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Sustained Waterpipe Tobacco Smoking and Trends Over Time 2015 Center for Research on Media, Technology, and Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of General Internal Medicine, School of Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of Ad
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Preventive Medicine
Periodical, Abbrev.
Am.J.Prev.Med.
Pub Date Free Form
Dec
Volume
49
Issue
6
Start Page
859
Other Pages
867
Notes
LR: 20160311; CI: Copyright (c) 2015; GR: R01 CA140150/CA/NCI NIH HHS/United States; GR: R01 DA001411/DA/NIDA NIH HHS/United States; GR: R01 DA001411/DA/NIDA NIH HHS/United States; GR: R01-CA140150/CA/NCI NIH HHS/United States; JID: 8704773; NIHMS764052;
Place of Publication
Netherlands
ISSN/ISBN
1873-2607; 0749-3797
Accession Number
PMID: 26385163
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.amepre.2015.06.030 [doi]
Output Language
Unknown(0)
PMID
26385163
Abstract
INTRODUCTION: Use of waterpipe tobacco smoking (WTS) is now prevalent among U.S. adolescents. However, the more clinically relevant questions are whether users exhibit sustained patterns of use and whether use is increasing over time relative to other tobacco products. We aimed to examine factors associated with sustained WTS among U.S. adolescents and to compare prevalence trends between WTS and other tobacco products. METHODS: The Monitoring the Future project began assessing WTS among 12th-grade students in 2010. In 2014, we conducted multivariable regression analyses to examine correlates of sustained WTS, which we defined as use at least six times in the past 12 months. We used trend analysis to compare use of WTS and other types of tobacco. RESULTS: Of the 8,737 participants queried from 2010 to 2013, 18.8% (1,639) reported past-year WTS, whereas 7.2% (627) reported sustained use. Sustained WTS was inversely associated with female sex (versus male, OR=0.78, 95% CI=0.63, 0.96); African American race (versus Caucasian, OR=0.26, 95% CI=0.14, 0.48); and increased number of parents in the home (p
Descriptors
Links
Book Title
Database
Publisher
American Journal of Preventive Medicine. Published by Elsevier Inc
Data Source
Authors
Primack,B.A., Freedman-Doan,P., Sidani,J.E., Rosen,D., Shensa,A., James,A.E., Wallace,J.
Original/Translated Title
URL
Date of Electronic
20150915
PMCID
PMC4780332
Editors
Electronic Cigarette Trial and Use among Young Adults: Reasons for Trial and Cessation of Vaping 2015 Center for Survey Research, University of Massachusetts Boston, Boston, MA 02125, USA. lois.biener@umb.edu.; Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. esong@wak
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of environmental research and public health
Periodical, Abbrev.
Int.J.Environ.Res.Public.Health.
Pub Date Free Form
17-Dec
Volume
12
Issue
12
Start Page
16019
Other Pages
16026
Notes
LR: 20160107; GR: R01CA141643-04S2/CA/NCI NIH HHS/United States; JID: 101238455; 6M3C89ZY6R (Nicotine); OID: NLM: PMC4690975; OTO: NOTNLM; 2015/10/02 [received]; 2015/11/30 [revised]; 2015/12/10 [accepted]; epublish
Place of Publication
Switzerland
ISSN/ISBN
1660-4601; 1660-4601
Accession Number
PMID: 26694438
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.3390/ijerph121215039 [doi]
Output Language
Unknown(0)
PMID
26694438
Abstract
This paper identifies predictors of trial and current use, and reasons for trying and ceasing use of electronic cigarettes (e-cigarettes) among young adults, with particular attention to former and never smokers. Data are from a mail survey of a population-based sample of adults aged 18 to 35 (N = 4740) in three U.S. metropolitan areas. Survey items assessed trial and use of e-cigarettes, cigarette smoking status, and reasons for trial and for ceasing use of e-cigarettes. Almost 23% reported trial of e-cigarettes, and 8.4% reported using them in the past month. Current smokers were much more likely to have tried e-cigarettes (70.2%) than both former (32.3%) and never smokers (7.6%; p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Biener,L., Song,E., Sutfin,E.L., Spangler,J., Wolfson,M.
Original/Translated Title
URL
Date of Electronic
20151217
PMCID
PMC4690975
Editors
A longitudinal study of electronic cigarette use among a population-based sample of adult smokers: association with smoking cessation and motivation to quit 2015 Center for Survey Research, University of Massachusetts, Boston, MA lois.biener@umb.edu.; Center for Survey Research, University of Massachusetts, Boston, MA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
17
Issue
2
Start Page
127
Other Pages
133
Notes
LR: 20160202; CI: (c) The Author 2014; GR: #R01CA151384-03/CA/NCI NIH HHS/United States; JID: 9815751; OID: NLM: PMC4375383; 2014/10/09 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25301815
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1093/ntr/ntu200 [doi]
Output Language
Unknown(0)
PMID
25301815
Abstract
AIMS: Increasingly popular electronic cigarettes (e-cigarettes) may be the most promising development yet to end cigarette smoking. However, there is sparse evidence that their use promotes cessation. We investigated whether e-cigarette use increases smoking cessation and/or has a deleterious effect on quitting smoking and motivation to quit. METHODS: Representative samples of adults in 2 US metropolitan areas were surveyed in 2011/2012 about their use of novel tobacco products. In 2014, follow-up interviews were conducted with 695 of the 1,374 baseline cigarette smokers who had agreed to be re-contacted (retention rate: 51%). The follow-up interview assessed their smoking status and history of electronic cigarette usage. Respondents were categorized as intensive users (used e-cigarettes daily for at least 1 month), intermittent users (used regularly, but not daily for more than 1 month), and non-users/triers (used e-cigarettes at most once or twice). RESULTS: At follow-up, 23% were intensive users, 29% intermittent users, 18% had used once or twice, and 30% had not tried e-cigarettes. Logistic regression controlling for demographics and tobacco dependence indicated that intensive users of e-cigarettes were 6 times more likely than non-users/triers to report that they quit smoking (OR: 6.07, 95% CI = 1.11, 33.2). No such relationship was seen for intermittent users. There was a negative association between intermittent e-cigarette use and 1 of 2 indicators of motivation to quit at follow-up. CONCLUSIONS: Daily use of electronic cigarettes for at least 1 month is strongly associated with quitting smoking at follow-up. Further investigation of the underlying reasons for intensive versus intermittent use will help shed light on the mechanisms underlying the associations between e-cigarette use, motivation to quit, and smoking cessation.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Biener,L., Hargraves,J.L.
Original/Translated Title
URL
Date of Electronic
20141009
PMCID
PMC4375383
Editors
Helicobacter pylori infection, not gastroesophageal reflux, is the major cause of inflammation and intestinal metaplasia of gastric cardiac mucosa 2002 Center for Swallowing and Esophageal Disorders and Department of Anatomic Pathology, Cleveland Clinic Foundation, Ohio 44195, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The American Journal of Gastroenterology
Periodical, Abbrev.
Am.J.Gastroenterol.
Pub Date Free Form
Feb
Volume
97
Issue
2
Start Page
302
Other Pages
311
Notes
LR: 20061115; JID: 0421030; ppublish
Place of Publication
United States
ISSN/ISBN
0002-9270; 0002-9270
Accession Number
PMID: 11866266
Language
eng
SubFile
Comparative Study; Journal Article; IM
DOI
10.1111/j.1572-0241.2002.05462.x [doi]
Output Language
Unknown(0)
PMID
11866266
Abstract
OBJECTIVE: The etiology of inflammation below the normal Z-line is an area of intense debate. Some suggest this is the earliest change of chronic gastroesophageal reflux disease (GERD), whereas others indict Helicobacter pylori (H. pylori) as the main cause. The aim of this study was to evaluate the relationship among inflammation of gastric cardiac mucosa (carditis), H. pylori infection, and intestinal metaplasia in patients with GERD and Barrett's esophagus compared with age-matched controls. METHODS: Patients with GERD and Barrett's esophagus were compared with controls undergoing endoscopy for a variety of other conditions. Endoscopic biopsy specimens from the gastric cardia (obtained on retroflexed view), fundus, and antrum were evaluated for inflammation, H. pylori infection, and intestinal metaplasia. RESULTS: The prevalence of H. pylori infection did not significantly differ among the study populations: controls (42%), GERD (33%), and Barrett's esophagus (27%) (p = 0.20). However, the prevalence of carditis significantly decreased from the control group (30%) to those with GERD (23%) and Barrett's esophagus (11%) (p = 0.03). Overall, 42 of 51 (82%) patients with carditis had H. pylori; all had pangastritis. The prevalence of cardia intestinal metaplasia also significantly decreased from the control group (15%) to those with GERD (4%) and Barrett's esophagus (0%) (p = 0.003). Of 13 patients with cardia intestinal metaplasia, 12 had carditis, 10 had H. pylori infection, and seven had intestinal metaplasia elsewhere in the stomach. CONCLUSIONS: Inflammation of gastric cardiac mucosa decreases in prevalence from controls to patients with GERD and Barrett's esophagus and correlates strongly with H. pylori infection. Cardia intestinal metaplasia is associated with H. pylori-related cardiac inflammation and intestinal metaplasia elsewhere in the stomach.
Descriptors
Adult, Age Distribution, Aged, Aged, 80 and over, Analysis of Variance, Barrett Esophagus/complications/pathology, Biopsy, Needle, Cardia/pathology, Case-Control Studies, Cohort Studies, Esophagoscopy/methods, Female, Gastric Mucosa/pathology, Gastritis/epidemiology/etiology/pathology, Gastroesophageal Reflux/complications/pathology, Gastroscopy/methods, Helicobacter Infections/complications/pathology, Helicobacter pylori/isolation & purification, Humans, Intestinal Mucosa/pathology, Male, Middle Aged, Prevalence, Prognosis, Risk Assessment, Risk Factors, Sex Distribution
Links
Book Title
Database
Publisher
Data Source
Authors
Goldblum,J. R., Richter,J. E., Vaezi,M., Falk,G. W., Rice,T. W., Peek,R. M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Reflux disease and Barrett's esophagus 1999 Center for Swallowing and Esophageal Disorders, Dept. of Gastroenterology, The Cleveland Clinic Foundation, Ohio 44195, USA. FalkG@cesmtp.ccf.org
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Endoscopy
Periodical, Abbrev.
Endoscopy
Pub Date Free Form
Jan
Volume
31
Issue
1
Start Page
9
Other Pages
16
Notes
LR: 20051116; JID: 0215166; RF: 45; ppublish
Place of Publication
GERMANY
ISSN/ISBN
0013-726X; 0013-726X
Accession Number
PMID: 10082405
Language
eng
SubFile
Journal Article; Review; IM
DOI
10.1055/s-1999-13643 [doi]
Output Language
Unknown(0)
PMID
10082405
Abstract
Gastroesophageal reflux disease (GERD) is a common clinical problem. New information suggests that infection with Helicobacter pylori may protect patients from developing GERD and its complications. Endoscopy may be used by clinicians to tailor GERD therapy, but an empirical trial of a proton-pump inhibitor may be an alternative diagnostic approach. Studies continue to show that laparoscopic antireflux surgery is a cost-effective treatment option for patients requiring maintenance therapy with proton-pump inhibitors. However, the minimally invasive nature of the operation should not alter the indications for antireflux surgery, especially for patients with atypical symptoms. It remains unclear why some patients with GERD develop Barrett's esophagus, whereas others do not. Recent guidelines suggest that patients with long-standing GERD symptoms, especially white men over 50 years of age, should undergo endoscopy at least once to screen for Barrett's esophagus. Debate concerning short-segment Barrett's esophagus continues. Intestinal metaplasia at a normal-appearing gastroesophageal junction may be associated with intestinal metaplasia of the stomach and infection with H. pylori, whereas short tongues of intestinal metaplasia in the esophagus are associated with GERD. Cancer surveillance is indicated in short-segment Barrett's esophagus, as dysplasia may develop in these patients. Barrett's esophagus is the only known risk factor for the development of esophageal adenocarcinoma, but the incidence of adenocarcinoma may be lower than previously reported. New clinical guidelines for endoscopic surveillance suggest that the surveillance interval should be lengthened to every two years in patients without dysplasia. Newer treatment options, such as thermal ablation and photodynamic therapy, continue to show promise, but are not yet ready for routine clinical use.
Descriptors
Barrett Esophagus/diagnosis/etiology/therapy, Follow-Up Studies, Gastroesophageal Reflux/complications/diagnosis/therapy, Humans
Links
Book Title
Database
Publisher
Data Source
Authors
Falk,G. W.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Group Waterpipe Tobacco Smoking Increases Smoke Toxicant Concentration 2016 Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA;; Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA; Department of Mechanic
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
May
Volume
18
Issue
5
Start Page
770
Other Pages
776
Notes
LR: 20160701; CI: (c) The Author 2015; GR: P50 DA036105/DA/NIDA NIH HHS/United States; GR: P50DA036105/DA/NIDA NIH HHS/United States; GR: R01 CA120142/CA/NCI NIH HHS/United States; GR: R01CA120142/CA/NCI NIH HHS/United States; JID: 9815751; 2015/07/24 [re
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 26659913
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1093/ntr/ntv271 [doi]
Output Language
Unknown(0)
PMID
26659913
Abstract
INTRODUCTION: Waterpipe tobacco smoking is a global health concern. Laboratory research has focused on individual waterpipe users while group use is common. This study examined user toxicant exposure and smoke toxicant yield associated with individual and group waterpipe smoking. METHODS: Twenty-two pairs of waterpipe smokers used a waterpipe individually and as a dyad. Before and after smoking, blood was sampled and expired carbon monoxide (CO) measured; puff topography was recorded throughout. One participant from each pair was selected randomly and their plasma nicotine and expired air CO concentrations were compared when smoking alone to when smoking as part of a dyad. Recorded puff topography was used to machine-produce smoke that was analyzed for toxicant content. RESULTS: There was no difference in mean plasma nicotine concentration when an individual smoked as part of a dyad (mean = 14.9 ng/ml; standard error of the mean [SEM] = 3.0) compared to when smoking alone (mean = 10.0 ng/ml; SEM = 1.5). An individual smoking as part of as a dyad had, on average, lower CO (mean = 15.8 ppm; SEM = 2.0) compared to when smoking alone (mean= 21.3 ppm; SEM = 2.7). When two participants smoked as a dyad they took, on average, more puffs (mean = 109.8; SEM = 7.6) than a singleton smoker (mean = 77.7; SEM = 8.1) and a shorter interpuff interval (IPI; dyad mean = 23.8 seconds; SEM = 1.9; singleton mean = 40.8 seconds; SEM = 4.8). Higher concentrations of several toxicants were observed in dyad-produced smoke. DISCUSSION: Dyad smoking may increase smoke toxicant content, likely due to the dyad's shorter IPIs and greater puff number. More work is needed to understand if group waterpipe smoking alters the health risks of waterpipe tobacco smoking. IMPLICATIONS: This study is the first to measure toxicants in smoke generated from a waterpipe when used by a dyad. Relative to smoke generated by a singleton, dyad smoke had higher concentration of some toxicants. These differences may be attributed to differences in puffing behavior, specifically the shorter IPI and greater puff number observed in the dyad condition. Relative to singleton smokers, dyad smokers were exposed to less CO, but nicotine exposure did not differ. More work is needed to assess the health effects of inhalation of more toxicant-laden smoke during group waterpipe use.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Ramoa,C.P., Shihadeh,A., Salman,R., Eissenberg,T.
Original/Translated Title
URL
Date of Electronic
20151211
PMCID
Editors
Preliminary results of an examination of electronic cigarette user puff topography: the effect of a mouthpiece-based topography measurement device on plasma nicotine and subjective effects 2015 Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA;; Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA;; Center for the Study
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
17
Issue
2
Start Page
142
Other Pages
149
Notes
LR: 20160519; CI: (c) The Author 2014; GR: P50 DA036105/DA/NIDA NIH HHS/United States; GR: P50DA036105/DA/NIDA NIH HHS/United States; JID: 9815751; 6M3C89ZY6R (Nicotine); OID: NLM: PMC4838000; 2014/09/19 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 25239957
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1093/ntr/ntu186 [doi]
Output Language
Unknown(0)
PMID
25239957
Abstract
INTRODUCTION: Electronic cigarettes (ECIGs) heat a nicotine-containing solution; the resulting aerosol is inhaled by the user. Nicotine delivery may be affected by users' puffing behavior (puff topography), and little is known about the puff topography of ECIG users. Puff topography can be measured using mouthpiece-based computerized systems. However, the extent to which a mouthpiece influences nicotine delivery and subjective effects in ECIG users is unknown. METHODS: Plasma nicotine concentration, heart rate, and subjective effects were measured in 13 experienced ECIG users who used their preferred ECIG and liquid (>/= 12 mg/ml nicotine) during 2 sessions (with or without a mouthpiece). In both sessions, participants completed an ECIG use session in which they were instructed to take 10 puffs with 30-second inter-puff intervals. Puff topography was recorded in the mouthpiece condition. RESULTS: Almost all measures of the effects of ECIG use were independent of topography measurement. Collapsed across session, mean plasma nicotine concentration increased by 16.8 ng/ml, and mean heart rate increased by 8.5 bpm (ps
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Spindle,T.R., Breland,A.B., Karaoghlanian,N.V., Shihadeh,A.L., Eissenberg,T.
Original/Translated Title
URL
Date of Electronic
20140919
PMCID
PMC4838000
Editors
Association between tobacco and alcohol use among young adult bar patrons: a cross-sectional study in three cities 2014 Center for Tobacco Control Research and Education and Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, 530 Parnassus Avenue, Suite 366, San Francisco, CA 94143, USA. pling@medicine.ucsf.edu.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
24-May
Volume
14
Issue
Start Page
500
Other Pages
2458-14-500
Notes
LR: 20151123; GR: CA-113710/CA/NCI NIH HHS/United States; GR: R01 CA-87472/CA/NCI NIH HHS/United States; GR: U01 CA-154240/CA/NCI NIH HHS/United States; JID: 100968562; OID: NLM: PMC4055258; 2013/09/27 [received]; 2014/05/13 [accepted]; 2014/05/24 [aheado
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 24886521
Language
eng
SubFile
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2458-14-500 [doi]
Output Language
Unknown(0)
PMID
24886521
Abstract
BACKGROUND: Bars and nightclubs are key public venues where young adults congregate and use both tobacco and alcohol, and young adult bar patrons are at high risk for substance use. This study examined the association between cigarette smoking and alcohol use among a random sample of young adult bar patrons from three different cities in the USA. METHODS: Cross-sectional data was collected from a random sample of young adult bar patrons aged 18-29 in San Diego, CA (N = 1,150), Portland, ME (N = 1,019), and Tulsa, OK (N = 1,106) from 2007-2010 (response rate 88%) using randomized time location sampling. Respondents reported the number of days they smoked cigarettes, drank alcohol, and binge drank in the past 30 days. Multinomial logistic regression was used to analyze the association between smoking (nonsmoker, occasional smoker, and regular smoker) and drinking and binge drinking for each city controlling for age, gender, race/ethnicity, and education. Predicted probabilities of each smoking category were calculated by drinking and binge drinking status. The association between smoking and drinking and binge drinking among combined samples was also analyzed, controlling for demographic variables and city. RESULTS: Respondents reported high current smoking rates, ranging from 51% in Portland to 58% in Tulsa. Respondents in Tulsa were more likely to report regular smoking than those in San Diego and Portland, with demographic variables being controlled. Young adult bar patrons also exhibited a strong association between smoking and drinking. In general, as the frequency of drinking and binge drinking increased, the predicted probability of being a smoker, especially a regular smoker, increased in each city. CONCLUSIONS: Young adult bar patrons consistently reported a high smoking rate and a strong relationship between smoking and drinking, regardless of the different bar cultures and tobacco control contexts in each of the three cities. While smoke-free bar policies were negatively associated with regular smoking, these policies alone may not be enough to influence the association between smoking and drinking, particularly if tobacco marketing continues in these venues, or in the absence of programs specifically addressing the co-use of tobacco and alcohol.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Jiang,N., Lee,Y.O., Ling,P.M.
Original/Translated Title
URL
Date of Electronic
20140524
PMCID
PMC4055258
Editors
Concentrations of the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in sidestream cigarette smoke increase after release into indoor air: results from unpublished tobacco industry research 2007 Center for Tobacco Control Research and Education and the Lung Biology Center, Department of Medicine, University of California San Francisco, Box 0854, San Francisco, CA 94143-1390, USA. sschick@medsfgh.ucsf.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Periodical, Abbrev.
Cancer Epidemiol.Biomarkers Prev.
Pub Date Free Form
Aug
Volume
16
Issue
8
Start Page
1547
Other Pages
1553
Notes
LR: 20151119; GR: CA-87472/CA/NCI NIH HHS/United States; JID: 9200608; 0 (Air Pollutants); 0 (Carcinogens); 0 (Nitrosamines); 0 (Tobacco Smoke Pollution); 31C4KY9ESH (Nitric Oxide); 64091-91-4 (4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone); 6M3C89Z
Place of Publication
United States
ISSN/ISBN
1055-9965; 1055-9965
Accession Number
PMID: 17684127
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
16/8/1547 [pii]
Output Language
Unknown(0)
PMID
17684127
Abstract
Research has shown that the toxicity of sidestream cigarette smoke, the primary constituent of secondhand smoke, increases over time. To find potential mechanisms that would explain the increase in sidestream smoke toxicity over time, we analyzed unpublished research reports from Philip Morris Co. using the internal tobacco industry documents now available at the University of California San Francisco Legacy Tobacco Documents Library and other Web sites. Unpublished research from Philip Morris Tobacco Company shows that 4-(methylnitrosamino)-I-(3-pyridyl)-1-butanone (NNK), a highly carcinogenic tobacco-specific nitrosamine, can form in sidestream cigarette smoke after it has been released into ambient air. In experiments done between 1983 and 1997, Philip Morris scientists measured the concentration of NNK in sidestream smoke in a sealed stainless steel test chamber at initial particle concentrations of 24 mg/m(3) over the course of 6 to 18 h. They repeatedly showed that airborne NNK concentrations in sidestream cigarette smoke can increase by 50% to 200% per hour during the first 6 h after cigarettes are extinguished. Two experiments done in a real office showed that NNK concentrations increase for the first 2 h after cigarettes are extinguished. If NNK formation also occurs in the lower smoke concentrations observed in real smoking environments, these results suggest that nitrosation of nicotine and/or nicotine breakdown products in aging secondhand smoke is a significant contributor to nitrosamine exposure in humans.
Descriptors
Air Pollutants/analysis, Air Pollution, Indoor/analysis, Carcinogens/analysis/chemistry, Humans, Humidity, Nicotine/chemistry, Nitric Oxide/analysis/chemistry, Nitrogen Dioxide/analysis/chemistry, Nitrosamines/analysis/chemistry, Nitrosation, Temperature, Time Factors, Tobacco Industry, Tobacco Smoke Pollution/analysis
Links
Book Title
Database
Publisher
Data Source
Authors
Schick,S. F., Glantz,S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Electronic cigarette use among Korean adolescents: a cross-sectional study of market penetration, dual use, and relationship to quit attempts and former smoking 2014 Center for Tobacco Control Research and Education, University of California San Francisco, San Francisco, California.; Center for Tobacco Control Research and Education, University of California San Francisco, San Francisco, California.; Center for Tobacc
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Periodical, Abbrev.
J.Adolesc.Health
Pub Date Free Form
Jun
Volume
54
Issue
6
Start Page
684
Other Pages
690
Notes
LR: 20151119; CI: Copyright (c) 2014; GR: CA-113710/CA/NCI NIH HHS/United States; GR: R25 CA113710/CA/NCI NIH HHS/United States; JID: 9102136; NIHMS540345; OID: NLM: NIHMS540345; OID: NLM: PMC4031306; OTO: NOTNLM; 2013/07/24 [received]; 2013/10/23 [revise
Place of Publication
United States
ISSN/ISBN
1879-1972; 1054-139X
Accession Number
PMID: 24274973
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.jadohealth.2013.11.003 [doi]
Output Language
Unknown(0)
PMID
24274973
Abstract
PURPOSE: As elsewhere, in South Korea electronic cigarettes (e-cigarettes) are marketed, in part, as a smoking cessation aid. We assessed the prevalence of e-cigarette use among Korean adolescents and the relationship between e-cigarette use and current (past 30-day) smoking, cigarettes/day, attempts to quit conventional cigarettes, and ceasing to use cigarettes. METHODS: Data from the 2011 Korean Youth Risk Behavior Web-based Survey of 75,643 students aged 13-18 years were analyzed with logistic regression. RESULTS: A total of 9.4% (8.0% ever-dual users who were concurrently using e-cigarettes and smoking conventional cigarettes and 1.4% ever-e-cigarette only users) of Korean adolescents have ever used e-cigarettes and 4.7% were current (past 30-day) e-cigarette users (3.6% dual users and 1.1% e-cigarettes only). After adjusting for demographics, current cigarette smokers were much more likely to use e-cigarettes than were nonsmokers. Among current cigarette smokers, those who smoked more frequently were more likely to be current e-cigarette users. The odds of being an e-cigarette user were 1.58 times (95% confidence interval, 1.39-1.79) higher among students who had made an attempt to quit than for those who had not. It was rare for students no longer using cigarettes to be among current e-cigarette users (odds ratio, .10; confidence interval, .09-.12). CONCLUSIONS: Some Korean adolescents may be responding to advertising claims that e-cigarettes are a cessation aid: those who had made an attempt to quit were more likely to use e-cigarettes but less likely to no longer use cigarettes. E-cigarette use was strongly associated with current and heavier cigarette smoking.
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Book Title
Database
Publisher
Society for Adolescent Health and Medicine. Published by Elsevier Inc
Data Source
Authors
Lee,S., Grana,R.A., Glantz,S.A.
Original/Translated Title
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Date of Electronic
20131122
PMCID
PMC4031306
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