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Is opium a real risk factor for esophageal cancer or just a methodological artifact? Hospital and neighborhood controls in case-control studies 2012
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Print(0)
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Journal Article
Periodical, Full
PLoS One
Periodical, Abbrev.
Pub Date Free Form
Volume
7
Issue
3
Start Page
e32711
Other Pages
e32711
Notes
ID: 22396792
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
BACKGROUND: Control selection is a major challenge in epidemiologic case-control studies. The aim of our study was to evaluate using hospital versus neighborhood control groups in studying risk factors of esophageal squamous cell carcinoma (ESCC). METHODOLOGY/PRINCIPAL FINDINGS: We compared the results of two different case-control studies of ESCC conducted in the same region by a single research group. Case definition and enrollment were the same in the two studies, but control selection differed. In the first study, we selected two age- and sex-matched controls from inpatient subjects in hospitals, while for the second we selected two age- and sex-matched controls from each subject's neighborhood of residence. We used the test of heterogeneity to compare the results of the two studies. We found no significant differences in exposure data for tobacco-related variables such as cigarette smoking, chewing Nass (a tobacco product) and hookah (water pipe) usage, but the frequency of opium usage was significantly different between hospital and neighborhood controls. Consequently, the inference drawn for the association between ESCC and tobacco use did not differ between the studies, but it did for opium use. In the study using neighborhood controls, opium use was associated with a significantly increased risk of ESCC (adjusted OR 1.77, 95% CI 1.17-2.68), while in the study using hospital controls, this was not the case (OR 1.09, 95% CI 0.63-1.87). Comparing the prevalence of opium consumption in the two control groups and a cohort enrolled from the same geographic area suggested that the neighborhood controls were more representative of the study base population for this exposure. CONCLUSIONS/SIGNIFICANCE: Hospital and neighborhood controls did not lead us to the same conclusion for a major hypothesized risk factor for ESCC in this population. Our results show that control group selection is critical in drawing appropriate conclusions in observational studies.
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Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Shakeri,Ramin, Kamangar,Farin, Nasrollahzadeh,Dariush, Nouraie,Mehdi, Khademi,Hooman, Etemadi,Arash, Islami,Farhad, Marjani,Hajiamin, Fahimi,Saman, Sepehr,Alireza, Rahmati,Atieh, Abnet,Christian C., Dawsey,Sanford M., Brennan,Paul, Boffetta,Paolo, Malekzadeh,Reza, Majdzadeh,Reza
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
In vitro cytotoxicity and mutagenicity of mainstream waterpipe smoke and its functional consequences on alveolar type II derived cells 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Toxicol Lett
Periodical, Abbrev.
Toxicol.Lett.
Pub Date Free Form
Volume
211
Issue
3
Start Page
220
Other Pages
31
Notes
ID: 22516759
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
INTRODUCTION: While waterpipe tobacco smoking has become a global phenomenon, its potential health consequences are poorly understood. In this manuscript, we report the in vitro mutagenicity of waterpipe smoke condensate (WSC), the alteration in cellular parameters of lung alveolar cells in response to WSC exposure and discuss the implication of cellular responses in the pathophysiology of chronic obstructive pulmonary disease (COPD). METHODS: The mainstream WSC was generated using a standard laboratory machine protocol. We assessed its mutagenicity using Ames test. In addition, we studied the effect of WSC on the proliferation and cell cycle of alveolar type II cells and vascular endothelial cells. We also assessed the effect of WSC on the expression of genes involved in cell cycle arrest and inflammation. RESULTS: Within the range of tested doses, WSC did not elicit sufficient response to be considered mutagenic in any of the strains tested (TA98, TA100, TA102, and TA97a) but were found to be toxic for strains TA97a and TA102 at the highest tested doses. However, WSC induced cell cycle arrest and cellular senescence mediated by the p53-p21 pathway. Also our study indicated that WSC induced an increase in the transcriptional expression of matrix metalloproteinases, MMP-2 and MMP-9 and an immune response regulator, Toll Like Receptor-4. CONCLUSION: The data reported here represent the first in vitro demonstration of the effect of waterpipe smoke on cellular parameters providing evidence of the potential involvement of WPS in the pathogenesis of COPD through impairing cellular growth and inducing inflammation.
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Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Rammah,Mayyasa, Dandachi,Farah, Salman,Rola, Shihadeh,Alan, El-Sabban, Marwan
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Happy hookah hour 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Curr Opin Pulm Med
Periodical, Abbrev.
Curr.Opin.Pulm.Med.
Pub Date Free Form
Volume
18
Issue
2
Start Page
95
Other Pages
6
Notes
ID: 22234276
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://dx.doi.org/10.1097/MCP.0b013e328350266d
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Varkey,Basil
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe smoking: a new tobacco pandemic entailing severe health risks? 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Arch Toxicol
Periodical, Abbrev.
Arch.Toxicol.
Pub Date Free Form
Volume
86
Issue
8
Start Page
1161
Other Pages
2
Notes
ID: 22684767
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://dx.doi.org/10.1007/s00204-012-0885-4
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Luch,Andreas
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Keeping the night going: the role of hookah bars in evening drinking behaviours 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Public health
Periodical, Abbrev.
Public Health
Pub Date Free Form
Volume
126
Issue
12
Start Page
1078
Other Pages
81
Notes
ID: 22819668
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://dx.doi.org/10.1016/j.puhe.2012.06.010
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Soule,E K., Barnett,T E., Curbow,B A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Prevention and sporadic carbon monoxide poisoning related to shisha (hookah, narghile) tobacco smoking 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
J Emerg Med
Periodical, Abbrev.
J.Emerg.Med.
Pub Date Free Form
Volume
42
Issue
1
Start Page
65
Other Pages
6
Notes
ID: 20133102
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://dx.doi.org/10.1016/j.jemermed.2009.11.027
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Chaouachi,Kamal
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Inhaling smoke causes smoke inhalation: put that in your hookah pipe! 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
CJEM
Periodical, Abbrev.
Pub Date Free Form
Volume
14
Issue
1
Start Page
3
Other Pages
4
Notes
ID: 22417949
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://pesquisa.bvsalud.org/ghl/resource/en/mdl-22417949
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Sivilotti,Marco L.A., Abu-Laban, Riyad
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe smoking 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
East Mediterr Health J
Periodical, Abbrev.
East.Mediterr.Health J.
Pub Date Free Form
Volume
18
Issue
10
Start Page
995
Other Pages
995
Notes
ID: 23301352
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://pesquisa.bvsalud.org/ghl/resource/en/mdl-23301352
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe tobacco smoking and cigarette equivalence 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Br J Gen Pract
Periodical, Abbrev.
Br.J.Gen.Pract.
Pub Date Free Form
Volume
62
Issue
596
Start Page
127
Other Pages
127
Notes
ID: 22429419
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Masters,Nigel, Tutt,Catherine, Yaseen,Nisar
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Reinventamos un niño a través de la forma tridimensional: Roberto con la Gorra 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Periodical, Abbrev.
Rev.CES psicol
Pub Date Free Form
Volume
5
Issue
1
Start Page
102
Other Pages
111
Notes
ID: 666903
Place of Publication
ISSN/ISBN
Accession Number
Language
es
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Du moment que nous proposons dans la cure d’enfants un support plastique comme le dessin, la pâte à modeler ou la plasteline en tant que médiateur thérapeutique,nous produisons une résonance d’une autre plasticité, une plasticité psychique qui s’oppose à la structure rigide du symptôme. Avec les enfants, en particulier, nous sommes souvent surpris de la ® plasticité » dont ils sont porteurs au cours du travail psychothérapeutique. Nous souhaitons rendre compte du parcours de plasticité psychique d’un enfant de cinq ans, parcours au cours duquel il lui a été possible de réinventer un autre enfant, celui de la représentation psychique. Cette nouvelle représentation de lui-même, acquise par son travail psychothérapique, a changé sa position subjective et a eu des effets sur sa souffrance. Le cas évoqué est celui d’un enfant qui utilise l’argile de modelage, support plastique particulièrement intéressant car il permet de se placer au ® centre de la chose corporelle » et de sa figuration. Ce cas a été l’illustration d’un autre article (Bayro-Corrochano, 1999). Nous le reprenons ici dans une forme épurée.(AU)
Descriptors
Links
http://revistas.ces.edu.co/index.php/psicologia/article/download/2092/1455
Book Title
Database
LILACS; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Bayro-Corrochano, Fernandi
Original/Translated Title
URL
Date of Electronic
PMCID
Editors