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Waterpipe (shisha) smoking among adolescents in Germany: Results of the KiGGS study: first follow-up (KiGGS Wave 1) 2015 Abteilung fur Epidemiologie und Gesundheitsmonitoring, Robert Koch-Institut, General-Pape-Str. 62-66, 12101, Berlin, Deutschland, b.kuntz@rki.de.
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Print(0)
Ref Type
Journal Article
Periodical, Full
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Periodical, Abbrev.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Pub Date Free Form
Apr
Volume
58
Issue
5-Apr
Start Page
467
Other Pages
473
Notes
LR: 20160707; JID: 101181368; ppublish
Place of Publication
Germany
ISSN/ISBN
1437-1588; 1436-9990
Accession Number
PMID: 25665891
Language
ger
SubFile
English Abstract; Journal Article; IM
DOI
10.1007/s00103-015-2128-3 [doi]
Output Language
Unknown(0)
PMID
25665891
Abstract
BACKGROUND: At the beginning of the 21st century, waterpipe (shisha) smoking has become a new and global youth trend in tobacco consumption. Despite the fact that this type of tobacco use can also lead to serious health problems, there are only a few studies on this topic in Germany. OBJECTIVES: The aim of this study was to determine the prevalence of waterpipe smoking among 12- to 17-year-old adolescents. Age- and sex-related differences were analyzed and, for the first time in Germany, the association between parental socioeconomic status and waterpipe use was examined. MATERIALS AND METHODS: Data were obtained from the first follow-up of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 1), which was conducted from 2009 to 2012. Waterpipe smoking was assessed among adolescents aged 12 to 17 years using three items (n = 4,543). We calculated prevalence rates and age-adjusted odds ratios (OR) with 95 % confidence intervals (95 % CI). RESULTS: Lifetime prevalence of waterpipe use was 28.9 % (95 % CI: 26.9-31.0). Approximately one fifth (20.6 %; 95 % CI: 18.8-22.6) of the adolescents reported waterpipe use in the past 12 months, one tenth (10.0 %; 95 % CI: 8.6-11.6) reported current use (at least once during the past 30 days). In both sexes, prevalence increased with age. Waterpipe smoking rates were significantly higher among boys than girls, while no significant differences were found regarding parental socioeconomic status. CONCLUSIONS: A considerable number of adolescents in Germany are at least occasional waterpipe (shisha) smokers. Because of waterpipe related health and addiction risks that are often underestimated by adolescents, specific health education and prevention measures are necessary.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Kuntz,B., Lampert,T., KiGGS Study Group
Original/Translated Title
Wasserpfeifenkonsum (Shisha-Rauchen) bei Jugendlichen in Deutschland : Ergebnisse der KiGGS-Studie - Erste Folgebefragung (KiGGS Welle 1)
URL
Date of Electronic
PMCID
Editors
Risk factors on the development of new-onset gastroesophageal reflux symptoms. A population-based prospective cohort study: the HUNT study 2015 1] Institute of Clinical Research, University of Southern Denmark, Odense, Denmark [2] Department of Medical Gastroenterology S, Odense University Hospital, Odense, Denmark [3] Medical Department, Levanger Hospital, Nord-Trondelag Hospital Trust, Levanger
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The American Journal of Gastroenterology
Periodical, Abbrev.
Am.J.Gastroenterol.
Pub Date Free Form
Mar
Volume
110
Issue
3
Start Page
393
Other Pages
400; quiz 401
Notes
JID: 0421030; 2014/09/01 [received]; 2014/12/02 [revised]; 2015/01/07 [accepted]; 2015/02/10 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1572-0241; 0002-9270
Accession Number
PMID: 25665934
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1038/ajg.2015.18 [doi]
Output Language
Unknown(0)
PMID
25665934
Abstract
OBJECTIVES: Gastroesophageal reflux disease (GERD) is a highly prevalent disorder. This study assessed the risk factors of new-onset gastroesophageal reflux symptoms (GERS). METHODS: The study was based on the HUNT study, a prospective population-based cohort study conducted in 1995-1997 and 2006-2009 in Nord-Trondelag County, Norway. All inhabitants from 20 years of age were invited. Risk factors of new-onset heartburn or acid regurgitation were examined using logistic regression, providing odds ratios (OR) and 95% confidence intervals (CI). RESULTS: A total of 29,610 individuals were included (61% response rate). Participants reporting no GERS at baseline and severe GERS at follow-up (new-onset GERS; n=510) were compared with participants reporting no complaints at both times (n=14,406). Increasing age (OR 1.01 per year, 95% CI 1.00-1.02) was positively associated, whereas male sex (OR 0.81, 95% CI 0.66-0.98) and higher education (OR 0.69, 95% CI 0.56-0.86) were negatively associated with new-onset GERS. Gain in body mass index (BMI) was dose-dependently associated with new-onset GERS (OR 1.30 per unit increase in BMI, 95% CI 1.25-1.35), irrespective of baseline BMI. Previous and current tobacco smoking were associated with new-onset GERS (OR 1.37, 95% CI 1.07-1.76 and OR 1.29, 95% CI 1.00-1.67, respectively). Tobacco smoking cessation was associated with new-onset GERS among those with gain in BMI upon quitting (OR 2.03, 95% CI 1.31-3.16, with >3.5 BMI units increase). CONCLUSIONS: New-onset GERS were associated with increasing age, female sex, lower education, gain in BMI, and ever tobacco smoking. Tobacco smoking cessation was associated with new-onset GERS among those who gained weight upon quitting.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Hallan,A., Bomme,M., Hveem,K., Moller-Hansen,J., Ness-Jensen,E.
Original/Translated Title
URL
Date of Electronic
20150210
PMCID
Editors
Risky behaviors, e-cigarette use and susceptibility of use among college students 2015 University at Buffalo, State University of New York, School of Public Health and Health Professions, Department of Community Health and Health Behavior, Buffalo, NY, USA. Electronic address: mls38@buffalo.edu.; University at Buffalo, State University of N
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Drug and alcohol dependence
Periodical, Abbrev.
Drug Alcohol Depend.
Pub Date Free Form
1-Apr
Volume
149
Issue
Start Page
25
Other Pages
30
Notes
CI: Copyright (c) 2015; JID: 7513587; OTO: NOTNLM; 2014/09/11 [received]; 2014/12/11 [revised]; 2015/01/02 [accepted]; 2015/01/24 [aheadofprint]; ppublish
Place of Publication
Ireland
ISSN/ISBN
1879-0046; 0376-8716
Accession Number
PMID: 25666362
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.drugalcdep.2015.01.001 [doi]
Output Language
Unknown(0)
PMID
25666362
Abstract
BACKGROUND: Since 2007, there has been a rise in the use of electronic cigarettes (e-cigarettes). The present study uses cross-sectional data (2013) to examine prevalence, correlates and susceptibility to e-cigarettes among young adults. METHODS: Data were collected using an Internet survey from a convenience sample of 1437, 18-23 year olds attending four colleges/universities in Upstate New York. Results were summarized using descriptive statistics; logistic regression models were analyzed to identify correlates of e-cigarette use and susceptibility to using e-cigarettes. RESULTS: Nearly all respondents (95.5%) reported awareness of e-cigarettes; 29.9% were ever users and 14.9% were current users. Younger students, males, non-Hispanic Whites, respondents reporting average/below average school ability, ever smokers and experimenters of tobacco cigarettes, and those with lower perceptions of harm regarding e-cigarettes demonstrated higher odds of ever use or current use. Risky behaviors (i.e., tobacco, marijuana or alcohol use) were associated with using e-cigarettes. Among never e-cigarette users, individuals involved in risky behaviors or, with lower harm perceptions for e-cigarettes, were more susceptible to future e-cigarette use. CONCLUSIONS: More e-cigarette users report use of another nicotine product besides e-cigarettes as the first nicotine product used; this should be considered when examining whether e-cigarette use is related to cigarette susceptibility. Involvement in risky behaviors is related to e-cigarette use and susceptibility to e-cigarette use. Among college students, e-cigarette use is more likely to occur in those who have also used other tobacco products, marijuana, and/or alcohol.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ireland Ltd
Data Source
Authors
Saddleson,M.L., Kozlowski,L.T., Giovino,G.A., Hawk,L.W., Murphy,J.M., MacLean,M.G., Goniewicz,M.L., Homish,G.G., Wrotniak,B.H., Mahoney,M.C.
Original/Translated Title
URL
Date of Electronic
20150124
PMCID
Editors
Toxicant content, physical properties and biological activity of waterpipe tobacco smoke and its tobacco-free alternatives 2015 Department of Mechanical Engineering, American University of Beirut, Beirut, Lebanon Department of Psychology, Center for the Study of Tobacco Products, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Safety of Pesticides, German
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Mar
Volume
24 Suppl 1
Issue
Start Page
i22
Other Pages
i30
Notes
LR: 20150319; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: P50DA036105/DA/NIDA NIH HHS/United States; GR: R0
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 25666550
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Review; IM
DOI
10.1136/tobaccocontrol-2014-051907 [doi]
Output Language
Unknown(0)
PMID
25666550
Abstract
OBJECTIVES: Waterpipe smoking using sweetened, flavoured tobacco products has become a widespread global phenomenon. In this paper, we review chemical, physical and biological properties of waterpipe smoke. DATA SOURCES: Peer-reviewed publications indexed in major databases between 1991 and 2014. Search keywords included a combination of: waterpipe, narghile, hookah, shisha along with names of chemical compounds and classes of compounds, in addition to terms commonly used in cellular biology and aerosol sizing. STUDY SELECTION: The search was limited to articles published in English which reported novel data on waterpipe tobacco smoke (WTS) toxicant content, biological activity or particle size and which met various criteria for analytical rigour including: method specificity and selectivity, precision, accuracy and recovery, linearity, range, and stability. DATA EXTRACTION: Multiple researchers reviewed the reports and collectively agreed on which data were pertinent for inclusion. DATA SYNTHESIS: Waterpipe smoke contains significant concentrations of toxicants thought to cause dependence, heart disease, lung disease and cancer in cigarette smokers, and includes 27 known or suspected carcinogens. Waterpipe smoke is a respirable aerosol that induces cellular responses associated with pulmonary and arterial diseases. Except nicotine, smoke generated using tobacco-free preparations marketed for 'health conscious' users contains the same or greater doses of toxicants, with the same cellular effects as conventional products. Toxicant yield data from the analytical laboratory are consistent with studies of exposure biomarkers in waterpipe users. CONCLUSIONS: A sufficient evidence base exists to support public health interventions that highlight the fact that WTS presents a serious inhalation hazard.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Shihadeh,A., Schubert,J., Klaiany,J., El Sabban,M., Luch,A., Saliba,N.A.
Original/Translated Title
URL
Date of Electronic
20150209
PMCID
PMC4345918
Editors
Long-term prognostic effect of coronary atherosclerotic burden: validation of the computed tomography-Leaman score 2015 From the Centro Cardiologico Monzino, IRCCS, Milan, Italy (S.M., G.P., A.L.B., E.B., M.P., D.A.); Cardiology Department, Hospital de Santa Cruz, CHLO, Lisbon, Portugal (P.D.A.G.); Cardiovascular Center, Hospital da Luz, ESS, Lisbon, Portugal (P.D.A.G.); C
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Circulation.Cardiovascular imaging
Periodical, Abbrev.
Circ.Cardiovasc.Imaging
Pub Date Free Form
Feb
Volume
8
Issue
2
Start Page
e002332
Other Pages
Notes
CI: (c) 2014; JID: 101479935; CIN: Circ Cardiovasc Imaging. 2015 Feb;8(2):e003081. PMID: 25666718; OTO: NOTNLM; ppublish
Place of Publication
United States
ISSN/ISBN
1942-0080; 1941-9651
Accession Number
PMID: 25666717
Language
eng
SubFile
Journal Article; Validation Studies; IM
DOI
10.1161/CIRCIMAGING.114.002332 [doi]
Output Language
Unknown(0)
PMID
25666717
Abstract
BACKGROUND: Computed tomography-adapted Leaman score (CT-LeSc) was developed to quantify coronary CT angiography information about atherosclerotic burden (lesion localization, stenosis degree, and plaque composition). The objective of the study is to evaluate CT-LeSc long-term prognostic value in patients with suspected coronary artery disease (CAD). METHODS AND RESULTS: Single-center prospective registry including 1304 consecutive patients undergoing coronary CT angiography for suspected CAD. High CT-LeSc was defined by upper tertile (score, >5) cutoff. Segment involvement score and segment stenosis score were also evaluated. Hard cardiac events (cardiac death and nonfatal acute coronary syndromes) were considered for analysis. Different Cox regression models were used to identify independent event predictors. Kaplan-Meier event-free survival was evaluated in 4 patient subgroups stratified by obstructive (>/=50% stenosis) versus nonobstructive CAD and a high (>5) versus a low (=5) CT-LeSc. Of 1196 patients included in the final analysis (mean follow-up of 52+/-22 months), 125 patients experienced 136 hard events (18 cardiac deaths and 118 nonfatal myocardial infarction). All atherosclerotic burden scores were independent predictors of cardiac events (hazard ratios of 3.09 for segment involvement score, 4.42 for segment stenosis score, and 5.39 for CT-LeSc). Cumulative event-free survival was 76.8% with a high CT-LeSc and 96.0% with a low CT-LeSc. Event-free survival in nonobstructive CAD with high CT-LeSc (78.6%) was similar to obstructive CAD with high CT-LeSc (76.5%) but lower than obstructive CAD with low CT-LeSc (80.7%). CONCLUSIONS: CT-LeSc is an independent long-term predictor of hard cardiac events. Patients with nonobstructive CAD and high CT-LeSc had hard event-free survival similar to patients with obstructive CAD.
Descriptors
Links
Book Title
Database
Publisher
American Heart Association, Inc
Data Source
Authors
Mushtaq,S., De Araujo Goncalves,P., Garcia-Garcia,H.M., Pontone,G., Bartorelli,A.L., Bertella,E., Campos,C.M., Pepi,M., Serruys,P.W., Andreini,D.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Correlation between nicotine dependence and barriers to cessation between exclusive cigarette smokers and dual (water pipe) smokers among Arab Americans 2015 Department of Social and Behavioral Health, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.; College of Nursing, University of Florida, Gainesville, FL, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Substance abuse and rehabilitation
Periodical, Abbrev.
Subst.Abuse Rehabil.
Pub Date Free Form
30-Jan
Volume
6
Issue
Start Page
25
Other Pages
32
Notes
LR: 20150214; JID: 101558476; OID: NLM: PMC4321602; OTO: NOTNLM; 2015 [ecollection]; 2015/01/30 [epublish]; epublish
Place of Publication
New Zealand
ISSN/ISBN
1179-8467; 1179-8467
Accession Number
PMID: 25674035
Language
eng
SubFile
Journal Article
DOI
10.2147/SAR.S72360 [doi]
Output Language
Unknown(0)
PMID
25674035
Abstract
BACKGROUND: Evidence suggests that dual cigarette and water pipe use is growing among minority groups, particularly among Arab Americans. Differences in nicotine dependence and barriers to smoking cessation among such dual smokers have not been previously examined in this population. We examined potential differences that might exist between exclusive cigarette smokers and dual smokers (cigarette and water pipe) pertaining to nicotine dependence and barriers to cessation among Arab Americans. METHODS: We conducted a cross-sectional study using a convenience sample of self-identified Arab immigrant smokers (n=131) living in the Richmond, VA metropolitan area. Data were collected using four questionnaires: Demographic and Cultural Information questionnaire, Tobacco Use questionnaire, Fagerstrom Test for Nicotine Dependence (FTND) questionnaire, and Barriers to Cessation questionnaire. We examined differences in nicotine dependence and barriers to cessation between exclusive cigarette smokers and dual smokers of cigarettes and water pipe. Furthermore, we explored the correlations of these measures with select variables. RESULTS: There was a significant difference in the FTND scores between the exclusive cigarette smokers (mean M=2.55, standard deviation [SD] =2.10) and dual smokers (M=3.71, SD =2.42); t(129) = (2.51), P=0.0066. There was also a significant difference in the Barriers to Cessation scores between exclusive cigarette smokers (M=38.47, SD =13.07) and dual smokers (M=45.21, SD =9.27); t(129) = (2.56), P=0.0058. Furthermore, there was a highly significant correlation among FTND scores, Barriers to Cessation scores, and past quit attempts among dual smokers. CONCLUSION: Water pipe tobacco smoking seems to be both adding to the dependence potential of cigarette smoking and enhancing barriers to cessation in our study sample. However, the high correlation between quit attempts, FTND, and barriers to cessation needs further investigation to ascertain the possible reasons behind it. This preliminary study utilized a cross-sectional survey among participants of a rather small convenience sample, especially in the dual smokers group. Thus, there is a need to examine these differences via a longitudinal design in a larger sample.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
El-Shahawy,O., Haddad,L.
Original/Translated Title
URL
Date of Electronic
20150130
PMCID
PMC4321602
Editors
Use of group quarantine in Ebola control - Nigeria, 2014 2015
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
MMWR.Morbidity and mortality weekly report
Periodical, Abbrev.
MMWR Morb.Mortal.Wkly.Rep.
Pub Date Free Form
13-Feb
Volume
64
Issue
5
Start Page
124
Other Pages
Notes
JID: 7802429; ppublish
Place of Publication
United States
ISSN/ISBN
1545-861X; 0149-2195
Accession Number
PMID: 25674994
Language
eng
SubFile
Journal Article; IM
DOI
mm6405a3 [pii]
Output Language
Unknown(0)
PMID
25674994
Abstract
On July 20, 2014, the first known case of Ebola virus disease (Ebola) in Nigeria, in a traveler from Liberia, led to an outbreak that was successfully curtailed with infection control, contact tracing, isolation, and quarantine measures coordinated through an incident management system. During this outbreak, most contacts underwent home monitoring, which included instructions to stay home or to avoid crowded areas if staying home was not possible. However, for five contacts with high-risk exposures, group quarantine in an observation unit was preferred because the five had crowded home environments or occupations that could have resulted in a large number of community exposures if they developed Ebola.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Grigg,C., Waziri,N.E., Olayinka,A.T., Vertefeuille,J.F., Centers for Disease Control and Prevention (CDC)
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Endemicity of Legionella pneumophila serogroup 3 in a hospital water supply 1989 Infectious Diseases Department, University of Turin, Italy.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of hospital infection
Periodical, Abbrev.
J.Hosp.Infect.
Pub Date Free Form
Apr
Volume
13
Issue
3
Start Page
281
Other Pages
288
Notes
LR: 20121115; JID: 8007166; ppublish
Place of Publication
ENGLAND
ISSN/ISBN
0195-6701; 0195-6701
Accession Number
PMID: 2567758
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
Output Language
Unknown(0)
PMID
2567758
Abstract
A microbiological and epidemiological investigation at the Infectious Diseases Hospital in Turin, Italy, demonstrated Legionella pneumophila serogroup 3 at 10(2) to greater than 4 X 10(3) cfu l-1 from 24 of 32 hot water samples collected from hand-basins in six separate buildings. A sample taken from the public water supply, and a hot water sample (80 degrees C) collected from hot water tanks, did not yield legionellas. Legionella pneumophila serogroup 3 was found in samples taken at the first point of mixed hot and cold water (50 degrees C) at 3 X 10(2) cfu l-1. 12 of 26 samples from the shower-heads yielded 10(3) to 2.5 X 10(5) cfu l-1 and one of 12 water samples from oxygen bubble humidifiers tested yielded 1.6 X 10(4) cfu l-1. No other legionellas species or serogroups of Legionella pneumophila were isolated during the study. No cases of nosocomial pneumonia were detected among 3653 patients' records, nor was there serological evidence of Legionella infection in the 180 patients tested.
Descriptors
Environmental Monitoring, Epidemiological Monitoring, Female, Hospitals, Humans, Italy, Legionella/isolation & purification, Legionnaires' Disease/epidemiology, Male, Prospective Studies, Retrospective Studies, Sanitary Engineering, Water Microbiology, Water Supply/standards
Links
Book Title
Database
Publisher
Data Source
Authors
Franzin,L., Castellani Pastoris,M., Gioannini,P., Villani,G.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Water pipe smoking and dermatologic consequences 2015 Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of the European Academy of Dermatology and Venereology : JEADV
Periodical, Abbrev.
J.Eur.Acad.Dermatol.Venereol.
Pub Date Free Form
Aug
Volume
29
Issue
8
Start Page
1481
Other Pages
1484
Notes
CI: (c) 2015; JID: 9216037; 2014/11/21 [received]; 2014/12/24 [accepted]; 2015/02/10 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1468-3083; 0926-9959
Accession Number
PMID: 25677592
Language
eng
SubFile
Journal Article; Review; IM
DOI
10.1111/jdv.12984 [doi]
Output Language
Unknown(0)
PMID
25677592
Abstract
Water pipe smoking is a recently growing addiction worldwide. It has become popular in Africa and the Western World and enfaces a renaissance in Middle East and Asia. The smoking technique leads to a different exposure to potential hazardous compounds compared to cigarette or classical pipe smoking. The common assumption that water pipe smoking is less dangerous to health is not substantiated by scientific data. Non-tobacco-based preparations reduce the exposure to nicotine but may contain equal or even higher concentrations of other toxic compounds. The medical literature on adverse effect of water pipe smoking on skin and oral mucosa is reviewed but future research is a demand.
Descriptors
Links
Book Title
Database
Publisher
European Academy of Dermatology and Venereology
Data Source
Authors
Wollina,U.
Original/Translated Title
URL
Date of Electronic
20150210
PMCID
Editors
Widespread occurrence and accumulation of bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives in human blood and adipose fat 2015 Tianjin Key Laboratory of Environmental Remediation and Pollution Control/Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, Nankai University , Tianjin 300071, China.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Environmental science & technology
Periodical, Abbrev.
Environ.Sci.Technol.
Pub Date Free Form
3-Mar
Volume
49
Issue
5
Start Page
3150
Other Pages
3157
Notes
GR: 1U38EH000464-01/EH/NCEH CDC HHS/United States; JID: 0213155; 0 (Benzhydryl Compounds); 0 (Epoxy Compounds); 0 (bisphenol F diglycidyl ether); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); 2015/02/20 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1520-5851; 0013-936X
Accession Number
PMID: 25679329
Language
eng
SubFile
Journal Article; Research Support, U.S. Gov't, P.H.S.; IM
DOI
10.1021/acs.est.5b00096 [doi]
Output Language
Unknown(0)
PMID
25679329
Abstract
Despite the widespread use of bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) in various consumer products, studies on human exposure to these compounds are scarce. In this study, BADGE, BFDGE, and seven of their derivatives were determined in human adipose fat and blood plasma samples collected from New York City, NY. Bisphenol A bis (2,3-dihydroxypropyl) ether [BADGE.2H2O] was the major BADGE derivative found in 60% of the adipose samples and 70% of the plasma samples analyzed. High concentrations and detection frequencies of BFDGE were found in both adipose and plasma samples. BFDGE concentrations in adipose fat ranged from 19.1 to 4500 ng/g wet weight. A significant correlation between BADGE or BFDGE and their derivatives in adipose and plasma samples suggested hydration of these reactive compounds in humans. A significant positive correlation existed between BADGEs (i.e., the sum of BADGE and its five derivatives) and BFDGEs in adipose samples, which suggested similar exposure sources and pathways for these compounds in humans. Bisphenol A (BPA) also was analyzed in adipose fat and plasma, and its concentrations were positively correlated with those of BADGEs, which confirmed coexposure of BADGEs and BPA in humans.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Wang,L., Xue,J., Kannan,K.
Original/Translated Title
URL
Date of Electronic
20150220
PMCID
Editors