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A study of carboxyhaemoglobin levels of cigarette and sheesha smokers in Saudi Arabia. 1982 Zahran, F.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Public Health
Periodical, Abbrev.
Am.J.Public Health
Pub Date Free Form
/
Volume
72
Issue
7
Start Page
722
Other Pages
724
Notes
Place of Publication
ISSN/ISBN
0090-0036
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
A single carboxyhaemoglobin (COHb) estimation of late evening blood sample among non-smokers, cigarette smokers, and sheesha smokers was evaluated among Saudis. The COHb level in smokers of 15 to 40 cigarettes a day ranged between 0.7 and 10.3 with a mean value of 6.1 +/- 2.58 COHb. Values among sheesha smokers ranged between 6.5 and 13.9 with a mean value of 8.8 +/- 1.83, significantly higher than those of cigarette smokers (P less than 0.001) for a given degree of exposure to tobacco smoke.
Descriptors
carboxyhemoglobin, hemoglobin, adult, article, comparative study, human, male, middle aged, Saudi Arabia, smoking, time
Links
Book Title
Database
MEDLINE
Publisher
Data Source
Embase
Authors
Zahran,F., Yousef,A. A., Baig,M. H.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A specific pharmacophore model of Aurora B kinase inhibitors and virtual screening studies based on it 2009 State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Sichuan 610041, China.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Chemical biology & drug design
Periodical, Abbrev.
Chem.Biol.Drug Des.
Pub Date Free Form
Jan
Volume
73
Issue
1
Start Page
115
Other Pages
126
Notes
LR: 20131121; JID: 101262549; EC 2.7.11.1 (AURKB protein, human); EC 2.7.11.1 (Aurora Kinase B); EC 2.7.11.1 (Aurora Kinases); EC 2.7.11.1 (Protein-Serine-Threonine Kinases); ppublish
Place of Publication
England
ISSN/ISBN
1747-0285; 1747-0277
Accession Number
PMID: 19152640
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1111/j.1747-0285.2008.00751.x [doi]
Output Language
Unknown(0)
PMID
19152640
Abstract
In this study, 3D-pharmacophore models of Aurora B kinase inhibitors have been developed by using HipHop and HypoGen modules in Catalyst software package. The best pharmacophore model, Hypo1, which has the highest correlation coefficient (0.9911), consists of one hydrogen-bond acceptor, one hydrogen-bond donor, one hydrophobic aliphatic moiety and one ring aromatic feature. Hypo1 was validated by test set and cross-validation methods. And the specificity of Hypo1 to Aurora B inhibitors was examined with the use of selective inhibitors against Aurora B and its paralogue Aurora A. The results clearly indicate that Hypo1 can differentiate selective inhibitors of Aurora B from those of Aurora A, and the ring aromatic feature likely plays some important roles for the specificity of Hypo1. Then Hypo1 was used as a 3D query to screen several databases including Specs, NCI, Maybridge and Chinese Nature Product Database (CNPD) for identifying new inhibitors of Aurora B. The hit compounds were subsequently subjected to filtering by Lipinski's rule of five and docking studies to refine the retrieved hits, and some compounds selected from the top ranked hits have been suggested for further experimental assay studies.
Descriptors
Aurora Kinase B, Aurora Kinases, Computer Simulation, Drug Design, Drug Evaluation, Preclinical/methods, Humans, Inhibitory Concentration 50, Models, Molecular, Molecular Structure, Protein-Serine-Threonine Kinases/antagonists & inhibitors/chemistry, Reproducibility of Results, Software, Structure-Activity Relationship
Links
Book Title
Database
Publisher
Data Source
Authors
Wang,H. Y., Li,L. L., Cao,Z. X., Luo,S. D., Wei,Y. Q., Yang,S. Y.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A solid-phase microextraction platinized stainless steel fiber coated with a multiwalled carbon nanotube-polyaniline nanocomposite film for the extraction of thymol and carvacrol in medicinal plants and honey 2015 Department of Chemistry, Lorestan University, Khoramabad, Iran. Electronic address: a_ghiasvand@yahoo.com.; Department of Chemistry, Lorestan University, Khoramabad, Iran.; Department of Chemistry, Lorestan University, Khoramabad, Iran.; Department of Che
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
7-Aug
Volume
1406
Issue
Start Page
87
Other Pages
93
Notes
CI: Copyright (c) 2015; JID: 9318488; 0 (Aniline Compounds); 0 (Monoterpenes); 0 (Nanotubes, Carbon); 0 (Water Pollutants, Chemical); 0 (polyaniline); 12597-68-1 (Stainless Steel); 3J50XA376E (Thymol); 9B1J4V995Q (carvacrol); OTO: NOTNLM; 2015/04/09 [rece
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 26138604
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.chroma.2015.06.052 [doi]
Output Language
Unknown(0)
PMID
26138604
Abstract
A mechanically hard and cohesive porous fiber, with large surface area, for more strong attachment of the coating was provided by platinizing a stainless steel wire. Then, the platinized stainless steel fiber was coated with a multiwalled carbon nanotube/polyaniline (MWCNT/PANI) nanocomposite using electrophoretic deposition (EPD) method and applied for the extraction of thymol and carvacrol with direct-immersion solid-phase microextraction (DI-SPME) method followed by high-performance liquid chromatography-ultraviolet detection (HPLC-UV) quantification. To provide a larger coarse surface for the tightened attachment of coating on the fiber, a stainless steel wire was platinized using a suitable optimized EPD method. Different experimental parameters were studied and the optimal conditions were obtained as: pH of the sample solution: 2; extraction time: 60min; salt content in the sample solution: 1% w/v NaNO3; desorption time: 60min; type and volume of the desorption solvent: acetonitrile, 100muL. Under the optimized conditions, limits of detection (LODs) were 0.6 and 0.8mugmL(-1) for thymol and carvacrol, respectively. Linear dynamic range (LDR) for the calibration curves of both analytes were 1-80mugmL(-1). Relative standard deviation (RSD%, n=6) was 6.8 for thymol and 12.7 for carvacrol. The proposed fiber was successfully applied for the recovery and determination of thymol and carvacrol in thyme, savory, and honey samples.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Ghiasvand,A., Dowlatshah,S., Nouraei,N., Heidari,N., Yazdankhah,F.
Original/Translated Title
URL
Date of Electronic
20150625
PMCID
Editors
A solid-phase microextraction fiber with carbon nanoparticles as sorbent material prepared by a simple flame-based preparation process 2013 Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sunmin-123456@163.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
26-Jul
Volume
1300
Issue
Start Page
173
Other Pages
179
Notes
CI: Copyright (c) 2013; JID: 9318488; 0 (Environmental Pollutants); 0 (Phthalic Acids); 0 (Polycyclic Hydrocarbons, Aromatic); 12597-68-1 (Stainless Steel); 660YQ98I10 (Potassium Chloride); 7440-44-0 (Carbon); OTO: NOTNLM; 2013/02/22 [received]; 2013/04/1
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 23684146
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.chroma.2013.04.061 [doi]
Output Language
Unknown(0)
PMID
23684146
Abstract
A novel carbon nanoparticles-coated solid-phase microextraction (SPME) fiber was prepared via a simple and low-cost flame-based preparation process, with stainless steel wire as support. Surface characteristic of the fiber was studied with scanning electron microscope. A nano-scaled brushy structure was observed. Coupled to gas chromatography (GC), the fiber was used to extract phthalate esters (PAEs) and polycyclic aromatic hydrocarbons (PAHs) in aqueous samples. Analytical performances of the proposed method were investigated under the optimum extraction conditions (extraction temperature, 40 degrees C; content of KCl, 30% (w/v); extraction time, 50min for PAEs and 40min for PAHs) and compared with other reports for the same analytes. Calibration ranges were 0.06-500mugL(-1) for di-n-butyl phthalate (DBP), and 0.1-300mugL(-1) for di-cyclohexyl phthalate (DCHP) and di-(2-ethyl-hexyl) phthalate (DEHP). For the eight PAHs, good linearity was obtained ranging from 0.01 to 150mugL(-1). Limits of detection were 0.005mugL(-1) for three PAEs and 0.001-0.003mugL(-1) for eight PAHs. The fiber exhibited excellent stability. It can be used for 100 times with RSDs of extraction efficiency less than 22.4%. The as-established SPME-GC method was applied to determine PAEs in food-wrap and PAHs in cigarette ash and snow water, and satisfactory results were obtained. The carbon nanoparticles-coated SPME fiber was efficient for sampling of organic compounds from aqueous samples.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Sun,M., Feng,J., Qiu,H., Fan,L., Li,L., Luo,C.
Original/Translated Title
URL
Date of Electronic
20130428
PMCID
Editors
A skim milk stabilized water vaccine for Newcastle disease (B1-type LaSota): its effectiveness under modern commercial cage layer methods of delivery. 1975 Woodward, H.L.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Poultry science
Periodical, Abbrev.
Poult.Sci.
Pub Date Free Form
/
Volume
54
Issue
3
Start Page
866
Other Pages
871
Notes
Place of Publication
ISSN/ISBN
0032-5791
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
For flock vaccination, B1-type LaSota Newcastle disease water vaccine was used in chicken under commercial cage layer conditions using two different methods, Swish Corporation pipes and cups, and stainless stell troughs, in an effort to determine their effectiveness. The concentration of virus in trough and cup samples collected at the beginning and the end of the lines were the same except in one instance where little or no virus was transported to the end of the trough. Satisfactory results were obtained when the test was repeated a year later. Serum HI titers determined before and after vaccination demonstrated adequate flock serum titers and indicated that both methods of application were reasonably effective. In laboratory trials, different water pipes (black, polyvinyl chloride pipe and Hart cups, green, polyvinyl chloride pipe and Swish cups, and old, rusty, galvanized pipe) normally used in cage operations were tested. Our findings indicated that dried skim milk powder (DSMP) was essential in stabilizing vaccine virus in the containers tested and that an adequate vaccine virus concentration was maintained in the three types of pipe tested when DSMP was used. Without DSMP the vaccine titers were adversely affected.
Descriptors
virus vaccine, water, animal, animal housing, article, bird disease, chicken, fat intake, hemagglutination inhibition test, immunology, milk, Newcastle disease virus, oral drug administration, procedures, temperature
Links
Book Title
Database
MEDLINE
Publisher
Data Source
Embase
Authors
Woodward,H. L., Tudor,D. C.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A single air dive reduces arterial endothelial function in man 2005 Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway. alfb@ntnu.no
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of physiology
Periodical, Abbrev.
J.Physiol.
Pub Date Free Form
1-Aug
Volume
566
Issue
Pt 3
Start Page
901
Other Pages
906
Notes
LR: 20140606; JID: 0266262; 0 (Gases); OID: NLM: PMC1464788; 2005/06/16 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
0022-3751; 0022-3751
Accession Number
PMID: 15961424
Language
eng
SubFile
Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
jphysiol.2005.089862 [pii]
Output Language
Unknown(0)
PMID
15961424
Abstract
During and after decompression from dives, gas bubbles are regularly observed in the right ventricular outflow tract. A number of studies have documented that these bubbles can lead to endothelial dysfunction in the pulmonary artery but no data exist on the effect of diving on arterial endothelial function. The present study investigated if diving or oxygen breathing would influence endothelial arterial function in man. A total of 21 divers participated in this study. Nine healthy experienced male divers with a mean age of 31 +/- 5 years were compressed in a hyperbaric chamber to 280 kPa at a rate of 100 kPa min(-1) breathing air and remaining at pressure for 80 min. The ascent rate during decompression was 9 kPa min(-1) with a 7 min stop at 130 kPa (US Navy procedure). Another group of five experienced male divers (31 +/- 6 years) breathed 60% oxygen (corresponding to the oxygen tension of air at 280 kPa) for 80 min. Before and after exposure, endothelial function was assessed in both groups as flow-mediated dilatation (FMD) by ultrasound in the brachial artery. The results were compared to data obtained from a group of seven healthy individuals of the same age who had never dived. The dive produced few vascular bubbles, but a significant arterial diameter increase from 4.5 +/- 0.7 to 4.8 +/- 0.8 mm (mean +/- s.d.) and a significant reduction of FMD from 9.2 +/- 6.9 to 5.0 +/- 6.7% were observed as an indication of reduced endothelial function. In the group breathing oxygen, arterial diameter increased significantly from 4.4 +/- 0.3 mm to 4.7 +/- 0.3 mm, while FMD showed an insignificant decrease. Oxygen breathing did not decrease nitroglycerine-induced dilatation significantly. In the normal controls the arterial diameter and FMD were 4.1 +/- 0.4 mm and 7.7 +/- 0.2.8%, respectively. This study shows that diving can lead to acute arterial endothelial dysfunction in man and that oxygen breathing will increase arterial diameter after return to breathing air. Further studies are needed to determine if these mechanisms are involved in tissue injury following diving.
Descriptors
Adult, Decompression Sickness/etiology/prevention & control, Diving/adverse effects/physiology, Endothelium, Vascular/physiology, Gases/blood, Humans, Male, Pulmonary Artery/physiology
Links
Book Title
Database
Publisher
Data Source
Authors
Brubakk,A. O., Duplancic,D., Valic,Z., Palada,I., Obad,A., Bakovic,D., Wisloff,U., Dujic,Z.
Original/Translated Title
URL
Date of Electronic
20050616
PMCID
PMC1464788
Editors
A simple system to study the effect of sheesha smoke on animal models 1986 College of Medicine and Allied Sciences, King Abdulaziz University, Jeddah
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Saudi medical journal
Periodical, Abbrev.
Saudi Med.J.
Pub Date Free Form
1986/
Volume
7
Issue
5
Start Page
451
Other Pages
454
Notes
Place of Publication
ISSN/ISBN
0379-5284
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
carbon monoxide, hemoglobin, animal model, control group, intoxication, nonhuman, rat, tobacco
Links
Book Title
Database
Embase
Publisher
Data Source
Embase
Authors
Sulaiman,M. I., Ardawi,M. S. M., Al-Fayz,S., Zahran,F. M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A simple snare for restraining cats 1981 Div. Lab. Anim. Resources, South. Illinois Univ. Sch. Med., Springfield, IL 62708
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Laboratory animal science
Periodical, Abbrev.
Lab.Anim.Sci.
Pub Date Free Form
1981/
Volume
31
Issue
6
Start Page
721
Other Pages
722
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
A simple, lightweight cat snare was constructed from rope and plastic water pipe and pipe fittings. The device was useful for cats, allowing effective restraint without injury.
Descriptors
cat, methodology, restraining device, theoretical study
Links
Book Title
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
Fisk,S. K.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A serological survey on viral haemorrhagic fevers in Liberia 1982 Dep. Med., Bernhard-Nocht-Inst. Schiffs- Tropenkr., Hamburg
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Annales de Virologie
Periodical, Abbrev.
ANN.VIROL.
Pub Date Free Form
1982/
Volume
133
Issue
2
Start Page
125
Other Pages
128
Notes
Place of Publication
ISSN/ISBN
0242-5017
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
The results demonstrate that Lassa fever is endemic in Liberia. Consistent with the occurrence of active Lassa fever cases, the prevalent Lassa virus activity seems to be in Lofa County and neighbouring Guinea. Statistically, medical personnel exposed to Lassa fever patients are not at a higher risk for Lassa virus infection than the general population. The higher level of contact with active cases incurred by the medical profession may be compensated by the usually higher standards of hygiene in the dwellings of such personnel and a concomitant lowered exposure to the natural host (Mastomys natalensis). Convincing conclusions concerning the endemic areas of the three viruses studied were complicated by the movements of the tested persons within Liberia and neighbouring Guinea. However, the fact that Lassa, Ebola and Marburg virus antibodies never appeared in the same serum sample leads one to theorize that the endemic regions of the three viruses are well-separated from each other. Consistent with this finding is the statistically significant different distribution of Lassa and Ebola virus antibody carriers, at least between Lofa County and Bong County. The broad age distribution of persons tested and the wide range of antibody titres observed for the activity of the three viruses suggest that the respective diseases probably occur more frequently in single cases rather than in occasional nosocomial or local epidemics. Considering that active cases of Ebola or Marburg virus disease have never been reported from Liberia, the occurrence of these specific antibodies was surprising. The results seem to indicate that Liberia has to be included in the Ebola and Marburg virus endemic zone. Therefore, the medical personnel in Liberian health centres should be aware of the possibility that they may come across active cases and thus be prepared to avoid nosocomial epidemics. Recent investigations doubt the specificity of the indirect immunofluorescence antibody test concerning Ebola and Marburg viruses (K.M. Johnson, personal communication). Thus the significance of the antibodies to Ebola and Marburg viruses identified in Liberia requires further evaluation.
Descriptors
virus antibody, epidemiology, geographic distribution, human cell, Lassa virus, Marburgvirus, serology
Links
Book Title
Database
Embase
Publisher
Data Source
Embase
Authors
Knobloch,J., Albiez,E. J., Schmitz,H.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A scoping review of the evidence on health promotion interventions for reducing waterpipe smoking: implications for practice 2018
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Frontiers in public health
Periodical, Abbrev.
Pub Date Free Form
Volume
6
Issue
Start Page
Other Pages
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
Frontiers Media SA
Data Source
google
Authors
Gardner, Karen, Kearns, Rachael, Woodland, Lisa, Silveira, Mariela, Hua, Myna, Katz, Milena, Takas, Klara, McDonald, Julie
Original/Translated Title
URL
Date of Electronic
PMCID
Editors