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Adiponectin May Modify the Risk of Barrett's Esophagus in Patients With Gastroesophageal Reflux Disease 2015 Division of Research, Kaiser Permanente, Oakland, California.; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California; Department of Nutrition, University of California, Davis, California.; Departme
Source Type
Print(0)
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Journal Article
Periodical, Full
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Periodical, Abbrev.
Clin.Gastroenterol.Hepatol.
Pub Date Free Form
Dec
Volume
13
Issue
13
Start Page
2256
Other Pages
64.e1-3
Notes
LR: 20151123; CI: Copyright (c) 2015; GR: R01 DK063616/DK/NIDDK NIH HHS/United States; GR: R01 DK63616/DK/NIDDK NIH HHS/United States; GR: R56 DK087748/DK/NIDDK NIH HHS/United States; GR: R56 DK087748/DK/NIDDK NIH HHS/United States; JID: 101160775; 0 (Adi
Place of Publication
United States
ISSN/ISBN
1542-7714; 1542-3565
Accession Number
PMID: 25632808
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.cgh.2015.01.009 [doi]
Output Language
Unknown(0)
PMID
25632808
Abstract
BACKGROUND & AIMS: Abdominal obesity and increasing body mass index are risk factors for esophageal adenocarcinoma and its main precursor, Barrett's esophagus; however, there are no known biological mechanisms for these associations or regarding why only some patients with gastroesophageal reflux disease develop Barrett's esophagus. We evaluated the association between Barrett's esophagus and multimers of an adipose-associated hormone, adiponectin. METHODS: We conducted a case-control study evaluating the associations between adiponectin (total, high-molecular-weight, and low-/medium-molecular-weight) and Barrett's esophagus within the Kaiser Permanente Northern California population. Patients with a new diagnosis of Barrett's esophagus (cases) were matched to patients with gastroesophageal reflux disease (GERD) without Barrett's esophagus and to population controls. RESULTS: Complete serologic and epidemiologic data were available for 284 cases, 294 GERD controls, and 285 population controls. Increasing adiponectin levels were a risk factor for Barrett's esophagus among patients with GERD (total adiponectin fourth vs first quartile odds ratio [OR], 1.96; 95% confidence interval [CI], 1.17-3.27; high-molecular-weight adiponectin OR, 1.65; 95% CI, 1.00-2.73; low-/medium-molecular-weight adiponectin OR, 2.18; 95% CI, 1.33-3.56), but not compared with population controls. The associations were significantly stronger among patients reporting frequent GERD symptoms and among smokers (P values interaction
Descriptors
Links
Book Title
Database
Publisher
AGA Institute. Published by Elsevier Inc
Data Source
Authors
Almers,L.M., Graham,J.E., Havel,P.J., Corley,D.A.
Original/Translated Title
URL
Date of Electronic
20150126
PMCID
PMC4515407
Editors
Puffing topography and nicotine intake of electronic cigarette users 2015 Cell Molecular and Developmental Biology Graduate Program, University of California Riverside, Riverside, California, United States of America; Department of Cell Biology and Neuroscience, University of California Riverside, Riverside, California, United
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
9-Feb
Volume
10
Issue
2
Start Page
e0117222
Other Pages
Notes
LR: 20150219; GR: F32HL116121/HL/NHLBI NIH HHS/United States; JID: 101285081; 6M3C89ZY6R (Nicotine); OID: NLM: PMC4321841; 2015 [ecollection]; 2014/09/05 [received]; 2014/12/20 [accepted]; 2015/02/09 [epublish]; epublish
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 25664463
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1371/journal.pone.0117222 [doi]
Output Language
Unknown(0)
PMID
25664463
Abstract
BACKGROUND: Prior electronic cigarette (EC) topography data are based on two video analyses with limited parameters. Alternate methods for measuring topography are needed to understand EC use and nicotine intake. OBJECTIVES: This study evaluated EC topography with a CReSS Pocket device and quantified nicotine intake. METHODS: Validation tests on pressure drop, flow rate, and volume confirmed reliable performance of the CReSS Pocket device. Twenty participants used Blu Cigs and V2 Cigs for 10 minute intervals with a 10-15 minute break between brands. Brand order was reversed and repeated within 7 days Data were analyzed to determine puff duration, puff count, volume, flow rate, peak flow, and inter-puff interval. Nicotine intake was estimated from cartomizer fluid consumption and topography data. RESULTS: Nine patterns of EC use were identified. The average puff count and inter-puff interval were 32 puffs and 17.9 seconds. All participants, except one, took more than 20 puffs/10 minutes. The averages for puff duration (2.65 seconds/puff), volume/puff (51 ml/puff), total puff volume (1,579 ml), EC fluid consumption (79.6 mg), flow rate (20 ml/s), and peak flow rate (27 ml/s) were determined for 10-minute sessions. All parameters except total puff count were significantly different for Blu versus V2 EC. Total volume for Blu versus V2 was four-times higher than for conventional cigarettes. Average nicotine intake for Blu and V2 across both sessions was 1.2 +/- 0.5 mg and 1.4 +/- 0.7 mg, respectively, which is similar to conventional smokers. CONCLUSIONS: EC puffing topography was variable among participants in the study, but often similar within an individual between brands or days. Puff duration, inter-puff interval, and puff volume varied from conventional cigarette standards. Data on total puff volume and nicotine intake are consistent with compensatory usage of EC. These data can contribute to the development of a standard protocol for laboratory testing of EC products.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Behar,R.Z., Hua,M., Talbot,P.
Original/Translated Title
URL
Date of Electronic
20150209
PMCID
PMC4321841
Editors
Explaining the effects of electronic cigarettes on craving for tobacco in recent quitters 2015 Institute of Global Health, Faculty of Medicine, University of Geneva, CH-1211 Geneva 4, Switzerland. Electronic address: Jean-Francois.Etter@unige.ch.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Drug and alcohol dependence
Periodical, Abbrev.
Drug Alcohol Depend.
Pub Date Free Form
1-Mar
Volume
148
Issue
Start Page
102
Other Pages
108
Notes
CI: Copyright (c) 2015; JID: 7513587; 6M3C89ZY6R (Nicotine); OTO: NOTNLM; 2014/10/23 [received]; 2014/12/17 [revised]; 2014/12/20 [accepted]; 2015/01/03 [aheadofprint]; ppublish
Place of Publication
Ireland
ISSN/ISBN
1879-0046; 0376-8716
Accession Number
PMID: 25592454
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.drugalcdep.2014.12.030 [doi]
Output Language
Unknown(0)
PMID
25592454
Abstract
OBJECTIVE: To explore how e-cigarettes attenuate craving for tobacco, in e-cigarette users who recently quit smoking. DESIGN: Cross-sectional survey of recent quitters, Internet (French and English), 2012-2014. Participants were 374 daily users of e-cigarettes who had quit smoking in the previous two months, enrolled on websites dedicated to e-cigarettes and to smoking cessation. We measured perception that e-cigarettes attenuate craving for tobacco cigarettes, characteristics of e-cigarettes, modifications of the devices, patterns of e-cigarette use, reasons for use, satisfaction with e-cigarettes, dependence on e-cigarettes, and personal characteristics. RESULTS: The strongest attenuation of craving for tobacco was obtained by using higher nicotine concentrations in refill liquids, modular systems (rather than unmodified devices), and high voltage batteries. The strength of the effect of e-cigarettes on craving was also associated with more intensive use (more puffs per day, more refill liquid). Stronger effects on craving were associated with satisfaction with e-cigarettes, and with reporting that e-cigarettes helped to quit smoking. Participants who reported the strongest effects on craving for tobacco were the most dependent on the e-cigarette and had the strongest urges to vape. CONCLUSIONS: From a public health perspective, there is a trade-off between e-cigarettes that provide high levels of nicotine, high satisfaction and more effects on craving for tobacco, but may also be addictive, and e-cigarettes that contain less nicotine and are less addictive, but are also less satisfactory and less efficient at relieving craving and at helping dependent smokers quit smoking. This trade-off must be kept in mind when regulating e-cigarettes.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ireland Ltd
Data Source
Authors
Etter,J.F.
Original/Translated Title
URL
Date of Electronic
20150103
PMCID
Editors
Preliminary results of an examination of electronic cigarette user puff topography: the effect of a mouthpiece-based topography measurement device on plasma nicotine and subjective effects 2015 Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA;; Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA;; Center for the Study
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
17
Issue
2
Start Page
142
Other Pages
149
Notes
LR: 20160519; CI: (c) The Author 2014; GR: P50 DA036105/DA/NIDA NIH HHS/United States; GR: P50DA036105/DA/NIDA NIH HHS/United States; JID: 9815751; 6M3C89ZY6R (Nicotine); OID: NLM: PMC4838000; 2014/09/19 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25239957
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1093/ntr/ntu186 [doi]
Output Language
Unknown(0)
PMID
25239957
Abstract
INTRODUCTION: Electronic cigarettes (ECIGs) heat a nicotine-containing solution; the resulting aerosol is inhaled by the user. Nicotine delivery may be affected by users' puffing behavior (puff topography), and little is known about the puff topography of ECIG users. Puff topography can be measured using mouthpiece-based computerized systems. However, the extent to which a mouthpiece influences nicotine delivery and subjective effects in ECIG users is unknown. METHODS: Plasma nicotine concentration, heart rate, and subjective effects were measured in 13 experienced ECIG users who used their preferred ECIG and liquid (>/= 12 mg/ml nicotine) during 2 sessions (with or without a mouthpiece). In both sessions, participants completed an ECIG use session in which they were instructed to take 10 puffs with 30-second inter-puff intervals. Puff topography was recorded in the mouthpiece condition. RESULTS: Almost all measures of the effects of ECIG use were independent of topography measurement. Collapsed across session, mean plasma nicotine concentration increased by 16.8 ng/ml, and mean heart rate increased by 8.5 bpm (ps
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Spindle,T.R., Breland,A.B., Karaoghlanian,N.V., Shihadeh,A.L., Eissenberg,T.
Original/Translated Title
URL
Date of Electronic
20140919
PMCID
PMC4838000
Editors
Prevalence and correlates of electronic cigarette use among adolescents in Greece: a preliminary cross-sectional analysis of nationwide survey data 2015 National & Kapodistrian University of Athens, Medical School, Department of Neurology-Psychiatry-Social Medicine, 72 Vasilissis Sofias Ave., Athens 11528, Greece; University Mental Health Research Institute, 2 Soranou tou Efesiou St., Athens 11527, Greece
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
Dec
Volume
51
Issue
Start Page
88
Other Pages
92
Notes
CI: Copyright (c) 2015; JID: 7603486; OTO: NOTNLM; 2015/01/11 [received]; 2015/07/21 [revised]; 2015/07/23 [accepted]; 2015/07/26 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1873-6327; 0306-4603
Accession Number
PMID: 26240943
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.addbeh.2015.07.021 [doi]
Output Language
Unknown(0)
PMID
26240943
Abstract
INTRODUCTION: This study reports the prevalence of electronic cigarette (e-cigarette) use among adolescents in Greece and explores how dual smokers of e-cigarettes and combustible (conventional) cigarettes differ from smokers of only combustible cigarettes across socio-demographic, familial, psychosomatic health and substance use characteristics. METHODS: Self-reports on smoking were collected from a nationally representative sample of 1320 15-year-old Greek students in the 2014 Health Behaviour in School-aged Children study. Bivariate and multivariable logistic regression analyses were carried out with dependent variables a) lifetime smoking conventional cigarettes and b) lifetime e-cigarette use among lifetime smokers. RESULTS: About 36.9% of 15-year-olds reported lifetime smoking of conventional cigarettes, and 16.6% lifetime use of e-cigarettes, mostly experimenting (0.5% reported current e-cigarette use). Six in 7 ever e-cigarette smokers had smoked conventional cigarettes. Peers who smoke and lifetime cannabis use were significant correlates of both lifetime conventional cigarette and e-cigarette smoking, but more strongly for smoking conventional cigarettes. Alcohol use and low parental monitoring correlated with tobacco smoking but not e-cigarette use. Girls were more likely than boys to report lifetime use of tobacco, but, among lifetime smokers, boys had almost seven times the odds of girls of e-cigarette use. In lifetime smokers, low life satisfaction in females and current smoking of conventional tobacco were independently associated with the experimentation with e-cigarettes. CONCLUSIONS: Experimental use of e-cigarettes is relatively widespread among adolescents in Greece. Targeted interventions should focus on male smokers and the role of peer processes and cannabis use in the risk of experimenting with e-cigarettes.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Fotiou,A., Kanavou,E., Stavrou,M., Richardson,C., Kokkevi,A.
Original/Translated Title
URL
Date of Electronic
20150726
PMCID
Editors
Clinical features of patients isolated for suspected Ebola virus disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study 2015 King's Sierra Leone Health Partnership, King's Centre for Global Health, King's Health Partners and King's College London, London, UK. Electronic address: marta.lado@kcl.ac.uk.; King's Sierra Leone Health Partnership, King's Centre for Global Health, King
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Lancet.Infectious diseases
Periodical, Abbrev.
Lancet Infect.Dis.
Pub Date Free Form
Sep
Volume
15
Issue
9
Start Page
1024
Other Pages
1033
Notes
LR: 20160713; CI: Copyright (c) 2015; GR: 100693/Wellcome Trust/United Kingdom; GR: Wellcome Trust/United Kingdom; JID: 101130150; CIN: Lancet Infect Dis. 2016 Jan;16(1):18-9. PMID: 26738827; CIN: Lancet Infect Dis. 2015 Sep;15(9):989-90. PMID: 26213247;
Place of Publication
United States
ISSN/ISBN
1474-4457; 1473-3099
Accession Number
PMID: 26213248
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/S1473-3099(15)00137-1 [doi]
Output Language
Unknown(0)
PMID
26213248
Abstract
BACKGROUND: The size of the west African Ebola virus disease outbreak led to the urgent establishment of Ebola holding unit facilities for isolation and diagnostic testing of patients with suspected Ebola virus disease. Following the onset of the outbreak in Sierra Leone, patients presenting to Connaught Hospital in Freetown were screened for suspected Ebola virus disease on arrival and, if necessary, were admitted to the on-site Ebola holding unit. Since demand for beds in this unit greatly exceeded capacity, we aimed to improve the selection of patients with suspected Ebola virus disease for admission by identifying presenting clinical characteristics that were predictive of a confirmed diagnosis. METHODS: In this retrospective cohort study, we recorded the presenting clinical characteristics of suspected Ebola virus disease cases admitted to Connaught Hospital's Ebola holding unit. Patients were subsequently classified as confirmed Ebola virus disease cases or non-cases according to the result of Ebola virus reverse-transcriptase PCR (EBOV RT-PCR) testing. The sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratio of every clinical characteristic were calculated, to estimate the diagnostic accuracy and predictive value of each clinical characteristic for confirmed Ebola virus disease. RESULTS: Between May 29, 2014, and Dec 8, 2014, 850 patients with suspected Ebola virus disease were admitted to the holding unit, of whom 724 had an EBOV RT-PCR result recorded and were included in the analysis. In 464 (64%) of these patients, a diagnosis of Ebola virus disease was confirmed. Fever or history of fever (n=599, 83%), intense fatigue or weakness (n=495, 68%), vomiting or nausea (n=365, 50%), and diarrhoea (n=294, 41%) were the most common presenting symptoms in suspected cases. Presentation with intense fatigue, confusion, conjunctivitis, hiccups, diarrhea, or vomiting was associated with increased likelihood of confirmed Ebola virus disease. Three or more of these symptoms in combination increased the probability of Ebola virus disease by 3.2-fold (95% CI 2.3-4.4), but the sensitivity of this strategy for Ebola virus disease diagnosis was low. In a subgroup analysis, 15 (9%) of 161 confirmed Ebola virus disease cases reported neither a history of fever nor a risk factor for Ebola virus disease exposure. INTERPRETATION: Discrimination of Ebola virus disease cases from patients without the disease is a major challenge in an outbreak and needs rapid diagnostic testing. Suspected Ebola virus disease case definitions that rely on history of fever and risk factors for Ebola virus disease exposure do not have sufficient sensitivity to identify all cases of the disease. FUNDING: None.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Lado,M., Walker,N.F., Baker,P., Haroon,S., Brown,C.S., Youkee,D., Studd,N., Kessete,Q., Maini,R., Boyles,T., Hanciles,E., Wurie,A., Kamara,T.B., Johnson,O., Leather,A.J.
Original/Translated Title
URL
Date of Electronic
20150723
PMCID
Editors
Flying after diving: should recommendations be reviewed? In-flight echocardiographic study in bubble-prone and bubble-resistant divers 2015 DAN Europe Research Division, Contrada Padune 11, 64026 Roseto degli, Abruzzi (TE), Italy, Phone: +39(0)85-893-0333, Fax: +39-(0)85-893-0050, E-mail: dcialoni@daneurope.org.; DAN Europe Research Division, Roseto degli Abruzzi, Italy.; DAN Europe Research
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Diving and hyperbaric medicine
Periodical, Abbrev.
Diving.Hyperb.Med.
Pub Date Free Form
Mar
Volume
45
Issue
1
Start Page
10
Other Pages
15
Notes
JID: 101282742; OTO: NOTNLM; 2014/12/12 [received]; 2015/01/17 [accepted]; ppublish
Place of Publication
Australia
ISSN/ISBN
1833-3516; 1833-3516
Accession Number
PMID: 25964033
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
Output Language
Unknown(0)
PMID
25964033
Abstract
INTRODUCTION: Inert gas accumulated after multiple recreational dives can generate tissue supersaturation and bubble formation when ambient pressure decreases. We hypothesized that this could happen even if divers respected the currently recommended 24-hour pre-flight surface interval (PFSI). METHODS: We performed transthoracic echocardiography (TTE) on a group of 56 healthy scuba divers (39 male, 17 female) as follows: first echo--during the outgoing flight, no recent dives; second echo--before boarding the return flight, after a multiday diving week in the tropics and a 24-hour PFSI; third echo--during the return flight at 30, 60 and 90 minutes after take-off. TTE was also done after every dive during the week's diving. Divers were divided into three groups according to their 'bubble-proneness': non-bubblers, occasional bubblers and consistent bubblers. RESULTS: During the diving, 23 subjects never developed bubbles, 17 only occasionally and 16 subjects produced bubbles every day and after every dive. Bubbles on the return flight were observed in eight of the 56 divers (all from the 'bubblers' group). Two subjects who had the highest bubble scores during the diving were advised not to make the last dive (increasing their PFSI to approximately 36 hours), and did not demonstrate bubbles on the return flight. CONCLUSIONS: Even though a 24-hour PFSI is recommended on the basis of clinical trials showing a low risk of decompression sickness (DCS), the presence of venous gas bubbles in-flight in eight of 56 divers leads us to suspect that in real-life situations DCS risk after such a PFSI is not zero.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Cialoni,D., Pieri,M., Balestra,C., Marroni,A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Comparison of the size of persistent foramen ovale and atrial septal defects in divers with shunt-related decompression illness and in the general population 2015 Royal Stoke University Hospital Stoke-on-Trent, ST4 6QG, UK, E-mail: peter.wilmshurst@tiscali.co.uk.; Liverpool Heart and Chest Hospital, Liverpool, UK.; Our Lady's Hospital for Sick Children, Dublin, Ireland.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Diving and hyperbaric medicine
Periodical, Abbrev.
Diving.Hyperb.Med.
Pub Date Free Form
Jun
Volume
45
Issue
2
Start Page
89
Other Pages
93
Notes
LR: 20151119; JID: 101282742; 0 (Contrast Media); OTO: NOTNLM; 2015/03/30 [received]; 2015/05/01 [accepted]; ppublish
Place of Publication
Australia
ISSN/ISBN
1833-3516; 1833-3516
Accession Number
PMID: 26165530
Language
eng
SubFile
Comparative Study; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
26165530
Abstract
INTRODUCTION: Decompression illness (DCI) is associated with a right-to-left shunt, such as persistent foramen ovale (PFO), atrial septal defect (ASD) and pulmonary arteriovenous malformations. About one-quarter of the population have a PFO, but considerably less than one-quarter of divers suffer DCI. Our aim was to determine whether shunt-related DCI occurs mainly or entirely in divers with the largest diameter atrial defects. METHODS: Case control comparison of diameters of atrial defects (PFO and ASD) in 200 consecutive divers who had transcatheter closure of an atrial defect following shunt-related DCI and in an historic group of 263 individuals in whom PFO diameter was measured at post-mortem examination. RESULTS: In the divers who had experienced DCI, the median atrial defect diameter was 10 mm and the mean (standard deviation) was 9.9 (3.6) mm. Among those in the general population who had a PFO, the median diameter was 5 mm and mean was 4.9 (2.6) mm. The difference between the two groups was highly signi fi cant (P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Wilmshurst,P.T., Morrison,W.L., Walsh,K.P.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Development of a new sorptive extraction method based on simultaneous direct and headspace sampling modes for the screening of polycyclic aromatic hydrocarbons in water samples 2015 Departamento Quimica Analitica, Nutricion y Bromatologia, Instituto de Investigacion y Analisis Alimentario, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.; Departamento Quimica Analitica, Nutricion y Bromatologia, Instituto d
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Talanta
Periodical, Abbrev.
Talanta
Pub Date Free Form
Jan
Volume
132
Issue
Start Page
433
Other Pages
442
Notes
CI: Copyright (c) 2014; JID: 2984816R; 0 (Acenaphthenes); 0 (Acetonitriles); 0 (Drinking Water); 0 (Fluorenes); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Pyrenes); 0 (Silicones); 0 (Waste Water); 0 (Water Pollutants, Chemical); 1Z25C36811 (acenaphthylene)
Place of Publication
Netherlands
ISSN/ISBN
1873-3573; 0039-9140
Accession Number
PMID: 25476328
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.talanta.2014.09.044 [doi]
Output Language
Unknown(0)
PMID
25476328
Abstract
A new straightforward and inexpensive sample screening method for both EPA and EU priority polycyclic aromatic hydrocarbons (PAHs) in water has been developed. The method is based on combined direct immersion and headspace (DIHS) sorptive extraction, using low-cost disposable material, coupled to ultraperformance liquid chromatography with fluorescence and UV detection (UPLC-FD-UV). Extraction parameters, such as the sampling mode, extraction time and ionic strength were investigated in detail and optimized. Under optimized conditions, water samples (16 mL) were concentrated in silicone disks by headspace (HS) and direct immersion (DI) modes simultaneously, at room temperature for 9h for the majority of the 24 studied compounds. Ultrasound-assisted desorption of extracted analytes in acetonitrile was carried out also at room temperature. The optimized chromatographic method provided a good linearity (R>/=0.9991) and a broad linear range for all studied PAHs. The proposed analytical procedure exhibited a good precision level with relative standard deviations below 15% for all analytes. Quantification limits between 0.7 and 2.3 microg L(-1) and 0.16 and 3.90 ng L(-1) were obtained for compounds analyzed by UV (acenaphtylene, cyclopenta[c,d]pyrene and benzo[j]fluoranthene) and fluorescence, respectively. Finally, the proposed method was applied to the determination of PAHs in different real tap, river and wastewater samples.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Trinanes,S., Pena,M.T., Casais,M.C., Mejuto,M.C.
Original/Translated Title
URL
Date of Electronic
20141007
PMCID
Editors
Socio-demographic characteristics associated with cigarettes smoking, drug abuse and alcohol drinking among male medical university students in Iran 2015 Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Research Center for Behavioral Disorders an
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of research in health sciences
Periodical, Abbrev.
J.Res.Health.Sci.
Pub Date Free Form
Winter
Volume
15
Issue
1
Start Page
42
Other Pages
46
Notes
JID: 101480094; OTO: NOTNLM; 2014/10/10 [received]; 2015/01/03 [accepted]; 2014/12/19 [revised]; ppublish
Place of Publication
Iran
ISSN/ISBN
2228-7809; 2228-7795
Accession Number
PMID: 25821025
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
1828 [pii]
Output Language
Unknown(0)
PMID
25821025
Abstract
BACKGROUND: Substance abuse is one of the most complicated social problems. Understanding socio-demographic characteristics of those who abuse substances could help deal with this problem more efficiently. The main objective of this study was to determine socio-demographic characteristics associated with alcohol drinking, cigarettes smoking and drug abuse among a sample of male medical university students in Iran. METHODS: This cross-sectional study was conducted in 2014 among 425 male medical college students randomly selected with the proportional to size among different faculties in Isfahan and Kermanshah medical universities in Iran. A self-report written questionnaire was applied to collect data. Data were analyzed by the SPSS-20. RESULTS: Mean age of the respondents was 19.9 yr (ranging from 18 to 22 yr). About 19.4%, 3.9%, and 10.1% of the respondents had history of cigarette smoking, drug use, and alcohol drinking during the past three months, respectively. Logistic regression showed that mother's educational level, living place, economic status, and parents' divorce were the most influential predictive factors on substance abuse. CONCLUSIONS: Considering the high prevalence of substance abuse (especially smoking and alcohol drinking), it seems essential to design educational interventions to prevent substance abuse, paying attention to predictive factors mentioned above, among college students.
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Database
Publisher
Data Source
Authors
Jalilian,F., Karami Matin,B., Ahmadpanah,M., Ataee,M., Ahmadi Jouybari,T., Eslami,A.A., Mirzaei Alavijeh,M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors