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Cadmium and nickel in blood of Tunisian population and risk of nasosinusal polyposis disease 2015 Unit of Marine and Environmental Toxicology, UR 09-03, Sfax University, IPEIS, BP 1172, 3018, Sfax, Tunisia, rimkhlifi@yahoo.fr.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science and pollution research international
Periodical, Abbrev.
Environ.Sci.Pollut.Res.Int.
Pub Date Free Form
Mar
Volume
22
Issue
5
Start Page
3586
Other Pages
3593
Notes
JID: 9441769; 0 (Environmental Pollutants); 00BH33GNGH (Cadmium); 7OV03QG267 (Nickel); 2014/06/06 [received]; 2014/09/16 [accepted]; 2014/09/26 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1614-7499; 0944-1344
Accession Number
PMID: 25253060
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s11356-014-3619-8 [doi]
Output Language
Unknown(0)
PMID
25253060
Abstract
Nasosinusal polyposis (NSP) is a chronic inflammatory disease of the nasal mucosa. Although the pathophysiology underlying NSP formation is not fully understood, environmental factors appear to be contributed the development of this disease. A case-control study of Tunisian patients was examined to assess the levels of cadmium (Cd) and nickel (Ni) in blood and reparse the association between the exposure to these metals and the risk of nasosinusal polyposis disease. Mean blood levels of Cd in patients (2.2 +/- 12.8 mug/L) were significantly higher than those of controls (0.5 +/- 0.7 mug/L). Levels of blood Cd were positively correlated with tobacco smoking and chewing among controls. The Cd and Ni concentrations among control (p = 0.001) and patient (p = 0.018) tobacco consumers (smoking, chewing, and shisha) were significantly higher than those nonconsumers. Additionally, Ni blood levels of patient and control smokers were significantly higher than those of nonsmokers. Cd levels in blood samples of NSP patients occupationally exposed for more than 14 years were eight times higher than that of nonexposed. Drinking water was also found to be incriminated as exposure sources. Among risk factors, shisha consumption, environmental exposure, and occupational exposure presented the most significant association with NSP disease (odds ratio (OR) = 14.1, 10.1, and 1.7, respectively). High levels of blood Cd (OR = 3.5) were strongly associated with NSP disease (p = 0.027). Ni blood levels were shown to be associated with the four stages of polyps in both nasal cavities (right and left) (p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Khlifi,R., Olmedo,P., Gil,F., Hammami,B., Hamza-Chaffai,A.
Original/Translated Title
URL
Date of Electronic
20140926
PMCID
Editors
Association between blood arsenic levels and nasal polyposis disease risk in the Tunisian population 2015 Unit of Marine and Environmental Toxicology, UR 09-03, Sfax University, IPEIS, BP 1172, 3018, Sfax, Tunisia, rimkhlifi@yahoo.fr.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science and pollution research international
Periodical, Abbrev.
Environ.Sci.Pollut.Res.Int.
Pub Date Free Form
Sep
Volume
22
Issue
18
Start Page
14136
Other Pages
14143
Notes
JID: 9441769; N712M78A8G (Arsenic); 2014/12/06 [received]; 2015/05/06 [accepted]; 2015/05/13 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1614-7499; 0944-1344
Accession Number
PMID: 25966890
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s11356-015-4666-5 [doi]
Output Language
Unknown(0)
PMID
25966890
Abstract
Although the pathophysiology underlying nasal polyposis (NP) formation is not fully understood, systemic, local, and environmental factors appear to contribute to NP disease development. This study aimed to explore the relationship between metal blood levels and NP risk. To the best of our knowledge, the current research represents the first scientific contribution reporting levels of Cr and As in blood of NP patients. In this context, 90 NP patients and 171 controls were recruited and blood samples were analyzed to determine the concentrations of As and Cr. Metal blood levels of As in patients (2.1 mug/L) were significantly higher than those of controls (1.2 mug/L). However, no significant difference in blood Cr levels was found between cases and controls. Arsenic blood levels of cigarette smokers were significantly higher than those of non-smokers. Environmental exposure and shisha consumption presented the most significant association with NP disease (OR = 10.1 and 14.1, respectively). High levels of blood As were significantly associated with NP disease (OR = 2.1). Cr blood levels were found to be associated with the four stages of polyps in both nasal cavities. This study found a strong association between nasal polyposis disease and As blood levels. These findings merit further investigation.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Khlifi,R., Olmedo,P., Gil,F., Chakroun,A., Hamza-Chaffai,A.
Original/Translated Title
URL
Date of Electronic
20150513
PMCID
Editors
Blood nickel and chromium levels in association with smoking and occupational exposure among head and neck cancer patients in Tunisia 2013 Unit of Marine and Environmental Toxicology, UR 09-03, Sfax University, IPEIS, BP 1172, 3018, Sfax, Tunisia, rimkhlifi@yahoo.fr.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science and pollution research international
Periodical, Abbrev.
Environ.Sci.Pollut.Res.Int.
Pub Date Free Form
Nov
Volume
20
Issue
11
Start Page
8282
Other Pages
8294
Notes
JID: 9441769; 0 (Environmental Pollutants); 0R0008Q3JB (Chromium); 7OV03QG267 (Nickel); CIN: Environ Sci Pollut Res Int. 2013 Nov;20(11):8297. PMID: 23975708; CIN: Environ Sci Pollut Res Int. 2013 Nov;20(11):8295-6. PMID: 23807563; 2012/10/08 [received];
Place of Publication
Germany
ISSN/ISBN
1614-7499; 0944-1344
Accession Number
PMID: 23625117
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s11356-013-1466-7 [doi]
Output Language
Unknown(0)
PMID
23625117
Abstract
Chronic exposure to chromium (Cr) and nickel (Ni) has long been recognized as being capable to increase head and neck cancer (HNC) incidence among exposed human populations. This study represents the first biomonitoring of Cr and Ni exposure in Tunisia and focuses on a possible association with HNC risk. The aim of the present study was to evaluate the concentrations of Cr and Ni in the blood of HNC patients and controls. Metals blood levels of 169 HNC patients and 351 controls were determined using a Perkin-Elmer Analyst 800 Atomic Absorption Spectrometer. Mean blood levels of Cr and Ni in HNC cases (52.15 and 111.60 mug/L, respectively) were significantly higher than those of controls (37.04 and 30.50 mug/L, respectively). Cases' blood levels of Cr and Ni were significantly higher than those of controls after controlling for the other risk factors of HNC, including smoking, shisha consumption, occupational exposure, and nearby environment (P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Khlifi,R., Olmedo,P., Gil,F., Feki-Tounsi,M., Chakroun,A., Rebai,A., Hamza-Chaffai,A.
Original/Translated Title
URL
Date of Electronic
20130428
PMCID
Editors
Cadmium in blood of Tunisian men and risk of bladder cancer: interactions with arsenic exposure and smoking 2013 Unit of Marine and Environmental Toxicology. IPEIS, University of Sfax, BP 805, 3018, Sfax, Tunisia, molkafekitounsi@yahoo.fr.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science and pollution research international
Periodical, Abbrev.
Environ.Sci.Pollut.Res.Int.
Pub Date Free Form
Oct
Volume
20
Issue
10
Start Page
7204
Other Pages
7213
Notes
JID: 9441769; 0 (Carcinogens); 00BH33GNGH (Cadmium); N712M78A8G (Arsenic); 2013/01/23 [received]; 2013/04/02 [accepted]; 2013/05/15 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1614-7499; 0944-1344
Accession Number
PMID: 23673919
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s11356-013-1716-8 [doi]
Output Language
Unknown(0)
PMID
23673919
Abstract
Prior investigations identified an association between low-level blood arsenic (As) and bladder cancer risk among Tunisian men but questions remain regarding confounding by cadmium (Cd), a well-established bladder carcinogen. A case-control study of Tunisian men was re-examined to assess the levels of cadmium in blood and reparse the association between the simultaneous exposure to these metals and bladder cancer risk. Levels of blood Cd were significantly twice higher among cases than in controls (P0.67 mug/L), it was reduced to 2.10 (CI, 1.06-4.17). Adjustment for Cd exposure did not alter the risk associated to As exposure. This study is the first to report the relationship between Cd exposure and risk of bladder cancer occurrence in interaction with smoking and As exposure. Smoking is shown to be the main exposure source to Cd in the Tunisian population but also environmental pollution seems to be responsible of Cd exposure among non-smokers. Exposure assessment studies encompassing a wider population are needed.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Feki-Tounsi,M., Olmedo,P., Gil,F., Khlifi,R., Mhiri,M.N., Rebai,A., Hamza-Chaffai,A.
Original/Translated Title
URL
Date of Electronic
20130515
PMCID
Editors
Physical activity, obesity and gastroesophageal reflux disease in the general population 2012 Unit of Upper Gastrointestinal Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden. therese.djarv@ki.se
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
World journal of gastroenterology
Periodical, Abbrev.
World J.Gastroenterol.
Pub Date Free Form
28-Jul
Volume
18
Issue
28
Start Page
3710
Other Pages
3714
Notes
LR: 20151119; JID: 100883448; OID: NLM: PMC3406423; OTO: NOTNLM; 2012/02/07 [received]; 2012/05/11 [revised]; 2012/05/26 [accepted]; ppublish
Place of Publication
China
ISSN/ISBN
2219-2840; 1007-9327
Accession Number
PMID: 22851863
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.3748/wjg.v18.i28.3710 [doi]
Output Language
Unknown(0)
PMID
22851863
Abstract
AIM: To clarify the association between physical activity and gastroesophageal reflux disease (GERD) in non-obese and obese people. METHODS: A Swedish population-based cross-sectional survey was conducted. Participants aged 40-79 years were randomly selected from the Swedish Registry of the Total Population. Data on physical activity, GERD, body mass index (BMI) and the covariates age, gender, comorbidity, education, sleeping problems, and tobacco smoking were obtained using validated questionnaires. GERD was self-reported and defined as heartburn or regurgitation at least once weekly, and having at least moderate problems from such symptoms. Frequency of physical activity was categorized into three groups: (1) "high" (several times/week); (2) "intermediate" (approximately once weekly); and (3) "low" (1-3 times/mo or less). Analyses were stratified for participants with "normal weight" (BMI 30 kg/m(2)). Multivariate logistic regression was used to calculate odds ratios (ORs) with 95% confidence intervals (CIs), adjusted for potential confounding by covariates. RESULTS: Of 6969 eligible and randomly selected individuals, 4910 (70.5%) participated. High frequency of physical activity was reported by 2463 (50%) participants, GERD was identified in 472 (10%) participants, and obesity was found in 680 (14%). There were 226 (5%) individuals with missing information about BMI. Normal weight, overweight and obese participants were similar regarding distribution of gender and tobacco smoking status, while obese participants were on average slightly older, had fewer years of education, more comorbidity, slightly more sleeping problems, lower frequency of physical activity, and higher occurrence of GERD. Among the 2146 normal-weight participants, crude point estimates indicated a decreased risk of GERD among individuals with high frequency of physical activity (OR: 0.59, 95% CI: 0.39-0.89), compared to low frequency of physical activity. However, after adjustment for potential confounding factors, neither intermediate (OR: 1.30, 95% CI: 0.75-2.26) nor high (OR: 0.99, 95% CI: 0.62-1.60) frequency of physical activity was followed by decreased risk of GERD. Sleeping problems and high comorbidity were identified as potential confounders. Among the 1859 overweight participants, crude point estimates indicated no increased or decreased risk of GERD among individuals with intermediate or high frequency of physical activity, compared to low frequency. After adjustment for confounding, neither intermediate (OR: 0.75, 95% CI: 0.46-1.22) nor high frequency of physical activity were followed by increased or decreased risk of GERD compared to low frequency among nonobese participants. Sleeping problems and high comorbidity were identified as potential confounders for overweight participants. In obese individuals, crude ORs were similar to the adjusted ORs and no particular confounding factors were identified. Intermediate frequency of physical activity was associated with a decreased occurrence of GERD compared to low frequency of physical activity (adjusted OR: 0.41, 95% CI: 0.22-0.77). CONCLUSION: Intermediate frequency of physical activity might decrease the risk of GERD among obese individuals, while no influence of physical activity on GERD was found in non-obese people.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Djarv,T., Wikman,A., Nordenstedt,H., Johar,A., Lagergren,J., Lagergren,P.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC3406423
Editors
A comparison between indoor air quality before and after the implementation of the smoking ban in public places in Italy 2006 Unita funzionale per la prevenzione dei danni da fumo dell'istituto nazionale per lo studio e la cura dei tumori SIMG, Societa italiana di medicina generate, Milano.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Epidemiologia e prevenzione
Periodical, Abbrev.
Epidemiol.Prev.
Pub Date Free Form
Nov-Dec
Volume
30
Issue
6
Start Page
334
Other Pages
337
Notes
JID: 8902507; 0 (Tobacco Smoke Pollution); ppublish
Place of Publication
Italy
ISSN/ISBN
1120-9763; 1120-9763
Accession Number
PMID: 17333687
Language
ita
SubFile
Comparative Study; English Abstract; Journal Article; IM
DOI
2006/E&P6/E&P6_334_art2.pdf [pii]
Output Language
Unknown(0)
PMID
17333687
Abstract
OBJECTIVE: To monitor indoor air quality index in a few Italian hospitality industry venues before and after the implementation of the smoking ban in January 2005. DESIGN: Indoor PM2.5 measurements were carried out in four Milan restaurants during evening hours in the period January-February 2004, and again in January-February 2005, with concurrent outdoor PM2.5 monitoring. The measures were recorded with a portable laser-operated aerosol analyzer with a sampling time of 2 minutes, calibrated by comparison with gravimetric method RESULTS: PM2.5 ranged between 187+/-52 and 709+/-180 mg/m3, and between 24+/-10 e 141+/-28 mg/m3 (p <0.0001) in the years 2004 and 2005, respectively. After the 2005 smoking ban, overall indoor fine particle pollution decreased by values in the range from 81 to 96%. CONCLUSIONS: Within the limits of a small sample, the study showed a good compliance with the smoking ban in the hospitality industry which resulted in a remarkable improvement in air quality index. Smoking ban thus appears to achieve the aims of protecting people from exposure to an unwanted dangerous pollutant such as environmental tobacco smoke.
Descriptors
Air Pollution, Indoor/analysis/legislation & jurisprudence/prevention & control, Humans, Italy, Occupational Exposure/analysis, Public Facilities/legislation & jurisprudence, Tobacco Smoke Pollution/analysis/legislation & jurisprudence/prevention & control
Links
Book Title
Database
Publisher
Data Source
Authors
Ruprecht,A., Boffi,R., Mazza,R., Rossetti,E., De Marco,C., Invernizzi,G.
Original/Translated Title
Un confronto tra la qualita dell&#39;aria nei luoghi pubblici prima e dopo l&#39;introduzione della legge sull fumo passivo in Italia
URL
Date of Electronic
PMCID
Editors
Therapies against murine Candida guilliermondii infection, relationship between in vitro antifungal pharmacodynamics and outcome 2015 Unitat de Microbiologia, Facultat de Medicina i Ciencies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Tarragona, Spain.; Unitat de Microbiologia, Facultat de Medicina i Ciencies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Tarragona,
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Revista Iberoamericana De Micologia
Periodical, Abbrev.
Rev.Iberoam.Micol.
Pub Date Free Form
Jan-Mar
Volume
32
Issue
1
Start Page
34
Other Pages
39
Notes
CI: Copyright (c) 2013; JID: 9425531; 0 (Antifungal Agents); 0 (Echinocandins); 0 (liposomal amphotericin B); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); 9HLM53094I (anidulafungin); OTO: NOTNLM; 2013/07/11 [received]; 2013/10/09 [revised]; 2013
Place of Publication
Spain
ISSN/ISBN
2173-9188; 1130-1406
Accession Number
PMID: 24594291
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.riam.2013.10.008 [doi]
Output Language
Unknown(0)
PMID
24594291
Abstract
BACKGROUND: Candida guilliermondii has been recognized as an emerging pathogen showing a decreased susceptibility to fluconazole and considerably high echinocandin MICs. AIMS: Evaluate the in vitro activity of anidulafungin in comparison to amphotericin B and fluconazole against different isolates of C. guilliermondii, and their efficacy in an immunosuppressed murine model of disseminated infection. METHODS: The in vitro susceptibility of four strains against amphotericin B, fluconazole and anidulafungin was performed by using a reference broth microdilution method and time-kill curves. The in vivo efficacy was evaluated by determination of fungal load reduction in kidneys of infected animals receiving deoxycholate AMB at 0,8 mg/kg i.v., liposomal amphotericin B at 10 mg/kg i.v., fluconazole at 50 mg/kg, or anidulafungin at 10 mg/kg. RESULTS: Amphotericin B and anidulafungin showed fungicidal activity, while fluconazole was fungistatic for all the strains. In the murine model, liposomal amphotericin B at 10 mg/kg/day was effective in reducing the tissue burden in kidneys of mice infected with any of the tested strains. However, amphotericin B, anidulafungin and fluconazole were only effective against those strains showing low MIC values. CONCLUSIONS: Liposomal amphotericin B showed the higher activity and efficacy against the two strains of C. guilliermondii, in contrast to the poor effect of fluconazole and anidulafungin. Further studies with more isolates of C. guilliermondii representing a wider range of MICs should be carried out to assess whether there is any relationship between MIC values and anidulafungin efficacy.
Descriptors
Links
Book Title
Database
Publisher
Revista Iberoamericana de Micologia. Published by Elsevier Espana
Data Source
Authors
Paredes,K., Pastor,F.J., Capilla,J., Sutton,D.A., Mayayo,E., Fothergill,A.W., Guarro,J.
Original/Translated Title
URL
Date of Electronic
20140301
PMCID
Editors
Interaction of Candida albicans biofilms with antifungals: transcriptional response and binding of antifungals to beta-glucans 2010 Unite Biologie et Pathogenicite Fongiques, Institut Pasteur, Paris, France.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
May
Volume
54
Issue
5
Start Page
2096
Other Pages
2111
Notes
LR: 20141204; JID: 0315061; 0 (ALS3 protein, Candida albicans); 0 (Antifungal Agents); 0 (Echinocandins); 0 (Extracellular Matrix Proteins); 0 (Fungal Proteins); 0 (HWP1 protein, Candida albicans); 0 (Membrane Glycoproteins); 0 (beta-Glucans); 7XU7A7DROE
Place of Publication
United States
ISSN/ISBN
1098-6596; 0066-4804
Accession Number
PMID: 20194705
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1128/AAC.01638-09 [doi]
Output Language
Unknown(0)
PMID
20194705
Abstract
Candida albicans can form biofilms that exhibit elevated intrinsic resistance to various antifungal agents, in particular azoles and polyenes. The molecular mechanisms involved in the antifungal resistance of biofilms remain poorly understood. We have used transcript profiling to explore the early transcriptional responses of mature C. albicans biofilms exposed to various antifungal agents. Mature C. albicans biofilms grown under continuous flow were exposed for as long as 2 h to concentrations of fluconazole (FLU), amphotericin B (AMB), and caspofungin (CAS) that, while lethal for planktonic cells, were not lethal for biofilms. Interestingly, FLU-exposed biofilms showed no significant changes in gene expression over the course of the experiment. In AMB-exposed biofilms, 2.7% of the genes showed altered expression, while in CAS-exposed biofilms, 13.0% of the genes had their expression modified. In particular, exposure to CAS resulted in the upregulation of hypha-specific genes known to play a role in biofilm formation, such as ALS3 and HWP1. There was little overlap between AMB- or CAS-responsive genes in biofilms and those that have been identified as AMB, FLU, or CAS responsive in C. albicans planktonic cultures. These results suggested that the resistance of C. albicans biofilms to azoles or polyenes was due not to the activation of specific mechanisms in response to exposure to these antifungals but rather to the intrinsic properties of the mature biofilms. In this regard, our study led us to observe that AMB physically bound C. albicans biofilms and beta-glucans, which have been proposed to be major constituents of the biofilm extracellular matrix and to prevent azoles from reaching biofilm cells. Thus, enhanced extracellular matrix or beta-glucan synthesis during biofilm growth might prevent antifungals, such as azoles and polyenes, from reaching biofilm cells, thus limiting their toxicity to these cells and the associated transcriptional responses.
Descriptors
Amphotericin B/metabolism/pharmacology, Antifungal Agents/metabolism/pharmacology, Biofilms/drug effects/growth & development, Candida albicans/drug effects/genetics/growth & development, Drug Resistance, Fungal/physiology, Echinocandins/metabolism/pharmacology, Extracellular Matrix Proteins/metabolism, Fluconazole/metabolism/pharmacology, Fungal Proteins/genetics, Gene Expression Profiling, Gene Expression Regulation, Fungal/drug effects, Luciferases/genetics, Membrane Glycoproteins/genetics, Transcription, Genetic/drug effects, beta-Glucans/metabolism
Links
Book Title
Database
Publisher
Data Source
Authors
Vediyappan,G., Rossignol,T., d'Enfert,C.
Original/Translated Title
URL
Date of Electronic
20100301
PMCID
PMC2863626
Editors
Juvenile nitrogen uptake capacities and root architecture of two open-pollinated families of Picea abies. Effects of nitrogen source and ectomycorrhizal symbiosis 2003 Unite Mixte de Recherches Sol et Environnement, Equipe Rhizosphere & Symbioses, Institut National de la Recherche Agronomique, 2 Place Viala, 34060 Montpellier, France.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of Plant Physiology
Periodical, Abbrev.
J.Plant Physiol.
Pub Date Free Form
Oct
Volume
160
Issue
10
Start Page
1211
Other Pages
1218
Notes
LR: 20151119; JID: 9882059; 0 (Amino Acids); 0 (Nitrates); 0 (Quaternary Ammonium Compounds); N762921K75 (Nitrogen); ppublish
Place of Publication
Germany
ISSN/ISBN
0176-1617; 0176-1617
Accession Number
PMID: 14610890
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
S0176-1617(04)70512-X [pii]
Output Language
Unknown(0)
PMID
14610890
Abstract
This study was carried out to find early physiological differences occurring in young seedlings between two contrasting Picea abies open-pollinated families (OPF), one with high- and one with low-growth performance in the field by, determining their N uptake capacities and their root architecture. We used three potential N-sources in forest soil solution, NO3-, NH4+ and amino acids, to establish N uptake rates by the plants, whether or not associated with a fungus isolated from the field and identified as Paxillus involutus. NO3- fluxes were determined locally at the root surface using NO3(-)-selective microelectrodes whereas NH4+ and amino acid (L-glutamate and L-aspartate) uptake rates were calculated from their depletion of the incubation solution by the whole root system. Root systems were digitised in order to determine the number and the length of different root types. In non-mycorrhizal plants, the results showed that the most distinguishing parameters between OPF were NO3- uptake rates measured in the white tip of the secondary roots and the root architecture, with higher values determined in high-growth than in low-growth field performance OPF. The presence of the mycorrhizal fungus decreased NO3- uptake rates in both OPF and had an opposite effect on root architecture by increasing it in low-growth and decreasing it in high-growth field performance OPF, respectively. In non-mycorrhizal plants, NH4+ and amino-acid uptake rates were not different between OPF. Mycorrhizal symbiosis did not change NH4+ uptake rates whereas it increased that of amino acids, specifically that of L-aspartate in the low-growth field performance OPF. Taken together these results suggest that the measurement of local fluxes in roots of young plants could be a good potential tool for the early evaluating of growth capacity of Picea abies OPF.
Descriptors
Amino Acids/metabolism, Biological Transport, Active, Mycorrhizae/metabolism, Nitrates/metabolism, Nitrogen/metabolism, Picea/growth & development/metabolism/microbiology, Plant Roots/anatomy & histology/metabolism/microbiology, Quaternary Ammonium Compounds/metabolism, Seedlings/metabolism/microbiology, Symbiosis
Links
Book Title
Database
Publisher
Data Source
Authors
Boukcim,H., Plassard,C.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A discrete-event simulation of smoking-cessation strategies based on varenicline pivotal trial data 2011 United BioSource Corporation, Lexington, Massachusetts, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PharmacoEconomics
Periodical, Abbrev.
Pharmacoeconomics
Pub Date Free Form
Jun
Volume
29
Issue
6
Start Page
497
Other Pages
510
Notes
LR: 20151119; JID: 9212404; 0 (Benzazepines); 0 (Nicotinic Agonists); 0 (Quinoxalines); W6HS99O8ZO (Varenicline); ppublish
Place of Publication
New Zealand
ISSN/ISBN
1179-2027; 1170-7690
Accession Number
PMID: 21452908
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; T
DOI
10.2165/11589230-000000000-00000 [doi]
Output Language
Unknown(0)
PMID
21452908
Abstract
BACKGROUND: Smoking is the leading cause of preventable death in the US. While one in five individuals smoke, and 70% of these indicate a desire to quit,
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Xenakis,J.G., Kinter,E.T., Ishak,K.J., Ward,A.J., Marton,J.P., Willke,R.J., Davies,S., Caro,J.J.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors