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The subject of interest is:
waterpipe, water-pipe, nargile, narghile, arguileh, arguile, shisha, sheesha, chichi, hubble bubble, hubbly bubbly, goza, hookah, bong
| Title | Pub Year | Author | SearchLink Sort descending |
|---|---|---|---|
| Adolescents' response to pictorial warnings on the reverse panel of cigarette packs: a repeat cross-sectional study | 2015 | Centre for Tobacco Control Research, Institute for Social Marketing, University of Stirling, Stirling, Stirlingshire, UK.; Centre for Tobacco Control Research, Institute for Social Marketing, University of Stirling, Stirling, Stirlingshire, UK.; Centre fo | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Mar
Volume
24
Issue
e1
Start Page
e93
Other Pages
7
Notes
CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: C312/A8721/Cancer Research UK/United Kingdom; JID: 9209612; OTO
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 24005566
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1136/tobaccocontrol-2013-050999 [doi]
Output Language
Unknown(0)
PMID
24005566
Abstract
BACKGROUND: The UK (UK) became the third country in the European Union to require pictorial warnings on the back of cigarette packs, in October 2008. METHODS: A repeat cross-sectional survey was conducted with 11-16-year-olds in the UK between August and September 2008 (N=1401) and August and September 2011 (N=1373). At both waves the same text warnings appeared on the front and back of packs, with the only difference being the inclusion of images on the back of packs to support the text warnings in 2011. Warning related measures assessed were salience (noticing, looking closely at warnings), depth of processing (thinking about warnings, discussing them with others), comprehension and credibility (warning comprehensibility, believability and truthfulness), unaided recall, persuasiveness (warnings as a deterrent to smoking), avoidance techniques (eg, hiding packs) and a behavioural indicator (forgoing cigarettes due to warnings). RESULTS: For never smokers, warning persuasiveness and thinking about what warnings are telling them when the pack is in sight significantly increased from 2008 to 2011, but warning comprehensibility significantly decreased. For experimental smokers, there was a significant increase from 2008 to 2011 for warning persuasiveness, believing warnings and considering them truthful. For regular smokers, there were no significant changes from 2008 to 2011, except for an increase in hiding packs to avoid warnings and a decrease in warning salience. CONCLUSIONS: Including pictorial images on the back of cigarette packaging improved warning persuasiveness for never and experimental smokers, but had a negligible impact on regular smokers. The findings have implications for warning design.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Moodie,C., Mackintosh,A.M., Hastings,G.
Original/Translated Title
URL
Date of Electronic
20130904
PMCID
Editors
|
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| Diversity and technological potential of lactic acid bacteria of wheat flours | 2013 | Department of Agricultural and Forestry Science, University of Palermo, Palermo, Italy. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Food Microbiology
Periodical, Abbrev.
Food Microbiol.
Pub Date Free Form
Dec
Volume
36
Issue
2
Start Page
343
Other Pages
354
Notes
CI: Copyright (c) 2013; JID: 8601127; 0 (Acids); 0 (Bacterial Proteins); 33X04XA5AT (Lactic Acid); EC 3.4.- (Peptide Hydrolases); OTO: NOTNLM; 2013/01/08 [received]; 2013/06/29 [revised]; 2013/07/09 [accepted]; 2013/07/18 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1095-9998; 0740-0020
Accession Number
PMID: 24010616
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.fm.2013.07.003 [doi]
Output Language
Unknown(0)
PMID
24010616
Abstract
Lactic acid bacteria (LAB) were analysed from wheat flours used in traditional bread making throughout Sicily (southern Italy). Plate counts, carried out in three different media commonly used to detect food and sourdough LAB, revealed a maximal LAB concentration of approximately 4.75 Log CFU g(-1). Colonies representing various morphological appearances were isolated and differentiated based on phenotypic characteristics and genetic analysis by randomly amplified polymorphic DNA (RAPD)-PCR. Fifty unique strains were identified. Analysis by 16S rRNA gene sequencing grouped the strains into 11 LAB species, which belonged to six genera: Enterococcus, Lactobacillus, Lactococcus, Leuconostoc, Pediococcus and Weissella. Weissella cibaria, Lactobacillus plantarum, Leuconostoc pseudomesenteroides and Leuconostoc citreum were the most prevalent species. The strains were not geographically related. Denaturing gradient gel electrophoresis (DGGE) analysis of total DNA of flour was used to provide a more complete understanding of the LAB population; it confirmed the presence of species identified with the culture-dependent approach, but did not reveal the presence of any additional LAB species. Finally, the technological characteristics (acidifying capacity, antimicrobial production, proteolytic activity, organic acid, and volatile organic compound generation) of the 50 LAB strains were investigated. Eleven strains were selected for future in situ applications.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Alfonzo,A., Ventimiglia,G., Corona,O., Di Gerlando,R., Gaglio,R., Francesca,N., Moschetti,G., Settanni,L.
Original/Translated Title
URL
Date of Electronic
20130718
PMCID
Editors
|
|||
| Assessment of coronary artery disease risk in 5463 patients undergoing cardiac surgery: when is preoperative coronary angiography necessary? | 2013 | Division of Cardiovascular Surgery, Mayo Clinic College of Medicine, Rochester, Minn. | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of thoracic and cardiovascular surgery
Periodical, Abbrev.
J.Thorac.Cardiovasc.Surg.
Pub Date Free Form
Nov
Volume
146
Issue
5
Start Page
1055
Other Pages
1063, 1064.e1; discussion 1063-1064
Notes
CI: Copyright (c) 2013; JID: 0376343; OTO: NOTNLM; 2013/05/05 [received]; 2013/06/10 [revised]; 2013/06/26 [accepted]; 2013/09/04 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1097-685X; 0022-5223
Accession Number
PMID: 24012061
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; AIM; IM
DOI
10.1016/j.jtcvs.2013.06.046 [doi]
Output Language
Unknown(0)
PMID
24012061
Abstract
OBJECTIVES: We sought to critically analyze the routine use of conventional coronary angiography (CCA) before noncoronary cardiac surgery and to assess clinical prediction models that might allow more selective use of CCA in this setting. METHODS: We studied 5463 patients undergoing aortic valve surgery, mitral valve surgery, or septal myectomy with or without coronary artery bypass grafting from 2001 to 2010. Preoperative CCAs were evaluated for the presence of significant coronary artery disease (CAD). Random forests and logistic regression methods were used to determine the predictors of significant (>/=50%) coronary stenosis. RESULTS: Preoperative CCA was performed in 4711 patients (86%). Two thirds of those with angina, previous myocardial infarction, or percutaneous coronary intervention had significant CAD found on CCA, versus one third of patients free of these risk factors (P
Descriptors
Links
Book Title
Database
Publisher
The American Association for Thoracic Surgery. Published by Mosby, Inc
Data Source
Authors
Thalji,N.M., Suri,R.M., Daly,R.C., Dearani,J.A., Burkhart,H.M., Park,S.J., Greason,K.L., Joyce,L.D., Stulak,J.M., Huebner,M., Li,Z., Frye,R.L., Schaff,H.V.
Original/Translated Title
URL
Date of Electronic
20130904
PMCID
Editors
|
|||
| Extended interactive voice response telephony (IVR) for relapse prevention after smoking cessation using varenicline and IVR: a pilot study | 2013 | Healthy Heart Program, Providence Health Care, St, Paul's Hospital, 1081 Burrard Street, Vancouver B,C, V6Z 1Y6, Canada. bmcnaughton@providencehealth.bc.ca. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
10-Sep
Volume
13
Issue
Start Page
824
Other Pages
2458-13-824
Notes
LR: 20151119; ClinicalTrials.gov/NCT00832806; JID: 100968562; 0 (Benzazepines); 0 (Nicotinic Agonists); 0 (Quinoxalines); W6HS99O8ZO (Varenicline); OID: NLM: PMC3848019; 2013/05/06 [received]; 2013/08/30 [accepted]; 2013/09/10 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 24020450
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2458-13-824 [doi]
Output Language
Unknown(0)
PMID
24020450
Abstract
BACKGROUND: There is a significant resumption of smoking following smoking cessation using varenicline. Both smoking cessation medications and counseling have been shown to increase smoking quit rates at one year. Thus, the combination of varenicline and interactive voice response (IVR) telephony followed by extended IVR may further improve smoking cessation rates at one and two years. METHODS: 101 participants were recruited from the community via newspaper advertisement. They attended a group counseling session and were given smoking information booklets from the Canadian Cancer Society. After 12 weeks of varenicline and 9 IVR calls, all participants who had quit smoking were randomized into 2 groups matched by levels of motivation and addiction as per baseline questionnaire score. The intervention group continued to receive bi-weekly IVR support for weeks 13-52. The control group no longer received IVR. The primary end-point was self-reported abstinence and exhaled carbon monoxide levels of less than 10 ppm for weeks 12, 52 and 2 years. Data were analyzed by Fisher's exact test or Wilcoxon rank-sum test. RESULTS: Of the 101 participants, 44 (43%) had stopped smoking after 12 weeks of varenicline and 9 IVR calls. Of these, 23 (52%) were randomized to receive IVR calls from weeks 13 to 52.At 52 weeks, 26 (59%) participants remained smoke-free. Of the 23 with IVR, 12 (52.2%) stopped smoking compared to 14 of 21 (66.7%) without IVR. At 2 years, 40 of the 44 (90.9%) randomized participants were contacted and 24 of the 44 (54.5%) came in for testing. Fourteen (13% of the original cohort, 30% who were abstinent at 12 weeks and 53% who were abstinent at 52 weeks) remained smoke-free. Five of the 23 (21.7%) randomized to IVR and 9 of the 21 (42.9%) randomized to no IVR remained smoke-free at 2 years. CONCLUSIONS: In this pilot study of an apparently healthy population, extended IVR did not affect abstinence rates. There was no relapse prevention benefit in offering 9 months of continued IVR to subjects who had stopped smoking after receiving 3 months of varenicline and IVR treatment. TRIAL REGISTRATION: ClinicalTrial.gov: NCT00832806.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
McNaughton,B., Frohlich,J., Graham,A., Young,Q.R.
Original/Translated Title
URL
Date of Electronic
20130910
PMCID
PMC3848019
Editors
|
|||
| Two men with multiple disabilities carry out an assembly work activity with the support of a technology system | 2013 | Department of Neuroscience and Sense Organs, University of Bari , 70100 Bari , Italy. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Developmental neurorehabilitation
Periodical, Abbrev.
Dev.Neurorehabil
Pub Date Free Form
Oct
Volume
16
Issue
5
Start Page
332
Other Pages
339
Notes
LR: 20151119; JID: 101304394; ppublish
Place of Publication
England
ISSN/ISBN
1751-8431; 1751-8423
Accession Number
PMID: 24020878
Language
eng
SubFile
Case Reports; Journal Article; IM
DOI
10.3310/phr04020 [doi]
Output Language
Unknown(0)
PMID
24020878
Abstract
OBJECTIVE: To assess whether two persons with multiple disabilities could learn a work activity (i.e., assembling trolley wheels) with the support of a technology system. METHOD: After an initial baseline, the study compared the effects of intervention sessions relying on the technology system (which called the participants to the different workstations and provided feedback and final stimulation) with the effects of intervention sessions carried out without technology. The two types of intervention sessions were conducted according to an alternating treatments design. Eventually, only intervention sessions relying on the technology system were used. RESULTS: Both participants managed to assemble wheels independently during intervention sessions relying on the technology system while they failed during sessions without the system. Their performance was strengthened during the final part of the study, in which only sessions with the system occurred. CONCLUSION: Technology may be critical in helping persons with multiple disabilities manage multi-step work activities.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Lancioni,G.E., Singh,N.N., O'Reilly,M.F., Green,V.A., Oliva,D., Campodonico,F.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
|
|||
| In vitro effectiveness of anidulafungin against Candida sp. biofilms | 2013 | Dipartimento di Farmacia-Scienze del Farmaco, Universita degli Studi di Bari 'Aldo Moro', Via Orabona 4, Bari Italy.; Scuola di Dottorato e Scienze Biomediche e Oncologia umana, Sezione di Igiene, Universita di Bari 'Aldo Moro', Bari, Italy.; Scuola di Do | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of antibiotics
Periodical, Abbrev.
J.Antibiot.(Tokyo)
Pub Date Free Form
Dec
Volume
66
Issue
12
Start Page
701
Other Pages
704
Notes
JID: 0151115; 0 (Antifungal Agents); 0 (Echinocandins); 9HLM53094I (anidulafungin); 2013/03/05 [received]; 2013/05/28 [revised]; 2013/07/30 [accepted]; 2013/09/11 [aheadofprint]; ppublish
Place of Publication
Japan
ISSN/ISBN
0021-8820; 0021-8820
Accession Number
PMID: 24022607
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1038/ja.2013.83 [doi]
Output Language
Unknown(0)
PMID
24022607
Abstract
This study furnishes deeper insights to previous works on anidulafungin, demonstrating the potent activity against Candida strains planktonic cells and biofilms. Candida sp., associated with many biomaterial-related infections, give rise to infective pathologies typically associated with biofilm formation. We recently determined the in vitro antifungal activities of echinocandin anidulafungin in association with some antifungal drugs against some Candida strains in their planktonic states. A total of 11 Candida strains biofilms were tested in this study: six Candida albicans, three C. parapsilosis and two C. tropicalis. All yeast isolates and ATCC strains were stored at -20 degrees C in glycerol stocks and were subcultured on antimicrobial agent-free Sabouraud dextrose agar plates. MIC endpoints were determined colorimetrically by using the indicator 2,3-bis(2-methoxy-4-nitro-5-sulphophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazoliu m hydroxide (XTT) with menadione as electron-coupling agent. The activity of anidulafungin was assessed using in vitro microbiological model relevant for clinical practice. Anidulafungin showed a strong activity in vitro against both planktonic and biofilms cells, and our study confirms that high anidulafungin concentrations might establish paradoxical growth effect in C. albicans and C. tropicalis biofilms.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Rosato,A., Piarulli,M., Schiavone,B.P., Catalano,A., Carocci,A., Carrieri,A., Carone,A., Caggiano,G., Franchini,C., Corbo,F., Montagna,M.T.
Original/Translated Title
URL
Date of Electronic
20130911
PMCID
Editors
|
|||
| Ashtrays and signage as determinants of a smoke-free legislation's success | 2013 | Center for Global Tobacco Control, Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts, United States of America ; Smoking and Lung Cancer Research Center, Hellenic Cancer Society, Athens, Greece ; Clinic o | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
4-Sep
Volume
8
Issue
9
Start Page
e72945
Other Pages
Notes
LR: 20150422; JID: 101285081; OID: NLM: PMC3762932; 2013 [ecollection]; 2013/01/15 [received]; 2013/07/21 [accepted]; 2013/09/04 [epublish]; epublish
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 24023795
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1371/journal.pone.0072945 [doi]
Output Language
Unknown(0)
PMID
24023795
Abstract
INTRODUCTION: Successful smoke-free legislation is dependent on political will, enforcement and societal support. We report the success and pitfalls of a non-enforced nationwide smoke-free legislation in Greece, as well as ways in which compliance and enforcement-related factors, including ashtrays and signage, may impact indoor secondhand smoke (SHS) concentrations. METHODS: A follow-up study of venues (n=150, at baseline, n=75 at 2-year follow-up) in Greece assessed indoor particulate matter with a diameter less than 2.5 micrometers (PM 2.5 ) concentrations attributable to SHS smoke every six months for two years (n=455 venue/measurements). RESULTS: Following the implementation of the 2010 smoke-free legislation, mean PM2.5 concentrations attributable to SHS fell from 175.3 microg/m(3) pre-ban to 84.52 microg/m(3) immediately post-ban, increasing over subsequent waves (103.8 microg/m(3) and 158.2 microg/m(3) respectively). Controlling for potential influential factors such as ventilation, time of day, day of week, city and venue type, all post-ban measurements were still lower than during the pre-ban period (Wave 2 beta: -118.7, Wave 3 beta: -87.6, and Wave 4 beta: -69.9). Outdoor or indoor signage banning smoking was not found to affect SHS concentrations (beta: -10.9, p=0.667 and beta: -18.1, p=0.464 respectively). However, ashtray or ashtray equivalents were strong determinants of the existence of indoor SHS (beta: +67 microg/m(3), p=0.017). CONCLUSIONS: While the public may be supportive of smoke-free legislation, adherence may decline rapidly if enforcement is limited or nonexistent. Moreover, enforcement agencies should also focus on the comprehensive removal of ashtray equivalents that could act as cues for smoking within a venue.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Vardavas,C.I., Agaku,I., Patelarou,E., Anagnostopoulos,N., Nakou,C., Dramba,V., Giourgouli,G., Argyropoulou,P., Antoniadis,A., Gourgoulianis,K., Ourda,D., Lazuras,L., Bertic,M., Lionis,C., Connolly,G., Behrakis,P., Hellenic Air Monitoring Study Investigators
Original/Translated Title
URL
Date of Electronic
20130904
PMCID
PMC3762932
Editors
|
|||
| Effect of environmental factors and fishing effort allocation on catch of the Spotted Eagle Ray Aetobatus narinari (Rajiformes: Myliobatidae) in Southern Gulf of Mexico | 2013 | Departamento de Aprovechamiento y Manejo de Recursos Acuaticos, El Colegio de la Frontera Sur (ECOSUR), Av. Rancho Poligono 2-A, Ciudad Industrial, Lerma, Campeche, Mexico, C.P. 24500. ocelycz@gmail.com | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Revista de biologia tropical
Periodical, Abbrev.
Rev.Biol.Trop.
Pub Date Free Form
Sep
Volume
61
Issue
3
Start Page
1341
Other Pages
1349
Notes
JID: 0404267; ppublish
Place of Publication
Costa Rica
ISSN/ISBN
0034-7744; 0034-7744
Accession Number
PMID: 24027927
Language
spa
SubFile
English Abstract; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
24027927
Abstract
Aetobatus narinari represents a fisheries target in Southern Gulf of Mexico, and it is currently considered a Near Threatened species by the IUCN red list. The information available of this batoid fish includes some biological and fishery aspects; nevertheless, little is known about the factors influencing on fishing operations and catches. In order to evaluate the effect of environmental factors and the fishing effort allocation by vessels on the target fishery of A. narinari in this area, a daily basis sampling was carried out on four small-scale vessels, from January to July 2009 (the entire fishing season), in two fishing localities (Campeche and Seybaplaya). A total of 896 rays were recorded from 280 fishing trips. A General Linear Model was used to predict the factors effect on the probability that fishing operations occurred, and on the probability for captures of at least one or three or five rays per vessel-trip. The probability that fishing operations occurred off Campeche was predicted by the lunar cycle, with the highest probability in the new moon period (66%) and a probability smaller than 35% for the other periods. The probability that fishing operations occurred off Seybaplaya was predicted by wind velocity, with higher probabilities at low wind velocity than at high wind velocity, and a 50% probability of fishing operations at 12-15 km/h. Catch rates off Seybaplaya were predicted by the vessel's factor (the effect of fishing effort allocation), the North wind season and sea surface temperature. The probability for captures of at least one and three rays per vessel-trip was predicted by the vessel's factor and the North wind season. One vessel had higher catch probability (83% for at least one ray and 43% for at least three rays) than the others (69 and 70% for at least one ray and 26% for at least three rays), and during the North wind season the catch probability was higher (96% for at least one ray and 72% for at least three rays) than out of that season (68% for at least one ray and 21% for at least three rays). The probability for capture at least five rays per vessel-trip was predicted by the sea surface temperature and the North wind season. At 23 degrees C the catch probability was of 49% and the probability gradually diminished to 4% at 28 degrees C, and during the North wind season the catch probability was higher (40%) than out of that season (7%). This study shows that some environmental factors and fishermen perceptions and experience (fishing effort allocation) influence on the catch rate of A. narinari, and that these factors must be considered in future studies on elasmobranch fisheries, mainly when comparisons between catch rates among seasons or regions are analyzed.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Cuevas,E., Perez,J.C., Mendez,I.
Original/Translated Title
Efecto de factores ambientales y la asignacion del esfuerzo pesquero sobre las capturas de la raya Aetobatus narinari (Rajiformes: Myliobatidae) en el sur del Golfo de Mexico
URL
Date of Electronic
PMCID
Editors
|
|||
| Dissemination and characterization of plasmids carrying oqxAB-bla CTX-M genes in Escherichia coli isolates from food-producing animals | 2013 | College of Veterinary Medicine, National Reference Laboratory of Veterinary Drug Residues (SCAU), South China Agricultural University, Guangzhou, Guangdong, China. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
9-Sep
Volume
8
Issue
9
Start Page
e73947
Other Pages
Notes
LR: 20150422; JID: 101285081; 0 (Anti-Bacterial Agents); 0 (Quinolones); EC 3.5.2.6 (beta-Lactamases); OID: NLM: PMC3767592; 2013 [ecollection]; 2013/04/28 [received]; 2013/07/24 [accepted]; 2013/09/09 [epublish]; epublish
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 24040123
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1371/journal.pone.0073947 [doi]
Output Language
Unknown(0)
PMID
24040123
Abstract
BACKGROUND: The association of PMQR and ESBLs in negative-bacteria isolates has been of great concern. The present study was performed to investigate the prevalence of co-transferability of oqxAB and bla CTX-M genes among the 696 Escherichia coli (E. coli) isolates from food-producing animals in South China, and to characterize these plasmids. METHODS: The ESBL-encoding genes (bla(CTX-M), bla(TEM) and bla(SHV)), and PMQR (qnrA, qnrB, qnrS, qnrC, qnrD, aac(6')-Ib-cr, qepA, and oqxAB) of these 696 isolates were determined by PCR and sequenced directionally. Conjugation, S1 nuclease pulsed-field gel electrophoresis (PFGE) and Southern blotting experiments were performed to investigate the co-transferability and location of oqxAB and bla(CTX-M). The EcoRI digestion profiles of the plasmids with oqxAB-bla(CTX-M) were also analyzed. The clonal relatedness was investigated by PFGE. RESULTS: Of the 696 isolates, 429 harbored at least one PMQR gene, with oqxAB (328) being the most common type; 191 carried bla(CTX-M), with bla(CTX-M-14) the most common. We observed a significant higher prevalence of bla(CTX-M) among the oqxAB-positive isolates (38.7%) than that (17.4%) in the oqxAB-negative isolates. Co-transferability of oqxAB and bla(CTX-M) was found in 18 of the 127 isolates carrying oqxAB-bla(CTX-M). These two genes were located on the same plasmid in all the 18 isolates, with floR being on these plasmids in 13 isolates. The co-dissemination of these genes was mainly mediated by F33:A-: B- and HI2 plasmids with highly similar EcoRI digestion profiles. Diverse PFGE patterns indicated the high prevalence of oqxAB was not caused by clonal dissemination. CONCLUSION: bla(CTX-M) was highly prevalent among the oqxAB-positive isolates. The co-dissemination of oqxAB-bla(CTX-M) genes in E. coli isolates from food-producing animals is mediated mainly by similar F33:A-: B- and HI2 plasmids. This is the first report of the co-existence of oqxAB, bla(CTX-M), and floR on the same plasmids in E. coli.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Liu,B.T., Yang,Q.E., Li,L., Sun,J., Liao,X.P., Fang,L.X., Yang,S.S., Deng,H., Liu,Y.H.
Original/Translated Title
URL
Date of Electronic
20130909
PMCID
PMC3767592
Editors
|
|||
| Effects of a Web-based tailored intervention to reduce alcohol consumption in adults: randomized controlled trial | 2013 | CAPHRI School for Public Health and Primary Care, Department of Health Promotion, Maastricht University, Maastricht, Netherlands. dn.schulz@maastrichtuniversity.nl | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of medical Internet research
Periodical, Abbrev.
J.Med.Internet Res.
Pub Date Free Form
17-Sep
Volume
15
Issue
9
Start Page
e206
Other Pages
Notes
LR: 20150422; ISRCTN/ISRCTN91623132; JID: 100959882; OID: NLM: PMC3785997; OTO: NOTNLM; 2013/02/06 [received]; 2013/07/01 [accepted]; 2013/05/30 [revised]; epublish
Place of Publication
Canada
ISSN/ISBN
1438-8871; 1438-8871
Accession Number
PMID: 24045005
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM
DOI
10.2196/jmir.2568 [doi]
Output Language
Unknown(0)
PMID
24045005
Abstract
BACKGROUND: Web-based tailored interventions provide users with information that is adapted to their individual characteristics and needs. Randomized controlled trials assessing the effects of tailored alcohol self-help programs among adults are scarce. Furthermore, it is a challenge to develop programs that can hold respondents' attention in online interventions. OBJECTIVE: To assess whether a 3-session, Web-based tailored intervention is effective in reducing alcohol intake in high-risk adult drinkers and to compare 2 computer-tailoring feedback strategies (alternating vs summative) on behavioral change, dropout, and appreciation of the program. METHODS: A single-blind randomized controlled trial was conducted with an experimental group and a control group (N=448) in Germany in 2010-2011. Follow-up took place after 6 months. Drinking behavior, health status, motivational determinants, and demographics were assessed among participants recruited via an online access panel. The experimental group was divided into 2 subgroups. In the alternating condition (n=132), the tailored feedback was split into a series of messages discussing individual topics offered while the respondent was filling out the program. Participants in the summative condition (n=181) received all advice at once after having answered all questions. The actual texts were identical for both conditions. The control group (n=135) only filled in 3 questionnaires. To identify intervention effects, logistic and linear regression analyses were conducted among complete cases (n=197) and after using multiple imputation. RESULTS: Among the complete cases (response rate: 197/448, 44.0%) who did not comply with the German national guideline for low-risk drinking at baseline, 21.1% of respondents in the experimental group complied after 6 months compared with 5.8% in the control group (effect size=0.42; OR 2.65, 95% CI 1.14-6.16, P=.02). The experimental group decreased by 3.9 drinks per week compared to 0.4 drinks per week in the control group, but this did not reach statistical significance (effect size=0.26; beta=-0.12, 95% CI -7.96 to 0.03, P=.05). Intention-to-treat analyses also indicated no statistically significant effect. Separate analyses of the 2 experimental subgroups showed no differences in intervention effects. The dropout rate during the first visit to the intervention website was significantly lower in the alternating condition than in the summative condition (OR 0.23, 95% CI 0.08-0.60, P=.003). Program appreciation was comparable for the 2 experimental groups. CONCLUSIONS: Complete case analyses revealed that Web-based tailored feedback can be an effective way to reduce alcohol intake among adults. However, this effect was not confirmed when applying multiple imputations. There was no indication that one of the tailoring strategies was more effective in lowering alcohol intake. Nevertheless, the lower attrition rates we found during the first visit suggest that the version of the intervention with alternating questions and advice may be preferred. TRIAL REGISTRATION: International Standard Randomized Controlled Trial Number (ISRCTN): 91623132; http://www.controlled-trials.com/ISRCTN91623132 (Archived by WebCite at http://www.webcitation.org/6J4QdhXeG).
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Schulz,D.N., Candel,M.J., Kremers,S.P., Reinwand,D.A., Jander,A., de Vries,H.
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20130917
PMCID
PMC3785997
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