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Youth tobacco surveillance--United States, 2000 2001
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.CDC surveillance summaries : Morbidity and mortality weekly report.CDC surveillance summaries / Centers for Disease Control
Periodical, Abbrev.
MMWR CDC Surveill.Summ.
Pub Date Free Form
2-Nov
Volume
50
Issue
4
Start Page
1
Other Pages
84
Notes
LR: 20120329; JID: 8407977; 0 (Tobacco Smoke Pollution); EIN: MMWR CDC Surveill Summ 2001 Nov 23;50(46):1036; ppublish
Place of Publication
United States
ISSN/ISBN
Accession Number
PMID: 11902401
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
11902401
Abstract
PROBLEM/CONDITION: Tobacco use is the single leading preventable cause of death in the United States, accounting for approximately 430,000 deaths each year. The prevalence of cigarette smoking nationwide among high school students increased during the 1990s, peaking during 1996-1997, then began a gradual decline. Approximately 80% of tobacco users initiate use before age 18 years. If the trend in early initiation of cigarette smoking continues, approximately 5 million children aged <18 years who are living today will die prematurely because they began to smoke cigarettes during adolescence. The economic costs associated with tobacco use ranges from $53 billion to $73 billion per year in medical expenses and $47 billion in lost productivity. Because of these health and economic consequences, CDC has recommended that states establish and maintain comprehensive tobacco-control programs to reduce tobacco use among youth. REPORTING PERIOD: January 2000 through December 2000. DESCRIPTION OF THE SYSTEM: To assist states in developing and maintaining their state-based comprehensive tobacco prevention and control programs, CDC developed the Youth Tobacco Surveillance and Evaluation System, which includes international, national, and state school-based surveys of middle school and high school students. Two components of this system are discussed in this report--the National Youth Tobacco Survey and the state Youth Tobacco Surveys. The national survey is representative of students in the 50 states and the District of Columbia; 35,828 students in 324 schools completed questionnaires in the spring of 2000. Twenty-nine state surveys were conducted in the spring and fall of 2000; state sample sizes ranged from 583 to 33,586 students. This report summarizes data from the 2000 national survey and state surveys. RESULTS AND INTERPRETATION: Findings from the National Youth Tobacco Survey indicate that current tobacco use ranges from 15.1% among middle school students to 34.5% among high school students. Cigarette smoking is the most prevalent form of tobacco use, followed by cigar smoking and smokeless tobacco use. Approximately one half of current cigarette smokers in middle school and high school report that they usually smoke Marlboro cigarettes. Black students are more likely to smoke Newport cigarettes than any other brand. More than one half of current cigarette smokers in middle school and high school report that they want to stop smoking. Nearly one fourth of middle school and high school students who have never smoked cigarettes are susceptible to initiating cigarette smoking in the next year. Exposure to secondhand smoke (e.g., environmental tobacco smoke) is substantially higher among both middle school and high school students. During the week before the survey, approximately 9 out of 10 current cigarette smokers and one half of never cigarette smokers were in the same room with someone who was smoking cigarettes; and 8 out of 10 current cigarette smokers and 3 out of 10 never cigarette smokers rode in a car with someone who was smoking cigarettes. Approximately 70% of middle school and 57% of high school students who currently smoke cigarettes live in a home where someone smokes cigarettes. Among never cigarette smokers, approximately 3 out of 10 live in a home where someone smokes cigarettes. Approximately 69% of middle school and 58% of high school students aged <18 years who currently smoke cigarettes were not asked to show proof of age when they bought or tried to buy cigarettes. Approximately 8 out of 10 middle school and high school students have seen antismoking commercials. Eight out of 10 middle school students report having seen actors using tobacco on television or in the movies, and approximately 11% of middle school and 16% of high school students who had never used tobacco would wear or use something with a tobacco company name or picture on it. This rate increases to nearly 60% for current tobacco users. PUBLIC
Descriptors
Adolescent, Advertising as Topic, Attitude, Child, Humans, Population Surveillance, Prevalence, Schools, Smoking/epidemiology/prevention & control/psychology, Smoking Cessation, Tobacco Smoke Pollution, United States/epidemiology
Links
Book Title
Database
Publisher
Data Source
Authors
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Hemoglobinuria producida por una fístula en la sutura perivalvular post reemplazo con prótesis valvular mitral 2001
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Periodical, Abbrev.
Acta med.peru
Pub Date Free Form
Volume
18
Issue
1
Start Page
31
Other Pages
34
Notes
ID: 506730
Place of Publication
ISSN/ISBN
Accession Number
Language
es
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
This is a case of 65 year old male with past medical history significant for coronary artery disease and severe mitral valve prolapse for which he underwent simultaneous coronary artery bypass graft using the saphenous vein, mitral valve replacement with a St. Jude prosthetic valve. There were no postoperative complications and after anticoagulation with warfarin the patient wa discharged home. Three months postoperatively the patient developed apparent "hematuria". Physical examination an extensive laboratory analysis of hemoglobinuria. Transthoracic echocardiogram revealed a perivalvular leakage with a normally functioning St. Jude mitral valve replacement. Clinical course was uneventful and the hemoglobinuria resolved spontaneously. This case illustrates the importances in determinig the etiology and pathophysiology of hemoglobinuria with transthoracic and transesophageal echocardiography. (AU)
Descriptors
Humans, Male, Aged, Hemoglobinuria, Heart Valve Prosthesis
Links
http://sisbib.unmsm.edu.pe/BVRevistas/acta_medica/2001_n1/pdf/a06.pdf
Book Title
Database
LILACS; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Agusti,Ré, Yuen,Alberto, Parodi,José
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Longitudinal evaluation of GCF MMP-3 and TIMP-1 levels as prognostic factors for progression of periodontitis 2001 University of the Pacific School of Dentistry, San Francisco, CA 94115, USA. talpagot@uop-edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of clinical periodontology
Periodical, Abbrev.
J.Clin.Periodontol.
Pub Date Free Form
Apr
Volume
28
Issue
4
Start Page
353
Other Pages
359
Notes
LR: 20151119; JID: 0425123; 0 (Biomarkers); 0 (Protease Inhibitors); 0 (Tissue Inhibitor of Metalloproteinase-1); EC 3.4.24.17 (Matrix Metalloproteinase 3); ppublish
Place of Publication
Denmark
ISSN/ISBN
0303-6979; 0303-6979
Accession Number
PMID: 11314892
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; D; IM
DOI
Output Language
Unknown(0)
PMID
11314892
Abstract
BACKGROUND: To determine whether matrix metalloproteinase-3 (MMP-3) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in gingival crevicular fluid (GCF) could serve as prognostic factors for the progression of periodontitis, we monitored GCF MMP-3 and TIMP-1 and periodontal status of selected sites in 40 medically healthy subjects over a 6-month period. METHOD: Clinical measurements including gingival index (GI), plaque index, bleeding on probing, suppuration, probing depth (PD), attachment loss (AL), and GCF samples were taken from 2 healthy sites (including sites with gingival recession, GI=0 PD or =1; PD > or =5 mm; AL > or =3 mm) of each patient at baseline, 3-month and 6-month visits by means of sterile paper strips. GCF levels of MMP-3 and TIMP-1 were determined by sandwich ELISA assays. RESULTS: The mean amounts of MMP-3 and TIMP-1 in diseased sites were significantly higher than in healthy sites (p<0.0001). Significantly higher GCF levels of MMP-3 and TIMP-1 were found at progressing sites than in nonprogressing periodontitis sites (0.001
or =2 mm loss of attachment during 6- month study period. GCF levels of MMP-3 were highly correlated with clinical measurements taken at baseline, 3-month and 6-month visits (p<0.001). TIMP-1 levels were only moderately correlated with probing depth and attachment level (p<0.01). Step-wise multiple regression analysis was performed to construct models for the prediction of probing depth and attachment loss increases. The most parsimonious regression models which had the best R2 values included the following variables and accounted for the indicated % of variability. The regression model for the prediction of probing depth increase included MMP-3, smoking pack-years, TIMP-1 and accounted for 53% of the variability. The best model for the prediction of attachment loss increase included MMP-3, smoking pack-years, age, TIMP-1 and explained 59% of the variability. CONCLUSION: These data indicate that sites with high GCF levels of MMP-3 and TIMP-1 are at significantly greater risk for progression of periodontitis.
Descriptors
Adult, Age Factors, Analysis of Variance, Biomarkers/analysis, Dental Plaque Index, Disease Progression, Female, Follow-Up Studies, Forecasting, Gingival Crevicular Fluid/enzymology, Gingival Hemorrhage/classification/enzymology, Gingival Recession/enzymology, Gingivitis/enzymology, Humans, Longitudinal Studies, Male, Matrix Metalloproteinase 3/analysis, Middle Aged, Periodontal Attachment Loss/classification/enzymology, Periodontal Index, Periodontal Pocket/classification/enzymology, Periodontitis/enzymology/physiopathology, Prognosis, Protease Inhibitors/analysis, Regression Analysis, Risk Factors, Smoking/physiopathology, Suppuration, Tissue Inhibitor of Metalloproteinase-1/analysis
Links
Book Title
Database
Publisher
Data Source
Authors
Alpagot,T., Bell,C., Lundergan,W., Chambers,D. W., Rudin,R.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Metabolites of a tobacco-specific lung carcinogen in nonsmoking women exposed to environmental tobacco smoke 2001 Division of Epidemiology, University of Minnesota, Minneapolis 55454, USA. anderson_k@epi.umn.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of the National Cancer Institute
Periodical, Abbrev.
J.Natl.Cancer Inst.
Pub Date Free Form
7-Mar
Volume
93
Issue
5
Start Page
378
Other Pages
381
Notes
LR: 20151119; GR: CA81301/CA/NCI NIH HHS/United States; JID: 7503089; 0 (4-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acid); 0 (Carcinogens); 0 (Glucuronates); 0 (Nitrosamines); 0 (Tobacco Smoke Pollution); 6M3C89ZY6R (Nicotine)
Place of Publication
United States
ISSN/ISBN
0027-8874; 0027-8874
Accession Number
PMID: 11238699
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; IM
DOI
Output Language
Unknown(0)
PMID
11238699
Abstract
BACKGROUND: Environmental tobacco smoke (ETS) is associated with lung cancer in nonsmokers. Most epidemiologic studies find a higher risk for lung cancer in nonsmoking women married to smokers than in those married to nonsmokers. We measured metabolites of a tobacco-specific lung carcinogen in urine from healthy, nonsmoking women exposed to ETS. METHODS: We recruited women and their partners through advertisements. Couples completed questionnaires on smoking history and demographics, and both partners provided 100 mL of urine; 23 women had male partners who smoked in the home (i.e., exposed women), and 22 women had male partners who did not smoke (i.e., unexposed women). Urine samples were analyzed for nicotine, for cotinine, for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronide (NNAL-Gluc), as well as for creatinine. NNAL and NNAL-Gluc are metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Unpaired Student's t tests were conducted on log-transformed values. All statistical tests are two-sided. RESULTS: Urinary levels of nicotine, cotinine, NNAL, and NNAL-Gluc were statistically significantly higher in exposed women than in unexposed women. Geometric means for these compounds in exposed versus unexposed women, respectively, were as follows: nicotine, 0.050 nmol/mg of creatinine (95% confidence interval [CI] = 0.033 to 0.076) versus 0.008 nmol/mg of creatinine (95% CI = 0.004 to 0.014); cotinine, 0.037 nmol/mg of creatinine (95% CI = 0.022 to 0.061) versus 0.007 nmol/mg of creatinine (95% CI = 0.004 to 0.011); NNAL, 0.013 pmol/mg of creatinine (95% CI = 0.007 to 0.024) versus 0.004 pmol/mg of creatinine (95% CI = 0.002 to 0.007); and NNAL-Gluc, 0.027 pmol/mg of creatinine (95% CI = 0.016 to 0.045) versus 0.004 pmol/mg of creatinine (95% CI = 0.003 to 0.006). CONCLUSIONS: Nonsmoking women exposed to ETS take up and metabolize the tobacco-specific lung carcinogen NNK, which could increase their risk of lung cancer. Within couples, the NNAL plus NNAL-Gluc level in exposed women compared with that of their smoking partners averaged 5.6%. Notably, epidemiologic studies have estimated the excess risk for lung cancer in nonsmoking women exposed to ETS as 1%-2% of that in smokers.
Descriptors
Adult, Aged, Carcinogens/adverse effects/metabolism, Cotinine/urine, Creatinine/urine, Female, Glucuronates/urine, Humans, Lung Neoplasms/etiology/metabolism/urine, Middle Aged, Nicotine/urine, Nitrosamines/urine, Risk, Risk Factors, Smoking/adverse effects, Surveys and Questionnaires, Tobacco Smoke Pollution/adverse effects
Links
Book Title
Database
Publisher
Data Source
Authors
Anderson,K. E., Carmella,S. G., Ye,M., Bliss,R. L., Le,C., Murphy,L., Hecht,S. S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The microbiology of South African traditional fermented milks 2001 ARC-Animal Nutrition and Animal Products Institute, Irene, South Africa. elbie@iapi.agric.za
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of food microbiology
Periodical, Abbrev.
Int.J.Food Microbiol.
Pub Date Free Form
15-Feb
Volume
63
Issue
3
Start Page
189
Other Pages
197
Notes
LR: 20061115; JID: 8412849; ppublish
Place of Publication
Netherlands
ISSN/ISBN
0168-1605; 0168-1605
Accession Number
PMID: 11246902
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
S0168160500004177 [pii]
Output Language
Unknown(0)
PMID
11246902
Abstract
A total of 15 samples of traditional fermented milk were collected from individual households in South Africa and Namibia. Lactic acid bacteria dominated the microflora of these samples, especially the genera Leuconostoc, Lactococcus and Lactobacillus. Other groups identified included pyogenic streptococci and enterococci. The dominant lactococci species was Lactococcus lactis subsp. lactis. Eighty-three percent of the leuconostoc isolates were identified as Leuconostoc mesenteroides subsp. dextranicum. Other species identified included Leuconostoc citreum, Leuconostoc lactis, Lactobacillus delbrueckii subsp. lactis and Lactobacillus plantarum.
Descriptors
Animals, Cattle, Colony Count, Microbial, Enterococcus/isolation & purification, Female, Fermentation, Food Microbiology, Hydrogen-Ion Concentration, Lactobacillus/classification/isolation & purification, Lactococcus/isolation & purification, Leuconostoc/isolation & purification, Milk/microbiology, Namibia, South Africa, Streptococcaceae/classification/isolation & purification, Streptococcus/isolation & purification
Links
Book Title
Database
Publisher
Data Source
Authors
Beukes,E. M., Bester,B. H., Mostert,J. F.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Negative effects of maternal smoking during the course of pregnancy 2001 Service de pediatrie-neonatologie, hopital Bon-Secours, 57038 Metz, France.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Archives de Pediatrie : Organe Officiel de la Societe Francaise de Pediatrie
Periodical, Abbrev.
Arch.Pediatr.
Pub Date Free Form
Aug
Volume
8
Issue
8
Start Page
875
Other Pages
881
Notes
LR: 20061115; JID: 9421356; 0 (Tobacco Smoke Pollution); ppublish
Place of Publication
France
ISSN/ISBN
0929-693X; 0929-693X
Accession Number
PMID: 11524920
Language
fre
SubFile
English Abstract; Journal Article; IM
DOI
S0929693X01006121 [pii]
Output Language
Unknown(0)
PMID
11524920
Abstract
Maternal smoking during pregnancy has many consequences, manifesting prior to, during and after pregnancy, mainly: fertility difficulties; obstetrical accidents such as extrauterine pregnancy, premature labour and early placenta detachment; intrauterine growth retardation; increased perinatal morbidity; increased susceptibility to respiratory diseases in infancy and childhood; increased rate of sudden infant death; and alteration of cognitive development and behavioral disorder in childhood. Postnatal smoke exposure increases the respiratory complications in infancy and childhood. Considering the severity of these deleterious effects, the development of a large preventive policy appears necessary.
Descriptors
Adult, Child, Child Welfare, Child, Preschool, Embryonic and Fetal Development, Female, Health Promotion, Humans, Infant, Infant Welfare, Infant, Newborn, Male, Maternal Health Services, Pregnancy, Pregnancy Complications/etiology, Prenatal Exposure Delayed Effects, Respiratory Tract Infections/etiology, Smoking/adverse effects, Tobacco Smoke Pollution/adverse effects
Links
Book Title
Database
Publisher
Data Source
Authors
Billaud,N., Lemarie,P.
Original/Translated Title
Effets deleteres du tabagisme maternel au cours de la grossesse
URL
Date of Electronic
PMCID
Editors
Water mains and distribution pipes in soil - External corrosion and protection methods 2001 Camitz, G., Swedish Corrosion Institute, SE-104 05 Stockholm, Sweden
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Water Science and Technology: Water Supply
Periodical, Abbrev.
Water Sc.Technol.Water Supply
Pub Date Free Form
2001/
Volume
1
Issue
3
Start Page
97
Other Pages
105
Notes
Place of Publication
ISSN/ISBN
1606-9749
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Extensive statistical investigations based on damage reports show that the corrosion damage frequency for buried water mains and distribution pipelines in Sweden increased during the 1970s and 1980s. For this reason, a number of statistical and technical investigations of the corrosion and counter-measures were carried out. The paper reports on the corrosion damage statistics for water pipelines and the costs of the corrosion damage. Further, ways of actively working to reduce the corrosion damage frequency are described. These measures include the introduction of cast iron pipes with high quality coatings and the application of cathodic protection on different types of existing pipelines, and, further, the systematic replacement of pipeline sections, which show a high corrosion damage frequency.
Descriptors
drinking water, iron, conference paper, corrosion, pipeline, soil, statistics, Sweden, water supply
Links
Book Title
Database
Embase
Publisher
Data Source
Embase
Authors
Camitz,G.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
ER-YAG laser pretreatment effect on in vitro secondary caries formation around composite restorations 2001 Departamento de Materiales Dentales, Escuela de Odontologia, Universidad de Granada, Spain.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Dentistry
Periodical, Abbrev.
Am.J.Dent.
Pub Date Free Form
Feb
Volume
14
Issue
1
Start Page
46
Other Pages
49
Notes
LR: 20151119; JID: 8806701; 0 (Acetates); 0 (Aluminum Silicates); 0 (Composite Resins); 0 (Phosphoric Acids); 0 (Resin Cements); 0 (Z100 composite resin); 58784XQC3Y (Yttrium); 7631-86-9 (Silicon Dioxide); 77B218D3YE (Erbium); 90881-69-9 (Scotchbond); C6V
Place of Publication
United States
ISSN/ISBN
0894-8275; 0894-8275
Accession Number
PMID: 11806480
Language
eng
SubFile
Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; D
DOI
Output Language
Unknown(0)
PMID
11806480
Abstract
PURPOSE: This in vitro study determined if Er-YAG laser used in instead of acid-etching influenced artificial secondary caries formation in enamel and root surfaces. MATERIALS AND METHODS: Class V cavities were prepared in buccal and lingual surfaces of 10 extracted caries-free molars, with cervical margins in the root surface and occlusal margins in enamel. The specimens were randomly assigned to 2 groups: Group 1: Enamel and dentin etched with 35% phosphoric acid gel (Scotchbond 15s, rinse 10s; n=5 teeth with 2 cavities per specimen, 10 occlusal and 10 root surface margins at caries risk). Group 2: Enamel and dentin surfaces conditioned using a pulsed Er-YAG laser (KAVO) with 2.94 microm wavelength, 250 micros pulse duration, 300 mJ for enamel and 250 mJ for root surface pulse energy, 2 Hz repetition rate, and water cooling (n=5 teeth with 2 cavities per specimen, 10 occlusal and 10 root surface margins at caries risk). The cavity preparations were restored with a wet-bonding technique (Scotchbond 1 adhesive system) and a hybrid resin, light-cured composite (Z100, A3 shade), according to the manufacturer's instructions. Acid-resistant varnish was applied leaving the restoration and a 1 mm rim of adjacent surface enamel and root surface exposed. The specimens were thermocycled (5-50 degrees C, 500 cycles, dwell time 30s). Following artificial caries formation (2.2 mM calcium, 2.2 mM phosphate, 50 mM acetic acid, 5.0 mg/L fluoride, pH 4.25, 10 days), longitudinal sections (3/tooth, 30 occlusal and cervical caries risk sites per group) were taken for polarized light microscopic examination (water imbibition). Primary surface lesion depth and wall lesion frequency was determined and compared between groups (Student's t-test). RESULTS: Er-YAG laser irradiation resulted in a 56% reduction in primary enamel surface lesion depth (116 microm mean depth) when compared with the acid-etched group (263 microm mean depth), and a 39% decrease in root surface lesion depth (194 microm mean depth) compared with that (316 microm mean depth) for acid-etching pretreatment (P0.05) between treatment groups.
Descriptors
Acetates, Acid Etching, Dental, Aluminum Silicates, Composite Resins/chemistry, Dental Caries/pathology/prevention & control, Dental Caries Susceptibility, Dental Cavity Preparation/classification, Dental Enamel/radiation effects/ultrastructure, Dental Restoration, Permanent, Dentin/radiation effects/ultrastructure, Erbium, Humans, Hydrogen-Ion Concentration, Low-Level Light Therapy, Microscopy, Polarization, Molar, Phosphoric Acids/administration & dosage, Recurrence, Resin Cements/chemistry, Silicon Dioxide, Statistics as Topic, Thermodynamics, Tooth Demineralization/pathology/prevention & control, Tooth Root/radiation effects/ultrastructure, Yttrium, Zirconium
Links
Book Title
Database
Publisher
Data Source
Authors
Ceballos,L., Toledano,M., Osorio,R., Garcia-Godoy,F., Flaitz,C., Hicks,J.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Poverty and malaria: a study in a Thai-Myanmar border area. 2001 Panvisavas, S., Faculty of Social Sciences and Humanities, Mahidol University, Salaya, Nakhon Pathom, Thailand.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Southeast Asian journal of tropical medicine and public health
Periodical, Abbrev.
Southeast Asian J.Trop.Med.Public Health
Pub Date Free Form
/
Volume
32
Issue
3
Start Page
608
Other Pages
614
Notes
Place of Publication
ISSN/ISBN
0125-1562
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
An eight-month qualitative study was conducted in 1999 in four villages of Bong Tee subdistrict, Kanchanaburi Province located along the Thai-Myanmar border area using in-depth interviews of key informants and malaria survey as research methodologies. Malaria was a serious problem in 39.6% of the families surveyed in June 1999. The four villages located in a valley covered with forests and small streams which were ideal for malaria epidemic. The structure of the villages has been changed from stable communities to disrupted ones divided along ethnic and class lines. There were 5 ethnic groups dominated by ethnic Karen. Villagers were poor and thus deprived of anti-malaria resources which allow them to remain exposed to malaria.
Descriptors
article, economics, ethnology, health care organization, human, malaria, Myanmar, poverty, Thailand
Links
Book Title
Database
MEDLINE
Publisher
Data Source
Embase
Authors
Panvisavas,S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms 2001 Department of Microbiology, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, Texas 78245, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
Sep
Volume
45
Issue
9
Start Page
2475
Other Pages
2479
Notes
LR: 20140613; JID: 0315061; 0 (Antifungal Agents); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); OID: NLM: PMC90680; ppublish
Place of Publication
United States
ISSN/ISBN
0066-4804; 0066-4804
Accession Number
PMID: 11502517
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
Output Language
Unknown(0)
PMID
11502517
Abstract
Candida albicans is implicated in many biomaterial-related infections. Typically, these infections are associated with biofilm formation. Cells in biofilms display phenotypic traits that are dramatically different from those of their free-floating planktonic counterparts and are notoriously resistant to antimicrobial agents. Consequently, biofilm-related infections are inherently difficult to treat and to fully eradicate with normal treatment regimens. Here, we report a rapid and highly reproducible microtiter-based colorimetric assay for the susceptibility testing of fungal biofilms, based on the measurement of metabolic activities of the sessile cells by using a formazan salt reduction assay. The assay was used for in vitro antifungal susceptibility testing of several C. albicans strains grown as biofilms against amphotericin B and fluconazole and the increased resistance of C. albicans biofilms against these antifungal agents was demonstrated. Because of its simplicity, compatibility with a widely available 96-well microplate platform, high throughput, and automation potential, we believe this assay represents a promising tool for the standardization of in vitro antifungal susceptibility testing of fungal biofilms.
Descriptors
Amphotericin B/pharmacology, Antifungal Agents/pharmacology, Biofilms/drug effects, Candida albicans/drug effects, Cell Count, Colorimetry, Fluconazole/pharmacology, Humans, Microbial Sensitivity Tests/standards, Reproducibility of Results
Links
Book Title
Database
Publisher
Data Source
Authors
Ramage,G., Vande Walle,K., Wickes,B. L., Lopez-Ribot,J. L.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC90680
Editors