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High frequency of virulence genes among Escherichia coli with the blaCTX-M genotype from diarrheic piglets in China 2015 College of Veterinary Medicine, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University (SCAU), Guangzhou 510642, China.; College of Veterinary Medicine, Guangdong Provincial K
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Veterinary microbiology
Periodical, Abbrev.
Vet.Microbiol.
Pub Date Free Form
18-Nov
Volume
180
Issue
4-Mar
Start Page
260
Other Pages
267
Notes
CI: Copyright (c) 2015; JID: 7705469; 0 (Escherichia coli Proteins); EC 3.5.2.6 (beta-Lactamases); EC 3.5.2.6 (beta-lactamase CTX-M, E coli); OTO: NOTNLM; 2015/05/28 [received]; 2015/08/12 [revised]; 2015/08/26 [accepted]; 2015/09/15 [aheadofprint]; ppubl
Place of Publication
Netherlands
ISSN/ISBN
1873-2542; 0378-1135
Accession Number
PMID: 26385248
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.vetmic.2015.08.017 [doi]
Output Language
Unknown(0)
PMID
26385248
Abstract
The purpose of this study was to characterize the virulence potential and determine the molecular epidemiology of extended-spectrum beta-lactamases (ESBLs) in CTX-M-producing Escherichia coli isolated from piglets with diarrhea in China. A total of 62 E. coli isolates were obtained among which 49 and 13 were collected from diarrheic and healthy piglets, respectively. Cefotaxime resistant strains were screened for the presence of ESBL, adhesin and exotoxin genes as well as for their biofilm-forming ability. Characterization of blaCTX-M plasmids was determined by conjugation along with the determination of genetic relatedness and plasmid replicon type. CTX-M producers were found in 36 isolates with 6 different subtypes: blaCTX-M-14,27,65 from CTX-M-9G (n=27) and blaCTX-M-55, 15,79 from CTX-M-1G (n=22). This also included 13 isolates that carried two different CTX-M genes. Thirty of 36 CTX-M producers and 12 of 13 multiple CTX-M alleles were confirmed from diarrheic piglets. The presence of the iron regulatory gene irp2 as well as EAST1 was found in 83.3% (25/30) of CTX-M-producing isolates from diarrheic piglets and these were significantly better biofilm formers. PFGE profiles of CTX-M-positive isolates indicated the spread of multidrug resistance was primarily horizontal and spread via transferable plasmids. Most blaCTX-M-9G genes (10/17) were located on the IncFIB type plasmid with sizes of 40-145 kb, while the blaCTX-M-1G (11/16) genes were located on the approximately 100 kb IncN-type plasmid. Together, our findings demonstrate that CTX-M ESBL-producing E. coli from diarrheic piglets were associated with serious multidrug resistance, increased biofilm-forming ability and the irp2 gene of HPI. Our findings highlight the need to urgent control the spread of resistant strains through food chain.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Zhang,W.H., Ren,S.Q., Gu,X.X., Li,W., Yang,L., Zeng,Z.L., Liu,Y.H., Jiang,H.X.
Original/Translated Title
URL
Date of Electronic
20150915
PMCID
Editors
Sustained Waterpipe Tobacco Smoking and Trends Over Time 2015 Center for Research on Media, Technology, and Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of General Internal Medicine, School of Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of Ad
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Preventive Medicine
Periodical, Abbrev.
Am.J.Prev.Med.
Pub Date Free Form
Dec
Volume
49
Issue
6
Start Page
859
Other Pages
867
Notes
LR: 20160311; CI: Copyright (c) 2015; GR: R01 CA140150/CA/NCI NIH HHS/United States; GR: R01 DA001411/DA/NIDA NIH HHS/United States; GR: R01 DA001411/DA/NIDA NIH HHS/United States; GR: R01-CA140150/CA/NCI NIH HHS/United States; JID: 8704773; NIHMS764052;
Place of Publication
Netherlands
ISSN/ISBN
1873-2607; 0749-3797
Accession Number
PMID: 26385163
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.amepre.2015.06.030 [doi]
Output Language
Unknown(0)
PMID
26385163
Abstract
INTRODUCTION: Use of waterpipe tobacco smoking (WTS) is now prevalent among U.S. adolescents. However, the more clinically relevant questions are whether users exhibit sustained patterns of use and whether use is increasing over time relative to other tobacco products. We aimed to examine factors associated with sustained WTS among U.S. adolescents and to compare prevalence trends between WTS and other tobacco products. METHODS: The Monitoring the Future project began assessing WTS among 12th-grade students in 2010. In 2014, we conducted multivariable regression analyses to examine correlates of sustained WTS, which we defined as use at least six times in the past 12 months. We used trend analysis to compare use of WTS and other types of tobacco. RESULTS: Of the 8,737 participants queried from 2010 to 2013, 18.8% (1,639) reported past-year WTS, whereas 7.2% (627) reported sustained use. Sustained WTS was inversely associated with female sex (versus male, OR=0.78, 95% CI=0.63, 0.96); African American race (versus Caucasian, OR=0.26, 95% CI=0.14, 0.48); and increased number of parents in the home (p
Descriptors
Links
Book Title
Database
Publisher
American Journal of Preventive Medicine. Published by Elsevier Inc
Data Source
Authors
Primack,B.A., Freedman-Doan,P., Sidani,J.E., Rosen,D., Shensa,A., James,A.E., Wallace,J.
Original/Translated Title
URL
Date of Electronic
20150915
PMCID
PMC4780332
Editors
Validation of the Waterpipe Tolerance Questionnaire Among Jordanian School-Going Adolescent Waterpipe Users 2015 The Hashemite University. sukaina-alzyoud@hu.edu.jo.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Global journal of health science
Periodical, Abbrev.
Glob.J.Health.Sci.
Pub Date Free Form
25-Jun
Volume
8
Issue
2
Start Page
198
Other Pages
208
Notes
LR: 20160819; JID: 101519495; OID: NLM: PMC4804001; 2015/02/26 [received]; 2015/03/17 [accepted]; epublish
Place of Publication
Canada
ISSN/ISBN
1916-9736; 1916-9736
Accession Number
PMID: 26383198
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Validation Studies; IM
DOI
10.5539/gjhs.v8n2p198 [doi]
Output Language
Unknown(0)
PMID
26383198
Abstract
INTRODUCTION: Waterpipe use among adolescents has been increasing progressively. Yet no studies were reported to assess the validity and reliability of nicotine dependence scale. The current study aims to assess the validity and reliability of an Arabic version of the modified Waterpipe Tolerance Questionnaire WTQ among school-going adolescent waterpipe users. METHODS: In a cross-sectional study conducted in Jordan, information on waterpipe use among 333 school-going adolescents aged 11-18 years was obtained using the Arabic version of the WTQ. An exploratory factor analysis and correlation matrices were conducted to assess validity and reliability of the WTQ. RESULTS: The WTQ had a 0.73 alpha of internal consistency indicating moderate level of reliability. The scale showed multidimensionality with items loading on two factors, namely waterpipe consumption and morning smoking. CONCLUSION: This study report nicotine dependence level among school-going adolescents who identify themselves as waterpipe users using the WTQ.
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Database
Publisher
Data Source
Authors
Alzyoud,S., Veeranki,S.P., Kheirallah,K.A., Shotar,A.M., Pbert,L.
Original/Translated Title
URL
Date of Electronic
20150625
PMCID
PMC4804001
Editors
Primo-Vascular System as Presented by Bong Han Kim 2015 Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn, AL 36849, USA ; School of Kinesiology, Auburn University, Auburn, AL 36849, USA ; Edward Via College of Osteopathic Medicine, Auburn, AL 36849, USA.; Department of
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Evidence-based complementary and alternative medicine : eCAM
Periodical, Abbrev.
Evid Based.Complement.Alternat Med.
Pub Date Free Form
Volume
2015
Issue
Start Page
361974
Other Pages
Notes
LR: 20150919; JID: 101215021; OID: NLM: PMC4562093; 2014/09/29 [received]; 2015/01/01 [revised]; 2015/01/05 [accepted]; 2015/08/25 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
1741-427X; 1741-427X
Accession Number
PMID: 26379743
Language
eng
SubFile
Journal Article; Review
DOI
10.1155/2015/361974 [doi]
Output Language
Unknown(0)
PMID
26379743
Abstract
In the 1960s Bong Han Kim discovered and characterized a new vascular system. He was able to differentiate it clearly from vascular blood and lymph systems by the use of a variety of methods, which were available to him in the mid-20th century. He gave detailed characterization of the system and created comprehensive diagrams and photographs in his publications. He demonstrated that this system is composed of nodes and vessels, and it was responsible for tissue regeneration. However, he did not disclose in detail his methods. Consequently, his results are relatively obscure from the vantage point of contemporary scientists. The stains that Kim used had been perfected and had been in use for more than 100 years. Therefore, the names of the stains were directed to the explicit protocols for the usage with the particular cells or molecules. Traditionally, it was not normally necessary to describe the method used unless it is significantly deviated from the original method. In this present work, we have been able to disclose staining methods used by Kim.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Vodyanoy,V., Pustovyy,O., Globa,L., Sorokulova,I.
Original/Translated Title
URL
Date of Electronic
20150825
PMCID
PMC4562093
Editors
A newly identified susceptibility locus near FOXP1 modifies the association of gastroesophageal reflux with Barrett's esophagus 2015 Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Biostatistics, University of Washington, School of Public Health, Seattle, Washington. jdai@fredhutch.org tvaughan@u.washington.edu.; Division o
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Periodical, Abbrev.
Cancer Epidemiol.Biomarkers Prev.
Pub Date Free Form
Nov
Volume
24
Issue
11
Start Page
1739
Other Pages
1747
Notes
LR: 20160715; CI: (c)2015; GR: K05 CA124911/CA/NCI NIH HHS/United States; GR: K05CA124911/CA/NCI NIH HHS/United States; GR: K24 DK100548/DK/NIDDK NIH HHS/United States; GR: P01 CA053996/CA/NCI NIH HHS/United States; GR: P01 CA091955/CA/NCI NIH HHS/United
Place of Publication
United States
ISSN/ISBN
1538-7755; 1055-9965
Accession Number
PMID: 26377193
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1158/1055-9965.EPI-15-0507 [doi]
Output Language
Unknown(0)
PMID
26377193
Abstract
BACKGROUND: Important risk factors for esophageal adenocarcinoma and its precursor, Barrett's esophagus, include gastroesophageal reflux disease, obesity, and cigarette smoking. Recently, genome-wide association studies have identified seven germline single-nucleotide polymorphisms (SNP) that are associated with risk of Barrett's esophagus and esophageal adenocarcinoma. Whether these genetic susceptibility loci modify previously identified exposure-disease associations is unclear. METHODS: We analyzed exposure and genotype data from the BEACON Consortium discovery phase GWAS, which included 1,516 esophageal adenocarcinoma case patients, 2,416 Barrett's esophagus case patients, and 2,187 control participants. We examined the seven newly identified susceptibility SNPs for interactions with body mass index, smoking status, and report of weekly heartburn or reflux. Logistic regression models were used to estimate ORs for these risk factors stratified by SNP genotype, separately for Barrett's esophagus and esophageal adenocarcinoma. RESULTS: The odds ratio for Barrett's esophagus associated with at least weekly heartburn or reflux varied significantly with the presence of at least one minor allele of rs2687201 (nominal P = 0.0005, FDR = 0.042). ORs (95% CIs) for weekly heartburn or reflux among participants with 0, 1, or 2 minor alleles of rs2687201 were 6.17 (4.91-7.56), 3.56 (2.85-4.44), and 3.97 (2.47-6.37), respectively. No statistically significant interactions were observed for smoking status and body mass index. CONCLUSION: Reflux symptoms are more strongly associated with Barrett's esophagus risk among persons homozygous for the major allele of rs2687201, which lies approximately 75 kb downstream of the transcription factor gene FOXP1. IMPACT: The novel gene-exposure interaction discovered in this study provides new insights into the etiology of esophageal adenocarcinoma.
Descriptors
Links
Book Title
Database
Publisher
American Association for Cancer Research
Data Source
Authors
Dai,J.Y., de Dieu Tapsoba,J., Buas,M.F., Onstad,L.E., Levine,D.M., Risch,H.A., Chow,W.H., Bernstein,L., Ye,W., Lagergren,J., Bird,N.C., Corley,D.A., Shaheen,N.J., Wu,A.H., Reid,B.J., Hardie,L.J., Whiteman,D.C., Vaughan,T.L.
Original/Translated Title
URL
Date of Electronic
20150916
PMCID
PMC4816532
Editors
The role of smokeless tobacco use in smoking persistence among male college students 2015 a Department of Social Sciences and Health Policy .; b Department of Biostatistical Sciences , and.; a Department of Social Sciences and Health Policy .; a Department of Social Sciences and Health Policy .; b Department of Biostatistical Sciences , and.;
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The American Journal of Drug and Alcohol Abuse
Periodical, Abbrev.
Am.J.Drug Alcohol Abuse
Pub Date Free Form
Volume
41
Issue
6
Start Page
541
Other Pages
546
Notes
LR: 20151029; GR: R01 CA141643/CA/NCI NIH HHS/United States; JID: 7502510; NIHMS730141; OID: NLM: NIHMS730141 [Available on 11/01/16]; OID: NLM: PMC4623432 [Available on 11/01/16]; OTO: NOTNLM; PMCR: 2016/11/01 00:00; 2015/09/16 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1097-9891; 0095-2990
Accession Number
PMID: 26375618
Language
eng
SubFile
Journal Article; Observational Study; IM
DOI
10.3109/00952990.2015.1078345 [doi]
Output Language
Unknown(0)
PMID
26375618
Abstract
BACKGROUND: Significant changes in the tobacco industry have led to heightened concern about co-use of cigarettes and smokeless tobacco (SLT) products. OBJECTIVES: The aim of this study was to assess whether male cigarette smokers who also used SLT products, in the first semester of their first year of college, were more or less likely than male cigarette smokers who did not use SLT products to still be smoking by the first semester of their senior year. METHODS: Using a longitudinal, observational study, we followed a cohort of undergraduate students from 11 four-year universities in North Carolina and Virginia through their college career. Mixed-effects logistic regression analysis was conducted to estimate the likelihood of being a current smoker fall of senior year for male students who used both cigarettes and SLT at baseline, compared to those who only smoked cigarettes, after adjustment for potential confounders (n = 274). RESULTS: At baseline, 67.2% of participants were smoking cigarettes only (no SLT use) and 32.8% were dual users (cigarettes and SLT). A total of 62% were still smoking at senior year. Dual users were 30% more likely to be current smokers senior year compared to cigarette only users, although this difference was not statistically significant. Having at least one friend who smoked cigarettes and heavier cigarette smoking at baseline were significantly related to senior year smoking. CONCLUSIONS: Our findings do not support the argument that SLT use may help male college smokers discontinue their smoking habit. In fact, it may contribute to smoking persistence.
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Book Title
Database
Publisher
Data Source
Authors
Wolfson,M., Suerken,C.K., Egan,K.L., Sutfin,E.L., Reboussin,B.A., Wagoner,K.G., Spangler,J.
Original/Translated Title
URL
Date of Electronic
20150916
PMCID
PMC4623432
Editors
Determinants of waterpipe use amongst adolescents in Northern Sweden: a survey of use pattern, risk perception, and environmental factors 2015 Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden. rathi.ramji@pubcare.uu.se.; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden. judy.arnetz@hc.msu.edu.; Department of Family Medicine,
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC research notes
Periodical, Abbrev.
BMC Res.Notes
Pub Date Free Form
15-Sep
Volume
8
Issue
Start Page
441
Other Pages
015-1413-4
Notes
LR: 20150918; JID: 101462768; OID: NLM: PMC4570251; 2014/10/07 [received]; 2015/09/07 [accepted]; 2015/09/15 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1756-0500; 1756-0500
Accession Number
PMID: 26374502
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/s13104-015-1413-4 [doi]
Output Language
Unknown(0)
PMID
26374502
Abstract
BACKGROUND: Determinants of waterpipe use in adolescents are believed to differ from those for other tobacco products, but there is a lack of studies of possible social, cultural, or psychological aspects of waterpipe use in this population. This study applied a socioecological model to explore waterpipe use, and its relationship to other tobacco use in Swedish adolescents. METHODS: A total of 106 adolescents who attended an urban high-school in northern Sweden responded to an anonymous questionnaire. Prevalence rates for waterpipe use were examined in relation to socio-demographics, peer pressure, sensation seeking behavior, harm perception, environmental factors, and depression. RESULTS: Thirty-three percent reported ever having smoked waterpipe (ever use), with 30% having done so during the last 30 days (current use). Among waterpipe ever users, 60% had ever smoked cigarettes in comparison to 32% of non-waterpipe smokers (95% confidence interval 1.4-7.9). The odds of having ever smoked waterpipe were three times higher among male high school seniors as well as students with lower grades. Waterpipe ever users had three times higher odds of having higher levels of sensation-seeking (95% confidence interval 1.2-9.5) and scored high on the depression scales (95% confidence interval 1.6-6.8) than non-users. The odds of waterpipe ever use were four times higher for those who perceived waterpipe products to have pleasant smell compared to cigarettes (95% confidence interval 1.7-9.8). Waterpipe ever users were twice as likely to have seen waterpipe use on television compared to non-users (95% confidence interval 1.1-5.7). The odds of having friends who smoked regularly was eight times higher for waterpipe ever users than non-users (95% confidence interval 2.1-31.2). CONCLUSION: The current study reports a high use of waterpipe in a select group of students in northern Sweden. The study adds the importance of looking at socioecological determinants of use, including peer pressure and exposure to media marketing, as well as mental health among users.
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Database
Publisher
Data Source
Authors
Ramji,R., Arnetz,J., Nilsson,M., Jamil,H., Norstrom,F., Maziak,W., Wiklund,Y., Arnetz,B.
Original/Translated Title
URL
Date of Electronic
20150915
PMCID
PMC4570251
Editors
Ebola Virus Disease--Sierra Leone and Guinea, August 2015 2015
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
11-Sep
Volume
64
Issue
35
Start Page
981
Other Pages
984
Notes
JID: 7802429; epublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 26355422
Language
eng
SubFile
Journal Article; IM
DOI
10.15585/mmwr.mm6435a6 [doi]
Output Language
Unknown(0)
PMID
26355422
Abstract
The Ebola virus disease (Ebola) outbreak in West Africa began in late 2013 in Guinea (1) and spread unchecked during early 2014. By mid-2014, it had become the first Ebola epidemic ever documented. Transmission was occurring in multiple districts of Guinea, Liberia, and Sierra Leone, and for the first time, in capital cities (2). On August 8, 2014, the World Health Organization (WHO) declared the outbreak to be a Public Health Emergency of International Concern (3). Ministries of Health, with assistance from multinational collaborators, have reduced Ebola transmission, and the number of cases is now declining. While Liberia has not reported a case since July 12, 2015, transmission has continued in Guinea and Sierra Leone, although the numbers of cases reported are at the lowest point in a year. In August 2015, Guinea and Sierra Leone reported 10 and four confirmed cases, respectively, compared with a peak of 526 (Guinea) and 1,997 (Sierra Leone) in November 2014. This report details the current situation in Guinea and Sierra Leone, outlines strategies to interrupt transmission, and highlights the need to maintain public health response capacity and vigilance for new cases at this critical time to end the outbreak.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Hersey,S., Martel,L.D., Jambai,A., Keita,S., Yoti,Z., Meyer,E., Seeman,S., Bennett,S., Ratto,J., Morgan,O., Akyeampong,M.A., Sainvil,S., Worrell,M.C., Fitter,D., Arnold,K.E.
Original/Translated Title
URL
Date of Electronic
20150911
PMCID
Editors
Elimination of Ebola Virus Transmission in Liberia - September 3, 2015 2015
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
11-Sep
Volume
64
Issue
35
Start Page
979
Other Pages
980
Notes
JID: 7802429; epublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 26355323
Language
eng
SubFile
Journal Article; IM
DOI
10.15585/mmwr.mm6435a5 [doi]
Output Language
Unknown(0)
PMID
26355323
Abstract
Following 42 days since the last Ebola virus disease (Ebola) patient was discharged from a Liberian Ebola treatment unit (ETU), September 3, 2015, marks the second time in a 4-month period that the World Health Organization (WHO) has declared Liberia free of Ebola virus transmission (1). The first confirmed Ebola cases in West Africa were identified in southeastern Guinea on March 23, 2014, and within 1 week, cases were identified and confirmed in Liberia (1). Since then, Liberia has reported 5,036 confirmed and probable Ebola cases and 4,808 Ebola-related deaths. The epidemic in Liberia peaked in late summer and early fall of 2014, when more than 200 confirmed and probable cases were reported each week .
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Database
Publisher
Data Source
Authors
Bawo,L., Fallah,M., Kateh,F., Nagbe,T., Clement,P., Gasasira,A., Mahmoud,N., Musa,E., Lo,T.Q., Pillai,S.K., Seeman,S., Sunshine,B.J., Weidle,P.J., Nyensweh,T., Liberia Ministry of Health, World Health Organization, CDC Ebola Response Teams
Original/Translated Title
URL
Date of Electronic
20150911
PMCID
Editors
Eliciting preferences for waterpipe tobacco smoking using a discrete choice experiment: implications for product regulation 2015 Department of Health Outcomes and Policy, Institute for Child Health Policy, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Epidemiology, Stempel College of Public Health and Social Work, Florida International Univers
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMJ open
Periodical, Abbrev.
BMJ Open
Pub Date Free Form
9-Sep
Volume
5
Issue
9
Start Page
e009497
Other Pages
2015-009497
Notes
LR: 20160413; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: R01 DA035160/DA/NIDA NIH HHS/United States; GR: R
Place of Publication
England
ISSN/ISBN
2044-6055; 2044-6055
Accession Number
PMID: 26353876
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1136/bmjopen-2015-009497 [doi]
Output Language
Unknown(0)
PMID
26353876
Abstract
OBJECTIVES: Waterpipe smoking is highly prevalent among university students, and has been increasing in popularity despite mounting evidence showing it is harmful to health. The aim of this study was to measure preferences for waterpipe smoking and determine which product characteristics are most important to smokers. SETTING: A large university in the Southeastern USA. PARTICIPANTS: Adult waterpipe smokers attending the university (N=367). DESIGN: Participants completed an Internet-based discrete choice experiment to reveal their preferences for, and trade-offs between, the attributes of hypothetical waterpipe smoking sessions. Participants were presented with waterpipe lounge menus, each with three fruit-flavoured options and one tobacco flavoured option, in addition to an opt out option. Nicotine content and price were provided for each choice. Participants were randomised to either receive menus with a text-only health-warning message or no message. OUTCOME MEASURES: Multinomial and nested logit models were used to estimate the impact on consumer choice of attributes and between-subject assignment of health warnings respectively. RESULTS: On average, participants preferred fruit-flavoured varieties to tobacco flavour. They were averse to options labelled with higher nicotine content. Females and non-smokers of cigarettes were more likely than their counterparts to prefer flavoured and nicotine-free varieties. Participants exposed to a health warning were more likely to opt out. CONCLUSIONS: Fruit-flavoured tobacco and lower nicotine content labels, two strategies widely used by the industry, increase the demand for waterpipe smoking among young adults. Waterpipe-specific regulation should limit the availability of flavoured waterpipe tobacco and require accurate labelling of constituents. Waterpipe-specific tobacco control regulation, along with research to inform policy, is required to curb this emerging public health threat.
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Database
Publisher
Data Source
Authors
Salloum,R.G., Maziak,W., Hammond,D., Nakkash,R., Islam,F., Cheng,X., Thrasher,J.F.
Original/Translated Title
URL
Date of Electronic
20150909
PMCID
PMC4567671
Editors