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Cytotoxic effects of BADGE (bisphenol A diglycidyl ether) and BFDGE (bisphenol F diglycidyl ether) on Caco-2 cells in vitro 2006 Microbiology and Biotoxins Area, ANFACO-CECOPESCA, Campus Univ de Vigo, Vigo, Pontevedra, Spain.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Archives of Toxicology
Periodical, Abbrev.
Arch.Toxicol.
Pub Date Free Form
Nov
Volume
80
Issue
11
Start Page
748
Other Pages
755
Notes
LR: 20131121; JID: 0417615; 0 (Actins); 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (bisphenol F diglycidyl ether); 36015-30-2 (Propidium); EC 1.1.1.27 (L-Lactate Dehydrogenase); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); 2006/03/21 [received]
Place of Publication
Germany
ISSN/ISBN
0340-5761; 0340-5761
Accession Number
PMID: 16783546
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s00204-006-0121-1 [doi]
Output Language
Unknown(0)
PMID
16783546
Abstract
Bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) are used as starting substances for the manufacturing of epoxy resins used in internal can coatings. They are obtained by a condensation reaction between epichlorohydrin with bisphenol A and bisphenol F, respectively. These potential endocrine disrupting chemicals are able to enter the food chain and to reach the intestinal epithelium, causing structural and functional damages. The human colorectal adenocarcinoma cell line Caco-2 is a widely used in vitro model of the intestinal cells. The aim of this study was to characterize BADGE and BFDGE toxicity in Caco-2 cells, in particular, at the cellular and molecular level. Using several approaches, we characterized BADGE- and BFDGE-induced cell toxicity in Caco-2 cells. The treatment was done using different concentrations up to cytotoxic doses and different times of exposure to the agents. We evaluated the effect of these compounds on cell morphology, cell detachment, cell proliferation, F-actin disruption and plasma membrane integrity. Both compounds are able to induce morphological changes, cell detachment from the substratum and to inhibit cell proliferation, being these effects time and dose-dependent. Moreover, BADGE and BFDGE induce F-actin depolymerization, this effect is very potent at 24 h of incubation with the agents and a complete F-actin disruption can be observed at 200 microM BADGE or BFDGE. In addition, cell integrity is not damaged, since neither propidium iodide uptake nor LDH release takes place in Caco-2 cells exposed to high doses of these agents for 24 h.
Descriptors
Actins/metabolism, Benzhydryl Compounds, Caco-2 Cells, Cell Adhesion/drug effects, Cell Membrane/drug effects/metabolism, Cell Proliferation/drug effects, Cytoskeleton/drug effects, Epoxy Compounds/toxicity, Humans, L-Lactate Dehydrogenase/metabolism, Propidium/metabolism
Links
Book Title
Database
Publisher
Data Source
Authors
Ramilo,G., Valverde,I., Lago,J., Vieites,J. M., Cabado,A. G.
Original/Translated Title
URL
Date of Electronic
20060617
PMCID
Editors
Bacterial species associated with traditional starter cultures used for fermented bamboo shoot production in Manipur state of India 2010 Microbial Resources Division, Institute of Bioresources and Sustainable Development, Takyelpat Institutional Area, Imphal-795001, Manipur, India. saccharomyces@rediffmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of food microbiology
Periodical, Abbrev.
Int.J.Food Microbiol.
Pub Date Free Form
30-Sep
Volume
143
Issue
2-Jan
Start Page
1
Other Pages
8
Notes
CI: Copyright 2010; JID: 8412849; 0 (DNA, Bacterial); 0 (DNA, Intergenic); 0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S); 0 (RNA, Ribosomal, 23S); 2010/01/23 [received]; 2010/06/16 [revised]; 2010/07/10 [accepted]; 2010/07/15 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1879-3460; 0168-1605
Accession Number
PMID: 20696489
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.ijfoodmicro.2010.07.008 [doi]
Output Language
Unknown(0)
PMID
20696489
Abstract
Soidon is a non-salted acidic fermented food prepared from the succulent bamboo shoot tip of Schizostachyum capitatum Munro by using a traditional liquid starter called "soidon mahi" in Manipur state of India. In this study, 163 bacterial isolates associated with this starter samples were identified and their population distribution was investigated by amplified ribosomal DNA restriction analysis (ARDRA), 16S rDNA sequencing and randomly amplified polymorphic DNA (RAPD) analysis. This acidic starter (pH 4.5+/-0.15) was dominated by a characteristic association of Bacillus and lactic acid bacteria (LAB) together. The population distribution of dominant species were Bacillus subtilis 29.3%, Bacillus cereus 35.7%, Bacillus pumilus 2.6%, Lactobacillus brevis 9.6%, Lactobacillus plantarum 5.1%, Carnobacterium sp. 11.9%, Enterococcus faecium 1.2% and Pseudomonas fluorescens 4.6%. Alarming population load (10(6)-10(7)cfu/ml) of B. cereus in 87% of starter samples studied should raise concern regarding biosafety of soidon consumption. PCR amplification of 16S-23S rDNA intergenic transcribed spacer (ITS) region and ITS-RFLP profiles revealed a high diversity with eight subgroups in B. subtilis, five subgroups in B. cereus and three subgroups in L. brevis isolates. The most abundant B. subtilis subgroup IB.1 distributed in most of the samples showed very less clonal variability during RAPD analysis. The molecular methods used in this study identified the dominant strains of Bacillus and LAB distributed in most of the starter samples. These dominant strains of B. subtilis, L. brevis and L. plantarum would allow for developing a defined starter culture for the production of quality soidon.
Descriptors
Bacteria/classification/genetics/growth & development, Bacterial Load, Bacterial Typing Techniques/methods, Bambusa/metabolism/microbiology, DNA, Bacterial/analysis, DNA, Intergenic, DNA, Ribosomal, Fermentation, Food Handling, Food Microbiology, Food Safety, India, Plant Shoots, RNA, Ribosomal, 16S, RNA, Ribosomal, 23S, Random Amplified Polymorphic DNA Technique, Sequence Analysis, DNA
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Jeyaram,K., Romi,W., Singh,T. A., Devi,A. R., Devi,S. S.
Original/Translated Title
URL
Date of Electronic
20100715
PMCID
Editors
Three-phase succession of autochthonous lactic acid bacteria to reach a stable ecosystem within 7 days of natural bamboo shoot fermentation as revealed by different molecular approaches 2015 Microbial Resources Division, Institute of Bioresources and Sustainable Development (IBSD), Takyelpat Institutional Area, Imphal, 795001, Manipur, India.; Department of Biotechnology, Gauhati University, Guwahati, 781014, Assam, India.; Department of Biot
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Molecular ecology
Periodical, Abbrev.
Mol.Ecol.
Pub Date Free Form
Jul
Volume
24
Issue
13
Start Page
3372
Other Pages
3389
Notes
CI: (c) 2015; GENBANK/KJ095611; GENBANK/KJ095612; GENBANK/KJ095613; GENBANK/KJ095614; GENBANK/KJ095615; GENBANK/KJ095616; GENBANK/KJ095617; GENBANK/KJ095618; GENBANK/KJ095619; GENBANK/KJ095620; GENBANK/KJ095621; GENBANK/KJ095627; GENBANK/KJ095628; GENBANK
Place of Publication
England
ISSN/ISBN
1365-294X; 0962-1083
Accession Number
PMID: 25963776
Language
eng
SubFile
Journal Article; IM
DOI
10.1111/mec.13237 [doi]
Output Language
Unknown(0)
PMID
25963776
Abstract
Microbial community structure and population dynamics during spontaneous bamboo shoot fermentation for production of 'soidon' (indigenous fermented food) in North-east India were studied using cultivation-dependent and cultivation-independent molecular approaches. Cultivation-dependent analyses (PCR-amplified ribosomal DNA restriction analysis and rRNA gene sequencing) and cultivation-independent analyses (PCR-DGGE, qPCR and Illumina amplicon sequencing) were conducted on the time series samples collected from three independent indigenous soidon fermentation batches. The current findings revealed three-phase succession of autochthonous lactic acid bacteria to attain a stable ecosystem within 7 days natural fermentation of bamboo shoots. Weissella spp. (Weissella cibaria, uncultured Weissella ghanensis) and Lactococcus lactis subsp. cremoris predominated the early phase (1-2 days) which was joined by Leuconostoc citreum during the mid-phase (3 days), while Lactobacillus brevis and Lactobacillus plantarum emerged and became dominant in the late phase (5-7 days) with concurrent disappearance of W. cibaria and L. lactis subsp. cremoris. Lactococcus lactis subsp. lactis and uncultured Lactobacillus acetotolerans were predominantly present throughout the fermentation with no visible dynamics. The above identified dominant bacterial species along with their dynamics can be effectively utilized for designing a starter culture for industrialization of soidon production. Our results showed that a more realistic view on the microbial ecology of soidon fermentation could be obtained by cultivation-dependent studies complemented with cultivation-independent molecular approaches. Moreover, the critical issues to be considered for reducing methodological biases while studying the microbial ecology of traditional food fermentation were also highlighted with this soidon fermentation model.
Descriptors
Links
Book Title
Database
Publisher
John Wiley & Sons Ltd
Data Source
Authors
Romi,W., Ahmed,G., Jeyaram,K.
Original/Translated Title
URL
Date of Electronic
20150615
PMCID
Editors
Distribution and molecular characterization of genes encoding CTX-M and AmpC beta-lactamases in Escherichia coli isolated from an Indian urban aquatic environment 2015 Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110021, India.; Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Science of the total environment
Periodical, Abbrev.
Sci.Total Environ.
Pub Date Free Form
1-Feb
Volume
505
Issue
Start Page
350
Other Pages
356
Notes
CI: Copyright (c) 2014; JID: 0330500; 0 (Bacterial Proteins); EC 3.5.2.- (beta-lactamase CTX-M-15); EC 3.5.2.6 (AmpC beta-lactamases); EC 3.5.2.6 (beta-Lactamases); OTO: NOTNLM; 2014/06/16 [received]; 2014/08/14 [revised]; 2014/09/25 [accepted]; 2014/10/2
Place of Publication
Netherlands
ISSN/ISBN
1879-1026; 0048-9697
Accession Number
PMID: 25461036
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.scitotenv.2014.09.084 [doi]
Output Language
Unknown(0)
PMID
25461036
Abstract
Aquatic environments harboring antibiotic resistant Escherichia coli constitute an important public health concern. Thus, it is important to characterize the resistance genetic elements of waterborne E. coli. It is also important to identify the predominant clonal groups/phylogroups represented by resistant strains to understand the epidemiology of antibiotic resistant E. coli in natural environments, and to identify the role of well-established genotypes in the spread of resistance in a particular geographical area through natural environments. In the present investigation, E. coli strains (n=126) isolated from various points along the river Yamuna traversing through the National Capital Territory of Delhi (India) were grouped phylogenetically. A collection of 61 strains representing all phylogroups was investigated for extended-spectrum beta-lactamase (ESBL) and AmpC production. blaTEM, blaSHV and blaCTX-M genes were detected and analyzed, promoter/attenuator mutations associated with chromosomally-mediated AmpC overexpression were identified, and plasmid-mediated ampC was determined. blaTEM was the most widespread (100%) gene followed by bla(CTX-M) (16%), and plasmid-mediated ampC (3%). bla(CTX-M-15) and bla(CMY-42) were identified as the genes encoding CTX-M type ESBL and CIT type AmpC beta-lactamases, respectively. CTX-M-15 ESBL phenotype was most common in phylogroup D (50%), followed by phylogroups B1 (30%), and A (20%). E. coli that produce plasmid-mediated AmpC were rare and present only in phylogroup D. Presence of multi beta-lactam resistance, bla(CTX-M-15) and bla(CMY-42) in waterborne E. coli belonging to virulence-associated phylogroup D highlights the need for routine surveillance of resistance determinants in aquatic environments. This is also the first report for the presence of bla(CMY-42) in waterborne E. coli.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Bajaj,P., Singh,N.S., Kanaujia,P.K., Virdi,J.S.
Original/Translated Title
URL
Date of Electronic
20141029
PMCID
Editors
To Regulate or Not to Regulate? Views on Electronic Cigarette Regulations and Beliefs about the Reasons for and against Regulation 2016 Michigan State University, Department of Advertising and Public Relations, College of Communication Arts and Science, 404 Wilson Road, Lansing, Michigan, United States of America.; Harvard University, TH Chan School of Public Health, Department of Social
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
12-Aug
Volume
11
Issue
8
Start Page
e0161124
Other Pages
Notes
JID: 101285081; 2016 [ecollection]; 2016/03/22 [received]; 2016/07/30 [accepted]; 2016/08/12 [epublish]; epublish
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 27517716
Language
eng
SubFile
Journal Article; IM
DOI
10.1371/journal.pone.0161124 [doi]
Output Language
Unknown(0)
PMID
27517716
Abstract
BACKGROUND: Policies designed to restrict marketing, access to, and public use of electronic cigarettes (e-cigarettes) are increasingly under debate in various jurisdictions in the US. Little is known about public perceptions of these policies and factors that predict their support or opposition. METHODS: Using a sample of US adults from Amazon Mechanical Turk in May 2015, this paper identifies beliefs about the benefits and costs of regulating e-cigarettes and identifies which of these beliefs predict support for e-cigarette restricting policies. RESULTS: A higher proportion of respondents agreed with 8 different reasons to regulate e-cigarettes (48.5% to 83.3% agreement) versus 7 reasons not to regulate e-cigarettes (11.5% to 18.9%). The majority of participants agreed with 7 out of 8 reasons for regulation. When all reasons to regulate or not were included in a final multivariable model, beliefs about protecting people from secondhand vapor and protecting youth from trying e-cigarettes significantly predicted stronger support for e-cigarette restricting policies, whereas concern about government intrusion into individual choices was associated with reduced support. DISCUSSION: This research identifies key beliefs that may underlie public support or opposition to policies designed to regulate the marketing and use of e-cigarettes. Advocates on both sides of the issue may find this research valuable in developing strategic campaigns related to the issue. IMPLICATIONS: Specific beliefs of potential benefits and costs of e-cigarette regulation (protecting youth, preventing exposure to secondhand vapor, and government intrusion into individual choices) may be effectively deployed by policy makers or health advocates in communicating with the public.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Sanders-Jackson,A., Tan,A.S., Bigman,C.A., Mello,S., Niederdeppe,J.
Original/Translated Title
URL
Date of Electronic
20160812
PMCID
Editors
Meta-analyses of the effect of symptoms of gastroesophageal reflux on the risk of Barrett's esophagus 2010 Michigan Institute for Clinical and Health Research, Ann Arbor, Michigan, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The American Journal of Gastroenterology
Periodical, Abbrev.
Am.J.Gastroenterol.
Pub Date Free Form
Aug
Volume
105
Issue
8
Start Page
1729, 1730
Other Pages
7; quiz 1738
Notes
LR: 20141203; GR: K23 DK079291/DK/NIDDK NIH HHS/United States; GR: K23 DK079291/DK/NIDDK NIH HHS/United States; GR: K23 DK079291-04/DK/NIDDK NIH HHS/United States; JID: 0421030; RF: 52; NIHMS217992; OID: NLM: NIHMS217992; OID: NLM: PMC2916949; 2010/05/18
Place of Publication
United States
ISSN/ISBN
1572-0241; 0002-9270
Accession Number
PMID: 20485283
Language
eng
SubFile
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review; IM
DOI
10.1038/ajg.2010.194 [doi]
Output Language
Unknown(0)
PMID
20485283
Abstract
OBJECTIVES: Esophageal adenocarcinoma (EAC) is a devastating disease that has risen in incidence over the past several decades. Barrett's esophagus (BE) is an associated premalignant lesion. Current preventative efforts rely on endoscopic screening of individuals with gastroesophageal reflux disease (GERD) symptoms and surveillance endoscopy for those with BE. However, some recent studies have found a high prevalence of BE in patients without GERD, and others have found little or no association with GERD. We hypothesized that studies of higher-quality design show weaker associations of GERD with BE, and that GERD is only weakly associated with short-segment Barrett's esophagus (SSBE). METHODS: We performed a systematic literature search in multiple online electronic databases regardless of language. Eligible studies required visualization of columnar mucosa and histological confirmation of intestinal metaplasia, and GERD symptoms ascertained by questionnaire or interview. The highest-quality sampling design was defined a priori by both cases and controls identified among unselected research volunteers ("research design") rather than by patients selected for endoscopy for clinical indications ("clinical design"), which introduces selection and ascertainment bias. A priori, heterogeneity was defined by Cochrane's Q P<0.20 and the inconsistency index (I(2); 25% low, 50% moderate, and 75% high). Heterogeneity of results can reflect significant differences in study design or effect modification by strata of outcomes. RESULTS: Systematic review identified 13,392 citations. Evaluation identified 108 potentially relevant journal articles, of which 26 met eligibility. Of these, 14 studies identified cases of BE and controls based on clinical indication ("clinical design"), and 6 used the "research design." The remaining six studies identified cases of BE from patients undergoing endoscopy for clinical indication and controls among patients without known BE ("cases clinical/controls research"). The summary odds ratio (OR) for the association of GERD with BE from all studies was 2.90 (95% confidence interval (CI), 1.86-4.54), but the results were very heterogeneous (P=0.0001; I(2)=89%). When stratified by BE length and sampling design, the studies with clinical design showed substantial, but heterogeneous, associations with SSBE (OR, 2.38; 95% CI, 1.21-4.70; P=0.02; I(2)=62%), and stronger and homogeneous association with long-segment BE (LSBE; fixed effects OR, 2.96; 95% CI, 1.69-5.19; P=0.25; I(2)=25%). In the research study design, stratifying by length of BE resolved the heterogeneity and showed a strong association between GERD and LSBE (fixed effects OR, 4.92; 95% CI, 2.01-12.0; P=0.30; I(2)=19%) and no association with SSBE (fixed effects OR, 1.15; 95% CI, 0.763-1.73; P=0.84; I(2)=0%). Funnel plots showed potential evidence for bias against dissemination of small negative studies. CONCLUSIONS: In the highest-quality studies, GERD symptoms are not associated with SSBE, but increased the odds of LSBE by fivefold. GERD symptoms can serve as a reliable predictor of LSBE, but not SSBE. If SSBE is considered worthy of identification, then current screening practices do not select patients at risk for endoscopy, and alternative methods of selection for screening need to be developed.
Descriptors
Barrett Esophagus/etiology/pathology/prevention & control, Esophagoscopy, Gastroesophageal Reflux/complications/pathology, Humans, Precancerous Conditions/etiology/pathology/prevention & control, Risk
Links
Book Title
Database
Publisher
Data Source
Authors
Taylor,J. B., Rubenstein,J. H.
Original/Translated Title
URL
Date of Electronic
20100518
PMCID
PMC2916949
Editors
A global approach to childhood lead poisoning prevention 2003 Meyer, P.A., CDC/NCEH/EEHS/LPPB, MS F-30, Atlanta, GA 30333, United States
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of hygiene and environmental health
Periodical, Abbrev.
Int.J.Hyg.Environ.Health
Pub Date Free Form
/
Volume
206
Issue
5-Apr
Start Page
363
Other Pages
369
Notes
Place of Publication
ISSN/ISBN
1438-4639
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Childhood lead poisoning is an important, preventable environmental disease affecting millions of children around the world. The effects of lead are well known and range from delayed and adversely affected neurodevelopment to severe health outcomes including seizures, coma, and death. This article reviews the childhood effects of lead poisoning, the approach being taken to the problem in the United States, and the obstacles faced by developing nations in dealing with lead exposure. The United States has attacked the childhood lead poisoning problem by attempting to eliminate sources of exposure, including gasoline, solder in water pipes and cans, and industrial emissions. These actions have resulted in a dramatic reduction in the number of children with elevated blood lead levels in the United States over the last two decades. However, many developing countries are just beginning to address the problem. Successful efforts will need to incorporate epidemiologic methods, source identification, enforced regulations, and a long-term government commitment to eliminating lead as a threat to the next generation of children.
Descriptors
gasoline, lead, battery industry, ceramics, child, child death, cognitive defect, coma, cooperation, developing country, developmental disorder, disease course, environmental disease, environmental exposure, government, health care system, health hazard, health program, health promotion, human, law enforcement, lead blood level, lead poisoning, nervous system development, neurologic disease, organization, pipeline, policy, pollution control, review, risk assessment, seizure, procedures, United States
Links
Book Title
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
Meyer,P. A., McGeehin,M. A., Falk,H.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Determinants of lead concentration in the umbilical cord blood of 9189 newborns of a birth cohort in the government district of Braunschweig 1992 Meyer, J., Kreiskrankenhaus Wittmund.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Zentralblatt für Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine
Periodical, Abbrev.
Zentralbl.Hyg.Umweltmed.
Pub Date Free Form
/
Volume
192
Issue
6
Start Page
522
Other Pages
533
Notes
Place of Publication
ISSN/ISBN
0934-8859
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
From September 1985 until August 1986 the possibility of lead concentration determination in umbilical cord blood was offered to all neonates in the district of Braunschweig by the Ministry of Social Affairs of Lower Saxony. A geometric mean concentration of 3.76 +/- 1.69 micrograms Pb/dl was found in 9189 neonates, being 64% of the total birth cohort. The median concentration was 3.59 micrograms/dl. 4.7% of the children showed concentrations of above 10 micrograms/dl. Lead concentrations of twins showed a strong linear correlation (r = + 0.94). They were higher than those of singleton births (p = 0.02). Lead concentrations in neonates were significantly associated with the age of the mother and with the birthweight of the newborn. Seasonal differentials were significant with higher values in summer (4.39 +/- 1.8 micrograms Pb/dl) compared to winter (3.25 +/- 1.5 micrograms/dl). Duration of daily participation in road traffic was independent of blood lead concentrations. Potential occupational lead exposure of a member of the household was also no significant risk factor for higher lead concentration in the newborn. Family homes constructed before 1955 and those with lead water pipes were associated with significant increases of lead concentrations in neonates. Neighborhood was also significantly associated, with higher values in those living by main roads. In the southern part of the district lead concentrations were about 10% higher than in the northern part. Concentrations in neonates coming from cities were the same as in those coming from rural areas. Newborns from old lead mining and processing areas in the Harz mountains, in particular those coming from Oker-Harlingerode, had low lead concentrations in umbilical cord blood.
Descriptors
lead, article, blood, chemistry, cohort analysis, environmental exposure, exhaust gas, female, fetomaternal transfusion, fetus blood, Germany, housing, human, maternal age, mining, newborn, occupational exposure, pregnancy, risk factor, rural population, season, twins, urban population
Links
Book Title
Determinanten der Bleikonzentration im Nabelschnurblut von 9189 Neugeborenen eines Geburtsjahrgangs im Regierungsbezirk Braunschweig.
Database
MEDLINE
Publisher
Data Source
Embase
Authors
Meyer,J., Geuenich,H. H., Robra,B. P., Windorfer,A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Prevalence and characteristics of dyspepsia among college students in Zhejiang Province 2014 Meng Li, Bin Lu, Li Chu, Hong Zhou, Ming-Yan Chen, Department of Gastroenterology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China.; Meng Li, Bin Lu, Li Chu, Hong Zhou, Ming-Yan Chen, Department
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
World journal of gastroenterology
Periodical, Abbrev.
World J.Gastroenterol.
Pub Date Free Form
7-Apr
Volume
20
Issue
13
Start Page
3649
Other Pages
3654
Notes
LR: 20151119; JID: 100883448; OID: NLM: PMC3974534; OTO: NOTNLM; 2013/07/17 [received]; 2013/11/19 [revised]; 2014/01/02 [accepted]; ppublish
Place of Publication
China
ISSN/ISBN
2219-2840; 1007-9327
Accession Number
PMID: 24707150
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.3748/wjg.v20.i13.3649 [doi]
Output Language
Unknown(0)
PMID
24707150
Abstract
AIM: To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS: Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and March 2011 to participate in the self-report survey study. The questionnaire was designed to collect data regarding demographics (sex and age), general health [weight and height, to calculate body mass index (BMI)], and physical episodes related to gastrointestinal disorders. Diagnosis of dyspepsia and irritable bowel syndrome (IBS) was made according to the Rome III criteria. Gastroesophageal reflux disease (GERD) was defined by episodes of heartburn and/or acid reflux that occurred at least once a week, according to the Montreal definition. RESULTS: Of 2520 students recruited for survey participation, only 1870 (males: 967; age range: 17-32 years, mean age: 21.3 years) returned a completed questionnaire. One hundred and eight (5.67%) of the student participants fit the criteria for dyspepsia diagnosis. Stratification analysis of dyspepsia and non-dyspepsia cases showed no statistically significant differences in age or BMI; however, the prevalence of dyspepsia was significantly higher in women than in men (7.53% vs 4.14%, P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Li,M., Lu,B., Chu,L., Zhou,H., Chen,M.Y.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC3974534
Editors
Dependency of bulk chlorine decay rates on flow velocity in water distribution networks 2003 Menaia, J., LNEC (National Civ. Eng. Laboratory), 1700-066 Lisbon, Portugal
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Water Science and Technology: Water Supply
Periodical, Abbrev.
Water Sc.Technol.Water Supply
Pub Date Free Form
2003/
Volume
3
Issue
2-Jan
Start Page
209
Other Pages
214
Notes
Place of Publication
ISSN/ISBN
1606-9749
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Understanding chlorine residual decay kinetics and the factors that influence them are essential for such current tasks as siting chlorination facilities, dosage optimisation, choice of sampling locations and frequencies, and general design and operational control of drinking water networks, increasingly accomplished with the help of simulation models. Available constants for bulk chlorine decay are typically determined under static conditions. However, as for all fast reactions in water flows, chlorine consumption rates in drinking water pipes may be influenced by the existing mixing regimes, a function of flow turbulence, which is primarily controlled by flow velocity and pipe diameter. Flow velocities vary greatly in space and time in water transmission and distribution systems; pipe diameters are seldom uniform. Although both variables are readily available in the currently available network analysis simulators that implement chlorine models, such variations are not accounted for. Instead, a single preset decay rate constant is generally used for describing chlorine residual consumption throughout an entire system. In addition to highlighting how negligible PVC pipe wall chlorine consumption is, as such, this paper presents experimental evidence of a significant correlation between pipe flow velocity and bulk chlorine decay rates, and proposes a simple but effective approach to implement this dependency in current simulators.
Descriptors
chlorine, drinking water, chlorination, conference paper, correlation analysis, flow rate, fluid intake, kinetics, process control, simulation, tube, turbulent flow, water flow, water sampling, water supply
Links
Book Title
Database
Embase
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Authors
Menaia,J., Coelho,S. T., Lopes,A., Fonte,E., Palma,J.
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