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Prevalence of substance use among college students in Eldoret, western Kenya 2011 Department of Mental Health, Moi University School of Medicine, PO Box 4606, Eldoret 30100, Kenya. lukoye@gmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC psychiatry
Periodical, Abbrev.
BMC Psychiatry
Pub Date Free Form
28-Feb
Volume
11
Issue
Start Page
34
Other Pages
244X-11-34
Notes
LR: 20151119; JID: 100968559; OID: NLM: PMC3053226; 2010/11/30 [received]; 2011/02/28 [accepted]; 2011/02/28 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-244X; 1471-244X
Accession Number
PMID: 21356035
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-244X-11-34 [doi]
Output Language
Unknown(0)
PMID
21356035
Abstract
BACKGROUND: Substance use among college and university students predicts substance related problems in later life. Few studies on this phenomenon have been carried out in low income countries, and most focus on primary and secondary school students. This study therefore aimed to establish the prevalence and factors associated with drug use among university and college students in a low income country. METHODS: DESIGN: A descriptive cross-sectional survey using the Self-Administered WHO Model Core Questionnaire to collect information on use of various drugs among students in colleges and university campuses within Eldoret Municipality in Western Kenya. SETTING: Four tertiary learning institutions in Eldoret Municipality were randomly selected for inclusion in the study- three tertiary level non-university institutions and one university campus. SUBJECTS: Five hundred students who gave consent to participate in the study, 125 from each of the four participating institutions. The mean age was 22.9 years (18-32, s.d. 2.5), and males made up 52.2% of the sample. RESULTS: Lifetime prevalence rate of any substance use was 69.8%, and none of the socio-demographic factors was significantly associated with this. Lifetime prevalence rate of alcohol use was 51.9%, and 97.6% of alcohol users had consumed alcohol in the week prior to the study. The prevalence rate of cigarette use was 42.8%, with males having statistically significantly higher rates than females (p
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Atwoli,L., Mungla,P.A., Ndung'u,M.N., Kinoti,K.C., Ogot,E.M.
Original/Translated Title
URL
Date of Electronic
20110228
PMCID
PMC3053226
Editors
A persisting secondhand smoke hazard in urban public places: results from fine particulate (PM2.5) air sampling 2011 Department of Public Health, University of Otago Wellington, PO Box 7343 Wellington South, New Zealand. nick.wilson@otago.ac.nz
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The New Zealand medical journal
Periodical, Abbrev.
N.Z.Med.J.
Pub Date Free Form
4-Mar
Volume
124
Issue
1330
Start Page
34
Other Pages
47
Notes
JID: 0401067; 0 (Hazardous Substances); 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); CIN: N Z Med J. 2011 Mar 4;124(1330):5-7. PMID: 21681245; epublish
Place of Publication
New Zealand
ISSN/ISBN
1175-8716; 0028-8446
Accession Number
PMID: 21681251
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
Output Language
Unknown(0)
PMID
21681251
Abstract
AIM: To assess the need for additional smokefree settings, by measuring secondhand smoke (SHS) in a range of public places in an urban setting. METHODS: Measurements were made in Wellington City during the 6-year period after the implementation of legislation that made indoor areas of restaurants and bars/pubs smokefree in December 2004, and up to 20 years after the 1990 legislation making most indoor workplaces smokefree. Fine particulate levels (PM2.5) were measured with a portable real-time airborne particle monitor. We collated data from our previously published work involving random sampling, purposeful sampling and convenience sampling of a wide range of settings (in 2006) and from additional sampling of selected indoor and outdoor areas (in 2007-2008 and 2010). RESULTS: The "outdoor" smoking areas of hospitality venues had the highest particulate levels, with a mean value of 72 mcg/m3 (range of maximum values 51-284 mcg/m3) (n=20 sampling periods). These levels are likely to create health hazards for some workers and patrons (i.e., when considered in relation to the WHO air quality guidelines). National survey data also indicate that these venues are the ones where SHS exposure is most frequently reported by non-smokers. Areas inside bars that were adjacent to "outdoor" smoking areas also had high levels, with a mean of 54 mcg/m3 (range of maximum values: 18-239 mcg/m3, for n=13 measurements). In all other settings mean levels were lower (means: 2-22 mcg/m3). These other settings included inside traditional style pubs/sports bars (n=10), bars (n=18), restaurants (n=9), cafes (n=5), inside public buildings (n=15), inside transportation settings (n=15), and various outdoor street/park settings (n=22). During the data collection in all settings made smokefree by law, there was only one occasion of a person observed smoking. CONCLUSIONS: The results suggest that compliance in pubs/bars and restaurants has remained extremely high in this city in the nearly six years since implementation of the upgraded smokefree legislation. The results also highlight additional potential health gain from extending smokefree policies to reduce SHS exposure in the "outdoor" smoking areas of hospitality venues and to reduce SHS drift from these areas to indoor areas.
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Database
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Data Source
Authors
Wilson,N., Edwards,R., Parry,R.
Original/Translated Title
URL
Date of Electronic
20110304
PMCID
Editors
Additive antifungal activity of anidulafungin and human neutrophils against Candida parapsilosis biofilms 2011 Laboratory of Infectious Diseases, 3rd Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of antimicrobial chemotherapy
Periodical, Abbrev.
J.Antimicrob.Chemother.
Pub Date Free Form
Mar
Volume
66
Issue
3
Start Page
588
Other Pages
591
Notes
LR: 20130527; JID: 7513617; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Tetrazolium Salts); 0 (Triazoles); 117038-70-7 (2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazoliu m hydroxide); 9HLM53094I (anidulafungin); 2010/12/07
Place of Publication
England
ISSN/ISBN
1460-2091; 0305-7453
Accession Number
PMID: 21138910
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/jac/dkq466 [doi]
Output Language
Unknown(0)
PMID
21138910
Abstract
OBJECTIVES: To investigate the activities of two newer triazoles and two echinocandins combined with human phagocytes against Candida parapsilosis biofilms. METHODS: An in vitro model of C. parapsilosis biofilms was used. Biofilms were grown on silicone elastomer discs in 96-well plates at 37 degrees C for 72 h. Biofilms or planktonic cells were incubated with voriconazole, posaconazole, caspofungin or anidulafungin, at clinically relevant concentrations, and human phagocytes (neutrophils or monocytes) alone or in combination with each of the antifungal agents for a further 22 h. Fungal damage induced by antifungal agents and/or phagocytes was determined by XTT [2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)2H-tetrazolium-5-carboxanilide] metabolic assay. RESULTS: Each of the antifungal agents alone and in combination with human phagocytes induced less damage against C. parapsilosis biofilms compared with planktonic cells. No antagonistic interactions between antifungal agents and phagocytes were found. Furthermore, anidulafungin, but not caspofungin, and neutrophils exerted additive activity against C. parapsilosis biofilms. CONCLUSIONS: Besides a lack of antagonistic interactions between newer antifungal agents and phagocytes, anidulafungin exerts additive immunopharmacological activity against C. parapsilosis biofilms.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Katragkou,A., Chatzimoschou,A., Simitsopoulou,M., Georgiadou,E., Roilides,E.
Original/Translated Title
URL
Date of Electronic
20101207
PMCID
Editors
Flavored waters: influence of ingredients on antioxidant capacity and terpenoid profile by HS-SPME/GC-MS 2011 Requimte/Faculdade de Farmacia, Universidade do Porto, Porto, Portugal.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of Agricultural and Food Chemistry
Periodical, Abbrev.
J.Agric.Food Chem.
Pub Date Free Form
11-May
Volume
59
Issue
9
Start Page
5062
Other Pages
5072
Notes
LR: 20131121; JID: 0374755; 0 (Antioxidants); 0 (Flavoring Agents); 0 (Terpenes); 059QF0KO0R (Water); 2011/04/04 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1520-5118; 0021-8561
Accession Number
PMID: 21462928
Language
eng
SubFile
Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1021/jf1048244 [doi]
Output Language
Unknown(0)
PMID
21462928
Abstract
The antioxidant profiles of 39 water samples (29 flavored waters based on 10 natural waters) and 6 flavors used in their formulation (furnished by producers) were determined. Total phenol and flavonoid contents, reducing power, and DPPH radical scavenging activity were the optical techniques implemented and included in the referred profile. Flavor extracts were analyzed by HS-SPME/GC-MS to obtain the qualitative and quantitative profiles of the volatile fraction of essential oils. Results pointed out a higher reducing power (0.14-11.8 mg of gallic acid/L) and radical scavenging activity (0.29-211.5 mg Trolox/L) of flavored waters compared with the corresponding natural ones, an interesting fact concerning human health. Bioactive compounds, such as polyphenols, were present in all samples (0.5-359 mg of gallic acid/L), whereas flavonoids were not present either in flavored waters or in flavors. The major components of flavor extracts were monoterpenes, such as citral, alpha-limonene, carveol, and alpha-terpineol.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Barroso,M.F., Noronha,J.P., Delerue-Matos,C., Oliveira,M.B.
Original/Translated Title
URL
Date of Electronic
20110404
PMCID
Editors
Did unprogrammed tobacco control efforts over seven years decrease smoking prevalence in the medical school? 2011 Department of Chest Diseases, Faculty of Medicine, Trakya University, Edirne, Turkey. celalk@trakya.edu.tr
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tuberkuloz ve toraks
Periodical, Abbrev.
Tuberk.Toraks
Pub Date Free Form
Volume
59
Issue
1
Start Page
18
Other Pages
26
Notes
JID: 0417364; 0 (Tobacco Smoke Pollution); ppublish
Place of Publication
Turkey
ISSN/ISBN
0494-1373; 0494-1373
Accession Number
PMID: 21554226
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
21554226
Abstract
Medical students will have significant roles in combating against death tool of tobacco. The aim of this study is to evaluate whether any decrease in the smoking prevalence of the medical students over seven years of many tobacco control efforts. A self-administered questionnaire was carried out among 764 of 854 (89.4%) medical students in order to determine the knowledge, attitudes and behaviors towards tobacco use. Chi-square tests, Student's t-test and multiple logistic regression methods were used. Results were compared with the historical control study that was done seven years ago with same methods. 25.9% of the students were smoker (36.6% of males, 16.3% of females), 4.9% was exsmoker and 69.2% was non-smoker. Quit rate was high among males than females (6.8% versus 3.3%, p
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Database
Publisher
Data Source
Authors
Karlikaya,C., Ozdemir,L.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Transitions between the stages of smoking in Iranian adolescents 2011 National Public Health Management Center (NPMC), Tabriz University of Medical Sciences, Tabriz, Iran. poorasl@yahoo.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Preventive medicine
Periodical, Abbrev.
Prev.Med.
Pub Date Free Form
Feb
Volume
52
Issue
2
Start Page
136
Other Pages
138
Notes
LR: 20120508; CI: Copyright (c) 2010; JID: 0322116; 2010/06/09 [received]; 2010/11/24 [revised]; 2010/11/25 [accepted]; 2010/12/09 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1096-0260; 0091-7435
Accession Number
PMID: 21145915
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.ypmed.2010.11.024 [doi]
Output Language
Unknown(0)
PMID
21145915
Abstract
OBJECTIVE: This study examined the prevalence of smoking, the rates of transitions, and predictors of transition through the three stages of smoking. METHODS: A total of 1785 high school students in Tabriz (northwest of Iran) were assessed at 2 time points with a 12-month interval in 2005 and 2006, regarding changes in smoking stages. The predictor variables were measured when the students were in the 10th grade. Logistic regression was employed to predict the different smoking stages at grade 11. RESULTS: The results showed that 14.3% (95% confidence interval, 12.3%-16.4%) and 2.8% (2.0%-4.0%) of the never smokers became experimenters and regular smokers, respectively, whereas 16.5% (12.4%-21.7%) of the experimenters became regular smokers. Among never smokers, participation in groups with at least one smoker (odds ratio, 1.24 (95% confidence interval, 1.05-1.47)), having smoker friends (1.85 (1.21-2.83)), and a positive attitude toward smoking (1.22 (1.02-1.46)) predicted smoking experience. Among the experimenters, those who had general risk behaviors (2.56 (1.12-5.87)) and participated in groups with at least one smoker (2.58 (1.26-5.31)) significantly progressed to becoming a regular smoker at the follow-up. CONCLUSION: Prevention of smoking in adolescence should begin by focusing on the predictors of transition through smoking stages, especially participating in smoker groups.
Descriptors
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Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Mohammadpoorasl,A., Fakhari,A., Shamsipour,M., Rostami,F., Rashidian,H.
Original/Translated Title
URL
Date of Electronic
20101209
PMCID
Editors
Predictors of short-term success in smoking cessation in relation to attendance at a smoking cessation program 2011 Institute of Social Medicine, Centre for Public Health, Medical University of Vienna, Rooseveltplatz 3, 1090 Wien, Austria. thomas.dorner@meduniwien.ac.at
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Nov
Volume
13
Issue
11
Start Page
1068
Other Pages
1075
Notes
LR: 20151119; JID: 9815751; 6M3C89ZY6R (Nicotine); 7U1EE4V452 (Carbon Monoxide); 2011/08/10 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 21832273
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/ntr/ntr179 [doi]
Output Language
Unknown(0)
PMID
21832273
Abstract
INTRODUCTION: The identification of individual characteristics that predict success in smoking cessation is necessary to improve the effectiveness of smoking cessation efforts. The aim of this study was to identify the factors that predict success in smoking cessation in people who attended 2, 3, 4, or 5 sessions of a smoking cessation program. METHODS: The participants comprised 2,471 people who attended at least 2 consultations during a 5-week smoking cessation program. Success in smoking cessation was defined as self-reported abstinence and having an exhaled carbon monoxide level =10 parts per million at the final consultation. Baseline characteristics were compared using univariate analysis of variance and the chi-square test. A stepwise multivariate logistic regression model was used to analyze the effect of baseline characteristics and the slopes of the withdrawal symptoms on the success in smoking cessation. RESULTS: Participating in a higher number of sessions gradually increased the chance of smoking cessation from 12.1% to 61.2% (p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Dorner,T.E., Trostl,A., Womastek,I., Groman,E.
Original/Translated Title
URL
Date of Electronic
20110810
PMCID
Editors
Investigation of antifungal susceptibilities and some virulence factors of Candida strains isolated from blood cultures and genotyping by RAPD-PCR 2011 Adnan Menderes University Faculty of Medicine, Department of Medical Microbiology, Aydin, Turkey. gultekinberna@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Mikrobiyoloji bulteni
Periodical, Abbrev.
Mikrobiyol.Bul.
Pub Date Free Form
Apr
Volume
45
Issue
2
Start Page
306
Other Pages
317
Notes
JID: 7503830; 0 (Antifungal Agents); 0 (Virulence Factors); EC 3.1.- (Esterases); EC 3.1.- (Phospholipases); ppublish
Place of Publication
Turkey
ISSN/ISBN
0374-9096; 0374-9096
Accession Number
PMID: 21644074
Language
tur
SubFile
English Abstract; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
21644074
Abstract
Candidemia is a serious clinical picture with a rather high mortality. Early diagnosis and appropriate treatment is crucial in this picture especially in immunocompromised cases. The aims of this retrospective study were to investigate the antifungal susceptibility patterns and to detect the presence of phospholipase, esterase and biofilm production which are excepted as virulence factors of Candida spp. strains and to evaluate the clonal relationships between isolates. A total of 46 Candida spp. Strains isolated from blood cultures of patients of whom eight were newborn and 38 were adults, between the period of February 2005 to July 2010, were included in the study. Of the isolates 17 were identified as C.albicans, 18 were C.parapsilosis, five were C.glabrata, four were C.tropicalis, one was C.guilliermondii and one was C.krusei. Antifungal susceptibility tests were performed by using "Sensititre Yeast One (Trek Diagnostic Systems, USA)" commercial kit. Esterase activity was detected in Tween-80 medium; phospholipase activity in yolk egg agar and biofilm formation was investigated by microplate assay. Strain genotyping was performed by RAPD-PCR (random amplified polymorphic DNA-polymerase chain reaction) by using OPE-03, OPE-18, AP50-1, Cnd-3 and Cnd-4 primers. All strains were found to be susceptible to amphotericin B, voriconazole, posaconazole, and caspofungin. C.krusei strain was defined as resistant (intrinsically) to fluconazole. All strains of C.albicans, C.parapsilosis, C.glabrata, and C.tropicalis were found to be susceptible to fluconazole. Three of five C.glabrata strains were resistant to itraconazole, while the other strains were found to be susceptible. All of the C.albicans strains had phospholipase and esterase activity, however none were biofilm-producing isolates. In contrast all of the C.parapsilosis strains were negative for phospholipase and esterase activity, however all were positive for biofilm formation. Phospholipase activity has not been detected in non-albicans strains; esterase activity were found positive in all of the C.tropicalis strains, while biofilm formation was detected in three C.tropicalis, one C.glabrata and one C.krusei isolates. The results of genotyping demonstrated that C.albicans strains displayed 5-8 different patterns and C. Parapsilosis strains 2-3 patterns with the use of five primers. Among C.parapsilosis strains, 14 were found identical (with the use of all the primers forming a single pattern (pattern A). In conclusion, the Candida spp. Isolated from blood samples were highly susceptible to the tested antifungals, and C.albicans strains had high phospholipase and esterase activity, while C.parapsilosis strains had high rate of positivity for biofilm formation. The predominant pattern amongst C.parapsilosis strains was thought to be related to exogenous dissemination.
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Book Title
Database
Publisher
Data Source
Authors
Gultekin,B., Eyigor,M., Tiryaki,Y., Kirdar,S., Aydin,N.
Original/Translated Title
Kan Kulturlerinden Izole Edilen Candida Suslarinda Antifungal Duyarliligin ve Bazi Virulans Faktorlerinin Arastirilmasi ve RAPD-PCR ile Genotiplendirilmesi
URL
Date of Electronic
PMCID
Editors
Nitrogen uptake and preference in a forest understory following invasion by an exotic grass 2011 Department of Natural Resources and Environmental Sciences, University of Illinois, Urbana, IL 61801, USA. jmf@illinois.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Oecologia
Periodical, Abbrev.
Oecologia
Pub Date Free Form
Nov
Volume
167
Issue
3
Start Page
781
Other Pages
791
Notes
LR: 20151119; JID: 0150372; 0 (Nitrogen Isotopes); N762921K75 (Nitrogen); 2010/11/08 [received]; 2011/05/12 [accepted]; 2011/05/29 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1432-1939; 0029-8549
Accession Number
PMID: 21625979
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; IM
DOI
10.1007/s00442-011-2030-0 [doi]
Output Language
Unknown(0)
PMID
21625979
Abstract
Plant-soil interactions have been proposed as a causative mechanism explaining how invasive plant species impact ecosystem processes. We evaluate whether an invasive plant influences plant and soil-microbe acquisition of nitrogen to elucidate the mechanistic pathways by which invaders might alter N availability. Using a (15)N tracer, we quantify differences in nitrogen uptake and allocation in communities with and without Microstegium vimineum, a shade-tolerant, C(4) grass that is rapidly invading the understories of eastern US deciduous forests. We further investigate if plants or the microbial biomass exhibit preferences for certain nitrogen forms (glycine, nitrate, and ammonium) to gain insight into nitrogen partitioning in invaded communities. Understory native plants and M. vimineum took up similar amounts of added nitrogen but allocated it differently, with native plants allocating primarily to roots and M. vimineum allocating most nitrogen to shoots. Plant nitrogen uptake was higher in invaded communities due primarily to the increase in understory biomass when M. vimineum was present, but for the microbial biomass, nitrogen uptake did not vary with invasion status. This translated to a significant reduction (P
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Fraterrigo,J.M., Strickland,M.S., Keiser,A.D., Bradford,M.A.
Original/Translated Title
URL
Date of Electronic
20110529
PMCID
Editors
Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains 2011 Department of Medical Microbiology, University Medical Centre Utrecht, the Netherlands. m.leversteinvhall@umcutrecht.nl
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Print(0)
Ref Type
Journal Article
Periodical, Full
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Periodical, Abbrev.
Clin.Microbiol.Infect.
Pub Date Free Form
Jun
Volume
17
Issue
6
Start Page
873
Other Pages
880
Notes
CI: 2011 The Authors. Clinical Microbiology and Infection; 2011; JID: 9516420; EC 3.5.2.6 (beta-Lactamases); 2011/04/04 [aheadofprint]; ppublish
Place of Publication
France
ISSN/ISBN
1469-0691; 1198-743X
Accession Number
PMID: 21463397
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1111/j.1469-0691.2011.03497.x [doi]
Output Language
Unknown(0)
PMID
21463397
Abstract
Intestinal carriage of extended-spectrum beta-lactamase (ESBL) -producing bacteria in food-producing animals and contamination of retail meat may contribute to increased incidences of infections with ESBL-producing bacteria in humans. Therefore, distribution of ESBL genes, plasmids and strain genotypes in Escherichia coli obtained from poultry and retail chicken meat in the Netherlands was determined and defined as 'poultry-associated' (PA). Subsequently, the proportion of E. coli isolates with PA ESBL genes, plasmids and strains was quantified in a representative sample of clinical isolates. The E. coli were derived from 98 retail chicken meat samples, a prevalence survey among poultry, and 516 human clinical samples from 31 laboratories collected during a 3-month period in 2009. Isolates were analysed using an ESBL-specific microarray, sequencing of ESBL genes, PCR-based replicon typing of plasmids, plasmid multi-locus sequence typing (pMLST) and strain genotyping (MLST). Six ESBL genes were defined as PA (bla(CTX-M-1) , bla(CTX-M-2) , bla(SHV-2) , bla(SHV-12) , bla(TEM-20) , bla(TEM-52) ): 35% of the human isolates contained PA ESBL genes and 19% contained PA ESBL genes located on IncI1 plasmids that were genetically indistinguishable from those obtained from poultry (meat). Of these ESBL genes, 86% were bla(CTX-M-1) and bla(TEM-52) genes, which were also the predominant genes in poultry (78%) and retail chicken meat (75%). Of the retail meat samples, 94% contained ESBL-producing isolates of which 39% belonged to E. coli genotypes also present in human samples. These findings are suggestive for transmission of ESBL genes, plasmids and E. coli isolates from poultry to humans, most likely through the food chain.
Descriptors
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Book Title
Database
Publisher
European Society of Clinical Microbiology and Infectious Diseases
Data Source
Authors
Leverstein-van Hall,M.A., Dierikx,C.M., Cohen Stuart,J., Voets,G.M., van den Munckhof,M.P., van Essen-Zandbergen,A., Platteel,T., Fluit,A.C., van de Sande-Bruinsma,N., Scharinga,J., Bonten,M.J., Mevius,D.J., National ESBL surveillance group
Original/Translated Title
URL
Date of Electronic
20110404
PMCID
Editors