WTS database

Title Sort ascending	Pub Year	Author	SearchLink
A curcumin-loaded liquid crystal precursor mucoadhesive system for the treatment of vaginal candidiasis	2015	School of Pharmaceutical Sciences, UNESP - Sao Paulo State University, Campus Araraquara, Department of Drugs and Medicines, Araraquara, Sao Paulo, Brazil.; School of Pharmaceutical Sciences, UNESP - Sao Paulo State University, Campus Araraquara, Departme	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of nanomedicine Periodical, Abbrev. Int.J.Nanomedicine Pub Date Free Form 30-Jul Volume 10 Issue Start Page 4815 Other Pages 4824 Notes LR: 20150812; JID: 101263847; 0 (Drug Carriers); IT942ZTH98 (Curcumin); OID: NLM: PMC4525803; OTO: NOTNLM; 2015 [ecollection]; 2015/07/30 [epublish]; epublish Place of Publication New Zealand ISSN/ISBN 1178-2013; 1176-9114 Accession Number PMID: 26257519 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.2147/IJN.S82385 [doi] Output Language Unknown(0) PMID 26257519 Abstract Women often develop vaginal infections that are caused primarily by organisms of the genus Candida. The current treatments of vaginal candidiasis usually involve azole-based antifungals, though fungal resistance to these compounds has become prevalent. Therefore, much attention has been given to molecules with antifungal properties from natural sources, such as curcumin (CUR). However, CUR has poor solubility in aqueous solvents and poor oral bioavailability. This study attempted to overcome this problem by developing, characterizing, and evaluating the in vitro antifungal action of a CUR-loaded liquid crystal precursor mucoadhesive system (LCPM) for vaginal administration. A low-viscosity LCPM (F) consisting of 40% wt/wt polyoxpropylene-(5)-polyoxyethylene-(20)-cetyl alcohol, 50% wt/wt oleic acid, and 10% wt/wt chitosan dispersion at 0.5% with the addition of 16% poloxamer 407 was developed to take advantage of the lyotropic phase behavior of this formulation. Notably, F could transform into liquid crystal systems when diluted with artificial vaginal mucus at ratios of 1:3 and 1:1 (wt/wt), resulting in the formation of F30 and F100, respectively. Polarized light microscopy and rheological studies revealed that F behaved like an isotropic formulation, whereas F30 and F100 behaved like an anisotropic liquid crystalline system (LCS). Moreover, F30 and F100 presented higher mucoadhesion to porcine vaginal mucosa than F. The analysis of the in vitro activity against Candida albicans revealed that CUR-loaded F was more potent against standard and clinical strains compared with a CUR solution. Therefore, the vaginal administration of CUR-loaded LCPMs represents a promising platform for the treatment of vaginal candidiasis. Descriptors Links Book Title Database Publisher Data Source Authors Salmazi,R., Calixto,G., Bernegossi,J., Ramos,M.A., Bauab,T.M., Chorilli,M. Original/Translated Title URL Date of Electronic 20150730 PMCID PMC4525803 Editors
A cross-sectional study on the relationship between behavioral variables and economic status in periodontal disease among elderly individuals	2012	Department of Periodontics, KGF Dental College and Hospital, Bengaluru, Karnataka, India. drprasannar@gmail.com	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The journal of contemporary dental practice Periodical, Abbrev. J.Contemp.Dent.Pract. Pub Date Free Form 1-Sep Volume 13 Issue 5 Start Page 699 Other Pages 702 Notes JID: 101090552; epublish Place of Publication India ISSN/ISBN 1526-3711; 1526-3711 Accession Number PMID: 23250178 Language eng SubFile Comparative Study; Journal Article; D; IM DOI 1526-3711-949 [pii] Output Language Unknown(0) PMID 23250178 Abstract OBJECTIVES: The objectives of this study were to examine the relationship between behavioral variables, such as smoking and level of income on the periodontal disease among older South Indian adults. MATERIALS AND METHODS: Data pertaining to participants aged 55 years and above from the Outpatient Department of MR Ambedkar Dental College and Hospital were used. A total of 209 elderly subjects were selected by convenient sampling and a complete evaluation of their periodontal status was carried out. RESULTS: Our study showed that patients belonging to the lower income group and smokers had more severe disease compared to other groups. They were found to have higher plaque scores, higher calculus scores, deeper pockets and attachment loss compared to the subjects of the other groups. CONCLUSION: Variables, such as smoking, gender and low income are associated with the severity of periodontal disease in older adults. Descriptors Links Book Title Database Publisher Data Source Authors Prasanna,H.R., Chandan,D.N., Kripal,K., Hari,K.R., Adarsh,C.M., Reddy,T.P. Original/Translated Title URL Date of Electronic 20120901 PMCID Editors
A cross-sectional study on levels of second-hand smoke in restaurants and bars in five cities in China	2010	Chinese National Center for Disease Control and Prevention, Beijing, China. ruiling_liu@berkeley.edu	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Oct Volume 19 Suppl 2 Issue Start Page i24 Other Pages 9 Notes LR: 20141204; GR: P50 CA111236/CA/NCI NIH HHS/United States; GR: R01 CA125116/CA/NCI NIH HHS/United States; JID: 9209612; 0 (Tobacco Smoke Pollution); OID: NLM: PMC2976000; 2009/12/11 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 20008154 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1136/tc.2009.029959 [doi] Output Language Unknown(0) PMID 20008154 Abstract OBJECTIVES: To assess indoor second-hand smoke (SHS) exposure in restaurants and bars via PM(2.5) (fine particles 2.5 mum in diameter and smaller) level measurements in five cities in China. METHODS: The study was conducted from July to September in 2007 in Beijing, Xi'an, Wuhan, Kunming and Guiyang. Portable aerosol monitors were used to measure PM(2.5) concentrations in 404 restaurants and bars. The occupant density and the active smoker density were calculated for each venue sampled. RESULTS: Among the 404 surveyed venues, 23 had complete smoking bans, 9 had partial smoking bans and 313 (77.5%) were observed to have allowed smoking during sampling. The geometric mean of indoor PM(2.5) levels in venues with smoking observed was 208 mug/m(3) and 99 mug/m(3) in venues without observed smoking. When outdoor PM(2.5) levels were adjusted, indoor PM(2.5) levels in venues with smoking observed were consistently significantly higher than in venues without smoking observed (F=80.49, p<0.001). Indoor PM(2.5) levels were positively correlated with outdoor PM(2.5) levels (partial rho=0.37 p<0.001) and active smoker density (partial rho=0.34, p<0.001). CONCLUSIONS: Consistent with findings in other countries, PM(2.5) levels in smoking places are significantly higher than those in smoke-free places and are strongly related to the number and density of active smokers. These findings document the high levels of SHS in hospitality venues in China and point to the urgent need for comprehensive smoke-free laws in China to protect the public from SHS hazards, as called for in Article 8 of the Framework Convention on Tobacco Control, which was ratified by China in 2005. Descriptors Air Pollution, Indoor/legislation & jurisprudence/statistics & numerical data, China, Cross-Sectional Studies, Data Collection, Environmental Exposure/legislation & jurisprudence/statistics & numerical data, Environmental Monitoring/methods, Humans, Public Health, Restaurants/legislation & jurisprudence/statistics & numerical data, Smoking/legislation & jurisprudence, Tobacco Smoke Pollution/analysis/legislation & jurisprudence/statistics & numerical data Links Book Title Database Publisher Data Source Authors Liu,R. L., Yang,Y., Travers,M. J., Fong,G. T., O'Connor,R. J., Hyland,A., Li,L., Nan,Y., Feng,G. Z., Li,Q., Jiang,Y. Original/Translated Title URL Date of Electronic 20091211 PMCID PMC2976000 Editors
A cross-sectional study of determinants of indoor environmental exposures in households with and without chronic exposure to biomass fuel smoke	2014	Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1800 Orleans Ave, Suite 9121, Baltimore, MD, USA. wcheckl1@jhmi.edu.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Environmental health : a global access science source Periodical, Abbrev. Environ.Health Pub Date Free Form 24-Mar Volume 13 Issue 1 Start Page 21 Other Pages 069X-13-21 Notes LR: 20150514; GR: 5R25TW009340/TW/FIC NIH HHS/United States; GR: P30ES003819/ES/NIEHS NIH HHS/United States; GR: R00HL096955/HL/NHLBI NIH HHS/United States; JID: 101147645; 0 (Particulate Matter); 0 (Smoke); 7U1EE4V452 (Carbon Monoxide); OID: NLM: PMC3978 Place of Publication England ISSN/ISBN 1476-069X; 1476-069X Accession Number PMID: 24655424 Language eng SubFile Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; IM DOI 10.1186/1476-069X-13-21 [doi] Output Language Unknown(0) PMID 24655424 Abstract BACKGROUND: Burning biomass fuels indoors for cooking is associated with high concentrations of particulate matter (PM) and carbon monoxide (CO). More efficient biomass-burning stoves and chimneys for ventilation have been proposed as solutions to reduce indoor pollution. We sought to quantify indoor PM and CO exposures in urban and rural households and determine factors associated with higher exposures. A secondary objective was to identify chronic vs. acute changes in cardiopulmonary biomarkers associated with exposure to biomass smoke. METHODS: We conducted a census survey followed by a cross-sectional study of indoor environmental exposures and cardiopulmonary biomarkers in the main household cook in Puno, Peru. We measured 24-hour indoor PM and CO concentrations in 86 households. We also measured PM2.5 and PM10 concentrations gravimetrically for 24 hours in urban households and during cook times in rural households, and generated a calibration equation using PM2.5 measurements. RESULTS: In a census of 4903 households, 93% vs. 16% of rural vs. urban households used an open-fire stove; 22% of rural households had a homemade chimney; and Descriptors Links Book Title Database Publisher Data Source Authors Pollard,S.L., Williams,D.L., Breysse,P.N., Baron,P.A., Grajeda,L.M., Gilman,R.H., Miranda,J.J., Checkley,W., CRONICAS Cohort Study Group Original/Translated Title URL Date of Electronic 20140324 PMCID PMC3978088 Editors
A cross-sectional analysis of the prevalence of Barrett esophagus in otolaryngology patients with laryngeal symptoms	2013	*Department of Cardiothoracic Surgery, Division of Thoracic and Foregut Surgery, University of Pittsburgh section signDepartment of Surgery, Western Pennsylvania Hospital, West Penn Allegheny Health System, Pittsburgh, PA Departments of daggerOtolaryngolo	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of clinical gastroenterology Periodical, Abbrev. J.Clin.Gastroenterol. Pub Date Free Form Oct Volume 47 Issue 9 Start Page 762 Other Pages 768 Notes LR: 20150426; GR: K07 CA151613/CA/NCI NIH HHS/United States; GR: K23 DK066165/DK/NIDDK NIH HHS/United States; GR: K23 DK066165-01/DK/NIDDK NIH HHS/United States; GR: R21 DK081161-01/DK/NIDDK NIH HHS/United States; GR: U01 DK57132/DK/NIDDK NIH HHS/United S Place of Publication United States ISSN/ISBN 1539-2031; 0192-0790 Accession Number PMID: 23751847 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1097/MCG.0b013e318293d522 [doi] Output Language Unknown(0) PMID 23751847 Abstract BACKGROUND: Populations at risk for esophageal adenocarcinoma remain poorly defined. Laryngeal symptoms can be secondary to laryngopharyngeal reflux (LPR) and can occur without associated gastroesophageal reflux symptoms such as heartburn and regurgitation. GOAL: We sought to determine the prevalence of Barrett esophagus (BE) in otolaryngology patients with laryngeal symptoms+/-typical gastroesophageal reflux disease (GERD) symptoms. STUDY: We performed a cross-sectional study of otolaryngology clinic patients who reported laryngeal symptoms. Symptoms, medications, and exposure histories were obtained. Unsedated transnasal endoscopy was performed. Suspected BE was biopsied and confirmed histologically. Risk factors and prevalence of BE were assessed. RESULTS: Two hundred ninety-five patients were enrolled [73% male, median age 60 y (interquartile range 51 to 68 y)]. The overall prevalence of BE was 11.8% (n=33). Antisecretory medication use was present in 56% (n=156) of patients at enrollment. Compared with patients without BE, patients with BE were more likely to be male (P=0.01) and to report occupational lung injury (P=0.001). Duration, but not severity of laryngeal symptoms, significantly increased the odds of BE (odds ratio, 5.64; 95% confidence interval, 1.28-24.83; for a duration of symptoms >5 y). Of patients with BE, 58% (n=19) had coexisting LPR and GERD symptoms and 30% (n=10) had only LPR symptoms. Presence and size of hiatal hernia and length of columnar-lined esophagus were significant risk factors for BE. CONCLUSIONS: Long-standing laryngeal symptoms are associated with the presence of BE in otolaryngology patients. Patients with chronic laryngeal symptoms and no identifiable ear, nose, or throat etiology for those symptoms may benefit from endoscopic screening regardless of whether typical GERD symptoms are present. Descriptors Links Book Title Database Publisher Data Source Authors Nason,K.S., Murphy,T., Schindler,J., Schipper,P.H., Hoppo,T., Diggs,B.S., Sauer,D.A., Shaheen,N.J., Morris,C.D., Jobe,B.A., Barrett's Esophagus Risk Consortium (BERC) Original/Translated Title URL Date of Electronic PMCID PMC4169870 Editors
A critique of the WHO TobReg's "Advisory Note" report entitled: "Waterpipe tobacco smoking: Health effects, research needs and recommended actions by regulators"	2006	Chaouachi, K., Department of Tobacco Control, 92100 Boulogne Billancourt, France	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of Negative Results in BioMedicine Periodical, Abbrev. J.Negat.Results Biomed. Pub Date Free Form 2006/11 Volume 5 Issue Start Page Other Pages Notes Place of Publication ISSN/ISBN 1477-5751; 1477-5751 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Background and aim: The World Health Organisation Study Group on Tobacco Product Regulation (TobReg) has issued in 2005 an "Advisory Note" entitled: "Waterpipe Tobacco Smoking: Health Effects, Research Needs and Recommended Actions by Regulators". "Waterpipe" smoking is now considered a global public health threat and the corresponding artefact is actually known in the world under three main terms: hookah, narghile and shisha. This important report, the first ever prepared by WHO on the subject, poses two major problems. On one hand, its bibliographical references dismiss world chief relevant studies. On the other, it contains a certain number of errors of many orders: biomedical, sociological, anthropological and historical. The purpose of the present study is to highlight, one by one, where these weaknesses and errors lie and show how this official report can be considerably improved. Results: We realise that widely advertised early anthropological studies were not taken into consideration whereas they shed a substantial light on this peculiar form of smoking and help understanding its high complexity. As for concrete errors to be found in this report, they deal with the chemistry of smoke, health-related effects, smoking patterns, description and history of the artefact and its use, gender and underage use aspects, prevention and research needs in this field. Conclusion: The scientific credibility of an international expert report may be at stake if its recommendations do not rely on sound objective research findings and a comprehensive review of the existing literature. The critical comments in this study will certainly help improve the present WHO report. Â© 2006 Chaouachi; licensee BioMed Central Ltd. Descriptors nicotine, tar, analytical error, health hazard, human, infection, medical research, needs assessment, review, smoking, tobacco, world health organization Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Chaouachi,K. Original/Translated Title URL http://www.jnrbm.com/content/pdf/1477-5751-5-17.pdf Date of Electronic PMCID Editors
A critique of recent hypotheses on oral (and lung) cancer induced by water pipe (hookah, shisha, narghile) tobacco smoking	2010		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Med Hypotheses Periodical, Abbrev. Med.Hypotheses Pub Date Free Form Volume 74 Issue 5 Start Page 843 Other Pages 6 Notes ID: 20036075 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract The medical hypothesis that the mainstream smoke (the one inhaled by the user) from "water pipes" (mainly: shisha, hookah, narghile) causes oral cancer is certainly acceptable. However, most of the recent reviews on this issue, including an attempt to develop an hypothesis for hookah carcinogenesis, have not cited key references of the world available literature which, so far, generally do not support such an hypothesis. Besides, the proposal is biased since it is apparently an adaptation of the cigarette model whereas cigarette and hookah smokes are, chemically to start with, completely different. Furthermore, all water pipes, despite their striking varieties and the consequences on the chemical processes, are, according to the same cancer-hypothesis, considered as one. The reason is the use, in the cited mainstream literature, of a nominalism ("waterpipe", often in one word) which does not allow any distinction between devices. This critical article suggests to take into account all the peculiar characteristics into consideration in order to come up with another (or several other) carcinogenesis model(s). "Firmly believing] that water pipe smoking can provoke lung cancer as well as oral cancer", based on what may be seen as a rather reductionist view of the issue, is not enough. Descriptors Lung Neoplasms/etiology, Models, Biological, Mouth Neoplasms/etiology, Smoking/adverse effects, Humans, Review Literature as Topic Links http://dx.doi.org/10.1016/j.mehy.2009.11.036 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Chaouachi,Kamal, Sajid,Khan Mohammad Original/Translated Title URL Date of Electronic PMCID Editors
A comprehensive examination of hookah smoking in college students: use patterns and contexts, social norms and attitudes, harm perception, psychological correlates and co-occurring substance use	2013	Center for Health Care Evaluation, Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, USA. aheinz@stanford.edu	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addictive Behaviors Periodical, Abbrev. Addict.Behav. Pub Date Free Form Nov Volume 38 Issue 11 Start Page 2751 Other Pages 2760 Notes LR: 20151119; CI: (c) 2013; JID: 7603486; OTO: NOTNLM; 2013/03/29 [received]; 2013/06/21 [revised]; 2013/07/15 [accepted]; 2013/07/23 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1873-6327; 0306-4603 Accession Number PMID: 23934006 Language eng SubFile Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; IM DOI 10.1016/j.addbeh.2013.07.009 [doi] Output Language Unknown(0) PMID 23934006 Abstract The practice of waterpipe smoking (hookah) has rapidly increased in popularity among young adults yet burgeoning research suggests that its use is associated with nicotine dependence and other negative smoking-related health consequences. Moreover, descriptive studies indicate that consumers may hold the belief that hookah smoking is safer than smoking cigarettes. The current study extended previous work by conducting a comprehensive assessment of patterns and contexts of hookah use, psychological correlates of use, co-occurring substance use as well as social norms and health perceptions surrounding the practice. Participants were 143 ethnically diverse undergraduate students at a large urban US university. Approximately half of the sample (48%) reported life-time use of hookah and 22% reported use within the past 30days. Relative to cigarette smoking, hookah smoking was associated with less perceived harm and addiction potential and higher social approval. Participants who reported life-time hookah use, as compared to those who did not, perceived less associated harm, had a greater number of friends who had tried and approved of hookah, were more likely to use cigarettes, marijuana, and alcohol and in higher frequencies and quantities and were at higher risk for problem tobacco and alcohol use. Among participants who were not current smokers, those with hookah experience were more likely to endorse intent to try a cigarette soon. Hookah users did not differ from non-users on measures of trait anxiety, depression and impulsivity though they were more likely to drink alcohol for coping, social and enhancement purposes than non-users. Implications are discussed for public health initiatives to educate young adults about the potential consequences of hookah smoking. Descriptors Links Book Title Database Publisher Elsevier Ltd Data Source Authors Heinz,A.J., Giedgowd,G.E., Crane,N.A., Veilleux,J.C., Conrad,M., Braun,A.R., Olejarska,N.A., Kassel,J.D. Original/Translated Title URL Date of Electronic 20130723 PMCID Editors
A competitive quantitative polymerase chain reaction method for characterizing the population dynamics during kimchi fermentation	2015	Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, 151-921, South Korea.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of industrial microbiology & biotechnology Periodical, Abbrev. J.Ind.Microbiol.Biotechnol. Pub Date Free Form Jan Volume 42 Issue 1 Start Page 49 Other Pages 55 Notes JID: 9705544; 0 (DNA Primers); 0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S); 2014/09/21 [received]; 2014/11/19 [accepted]; 2014/12/05 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1476-5535; 1367-5435 Accession Number PMID: 25475752 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1007/s10295-014-1553-x [doi] Output Language Unknown(0) PMID 25475752 Abstract The aim of this study was to develop a competitive quantitative-PCR (CQ-PCR) method for rapid analysis of the population dynamics of lactic acid bacteria (LAB) in kimchi. For this, whole chromosome sequences of Leuconostoc mesenteroides, Lactobacillus plantarum, and Lb. brevis were compared and species-specific PCR primers targeting dextransucrase, 16S rRNA, and surface layer protein D (SlpD) genes, respectively, were constructed. The tested strains were quantified both in medium and kimchi by CQ-PCR and the results were compared with the data obtained using a conventional plate-counting method. As a result, the three species were successfully detected and quantified by the indicated primer sets. Our results show that the CQ-PCR method targeting species-specific genes is suitable for rapid estimation of LAB population to be used in the food fermentation industry. Descriptors Links Book Title Database Publisher Data Source Authors Ahn,G.H., Moon,J.S., Shin,S.Y., Min,W.K., Han,N.S., Seo,J.H. Original/Translated Title URL Date of Electronic 20141205 PMCID Editors
A comparison of the periodontal status in patients with mucous membrane pemphigoid: a 5-year follow-up	2009	Department of Periodontics, Baylor College of Dentistry, The Texas A&M Health Science Center, Dallas, TX 75246, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of periodontology Periodical, Abbrev. J.Periodontol. Pub Date Free Form Nov Volume 80 Issue 11 Start Page 1765 Other Pages 1773 Notes JID: 8000345; ppublish Place of Publication United States ISSN/ISBN 1943-3670; 0022-3492 Accession Number PMID: 19905946 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; D; IM DOI 10.1902/jop.2009.090244 [doi] Output Language Unknown(0) PMID 19905946 Abstract BACKGROUND: Mucous membrane pemphigoid (MMP) is a heterogeneous group of blistering autoimmune disorders of unknown etiology. Intraoral manifestations of MMP feature the formation of vesiculobullous lesions that eventually rupture, leading to pseudomembrane-covered, irregularly-shaped ulcerations. The presence of these often painful oral lesions may hinder oral hygiene efforts resulting in increased plaque accumulation and may increase the risk of developing periodontal disease. The purpose of this study was to evaluate the changes in periodontal status in patients with MMP after a period of 5 years. METHODS: Twenty patients, 10 diagnosed with MMP and 10 controls matched for age, gender, and smoking history, were chosen to participate in a study evaluating their periodontal status. Parameters evaluated included the plaque index, gingival index, bleeding index, probing depths, recession, clinical attachment level, mobility, furcation involvement, number of missing teeth, and periodontitis. Data from the same MMP and control patients were available for comparison from an identical baseline evaluation performed 5 years earlier. RESULTS: Patients with MMP exhibited a statistically significant higher gingival index and amount of lingual gingival recession at both time periods compared to controls. Both groups exhibited statistically significant increases in attachment loss and facial/lingual recession, but the difference in change between groups was not statistically significant. CONCLUSIONS: The results of this study suggest that patients diagnosed with MMP appear to be no more at risk than controls matched for age, gender, and smoking history in developing or having an increased progression of periodontal disease. Descriptors Aged, Aged, 80 and over, Case-Control Studies, Dental Plaque Index, Disease Progression, Female, Follow-Up Studies, Furcation Defects/classification, Gingival Hemorrhage/classification, Gingival Recession/classification, Humans, Male, Middle Aged, Pemphigoid, Benign Mucous Membrane/drug therapy/physiopathology, Periodontal Attachment Loss/classification, Periodontal Diseases/classification, Periodontal Index, Periodontal Pocket/classification, Periodontitis/classification, Risk Factors, Smoking, Tooth Loss/classification, Tooth Mobility/classification Links Book Title Database Publisher Data Source Authors Schellinck,A. E., Rees,T. D., Plemons,J. M., Kessler,H. P., Rivera-Hidalgo,F., Solomon,E. S. Original/Translated Title URL Date of Electronic PMCID Editors

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