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Tensile bond strength of dentin adhesives on acid- and laser-etched dentin surfaces 2009 Renident Dental Clinic, Istanbul, Turkey. bilgetarcin@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Quintessence international (Berlin, Germany : 1985)
Periodical, Abbrev.
Quintessence Int.
Pub Date Free Form
Nov-Dec
Volume
40
Issue
10
Start Page
865
Other Pages
874
Notes
LR: 20131121; JID: 0342677; 0 (Composite Resins); 0 (Dental Materials); 0 (Dentin-Bonding Agents); 0 (Methacrylates); 0 (OptiBond Solo Plus); 0 (Phosphoric Acids); 0 (Prodigy Condensable); 0 (Resin Cements); 0 (Siloxanes); 0 (Solvents); 0 (admira); 0 (adm
Place of Publication
Germany
ISSN/ISBN
1936-7163; 0033-6572
Accession Number
PMID: 19898719
Language
eng
SubFile
Comparative Study; Journal Article; Randomized Controlled Trial; D
DOI
17592 [pii]
Output Language
Unknown(0)
PMID
19898719
Abstract
OBJECTIVE: To evaluate tensile bond strengths of 2 dentin bonding agents containing solvents on Nd:YAG and Er,Cr:YSGG laser-etched dentin surface. METHOD AND MATERIALS: Occlusal enamel of 146 molars was removed, and exposed surfaces were ground with a diamond bur to produce bur-cut dentin surfaces. Of those teeth, 120 were assigned to 3 groups of 40 samples in which dentin was conditioned with Er,Cr:YSGG laser, Nd:YAG laser, and 37% orthophosphoric acid (control). Each group was further divided into 2 subgroups, acetone- and ethanol-containing bonding agents, and 4-mm-long x 4-mm-wide composite rods were bonded to all specimens using a Plexiglas mold. Tensile bond strength testing of 120 samples was performed at a crosshead speed of 0.5 mm/min using a 50-kgf load cell. The remaining 26 samples were examined under SEM to evaluate the adaptation/penetration of the bonding materials and the alterations in mineral content. Data were analyzed using 1-way ANOVA and Kruskal-Wallis tests; P < .05 was considered statistically significant. RESULTS: The difference between the mean tensile bond strength values obtained with bonding agents was statistically significant in the control group. The bond strength values of the acetone-containing agent in this group were found to be higher than the ethanol-containing agent (P < .001). When compared with Nd:YAG laser, bond strength values obtained with Er,Cr:YSGG laser were higher (P < .001). The bond strength values obtained in the acid-etched group were highest for both bonding agents and demonstrated statistical significance (P < .001). CONCLUSION: Although in this study laser etching is more influential than the solvent type on bond strengths of dentin bonding agents, it cannot be considered as an alternative to conventional acid etching.
Descriptors
Acetone/chemistry, Acid Etching, Dental/methods, Composite Resins/chemistry, Dental Bonding, Dental Etching/methods, Dental Materials/chemistry, Dental Stress Analysis/instrumentation, Dentin/ultrastructure, Dentin-Bonding Agents/chemistry, Ethanol/chemistry, Humans, Lasers, Solid-State, Materials Testing, Methacrylates/chemistry, Microscopy, Electron, Scanning, Phosphoric Acids/chemistry, Resin Cements/chemistry, Siloxanes/chemistry, Solvents/chemistry, Stress, Mechanical, Surface Properties, Tensile Strength
Links
Book Title
Database
Publisher
Data Source
Authors
Tarcin,B., Gunday,M., Ovecoglu,H. S., Turkmen,C., Ovecoglu,M. L., Oksuz,M., Ay,M.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Tensile bond strength of Er,Cr:YSGG laser-irradiated human dentin and analysis of dentin-resin interface 2007 Graduate Institute of Clinical Dentistry, College of Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Dental materials : official publication of the Academy of Dental Materials
Periodical, Abbrev.
Dent.Mater.
Pub Date Free Form
May
Volume
23
Issue
5
Start Page
570
Other Pages
578
Notes
LR: 20131121; JID: 8508040; 0 (Composite Resins); 0 (Dentin-Bonding Agents); 0 (Methacrylates); 0 (One Coat Bond); 0 (Resin Cements); 0 (palfique estelite); 059QF0KO0R (Water); 2005/07/05 [received]; 2006/03/06 [revised]; 2006/03/09 [accepted]; 2006/07/03
Place of Publication
England
ISSN/ISBN
0109-5641; 0109-5641
Accession Number
PMID: 16820200
Language
eng
SubFile
Journal Article; D
DOI
S0109-5641(06)00104-7 [pii]
Output Language
Unknown(0)
PMID
16820200
Abstract
OBJECTIVES: As the bond strength of composite resin to Er,Cr:YSGG laser-irradiated dentin has not yet been evaluated, the objectives of this study were to investigate the tensile bond strength and to analyze the resin-dentin interface among bur-cut/acid-etched, Er,Cr:YSGG laser-ablated/acid-etched and Er,Cr:YSGG laser-ablated human dentin. METHODS: Crown dentin disks prepared from extracted human third permanent molars were used for the observation of surface morphological changes by scanning electron microscope (SEM). The laser energy parameters were 3.5 W and 20 Hz with water spray (air pressure level, 80%; water pressure level, maximum level). Another group of crown dentin disks were prepared for composite resin restoration and observation of resin-dentin bond interface after demineralization in 6N hydrochloric acid (HCl) for 1 min and deproteinization in 1% sodium hypochlorite solution (NaOCl) for 10 min. The tensile bond strengths of the three groups were measured by a universal testing machine at a crosshead speed of 0.5 mm/min. Fracture types at the dentin-resin interface were analyzed using the digital stereoscopic microscope and fractured surfaces of the debonded specimens were examined by SEM. RESULTS: All three groups showed that the treated surfaces were free of dentin debris and smear layer. The peritubular dentin protruded from the surrounding intertubular dentin after laser irradiation. The dentin-resin interface treated with Er,Cr:YSGG laser irradiation and acid etching demonstrated numerous resin tags converging into a bulge and then diverging again. The length of resin tags was greater than 100 microm. The tensile bond strengths of bur-cut/acid-etched, laser-ablated/acid-etched and laser-ablated human dentin were 5.37+/-1.51, 5.17+/-1.41 and 3.29+/-0.86 MPa, respectively. No statistical significance was found between the bur-cut/acid-etched and laser-ablated/acid-etched groups. The predominant fracture modes of bur-cut/acid-etched, laser-ablated/acid-etched and laser-ablated human dentin were Type 1 (50%), Type 2 (70%) and Type 1 (70%), respectively. SIGNIFICANCE: Er,Cr:YSGG laser irradiation affects adversely adhesion of resin to dentin but acid etching following laser irradiation could increase the tensile bond strength as high as that of bur-cut/acid-etched human dentin.
Descriptors
Acid Etching, Dental, Adolescent, Adult, Composite Resins/chemistry, Dental Bonding, Dental Cavity Preparation/instrumentation/methods, Dentin/ultrastructure, Dentin-Bonding Agents/chemistry, Humans, Lasers, Materials Testing, Methacrylates/chemistry, Microscopy, Electron, Scanning, Resin Cements/chemistry, Smear Layer, Stress, Mechanical, Surface Properties, Tensile Strength, Water/chemistry
Links
Book Title
Database
Publisher
Data Source
Authors
Lee,B. S., Lin,P. Y., Chen,M. H., Hsieh,T. T., Lin,C. P., Lai,J. Y., Lan,W. H.
Original/Translated Title
URL
Date of Electronic
20060703
PMCID
Editors
Tensile bond strengths of five luting agents to two CAD-CAM restorative materials and enamel 2003 Department of Dental Public Health and Dental Hygiene, Houston Dental Branch, University of Texas, Houston, Texas, USA. Jeffrey.C.Chang@uth.tmc.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of prosthetic dentistry
Periodical, Abbrev.
J.Prosthet.Dent.
Pub Date Free Form
Jul
Volume
90
Issue
1
Start Page
18
Other Pages
23
Notes
LR: 20151119; JID: 0376364; 0 (Boron Compounds); 0 (Composite Resins); 0 (Dental Cements); 0 (Dicor ceramic); 0 (EnForce-Sure Cure); 0 (FujiPlus); 0 (Glass Ionomer Cements); 0 (Methacrylates); 0 (Methylmethacrylates); 0 (Panavia TPN-S); 0 (Phosphates); 0
Place of Publication
United States
ISSN/ISBN
0022-3913; 0022-3913
Accession Number
PMID: 12869970
Language
eng
SubFile
Journal Article; D; IM
DOI
10.1016/S0022391303002178 [doi]
Output Language
Unknown(0)
PMID
12869970
Abstract
STATEMENT OF PROBLEM: CAD-CAM restorative materials are popular because they have high esthetic value and short fabrication time. Unfortunately these materials are brittle and tend to fracture under heavy occlusal load. PURPOSE: The purpose of this in vitro study was to investigate the tensile bond strengths of 5 luting agents to 2 CAD-CAM restorative materials and enamel. Material and methods One hundred truncated cones, with a 3-mm diameter bonding surface and 5-mm diameter base, were fabricated with Dicor MGC (n=50) or Cerec Vitablocs Mark II (n=50) with the Cerec system. Enamel surfaces of the crowns of 100 freshly extracted noncarious, anterior teeth, stored in 0.9% saline solution with 0.25% sodium azide (NaN(3)) as disinfectant, were prepared with sandpaper disks (320-grit size) on the Buehler Variable Speed Grinder-Polisher. The bonding surfaces of the Dicor MGC or Cerec Vitablocs Mark II truncated cones from each of the 2 tests systems were airborne particle abraded, chemically etched, and cemented on the prepared enamel surface of the tooth specimens with 5 luting agents: Vita Cerec Duo Cement, EnForce, Panavia 21, C&B Metabond, and Fuji Duet. All specimens were thermocycled 1000 times, in 5 degrees C and 55 degrees C water with a dwell time of 30 seconds in each temperature. Tensile force (MPa) was applied perpendicular to the bonding surfaces of the specimens with a universal testing machine until fracture. Fracture patterns were examined with a microscope at original magnification x10. The differences in the tensile bond strengths were analyzed with the Tukey-Kramer test (alpha=.05). RESULTS: The mean tensile bond strengths of Dicor MGC bonding to enamel with luting agents in descending order in MPa were EnForce (10.12 +/- 2.25), Panavia 21 (7.28 +/- 1.77), Cerec Duo (5.32 +/- 1.65), Fuji Duet (3.73 +/- 1.78), and C&B Metabond (3.11 +/- 1.11). EnForce had a significantly higher bond strength than C&B Metabond, Fuji Duet, Cerec Duo, and Panavia 21 (P=.05). The mean tensile bond strengths of Cerec Vitablocs Mark II bonding to enamel with luting agents in descending order in MPa were as follow: Fuji Duet (11.51 +/- 2.79), EnForce (9.44 +/- 2.03), C&B Metabond (8.98 +/- 3.29), Cerec Duo (8.66 +/- 4.71), and Panavia 21 (5.10 +/- 2.49). Within this group, there was no significant difference between Fuji Duet and EnForce, but the bond strength of Fuji Duet was significantly higher than that of C&B Metabond, Panavia 21, and Cerec Duo (P=.05). The mean tensile strength of all the luting agents bonded to Cerec Vitablocs Mark II and enamel (8.74 MPa) was higher than Dicor MGC and enamel (5.91 MPa). CONCLUSION: In this in vitro study; within the Dicor MGC group, the mean bond strength of Panavia 21 with enamel was significantly higher than C&B Metabond, Panavia 21, Cerec Duo, and Fuji Duet. Within the Cerec Vitablocs Mark II group, the mean bond strength of Fuji Duet was significantly higher than C&B Metabond, Panavia 21, and Cerec Duo but was not significantly higher than EnForce.
Descriptors
Acid Etching, Dental, Bisphenol A-Glycidyl Methacrylate/chemistry, Boron Compounds/chemistry, Cementation, Ceramics/chemistry, Composite Resins/chemistry, Computer-Aided Design, Dental Bonding, Dental Cements/chemistry, Dental Enamel/ultrastructure, Dental Porcelain/chemistry, Dental Restoration, Permanent, Glass Ionomer Cements, Humans, Materials Testing, Methacrylates/chemistry, Methylmethacrylates/chemistry, Phosphates/chemistry, Resin Cements/chemistry, Stress, Mechanical, Surface Properties, Tensile Strength
Links
Book Title
Database
Publisher
Data Source
Authors
Chang,J. C., Hart,D. A., Estey,A. W., Chan,J. T.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Testing a process-based model of tree seedling growth by manipulating [CO2] and nutrient uptake 2000 Levy, P.E., Institute of Terrestrial Ecology, Penicuik, Midlothian EH26 0QB, United Kingdom
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tree physiology
Periodical, Abbrev.
Tree Physiol.
Pub Date Free Form
2000/
Volume
20
Issue
15
Start Page
993
Other Pages
1005
Notes
Place of Publication
ISSN/ISBN
0829-318X
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
A model was developed that simulated photosynthesis, growth and allocation in tree seedlings. The model was parameterized with data from experiments on seedlings of sycamore (Acer pseudoplatanus L.), Sitka spruce (Picea sitchensis (Bong) Carr.) and young birch trees (Betula pendula Roth.). In these experiments, CO2 concentration ([CO2]) and nutrient addition rate were varied. Parameters quantifying nutrient uptake, translocation and starch synthesis were fitted, based on data from control treatments. Elevated [CO2] and low-nutrient treatments were then used to test the predicted response of growth and allocation against observations. The model accurately predicted total seedling growth in the elevated [CO2] treatments. A response of growth to elevated [CO2] was seen in the birch and sycamore experiments, but not in the Sitka spruce, because of photosynthetic down-regulation. Predictions of allocation were reasonably accurate in the birch and Sitka spruce experiments, but were notably poorer in the sycamore experiments, possibly because of differences in sink strength between root and shoot. In the birch and sycamore experiments, little change in allocation with elevated [CO2] was observed or predicted. This was ascribed to the relative values of K(Tc) and K(Tn), the translocation coefficients that determine the sensitivity of allocation to carbon and nitrogen uptake rates, respectively. Growth and allocation in the low-nutrient treatments were poorly predicted by the model. In Sitka spruce, it was suspected that the photosynthetic parameters measured in August 1994 had been higher earlier in the season, before nutrients became depleted. In sycamore, the discrepancies were thought to relate to differences in sink strength between root and shoot that could not be described by the model.
Descriptors
carbon dioxide, article, biological model, down regulation, growth, development and aging, photosynthesis, physiology, plant leaf, plant root, plant stem, tree
Links
Book Title
Database
MEDLINE
Publisher
Data Source
Embase
Authors
Levy,P. E., Lucas,M. E., McKay,H. M., Escobar-Gutierrez,A. J., Rey,A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Testing antismoking messages for Air Force trainees 2015 Center for Tobacco Control Research and Education, University of California, San Francisco, California, USA.; Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Division of Biostatistics, Depa
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
19-Oct
Volume
Issue
Start Page
Other Pages
Notes
LR: 20160420; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: K99 CA187460/CA/NCI NIH HHS/United States; GR: R0
Place of Publication
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 26482786
Language
ENG
SubFile
JOURNAL ARTICLE
DOI
tobaccocontrol-2015-052477 [pii]
Output Language
Unknown(0)
PMID
26482786
Abstract
INTRODUCTION: Young adults in the military are aggressively targeted by tobacco companies and are at high risk of tobacco use. Existing antismoking advertisements developed for the general population might be effective in educating young adults in the military. This study evaluated the effects of different themes of existing antismoking advertisements on perceived harm and intentions to use cigarettes and other tobacco products among Air Force trainees. METHODS: In a pretest-post-test experiment, 782 Airmen were randomised to view antismoking advertisements in 1 of 6 conditions: anti-industry, health effects+anti-industry, sexual health, secondhand smoke, environment+anti-industry or control. We assessed the effect of different conditions on changes in perceived harm and intentions to use cigarettes, electronic cigarettes, smokeless tobacco, hookah and cigarillos from pretest to post-test with multivariable linear regression models (perceived harm) and zero-inflated Poisson regression model (intentions). RESULTS: Antismoking advertisements increased perceived harm of various tobacco products and reduced intentions to use. Advertisements featuring negative effects of tobacco on health and sexual performance coupled with revealing tobacco industry manipulations had the most consistent pattern of effects on perceived harm and intentions. CONCLUSIONS: Antismoking advertisements produced for the general public might also be effective with a young adult military population and could have spillover effects on perceptions of harm and intentions to use other tobacco products besides cigarettes. Existing antismoking advertising may be a cost-effective tool to educate young adults in the military.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Popova,L., Linde,B.D., Bursac,Z., Talcott,G.W., Modayil,M.V., Little,M.A., Ling,P.M., Glantz,S.A., Klesges,R.C.
Original/Translated Title
URL
Date of Electronic
20151019
PMCID
PMC4837096
Editors
Tetra-ethyl-ammonium l-malate 1.36-hydrate 2008
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
10-Dec
Volume
65
Issue
Pt 1
Start Page
o49
Other Pages
50
Notes
LR: 20130329; JID: 101089178; OID: NLM: PMC2967964; 2008/11/12 [received]; 2008/12/01 [accepted]; 2008/12/10 [epublish]; epublish
Place of Publication
England
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 21581690
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536808040348 [doi]
Output Language
Unknown(0)
PMID
21581690
Abstract
The asymmetric unit of the title compound, C(8)H(20)N(+).C(4)H(5)O(5) (-).1.36H(2)O, contains two independent ion pairs, with similar conformations, and three water mol-ecules of crystallization, one water mol-ecule haing a site-occupancy factor of 0.721 (5). Intra-molecular O-Hcdots, three dots, centeredO hydrogen bonds, involving the hydr-oxy groups and an O atom of each carboxyl-ate anion, generate five-membered rings involving S(5) ring motifs. In the crystal structure, mol-ecules are linked together by water mol-ecules through four-membered O-Hcdots, three dots, centeredO-Hcdots, three dots, centeredO-H inter-actions to form one-dimensional infinite chains along the a axis. Since the mol-ecules are also linked into one-dimensional infinite chains along the b axis, mol-ecular sheets parallel to the (001) plane are created. Overall, the crystal structure is stabilized by two intra-molecular O-Hcdots, three dots, centeredO hydrogen bonds, nine inter-molecular O-Hcdots, three dots, centeredO and ten C-Hcdots, three dots, centeredO hydrogen bonds.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Abdul Rahman,M. B., Jumbri,K., Sirat,K., Kia,R., Fun,H. K.
Original/Translated Title
URL
Date of Electronic
20081210
PMCID
PMC2967964
Editors
The 6-minute walk test in chronic respiratory failure: does observed or predicted walk distance better reflect patient functional status? 2013 Respiratory Intensive Care Unit, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey. drgokaygungor@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Respiratory care
Periodical, Abbrev.
Respir.Care
Pub Date Free Form
May
Volume
58
Issue
5
Start Page
850
Other Pages
857
Notes
JID: 7510357; ppublish
Place of Publication
United States
ISSN/ISBN
1943-3654; 0020-1324
Accession Number
PMID: 23107072
Language
eng
SubFile
Journal Article; Observational Study; IM
DOI
10.4187/respcare.02009 [doi]
Output Language
Unknown(0)
PMID
23107072
Abstract
BACKGROUND: Acquiring 6-min walk test (6MWT) data from patients undergoing noninvasive mechanical ventilation due to chronic hypercapnic respiratory failure is limited. We aimed to assess whether the actual 6-min walk distance (6MWD) or the percent predicted 6MWD is a better reflection of the respiratory function of patients using home noninvasive ventilation (NIV) due to chronic hypercapnic respiratory failure. METHODS: This was a cross-sectional observational study. The 6MWT was performed in subjects using home NIV. Diagnoses were grouped as COPD, obesity hypoventilation syndrome (OHS), kyphoscoliosis, and parenchymal lung disease. Sex, age, and body mass index (BMI) were used to calculate ideal 6MWD. Male: 1,140 m - (5.61 x BMI) - (6.94 x age), and subtract 153 m for the lower limit of normal. Female: 1,017 m - (6.24 x BMI) - (5.83 x age), and subtract 139 m for the lower limit of normal. The 6MWD and percent-of-predicted 6MWD were compared relative to arterial blood gas, spirometry values, and diagnosis. RESULTS: The 6MWT was performed in 144 subjects, median (IQR) age 62 y (55-71 y). The male/female ratio, median (IQR) 6MWD, and percent-of-predicted 6MWD values were: COPD 32/6, 316 m (226-390 m), and 59.4% (42.5-68.9%); OHS 24/28, 303 m (240-362 m), and 73.0% (63.0-82.0%); kyphoscoliosis 16/7, 420 m (318-462 m), and 70.5% (56.0-75.2%); and parenchymal lung disease 19/12, 333 m (273-372 m), and 67.1% (46.7-74.7%). The correlation of percent-of-predicted 6MWD with spirometry and arterial blood gas values were better than with the actual 6MWD. CONCLUSIONS: The percent-of-predicted 6MWD was better correlated with respiratory function than actual 6MWD for subjects using home NIV due to chronic hypercapnic respiratory failure with COPD, OHS, kyphoscoliosis, and parenchymal lung disease.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Gungor,G., Karakurt,Z., Adiguzel,N., Aydin,R.E., Balci,M.K., Salturk,C., Sancar,R., Solmaz,S., Mocin,O.Y.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates 2012 Departamento de Microbiologia e Parasitologia, Centro de Ciencias da Saude, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil. debora_alves6@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Memorias do Instituto Oswaldo Cruz
Periodical, Abbrev.
Mem.Inst.Oswaldo Cruz
Pub Date Free Form
May
Volume
107
Issue
3
Start Page
433
Other Pages
436
Notes
LR: 20141120; JID: 7502619; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Lipopeptides); 0 (Pyrimidines); 0 (Triazoles); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); 9HLM53094I (anidulafungin); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole);
Place of Publication
Brazil
ISSN/ISBN
1678-8060; 0074-0276
Accession Number
PMID: 22510843
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
S0074-02762012000300022 [pii]
Output Language
Unknown(0)
PMID
22510843
Abstract
The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C. glabrata has been less studied than other species. In this paper, we compared the activity of three major classes of antifungal agents (azoles, echinocandins and polyenes) against fluconazole-susceptible (FS) and fluconazole-resistant (FR) C. glabrata strains. Cross-resistance between fluconazole and voriconazole was remarkable. Among the antifungal agents, the echinocandins were the most effective against FS and FR C. glabrata and micafungin showed the lowest minimal inhibitory concentrations.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Mario,D.A., Denardi,L.B., Bandeira,L.A., Antunes,M.S., Santurio,J.M., Severo,L.C., Alves,S.H.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The acute effects of water-pipe smoking on the cardiorespiratory system 2011
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Chest
Periodical, Abbrev.
Chest
Pub Date Free Form
Volume
139
Issue
4
Start Page
775
Other Pages
81
Notes
ID: 21030492
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
OBJECTIVE: There are limited data on the acute effects of water-pipe tobacco smoking, commonly known as water-pipe smoking (WPS), on cardiopulmonary parameters. This study evaluated the acute effects of a single 30-min session of WPS on carboxyhemoglobin (COHb) levels, pulmonary function test results, vital signs, fractional exhaled nitric oxide (Feno) levels, and exhaled breath condensate (EBC) cytokine levels in volunteers in a domestic, open-air, group smoking setting. METHODS: This prospective study evaluated the above-noted outcome parameters before and after 30 min of WPS. The primary outcome parameter was the change in COHb levels. RESULTS: Forty-five volunteers (30 men, 15 women), aged 32.35 ± 15.33 years, were recruited. After one session of WPS, the COHb levels rose significantly, from 1.47% ± 0.57% (median 1.4) to 9.47% ± 5.52% (median 7.4), P < .001. Systolic and diastolic BP levels significantly increased after smoking (systolic, 119.52 ± 12.07 mm Hg vs 131.98 ± 17.8 mm Hg; diastolic, 74.84 ± 7.89 mm Hg vs 82.98 ± 12.52 mm Hg, respectively; P < .001). Heart rates increased from 80.39 ± 9.92 beats/min to 95.59 ± 17.41 beats/min, P < .001; and respiratory rates increased from 14.36 ± 1.63 breaths/min to 16.68 ± 2.24 breaths/min, P < .001. There were decreases in forced expiratory flow between 25% and 75% of FVC, peak expiratory flow rate, Feno levels, percentage of eosinophils in peripheral blood, and 8-isoprostane levels in EBC. CONCLUSIONS: This study shows that one session of WPS causes acute biologic changes that might result in marked health problems. It adds to the limited evidence that WPS is harmful and supports interventions to control the continuing global spread of WPS, especially among youth. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT01157832; URL: www.clinicaltrials.gov.
Descriptors
Blood Pressure/physiology, Cardiovascular System/physiopathology, Forced Expiratory Flow Rates/physiology, Respiratory System/physiopathology, Smoking/adverse effects, Tars/adverse effects, Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Prognosis, Respiratory Function Tests, Risk Factors, Tobacco, Young Adult
Links
http://dx.doi.org/10.1378/chest.10-1833
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Hakim,Fahed, Hellou,Elias, Goldbart,Aviv, Katz,Rina, Bentur,Yedidia, Bentur,Lea
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The acute effects of waterpipe smoking on lung function and exercise capacity in a pilot study of healthy participants 2013
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Inhal Toxicol
Periodical, Abbrev.
Inhal.Toxicol.
Pub Date Free Form
Volume
25
Issue
9
Start Page
492
Other Pages
7
Notes
ID: 23905967
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
CONTEXT: Waterpipe tobacco smoking (WTS) has gained popularity, but its physiologic effects have not been extensively studied: rather, studies have focused on WTS's chronic effects or have evaluated limited respiratory/cardiac parameters. OBJECTIVE: We sought to characterize in a more detailed manner the acute effects of WTS on lung function and exercise capacity. METHOD: We recruited 24 healthy WTS males. We used a pilot single-group pre-test (abstained from WTS for ≥48 h) post-test (within 0.5 h of a 45-min WTS session) design. We performed spirometry, diffusing lung capacity and time-limited CPE testing (CPET; cycloergometer; 2-min 20-Watt warm-up and 25-Watt increase every 2-min for 10 min). RESULTS: Mean age was 20.4 years; Post-WTS, the following significant changes were observed: CO level increased from 3.7 ppm to 24.4; oxygen consumption decreased (from 1.86 L/min to 1.7); baseline respiratory rate increased (from 17.7 breath/min to 19.7); forced expiratory flow over the middle half of the forced vital capacity decreased (from 5.51 L to 5.29); and perceived exertion (measured by Borg scale) at mid and peak exercise increased. Baseline resting systolic blood pressure, pulse pressure, and pulse pressure product increased post-WTS (from 118.9 mmHg to 129.2; from 45.3 mmHg to 55.6; and from 9.9 mmHg/min to 11.1 post-WTS, respectively). During exercise, a decrease in oxygen pulse was observed post-WTS (from 10.89 ml/beat to 9.97), while the heart rate-oxygen consumption relationship increased post-WTS (from 3.52 beats/ml/kg to 3.91). CONCLUSION: Acute WTS appears to induce impairment in lung function and exercise capacity. Larger studies are warranted to further characterize the nature and extent of such impairment.
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http://dx.doi.org/10.3109/08958378.2013.806613
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MEDLINE; http://www.globalhealthlibrary.net/
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Hawari,Feras I., Obeidat,Nour A., Ayub,Hiba, Ghonimat,Iyad, Eissenberg,Thomas, Dawahrah,Sahar, Beano,Hamza
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