WTS database

Title Sort descending	Pub Year	Author	SearchLink
Technical note: a double L intestinal cannula for cattle.	1991	Streeter, M.N., Oklahoma State University, Stillwater 74078-0425.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of animal science Periodical, Abbrev. J.Anim.Sci. Pub Date Free Form / Volume 69 Issue 6 Start Page 2601 Other Pages 2607 Notes Place of Publication ISSN/ISBN 0021-8812 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract A double L-shaped intestinal cannula was developed in an attempt to overcome problems observed previously with simple T-type cannulas. The cannula was constructed from cyclopolyvinyl chloride water pipe fittings. Construction materials were fairly rigid, but by connecting the split cannula pieces with elastic castration bands the cannula had some flexibility. Placing a short cone over the exposed cannula barrel reduced mechanical damage to the intestine. The double L cannula required a much smaller incision in the intestine during surgical insertion than a T-type cannula; it also simplified replacement. Construction is described; use and performance of the cannula has been satisfactory. Descriptors animal, animal disease, article, catheterization, bovine, digestion, duodenum, eating, female, ileum, intestine, laboratory diagnosis, male, physiology, weight gain Links Book Title Database MEDLINE Publisher Data Source Embase Authors Streeter,M. N., Barron,S. J., Wagner,D. G., Hibberd,C. A., Owens,F. N., McCollum,F. T. Original/Translated Title URL Date of Electronic PMCID Editors
Technoeconomic and environmental assessment of industrial organotin compounds	1984	Midwest Research Institute, Kansas City, MO 64110	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Neurotoxicology Periodical, Abbrev. Neurotoxicology Pub Date Free Form 1984/ Volume 5 Issue 2 Start Page 141 Other Pages 158 Notes Place of Publication ISSN/ISBN 0161-813X Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Current uses of organotins include heat stabilizers for polyvinyl chloride (PVC), catalysts for polyurethane foam and silicone rubber, biocides, and animal health products. Domestic production consumption in 1982 is about 28 million pounds, and overall growth is estimated at 7 percent per year. Physical properties of organotins, including solubility in water, octanol-water partition coefficients, and Freundlich adsorption isotherm constants, are not well characterized. Analytical methods for tin in environmental and biological matrices involve concentration, separation, and identification by chromatography, spectrometry, and spectroscopy. Environmental fate and effects of organotins are not well understood. Degradation reactions may yield a complex set of products, including inorganic tin oxide. The effects of exposure of workers and release of organotins to the environment at point sources have been documented. Nonpoint sources of environmental exposure include discard and sanitary landfill disposal of plastics and direct release of biocides to aquatic or marine environments. Other dissipative uses of organotins which pose potential human risk include PVC food wrapping and bottles and rigid potable water pipe. The long term health effects of low level exposure to organotins are not known. Toxic metal cycling in the environment, including biomethylation of inorganic tin by naturally occurring bacteria, is of rising concern. Descriptors drinking water, organotin compound, plastic, rubber, economic aspect, food packaging, health hazard, human, intoxication, occupational exposure, toxin analysis Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Wilkinson,R. R. Original/Translated Title URL Date of Electronic PMCID Editors
Teen use of flavored tobacco products in new york city	2014	Bureau of Chronic Disease Prevention and Tobacco Control, New York City Department of Health and Mental Hygiene, Queens, NY sfarley@health.nyc.gov.; Bureau of Chronic Disease Prevention and Tobacco Control, New York City Department of Health and Mental Hy	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Periodical, Abbrev. Nicotine Tob.Res. Pub Date Free Form Nov Volume 16 Issue 11 Start Page 1518 Other Pages 1521 Notes CI: Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco 2014; JID: 9815751; 0 (Flavoring Agents); 1490-04-6 (Menthol); 2014/07/31 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-994X; 1462-2203 Accession Number PMID: 25082831 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/ntr/ntu126 [doi] Output Language Unknown(0) PMID 25082831 Abstract INTRODUCTION: Teen use of flavored tobacco products is a concern. Menthol cigarettes have been found to influence teen smoking; however, less is known about the association between teen use of other flavored tobacco products, such as cigars and dip, and cigarette smoking. METHODS: The New York City 2010 Special Communities Putting Prevention to Work Youth Risk Behavior Survey data (N = 1,800 aged 13-17 years) were analyzed to examine the association between ever trying flavored tobacco products and current smoking, after we adjusted for demographics and ever-use of menthol cigarettes. RESULTS: Twenty percent of teens reported ever trying flavored tobacco products; youth who were current smokers (58%) were more likely to have tried flavored tobacco products than youth who were not current smokers (16%). Controlling for menthol cigarette use, teens who had ever tried flavored tobacco products were nearly 3 times more likely to be current smokers than those who had never tried flavored tobacco products (odds ratio = 2.70, 95% confidence interval = 1.47-4.98). CONCLUSIONS: Ever trying flavored tobacco products was strongly associated with current smoking among teens. The findings from this study suggest that regulations prohibiting sales of flavored tobacco products could decrease youth smoking. Descriptors Links Book Title Database Publisher . This work is written by (a) US Government employee(s) and is in the public domain in the US Data Source Authors Farley,S.M., Seoh,H., Sacks,R., Johns,M. Original/Translated Title URL Date of Electronic 20140731 PMCID Editors
Telephone counselling for smoking cessation	2013	Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, UK, OX2 6GG.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Cochrane database of systematic reviews Periodical, Abbrev. Cochrane Database Syst.Rev. Pub Date Free Form 12-Aug Volume (8):CD002850. doi Issue 8 Start Page CD002850 Other Pages Notes LR: 20160602; JID: 100909747; epublish Place of Publication England ISSN/ISBN 1469-493X; 1361-6137 Accession Number PMID: 23934971 Language eng SubFile Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; IM DOI 10.1002/14651858.CD002850.pub3 [doi] Output Language Unknown(0) PMID 23934971 Abstract BACKGROUND: Telephone services can provide information and support for smokers. Counselling may be provided proactively or offered reactively to callers to smoking cessation helplines. OBJECTIVES: To evaluate the effect of proactive and reactive telephone support via helplines and in other settings to help smokers quit. SEARCH METHODS: We searched the Cochrane Tobacco Addiction Group Specialised Register for studies of telephone counselling, using search terms including 'hotlines' or 'quitline' or 'helpline'. Date of the most recent search: May 2013. SELECTION CRITERIA: randomized or quasi-randomised controlled trials in which proactive or reactive telephone counselling to assist smoking cessation was offered to smokers or recent quitters. DATA COLLECTION AND ANALYSIS: One author identified and data extracted trials, and a second author checked them. The main outcome measure was the risk ratio for abstinence from smoking after at least six months follow-up. We selected the strictest measure of abstinence, using biochemically validated rates where available. We considered participants lost to follow-up to be continuing smokers. Where trials had more than one arm with a less intensive intervention we used only the most similar intervention without the telephone component as the control group in the primary analysis. We assessed statistical heterogeneity amongst subgroups of clinically comparable studies using the I(2) statistic. We considered trials recruiting callers to quitlines separately from studies recruiting in other settings. Where appropriate, we pooled studies using a fixed-effect model. We used a meta-regression to investigate the effect of differences in planned number of calls, selection for motivation, and the nature of the control condition (self help only, minimal intervention, pharmacotherapy) in the group of studies recruiting in non-quitline settings. MAIN RESULTS: Seventy-seven trials met the inclusion criteria. Some trials were judged to be at risk of bias in some domains but overall we did not judge the results to be at high risk of bias. Among smokers who contacted helplines, quit rates were higher for groups randomized to receive multiple sessions of proactive counselling (nine studies, > 24,000 participants, risk ratio (RR) for cessation at longest follow-up 1.37, 95% confidence interval (CI) 1.26 to 1.50). There was mixed evidence about whether increasing the number of calls altered quit rates but most trials used more than two calls. Three studies comparing different counselling approaches during a single quitline contact did not detect significant differences. Of three studies that tested the provision of access to a hotline two detected a significant benefit and one did not.Telephone counselling not initiated by calls to helplines also increased quitting (51 studies, > 30,000 participants, RR 1.27; 95% CI 1.20 to 1.36). In a meta-regression controlling for other factors the effect was estimated to be slightly larger if more calls were offered, and in trials that specifically recruited smokers motivated to try to quit. The relative extra benefit of counselling was smaller when it was provided in addition to pharmacotherapy (usually nicotine replacement therapy) than when the control group only received self-help material or a brief intervention.A further eight studies were too diverse to contribute to meta-analyses and are discussed separately. Two compared different intensities of counselling, both of which detected a dose response; one of these detected a benefit of multiple counselling sessions over a single call for people prescribed bupropion. The others tested a variety of interventions largely involving offering telephone counselling as part of a referral or systems change and none detected evidence of effect. AUTHORS' CONCLUSIONS: Proactive telephone counselling aids smokers who seek help from quitlines. Telephone quitlines provide an important route of access to support for smokers, and call- Descriptors Links Book Title Database Publisher Data Source Authors Stead,L.F., Hartmann-Boyce,J., Perera,R., Lancaster,T. Original/Translated Title URL Date of Electronic 20130812 PMCID Editors
Temperature effects on nitrogen form uptake by seedling roots of three contrasting conifers	2014	Centre for Forest Biology, University of Victoria, PO Box 3020, STN CSC, Victoria, BC, Canada V8W 3N5.; Centre for Forest Biology, University of Victoria, PO Box 3020, STN CSC, Victoria, BC, Canada V8W 3N5 bhawkins@uvic.ca.; Centre for Forest Biology, Uni	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tree physiology Periodical, Abbrev. Tree Physiol. Pub Date Free Form May Volume 34 Issue 5 Start Page 513 Other Pages 523 Notes LR: 20151119; CI: (c) The Author 2014; JID: 100955338; 0 (Soil); N762921K75 (Nitrogen); OTO: NOTNLM; 2014/05/14 [aheadofprint]; ppublish Place of Publication Canada ISSN/ISBN 1758-4469; 0829-318X Accession Number PMID: 24831958 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/treephys/tpu028 [doi] Output Language Unknown(0) PMID 24831958 Abstract Plant species may show a preference for uptake of particular nitrogen (N) forms, but little is known about how N form preference is influenced by soil temperature. Potential future changes in soil N form availability and plant N form preference in warmer soils might shift competitive interactions among forest tree species. We compared the N uptake and growth of three conifer species from contrasting environments grown at rhizosphere temperatures of 10, 16 or 20 degrees C and supplied with ammonium (NH4 (+)) or nitrate (NO3 (-)) or a mix of arginine and alanine. Short-term N uptake was assessed using ion-selective microelectrodes and application of (15)N, and long-term uptake was assessed by plant N status. Species exhibited preferences for particular N forms, and these preferences related to the N form most available in native soils. Specifically, Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) showed a preference for nitrate (a N form commonly found in warmer areas), Sitka spruce (Picea sitchensis (Bong.) Carr.) preferred ammonium (a N form abundant in cold soils) and Engelmann spruce (Picea engelmannii Parry ex Engelm.) showed a preference for ammonium and organic N (organic N is often abundant in cold soils). Relative N form preference, as indicated by plant growth, changed with temperature in some species, indicating that these species could acclimate to changing rhizosphere temperatures. Understanding how conifers utilize available soil nutrients at different temperatures can help to predict species' future performance as soil temperatures rise. Descriptors Links Book Title Database Publisher . Published by Oxford University Press Data Source Authors Boczulak,S.A., Hawkins,B.J., Roy,R. Original/Translated Title URL Date of Electronic 20140514 PMCID Editors
Temporal and spatial distribution of BTEX pollutants in the atmosphere of metropolitan areas and neighbouring towns	2009	Department of Environmental Sciences, Second University of Naples, Caserta, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Environmental monitoring and assessment Periodical, Abbrev. Environ.Monit.Assess. Pub Date Free Form Mar Volume 150 Issue 4-Jan Start Page 437 Other Pages 444 Notes LR: 20131121; JID: 8508350; 0 (Air Pollutants); 0 (Benzene Derivatives); 0 (Xylenes); 3FPU23BG52 (Toluene); J64922108F (Benzene); L5I45M5G0O (ethylbenzene); 2007/07/12 [received]; 2008/02/27 [accepted]; 2008/04/25 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1573-2959; 0167-6369 Accession Number PMID: 18437518 Language eng SubFile Journal Article; IM DOI 10.1007/s10661-008-0242-5 [doi] Output Language Unknown(0) PMID 18437518 Abstract Atmospheric BTEX [benzene, toluene, ethylbenzene, o-xylene and (m + p)-xylene] concentrations have been determined in the Naples metropolitan area (NMA) and in two suburban areas located on the north within about 25 km, during 2006. The pollutants were collected by passive samplers (24-h samplings), and analysed by GC-MS. In all the areas analysed the average atmospheric benzene concentrations were higher than the limit value fixed by the European Union for 2010 and in NMA the average concentration (9.8 microg m(-3)) also exceeded the limit fixed for 2006. High linear correlation coefficients between the average daily concentrations of the different BTEX are indicative of a single major source, most likely the vehicular traffic. The temporal and spatial distribution of BTEX relative concentrations suggest that massive emissions in NMA negatively affect the quality of the air in northern suburban areas, prevalently during the hottest months of the year, probably due to transport by local seasonal winds. The ratios between BTEX daily concentrations showed a clear dependence on the intensity of solar actinic flow, indicating a major role of photochemical processes in the air cleaning from these volatile organic pollutants. Descriptors Air Pollutants/analysis, Atmosphere, Benzene/analysis, Benzene Derivatives/analysis, Cities, Environmental Monitoring, Humans, Italy, Toluene/analysis, Urban Health, Wind, Xylenes/analysis Links Book Title Database Publisher Data Source Authors Iovino,P., Polverino,R., Salvestrini,S., Capasso,S. Original/Translated Title URL Date of Electronic 20080425 PMCID Editors
Temporal Change of Alcian Blue-Stained Primo Vascular System in Lymph Vessels of Rats	2016	Nano Primo Research Center, Advanced Institute of Convergence Technology, Seoul National University, Suwon, 443-270, South Korea.; Nano Primo Research Center, Advanced Institute of Convergence Technology, Seoul National University, Suwon, 443-270, South K	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Advances in Experimental Medicine and Biology Periodical, Abbrev. Adv.Exp.Med.Biol. Pub Date Free Form Volume 923 Issue Start Page 311 Other Pages 317 Notes JID: 0121103; OTO: NOTNLM; ppublish Place of Publication United States ISSN/ISBN 0065-2598; 0065-2598 Accession Number PMID: 27526158 Language eng SubFile Journal Article; IM DOI 10.1007/978-3-319-38810-6_41 [doi] Output Language Unknown(0) PMID 27526158 Abstract This study aims to investigate the temporal change of a vascular system now known as the primo vascular system (PVS). We used Alcian blue (AB) dye for imaging the distribution of the PVS in lymphatic vessels. The target lymph vessels were chosen as they are easily accessible from the skin, and long-term observation is possible with intact physiological conditions due to a minimal surgical procedure. AB solution was injected into the inguinal lymph node and the target lymph vessels were located along the superficial epigastric vessels. The imaging system allowed processing for extraction of images showing changes in the AB intensity of the visualized PVS components. This newly developed procedure can be used for further study on various dynamic processes of PVS in lymph vessels. Descriptors Links Book Title Database Publisher Data Source Authors Kim,J., Kim,D.H., Jung,S.J., Soh,K.S. Original/Translated Title URL Date of Electronic PMCID Editors
Temporal distribution, behaviour and reactivities of BTEX compounds in a suburban Atlantic area during a year	2009	Department of Analytical Chemistry, University of A Coruna, Campus da Zapateira s/n, E-15071 A Coruna, Spain.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of environmental monitoring : JEM Periodical, Abbrev. J.Environ.Monit. Pub Date Free Form Jun Volume 11 Issue 6 Start Page 1216 Other Pages 1225 Notes LR: 20131121; JID: 100968688; 0 (Air Pollutants); 0 (Benzene Derivatives); 0 (Vehicle Emissions); 0 (Xylenes); 3FPU23BG52 (Toluene); J64922108F (Benzene); L5I45M5G0O (ethylbenzene); 2009/04/02 [aheadofprint]; 2009/06/01 [epublish]; ppublish Place of Publication England ISSN/ISBN 1464-0333; 1464-0325 Accession Number PMID: 19513453 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1039/b819370c [doi] Output Language Unknown(0) PMID 19513453 Abstract The temporal distribution of BTEX compounds (benzene, toluene, ethylbenzene and xylene isomers) in ambient air was studied in a suburban Atlantic area in the northwest of Spain. These compounds mean serious risks for public and occupational health and for biological and physical environments. A total of 1200 samples were analysed during a year, and in most of the samples toluene was the most abundant VOC followed by benzene or m+p-xylene. The average concentrations were 1.62, 2.15, 0.60, 0.94 and 0.47 microg m(-3) for benzene, toluene, ethylbenzene, m+p-xylenes and o-xylene respectively, although they reached values as high as 50.53, 28.57, 21.33, 46.13 and 22.74 microg m(-3) for the compounds in the same order. An exhaustive study was carried out to establish how both emission sources and the climatic conditions affected the BTEX levels measured in the outskirts of a small city. Wind directions and speeds, daily and seasonal BTEX profiles, ratios among the concentrations measured in the sampling site, in the city centre and in the fuels commonly used by the cars in the city were studied. The pollution roses revealed the presence of diffuse BTEX sources affecting the sampling point, although all the compounds reached their highest levels when the wind blew from an industrial area in the SW of the city. The daily BTEX profiles were well-correlated with the traffic pattern in the accesses to the city and the seasonal profile showed that the highest concentrations were reported in summertime. The ratios T/B, m+p-X/B and o-X/B were 1.32, 0.58 and 0.29 respectively; these values were lower than the ones reported in previous studies carried out in the centre of the same city. This could be caused by the major distance from the sampling point to the city centre and by the changes in the fuels and in the kind of vehicles used in the city. The correlation coefficients among the TEX fraction were always higher than 0.72 but benzene only showed a good correlation with these compounds in winter. The correlations between BTEX concentrations and their contributions to the photochemistry in the sampling area were used in order to evaluate the distance from the road traffic source and to estimate the presence of fresh or old air masses in the sampling point. This study provides data which can be useful to establish the BTEX levels in suburban areas from the coastal Atlantic region and improves the knowledge of the BTEX presence in this kind of area. Descriptors Air Pollutants/analysis, Atmosphere, Benzene/analysis, Benzene Derivatives/analysis, Cities, Environmental Monitoring, Humans, Seasons, Spain, Suburban Health, Temperature, Toluene/analysis, Vehicle Emissions/analysis, Volatilization, Wind, Xylenes/analysis Links Book Title Database Publisher Data Source Authors Perez-Rial,D., Lopez-Mahia,P., Muniategui-Lorenzo,S., Prada-Rodriguez,D. Original/Translated Title URL Date of Electronic 20090402 PMCID Editors
Temporal trends in the relative prevalence of dysphagia etiologies from 1999-2009	2012	Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full World journal of gastroenterology Periodical, Abbrev. World J.Gastroenterol. Pub Date Free Form 28-Aug Volume 18 Issue 32 Start Page 4335 Other Pages 4341 Notes LR: 20151022; JID: 100883448; 0 (Proton Pump Inhibitors); OID: NLM: PMC3436048; OTO: NOTNLM; 2012/06/06 [received]; 2012/07/30 [revised]; 2012/08/03 [accepted]; ppublish Place of Publication China ISSN/ISBN 2219-2840; 1007-9327 Accession Number PMID: 22969196 Language eng SubFile Comparative Study; Journal Article; IM DOI 10.3748/wjg.v18.i32.4335 [doi] Output Language Unknown(0) PMID 22969196 Abstract AIM: To examine the relative prevalence and temporal variation of dysphagia etiologies in patients undergoing upper endoscopy (EGD) over the past decade. METHODS: EGDs with the indication of dysphagia at an urban, university medical center in 1999, 2004 and 2009 were retrospectively identified from the electronic medical record. The entire patient chart, including EGD, pathology, manometry, radiographic and clinician reports, was reviewed for demographic and clinical data and to determine the etiology of dysphagia. The number of EGDs in which an esophageal biopsy was performed was also noted. Gastroesophageal reflux disease (GERD) as a cause of dysphagia independent of peptic stricture was defined by symptoms with erosive esophagitis or symptom response to proton pump inhibition (PPI). Cases of eosinophilic esophagitis (EoE) were defined by an appropriate clinical history and histological criteria of >/= 15 eosinophils per high powered field. PPI-responsive esophageal eosinophilia was not routinely reported prior to 2008. Statistical analysis was performed using one-way analysis of variance to analyze for trends between 1999, 2004 and 2009 and a post-hoc Tukey analysis was performed following a significant main effect. RESULTS: A total of 1371 cases (mean age 54 years, 43% male) met pre-specified inclusion criteria with 191, 504 and 675 cases in 1999, 2004 and 2009, respectively. Patients were older in 2004 compared to 2009 (mean +/- SD, 54.0 +/- 15.7 years vs 52.3 +/- 16.8 years, P = 0.02) and there were more males in 1999 compared to 2004 (57.5% vs 40.8%, P = 0.005). Overall, GERD (27.6%) and EoE (7.7%) were the most common identifiable causes of dysphagia. An unspecified diagnosis accounted for 21% of overall cases. There were no significant differences in the relative prevalence of achalasia or other motility disorders, peptic stricture, Schatzki's ring, esophageal cancer or unspecified diagnoses over the 10-year time period. There was, however, a decrease in the relative prevalence of GERD (39.3% vs 24.1%, P Descriptors Links Book Title Database Publisher Data Source Authors Kidambi,T., Toto,E., Ho,N., Taft,T., Hirano,I. Original/Translated Title URL Date of Electronic PMCID PMC3436048 Editors
Temporal trends of esophageal disorders by age in the Cerner Health Facts database	2016	Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD. Electronic address: jessica.petrick@nih.gov.; Division of Gastroenterology, Department of Medicine, Hepatology and Nutrit	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Annals of Epidemiology Periodical, Abbrev. Ann.Epidemiol. Pub Date Free Form Feb Volume 26 Issue 2 Start Page 151 Other Pages 4.e1-4 Notes LR: 20160426; CI: Published by Elsevier Inc.; GR: T32 DK007150/DK/NIDDK NIH HHS/United States; GR: T32DK007150/DK/NIDDK NIH HHS/United States; GR: UL1 TR000050/TR/NCATS NIH HHS/United States; GR: UL1TR00005/TR/NCATS NIH HHS/United States; GR: ZIA CP010220 Place of Publication United States ISSN/ISBN 1873-2585; 1047-2797 Accession Number PMID: 26762962 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; IM DOI 10.1016/j.annepidem.2015.11.004 [doi] Output Language Unknown(0) PMID 26762962 Abstract PURPOSE: Esophageal adenocarcinoma incidence has increased approximately 600% over the last 4 decades in the United States. Little research has been conducted on the temporal trends of gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE), yet it is important to establish whether these conditions have also increased with time or differ by age. METHODS: The Cerner Health Facts((R)) database contains information on 35 million patients between 2001 and 2010. GERD, BE, and esophageal cancer (EC) cases were defined using International Classification of Diseases, ninth edition codes. We calculated age-adjusted rates and 95% confidence intervals for GERD, BE, and EC. RESULTS: In this population, the overall, all-age rate per 100,000 encounters for GERD was 711.9, BE was 21.6, and EC was 6.1. During 2001-2010, GERD rates increased by approximately 50% and EC rates more than doubled, but BE rates declined by approximately 40%. Trends were similar by age, and all rates were higher in Caucasians and males. CONCLUSIONS: These data indirectly support the idea that increased incidence of EC may be partially due to GERD and raise the provocative hypothesis that BE rates may be decreasing possibly as a forerunner of continued stabilization of esophageal adenocarcinoma rates and a possible subsequent decline. Descriptors Links Book Title Database Publisher Data Source Authors Petrick,J.L., Nguyen,T., Cook,M.B. Original/Translated Title URL Date of Electronic 20151211 PMCID PMC4844025 Editors

E-mail