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t-3-Benzyl-r-2,c-6-bis-(4-methoxy-phen-yl)piperidin-4-one oxime 2008
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Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
7-Jun
Volume
64
Issue
Pt 7
Start Page
o1211
Other Pages
Notes
LR: 20111209; JID: 101089178; OID: NLM: PMC2961741; 2008/05/28 [received]; 2008/05/29 [accepted]; 2008/06/07 [epublish]; epublish
Place of Publication
England
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 21202850
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536808016449 [doi]
Output Language
Unknown(0)
PMID
21202850
Abstract
In the title mol-ecule, C(26)H(28)N(2)O(3), the piperidine ring adopts a chair conformation. The two methoxy-phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations, and make a dihedral angle of 80.72 (15) degrees . The benzyl group at position 3 has an equatorial orientation. The oxime group at position 4 has a bi-sectional orientation. The ring of the benzyl group makes dihedral angles of 64.71 (16) and 84.79 (17) degrees with the two benzene rings. Mol-ecules are linked by inter-molecular N-Hcdots, three dots, centeredO, O-Hcdots, three dots, centeredN and C-Hcdots, three dots, centeredO hydrogen bonds, and C-Hcdots, three dots, centeredpi inter-actions. There is also a C-Hcdots, three dots, centeredO intra-molecular inter-action.
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Data Source
Authors
Jayabharathi,J., Thangamani,A., Balamurugan,S., Thiruvalluvar,A., Linden,A.
Original/Translated Title
URL
Date of Electronic
20080607
PMCID
PMC2961741
Editors
Systematic review on international practices in controlling waterpipe tobacco smoking 2015 Institute for Public Health, Ministry of Health, Malaysia E-mail : helentee.gh@moh.gov.my.
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Print(0)
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Journal Article
Periodical, Full
Asian Pacific journal of cancer prevention : APJCP
Periodical, Abbrev.
Asian Pac.J.Cancer.Prev.
Pub Date Free Form
Volume
16
Issue
9
Start Page
3659
Other Pages
3665
Notes
JID: 101130625; 0 (Tobacco Smoke Pollution); ppublish
Place of Publication
Thailand
ISSN/ISBN
1513-7368; 1513-7368
Accession Number
PMID: 25987018
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Review; IM
DOI
Output Language
Unknown(0)
PMID
25987018
Abstract
BACKGROUND: Waterpipe tobacco smoking has becoming popular especially among young people worldwide. Smokers are attracted by its sweeter, smoother smoke, social ambience and the misconception of reduced harm. The objective of this study was to systematically review the effects of waterpipe tobacco policies and practices in reducing its prevalence. MATERIALS AND METHODS: A systematic review was conducted electronically using the PubMed, OVID, Science Direct, Proquest and Embase databases. All possible studies from 1980 to 2013 were initially screened based on titles and abstracts. The selected articles were subjected to data extraction and quality rating. RESULTS: Three studies met the inclusion criteria and were eligible for this review. Almost all of the waterpipe tobacco products and its accessories did not comply with the regulations on health warning labelling practices as stipulated under Article 11 of WHO FCTC. In addition, the grisly new warning labels for cigarettes introduced by Food and Drug Administration did not affect hookah tobacco smoking generally. Indoor air quality in smoking lounges was found to be poor and some hookah lounges were operated without smoke shop certification. CONCLUSIONS: Our findings revealed the availability of minimal information on the practices in controlling waterpipe smoking in reducing its prevalence. The lack of comprehensive legislations or practices in controlling waterpipe smoking warrants further research and policy initiatives to curb this burgeoning global epidemic, especially among the vulnerable younger population.
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Authors
Tee,G.H., Hairi,N.N., Nordin,F., Choo,W.Y., Chan,Y.Y., Kaur,G., Veerasingam,P.D., Bulgiba,A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Systematic Review of Smoking Initiation among Asian Adolescents, 20052015: Utilizing the Frameworks of Triadic Influence and Planned Behavior 2016 Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah (PAPRSB) Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam Email : 14h8402@ubd.edu.bn.
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Print(0)
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Journal Article
Periodical, Full
Asian Pacific journal of cancer prevention : APJCP
Periodical, Abbrev.
Asian Pac.J.Cancer.Prev.
Pub Date Free Form
Volume
17
Issue
7
Start Page
3341
Other Pages
3355
Notes
JID: 101130625; ppublish
Place of Publication
Thailand
ISSN/ISBN
1513-7368; 1513-7368
Accession Number
PMID: 27509974
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
27509974
Abstract
BACKGROUND: A recent WHO data report on mortality attributable to tobacco use including cigarette smoking indicated a very high burden of deaths in Asia and that people often initiate smoking as early as young adolescents. The objectives of this study were to systematically review peerreviewed articles on cigarette smoking initiation among Asian adolescents and to develop a conceptual model of factors influencing smoking initiation by integrating all relevant factors based on existing data. MATERIALS AND METHODS: Following a PRISMA guideline, a systematic review of articles published between 2005 and June 2015 was conducted using 5 databases on cigarette smoking initiation among adolescents (aged 1019 years) living in Asia. We summarized the main findings of each study according to our research questions and data that emerged during the data extraction process. Analysis and categorization were based on the TTI and TPB models and classification of factors extracted from the study, were as follows: personal factors, social factors, broader environmental factors, mediators, and intention to initiate smoking and smoking behavior. RESULTS: Of 1,227 identified studies, only 20 were included in this review. Our findings found that the mean age of cigarette smoking initiation ranged from 10 to 14 years and those who are more likely to initiate smoking are male, older adolescents, adolescents with low parental SES, individuals with low parental monitoring, low parental education level and having no discussion on smoking at home, those living in public housing and those exhibiting healthrisk behavior. Our study also revealed that the risk of smoking initiation increased when they are exposed to smokers, influenced by peers, exposed to tobacco advertisements, receive pocket money, have lack of knowledge about smoking, have poor school performance, have a family conflict and have psychological problems. The conceptual model developed demonstrated complex networks of factors influencing initiation. CONCLUSIONS: This systematic review presents various factors influencing smoking initiation of the Asian adolescents and provides a conceptual framework to further analyze factors. Future studies should have a standard measure of smoking initiation, should analyze interactions and the intensity of relationships between different factors or variables in the conceptual model. This will in turn consolidate the understanding of the different factors affecting smoking initiation and will help to improve interventions in this area.
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Data Source
Authors
Talip,T., Murang,Z., Kifli,N., Naing,L.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Systematic review of health communication for non-cigarette tobacco products 2019
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Print(0)
Ref Type
Journal Article
Periodical, Full
Health communication
Periodical, Abbrev.
Health Commun.
Pub Date Free Form
Volume
34
Issue
3
Start Page
361
Other Pages
369
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
Taylor & Francis
Data Source
google
Authors
Cornacchione Ross, Jennifer, Noar, Seth M, Sutfin, Erin L
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Systematic review of health communication for non-cigarette tobacco products 2019
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Health communication
Periodical, Abbrev.
Health Commun.
Pub Date Free Form
Volume
34
Issue
3
Start Page
361
Other Pages
369
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
Taylor & Francis
Data Source
google
Authors
Cornacchione Ross, Jennifer, Noar, Seth M, Sutfin, Erin L
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Systematic Review and Meta-Analysis of Inhaled Toxicants from Waterpipe and Cigarette Smoking 2016
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Public Health Rep
Periodical, Abbrev.
Public Health Rep.
Pub Date Free Form
Volume
131
Issue
1
Start Page
76
Other Pages
85
Notes
ID: 26843673
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
OBJECTIVE: Waterpipe tobacco smoking (WTS) is an emerging trend worldwide. To inform public health policy and educational programming, we systematically reviewed the biomedical literature to compute the inhaled smoke volume, nicotine, tar, and carbon monoxide (CO) associated with a single WTS session and a single cigarette. METHODS: We searched seven biomedical bibliographic databases for controlled laboratory or natural environment studies designed to mimic human tobacco consumption. Included studies quantified the mainstream smoke of a single cigarette and/or single WTS session for smoke volume, nicotine, tar, and/or CO. We conducted meta-analyses to calculate summary estimates for the inhalation of each unique substance for each mode of tobacco consumption. We assessed between-study heterogeneity using chi-squared and I-squared statistics. RESULTS: Sufficient data from 17 studies were available to derive pooled estimates for inhalation of each exposure via each smoking method. Two researchers working independently abstracted measurement of smoke volume in liters, and nicotine, tar, and CO in milligrams. All numbers included in meta-analyses matched precisely between the two researchers (100% agreement, Cohen's k=1.00). Whereas one WTS session was associated with 74.1 liters of smoke inhalation (95% confidence interval CI] 38.2, 110.0), one cigarette was associated with 0.6 liters of smoke (95% CI 0.5, 0.7). One WTS session was also associated with higher levels of nicotine, tar, and CO. CONCLUSIONS: One WTS session consistently exposed users to larger smoke volumes and higher levels of tobacco toxicants compared with one cigarette. These computed estimates may be valuable to emphasize in prevention programming.
Descriptors
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http://pesquisa.bvsalud.org/ghl/resource/en/mdl-26843673
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Primack,Brian A., Carroll,Mary V., Weiss,Patricia M., Shihadeh,Alan L., Shensa,Ariel, Farley,Steven T., Fine,Michael J., Eissenberg,Thomas, Nayak,Smita
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Synthetic Cannabinoid Use and Descriptive Norms among Collegiate Student-Athletes 2016
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
J Psychoactive Drugs
Periodical, Abbrev.
J.Psychoactive Drugs
Pub Date Free Form
Volume
48
Issue
3
Start Page
166
Other Pages
72
Notes
ID: 27224428
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Synthetic cannabinoids have gained popularity over the past decade, especially among young adults, due to sharing similar psychoactive properties with Tetrahydrocannabinol (THC). A limited number of studies have examined synthetic cannabinoid use among college students but none have examined use exclusively by collegiate student-athletes. The objective of this study was to examine synthetic cannabinoid use among collegiate student-athletes. In the spring of 2013, 3,276 freshmen and transfer collegiate student-athletes from 47 NCAA Division I, II, and III institutions participated in a web-based survey on substance use. Bivariate logistic regression was used to analyze the relationship between collegiate student-athlete characteristics, substance use, and descriptive norms with lifetime use of synthetic cannabinoids. Sixty-two individuals (1.9%) reported lifetime use of synthetic cannabinoids, and 3 (0.1%) reported past-30-day use. Males, current drinkers, and athletes who used hookah and marijuana in the past 30 days were more likely to use synthetic cannabinoids. Peer use of synthetic cannabinoids was estimated to be higher than actual use, and such overestimation was positively associated with personal use of synthetic cannabinoids. Our findings suggest that campaigns addressing normative beliefs should be implemented on college campuses to prevent synthetic cannabinoid use among college students and collegiate student-athletes.
Descriptors
Links
http://dx.doi.org/10.1080/02791072.2016.1186305
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Egan,Kathleen L., Erausquin,Jennifer Toller, Milroy,Jeffrey J., Wyrick,David L.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Syngonanthus nitens Bong. (Rhul.)-Loaded Nanostructured System for Vulvovaginal Candidiasis Treatment 2016 Department of Biological Sciences, School of Pharmaceutical Sciences, UNESP-Univ Estadual Paulista, Araraquara, Sao Paulo 14800-903, Brazil. matheusramos_91@hotmail.com.; Department of Biological Sciences, School of Pharmaceutical Sciences, UNESP-Univ Est
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Print(0)
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Journal Article
Periodical, Full
International journal of molecular sciences
Periodical, Abbrev.
Int.J.Mol.Sci.
Pub Date Free Form
22-Aug
Volume
17
Issue
8
Start Page
E1368
Other Pages
Notes
LR: 20160824; JID: 101092791; OTO: NOTNLM; 2016/05/24 [received]; 2016/06/28 [revised]; 2016/06/30 [accepted]; epublish
Place of Publication
ISSN/ISBN
1422-0067; 1422-0067
Accession Number
PMID: 27556451
Language
ENG
SubFile
JOURNAL ARTICLE
DOI
E1368 [pii]
Output Language
Unknown(0)
PMID
27556451
Abstract
Herbal-loaded drug delivery nanotechnological systems have been extensively studied recently. The antimicrobial activity of medicinal plants has shown better pharmacological action when such plants are loaded into a drug delivery system than when they are not loaded. Syngonanthus nitens Bong. (Rhul.) belongs to the Eriocaulaceae family and presents antiulcerogenic, antioxidant, antibacterial, and antifungal activity. The aim of this study was to evaluate the antifungal activity of Syngonanthus nitens (S. nitens) extract that was not loaded (E) or loaded (SE) into a liquid crystal precursor system (S) for the treatment of vulvovaginal candidiasis (VVC) with Candida albicans. The minimal inhibitory concentration (MIC) was determined by the microdilution technique. Additionally, we performed hyphae inhibition and biofilm tests. Finally, experimental candidiasis was evaluated in in vivo models with Wistar female rats. The results showed effective antifungal activity after incorporation into S for all strains tested, with MICs ranging from 31.2 to 62.5 mug/mL. Microscopic observation of SE revealed an absence of filamentous cells 24 h of exposure to a concentration of 31.2 mug/mL. E demonstrated no effective action against biofilms, though SE showed inhibition against biofilms of all strains. In the in vivo experiment, SE was effective in the treatment of infection after only two days of treatment and was more effective than E and amphotericin B. The S. nitens is active against Candida albicans (C. albicans) and the antifungal potential is being enhanced after incorporation into liquid crystal precursor systems (LCPS). These findings represent a promising application of SE in the treatment of VVC.
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Database
Publisher
Data Source
Authors
Dos Santos Ramos,M.A., de Toledo,L.G., Calixto,G.M., Bonifacio,B.V., de Freitas Araujo,M.G., Dos Santos,L.C., de Almeida,M.T., Chorilli,M., Bauab,T.M.
Original/Translated Title
URL
Date of Electronic
20160822
PMCID
Editors
Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms 2014 BIOPEP Peptide Group, Department of Biochemistry, Science Faculty, University of Stellenbosch, Stellenbosch, South Africa.; BIOPEP Peptide Group, Department of Biochemistry, Science Faculty, University of Stellenbosch, Stellenbosch, South Africa.; Centre
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Print(0)
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Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
Jul
Volume
58
Issue
7
Start Page
3697
Other Pages
3707
Notes
LR: 20150113; CI: Copyright (c) 2014; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Peptides); 0 (Reactive Oxygen Species); 0 (Tyrocidine); 7XU7A7DROE (Amphotericin B); F0XDI6ZL63 (caspofungin); OID: NLM: PMC4068576; 2014/04/21 [aheadofprint]
Place of Publication
United States
ISSN/ISBN
1098-6596; 0066-4804
Accession Number
PMID: 24752256
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1128/AAC.02381-14 [doi]
Output Language
Unknown(0)
PMID
24752256
Abstract
Tyrocidines are cationic cyclodecapeptides from Bacillus aneurinolyticus that are characterized by potent antibacterial and antimalarial activities. In this study, we show that various tyrocidines have significant activity against planktonic Candida albicans in the low-micromolar range. These tyrocidines also prevented C. albicans biofilm formation in vitro. Studies with the membrane-impermeable dye propidium iodide showed that the tyrocidines disrupt the membrane integrity of mature C. albicans biofilm cells. This membrane activity correlated with the permeabilization and rapid lysis of model fungal membranes containing phosphatidylcholine and ergosterol (70:30 ratio) induced by the tyrocidines. The tyrocidines exhibited pronounced synergistic biofilm-eradicating activity in combination with two key antifungal drugs, amphotericin B and caspofungin. Using a Caenorhabditis elegans infection model, we found that tyrocidine A potentiated the activity of caspofungin. Therefore, tyrocidines are promising candidates for further research as antifungal drugs and as agents for combinatorial treatment.
Descriptors
Links
Book Title
Database
Publisher
American Society for Microbiology. All Rights Reserved
Data Source
Authors
Troskie,A.M., Rautenbach,M., Delattin,N., Vosloo,J.A., Dathe,M., Cammue,B.P., Thevissen,K.
Original/Translated Title
URL
Date of Electronic
20140421
PMCID
PMC4068576
Editors
Synergism in biofilm formation between Salmonella enteritidis and a nitrogen-fixing strain of Klebsiella pneumoniae 1997 Jones, K., Division of Biological Sciences, IEBS, Lancaster University, Lancaster LA1 4YQ, United Kingdom
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of applied microbiology
Periodical, Abbrev.
J.Appl.Microbiol.
Pub Date Free Form
1997/
Volume
82
Issue
5
Start Page
663
Other Pages
668
Notes
Place of Publication
ISSN/ISBN
1364-5072
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
A laboratory reactor, which simulates biofilm formation in water pipes, was used to study interactions in biofilm formation between a nitrogen-fixing strain of Klebsiella pneumoniae and Salmonella enteritidis. The level of attachment of Salm. enteritidis was higher in the binary biofilm than in the single species biofilm. In the initial colonization phase the binary biofilm contained a much higher proportion of metabolically active cells than in single species biofilms formed by either Salm. enteritidis or Kl. pneumoniae. When a pulse of Salm. enteritidis was passed over an already established biofilm of Kl. pneumoniae it rapidly became integrated into the biofilm, from where it was subsequently released into the water column, along with Kl. pneumoniae. Klebsiella pneumoniae fixed nitrogen in the presence of Salm. enteritidis in both types of biofilm.
Descriptors
nitrogen, article, biofilm, controlled study, Klebsiella pneumoniae, nitrogen fixation, nonhuman, Salmonella enterica serovar Enteritidis, water supply
Links
Book Title
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
Jones,K., Bradshaw,S. B.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors