WTS database

Title	Pub Year	Author Sort ascending	SearchLink
Roll-your-own tobacco use among Canadian youth: is it a bigger problem than we think?	2012	School of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada, N2L 3G1. sleather@uwaterloo.ca	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC public health Periodical, Abbrev. BMC Public Health Pub Date Free Form 27-Jul Volume 12 Issue Start Page 557 Other Pages 2458-12-557 Notes LR: 20150224; JID: 100968562; OID: NLM: PMC3434020; 2012/03/26 [received]; 2012/07/03 [accepted]; 2012/07/27 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1471-2458; 1471-2458 Accession Number PMID: 22834563 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1186/1471-2458-12-557 [doi] Output Language Unknown(0) PMID 22834563 Abstract BACKGROUND: Despite the apparent decline in the popularity of roll-your-own (RYO) cigarettes over the past few decades, RYO tobacco products are widely available and used by a substantial number of adult smokers. Considering research has yet to examine the prevalence of RYO tobacco use among youth populations, this manuscript examines the prevalence of RYO tobacco use and factors associated with RYO use in a nationally representative sample of youth smokers from Canada. METHODS: This study used data collected from 3,630 current smokers in grades 9 to 12 as part of the 2008-09 Canadian Youth Smoking Survey (YSS). Descriptive analyses of the sample demographic characteristics, smoking status, cigarettes per day, weekly spending money, and frequency of marijuana use were examined by RYO tobacco ever use and RYO tobacco current use. Two logistic regression models were used to examine factors associated with RYO tobacco ever use and RYO tobacco current use. RESULTS: We identified that 51.2% of current smokers were RYO ever users and 24.2% were RYO current users. The prevalence of RYO current users was highest in Atlantic Canada (40.1%) and lowest in Quebec (12.3%). RYO current users were more likely to be male (OR 1.27), to be daily smokers (OR 1.75), to use marijuana once a month or more (OR 2.74), and to smoke 11 or more cigarettes per day (OR 6.52). RYO current users were less likely to be in grade 11 (OR 0.65) or grade 12 (OR 0.40) and less likely to have between $20 to $100 (OR 0.44) or more than $100 (OR 0.45) of disposable income. CONCLUSIONS: Developing a better understanding of RYO tobacco use among youth is important for advancing population-level tobacco control prevention strategies and cessation programs. We identified that RYO tobacco use is not a negligible problem among Canadian youth. Ongoing research is needed to continue monitoring the prevalence of RYO use among youth and the factors associated with its use, but to also monitor if this more affordable tobacco product is being targeted to price sensitive youth smokers. Descriptors Links Book Title Database Publisher Data Source Authors Leatherdale,S.T., Burkhalter,R. Original/Translated Title URL Date of Electronic 20120727 PMCID PMC3434020 Editors
Changes in tobacco use, susceptibility to future smoking, and quit attempts among Canadian youth over time: a comparison of off-reserve Aboriginal and non-Aboriginal youth	2013	School of Public Health and Health Systems, University of Waterloo, Waterloo, ON N2L 3G1, Canada. sleather@uwaterloo.ca	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of environmental research and public health Periodical, Abbrev. Int.J.Environ.Res.Public.Health. Pub Date Free Form 21-Feb Volume 10 Issue 2 Start Page 729 Other Pages 741 Notes LR: 20150219; JID: 101238455; OID: NLM: PMC3635174; 2012/12/05 [received]; 2013/01/17 [revised]; 2013/01/29 [accepted]; epublish Place of Publication Switzerland ISSN/ISBN 1660-4601; 1660-4601 Accession Number PMID: 23429753 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.3390/ijerph10020729 [doi] Output Language Unknown(0) PMID 23429753 Abstract The purpose of this study was to determine whether there is a growing inequity in tobacco use, susceptibility to future smoking, and quit attempts among Off-Reserve Aboriginal (ORA) youth in Canada relative to Non-Aboriginal youth. Current smoking, susceptibility to future smoking and quit attempts were examined among a nationally representative sample of ORA and Non-Aboriginal Canadian youth. Data are from cross-sectional surveys of 88,661 respondents in Grades 6 to 9 across the 2004, 2006 and 2008 survey waves of the Youth Smoking Survey (YSS). At each wave, ORA youth were more likely to be current smokers (overall OR = 3.91, 95% CI 3.47 to 4.41), to be susceptible to future smoking (overall OR = 1.37, 95% CI 1.27 to 1.48), and less likely to have ever made a quit attempt compared to Non-Aboriginal youth (overall OR = 0.74, 95% CI 0.57 to 0.96). Although susceptibility to future smoking declined for Non-Aboriginal youth, the prevalence of susceptibility remained stable among ORA youth. The percentage of ORA youth reporting making a quit attempt increased, however, current smoking rates among ORA youth did not decline. These findings suggest that the disparity in susceptibility to future tobacco use among ORA and Non-Aboriginal youth has increased over time. Despite increased rates of quit attempts, current smoking rates remain significantly higher among ORA youth. Tobacco control programs for Aboriginal youth should be a public health priority. Descriptors Links Book Title Database Publisher Data Source Authors Elton-Marshall,T., Leatherdale,S.T., Burkhalter,R., Brown,K.S. Original/Translated Title URL Date of Electronic 20130221 PMCID PMC3635174 Editors
The association between senior student tobacco use rate at school and alternative tobacco product use among junior students in Canadian secondary schools	2014	School of Public Health and Health Systems, University of Waterloo, 200 University Avenue, Waterloo, ON N2L 3G1, Canada.; School of Public Health and Health Systems, University of Waterloo, 200 University Avenue, Waterloo, ON N2L 3G1, Canada.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco induced diseases Periodical, Abbrev. Tob Induc Dis. Pub Date Free Form 1-May Volume 12 Issue 1 Start Page 8 Other Pages 9625-12-8. eCollection 2014 Notes LR: 20140512; JID: 101201591; OID: NLM: PMC4012246; OTO: NOTNLM; 2014 [ecollection]; 2014/04/02 [received]; 2014/04/25 [accepted]; 2014/05/01 [epublish]; epublish Place of Publication England ISSN/ISBN 2070-7266; 1617-9625 Accession Number PMID: 24808817 Language eng SubFile Journal Article DOI 10.1186/1617-9625-12-8 [doi] Output Language Unknown(0) PMID 24808817 Abstract BACKGROUND: The use of alternative tobacco products (ATPs) has grown in popularity among Canadian youth. This study examined the association between a school-level characteristic (the senior student tobacco use rate) and the current use of manufactured cigarettes, little cigars or cigarillos, cigars, roll-your-own cigarettes, smokeless tobacco (SLT), and a hookah among junior students. METHODS: This study used nationally representative Canadian data from 29,495 students in grades 9 to 12 as part of the 2010/2011 Youth Smoking Survey. For each ATP, we described rates of senior and junior tobacco use, calculated the variance attributed to school-level factors, and examined the association between the senior student (grades 11 and 12) tobacco use rate and the current use of each ATP among junior students (grades 9 and 10) while accounting for relevant student-level characteristics. SAS 9.3 was used for all analyses. RESULTS: Over half of schools sampled had senior students that reported using each ATP. School-level differences accounted for between 14.1% and 29.7% of the variability in ATP current use among junior students. Each one percent increase in the number of senior students at a school that currently use manufactured cigarettes, SLT, or a hookah was significantly independently associated with an increased likelihood that a junior student at that school currently used manufactured cigarettes (OR 1.04, 95% CI 1.01 to 1.06), SLT (OR 1.14, 95% CI 1.06 to 1.24), or a hookah (OR 1.09, 95% CI 1.03 to 1.14). CONCLUSIONS: Characteristics of the school environment a junior student attends appear to play an important role in ATP use, and tobacco control programs and policies should be designed to ensure that they include strategies to curb the use of all tobacco products. Additional evidence is needed for the impact of comprehensive school-based tobacco control approaches. Descriptors Links Book Title Database Publisher Data Source Authors Cole,A.G., Leatherdale,S.T. Original/Translated Title URL Date of Electronic 20140501 PMCID PMC4012246 Editors
Electronic cigarettes in Canada: prevalence of use and perceptions among youth and young adults	2014	School of Public Health & Health Systems University of Waterloo. cczoli@uwaterloo.ca.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Canadian journal of public health = Revue canadienne de sante publique Periodical, Abbrev. Can.J.Public Health Pub Date Free Form 3-Feb Volume 105 Issue 2 Start Page e97 Other Pages e102 Notes GR: Canadian Institutes of Health Research/Canada; JID: 0372714; OTO: NOTNLM; 2013/07/03 [received]; 2014/01/18 [accepted]; 2014/01/09 [revised]; epublish Place of Publication Canada ISSN/ISBN 1920-7476; 0008-4263 Accession Number PMID: 24886856 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI Output Language Unknown(0) PMID 24886856 Abstract OBJECTIVES: The goal of this study was to examine the prevalence and perceptions of electronic cigarette use among Canadian youth and young adults. METHODS: A sample of 1,188 youth and young adults age 16-30 years were recruited from an online panel of Canadians in 2012. After viewing an image of an e-cigarette, respondents answered questions regarding their use and perceptions of e-cigarettes. RESULTS: Close to half of respondents (43.4%) had seen e-cigarettes advertised or for sale. A total of 16.1% reported trying an e-cigarette (5.2% nonsmokers, 18.9% former smokers, and 34.5% current smokers), and 5.7% reported use in the past 30 days (0.8% non-smokers, 1.4% former smokers, and 15.0% current smokers). Compared to non-smokers, former smokers and current smokers were more likely to have tried e-cigarettes (OR=4.25 and OR=9.84, respectively), and current smokers were more likely to have tried e-cigarettes than former smokers (OR=2.32). Current smokers were also more likely to be current users of e-cigarettes than both former smokers (OR=15.15) and non-smokers (OR=4.43). Smokers were interested in trying e-cigarettes to help them quit smoking (80.4%), as a long-term replacement for cigarettes (77.8%), or to use in places where they cannot smoke (80.9%). CONCLUSIONS: Awareness of e-cigarettes among surveyed youth and young adults is quite high. Almost one fifth (16.1%) of participants reported trying e-cigarettes, with evidence of use among non-smokers. Descriptors Links Book Title Database Publisher Data Source Authors Czoli,C.D., Hammond,D., White,C.M. Original/Translated Title URL Date of Electronic 20140203 PMCID Editors
Updating the minimal important difference for six-minute walk distance in patients with chronic obstructive pulmonary disease	2010	School of Physiotherapy, La Trobe University, Melbourne, Australia. a.holland@alfred.org.au	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Archives of Physical Medicine and Rehabilitation Periodical, Abbrev. Arch.Phys.Med.Rehabil. Pub Date Free Form Feb Volume 91 Issue 2 Start Page 221 Other Pages 225 Notes LR: 20101118; CI: Copyright 2010; JID: 2985158R; 2009/08/05 [received]; 2009/10/12 [revised]; 2009/10/19 [accepted]; ppublish Place of Publication United States ISSN/ISBN 1532-821X; 0003-9993 Accession Number PMID: 20159125 Language eng SubFile Controlled Clinical Trial; Journal Article; AIM; IM DOI 10.1016/j.apmr.2009.10.017 [doi] Output Language Unknown(0) PMID 20159125 Abstract OBJECTIVE: To establish the minimal important difference (MID) for the six-minute walk distance (6MWD) in persons with chronic obstructive pulmonary disease (COPD). DESIGN: Analysis of data from an observational study using distribution- and anchor-based methods to determine the MID in 6MWD. SETTING: Outpatient pulmonary rehabilitation program at 2 teaching hospitals. PARTICIPANTS: Seventy-five patients with COPD (44 men) in a stable clinical state with mean age 70 years (SD 9 y), forced expiratory volume in one second 52% (SD 21%) predicted and baseline walking distance 359 meters (SD 104 m). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Participants completed the six-minute walk test before and after a 7-week pulmonary rehabilitation program. Participants and clinicians completed a global rating of change score while blinded to the change in 6MWD. RESULTS: The mean change in 6MWD in participants who reported themselves to be unchanged was 17.7 meters, compared with 60.2 meters in those who reported small change and 78.4 meters in those who reported substantial change (P=.004). Anchor-based methods identified an MID of 25 meters (95% confidence interval 20-61 m). There was excellent agreement with distribution-based methods (25.5-26.5m, kappa=.95). A change in 6MWD of 14% compared with baseline also represented a clinically important effect; this threshold was less sensitive than for absolute change (sensitivity .70 vs .85). CONCLUSIONS: The MID for 6MWD in COPD is 25 meters. Absolute change in 6MWD is a more sensitive indicator than percentage change from baseline. These data support the use of 6MWD as a patient-important outcome in research and clinical practice. Descriptors Aged, Aged, 80 and over, Cohort Studies, Exercise Test, Exercise Tolerance/physiology, Female, Forced Expiratory Volume, Humans, Male, Middle Aged, Outcome Assessment (Health Care), Predictive Value of Tests, Pulmonary Disease, Chronic Obstructive/physiopathology/rehabilitation, Self-Assessment, Walking/physiology Links Book Title Database Publisher American Congress of Rehabilitation Medicine. Published by Elsevier Inc Data Source Authors Holland,A. E., Hill,C. J., Rasekaba,T., Lee,A., Naughton,M. T., McDonald,C. F. Original/Translated Title URL Date of Electronic PMCID Editors
Six-minute walk distance in healthy Singaporean adults cannot be predicted using reference equations derived from Caucasian populations	2006	School of Physiotherapy, Curtin University of Technology, Perth, Western Australia, Australia.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Respirology (Carlton, Vic.) Periodical, Abbrev. Respirology Pub Date Free Form Mar Volume 11 Issue 2 Start Page 211 Other Pages 216 Notes LR: 20061115; JID: 9616368; CIN: Respirology. 2006 Sep;11(5):669-70; author reply 671-2. PMID: 16916347; ppublish Place of Publication Australia ISSN/ISBN 1323-7799; 1323-7799 Accession Number PMID: 16548908 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI RES [pii] Output Language Unknown(0) PMID 16548908 Abstract OBJECTIVES: The 6-min walk test (6MWT) is commonly used to assess the functional exercise capacity of individuals with cardiopulmonary disease. Recent studies have established regression equations to predict the 6-min walk distance (6MWD) in healthy Caucasian populations; however, regression equations have yet to be established for the Singaporean population. The aim of this study was to determine 6MWD in healthy Singaporeans and identify contributors to 6MWD in this population. We also compared measured 6MWD with predicted 6MWD from two regression equations derived in Caucasian subjects. METHODOLOGY: Thirty-five healthy subjects (32 Chinese, 16 men) aged between 45 and 85 years performed three walking tests using a standardized protocol. 6MWD was defined as the greatest distance achieved from the three tests. Heart rate (HR) was recorded each minute during the 6MWT. Other measurements included age, height, leg length, smoking history and self-reported physical activity. RESULTS: 6MWD was 560 +/- 105 m and was not significantly different between men and women (P = 0.19). 6MWD was related to age (r = -0.36, P = 0.03), height (r = 0.35, P = 0.04), leg length (r = 0.38, P = 0.02) and the maximum HR achieved on the 6MWT when expressed as a percentage of the predicted maximum HR (%predHRmax, r = 0.73, P < 0.001). Stepwise multiple regression analysis showed that age, height, weight and %predHRmax were independent contributors (P < 0.01) to 6MWD, explaining 78% of the variance. Predicted 6MWD using regression equations derived from Caucasian subjects exceeded measured 6MWD by more than 75 m (P < 0.001). CONCLUSIONS: This is the first study to report 6MWD for healthy Singaporeans aged 45-85 years. The regression equation developed in this study explained 78% of the variance in 6MWD. Published equations derived from Caucasian subjects overestimate 6MWD in Singaporean Chinese. Descriptors Aged, Aged, 80 and over, Asian Continental Ancestry Group, Body Composition, European Continental Ancestry Group, Exercise Test/standards, Female, Heart Rate, Humans, Male, Middle Aged, Reference Standards, Reference Values, Singapore, Spirometry, Walking/physiology Links Book Title Database Publisher Data Source Authors Poh,H., Eastwood,P. R., Cecins,N. M., Ho,K. T., Jenkins,S. C. Original/Translated Title URL Date of Electronic PMCID Editors
Should any workplace be exempt from smoke-free law: the Irish experience	2012	School of Physics, Dublin Institute of Technology, Dublin 8, Ireland.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of environmental and public health Periodical, Abbrev. J.Environ.Public.Health. Pub Date Free Form Volume 2012 Issue Start Page 545483 Other Pages Notes LR: 20151119; JID: 101516361; 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); 6M3C89ZY6R (Nicotine); 7U1EE4V452 (Carbon Monoxide); OID: NLM: PMC3368201; 2012/01/04 [received]; 2012/03/17 [revised]; 2012/03/27 [accepted]; 2012/05/24 [epublish]; ppubli Place of Publication United States ISSN/ISBN 1687-9813; 1687-9805 Accession Number PMID: 22693522 Language eng SubFile Journal Article; Multicenter Study; IM DOI 10.1155/2012/545483 [doi] Output Language Unknown(0) PMID 22693522 Abstract BACKGROUND: In 2004, the Irish Government introduced national legislation banning smoking in workplaces; with exemptions for "a place of residence". This paper summarises three Irish studies of exempted premises; prisons, psychiatric hospitals and nursing homes. METHODS: PM(2.5) and nicotine were measured in nursing homes and psychiatric hospitals, in addition to ultrafine particles in the hospitals. In the prisons, officers (n = 30) completed exhaled breath Carbon Monoxide (CO) measurements. Questionnaires determined officers' opinion on introducing smoking prohibitions in prisons. Nursing home smoking policies were examined and questionnaires completed by staff regarding workplace secondhand smoke (SHS) exposure. FINDINGS: Ultrafine particle concentrations in psychiatric hospitals averaged 130,000 cm(3), approximately 45% higher than Dublin pub (35.5 mug/m(3)) pre ban. PM(2.5) levels in psychiatric hospitals (39.5 mug/m(3)) were similar to Dublin pubs (35.5 mug/m(3)) pre ban. In nursing homes permitting smoking, similar PM(2.5) levels (33 mug/m(3)) were measured, with nicotine levels (0.57 mug/m(3)) four times higher than "non-smoking" nursing homes (0.13 mug/m(3)). In prisons, 44% of non-smoking officers exhibited exhaled breath CO criteria for light to heavy smokers. CONCLUSIONS: With SHS exposure levels in some exempted workplaces similar to Dublin pubs levels pre ban, policies ensuring full protection must be developed and implemented as a right for workers, inmates and patients. Descriptors Links Book Title Database Publisher Data Source Authors McCaffrey,M., Goodman,P., Gavigan,A., Kenny,C., Hogg,C., Byrne,L., McLaughlin,J., Young,K., Clancy,L. Original/Translated Title URL Date of Electronic 20120524 PMCID PMC3368201 Editors
Paliperidonium nitrate	2012	School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 1-Oct Volume 68 Issue Pt 10 Start Page o2932 Other Pages Notes JID: 101089178; OID: NLM: PMC3470306; 2012/07/09 [received]; 2012/09/07 [accepted]; 2012/09/15 [epublish]; ppublish Place of Publication United States ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 23125719 Language eng SubFile Journal Article DOI 10.1107/S160053681203841X [doi] Output Language Unknown(0) PMID 23125719 Abstract In the title mol-ecular salt (systematic name: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]eth-yl}-9-hy-droxy-2-methyl- 1,6,7,8,9,9a-hexa-hydro-pyrido[1,2-a]pyrimidin-4-one nitrate), C(23)H(29)FN(4)O(3) (+).NO(3) (-), the piperidine ring displays a chair conformation and its N atom is protonated; the N-H bond is in an axial orientation. The ring bearing the hy-droxy group exhibits a half-chair conformation. The hy-droxy group as well as the adjacent methyl-ene group are disordered over two sets of sites in a 0.823 (5):0.177 (5) ratio. In the crystal, O-Hcdots, three dots, centeredN, O-Hcdots, three dots, centeredO, N-Hcdots, three dots, centeredO and N-Hcdots, three dots, centeredN hydrogen bonds connect the components into a three-dimensional network. Descriptors Links Book Title Database Publisher Data Source Authors Ge,J., Luo,Y.H. Original/Translated Title URL Date of Electronic 20120915 PMCID PMC3470306 Editors
A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry	2014	School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.; School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.; School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.; School of Pharm	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Talanta Periodical, Abbrev. Talanta Pub Date Free Form Nov Volume 129 Issue Start Page 552 Other Pages 559 Notes CI: Copyright (c) 2014; JID: 2984816R; 0 (Anti-Inflammatory Agents, Non-Steroidal); 0 (Pyridines); 0 (Solvents); 0 (Water Pollutants, Chemical); 059QF0KO0R (Water); 7V31YC746X (Chloroform); NH9L3PP67S (pyridine); OTO: NOTNLM; 2014/05/02 [received]; 2014/0 Place of Publication Netherlands ISSN/ISBN 1873-3573; 0039-9140 Accession Number PMID: 25127632 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.talanta.2014.06.027 [doi] Output Language Unknown(0) PMID 25127632 Abstract Because of the high stability and potential toxic effects of non-steroidal anti-inflammatory drugs (NSAIDs), it is important to closely monitor their concentrations in the environment using a sensitive analytical method. In this study, a simple, rapid, efficient, and sensitive analytical method based on gas chromatography-mass spectrometry (GC-MS) was developed to determine the levels of seven common NSAIDs in various types of surface water. To simplify sample preparation, in situ derivatization using methyl chloroformate was combined with ultrasound-assisted emulsification microextraction. For selection and optimization of significant variables, experiments were statistically designed using Plackett-Burman design and central composite design. The resulting optimal conditions for derivatization and extraction were 100 muL of chloroform (extraction solvent), 10.0 mL of sample, and 240 muL of pyridine (catalyst as a base in derivatization). The optimized sample preparation coupled with optimized GC-MS analysis in selected ion monitoring mode provided good linearity from 0.010 to 5.0 ng mL(-1), and a limit of detection between 0.0050 and 0.010 ng mL(-1), good intra-day and inter-day precision (0.30-6.3% and 5.1-9.5%, respectively), and good accuracy (relative recovery; 91-117% at 0.20 ng mL(-1) and 77-105% at 2.5 ng mL(-1)). Compared with previously reported methods, the current method requires a small volume of sample and simple sample preparation steps for sensitive determination of NSAID levels using a conventional GC-MS system. The method was successfully applied to determine the levels of seven common NSAIDs in various types of surface water. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Lee,C.H., Shin,Y., Nam,M.W., Jeong,K.M., Lee,J. Original/Translated Title URL Date of Electronic 20140621 PMCID Editors
Biomonitoring method for the determination of polycyclic aromatic hydrocarbons in hair by online in-tube solid-phase microextraction coupled with high performance liquid chromatography and fluorescence detection	2015	School of Pharmacy, Shujitsu University, Nishigawara, Okayama 703-8516, Japan.; School of Pharmacy, Shujitsu University, Nishigawara, Okayama 703-8516, Japan.; School of Pharmacy, Shujitsu University, Nishigawara, Okayama 703-8516, Japan. Electronic addre	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.B, Analytical technologies in the biomedical and life sciences Periodical, Abbrev. J.Chromatogr.B.Analyt Technol.Biomed.Life.Sci. Pub Date Free Form 1-Sep Volume 1000 Issue Start Page 187 Other Pages 191 Notes CI: Copyright (c) 2015; JID: 101139554; 0 (Polycyclic Hydrocarbons, Aromatic); OTO: NOTNLM; 2015/04/29 [received]; 2015/07/06 [revised]; 2015/07/18 [accepted]; 2015/07/26 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-376X; 1570-0232 Accession Number PMID: 26245363 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.jchromb.2015.07.033 [doi] Output Language Unknown(0) PMID 26245363 Abstract Polycyclic aromatic hydrocarbons (PAHs) are formed from the incomplete combustion or pyrolysis of organic matter during industrial processing and various human activities, but human exposure to PAHs has not yet been elucidated in detail. To assess long-term exposure to PAHs, we developed a simple and sensitive method for measuring PAHs in hair by online in-tube solid-phase microextraction using a CP-Sil 19CB capillary column as an extraction device, followed by high-performance liquid chromatography using a Zorbax Eclipse PAH column and fluorescence detection. Seventeen PAHs could be analyzed simultaneously, with good linearity from 20 to 1000pg/mL each as determined using stable isotope-labeled PAH internal standards. The detection limits of PAHs were 0.5-20.4pg/mL. PAHs in human hair samples were extracted by ultrasonication in 50mM NaOH in methanol, and successfully analyzed without any interference peaks, with good recovery rates above 70% in spiked hair samples. Using this method, we evaluated the suitability of using hair PAHs as biomarkers for long-term exposure. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Yamamoto,Y., Ishizaki,A., Kataoka,H. Original/Translated Title URL Date of Electronic 20150726 PMCID Editors

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