WTS database

Title	Pub Year Sort descending	Author	SearchLink
Cytotoxic effects of BADGE (bisphenol A diglycidyl ether) and BFDGE (bisphenol F diglycidyl ether) on Caco-2 cells in vitro	2006	Microbiology and Biotoxins Area, ANFACO-CECOPESCA, Campus Univ de Vigo, Vigo, Pontevedra, Spain.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Archives of Toxicology Periodical, Abbrev. Arch.Toxicol. Pub Date Free Form Nov Volume 80 Issue 11 Start Page 748 Other Pages 755 Notes LR: 20131121; JID: 0417615; 0 (Actins); 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (bisphenol F diglycidyl ether); 36015-30-2 (Propidium); EC 1.1.1.27 (L-Lactate Dehydrogenase); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); 2006/03/21 [received] Place of Publication Germany ISSN/ISBN 0340-5761; 0340-5761 Accession Number PMID: 16783546 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1007/s00204-006-0121-1 [doi] Output Language Unknown(0) PMID 16783546 Abstract Bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) are used as starting substances for the manufacturing of epoxy resins used in internal can coatings. They are obtained by a condensation reaction between epichlorohydrin with bisphenol A and bisphenol F, respectively. These potential endocrine disrupting chemicals are able to enter the food chain and to reach the intestinal epithelium, causing structural and functional damages. The human colorectal adenocarcinoma cell line Caco-2 is a widely used in vitro model of the intestinal cells. The aim of this study was to characterize BADGE and BFDGE toxicity in Caco-2 cells, in particular, at the cellular and molecular level. Using several approaches, we characterized BADGE- and BFDGE-induced cell toxicity in Caco-2 cells. The treatment was done using different concentrations up to cytotoxic doses and different times of exposure to the agents. We evaluated the effect of these compounds on cell morphology, cell detachment, cell proliferation, F-actin disruption and plasma membrane integrity. Both compounds are able to induce morphological changes, cell detachment from the substratum and to inhibit cell proliferation, being these effects time and dose-dependent. Moreover, BADGE and BFDGE induce F-actin depolymerization, this effect is very potent at 24 h of incubation with the agents and a complete F-actin disruption can be observed at 200 microM BADGE or BFDGE. In addition, cell integrity is not damaged, since neither propidium iodide uptake nor LDH release takes place in Caco-2 cells exposed to high doses of these agents for 24 h. Descriptors Actins/metabolism, Benzhydryl Compounds, Caco-2 Cells, Cell Adhesion/drug effects, Cell Membrane/drug effects/metabolism, Cell Proliferation/drug effects, Cytoskeleton/drug effects, Epoxy Compounds/toxicity, Humans, L-Lactate Dehydrogenase/metabolism, Propidium/metabolism Links Book Title Database Publisher Data Source Authors Ramilo,G., Valverde,I., Lago,J., Vieites,J. M., Cabado,A. G. Original/Translated Title URL Date of Electronic 20060617 PMCID Editors
Role of snus in initiation and cessation of tobacco smoking in Sweden	2006	Institute for Tobacco Studies, Stockholm, Sweden. tobstud@algonet.se	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Jun Volume 15 Issue 3 Start Page 210 Other Pages 214 Notes LR: 20140909; JID: 9209612; OID: NLM: PMC2564662; ppublish Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 16728752 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 15/3/210 [pii] Output Language Unknown(0) PMID 16728752 Abstract OBJECTIVE: To examine patterns of smoking and snus use and identify individual pathways of Swedish tobacco users in order to clarify whether snus use is associated with increased or decreased smoking. METHODS: Retrospective analysis of data from a cross-sectional survey completed by 6752 adult Swedes in 2001-2 focusing on identifying tobacco use history by survey items on current and prior tobacco use and smoking initiation and cessation procedures. RESULTS: 15% of the men and 19% of the women completing the survey were daily smokers. 21% of the men and 2% of the women were daily snus users. Almost all (91%) male daily smoking began before the age of 23 years, whereas initiation of daily snus use continued throughout the age range (33% of initiation after age 22). 20% of male primary snus users started daily smoking compared to 47% of non-primary snus users. Thus, the odds of initiating daily smoking were significantly lower for men who had started using snus than for those who had not (odds ratio (OR) 0.28, 95% confidence interval (CI) 0.22 to 0.36). Among male primary smokers, 28% started secondary daily snus use and 73% did not. 88% of those secondary snus users had ceased daily smoking completely by the time of the survey as compared with 56% of those primary daily smokers who never became daily snus users (OR 5.7, 95% CI 4.9 to 8.1). Among men who made attempts to quit smoking, snus was the most commonly used cessation aid, being used by 24% on their latest quit attempt. Of those men who had used one single cessation aid 58% had used snus, as compared with 38% for all nicotine replacement therapy products together. Among men who used snus as a single aid, 66% succeeded in quitting completely, as compared with 47% of those using nicotine gum (OR 2.2, 95% CI 1.3 to 3.7) or 32% for those using the nicotine patch (OR 4.2, 95% CI 2.1 to 8.6). Women using snus as an aid were also significantly more likely to quit smoking successfully than those using nicotine patches or gum. CONCLUSION: Use of snus in Sweden is associated with a reduced risk of becoming a daily smoker and an increased likelihood of stopping smoking. Descriptors Adolescent, Adult, Age Distribution, Aged, Female, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Sex Distribution, Smoking/epidemiology/prevention & control, Smoking Cessation/methods/statistics & numerical data, Sweden/epidemiology, Tobacco Use Disorder/epidemiology/rehabilitation, Tobacco, Smokeless Links Book Title Database Publisher Data Source Authors Ramstrom,L. M., Foulds,J. Original/Translated Title URL Date of Electronic PMCID PMC2564662 Editors
Air pollution in Boston bars before and after a smoking ban	2006	Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA. repace@comcast.net	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC public health Periodical, Abbrev. BMC Public Health Pub Date Free Form 27-Oct Volume 6 Issue Start Page 266 Other Pages Notes LR: 20140907; JID: 100968562; 0 (Air Pollutants, Occupational); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Tobacco Smoke Pollution); OID: NLM: PMC1637107; 2006/04/28 [received]; 2006/10/27 [accepted]; 2006/10/27 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1471-2458; 1471-2458 Accession Number PMID: 17069654 Language eng SubFile Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 1471-2458-6-266 [pii] Output Language Unknown(0) PMID 17069654 Abstract BACKGROUND: We quantified the air quality benefits of a smoke-free workplace law in Boston Massachusetts, U.S.A., by measuring air pollution from secondhand smoke (SHS) in 7 pubs before and after the law, comparing actual ventilation practices to engineering society (ASHRAE) recommendations, and assessing SHS levels using health and comfort indices. METHODS: We performed real-time measurements of respirable particle (RSP) air pollution and particulate polycyclic aromatic hydrocarbons (PPAH), in 7 pubs and outdoors in a model-based design yielding air exchange rates for RSP removal. We also assessed ventilation rates from carbon dioxide concentrations. We compared RSP air pollution to the federal Air Quality Index (AQI) and the National Ambient Air Quality Standard (NAAQS) to assess health risks, and assessed odor and irritation levels using published SHS-RSP thresholds. RESULTS: Pre-smoking-ban RSP levels in 6 pubs (one pub with a non-SHS air quality problem was excluded) averaged 179 microg/m3, 23 times higher than post-ban levels, which averaged 7.7 microg/m3, exceeding the NAAQS for fine particle pollution (PM2.5) by nearly 4-fold. Pre-smoking ban levels of fine particle air pollution in all 7 of the pubs were in the Unhealthy to Hazardous range of the AQI. In the same 6 pubs, pre-ban indoor carcinogenic PPAH averaged 61.7 ng/m3, nearly 10 times higher than post-ban levels of 6.32 ng/m3. Post-ban particulate air pollution levels were in the Good AQI range, except for 1 venue with a defective gas-fired deep-fat fryer, while post-ban carcinogen levels in all 7 pubs were lower than outdoors. CONCLUSION: During smoking, although pub ventilation rates per occupant were within ASHRAE design parameters for the control of carbon dioxide levels for the number of occupants present, they failed to control SHS carcinogens or RSP. Nonsmokers' SHS odor and irritation sensory thresholds were massively exceeded. Post-ban air pollution measurements showed 90% to 95% reductions in PPAH and RSP respectively, differing little from outdoor concentrations. Ventilation failed to control SHS, leading to increased risk of the diseases of air pollution for nonsmoking workers and patrons. Boston's smoking ban eliminated this risk. Descriptors Air Movements, Air Pollutants, Occupational/analysis, Air Pollution, Indoor/analysis/legislation & jurisprudence/prevention & control, Boston, Environmental Monitoring/methods, Guidelines as Topic, Humans, Occupational Exposure/legislation & jurisprudence/prevention & control, Polycyclic Hydrocarbons, Aromatic/analysis, Program Evaluation, Public Policy, Restaurants/legislation & jurisprudence, Risk Assessment, Smoking/legislation & jurisprudence/prevention & control, Tobacco Smoke Pollution/analysis/legislation & jurisprudence/prevention & control, Ventilation/standards Links Book Title Database Publisher Data Source Authors Repace,J. L., Hyde,J. N., Brugge,D. Original/Translated Title URL Date of Electronic 20061027 PMCID PMC1637107 Editors
Young adult smoker risk perceptions of traditional cigarettes and nontraditional tobacco products	2006		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Am J Health Behav Periodical, Abbrev. Am.J.Health Behav. Pub Date Free Form Volume 30 Issue 3 Start Page 302 Other Pages 12 Notes ID: 16712444 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract OBJECTIVE: To explore risk perceptions of traditional and nontraditional tobacco products (NTPs) among young adult smokers. METHODS: Focus groups with African Americans, non-Hispanic whites, and Hispanics. Risk ratings of light, regular, and menthol cigarettes and of NTPs and marijuana and cigarettes were compared. RESULTS: Participants tended to view light cigarettes as safer than regular cigarettes. Shisha and herbal products were rated as safer than traditional cigarettes, but there were differences in ratings by race/ethnicity, related to preferred cigarette variety. CONCLUSIONS: Health communication messages about the use of cigarettes and NTPs should consider risk perceptions about the products and racial/ethnic differences. Descriptors Attitude to Health, Health Behavior, Marijuana Smoking/adverse effects, Smoking/adverse effects, Tobacco/adverse effects, Adult, African Continental Ancestry Group/psychology, European Continental Ancestry Group/psychology, Exercise/psychology, Focus Groups, Health Knowledge, Attitudes, Practice, Hispanic Americans/psychology, Humans, Marijuana Smoking/epidemiology, Marijuana Smoking/ethnology, Marijuana Smoking/psychology, Risk Assessment, Smoking/epidemiology, Smoking/ethnology, Smoking/psychology, Socioeconomic Factors, Tennessee, Texas Links http://pesquisa.bvsalud.org/ghl/resource/en/mdl-16712444 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Richter,Patricia A., Pederson,Linda L., O'Hegarty,Michelle,M. Original/Translated Title URL Date of Electronic PMCID Editors
A comparison between indoor air quality before and after the implementation of the smoking ban in public places in Italy	2006	Unita funzionale per la prevenzione dei danni da fumo dell'istituto nazionale per lo studio e la cura dei tumori SIMG, Societa italiana di medicina generate, Milano.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Epidemiologia e prevenzione Periodical, Abbrev. Epidemiol.Prev. Pub Date Free Form Nov-Dec Volume 30 Issue 6 Start Page 334 Other Pages 337 Notes JID: 8902507; 0 (Tobacco Smoke Pollution); ppublish Place of Publication Italy ISSN/ISBN 1120-9763; 1120-9763 Accession Number PMID: 17333687 Language ita SubFile Comparative Study; English Abstract; Journal Article; IM DOI 2006/E&P6/E&P6_334_art2.pdf [pii] Output Language Unknown(0) PMID 17333687 Abstract OBJECTIVE: To monitor indoor air quality index in a few Italian hospitality industry venues before and after the implementation of the smoking ban in January 2005. DESIGN: Indoor PM2.5 measurements were carried out in four Milan restaurants during evening hours in the period January-February 2004, and again in January-February 2005, with concurrent outdoor PM2.5 monitoring. The measures were recorded with a portable laser-operated aerosol analyzer with a sampling time of 2 minutes, calibrated by comparison with gravimetric method RESULTS: PM2.5 ranged between 187+/-52 and 709+/-180 mg/m3, and between 24+/-10 e 141+/-28 mg/m3 (p <0.0001) in the years 2004 and 2005, respectively. After the 2005 smoking ban, overall indoor fine particle pollution decreased by values in the range from 81 to 96%. CONCLUSIONS: Within the limits of a small sample, the study showed a good compliance with the smoking ban in the hospitality industry which resulted in a remarkable improvement in air quality index. Smoking ban thus appears to achieve the aims of protecting people from exposure to an unwanted dangerous pollutant such as environmental tobacco smoke. Descriptors Air Pollution, Indoor/analysis/legislation & jurisprudence/prevention & control, Humans, Italy, Occupational Exposure/analysis, Public Facilities/legislation & jurisprudence, Tobacco Smoke Pollution/analysis/legislation & jurisprudence/prevention & control Links Book Title Database Publisher Data Source Authors Ruprecht,A., Boffi,R., Mazza,R., Rossetti,E., De Marco,C., Invernizzi,G. Original/Translated Title Un confronto tra la qualita dell'aria nei luoghi pubblici prima e dopo l'introduzione della legge sull fumo passivo in Italia URL Date of Electronic PMCID Editors
In vitro activity of caspofungin against planktonic and sessile Candida sp. cells	2006	Department of Pharmaceutical Microbiology, Medical University of Lublin, Chodiki 1, 20-093 Lublin, Poland.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Polish journal of microbiology / Polskie Towarzystwo Mikrobiologow = The Polish Society of Microbiologists Periodical, Abbrev. Pol.J.Microbiol. Pub Date Free Form Volume 55 Issue 2 Start Page 133 Other Pages 137 Notes LR: 20121115; JID: 101229003; 0 (Antifungal Agents); 0 (Biocompatible Materials); 0 (Echinocandins); 0 (Peptides, Cyclic); 0 (Silicone Elastomers); F0XDI6ZL63 (caspofungin); ppublish Place of Publication Poland ISSN/ISBN 1733-1331; 1733-1331 Accession Number PMID: 17419291 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI Output Language Unknown(0) PMID 17419291 Abstract Candida sp. may be regarded as one of the leading etiologic agents of hospital-acquired infections, including those related with the indwelling medical devices, which become colonized by the yeasts, accompanied by biofilm formation. In this paper we assayed in vitro susceptibility to caspofungin of planktonic and sessile cells of nasopharyngeal isolates of Candida sp. Two types of biomaterials were used - silicone elastomer-coated latex urinary Foley catheter and PCV Thorax catheter. The minimal inhibitory concentrations (MIC) of caspofungin for planktonic Candida sp. cells ranged from 0.008 to 0.031 mg/l, while the minimal fungicidal concentrations (MFC) from 0.008 to 0.062 mg/l, with MFC/MIC ratios 8 mg/l). In all cases, drug concentrations depended on the strain and the biomaterial used. Our preliminary data suggest that caspofungin, showing good anti-adherent activity in vitro against Candida sp., appears to be a potential agent rather for prophylaxis of the yeast infections associated with biomaterials but not for their treatment. Descriptors Antifungal Agents/pharmacology, Biocompatible Materials, Biofilms/drug effects, Candida/drug effects, Cross Infection/prevention & control, Echinocandins, Humans, Microbial Sensitivity Tests/methods, Peptides, Cyclic/pharmacology, Silicone Elastomers Links Book Title Database Publisher Data Source Authors Serefko,A., Chudzik,B., Malm,A. Original/Translated Title URL Date of Electronic PMCID Editors
A closed-loop control "playback" smoking machine for generating mainstream smoke aerosols	2006	Shihadeh, A., Aerosol Research Laboratory, Department of Mechanical Engineering, American University of Beirut, Beirut, Lebanon	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung Periodical, Abbrev. J.Aerosol Med.Deposition Clear.Eff.Lung Pub Date Free Form 2006/ Volume 19 Issue 2 Start Page 137 Other Pages 147 Notes Place of Publication ISSN/ISBN 0894-2684 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract A first generation smoking machine capable of reading and replicating detailed puffing behavior from recorded smoking topography data is presented. Unlike standard smoking machines, which model human puffing behavior as a steady periodic waveform with a fixed puff frequency, volume, and duration, this novel machine generates a mainstream smoke aerosol by automatically "playing-back" puff topography recordings. Because combustion chemistry is highly non-linear, representing real smoking behavior with a smoothed periodic waveform may result in a tobacco smoke aerosol with a significantly different chemical composition and physical properties than that generated by a smoker. The machine presented here utilizes a rapid closed-loop control algorithm coded in LabviewÂ® to generate smoke aerosols for toxicological assessment and inhalation studies. To illustrate its use, dry particulate matter and carbon monoxide yields generated using the playback and equivalent periodic puffing regimens are compared for a single smoking session by a 26-year-old male narghile water-pipe smoker. It was found that the periodic puffing regimen yielded 20% less carbon monoxide (CO) than the played-back smoking session, indicating that steady periodic smoking regimens, which are widely used in tobacco smoke research, may not produce realistic smoke aerosols. Â© Mary Ann Liebert, Inc. Descriptors carbon monoxide, cigarette smoke, closed loop control, tobacco smoke, unclassified drug, water, accuracy, aerosol, algorithm, devices, article, combustion, control system, inhalation, machine, measurement, particulate matter, recording, smoking, smoking machine, tube, waveform, Labview Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Shihadeh,A., Azar,S. Original/Translated Title URL Date of Electronic PMCID Editors
Tobacco smoking among the first-year medical students	2006	Klinika Alergologii Akademii Medycznej w Gdansku, Poland.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Pneumonologia i alergologia polska Periodical, Abbrev. Pneumonol.Alergol.Pol. Pub Date Free Form Volume 74 Issue 4 Start Page 377 Other Pages 382 Notes LR: 20151119; JID: 9302892; 0 (Tobacco Smoke Pollution); ppublish Place of Publication Poland ISSN/ISBN 0867-7077; 0867-7077 Accession Number PMID: 17427146 Language pol SubFile English Abstract; Journal Article; IM DOI Output Language Unknown(0) PMID 17427146 Abstract The studies have shown that despite studying medicine the rate of tobacco smokers among students is still high. Moreover, in Poland the incidence of smoking is increasing among the youngsters. The study was designed to assess the rate of smokers among the first-year students of two consecutive courses at the Medical University of Gdansk and define their attitudes towards tobacco smoking. The voluntary, multiple-choice questionnaires were distributed among 412 students. The rate of response was 100%. Twenty one percent of responders were current smokers (17% females and 28% men), whereas 7% declared previous smoking. There was no correlation between incidence of smoking among students and their parents (p=0.11). 61% of smokers declared the will to give up their habit and of those 94% were aware of the negative impact of cigarettes on their health. In the group which did not declare the will to quit smoking only 75% knew what the impact of cigarettes on their health was; p=0.02. Only 23% of smokers considered anti-nicotine therapy effective. Almost a half of smokers considered nicotine replacement therapy ineffective for them in quitting cigarette smoking. CONCLUSION: The rate of smokers among the first-year medical students is lower than in general population, but it is still relatively high. However more than a half of smokers wants to give up their habit. Of those who are not willing to, 25% is not aware of the cigarettes' impact on their health. These results call for further anti-nicotine actions. Descriptors Adult, Attitude to Health, Female, Health Education, Humans, Male, Poland/epidemiology, Prevalence, Sex Distribution, Smoking/epidemiology/prevention & control/psychology, Socioeconomic Factors, Students, Medical/psychology/statistics & numerical data, Surveys and Questionnaires, Tobacco Smoke Pollution/statistics & numerical data, Tobacco Use Disorder/epidemiology/prevention & control/psychology, Universities Links Book Title Database Publisher Data Source Authors Sieminska,A., Jassem,J. M., Uherek,M., Wilanowski,T., Nowak,R., Jassem,E. Original/Translated Title Postawy wobec palenia tytoniu wsrod studentow pierwszego roku medycyny URL Date of Electronic PMCID Editors
Effect of temperature and pipe material on biofilm formation and survival of Escherichia coli in used dinking water pipes: A laboratory-based study	2006	Silhan, J., Institute of Environment and Resources, Technical University of Denmark, 2800 Lyngby, Denmark	Read more...
Source Type Print(0) Ref Type Generic Periodical, Full Water Science and Technology Periodical, Abbrev. Water Sci. Technol. Pub Date Free Form 2006/ Volume 54 Issue 3 Start Page 49 Other Pages 56 Notes Place of Publication ISSN/ISBN 0273-1223 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Segments of used drinking water pipes of galvanised steel (GS), cross-linked polyethylene (PEX), copper pipes (Cu) or new medium-density polyethylene (PE) were investigated for the formation of biofilm and survival of E. coli in biofilm and in the water phase. Pipes were filled with water and incubated at 15Â°C or 35Â°C under static conditions. Biofilm formation was followed during 32, 40 and 56 (58) d. The most dense biofilm was formed on GS, reaching approximately 4.7 Ã— 105 CFU/ cm2 measured as heterotrophic plate count (HPC), and at the other materials the density reached 3 Ã— 103CFU/cm2 on PE and PEX and 5 Ã— 101 and 5 Ã— 102 CFU/cm2 on Cu pipes after 58 d at 15Â°C. Biofilm HPC values were higher at 35Â°C than at 15Â°C, with only slightly higher values on the metals, but 100-fold higher on PE and PEX. Adenosine triphosphate (ATP) measurements confirmed the general trends observed by HPC. Higher temperature was seen to be an important factor reducing E. coli survival in the water phase in drinking water pipes. At 15Â°C E. coli survived more than 4 d in GS and Cu pipes and 8 d in PE pipes, but was not detected after 48 h at 35Â°C. The E. coli survived longer at both temperatures in the glass control bottles than in the drinking water pipes. Despite the obvious biofilm formation, E coli was not detected in the biofilm at any of the investigated surfaces. Â© IWA Publishing 2006. Descriptors adenosine triphosphate, copper, drinking water, polyethylene, steel, article, bacterial count, bacterial survival, biofilm, controlled study, Escherichia coli, heterotrophy, high temperature, incubation temperature, laboratory test, nonhuman, pipeline, temperature dependence, water contamination, water supply Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Silhan,J., Corfitzen,C. B., Albrechtsen,H. J. Original/Translated Title URL Date of Electronic PMCID Editors
Epidemiological investigation of an outbreak of viral hepatitis	2006	Singh, P.M.P., Station Health Organisation, Devlali, India	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Medical Journal Armed Forces India Periodical, Abbrev. Med.J.Armed Forces India Pub Date Free Form 2006/10 Volume 62 Issue 4 Start Page 332 Other Pages 334 Notes Place of Publication ISSN/ISBN 0377-1237; 0377-1237 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Background: There was a rise in the number of viral hepatitis cases in a regimental training centre in Mar 2003 and an epidemic of viral hepatitis was suspected. Methods: The clinical case sheets and preliminary investigations carried out in the local military hospital (MH) were reviewed. A cross sectional descriptive epidemiological study was undertaken with survey odf the suspected sewage and water pipelines. Results: A total of 36 cases occurred from Mar 2003 to Apr 2003. There was clustering in time and space suggesting common source epidemic. All the 36 serum samples tested for IgM anti HEV antibodies were positive. Exploration of the water pipelines revealed sewage contamination due to leakage in the pipeline passing close to the sewage line. The overall attack rate was 1.44%. Conclusion: The outbreak of viral hepatitis in the regimental training centre occurred due to sewage contamination of drinking water pipeline. Descriptors drinking water, hepatitis E antigen, immunoglobulin M antibody, antibody detection, article, blood sampling, descriptive research, epidemic, human, medical record review, pipeline, public hospital, sewage, time series analysis, viral contamination, virus hepatitis, water contamination, water supply Links Book Title Database Embase Publisher Data Source Embase Authors Singh,P. M. P., Handa,B. S. K., Banerjee,A. Original/Translated Title URL http://medind.nic.in/maa/t06/i4/maat06i4p332.pdf Date of Electronic PMCID Editors

E-mail