamel surface with grit-blasted brackets; (6) Panavia-21, acid-etched enamel surface with grit-blasted brackets. All groups had stainless steel brackets bonded to the buccal surface of each tooth. An Instron universal testing machine was used to determine the shear bond strengths at a crosshead speed of 0.5 mm/second. Statistical analysis was undertaken using analysis of variance and the Tukey test. The mean bond strength values were as follows: group 1, 135.7 +/- 23.0 N; group 2, 181.5 +/- 18.4 N; group 3, 38.4 +/- 27.5 N; group 4, 59.1 +/- 24.1 N; group 5, 106.7 +/- 21.5 N; group 6, 165.3 +/- 21.4 N. Panavia-21 with the acid-etched enamel surface had a significantly higher shear bond strength than the other groups (P < 0.001). This was followed by the composite group with the acid-etched enamel surface. This group differed significantly from the composite and Panavia-21 groups with the grit-blasted tooth surface (P < 0.001) and from the composite and Panavia-21 groups with the acid-etched enamel surface and grit-blasted brackets (P < 0.01). The current findings indicate that Panavia-21 is an excellent adhesive and produces a bond strength that is clinically useful. Enamel surface preparation using grit blasting alone results in a significantly lower bond strength and should not be advocated for clinical use.
Descriptors
Analysis of Variance, Dental Bonding, Dental Enamel, Dental Etching/methods, Dental Stress Analysis, Humans, Materials Testing, Orthodontic Brackets, Phosphates, Random Allocation, Resin Cements, Shear Strength, Surface Properties
Links
Book Title
Database
Publisher
Data Source
Authors
Abu Alhaija,E. S., Al-Wahadni,A. M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Evaluation of Syngonanthus nitens (Bong.) Ruhl. extract as antifungal and in treatment of vulvovaginal candidiasis 2013 * Biological Sciences Department, Faculty of Pharmaceutical Sciences.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Medical mycology
Periodical, Abbrev.
Med.Mycol.
Pub Date Free Form
Oct
Volume
51
Issue
7
Start Page
673
Other Pages
682
Notes
JID: 9815835; 0 (Antifungal Agents); 0 (Flavones); 0 (Ointments); 0 (Plant Extracts); 2013/06/13 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1460-2709; 1369-3786
Accession Number
PMID: 23758104
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.3109/13693786.2013.795294 [doi]
Output Language
Unknown(0)
PMID
23758104
Abstract
The purpose of this study was to evaluate the in vitro anticandidal activity of a methanolic extract of Syngonanthus nitens scapes against different Candida species and clinical isolates from patients with vulvovaginal candidiasis (VVC), and its effect in vivo in the treatment of vaginal infection. Chemical characterization of the extract was performed by HPLC-UV analyses and showed the presence of flavones derivatives. The extract was effective against several Candida strains from our collection and species recovered from VVC patients, and was able to inhibit the yeast-hyphal transition. No cytotoxic activity against human female reproductive tract epithelial cells and no hemolytic activity against human red blood cells were observed. In the in vivo model of VVC, we evaluated the efficacy of the intravaginal treatment with a cream containing the extract at doses of 0.5, 1.0 and 2.0%. The treatment eradicated the vaginal fungal burden in infected rats after 8 days of treatment. S. nitens extract could be considered as an effective and non-toxic natural antifungal agent in the treatment of vulvovaginal candidiasis.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
de Freitas Araujo,M.G., Pacifico,M., Vilegas,W., Dos Santos,L.C., Icely,P.A., Miro,M.S., Scarpa,M.V., Bauab,T.M., Sotomayor,C.E.
Original/Translated Title
URL
Date of Electronic
20130613
PMCID
Editors
Evaluation of the conjunctival fungal flora and its susceptibility to antifungal agents in healthy horses in Switzerland 2014 Equine Department, Section of Ophthalmology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Veterinary ophthalmology
Periodical, Abbrev.
Vet.Ophthalmol.
Pub Date Free Form
Jul
Volume
17 Suppl 1
Issue
Start Page
31
Other Pages
36
Notes
CI: (c) 2013; JID: 100887377; 0 (Antifungal Agents); 304NUG5GF4 (Itraconazole); 7NNO0D7S5M (Miconazole); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); JFU09I87TR (Voriconazole); OTO: NOTNLM; 2013/08/02 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1463-5224; 1463-5216
Accession Number
PMID: 23910390
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1111/vop.12088 [doi]
Output Language
Unknown(0)
PMID
23910390
Abstract
OBJECTIVE: To characterize the conjunctival fungal flora and to determine the susceptibility of 2 isolated molds to antifungal drugs in samples of 64 healthy horses from The National Stud in Switzerland. PROCEDURE: Conjunctival cytobrush samples were collected from both eyes of 64 ophthalmologically normal horses in August 2012 and subsequently cultured on Sabouraud's agar medium. Growing fungi were identified and counted. Etests or broth microdilution tests for Aspergillus fumigatus and Eurotium amstelodami were carried out to determine antifungal drug sensitivity. These species had previously been detected in samples from eyes with keratomycosis in Switzerland. Minimal inhibitory concentrations (MICs) for voriconazole, fluconazole, itraconazole, amphotericin B, and miconazole were recorded. RESULTS: Fifty-nine of the horses were tested positive for fungal growth from at least one eye (92%). Eleven genera of fungi were identified. The most common fungal genera were Alternaria, Eurotium, Rhizopus, and Cladosporium. Aspergillus spp. and Penicillium spp. were isolated frequently, while no Fusarium spp. was found. In only 2 cases, yeasts were identified as Candida guilliermondii. For certain fungal species, the type of bedding and housing appeared to influence their prevalence. Susceptibility testing of A. fumigatus showed lowest MICs for voriconazole, E. amstelodami for voriconazole and itraconazole. High MICs for fluconazole were detected for all tested fungi while MICs for amphotericin B and miconazole were variable. CONCLUSIONS: A large range of fungal mold species was identified including A. fumigatus and E. amstelodami, which have been causative agents of keratomycosis in Switzerland. Best in vitro susceptibility results for these two species were obtained for voriconazole.
Descriptors
Links
Book Title
Database
Publisher
American College of Veterinary Ophthalmologists
Data Source
Authors
Voelter-Ratson,K., Monod,M., Unger,L., Spiess,B.M., Pot,S.A.
Original/Translated Title
URL
Date of Electronic
20130802
PMCID
Editors
Evaluation of the contamination of spirits by polycyclic aromatic hydrocarbons using ultrasound-assisted emulsification microextraction coupled to gas chromatography-mass spectrometry 2016 Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100 Murcia, Spain.; Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of Interna
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Food Chemistry
Periodical, Abbrev.
Food Chem.
Pub Date Free Form
1-Jan
Volume
190
Issue
Start Page
324
Other Pages
330
Notes
CI: Copyright (c) 2015; JID: 7702639; 0 (Emulsions); 0 (Polycyclic Hydrocarbons, Aromatic); 059QF0KO0R (Water); OTO: NOTNLM; 2015/02/08 [received]; 2015/05/25 [revised]; 2015/05/26 [accepted]; 2015/05/27 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
0308-8146; 0308-8146
Accession Number
PMID: 26212977
Language
eng
SubFile
Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.foodchem.2015.05.106 [doi]
Output Language
Unknown(0)
PMID
26212977
Abstract
The concentration of twelve polycyclic aromatic hydrocarbons (PAHs), included in the list of priority pollutants, in different spirits has been obtained by means of a rapid and sensitive method based on gas chromatography and mass spectrometry (GC-MS). The environmentally friendly ultrasound-assisted emulsification microextraction (USAEME) technique allowed the easy and effective preconcentration of the PAHs from the sample matrices. Several parameters affecting the extraction efficiency, such as the nature and volume of the extractant solvent, and the addition of salt, as well as the sonication parameters were investigated and optimized. The absence of matrix effects under the optimized conditions allowed the sample quantification against aqueous standards. Detection limits ranged between 1.8 and 6.3 ng L(-1), depending on the compound. Different spirit samples were successfully analyzed using the proposed method, and contents of up to 0.9 mug L(-1) were found. Relative recoveries at fortified levels of 0.2 and 1 mug L(-1) were in the range 84-118%.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Cacho,J.I., Campillo,N., Vinas,P., Hernandez-Cordoba,M.
Original/Translated Title
URL
Date of Electronic
20150527
PMCID
Editors
Evaluation of the effect of pentoxifylline on sleep-deprivation induced memory impairment 2013 Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Hippocampus
Periodical, Abbrev.
Hippocampus
Pub Date Free Form
Sep
Volume
23
Issue
9
Start Page
812
Other Pages
819
Notes
CI: Copyright (c) 2013; JID: 9108167; 0 (Phosphodiesterase Inhibitors); EC 1.11.1.6 (Catalase); EC 1.11.1.9 (Glutathione Peroxidase); EC 1.15.1.1 (Superoxide Dismutase); GAN16C9B8O (Glutathione); SD6QCT3TSU (Pentoxifylline); OTO: NOTNLM; 2013/04/05 [accep
Place of Publication
United States
ISSN/ISBN
1098-1063; 1050-9631
Accession Number
PMID: 23592546
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1002/hipo.22135 [doi]
Output Language
Unknown(0)
PMID
23592546
Abstract
In this study, we examined the ability of Pentoxifylline (PTX) to prevent sleep deprivation induced memory impairment probably through decreasing oxidative stress. Sleep deprivation was chronically induced 8 h/day for 6 weeks in rats using modified multiple platform model. Concurrently, PTX (100 mg/kg) was administered to animals on daily basis. After 6 weeks of treatment, behavioral studies were conducted to test the spatial learning and memory using the Radial Arm Water Maze. Additionally, the hippocampus was dissected; and levels/activities of antioxidant defense biomarkers glutathione reduced (GSH), glutathione oxidized (GSSG), GSH/GSSG ratio, glutathione peroxidase (GPx), catalase, and superoxide dismutase (SOD), were assessed. The results show that chronic sleep deprivation impaired short- and long-term memories, which was prevented by chronic treatment with PTX. Additionally, PTX normalized sleep deprivation-induced reduction in the hippocampus GSH/GSSG ratio (P
Descriptors
Links
Book Title
Database
Publisher
Wiley Periodicals, Inc
Data Source
Authors
Alzoubi,K.H., Khabour,O.F., Tashtoush,N.H., Al-Azzam,S.I., Mhaidat,N.M.
Original/Translated Title
URL
Date of Electronic
20130522
PMCID
Editors