WTS database

Title	Pub Year	Author Sort descending	SearchLink
Measurement of fine particles and smoking activity in a statewide survey of 36 California Indian casinos	2011	Department of Civil and Environmental Engineering, Stanford University, Stanford, California 94305, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of exposure science & environmental epidemiology Periodical, Abbrev. J.Expo.Sci.Environ.Epidemiol. Pub Date Free Form Jan-Feb Volume 21 Issue 1 Start Page 31 Other Pages 41 Notes LR: 20141204; JID: 101262796; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); OID: NLM: PMC3007589; 2010/02/17 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1559-064X; 1559-0631 Accession Number PMID: 20160761 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1038/jes.2009.75 [doi] Output Language Unknown(0) PMID 20160761 Abstract Despite California's 1994 statewide smoking ban, exposure to secondhand smoke (SHS) continues in California's Indian casinos. Few data are available on exposure to airborne fine particles (PM(2).(5)) in casinos, especially on a statewide basis. We sought to measure PM(2).(5) concentrations in Indian casinos widely distributed across California, exploring differences due to casino size, separation of smoking and non-smoking areas, and area smoker density. A selection of 36 out of the 58 Indian casinos throughout California were each visited for 1-3 h on weekend or holiday evenings, using two or more concealed monitors to measure PM(2).(5) concentrations every 10 s. For each casino, the physical dimensions and the number of patrons and smokers were estimated. As a preliminary assessment of representativeness, we also measured eight casinos in Reno, NV. The average PM(2).(5) concentration for the smoking slot machine areas (63 mug/m(3)) was nine times as high as outdoors (7 mug/m(3)), whereas casino non-smoking restaurants (29 mug/m(3)) were four times as high. Levels in non-smoking slot machine areas varied: complete physical separation reduced concentrations almost to outdoor levels, but two other separation types had mean levels that were 13 and 29 mug/m(3), respectively, higher than outdoors. Elevated PM(2).(5) concentrations in casinos can be attributed primarily to SHS. Average PM(2).(5) concentrations during 0.5-1 h visits to smoking areas exceeded 35 mug/m(3) for 90% of the casino visits. Descriptors Links Book Title Database Publisher Data Source Authors Jiang,R.T., Cheng,K.C., Acevedo-Bolton,V., Klepeis,N.E., Repace,J.L., Ott,W.R., Hildemann,L.M. Original/Translated Title URL Date of Electronic 20100217 PMCID PMC3007589 Editors
Spatial variability and application of ratios between BTEX in two Canadian cities	2011	Department of Civil and Environmental Engineering, University of Windsor, Windsor, ON, Canada N9B 3P4.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full TheScientificWorldJournal Periodical, Abbrev. ScientificWorldJournal Pub Date Free Form Volume 11 Issue Start Page 2536 Other Pages 2549 Notes LR: 20150128; JID: 101131163; 0 (Air Pollutants); 0 (Benzene Derivatives); 0 (Vehicle Emissions); 0 (Volatile Organic Compounds); 0 (Xylenes); 3FPU23BG52 (Toluene); J64922108F (Benzene); L5I45M5G0O (ethylbenzene); OID: NLM: PMC3253549; OTO: NOTNLM; 2011/1 Place of Publication England ISSN/ISBN 1537-744X; 1537-744X Accession Number PMID: 22235184 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1100/2011/167973 [doi] Output Language Unknown(0) PMID 22235184 Abstract Spatial monitoring campaigns of volatile organic compounds were carried out in two similarly sized urban industrial cities, Windsor and Sarnia, ON, Canada. For Windsor, data were obtained for all four seasons at approximately 50 sites in each season (winter, spring, summer, and fall) over a three-year period (2004, 2005, and 2006) for a total of 12 sampling sessions. Sampling in Sarnia took place at 37 monitoring sites in fall 2005. In both cities, passive sampling was done using 3M 3500 organic vapor samplers. This paper characterizes benzene, toluene, ethylbenzene, o, and (m + p)-xylene (BTEX) concentrations and relationships among BTEX species in the two cities during the fall sampling periods. BTEX concentration levels and rank order among the species were similar between the two cities. In Sarnia, the relationships between the BTEX species varied depending on location. Correlation analysis between land use and concentration ratios showed a strong influence from local industries. Use one of the ratios between the BTEX species to diagnose photochemical age may be biased due to point source emissions, for example, 53 tonnes of benzene and 86 tonnes of toluene in Sarnia. However, considering multiple ratios leads to better conclusions regarding photochemical aging. Ratios obtained in the sampling campaigns showed significant deviation from those obtained at central monitoring stations, with less difference in the (m + p)/E ratio but better overall agreement in Windsor than in Sarnia. Descriptors Links Book Title Database Publisher Data Source Authors Miller,L., Xu,X., Wheeler,A., Atari,D.O., Grgicak-Mannion,A., Luginaah,I. Original/Translated Title URL Date of Electronic 20111229 PMCID PMC3253549 Editors
Effect of disinfectant, water age, and pipe material on occurrence and persistence of Legionella, mycobacteria, Pseudomonas aeruginosa, and two amoebas	2012	Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Environmental science & technology Periodical, Abbrev. Environ.Sci.Technol. Pub Date Free Form 6-Nov Volume 46 Issue 21 Start Page 11566 Other Pages 11574 Notes LR: 20131121; JID: 0213155; 0 (Chloramines); 0 (Disinfectants); 0 (Drinking Water); 0 (RNA, Bacterial); 0 (RNA, Ribosomal, 16S); 0 (Water Pollutants); 10599-90-3 (chloramine); 4R7X1O2820 (Chlorine); 9002-86-2 (Polyvinyl Chloride); E1UOL152H7 (Iron); 2012/ Place of Publication United States ISSN/ISBN 1520-5851; 0013-936X Accession Number PMID: 23046164 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; IM DOI 10.1021/es303212a [doi] Output Language Unknown(0) PMID 23046164 Abstract Opportunistic pathogens represent a unique challenge because they establish and grow within drinking water systems, yet the factors stimulating their proliferation are largely unknown. The purpose of this study was to examine the influence of pipe materials, disinfectant type, and water age on occurrence and persistence of three opportunistic pathogens (Legionella pneumophila, Mycobacterium avium, and Pseudomonas aeruginosa), broader genera (Legionella and mycobacteria), and two amoeba hosts (Acanthamoeba spp. and Hartmanella vermiformis). Triplicate simulated distribution systems (SDSs) compared iron, cement, and PVC pipe materials fed either chlorinated or chloraminated tap water and were sampled at water ages ranging from 1 day to 5.7 days. Quantitative polymerase chain reaction quantified gene copies of target microorganisms in both biofilm and bulk water. Legionella, mycobacteria, P. aeruginosa, and both amoebas naturally colonized the six SDSs, but L. pneumophila and M. avium were not detected. Disinfectant type and dose was observed to have the strongest influence on the microbiota. Disinfectant decay was noted with water age, particularly in chloraminated SDSs (due to nitrification), generally resulting in increased microbial detection frequencies and densities with water age. The influence of pipe material became apparent at water ages corresponding to low disinfectant residual. Each target microbe appeared to display a distinct response to disinfectant type, pipe materials, water age, and their interactions. Differences between the first and the second samplings (e.g., appearance of Legionella, reduction in P. aeruginosa and Acanthamoeba) suggest a temporally dynamic drinking water microbial community. Descriptors Links Book Title Database Publisher Data Source Authors Wang,H., Masters,S., Hong,Y., Stallings,J., Falkinham,J.O.,3rd, Edwards,M.A., Pruden,A. Original/Translated Title URL Date of Electronic 20121025 PMCID Editors
The cleaning method selected for new PEX pipe installation can affect short-term drinking water quality	2015	Department of Civil Engineering, University of South Alabama, Mobile, AL, USA.; Department of Chemistry, University of South Alabama, Mobile, AL, USA.; Department of Civil Engineering, University of South Alabama, Mobile, AL, USA.; Department of Statistic	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of water and health Periodical, Abbrev. J.Water.Health. Pub Date Free Form Dec Volume 13 Issue 4 Start Page 960 Other Pages 969 Notes JID: 101185420; 0 (Drinking Water); 0 (Water Pollutants, Chemical); 9002-88-4 (Polyethylene); ppublish Place of Publication England ISSN/ISBN 1477-8920; 1477-8920 Accession Number PMID: 26608758 Language eng SubFile Journal Article; IM DOI 10.2166/wh.2015.243 [doi] Output Language Unknown(0) PMID 26608758 Abstract The influence of four different cleaning methods used for newly installed polyethylene (PEX) pipes on chemical and odor quality was determined. Bench-scale testing of two PEX (type b) pipe brands showed that the California Plumbing Code PEX installation method does not maximize total organic carbon (TOC) removal. TOC concentration and threshold odor number values significantly varied between two pipe brands. Different cleaning methods impacted carbon release, odor, as well the level of drinking water odorant ethyl tert-butyl ether. Both pipes caused odor values up to eight times greater than the US federal drinking water odor limit. Unique to this project was that organic chemicals released by PEX pipe were affected by pipe brand, fill/empty cycle frequency, and the pipe cleaning method selected by the installer. Descriptors Links Book Title Database Publisher Data Source Authors Kelley,K.M., Stenson,A.C., Cooley,R., Dey,R., Whelton,A.J. Original/Translated Title URL Date of Electronic PMCID Editors
Release of drinking water contaminants and odor impacts caused by green building cross-linked polyethylene (PEX) plumbing systems	2014	Department of Civil Engineering, University of South Alabama, Mobile, AL, USA.; Department of Chemistry, University of South Alabama, Mobile, AL, USA.; Department of Statistics and Mathematics, University of South Alabama, Mobile, AL, USA.; Lyles School o	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Water research Periodical, Abbrev. Water Res. Pub Date Free Form 15-Dec Volume 67 Issue Start Page 19 Other Pages 32 Notes CI: Copyright (c) 2014; JID: 0105072; 0 (Drinking Water); 0 (Organic Chemicals); 0 (Water Pollutants, Chemical); 7440-44-0 (Carbon); 9002-88-4 (Polyethylene); OTO: NOTNLM; 2014/04/21 [received]; 2014/08/26 [revised]; 2014/08/31 [accepted]; 2014/09/10 [ahe Place of Publication England ISSN/ISBN 1879-2448; 0043-1354 Accession Number PMID: 25259680 Language eng SubFile Evaluation Studies; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; IM DOI 10.1016/j.watres.2014.08.051 [doi] Output Language Unknown(0) PMID 25259680 Abstract Green buildings are increasingly being plumbed with crosslinked polyethylene (PEX) potable water pipe. Tap water quality was investigated at a six month old plumbing system and chemical and odor quality impacts of six PEX pipe brands were examined. Eleven PEX related contaminants were found in the plumbing system; one regulated (toluene) and several unregulated: Antioxidant degradation products, resin solvents, initiator degradation products, or manufacturing aides. Water chemical and odor quality was monitored for new PEX-a, -b and -c pipes with (2 mg/L free chlorine) and without disinfectant over 30 days. Odor and total organic carbon (TOC) levels decreased for all pipes, but odor remained greater than the USA's Environmental Protection Agency's (USEPA) secondary maximum contaminant level. Odors were not attributed to known odorants ethyl-tert-butyl ether (ETBE) or methyl-tert-butyl ether (MTBE). Free chlorine caused odor levels for PEX-a1 pipe to increase from 26 to 75 threshold odor number (TON) on day 3 and affected the rate at which TOC changed for each brand over 30 days. As TOC decreased, the ultraviolet absorbance at 254 nm increased. Pipes consumed as much as 0.5 mg/L as Cl2 during each 3 day stagnation period. Sixteen organic chemicals were identified, including toluene, pyridine, methylene trichloroacetate and 2,4-di-tert-butylphenol. Some were also detected during the plumbing system field investigation. Six brands of PEX pipes sold in the USA and a PEX-a green building plumbing system impacted chemical and drinking water odor quality. Descriptors Links Book Title Database Publisher Elsevier Ltd Data Source Authors Kelley,K.M., Stenson,A.C., Dey,R., Whelton,A.J. Original/Translated Title URL Date of Electronic 20140910 PMCID Editors
An evaluation of the indoor air quality in bars before and after a smoking ban in Austin, Texas	2007	Department of Civil, Architectural, and Environmental Engineering, The University of Texas at Austin, Austin, Texas 78712, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of exposure science & environmental epidemiology Periodical, Abbrev. J.Expo.Sci.Environ.Epidemiol. Pub Date Free Form May Volume 17 Issue 3 Start Page 260 Other Pages 268 Notes LR: 20131121; JID: 101262796; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); 142M471B3J (Carbon Dioxide); 7U1EE4V452 (Carbon Monoxide); 2006/06/28 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1559-0631; 1559-0631 Accession Number PMID: 16804559 Language eng SubFile Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 7500513 [pii] Output Language Unknown(0) PMID 16804559 Abstract This study assessed differences in the indoor air quality and occupancy levels in seventeen bars due to a city-wide smoking ban that took effect on September 1, 2005 in Austin, Texas, USA. We measured the following in each venue before and after the smoking ban: mean number of occupants, mean number of lit cigarettes, temperature, relative humidity, room volume, and PM(2.5), CO, and CO(2) concentrations. Additionally, VOC measurements were conducted at three of the venues. There was not a statistically significant change in occupancy, but the best estimate PM(2.5) concentrations in the venues decreased 71-99%, a significant reduction in all venues, relative to the pre-ban levels; CO concentrations decreased significantly in all but one venue; and concentrations of VOCs known to be emitted from cigarettes decreased to below the detection limit for all but two common compounds. These results suggest that the smoking ban has effectively improved indoor air quality in Austin bars without an associated decrease in occupancy. Descriptors Air Pollutants/analysis, Air Pollution, Indoor/analysis/legislation & jurisprudence/prevention & control, Carbon Dioxide/analysis, Carbon Monoxide/analysis, Environmental Exposure/analysis/prevention & control, Environmental Monitoring, Humans, Particulate Matter/analysis, Program Evaluation, Restaurants/legislation & jurisprudence, Smoking/legislation & jurisprudence/prevention & control, Texas, Tobacco Smoke Pollution/analysis/legislation & jurisprudence/prevention & control Links Book Title Database Publisher Data Source Authors Waring,M. S., Siegel,J. A. Original/Translated Title URL Date of Electronic 20060628 PMCID Editors
Reasons and Motivations for Cigarette Smoking and Barriers against Quitting Among a Sample of Young People in Jeddah, Saudi Arabia	2016	Department of Clinical Biochemistry/Medical Education, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia Email : drmukhtiarbaig@yahoo.com.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Asian Pacific journal of cancer prevention : APJCP Periodical, Abbrev. Asian Pac.J.Cancer.Prev. Pub Date Free Form Volume 17 Issue 7 Start Page 3483 Other Pages 3487 Notes JID: 101130625; ppublish Place of Publication Thailand ISSN/ISBN 1513-7368; 1513-7368 Accession Number PMID: 27509996 Language eng SubFile Journal Article; IM DOI Output Language Unknown(0) PMID 27509996 Abstract BACKGROUND: Cigarette smoking is one of the leading causes of death in the world. Tobacco consumption has grave negative consequences for health so that it is important to understand the reasons and motivations towards cigarette smoking and barriers against quitting smoking among the young generation for developing effective policies to control this widespread problem. MATERIALS AND METHODS: This crosssectional survey was carried out at the Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia. A total of 438 young smokers participated from the University and the general population. Data were collected through anonymous, selfadministered questionnaires in the Arabic language that contained questions about the reasons and motivations towards cigarette smoking and barriers against quitting smoking. The questionnaire also contained several questions regarding knowledge and attitude of the participants towards cigarette smoking. The data was analyzed on SPSS16. RESULTS: The mean age of the respondents was 22.9+/-3.48, out of 438 subjects 87 (19.9%) were married, and 351 (80.1%) were unmarried, and 331 (75.6%) belonged to urban areas while 107 (24.5%) were from the rural areas. Responding to a question about a number of cigarettes smoked per day, 31% answered 1120, 29% answered 2130, and 25% answered 110. Questioned about smokers in the family, 34.5% responded more than one, with 19% for brother and 13% for father. About the reasons for not quitting smoking, 26% described lack of willpower, 25% had no reason, 22% said that people around me smoke, and 15.3% responded stress at home/work. The major motivation for smokers was smoker friends (42%), for 33.8% others, for 12% father/brother and 7.8% media. CONCLUSIONS: There are several avoidable and preventable reasons and barriers against quitting smoking. However, knowledge and attitude about smoking were good, and the majority of the smokers were well aware of the associated hazards. Therefore, there is a need to search out ways and means to help them to quit this addiction. Descriptors Links Book Title Database Publisher Data Source Authors Baig,M., Bakarman,M.A., Gazzaz,Z.J., Khabaz,M.N., Ahmed,T.J., Qureshi,I.A., Hussain,M.B., Alzahrani,A.H., AlShehri,A.A., Basendwah,M.A., Altherwi,F.B., AlShehri,F.M. Original/Translated Title URL Date of Electronic PMCID Editors
Micafungin at physiological serum concentrations shows antifungal activity against Candida albicans and Candida parapsilosis biofilms	2014	Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, Madrid, Spain Instituto de Investigacion Sanitaria Gregorio Maranon, Madrid, Spain mariaguembe@hotmail.com jguineaortega@yahoo.es.; Department of	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Sep Volume 58 Issue 9 Start Page 5581 Other Pages 5584 Notes LR: 20150301; CI: Copyright (c) 2014; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Lipopeptides); R10H71BSWG (micafungin); OID: NLM: PMC4135876; 2014/06/23 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 24957821 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AAC.02738-14 [doi] Output Language Unknown(0) PMID 24957821 Abstract We assessed the in vitro activity of micafungin against preformed Candida biofilms by measuring the concentration of drug causing the most fungal damage and inhibition of regrowth. We studied 37 biofilm-producing Candida spp. strains from blood cultures. We showed that micafungin was active against planktonic and sessile forms of Candida albicans strains and moderately active against Candida parapsilosis sessile cells. Concentrations of micafungin above 2 mug/ml were sufficiently high to inactivate regrowth of Candida sessile cells. Descriptors Links Book Title Database Publisher American Society for Microbiology. All Rights Reserved Data Source Authors Guembe,M., Guinea,J., Marcos-Zambrano,L.J., Fernandez-Cruz,A., Pelaez,T., Munoz,P., Bouza,E. Original/Translated Title URL Date of Electronic 20140623 PMCID PMC4135876 Editors
Shear bond strength of enamel surface treated with air-abrasive system	2002	Department of Clinical Pediatrics, Faculty of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil. borsatto@forp.usp.br	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Brazilian dental journal Periodical, Abbrev. Braz.Dent.J. Pub Date Free Form Volume 13 Issue 3 Start Page 175 Other Pages 178 Notes LR: 20131121; JID: 9214652; 0 (Composite Resins); 0 (Dentin-Bonding Agents); 0 (Phosphoric Acids); 0 (Resin Cements); 0 (Z100 composite resin); 0 (single bond); 454I75YXY0 (Bisphenol A-Glycidyl Methacrylate); 7631-86-9 (Silicon Dioxide); C6V6S92N3C (Zirco Place of Publication Brazil ISSN/ISBN 0103-6440; 0103-6440 Accession Number PMID: 12428591 Language eng SubFile Evaluation Studies; Journal Article; D DOI Output Language Unknown(0) PMID 12428591 Abstract The aim of this study was to evaluate the shear bond strength of a composite resin to dental enamel, using three different surface treatments. Fifteen sound third molars were randomly assigned to three groups. The mesial and distal surfaces were flattened and covered using adhesive tape with a central orifice delimiting the adhesion area (7.07 mm2). Group I, the enamel surface was conditioned with 37% phosphoric acid for 15 s; group II, the surface was treated using air abrasion with aluminum oxide; group III, the enamel surface was treated using an association of air abrasion with aluminum oxide and 37% phosphoric acid. The Single Bond (3M) adhesive system was applied and a Teflon matrix was placed and filled with composite resin Z-100 (3M) and light-cured. The shear bond strength test was performed with a universal testing machine. The acid etching technique and air abrasion with aluminum oxide associated with acid etching had the highest shear bond strength values. Data were subjected to statistical analysis using ANOVA and the Turkey test, and no statistically significant difference in shear bond strength was observed between group I (12.49 +/- 2.85 MPa) and group III (12.59 +/- 2.68 MPa). In contrast, both groups had statistically better shear bond strengths compared to group II (0.29 +/- 0.56 MPa; p < 0.05). Air abrasion with aluminum oxide does not substitute acid etching. The association of these methods to obtain adequate adhesion to the substrate is necessary. Descriptors Acid Etching, Dental, Air Abrasion, Dental, Aluminum Oxide, Analysis of Variance, Bisphenol A-Glycidyl Methacrylate, Composite Resins, Dental Bonding/methods, Dental Enamel/physiology, Dental Stress Analysis, Dentin-Bonding Agents, Humans, Materials Testing, Molar, Phosphoric Acids, Random Allocation, Resin Cements, Shear Strength, Silicon Dioxide, Statistics, Nonparametric, Surface Properties, Zirconium Links Book Title Database Publisher Data Source Authors Borsatto,M. C., Catirse,A. B., Palma Dibb,R. G., Nascimento,T. N., Rocha,R. A., Corona,S. A. Original/Translated Title URL Date of Electronic PMCID Editors
The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress	2012	Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan. khalzoubi@just.edu.jo	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Behavioural brain research Periodical, Abbrev. Behav.Brain Res. Pub Date Free Form 1-Jan Volume 226 Issue 1 Start Page 205 Other Pages 210 Notes LR: 20131121; CI: Copyright (c) 2011; JID: 8004872; 0 (Neuroprotective Agents); 1406-18-4 (Vitamin E); EC 1.11.1.6 (Catalase); EC 1.15.1.1 (Superoxide Dismutase); GAN16C9B8O (Glutathione); 2011/07/09 [received]; 2011/09/06 [revised]; 2011/09/10 [accepted] Place of Publication Netherlands ISSN/ISBN 1872-7549; 0166-4328 Accession Number PMID: 21944940 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.bbr.2011.09.017 [doi] Output Language Unknown(0) PMID 21944940 Abstract Sleep deprivation induces oxidative stress and impairs learning and memory processes. Vitamin E, on the other hand, is a strong antioxidant that has neuroprotective effect on the brain. In this study, we examined the potential protective effect of chronic administration of vitamin E on chronic sleep deprivation-induced cognitive impairment. In addition, possible molecular targets for vitamin E effects on chronic sleep deprivation-induced cognitive impairment were determined. Sleep deprivation was induced in rats using modified multiple platform model. Vitamin E (100mg/kg) was administered to animals by oral gavage. Behavioral study was conducted to test the spatial learning and memory using the radial arm water maze (RAWM). In addition, the hippocampus was dissected out and antioxidant markers including glutathione (GSH), oxidized glutathione (GSSG) and GSH/GSSG, glutathione peroxidase (GPx), catalase, and superoxide dismutase (SOD) were assessed. The results of this project revealed that chronic sleep deprivation impaired both (short- and long-term) memories (P Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Alzoubi,K.H., Khabour,O.F., Rashid,B.A., Damaj,I.M., Salah,H.A. Original/Translated Title URL Date of Electronic 20110916 PMCID Editors

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