WTS database

Title	Pub Year	Author Sort descending	SearchLink
Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome	2013	Nicola de Bortoli, Irene Martinucci, Massimo Bellini, Santino Marchi, Division of Gastroenterology, University of Pisa, 56124 Pisa, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full World journal of gastroenterology Periodical, Abbrev. World J.Gastroenterol. Pub Date Free Form 21-Sep Volume 19 Issue 35 Start Page 5787 Other Pages 5797 Notes LR: 20151022; JID: 100883448; OID: NLM: PMC3793133; OTO: NOTNLM; 2012/09/24 [received]; 2012/11/14 [revised]; 2012/12/25 [accepted]; ppublish Place of Publication China ISSN/ISBN 2219-2840; 1007-9327 Accession Number PMID: 24124323 Language eng SubFile Journal Article; Review; IM DOI 10.3748/wjg.v19.i35.5787 [doi] Output Language Unknown(0) PMID 24124323 Abstract Several studies indicate a significant degree of overlap between irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). Likewise, both functional heartburn (FH) and IBS are functional digestive disorders that may occur in the same patients. However, data establishing a solid link between FH and IBS are lacking, mainly because the clinical definition of FH has undergone substantial changes over the years. The available literature on the overlap between GERD or FH and IBS highlights considerable heterogeneity in terms of the criteria and diagnostic procedures used to assess heartburn and IBS. In particular, several epidemiological studies included patients with concomitant IBS and GERD without any attempt to distinguish FH (as defined by the Rome III criteria) from GERD via pathophysiological investigations. Independent of these critical issues, there is preliminary evidence supporting a significant degree of FH-IBS overlap. This underscores the need for studies based on updated diagnostic criteria and accurate pathophysiological classifications, particularly to distinguish FH from GERD. This distinction would represent an essential starting point to achieving a better understanding of pathophysiology in the subclasses of patients with GERD and FH and properly assessing the different degrees of overlap between IBS and the subcategories of heartburn.The present review article intends to appraise and critically discuss current evidence supporting a possible concomitance of GERD or FH with IBS in the same patients and to highlight the pathophysiological relationships between these disorders. Descriptors Links Book Title Database Publisher Data Source Authors de Bortoli,N., Martinucci,I., Bellini,M., Savarino,E., Savarino,V., Blandizzi,C., Marchi,S. Original/Translated Title URL Date of Electronic PMCID PMC3793133 Editors
Nicotine patch therapy for smoking cessation combined with physician advice and nurse follow-up. One-year outcome and percentage of nicotine replacement	1994	Nicotine Dependence Center, Mayo Clinic, Rochester, MN 55905.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Jama Periodical, Abbrev. JAMA Pub Date Free Form 23-Feb Volume 271 Issue 8 Start Page 595 Other Pages 600 Notes LR: 20151119; JID: 7501160; 6M3C89ZY6R (Nicotine); 7U1EE4V452 (Carbon Monoxide); K5161X06LL (Cotinine); CIN: JAMA. 1994 Jul 6;272(1):32. PMID: 8007075; ppublish Place of Publication UNITED STATES ISSN/ISBN 0098-7484; 0098-7484 Accession Number PMID: 8301791 Language eng SubFile Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; AIM; IM DOI Output Language Unknown(0) PMID 8301791 Abstract OBJECTIVE: To determine the efficacy of a 22-mg nicotine patch combined with the National Cancer Institute program for physician advice and nurse follow-up in providing withdrawal symptom relief, 1-year smoking cessation outcome, and percentage of nicotine replacement. DESIGN: Randomized, double-blind, placebo-controlled trial. SUBJECTS: Two-hundred forty healthy volunteers who were smoking at least 20 cigarettes per day. INTERVENTIONS: Based on the National Cancer Institute program, subjects received smoking cessation advice from a physician. Follow-up and relapse prevention were provided by a study nurse during individual counseling sessions. Subjects were randomly assigned to 8 weeks of a 22-mg nicotine or placebo patch. MAIN OUTCOME MEASURES: Abstinence from smoking was verified by expired air carbon monoxide levels. Withdrawal symptoms were recorded during patch therapy, and the percentage of nicotine replacement was calculated by dividing serum nicotine and cotinine levels at week 8 of patch therapy by levels obtained while smoking. RESULTS: Higher smoking cessation rates were observed in the active nicotine patch group at 8 weeks (46.7% vs 20%) (P < .001) and at 1 year (27.5% vs 14.2%) (P = .011). Higher smoking cessation rates were also observed in subjects assigned to the active patch who had lower serum levels of nicotine and cotinine at baseline, and withdrawal symptom relief was better in the active patch group compared with placebo. CONCLUSIONS: Clinically significant smoking cessation can be achieved using nicotine patch therapy combined with physician intervention, nurse counseling, follow-up, and relapse prevention. Smokers with lower baseline nicotine and cotinine levels had better cessation rates, which provides indirect evidence that they had more adequate nicotine replacement with this fixed dose of transdermal nicotine than those smokers with higher baseline levels. Descriptors Administration, Cutaneous, Adult, Aged, Breath Tests, Carbon Monoxide/analysis, Cotinine/blood, Counseling/methods, Double-Blind Method, Female, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Nicotine/administration & dosage/adverse effects/blood, Nurses, Physician's Role, Smoking/therapy, Smoking Cessation/methods/statistics & numerical data, Substance Withdrawal Syndrome/therapy, Treatment Outcome Links Book Title Database Publisher Data Source Authors Hurt,R. D., Dale,L. C., Fredrickson,P. A., Caldwell,C. C., Lee,G. A., Offord,K. P., Lauger,G. G., Marusic,Z., Neese,L. W., Lundberg,T. G. Original/Translated Title URL Date of Electronic PMCID Editors
Puffing behavior during the smoking of a single cigarette in tobacco-dependent adolescents	2010	Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Boulevard, Baltimore, MD 21224, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Periodical, Abbrev. Nicotine Tob.Res. Pub Date Free Form Feb Volume 12 Issue 2 Start Page 164 Other Pages 167 Notes LR: 20151119; GR: Intramural NIH HHS/United States; JID: 9815751; 0 (Smoke); 6M3C89ZY6R (Nicotine); K5161X06LL (Cotinine); OID: NLM: PMC2816192; 2009/12/07 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-994X; 1462-2203 Accession Number PMID: 19969556 Language eng SubFile Journal Article; Research Support, N.I.H., Intramural; IM DOI 10.1093/ntr/ntp176 [doi] Output Language Unknown(0) PMID 19969556 Abstract INTRODUCTION: Adult and adolescent smokers regulate their nicotine and smoke intake by smoking low-yield cigarettes more intensely than high-yield cigarettes. One likely mechanism of nicotine regulation is altered puffing topography, which has been demonstrated in adult smokers. The purpose of this study was to examine the pattern of puffing behavior during the smoking of a single cigarette in adolescents. METHODS: Tobacco-dependent adolescents (n = 89) were enrolled in a treatment trial testing the efficacy of nicotine replacement therapy. About 1 week before their quit date, participants smoked ad libitum one of their usual brand of cigarettes during a laboratory session. Smoking topography measures included puff volume, puff duration, puff velocity, and interpuff interval. RESULTS: Controlling for sex, race, and number of puffs, puff volume and puff duration decreased 12.8% and 24.5%, respectively, from the first 3 to the last 3 puffs. Puff velocity and interpuff interval increased 14.8% and 13.5%, respectively. Puff volume was positively correlated with puff duration and puff velocity, whereas puff duration and puff velocity were negatively correlated. However, none of the topography measures were correlated with smoking history variables. DISCUSSION: These results suggest that adolescent smokers, like adults, are able to regulate smoke and nicotine intake on a puff-by-puff basis, therefore indicating that this aspect of smoking control is acquired early in the tobacco-dependence process. Descriptors Adolescent, Adolescent Behavior/psychology, Behavior, Addictive/psychology, Cotinine/analysis, Female, Forced Expiratory Volume, Humans, Inhalation Exposure/analysis, Male, Nicotine/administration & dosage/analysis, Smoke/analysis, Smoking/metabolism/psychology, Tobacco/chemistry, Tobacco Use Disorder/metabolism/psychology Links Book Title Database Publisher Data Source Authors Collins,C. C., Epstein,D. H., Parzynski,C. S., Zimmerman,D., Moolchan,E. T., Heishman,S. J. Original/Translated Title URL Date of Electronic 20091207 PMCID PMC2816192 Editors
Concentrations of bisphenol a, bisphenol a diglycidyl ether, and their derivatives in canned foods in Japanese markets	2008	Nihon Waters KK, Katokichi Shin-Osaka Building, Osaka, Japan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of Agricultural and Food Chemistry Periodical, Abbrev. J.Agric.Food Chem. Pub Date Free Form 26-Mar Volume 56 Issue 6 Start Page 2041 Other Pages 2047 Notes LR: 20131121; JID: 0374755; 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (Phenols); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); MLT3645I99 (bisphenol A); 2008/02/20 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 0021-8561; 0021-8561 Accession Number PMID: 18284199 Language eng SubFile Journal Article; IM DOI 10.1021/jf073106n [doi] Output Language Unknown(0) PMID 18284199 Abstract Bisphenol A (BPA), bisphenol A diglycidyl ether (BADGE), and their derivatives in 38 canned foods sold in Japan were measured using high-performance liquid chromatography-mass spectrometry (LC-MS) and LC-tandem mass spectrometry (LC-MS/MS). BPA, BADGE, BADGE.2H 2O, BADGE.HCl.H2O, BADGE.HCl, and BADGE.2HCl were 0-235.4, 0-3.4, 0-247.2, 0.2-196.4, 0-3.0, and 0-25.7 ng/g, respectively, which did not exceed acceptable daily intake for BPA and specific migration limit for BADGEs. BADGE was degraded by 58, 100, 46, and 58% in water (pH 7), 0.01 N HCl (pH 2), 0.01 N NaCl (pH 6.8), and 0.01 N NaCl with acetic acid (pH 2.5), respectively, when it was allowed to stand at 120 degrees C for 30 min. The prominent derivatives formed were BADGE.2H 2O and BADGE.HCl.H2O, which was formed not only in BADGE with added HCl but also in that with NaCl. Acetic acid accelerated the formation of both BADGE.2H2O and BADGE.HCl.H2O in NaCl. No BPA was detected in any simulation samples started from BADGE. The results suggest that BPA and BADGE are independently leached into canned foods and that BADGE is easily changed to more stable compounds such as BADGE.2H2O and BADGE.HCl.H2O by sterilization. Descriptors Benzhydryl Compounds, Chromatography, High Pressure Liquid, Epoxy Compounds/analysis, Food Handling/methods, Food Packaging, Food Preservation, Hot Temperature, Japan, Mass Spectrometry, Phenols/analysis, Sterilization Links Book Title Database Publisher Data Source Authors Yonekubo,J., Hayakawa,K., Sajiki,J. Original/Translated Title URL Date of Electronic 20080220 PMCID Editors
A community based study about knowledge and practices regarding tobacco Consumption and passive smoking in Gadap Town, Karachi	2007	Nisar, N., Department of Community Medicine, Baqai Medical University, Karachi, Pakistan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of the Pakistan Medical Association Periodical, Abbrev. J.Pak.Med.Assoc. Pub Date Free Form / Volume 57 Issue 4 Start Page 186 Other Pages 188 Notes Place of Publication ISSN/ISBN 0030-9982 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objective: To determine the proportion of people consuming tobacco in various forms, level of knowledge and practices regarding various harmful effects of tobacco and passive smoking. Methods: A cross-sectional study was conducted at Ghulam Mohammad Jokhio Goth, a small semi urban community of Gadap Town Karachi, which comprises of a population approximate 2225. About 157 people were interviewed regarding their tobacco consumption practices through a semi structured pre-tested questionnaire from June to August 2005. There were 314 households in the community and every alternate household was selected with a random start. The study subject was selected among all the adult members of 18 years age and above present at the time of interview in the household by lottery method and the questionnaire was administerd to those who were resident of GM Goth after taking consent. Results: In our study 110 (70%) people were tobacco consumers, 47% were knowledgeable about hazards of smoking, 22% were aware about passive smoking, and 90% started consuming tobacco below 20 years of age. The most popular form of tobacco was pan 40%, cigarette 39% and hookah 19%. Eighty four percent were regular smokers. Only 13.6% took counseling, 26.3% tried to quit smoking but none of them succeeded. About 23.5% smokers suffered from cough and headache due to smoking. When age, sex, marital status, income of the household, education and knowledge about hazards of smoking was compared, age and knowledge showed significant association while other variables did not show any significant association. Conclusion: Our study concluded that high proportion of people including men and women consume tobacco. Most of them were unaware about tobacco consumption hazards, and passive smoking. Descriptors adult, article, smoking, coughing, female, headache, health education, health hazard, household, human, income, informed consent, interview, knowledge, male, marriage, Pakistan, passive smoking, questionnaire, randomization, urban population Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Nisar,N., Qadri,M. H., Fatima,K., Perveen,S. Original/Translated Title URL Date of Electronic PMCID Editors
Monitoring the lactic acid bacterial diversity during shochu fermentation by PCR-denaturing gradient gel electrophoresis	2005	Nodai Culture Collection Center, Department of Brewing, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya, Tokyo 156-8502, Japan. 60020001@nodai.ac.jp	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of bioscience and bioengineering Periodical, Abbrev. J.Biosci.Bioeng. Pub Date Free Form Mar Volume 99 Issue 3 Start Page 216 Other Pages 221 Notes LR: 20131121; JID: 100888800; 33X04XA5AT (Lactic Acid); 2004/09/15 [received]; 2004/11/29 [accepted]; ppublish Place of Publication Japan ISSN/ISBN 1389-1723; 1347-4421 Accession Number PMID: 16233780 Language eng SubFile Journal Article; IM DOI S1389-1723(05)70357-1 [pii] Output Language Unknown(0) PMID 16233780 Abstract The presence of lactic acid bacteria (LAB) during shochu fermentation was monitored by PCR-denaturing gradient gel electrophoresis (DGGE) and by bacteriological culturing. No LAB were detected from fermented mashes by PCR-DGGE using a universal bacterial PCR primer set. However, PCR-DGGE using a new primer specific for the 16S rDNA of Lactococcus, Streptococcus, Tetragenococcus, Enterococcus, and Vagococcus and two primers specific for the 16S rDNA of Lactobacillus, Pediococcus, Leuconostoc, and Weissella revealed that Enterococcus faecium, Lactobacillus casei, Lactobacillus fermentum, Lactobacillus nagelii, Lactobacillus plantarum, Lactococcus lactis, Leuconostoc citreum, Leuconostoc mesenteroides, and Weissella cibaria inhabited in shochu mashes. It was also found that the LAB community composition during shochu fermentation changed after the main ingredient and water were added during the fermentation process. Therefore, we confirmed that PCR-DGGE using all three primers specific for groups of LAB together was well suited to the study of the LAB diversity in shochu mashes. The results of DGGE profiles were similar to the results of bacteriological culturing. In conclusion, LAB are present during shochu fermentation but not dominant. Descriptors Bacteria, Aerobic/genetics/isolation & purification/metabolism, Colony Count, Microbial/methods, Comet Assay/methods, Lactic Acid/metabolism, Nucleic Acid Denaturation, Polymerase Chain Reaction/methods, Wine/microbiology Links Book Title Database Publisher Data Source Authors Endo,A., Okada,S. Original/Translated Title URL Date of Electronic PMCID Editors
Severe recurrent carbon monoxide poisoning caused by smoking	2015	Nodholmsvej 34, 4171 Glumso. daniel.rasmussen@live.dk.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Ugeskrift for laeger Periodical, Abbrev. Ugeskr.Laeger Pub Date Free Form 26-Jan Volume 177 Issue 2A Start Page 78 Other Pages 79 Notes JID: 0141730; ppublish Place of Publication Denmark ISSN/ISBN 1603-6824; 0041-5782 Accession Number PMID: 25612978 Language dan SubFile English Abstract; Journal Article; IM DOI V05130268 [pii] Output Language Unknown(0) PMID 25612978 Abstract Carbon monoxide (CO) is an odourless, colourless and toxic gas. Sources of CO include car exhaust, charcoal and tobacco smoke. CO binds to haemoglobin forming carboxyhaemoglobin (COHb). Heavy smokers have COHb levels up to 15%. There are reports of COHb levels of 24,2% caused by tobacco use and 28,7% after narghile smoking. A 54-year-old woman with schizophrenia was admitted at the intensive care unit with COHb levels as high as 35% caused by cigarillo smoking. She also presented with severe thiazide-induced hyponatriaemia and high haemoglobin levels. Descriptors Links Book Title Database Publisher Data Source Authors Rasmussen,D.B., Jacobsen,V.B. Original/Translated Title Svaer recidiverende kulilteforgiftning forarsaget af tobaksrygning URL Date of Electronic PMCID Editors
Linking Global Youth Tobacco Survey (GYTS) data to the WHO Framework Convention on Tobacco Control (FCTC): the case for Lebanon	2008	Non-Communicable Disease Program World Health Organization, Beirut Office Glass Building 4th Floor, Museum Square Beirut Lebanon. saadeg@leb.emro.who.int	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Preventive medicine Periodical, Abbrev. Prev.Med. Pub Date Free Form Sep Volume 47 Suppl 1 Issue Start Page S15 Other Pages 9 Notes JID: 0322116; 0 (Tobacco Smoke Pollution); 2008/02/14 [received]; 2008/05/28 [revised]; 2008/06/04 [accepted]; 2008/06/12 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1096-0260; 0091-7435 Accession Number PMID: 18590759 Language eng SubFile Journal Article; IM DOI 10.1016/j.ypmed.2008.06.003 [doi] Output Language Unknown(0) PMID 18590759 Abstract OBJECTIVES: The purpose of this paper is to use data collected in the 2001 and 2005 Lebanon Global Youth Tobacco Survey (GYTS) to monitor articles in the WHO Framework Convention on Tobacco Control (WHO FCTC). This information is necessary to enhance the capacity of the Ministry of Health and relevant organizations to design, implement, and evaluate tobacco control and prevention programs in Lebanon, especially among adolescents. METHODS: The GYTS is a school-based survey which uses a two-stage sample design to produce representative, independent, cross-sectional estimates. The GYTS was conducted in 2001 and 2005 in Lebanon to produce representative national estimates. Data in this report are limited to students aged 13-15 years. In total, 5035 students from 50 schools participated in 2001; and 3341 students from 50 schools participated in 2005. RESULTS: The data in this report show that, in 2005, 8.6% of the students currently smoked cigarettes, but 33.9% currently smoked narguileh. Half of current smokers wanted to stop smoking and 6 in 10 have tried to stop during the past year but have failed. In 2005, exposure to SHS at home (78.4%) and in public places (74.4%) was very high; while 85.2% thought smoking should be banned in public places. Nearly 9 in 10 students who usually buy their cigarettes in stores were not refused purchase because of their age. Overall, only half of the students in Lebanon reported that during the past school year they had been taught about the dangers of smoking. CONCLUSIONS: Data in this report can be used as baseline measures for future evaluation of the tobacco control programs implemented by the Ministry of Health with particular attention to youth. The key for the Lebanese parliament is to develop, endorse, implement and enforce these new tobacco control laws and use the data from GYTS to monitor progress toward achieving the goals of the WHO FCTC. One key component of tobacco control needs to be the monitoring of Narguileh use among youth, a new emergency. Descriptors Adolescent, Adolescent Behavior, Advertising as Topic, Female, Humans, Lebanon/epidemiology, Male, Population Surveillance, Prevalence, Sex Factors, Smoking/epidemiology/prevention & control, Smoking Cessation/psychology/statistics & numerical data, Substance-Related Disorders/epidemiology/prevention & control, Tobacco Smoke Pollution/legislation & jurisprudence/prevention & control/statistics & numerical data Links Book Title Database Publisher Data Source Authors Saade,G., Warren,C. W., Jones,N. R., Asma,S., Mokdad,A. Original/Translated Title URL Date of Electronic 20080612 PMCID Editors
Body mass index, smoking, and alcohol and risks of Barrett's esophagus and esophageal adenocarcinoma: a UK prospective cohort study	2014	Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, NR4 7UY, UK, max.yates@nnuh.nhs.uk.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Digestive diseases and sciences Periodical, Abbrev. Dig.Dis.Sci. Pub Date Free Form Jul Volume 59 Issue 7 Start Page 1552 Other Pages 1559 Notes LR: 20151119; GR: 14136/Cancer Research UK/United Kingdom; GR: C864/A14136/Cancer Research UK/United Kingdom; GR: G1000143/Medical Research Council/United Kingdom; JID: 7902782; Adenocarcinoma Of Esophagus; OID: NLM: PMC4067535; 2013/08/20 [received]; 201 Place of Publication United States ISSN/ISBN 1573-2568; 0163-2116 Accession Number PMID: 24500448 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; AIM; IM DOI 10.1007/s10620-013-3024-z [doi] Output Language Unknown(0) PMID 24500448 Abstract BACKGROUND: The timing of the risk factors cigarette smoking, alcohol and obesity in the development of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) is unclear. AIMS: To investigate these exposures in the aetiology of BE and EAC in the same population. METHODS: The cohort included 24,068 men and women, aged 39-79 years, recruited between 1993 and 1997 into the prospective EPIC-Norfolk Study who provided information on anthropometry, smoking and alcohol intake. The cohort was monitored until December 2008 and incident cases identified. RESULTS: One hundred and four participants were diagnosed with BE and 66 with EAC. A body mass index (BMI) above 23 kg/m(2) was associated with a greater risk of BE [BMI >/=23 vs. 18.5 to 23 kg/m(2)). Neither smoking nor alcohol intake were associated with risk for BE. For EAC, all BMI categories were associated with risk, although statistically significant for only the highest (BMI >35 vs. BMI 18.5 to 23 kg/m(2)). There was an inverse association with >/=7 units alcohol/week (HR 0.51, 95 % CI 0.29-0.88) and with wine (HR 0.49, 95 % CI 0.23-1.04, p = 0.06, drinkers vs. non-drinkers). CONCLUSIONS: Obesity may be involved early in carcinogenesis and the association with EAC and wine should be explored. The data have implications for aetiological investigations and prevention strategies. Descriptors Links Book Title Database Publisher Data Source Authors Yates,M., Cheong,E., Luben,R., Igali,L., Fitzgerald,R., Khaw,K.T., Hart,A. Original/Translated Title URL Date of Electronic 20140206 PMCID PMC4067535 Editors
Multiple tobacco product use among US adolescents and young adults	2016	Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.; Norris Cotton Cancer Center,	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Mar Volume 25 Issue 2 Start Page 174 Other Pages 180 Notes LR: 20160301; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/; GR: CA077026/CA/NCI NIH HHS/United States; Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 25361744 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; IM DOI 10.1136/tobaccocontrol-2014-051638 [doi] Output Language Unknown(0) PMID 25361744 Abstract OBJECTIVE: To assess the extent to which multiple tobacco product use among adolescents and young adults falls outside current Food and Drug Administration (FDA) regulatory authority. METHODS: We conducted a web-based survey of 1596 16-26-year-olds to assess use of 11 types of tobacco products. We ascertained current (past 30 days) tobacco product use among 927 respondents who ever used tobacco. Combustible tobacco products included cigarettes, cigars (little filtered, cigarillos, premium) and hookah; non-combustible tobacco products included chew, dip, dissolvables, e-cigarettes, snuff and snus. We then fitted an ordinal logistic regression model to assess demographic and behavioural associations with higher levels of current tobacco product use (single, dual and multiple product use). RESULTS: Among 448 current tobacco users, 54% were single product users, 25% dual users and 21% multiple users. The largest single use category was cigarettes (49%), followed by hookah (23%), little filtered cigars (17%) and e-cigarettes (5%). Most dual and multiple product users smoked cigarettes, along with little filtered cigars, hookah and e-cigarettes. Forty-six per cent of current single, 84% of dual and 85% of multiple tobacco product users consumed a tobacco product outside FDA regulatory authority. In multivariable analysis, the adjusted risk of multiple tobacco use was higher for males, first use of a non-combustible tobacco product, high sensation seeking respondents and declined for each additional year of age that tobacco initiation was delayed. CONCLUSIONS: Nearly half of current adolescent and young adult tobacco users in this study engaged in dual and multiple tobacco product use; the majority of them used products that fall outside current FDA regulatory authority. This study supports FDA deeming of these products and their incorporation into the national media campaign to address youth tobacco use. Descriptors Links Book Title Database Publisher Data Source Authors Soneji,S., Sargent,J., Tanski,S. Original/Translated Title URL Date of Electronic 20141031 PMCID PMC4547881 Editors

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