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Contraceptive service needs of women with young children presenting for pediatric care 2015 Department of Pediatrics, Johns Hopkins University School of Medicine, 200 N. Wolfe Street, Baltimore, MD 21287, USA; Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Contraception
Periodical, Abbrev.
Contraception
Pub Date Free Form
Nov
Volume
92
Issue
5
Start Page
508
Other Pages
512
Notes
LR: 20160326; CI: Copyright (c) 2015; GR: P20 MD000198/MD/NIMHD NIH HHS/United States; GR: P20 MD000198/MD/NIMHD NIH HHS/United States; JID: 0234361; NIHMS715366; OID: NLM: NIHMS715366 [Available on 11/01/16]; OID: NLM: PMC4807654 [Available on 11/01/16];
Place of Publication
United States
ISSN/ISBN
1879-0518; 0010-7824
Accession Number
PMID: 26197265
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.contraception.2015.07.004 [doi]
Output Language
Unknown(0)
PMID
26197265
Abstract
OBJECTIVES: The primary objective of this study is to characterize the need for contraceptive services and contraceptive method use among women with young children presenting to child health clinics. A secondary objective is to characterize the factors, including access to care and health needs, that exist in this population and to evaluate their association with contraceptive method use. STUDY DESIGN: This is a cross-sectional study of women with children under age 36 months presenting to four child health practices in the Baltimore, Maryland, area. Participating women completed a survey to assess desire for pregnancy, contraceptive method use and related characteristics. RESULTS: A total of 238 participants (82%) were in need of contraceptive services (fertile and not desiring pregnancy). Overall, 59 (25%) of women in need were not using a contraceptive method (unmet need) and 79 (33%) were using a highly effective method (implant or intrauterine device). Factors associated with lower odds of unmet need for contraceptive services included attendance at a routine postpartum visit and visiting a healthcare provider to discuss contraception after pregnancy. Approximately half of index pregnancies were unintended and this was the only health factor associated with greater odds of using of a highly effective contraceptive method. CONCLUSIONS: Most women presenting with young children for pediatric care indicated that they were not currently trying to become pregnant and reported current methods of pregnancy prevention that ranged from none to highly effective. Women who had not sought postpregnancy contraceptive care were more likely to have unmet need for contraceptive services. IMPLICATIONS: Child health clinics may be a novel site for providing contraceptive care to women with children as part of a strategy to reduce unplanned pregnancies.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Upadhya,K.K., Burke,A.E., Marcell,A.V., Mistry,K., Cheng,T.L.
Original/Translated Title
URL
Date of Electronic
20150718
PMCID
PMC4807654
Editors
Hookah use among adolescents in the United States: results of a national survey 2014 Department of Pediatrics, New York University School of Medicine, New York, NY;
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
16
Issue
2
Start Page
231
Other Pages
237
Notes
JID: 9815751; 2013/10/23 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 24154512
Language
eng
SubFile
Journal Article; IM
DOI
10.1093/ntr/ntt160 [doi]
Output Language
Unknown(0)
PMID
24154512
Abstract
INTRODUCTION: U.S. adolescents increasingly use alternative tobacco products (ATPs), including hookah. No study has previously assessed correlates of adolescent hookah use in a nationally representative sample. METHODS: Cross-sectional, nationally representative data of adolescents from the 2011 National Youth Tobacco Survey (NYTS) were used. Student demographics and their use of, exposure to, and beliefs about tobacco were examined as correlates of hookah use. RESULTS: Of adolescents nationwide, 7.3% reported ever trying hookah and 2.6% reported using hookah within the past month. Increasing age was associated with trying hookah, but not current hookah use. Sex was unassociated with hookah use. Asians were most likely to have tried hookah; Hispanics and those of another race reported greater current hookah use. Hookah use increased with perceived ease of access to and willingness to try tobacco. Students with a hookah user at home were more likely to have tried hookah and to currently use hookah. Current cigarette use was not associated with current hookah use (odds ratio [OR] = 1.3, 95% CI = 0.8-2.1), but was associated with trying hookah (OR = 1.5, 95% CI = 1.1-2.2). Non-cigarette tobacco use was associated with trying hookah (OR = 2.7, 95% CI = 2.1-3.5) and current hookah use (OR = 4.8, 95% CI = 2.7-8.7). CONCLUSIONS: A sizeable minority of U.S. adolescents use hookah, particularly those living with hookah users, those who use other ATPs, and those who perceive tobacco as easily accessible. Current cigarette use was not associated with current hookah use. Future studies assessing the dangers of hookah use and interventions to curb this emerging problem appear warranted.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Amrock,S.M., Gordon,T., Zelikoff,J.T., Weitzman,M.
Original/Translated Title
URL
Date of Electronic
20131023
PMCID
Editors
Perception of e-cigarette harm and its correlation with use among U.S. adolescents 2015 Department of Pediatrics, New York University School of Medicine, New York, NY; stephen.amrock@med.nyu.edu.; Department of Pediatrics, New York University School of Medicine, New York, NY;; Department of Pediatrics, New York University School of Medicine,
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Mar
Volume
17
Issue
3
Start Page
330
Other Pages
336
Notes
CI: (c) The Author 2014; JID: 9815751; 2014/08/14 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25125321
Language
eng
SubFile
Journal Article; IM
DOI
10.1093/ntr/ntu156 [doi]
Output Language
Unknown(0)
PMID
25125321
Abstract
INTRODUCTION: U.S. adolescents increasingly use e-cigarettes. The perceived harm of e-cigarettes has not been described, nor has the correlation between harm perception and e-cigarette use been assessed. This study examines correlates of e-cigarette harm perception and use of e-cigarettes in a national survey. METHODS: We used cross-sectional nationally representative data from the 2012 National Youth Tobacco Survey (n = 24,658). Cross-tabulations and multivariate ordered probit and logistic regression models were employed to assess relative harm perception and e-cigarette use. RESULTS: Half of U.S. adolescents had heard of e-cigarettes. Of these, 13.2% (95% confidence interval [CI] = 11.7-14.9) and 4.0% (95% CI = 3.4-4.7) reported ever or currently using e-cigarettes, respectively. Of those aware of e-cigarettes, 34.2% (95% CI = 32.8-35.6) believed e-cigarettes were less harmful than cigarettes. Among those trying e-cigarettes, 71.8% (95% CI = 69.0-74.5) believed e-cigarettes were comparatively less harmful. Females and those >/= 17 years old were more likely to perceive e-cigarettes as more harmful relative to cigarettes, while on average Whites, users of other tobacco products, and those with family members who used tobacco were more likely to perceive e-cigarettes as comparatively safer. Among cigarette-naive e-cigarette users, use of other tobacco products and perceived harm reduction by e-cigarettes were, respectively, on average associated with 1.6 and 4.1 percentage-point increases in e-cigarette use. CONCLUSIONS: Perception of e-cigarettes as less harmful than conventional cigarettes was associated with increased e-cigarette use, including among cigarette-naive e-cigarette users. These findings should prompt further scientific investigation and merit attention from regulators.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Amrock,S.M., Zakhar,J., Zhou,S., Weitzman,M.
Original/Translated Title
URL
Date of Electronic
20140814
PMCID
Editors
Effects of hookah smoking on indoor air quality in homes 2016 Department of Pediatrics, New York University, School of Medicine, New York, New York, USA.; College of Global Public Health, New York University, New York, New York, USA.; Department of Environmental Medicine, New York University, School of Med(TRUNCATED
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Sep
Volume
26
Issue
5
Start Page
586
Other Pages
591
Notes
LR: 20181202; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.; GR: K24 DA038345/DA/NIDA NIH HHS/United St
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 27798320
Language
eng
SubFile
Journal Article; IM
DOI
10.1136/tobaccocontrol-2016-053165 [doi]
Output Language
Unknown(0)
PMID
27798320
Abstract
INTRODUCTION: Hookahs (water pipes) are rapidly increasing in popularity worldwide. Evidence suggests that although perceived as safer than cigarette smoke, hookah smoke may be as, or even more, dangerous as cigarette smoke. METHODS: Air samples from 33 homes-11 where only hookah-smoking occurred, 12 with only cigarettes and 10 with no smoking-were collected to analyse concentrations of particulate matter (PM2.5), black carbon, elemental and organic carbon and carbon monoxide (CO). Air quality was assessed in rooms where smoking occurred and in an adjacent room. RESULTS: Hookah and cigarette smoking impaired home air quality. The rooms in which hookahs were smoked showed the highest concentrations for all pollutants. CO was significantly greater in the rooms where hookahs were smoked than in the cigarette-smoking rooms and the non-smoking households (p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Weitzman,M., Yusufali,A.H., Bali,F., Vilcassim,M.J.R., Gandhi,S., Peltier,R., Nadas,A., Sherman,S., Lee,L., Hong,Z., Shearston,J., Park,S.H., Gordon,T.
Original/Translated Title
URL
Date of Electronic
20161026
PMCID
PMC5505800
Editors
Predictors of smoking cessation in adolescents 1998 Department of Pediatrics, Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, NH, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Archives of Pediatrics & Adolescent Medicine
Periodical, Abbrev.
Arch.Pediatr.Adolesc.Med.
Pub Date Free Form
Apr
Volume
152
Issue
4
Start Page
388
Other Pages
393
Notes
LR: 20071114; GR: CA-23108/CA/NCI NIH HHS/United States; GR: DA 04100/DA/NIDA NIH HHS/United States; JID: 9422751; ppublish
Place of Publication
UNITED STATES
ISSN/ISBN
1072-4710; 1072-4710
Accession Number
PMID: 9559717
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; AIM; IM
DOI
Output Language
Unknown(0)
PMID
9559717
Abstract
OBJECTIVE: To examine factors associated with cessation of smoking in adolescents 12 to 18 years of age who smoke cigarettes. DESIGN AND SETTING: Prospective school-based cohort study of 1384 New Hampshire high school students surveyed at baseline and annually up to 3 subsequent years regarding their substance abuse behaviors, including adolescents who smoked 1 or more cigarettes within the past 30 days at baseline. OUTCOME MEASURES: Cessation behavior was defined by a subsequent response indicating nonsmoking status. We examined associations between smoking cessation and baseline measurements of the level of addiction (cigarette consumption pattern), experience with quitting, intent to quit now and in the future, opinion of adults smoking more than 1 pack of cigarettes per day, social influences to smoke, sex, and psychological attributes. RESULTS: Of 276 adolescents who qualified as cigarette smokers at baseline, 123 (44.6%) were occasional smokers, 65 (23.6%) were daily smokers of 1 to 9 cigarettes, and 88 (31.9%) were daily smokers of 10 or more cigarettes. While 39 (14.1%) had smoked for 1 year or less, 62 (22.5%) had smoked for 6 or more years. Seventy-five (27.2%) reported failed past attempts to quit smoking, 71 (25.7%) reported wanting to quit now, and 50 (18.1%) reported definitely intending to be a nonsmoker in the future. Seventy-nine smokers (28.6%) described themselves as nonsmokers in follow-up surveys. The smoking cessation rate was 46.3% among occasional smokers, 12.3% among daily smokers of 1 to 9 cigarettes, and 6.8% among daily smokers of 10 or more cigarettes. Smoking cessation was associated with occasional smoking status (adjusted odds ratio 6.67 compared with daily smokers of 10 or more cigarettes [95% confidence intervals, 2.26-19.69]), and definite intentions to quit in the future (2.67 [95% confidence intervals, 1.2-5.7]). Most of those with definite intentions to quit in the future were occasional smokers (92.0%). CONCLUSIONS: This study documents cessation of smoking in nearly one third of the adolescent smokers. The cessation rate among daily smokers of 10 or more cigarettes per day is comparable with adult cessation rates. Adolescents who are less addicted, measured by low frequency of cigarette use, are more likely than daily users to quit. In addition, definite intent to quit in the future predicts cessation, but only among occasional smokers. In contrast with adults, experience with quitting was not associated with a higher likelihood of cessation. Pediatricians should focus on keeping occasional smokers from moving into daily smoking status, where nicotine addiction begins to play a prominent role in maintaining the behavior. Further study is needed to guide enhancement of the recruitment of adolescents into cessation, assessment of nicotine dependence in daily adolescent smokers, and appropriate use of nicotine replacement therapy in this group.
Descriptors
Adolescent, Adult, Child, Curriculum, Female, Follow-Up Studies, Health Education, Humans, Male, Outcome and Process Assessment (Health Care), Smoking/epidemiology/prevention & control, Smoking Cessation/statistics & numerical data
Links
Book Title
Database
Publisher
Data Source
Authors
Sargent,J. D., Mott,L. A., Stevens,M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Effect of cigarette promotions on smoking uptake among adolescents 2000 Department of Pediatrics, Norris Cotton Cancer Center, Dartmouth Medical School, New Hampshire, USA. James.D.Sargent@Hitchcock.org
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Preventive medicine
Periodical, Abbrev.
Prev.Med.
Pub Date Free Form
Apr
Volume
30
Issue
4
Start Page
320
Other Pages
327
Notes
LR: 20130705; CI: Copyright 2000; GR: CA-23108/CA/NCI NIH HHS/United States; GR: CA-67538/CA/NCI NIH HHS/United States; GR: P30 CA023108/CA/NCI NIH HHS/United States; JID: 0322116; CIN: Prev Med. 2001 Nov;33(5):514-5. PMID: 11676594; ppublish
Place of Publication
UNITED STATES
ISSN/ISBN
0091-7435; 0091-7435
Accession Number
PMID: 10731461
Language
eng
SubFile
Journal Article; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1006/pmed.1999.0629 [doi]
Output Language
Unknown(0)
PMID
10731461
Abstract
BACKGROUND: The purpose of this study was to evaluate the association between receptivity to cigarette promotions and smoking uptake in a cohort of adolescents. METHODS AND MEASURES: This was a prospective cohort study of 480 4th- to 11th-grade students conducted in three rural Vermont K-12 schools. Cigarette use was determined by self-report at baseline, 12 months (survey 2), and 21 months (survey 3). Proportional odds models were used to evaluate smoking uptake as a function of baseline measures of cigarette use, receptivity to cigarette promotions, and confounding factors, including grade, parental education, peer smoking, and family smoking. Adolescents were receptive to cigarette promotions if they owned or were willing to use a personal item bearing a cigarette brand logo [cigarette promotional item (CPI)]. Smoking status was measured using a 6-point ordinal index that combined experience and attitudes: 0 = never smoker/not susceptible to smoking, 1 = never smoker/susceptible to smoking, 2 = puffer (1 cigarette or less in lifetime), 3 = non-current experimenter (2-99 cigarettes in lifetime/none in past 30 days), 4 = current experimenter, and 5 = smoker (> or =100 cigarettes in lifetime). RESULTS: The 480 students were equally distributed across grade at baseline. Environmental exposure to smoking was high, and 30% were receptive to cigarette promotions at baseline. Higher levels on the smoking index at baseline were associated with higher grade in school, peer smoking, and receptivity to cigarette promotions. One hundred eighty-five students (38.5%) had moved to a higher category on the smoking index by survey 3, of whom 30 had become smokers. Receptivity to cigarette promotions at baseline was significantly associated with higher smoking uptake, with 48.7% of receptive students moving up one or more categories on the smoking index [adjusted proportional odds 1.9 (95% CI 1.3, 2.9)]. Acquisition of receptivity to cigarette promotions was also associated with increased smoking uptake, with those becoming receptive in surveys 2 or 3 having significantly higher odds of progression [3.6 (1.8, 7.0) and 2.9 (1.5, 5.5), respectively] compared with those who did not change. Conversely, those who were receptive at one point but became non-receptive in surveys 2 or 3 had lower odds of progression [0.4 (0.2, 0.9) and 0.5 (0.3, 1.1), respectively]. CONCLUSIONS: This study supports a close linkage between tobacco promotional activities and uptake of smoking among adolescents beyond baseline descriptions of receptivity to cigarette promotions. Over time, the likelihood of smoking uptake is increased when an adolescent acquires a CPI or becomes willing to use one and is decreased when an adolescent who owns a CPI loses it or becomes unwilling to use it. This provides strong evidence that elimination of cigarette promotional campaigns could reduce adolescent smoking.
Descriptors
Adolescent, Adolescent Behavior, Advertising as Topic, Cohort Studies, Data Collection, Female, Humans, Incidence, Male, New Hampshire/epidemiology, Odds Ratio, Plants, Toxic, Prospective Studies, Reproducibility of Results, Sex Distribution, Smoking/epidemiology, Tobacco
Links
Book Title
Database
Publisher
American Health Foundation and Academic Press
Data Source
Authors
Sargent,J. D., Dalton,M., Beach,M., Bernhardt,A., Heatherton,T., Stevens,M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Short and long term health effects of parental tobacco smoking during pregnancy and lactation: a descriptive review 2015 Department of Pediatrics, San Paolo Hospital, Via A Di Rudini 8, 20142, Milan, Italy. giuseppe.banderali@unimi.it.; Department of Health Sciences, University of Milan, Via A Di Rudini 8, 20142, Milan, Italy. giuseppe.banderali@unimi.it.; U.O.C. Pediatria
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of translational medicine
Periodical, Abbrev.
J.Transl.Med.
Pub Date Free Form
15-Oct
Volume
13
Issue
Start Page
327
Other Pages
015-0690-y
Notes
LR: 20151018; JID: 101190741; 0 (Tobacco Smoke Pollution); OID: NLM: PMC4608184; 2015/06/22 [received]; 2015/10/07 [accepted]; 2015/10/15 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1479-5876; 1479-5876
Accession Number
PMID: 26472248
Language
eng
SubFile
Journal Article; Review; IM
DOI
10.1186/s12967-015-0690-y [doi]
Output Language
Unknown(0)
PMID
26472248
Abstract
A great deal of attention has been focused on adverse effects of tobacco smoking on conception, pregnancy, fetal, and child health. The aim of this paper is to discuss the current evidence regarding short and long-term health effects on child health of parental smoking during pregnancy and lactation and the potential underlying mechanisms. Studies were searched on MEDLINE((R)) and Cochrane database inserting, individually and using the Boolean ANDs and ORs, 'pregnancy', 'human lactation', 'fetal growth', 'metabolic outcomes', 'obesity', 'cardiovascular outcomes', 'blood pressure', 'brain development', 'respiratory outcomes', 'maternal or paternal or parental tobacco smoking', 'nicotine'. Publications coming from the reference list of studies were also considered from MEDLINE. All sources were retrieved between 2015-01-03 and 2015-31-05. There is overall consistency in literature about negative effects of fetal and postnatal exposure to parental tobacco smoking on several outcomes: preterm birth, fetal growth restriction, low birth weight, sudden infant death syndrome, neurodevelopmental and behavioral problems, obesity, hypertension, type 2 diabetes, impaired lung function, asthma and wheezing. While maternal smoking during pregnancy plays a major role on adverse postnatal outcomes, it may also cumulate negatively with smoking during lactation and with second-hand smoking exposure. Although this review was not strictly designed as a systematic review and the PRISMA Statement was not fully applied it may benefit the reader with a promptly and friendly readable update of the matter. This review strengthens the need to plan population health policies aimed to implement educational programs to hopefully minimize tobacco smoke exposure during pregnancy and lactation.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Banderali,G., Martelli,A., Landi,M., Moretti,F., Betti,F., Radaelli,G., Lassandro,C., Verduci,E.
Original/Translated Title
URL
Date of Electronic
20151015
PMCID
PMC4608184
Editors
Self-reported prevalence and risk factors of asthma among Korean adolescents: 5-year follow-up study, 1995-2000 2004 Department of Pediatrics, Ulsan University, Seoul, Korea.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Periodical, Abbrev.
Clin.Exp.Allergy
Pub Date Free Form
Oct
Volume
34
Issue
10
Start Page
1556
Other Pages
1562
Notes
LR: 20151119; JID: 8906443; 0 (Tobacco Smoke Pollution); ppublish
Place of Publication
England
ISSN/ISBN
0954-7894; 0954-7894
Accession Number
PMID: 15479270
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
CEA2084 [pii]
Output Language
Unknown(0)
PMID
15479270
Abstract
OBJECTIVES: The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires have shown that the prevalence of childhood asthma is increasing worldwide. Although Asian countries used to have lower prevalence rates of allergic disease than Western countries, this prevalence is increasing in several Asian countries. To determine whether the prevalence of childhood asthma is changing in Korean adolescents, we compared findings from nationwide cross-sectional surveys in 1995 and 2000 on populations of middle-school children using the Korean version of the ISAAC questionnaire. METHODS: We developed Korean versions of the ISAAC written (WQ) and video (AVQ) questionnaires for allergic diseases. In 1995, the enrolled population consisted of 15,481 children, ages 12-15, and encompassing all three grades in middle school, selected from 34 schools across the nation; the response rate was 97.3%. In 2000, 15,894 children were selected from 31 of the same schools, and the response rate was 96.4%. The SAS system version 8.0 was utilized for all statistical analyses. RESULTS: The WQ showed that the lifetime and 12-month prevalence of wheeze did not change from 1995 to 2000. While the 12-month prevalence rates of sleep disturbed by wheezing and night cough increased, the rates of severe attack of wheezing and exercise-induced wheeze did not change, over this period of time. The lifetime prevalence of asthma diagnosis, however, increased significantly, from 2.7% in 1995 to 5.3% in 2000, as did the 12-month prevalence of asthma treatment, from 1.0% in 1995 to 1.9% in 2000. The AVQ also showed increases in the lifetime and 12-month prevalence rates of wheeze at rest, exercise-induced wheeze, nocturnal wheeze, nocturnal cough, and severe wheeze over this period of time. These were especially because of significant increases in the Provincial cities of Korea. Interestingly, the 12-month prevalence of wheeze was consistently high in Cheju with low air pollution indices, whereas this rate was low in Ulsan and Ansan with very high air pollution indices. Risk factor analysis showed that body mass index (BMI), passive smoking, and living with a dog or cat, but not air pollution, were associated with higher risk of wheeze. CONCLUSIONS: In the 5-year period from 1995 to 2000, the prevalence of asthma symptoms has increased in Korean adolescents, much of it because of increases in Provincial Centers. BMI, passive smoking, and living with a dog or cat are important risk factors. Environmental factors other than air pollution may be associated with increases in asthma, especially in Provincial Centers.
Descriptors
Adolescent, Age Distribution, Asthma/epidemiology/physiopathology, Body Mass Index, Body Weight/physiology, Child, Exercise/physiology, Female, Follow-Up Studies, Humans, Korea/epidemiology, Male, Prevalence, Respiratory Sounds/etiology, Risk Factors, Sex Distribution, Surveys and Questionnaires, Tobacco Smoke Pollution/adverse effects
Links
Book Title
Database
Publisher
Data Source
Authors
Hong,S. J., Lee,M. S., Sohn,M. H., Shim,J. Y., Han,Y. S., Park,K. S., Ahn,Y. M., Son,B. K., Lee,H. B., Korean ISAAC Study Group
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
From concept to application: the impact of a community-wide intervention to improve the delivery of preventive services to children 2001 Department of Pediatrics, University of North Carolina Children's Primary Care Research Group, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7226, USA. margolis@med.unc.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Pediatrics
Periodical, Abbrev.
Pediatrics
Pub Date Free Form
Sep
Volume
108
Issue
3
Start Page
E42
Other Pages
Notes
LR: 20151119; JID: 0376422; ppublish
Place of Publication
United States
ISSN/ISBN
1098-4275; 0031-4005
Accession Number
PMID: 11533360
Language
eng
SubFile
Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; AIM; IM
DOI
Output Language
Unknown(0)
PMID
11533360
Abstract
OBJECTIVE: To improve health outcomes of children, the US Maternal and Child Health Bureau has recommended more effective organization of preventive services within primary care practices and more coordination between practices and community-based agencies. However, applying these recommendations in communities is challenging because they require both more complex systems of care delivery within organizations and more complex interactions between them. To improve the way that preventive health care services are organized and delivered in 1 community, we designed, implemented, and assessed the impact of a health care system-level approach, which involved addressing multiple care delivery processes, at multiple levels in the community, the practice, and the family. Our objective was to improve the processes of preventive services delivery to all children in a defined geographic community, with particular attention to health outcomes for low-income mothers and infants. DESIGN: Observational intervention study in 1 North Carolina county (population 182 000) involving low- income pregnant mothers and their infants, primary care practices, and departments of health and mental health. An interrupted time-series design was used to assess rates of preventive services in office practices before and after the intervention, and a historical cohort design was used to compare maternal and child health outcomes for women enrolled in an intensive home visiting program with women who sought prenatal care during the 9 months before the program's initiation. Outcomes were assessed when the infants reached 12 months of age. INTERVENTIONS: Our primary objective was to achieve changes in the process of care delivery at the level of the clinical interaction between care providers and patients that would lead to improved health and developmental outcomes for families. We selected interventions that were directed toward major risk factors (eg, poverty, ineffective care systems for preventive care in office practices) and for which there was existing evidence of efficacy. The interventions involved community-, practice-, and family-level strategies to improve processes of care delivery to families and children. The objectives of the community-level intervention were: 1) to achieve policy level changes that would result in changes in resources available at the level of clinical care, 2) to engage multiple practice organizations in the intervention to achieve an effect on most, if not all, families in the community, and 3) to enhance communication between, among, and within public and private practice organizations to improve coordination and avoid duplication of services. The objective of the practice-level interventions was to overcome specific barriers in the process of care delivery so that preventive services could be effectively delivered. To assist the health department in implementing the family-level intervention, we provided assistance in hiring and training staff and ongoing consultation on staff supervision, including the use of structured protocols for care delivery, and regular feedback data about implementation of the program. Interventions with primary care practices focused on the design of the delivery system within the office and the use of teamwork and data in an "office systems" approach to improving clinical preventive care. All practices (N = 8) that enrolled at least 5 infants/month received help in assessing performance and developing systems (eg, preventive services flow sheets) for preventive services delivery. Family-level interventions addressed the process of care delivery to high-risk pregnant women (<100% poverty) and their infants. Mothers were recruited for the home visiting intervention when they first sought prenatal care at the community health center, the county's largest provider of prenatal care to underserved women. The home visiting intervention involved teams of nurses and educators and invo
Descriptors
Adult, Child Abuse/prevention & control, Child Health Services/organization & administration/standards, Community Networks/organization & administration, Female, Home Care Services/organization & administration, Humans, Immunization/statistics & numerical data, Infant, Infant, Newborn, Maternal-Child Health Centers/organization & administration, North Carolina, Outcome and Process Assessment (Health Care), Patient Education as Topic/organization & administration, Practice Patterns, Physicians'/standards, Pregnancy, Prenatal Care/organization & administration, Preventive Health Services/organization & administration/standards, Primary Health Care/organization & administration/standards, Quality Assurance, Health Care, Socioeconomic Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Margolis,P. A., Stevens,R., Bordley,W. C., Stuart,J., Harlan,C., Keyes-Elstein,L., Wisseh,S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A novel assay of biofilm antifungal activity reveals that amphotericin B and caspofungin lyse Candida albicans cells in biofilms 2011 Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Yeast (Chichester, England)
Periodical, Abbrev.
Yeast
Pub Date Free Form
Aug
Volume
28
Issue
8
Start Page
561
Other Pages
568
Notes
LR: 20131121; CI: Copyright (c) 2011; GR: 1R01AI075033/AI/NIAID NIH HHS/United States; JID: 8607637; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Fungal Proteins); 7XU7A7DROE (Amphotericin B); EC 2.7.4.3 (Adenylate Kinase); F0XDI6ZL63 (caspofungin); 2011/
Place of Publication
England
ISSN/ISBN
1097-0061; 0749-503X
Accession Number
PMID: 21674619
Language
eng
SubFile
Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; IM
DOI
10.1002/yea.1860 [doi]
Output Language
Unknown(0)
PMID
21674619
Abstract
The ability of Candida albicans to form drug-resistant biofilms is an important factor in its contribution to human disease. Assays to identify and characterize molecules with activity against fungal biofilms are crucial for the development of drugs with improved anti-biofilm activity. Here we report the application of an adenylate kinase (AK)-based cytotoxicity assay of fungal cell lysis to the characterization of agents active against C. albicans biofilms. We have developed three protocols for the AK assay. The first measures AK activity in the supernatants of biofilms treated with antifungal drugs and can be performed in parallel with a standard 2,3-bis-(2-methoxy-4-nitro-5-sulphophenyl)-2H-tetrazolium-5-caboxanilide-based biofilm susceptibility assay; a second, more sensitive protocol measures the AK activity present within the biofilm matrix; and a third procedure allows the direct visualization of lytic activity toward biofilms formed on catheter material. Amphotericin B and caspofungin, the two most effective anti-biofilm drugs currently used to treat fungal infections, both directly lyse planktonic C. albicans cells in vitro, leading to the release of AK into the culture medium. These studies serve to validate the AK-based lysis assay as a useful addition to the methods for the characterization of antifungal agents active toward biofilms and provide insights into the mode of action of amphotericin B and caspofungin against C. albicans biofilms.
Descriptors
Links
Book Title
Database
Publisher
John Wiley & Sons, Ltd
Data Source
Authors
DiDone,L., Oga,D., Krysan,D.J.
Original/Translated Title
URL
Date of Electronic
20110615
PMCID
Editors