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Electronic cigarette use in young people in Great Britain 2013-2014 2015 Public Health England, London, United Kingdom; Addictions Department, Institute of Psychiatry, Psychology and Neurosciences, King's College London, United Kingdom. Electronic address: Brian.Eastwood@phe.gov.uk.; Public Health England, London, United Kingd
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Public health
Periodical, Abbrev.
Public Health
Pub Date Free Form
Sep
Volume
129
Issue
9
Start Page
1150
Other Pages
1156
Notes
CI: Crown Copyright (c) 2015; JID: 0376507; OTO: NOTNLM; 2015/02/09 [received]; 2015/07/06 [revised]; 2015/07/13 [accepted]; 2015/08/17 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1476-5616; 0033-3506
Accession Number
PMID: 26293814
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.puhe.2015.07.009 [doi]
Output Language
Unknown(0)
PMID
26293814
Abstract
OBJECTIVES: The recent growth in the market for electronic cigarettes (e-cigarettes) has led to concerns over their use by young people. It is therefore important to examine trends in the perception and use of e-cigarettes and conventional cigarettes in this group. STUDY DESIGN: Two-wave cross-sectional survey design. METHODS: Young people aged 11-18 in Great Britain were surveyed online by YouGov in 2013 and 2014. Use of e-cigarettes, together with perceived health harms and intention to use were assessed and compared in relation to cigarette smoking history, age and gender. RESULTS: Ever-use of e-cigarettes increased significantly from 4.6% (95% CI 3.8-5.7) in 2013 to 8.2% (95% CI 7.0-9.6) in 2014. Monthly or more use of e-cigarettes increased from 0.9% (95% CI 0.5-1.5) to 1.7 (1.2-2.4), but remained rare in never-smokers at under 0.2%. The proportion of young people who perceived e-cigarettes to be less harmful to users than cigarettes fell from 73.4% (95% CI 71.0-75.8) to 66.9% (95% CI 64.5-69.2), while the proportion who considered e-cigarettes to cause similar levels of harm increased from 11.8% (95% CI 10.0-13.5) to 18.2% (95% CI 16.3-20.1). Of the 8.2% of e-cigarette ever-users in 2014, 69.8% (95% CI 62.2%-77.3%) had smoked a cigarette prior to using an e-cigarette, while 8.2% (95% CI 4.1%-12.2%) first smoked a cigarette after e-cigarette use. CONCLUSIONS: A growing proportion of young people in Great Britain believe e-cigarettes are as harmful as smoking tobacco. Use of e-cigarettes by young people is increasing, but is largely confined to those who smoke.
Descriptors
Links
Book Title
Database
Publisher
. Published by Elsevier Ltd
Data Source
Authors
Eastwood,B., Dockrell,M.J., Arnott,D., Britton,J., Cheeseman,H., Jarvis,M.J., McNeill,A.
Original/Translated Title
URL
Date of Electronic
20150817
PMCID
Editors
Toxicant inhalation among singleton waterpipe tobacco users in natural settings 2019 Public Health Policy Evaluation Unit, Imperial College London, Hammersmith, UK.; Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.; Center for the Study of Tobacco Products, Virginia Commonwealth University, Ri(TRUNCATED
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Mar
Volume
28
Issue
2
Start Page
181
Other Pages
188
Notes
LR: 20190614; CI: (c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019; GR: P50 DA036105/DA/NIDA NIH HHS/United States; GR: R01 DA025659/DA/NIDA NIH HHS/United States; JID: 9209612; NIHMS971077; OTO: NOTNLM;
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 29807946
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
DOI
10.1136/tobaccocontrol-2017-054230 [doi]
Output Language
Unknown(0)
PMID
29807946
Abstract
BACKGROUND: Studies that assess waterpipe tobacco smoking behaviour and toxicant exposure generally use controlled laboratory environments with small samples that may not fully capture real-world variability in human behaviour and waterpipe products. This study aimed to conduct real-time sampling of waterpipe tobacco use in natural environments using an in situ device. METHODS: We used the REALTIME sampling instrument: a validated, portable, self-powered device designed to sample automatically a fixed percentage of the aerosol flowing through the waterpipe mouthpiece during every puff. We recruited participants at cafe and home settings in Jordan and measured puffing behaviour in addition to inhalation exposure of total particulate matter (TPM), carbon monoxide (CO), nicotine, polycyclic aromatic hydrocarbons and volatile aldehydes. We correlated total inhaled volume with five selected toxicants and calculated the regression line of this relationship. RESULTS: Averaged across 79 singleton sessions (52% male, mean age 27.0, 95% home sessions), sessions lasted 46.9 min and participants drew 290 puffs and inhaled 214 L per session. Mean quantities of inhaled toxicants per session were 1910 mg TPM, 259 mg CO, 5.0 mg nicotine, 117 ng benzo[a]pyrene and 198 ng formaldehyde. We found positive correlations between total inhaled volume and TPM (r=0.472; p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Jawad,M., Eissenberg,T., Salman,R., Soule,E., Alzoubi,K.H., Khabour,O.F., Karaoghlanian,N., Baalbaki,R., El Hage,R., Saliba,N.A., Shihadeh,A.
Original/Translated Title
URL
Date of Electronic
20180528
PMCID
PMC6563915
Editors
Toxicant inhalation among singleton waterpipe tobacco users in natural settings 2019 Public Health Policy Evaluation Unit, Imperial College London, Hammersmith, UK.; Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.; Center for the Study of Tobacco Products, Virginia Commonwealth University, Ri(TRUNCATED
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Mar
Volume
28
Issue
2
Start Page
181
Other Pages
188
Notes
LR: 20190614; CI: (c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019; GR: P50 DA036105/DA/NIDA NIH HHS/United States; GR: R01 DA025659/DA/NIDA NIH HHS/United States; JID: 9209612; NIHMS971077; OTO: NOTNLM;
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 29807946
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
DOI
10.1136/tobaccocontrol-2017-054230 [doi]
Output Language
Unknown(0)
PMID
29807946
Abstract
BACKGROUND: Studies that assess waterpipe tobacco smoking behaviour and toxicant exposure generally use controlled laboratory environments with small samples that may not fully capture real-world variability in human behaviour and waterpipe products. This study aimed to conduct real-time sampling of waterpipe tobacco use in natural environments using an in situ device. METHODS: We used the REALTIME sampling instrument: a validated, portable, self-powered device designed to sample automatically a fixed percentage of the aerosol flowing through the waterpipe mouthpiece during every puff. We recruited participants at cafe and home settings in Jordan and measured puffing behaviour in addition to inhalation exposure of total particulate matter (TPM), carbon monoxide (CO), nicotine, polycyclic aromatic hydrocarbons and volatile aldehydes. We correlated total inhaled volume with five selected toxicants and calculated the regression line of this relationship. RESULTS: Averaged across 79 singleton sessions (52% male, mean age 27.0, 95% home sessions), sessions lasted 46.9 min and participants drew 290 puffs and inhaled 214 L per session. Mean quantities of inhaled toxicants per session were 1910 mg TPM, 259 mg CO, 5.0 mg nicotine, 117 ng benzo[a]pyrene and 198 ng formaldehyde. We found positive correlations between total inhaled volume and TPM (r=0.472; p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Jawad,M., Eissenberg,T., Salman,R., Soule,E., Alzoubi,K.H., Khabour,O.F., Karaoghlanian,N., Baalbaki,R., El Hage,R., Saliba,N.A., Shihadeh,A.
Original/Translated Title
URL
Date of Electronic
20180528
PMCID
PMC6563915
Editors
Toxicant inhalation among singleton waterpipe tobacco users in natural settings 2019 Public Health Policy Evaluation Unit, Imperial College London, Hammersmith, UK.; Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.; Center for the Study of Tobacco Products, Virginia Commonwealth University, Ri(TRUNCATED
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Mar
Volume
28
Issue
2
Start Page
181
Other Pages
188
Notes
LR: 20190425; CI: (c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019; GR: P50 DA036105/DA/NIDA NIH HHS/United States; GR: R01 DA025659/DA/NIDA NIH HHS/United States; JID: 9209612; OTO: NOTNLM; 2017/12/29 0
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 29807946
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
DOI
10.1136/tobaccocontrol-2017-054230 [doi]
Output Language
Unknown(0)
PMID
29807946
Abstract
BACKGROUND: Studies that assess waterpipe tobacco smoking behaviour and toxicant exposure generally use controlled laboratory environments with small samples that may not fully capture real-world variability in human behaviour and waterpipe products. This study aimed to conduct real-time sampling of waterpipe tobacco use in natural environments using an in situ device. METHODS: We used the REALTIME sampling instrument: a validated, portable, self-powered device designed to sample automatically a fixed percentage of the aerosol flowing through the waterpipe mouthpiece during every puff. We recruited participants at cafe and home settings in Jordan and measured puffing behaviour in addition to inhalation exposure of total particulate matter (TPM), carbon monoxide (CO), nicotine, polycyclic aromatic hydrocarbons and volatile aldehydes. We correlated total inhaled volume with five selected toxicants and calculated the regression line of this relationship. RESULTS: Averaged across 79 singleton sessions (52% male, mean age 27.0, 95% home sessions), sessions lasted 46.9 min and participants drew 290 puffs and inhaled 214 L per session. Mean quantities of inhaled toxicants per session were 1910 mg TPM, 259 mg CO, 5.0 mg nicotine, 117 ng benzo[a]pyrene and 198 ng formaldehyde. We found positive correlations between total inhaled volume and TPM (r=0.472; p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Jawad,M., Eissenberg,T., Salman,R., Soule,E., Alzoubi,K.H., Khabour,O.F., Karaoghlanian,N., Baalbaki,R., El Hage,R., Saliba,N.A., Shihadeh,A.
Original/Translated Title
URL
Date of Electronic
20180528
PMCID
Editors
Price elasticity of demand of non-cigarette tobacco products: a systematic review and meta-analysis 2018 Public Health Policy Evaluation Unit, Imperial College London, London, UK.; Public Health Policy Evaluation Unit, Imperial College London, London, UK.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Melbourn(TRUNCATED
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Nov
Volume
27
Issue
6
Start Page
689
Other Pages
695
Notes
LR: 20190426; CI: (c) Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018; GR: R01 DA043950/DA/NIDA NIH HHS/United States; GR: RP_2014-04-032/Department of Health/United Kingdom; JID: 9209612; NIHMS957362; OTO:
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 29363611
Language
eng
SubFile
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Systematic Review; IM
DOI
10.1136/tobaccocontrol-2017-054056 [doi]
Output Language
Unknown(0)
PMID
29363611
Abstract
OBJECTIVE: To systematically review the price elasticity of demand of non-cigarette tobacco products. DATA SOURCES: Medline, Embase, EconLit and the Web of Science without language or time restrictions. STUDY SELECTION: Two reviewers screened title and abstracts, then full texts, independently and in duplicate. We based eligibility criteria on study design (interventional or observational), population (individuals or communities without geographic restrictions), intervention (price change) and outcome (change in demand). DATA EXTRACTION: We abstracted data on study features, outcome measures, statistical approach, and single best own- and cross-price elasticity estimates with respect to cigarettes. We conducted a random effects meta-analysis for estimates of similar product, outcome and country income level. For other studies we reported median elasticities by product and country income level. DATA SYNTHESIS: We analysed 36 studies from 15 countries yielding 125 elasticity estimates. A 10% price increase would reduce demand by: 8.3% for cigars (95% CI 2.9 to 13.8), 6.4% for roll your owns (95% CI 4.3 to 8.4), 5.7% for bidis (95% CI 4.3 to 7.1) and 2.1% for smokeless tobacco (95% CI -0.6 to 4.8). Median price elasticities for all ten products were also negative. Results from few studies that examined cross-price elasticity suggested a positive substitution effect between cigarette and non-cigarette tobacco products. CONCLUSIONS: There is sufficient evidence in support of the effectiveness of price increases to reduce consumption of non-cigarette tobacco products as it is for cigarettes. Positive substitutability between cigarette and non-cigarette tobacco products suggest that tax and price increases need to be simultaneous and comparable across all tobacco products.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Jawad,M., Lee,J.T., Glantz,S., Millett,C.
Original/Translated Title
URL
Date of Electronic
20180123
PMCID
PMC6056338
Editors
Types of tobacco consumption and the oral microbiome in the United Arab Emirates Healthy Future (UAEHFS) Pilot Study 2018 Public Health Research Center, New York University Abu Dhabi, Abu Dhabi, UAE.; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi, UAE.; Department of Population Health, New York University School of Medicine, New York, USA.(TRUNCATED
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Scientific reports
Periodical, Abbrev.
Sci.Rep.
Pub Date Free Form
27-Jul
Volume
8
Issue
1
Start Page
11327
Other Pages
018-29730-x
Notes
LR: 20181114; JID: 101563288; 2017/11/23 00:00 [received]; 2018/06/27 00:00 [accepted]; 2018/07/29 06:00 [entrez]; 2018/07/29 06:00 [pubmed]; 2018/07/29 06:00 [medline]; epublish
Place of Publication
England
ISSN/ISBN
2045-2322; 2045-2322
Accession Number
PMID: 30054546
Language
eng
SubFile
Journal Article
DOI
10.1038/s41598-018-29730-x [doi]
Output Language
Unknown(0)
PMID
30054546
Abstract
Cigarette smoking alters the oral microbiome; however, the effect of alternative tobacco products remains unclear. Middle Eastern tobacco products like dokha and shisha, are becoming globally widespread. We tested for the first time in a Middle Eastern population the hypothesis that different tobacco products impact the oral microbiome. The oral microbiome of 330 subjects from the United Arab Emirates Healthy Future Study was assessed by amplifying the bacterial 16S rRNA gene from mouthwash samples. Tobacco consumption was assessed using a structured questionnaire and further validated by urine cotinine levels. Oral microbiome overall structure and specific taxon abundances were compared, using PERMANOVA and DESeq analyses respectively. Our results show that overall microbial composition differs between smokers and nonsmokers (p = 0.0001). Use of cigarettes (p = 0.001) and dokha (p = 0.042) were associated with overall microbiome structure, while shisha use was not (p = 0.62). The abundance of multiple genera were significantly altered (enriched/depleted) in cigarette smokers; however, only Actinobacillus, Porphyromonas, Lautropia and Bifidobacterium abundances were significantly changed in dokha users whereas no genera were significantly altered in shisha smokers. For the first time, we show that smoking dokha is associated to oral microbiome dysbiosis, suggesting that it could have similar effects as smoking cigarettes on oral health.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Valles,Y., Inman,C.K., Peters,B.A., Ali,R., Wareth,L.A., Abdulle,A., Alsafar,H., Anouti,F.A., Dhaheri,A.A., Galani,D., Haji,M., Hamiz,A.A., Hosani,A.A., Houqani,M.A., Junaibi,A.A., Kazim,M., Kirchhoff,T., Mahmeed,W.A., Maskari,F.A., Alnaeemi,A., Oumeziane,N., Ramasamy,R., Schmidt,A.M., Weitzman,M., Zaabi,E.A., Sherman,S., Hayes,R.B., Ahn,J.
Original/Translated Title
URL
Date of Electronic
20180727
PMCID
PMC6063860
Editors
Hookah smoking and harm perception among asthmatic adolescents: findings from the Florida youth tobacco survey 2014 Public Health, Department of Health Sciences and Human Performance, The University of Tampa, 401 W. Kennedy Boulevard, Box 30F, Tampa, FL 33606.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of school health
Periodical, Abbrev.
J.Sch.Health
Pub Date Free Form
May
Volume
84
Issue
5
Start Page
334
Other Pages
341
Notes
CI: (c) 2014; JID: 0376370; OTO: NOTNLM; 2013/05/31 [received]; 2013/08/07 [revised]; 2013/11/09 [accepted]; ppublish
Place of Publication
United States
ISSN/ISBN
1746-1561; 0022-4391
Accession Number
PMID: 24707928
Language
eng
SubFile
Journal Article; IM; N
DOI
10.1111/josh.12153 [doi]
Output Language
Unknown(0)
PMID
24707928
Abstract
BACKGROUND: Hookah tobacco smoking has increased in prevalence among Florida adolescents and is often viewed as a safer alternative to cigarette smoking by young adults. Asthmatic adolescents are at increased risk of the negative health effects of hookah smoking. The purpose of this study is to examine if hookah use and harm perception vary by asthma status. METHODS: The Florida Youth Tobacco Survey was conducted in 2012 among 36,578 high school students. Secondary data analysis was conducted to compare the rates of hookah use among asthmatic youth to their nonasthmatic counterparts. Risk perception of hookah use compared to cigarette smoking was also assessed among asthmatic and nonasthmatic adolescents. RESULTS: One in 5 high school students reported lifetime asthma. These asthmatic students have a significantly higher prevalence of hookah smoking and greater perception of hookah use as being less harmful than cigarette smoking, than their nonasthmatic counterparts. Among asthmatics, 12th graders and Hispanic students had the highest prevalence of hookah smoking. CONCLUSION: Common misperceptions of hookah smoking as being less harmful than cigarette smoking are prominent among high school students in Florida and are greater among students with asthma than those students who do not have asthma. Efforts to increase education to dispel the myths surrounding hookah smoking as a safer alternative to cigarette smoking needs to exist at the high school level for both students with and without asthma.
Descriptors
Links
Book Title
Database
Publisher
American School Health Association
Data Source
Authors
Martinasek,M.P., Gibson-Young,L., Forrest,J.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Key design features of a new smokefree law to help achieve the Smokefree Aotearoa 2016 Public Health, University of Otago, Wellington.; Public Health, University of Otago, Wellington.; Public Health, University of Otago, Wellington.; Public Health, University of Otago, Wellington, New Zealand.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The New Zealand medical journal
Periodical, Abbrev.
N.Z.Med.J.
Pub Date Free Form
5-Aug
Volume
129
Issue
1439
Start Page
68
Other Pages
76
Notes
JID: 0401067; epublish
Place of Publication
New Zealand
ISSN/ISBN
1175-8716; 0028-8446
Accession Number
PMID: 27507723
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
27507723
Abstract
AIM: To design new tobacco control legislation to achieve the New Zealand Government's 2025 smokefree goal. METHOD: An original analysis of the legislative options for New Zealand tobacco control. RESULTS: 'Business as usual' is most unlikely to achieve smoking prevalence that is less than 5% by 2025. Key components of a new Act would ideally include plans and targets with teeth, a focus on the industry, a focus on the product, reduction of supply, and a whole-of-society approach to promote consistency in policy implementation through: i) a public duty on government agencies to act consistently with smokefree law; ii) a general duty on those associated with the tobacco/nicotine industry in relation to tobacco control objectives; and iii) a principle requiring international treaties to be interpreted consistently with tobacco control objectives. CONCLUSION: Strategies such as those identified in this Viewpoint should be explored further as part of urgently needed planning to achieve the New Zealand Government's goal for Smokefree Aotearoa by 2025.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Delany,L., Thomson,G., Wilson,N., Edwards,R.
Original/Translated Title
URL
Date of Electronic
20160805
PMCID
Editors
A magnetite suspension-based washing method for immunoassays using Escherichia coli cells with autodisplayed Z-domains 2016 Pyun, J.-C., Department of Materials Science and Engineering, Yonsei University, SeoulSouth Korea
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Enzyme and microbial technology
Periodical, Abbrev.
Enzyme Microb.Technol.
Pub Date Free Form
2016/10
Volume
92
Issue
Start Page
1
Other Pages
8
Notes
Place of Publication
ISSN/ISBN
1879-0909; 0141-0229
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Escherichia coli cells with autodisplayed Z-domains have been used for immunoassays of specific target analytes. In this study, a magnetite suspension was used for the washing step in immunoassays of E. coli cells with autodisplayed Z-domains. This approach enhanced the washing conditions for these immunoassays by determining (1) the optimal concentration of the magnetite suspension, (2) the capacity of the magnetite suspension-based washing method to recover E. coli cells, and (3) the level at which the activity of autodisplayed Z-domains is maintained. In immunoassays of C-reactive protein (CRP), the immunoassay incorporating the magnetite suspension-based washing method showed a sensitivity and limit of detection considerably higher than those of the conventional centrifugation-based washing method. The results indicated that immunoassays incorporating the magnetite suspension-based washing method are effective for medical diagnoses based on CRP assay.
Descriptors
Links
Book Title
Database
Embase
Publisher
Data Source
Embase
Authors
Kim,D.-H., Bong,J.-H., Yoo,G., Chang,S.-Y., Chang,Y.W., Kang,M.-J., Jose,J., Pyun,J.-C.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Comprehensive determination of polycyclic aromatic hydrocarbons in Chinese herbal medicines by solid phase extraction and gas chromatography coupled to tandem mass spectrometry 2015 Qinhuangdao Entry-Exit Inspection and Quarantine Bureau, Qinhuangdao, 066004, China.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Analytical and bioanalytical chemistry
Periodical, Abbrev.
Anal.Bioanal Chem.
Pub Date Free Form
Mar
Volume
407
Issue
7
Start Page
1989
Other Pages
1997
Notes
LR: 20160512; JID: 101134327; 0 (Drugs, Chinese Herbal); 0 (Polycyclic Hydrocarbons, Aromatic); 2014/10/17 [received]; 2015/01/05 [accepted]; 2014/12/19 [revised]; 2015/01/31 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1618-2650; 1618-2642
Accession Number
PMID: 25636228
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s00216-015-8463-2 [doi]
Output Language
Unknown(0)
PMID
25636228
Abstract
A simple and highly sensitive gas chromatography-tandem mass spectrometry (GC-MS/MS) method combined with solid-phase extraction cleanup was established for the comprehensive determination of 16 Environmental Protection Agency (EPA) polycyclic aromatic hydrocarbons (PAHs) in various kinds of Chinese herbal medicines (CHMs). A solid-phase extraction (SPE) purification strategy, including three parallel procedures, was developed depending on sample type, and satisfactory purification performances were achieved for all selected CHMs. The limits of detection ranged from 0.12 to 1.08 mug kg(-1) for the analyzed PAHs. The average recoveries were in the range of 65.9 % to 100.8 %, except for naphthalene (43.8 %-75.9 %), and the relative standard deviations were =12.8 %. The proposed method was successfully applied to the analysis of PAHs in 24 CHMs including five roots, three stems, four flowers, two fruits, four seeds, three leaves, and three barks. In the samples analyzed, all 16 PAHs are present. Their sum ranges from 21.1 to 2236.3 mug kg(-1). The entire procedure was shown to be effective and conveniently fast, and may serve as an alternative screening protocol for the determination of PAHs in CHMs.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Cui,Z., Ge,N., Zhang,A., Liu,Y., Zhang,J., Cao,Y.
Original/Translated Title
URL
Date of Electronic
20150131
PMCID
Editors