WTS database

Title	Pub Year Sort descending	Author	SearchLink
Distribution and molecular characterization of genes encoding CTX-M and AmpC beta-lactamases in Escherichia coli isolated from an Indian urban aquatic environment	2015	Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110021, India.; Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Science of the total environment Periodical, Abbrev. Sci.Total Environ. Pub Date Free Form 1-Feb Volume 505 Issue Start Page 350 Other Pages 356 Notes CI: Copyright (c) 2014; JID: 0330500; 0 (Bacterial Proteins); EC 3.5.2.- (beta-lactamase CTX-M-15); EC 3.5.2.6 (AmpC beta-lactamases); EC 3.5.2.6 (beta-Lactamases); OTO: NOTNLM; 2014/06/16 [received]; 2014/08/14 [revised]; 2014/09/25 [accepted]; 2014/10/2 Place of Publication Netherlands ISSN/ISBN 1879-1026; 0048-9697 Accession Number PMID: 25461036 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.scitotenv.2014.09.084 [doi] Output Language Unknown(0) PMID 25461036 Abstract Aquatic environments harboring antibiotic resistant Escherichia coli constitute an important public health concern. Thus, it is important to characterize the resistance genetic elements of waterborne E. coli. It is also important to identify the predominant clonal groups/phylogroups represented by resistant strains to understand the epidemiology of antibiotic resistant E. coli in natural environments, and to identify the role of well-established genotypes in the spread of resistance in a particular geographical area through natural environments. In the present investigation, E. coli strains (n=126) isolated from various points along the river Yamuna traversing through the National Capital Territory of Delhi (India) were grouped phylogenetically. A collection of 61 strains representing all phylogroups was investigated for extended-spectrum beta-lactamase (ESBL) and AmpC production. blaTEM, blaSHV and blaCTX-M genes were detected and analyzed, promoter/attenuator mutations associated with chromosomally-mediated AmpC overexpression were identified, and plasmid-mediated ampC was determined. blaTEM was the most widespread (100%) gene followed by bla(CTX-M) (16%), and plasmid-mediated ampC (3%). bla(CTX-M-15) and bla(CMY-42) were identified as the genes encoding CTX-M type ESBL and CIT type AmpC beta-lactamases, respectively. CTX-M-15 ESBL phenotype was most common in phylogroup D (50%), followed by phylogroups B1 (30%), and A (20%). E. coli that produce plasmid-mediated AmpC were rare and present only in phylogroup D. Presence of multi beta-lactam resistance, bla(CTX-M-15) and bla(CMY-42) in waterborne E. coli belonging to virulence-associated phylogroup D highlights the need for routine surveillance of resistance determinants in aquatic environments. This is also the first report for the presence of bla(CMY-42) in waterborne E. coli. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Bajaj,P., Singh,N.S., Kanaujia,P.K., Virdi,J.S. Original/Translated Title URL Date of Electronic 20141029 PMCID Editors
Association Between Childhood Residential Mobility and Non-medical Use of Prescription Drugs Among American Youth	2015	Department of Epidemiology, Robert C. Byrd Health Sciences Center, West Virginia University School of Public Health, P.O. Box 9190, Morgantown, WV, 26506-9190, USA. mstabler@hsc.wvu.edu.; Department of Epidemiology, Injury Control Research Center, West Vi	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Maternal and child health journal Periodical, Abbrev. Matern.Child Health J. Pub Date Free Form Dec Volume 19 Issue 12 Start Page 2646 Other Pages 2653 Notes GR: R49CE002109/CE/NCIPC CDC HHS/United States; JID: 9715672; OTO: NOTNLM; ppublish Place of Publication United States ISSN/ISBN 1573-6628; 1092-7875 Accession Number PMID: 26156823 Language eng SubFile Journal Article; Research Support, U.S. Gov't, P.H.S.; IM DOI 10.1007/s10995-015-1785-z [doi] Output Language Unknown(0) PMID 26156823 Abstract INTRODUCTION: Prescription drug abuse is a public health epidemic, resulting in 15,000 deaths annually. Disruption of childhood residence has been shown to increase drug-seeking behavior among adolescents; however, little research has explored its association specifically with non-medical use of prescription drugs (NMUPD). The objective of the study was to measure the association between residential mobility and NMUPD. METHODS: The 2010 National Survey on Drug Use and Health data were analyzed for 15,745 participants aged 12-17 years. NMUPD was defined as self-report of any non-medical use (i.e., taking a prescription drug that was not prescribed to them or consumption for recreational purposes) of tranquilizers, pain relievers, sedatives, or stimulants. Logistic regression for survey data was used to estimate the association between residential mobility and NMUPD, adjusting for potential confounders. RESULTS: After controlling for demographic, intrapersonal, interpersonal, and community factors, adolescents with low mobility (1-2 moves in the past 5 years) and residential instability (>/=3 moves) were 16% (OR 1.16, 95% CI 1.01, 1.33) and 25% (OR 1.25, 95% CI 1.00, 1.56) more likely to report NMUPD compared to non-mobile adolescents (0 moves). Low-mobile adolescents were 18% (OR 1.18, 95% CI 1.01, 1.38) more likely to abuse pain relievers, specifically. No relationship was found between moving and tranquilizer, stimulant, or sedative use. DISCUSSION: Increasing childhood residential mobility is associated with NMUPD; therefore, efforts to prevent NMUPD should target mobile adolescents. Further examination of the psychological effects of moving and its association with pain reliever abuse is indicated. Descriptors Links Book Title Database Publisher Data Source Authors Stabler,M.E., Gurka,K.K., Lander,L.R. Original/Translated Title URL Date of Electronic PMCID Editors
Pre- and postnatal exposure to tobacco smoke and respiratory outcomes during the first year	2015	Unit of Addictive Disorders, San Marcelino Primary Health Care Center, Valencia, Spain; Center for Public Health Research (CSISP/FISABIO), Valencia, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Indoor air Periodical, Abbrev. Indoor Air Pub Date Free Form Feb Volume 25 Issue 1 Start Page 4 Other Pages 12 Notes CI: (c) 2014; JID: 9423515; 0 (Tobacco Smoke Pollution); OTO: NOTNLM; 2014/01/17 [received]; 2014/05/02 [accepted]; 2014/06/21 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1600-0668; 0905-6947 Accession Number PMID: 24810295 Language eng SubFile Journal Article; Multicenter Study; IM DOI 10.1111/ina.12128 [doi] Output Language Unknown(0) PMID 24810295 Abstract The different role of prenatal and postnatal exposure to tobacco smoke in respiratory outcomes in infants has not yet been clearly established. Our objective is to assess the effects of these exposures on the risk of respiratory outcomes during the first year of life of infants from a Spanish multicenter cohort study. A total of 2506 women were monitored until delivery. About 2039 infants made up the final population. The outcomes were caused by the occurrence of the following: otitis, cough persisting for more than 3 weeks, lower respiratory tract symptoms (wheezing or chestiness), and lower respiratory tract infections (bronchitis, bronchiolitis, or pneumonia). The relationship between prenatal and postnatal exposure and health outcomes was explored using logistic regression analysis. Maternal smoking during pregnancy increased the odds for wheezing (OR: 1.41, 95% CI: 0.99-2.01) and chestiness (OR: 1.46, 95% CI: 1.03-2.01). Postnatal exposure from fathers was associated with otitis (OR: 1.25, 95% CI: 1.01-1.54). Passive exposure at work of non-smoking mothers during pregnancy was related to cough (OR: 1.62, 95% CI: 1.05-2.51). Exposure to tobacco smoke was related to a higher risk of experiencing respiratory outcomes in young infants. Prenatal exposure was that most clearly associated with the respiratory outcomes analyzed. Descriptors Links Book Title Database Publisher John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Data Source Authors Fuentes-Leonarte,V., Estarlich,M., Ballester,F., Murcia,M., Esplugues,A., Aurrekoetxea,J.J., Basterrechea,M., Fernandez-Somoano,A., Morales,E., Gascon,M., Tardon,A., Rebagliato,M. Original/Translated Title URL Date of Electronic 20140621 PMCID Editors
Long-term prognostic effect of coronary atherosclerotic burden: validation of the computed tomography-Leaman score	2015	From the Centro Cardiologico Monzino, IRCCS, Milan, Italy (S.M., G.P., A.L.B., E.B., M.P., D.A.); Cardiology Department, Hospital de Santa Cruz, CHLO, Lisbon, Portugal (P.D.A.G.); Cardiovascular Center, Hospital da Luz, ESS, Lisbon, Portugal (P.D.A.G.); C	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Circulation.Cardiovascular imaging Periodical, Abbrev. Circ.Cardiovasc.Imaging Pub Date Free Form Feb Volume 8 Issue 2 Start Page e002332 Other Pages Notes CI: (c) 2014; JID: 101479935; CIN: Circ Cardiovasc Imaging. 2015 Feb;8(2):e003081. PMID: 25666718; OTO: NOTNLM; ppublish Place of Publication United States ISSN/ISBN 1942-0080; 1941-9651 Accession Number PMID: 25666717 Language eng SubFile Journal Article; Validation Studies; IM DOI 10.1161/CIRCIMAGING.114.002332 [doi] Output Language Unknown(0) PMID 25666717 Abstract BACKGROUND: Computed tomography-adapted Leaman score (CT-LeSc) was developed to quantify coronary CT angiography information about atherosclerotic burden (lesion localization, stenosis degree, and plaque composition). The objective of the study is to evaluate CT-LeSc long-term prognostic value in patients with suspected coronary artery disease (CAD). METHODS AND RESULTS: Single-center prospective registry including 1304 consecutive patients undergoing coronary CT angiography for suspected CAD. High CT-LeSc was defined by upper tertile (score, >5) cutoff. Segment involvement score and segment stenosis score were also evaluated. Hard cardiac events (cardiac death and nonfatal acute coronary syndromes) were considered for analysis. Different Cox regression models were used to identify independent event predictors. Kaplan-Meier event-free survival was evaluated in 4 patient subgroups stratified by obstructive (>/=50% stenosis) versus nonobstructive CAD and a high (>5) versus a low (=5) CT-LeSc. Of 1196 patients included in the final analysis (mean follow-up of 52+/-22 months), 125 patients experienced 136 hard events (18 cardiac deaths and 118 nonfatal myocardial infarction). All atherosclerotic burden scores were independent predictors of cardiac events (hazard ratios of 3.09 for segment involvement score, 4.42 for segment stenosis score, and 5.39 for CT-LeSc). Cumulative event-free survival was 76.8% with a high CT-LeSc and 96.0% with a low CT-LeSc. Event-free survival in nonobstructive CAD with high CT-LeSc (78.6%) was similar to obstructive CAD with high CT-LeSc (76.5%) but lower than obstructive CAD with low CT-LeSc (80.7%). CONCLUSIONS: CT-LeSc is an independent long-term predictor of hard cardiac events. Patients with nonobstructive CAD and high CT-LeSc had hard event-free survival similar to patients with obstructive CAD. Descriptors Links Book Title Database Publisher American Heart Association, Inc Data Source Authors Mushtaq,S., De Araujo Goncalves,P., Garcia-Garcia,H.M., Pontone,G., Bartorelli,A.L., Bertella,E., Campos,C.M., Pepi,M., Serruys,P.W., Andreini,D. Original/Translated Title URL Date of Electronic PMCID Editors
A novel real-time PCR assay for the specific identification and quantification of Weissella viridescens in blood sausages	2015	Department of Biotechnology and Food Science, University of Burgos, Pza. Misael Banuelos s/n, 09001, Burgos, Spain. Electronic address: emgomez@ubu.es.; Department of Advanced Materials, Nuclear Technology and Applied Nano/Biotechnology, University of Bur	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of food microbiology Periodical, Abbrev. Int.J.Food Microbiol. Pub Date Free Form 23-Dec Volume 215 Issue Start Page 16 Other Pages 24 Notes CI: Copyright (c) 2015; JID: 8412849; 0 (DNA Primers); OTO: NOTNLM; 2015/05/17 [received]; 2015/08/04 [revised]; 2015/08/07 [accepted]; 2015/08/16 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1879-3460; 0168-1605 Accession Number PMID: 26318409 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.ijfoodmicro.2015.08.002 [doi] Output Language Unknown(0) PMID 26318409 Abstract Weissella viridescens has been identified as one of the lactic acid bacteria (LAB) responsible for the spoilage of "morcilla de Burgos". In order to identify and quantify this bacterium in "morcilla de Burgos", a new specific PCR procedure has been developed. The primers and Taqman probe were designed on the basis of a sequence from the gene recN. To confirm the specificity of the primers, 77 strains from the genera Carnobacterium, Enterococcus, Lactobacillus, Leuconostoc, Pediococcus, Streptococcus, Vagococcus and Weissella were tested by conventional PCR. The specificity of the primers and the correct functioning of the probe was confirmed by performing real-time PCR (qPCR) with 21 W. viridescens strains and 27 strains from other LAB genera. The levels of detection and quantification for the qPCR procedure proposed herein were determined for a pure culture of W. viridescens CECT 283(T) and for "morcilla de Burgos" artificially inoculated with this species. The primers were specific for W. viridescens, with only one product of 91 bp being observed for this species. Similarly, the qPCR reactions were found to be specific, amplifying at a mean CT of 15.0+/-0.4 only for W. viridescens strains. The limit of detection (LOD) and quantification (LOQ) for this procedure was established in 0.082 pg for genomic DNA from W. viridescens. With regard to the artificially inoculated "morcilla", the limit of quantification was established in 80 CFU/reaction and the limit of detection in 8 CFU/reaction. Consequently, the qPCR developed herein can be considered to be a good, fast, simple and accurate tool for the specific detection and quantification of W. viridescens in meat samples. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Gomez-Rojo,E.M., Romero-Santacreu,L., Jaime,I., Rovira,J. Original/Translated Title URL Date of Electronic 20150816 PMCID Editors
Gender differences influence overweight smokers' experimentation with electronic nicotine delivery systems	2015	Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, United States. Electronic address: dstrong@ucsd.edu.; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States.; Department	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addictive Behaviors Periodical, Abbrev. Addict.Behav. Pub Date Free Form Oct Volume 49 Issue Start Page 20 Other Pages 25 Notes LR: 20151001; CI: Copyright (c) 2015; GR: T32 HL079891/HL/NHLBI NIH HHS/United States; JID: 7603486; NIHMS696056; OID: NLM: NIHMS696056; OID: NLM: PMC4478105; OTO: NOTNLM; 2014/08/28 [received]; 2015/04/28 [revised]; 2015/05/04 [accepted]; 2015/05/09 [ahe Place of Publication England ISSN/ISBN 1873-6327; 0306-4603 Accession Number PMID: 26036665 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.addbeh.2015.05.003 [doi] Output Language Unknown(0) PMID 26036665 Abstract INTRODUCTION: Overweight and obese tobacco users possess increased risk of cancer, diabetes, heart disease and chronic tobacco-related disease. Efforts to prevent tobacco-related health risk in this comorbid population would be informed by better understanding and monitoring of trends in the concurrent use of electronic nicotine delivery systems (ENDS) among smokers in the US marketplace. METHOD: The California Longitudinal Smokers Study (CLSS) established a cohort of current cigarette smokers in 2011 who were surveyed for tobacco use and health behavior at baseline and again in 2012 at follow-up. RESULTS: We observed a large increase in reported experimentation with ENDS. As hypothesized, overweight or obese smokers were more likely to report experimentation with ENDS, an increase that was also observed among women. Experimentation with ENDS was not associated with a reduction in use of cigarettes or a decrease in cigarette dependence in this high risk population of smokers. CONCLUSIONS: Continued surveillance of this vulnerable population is needed to better understand how experimentation with new ENDS products may impact health, facilitate switching to non-combustible tobacco or facilitate persistent cigarette dependence. Descriptors Links Book Title Database Publisher . Published by Elsevier Ltd Data Source Authors Strong,D.R., Myers,M., Linke,S., Leas,E., Hofstetter,R., Edland,S., Al-Delaimy,W.K. Original/Translated Title URL Date of Electronic 20150509 PMCID PMC4478105 Editors
A Randomized Trial of the Effect of E-cigarette TV Advertisements on Intentions to Use E-cigarettes	2015	RTI International, Research Triangle Park, North Carolina. Electronic address: mcf@rti.org.; RTI International, Research Triangle Park, North Carolina.; RTI International, Research Triangle Park, North Carolina.; RTI International, Research Triangle Park,	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Nov Volume 49 Issue 5 Start Page 686 Other Pages 693 Notes CI: Copyright (c) 2015; JID: 8704773; 2014/10/15 [received]; 2015/04/08 [revised]; 2015/05/08 [accepted]; 2015/07/07 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 26163170 Language eng SubFile Journal Article; Randomized Controlled Trial; IM DOI 10.1016/j.amepre.2015.05.010 [doi] Output Language Unknown(0) PMID 26163170 Abstract INTRODUCTION: Adolescents' use of electronic cigarettes (e-cigarettes) and exposure to e-cigarette TV advertising have increased in recent years, despite questions about their safety. The current study tests whether exposure to e-cigarette TV advertisements influences intentions to use e-cigarettes in the future and related attitudes. METHODS: A parallel-group randomized controlled experiment was conducted and analyzed in 2014 using an online survey with a convenience sample of 3,655 U.S. adolescents aged 13-17 years who had never tried e-cigarettes. Adolescents in the treatment group viewed four e-cigarette TV advertisements. RESULTS: Adolescents in the treatment group reported a greater likelihood of future e-cigarette use compared with the control group. ORs for the treatment group were 1.54 (p=0.001) for trying an e-cigarette soon; 1.43 (p=0.003) for trying an e-cigarette within the next year; and 1.29 (p=0.02) for trying an e-cigarette if a best friend offered one. Adolescents in the treatment group had higher odds of agreeing that e-cigarettes can be used in places where cigarettes are not allowed (OR=1.71, p Descriptors Links Book Title Database Publisher American Journal of Preventive Medicine. Published by Elsevier Inc Data Source Authors Farrelly,M.C., Duke,J.C., Crankshaw,E.C., Eggers,M.E., Lee,Y.O., Nonnemaker,J.M., Kim,A.E., Porter,L. Original/Translated Title URL Date of Electronic 20150707 PMCID Editors
Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome	2015	aDepartment of Internal Medicine, Division of Gastroenterology, Taipei Tzu Chi Hospital bDepartment of Internal Medicine, Division of Gastroenterology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taipei cSchool of Medicine dDepartment o	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full European journal of gastroenterology & hepatology Periodical, Abbrev. Eur.J.Gastroenterol.Hepatol. Pub Date Free Form May Volume 27 Issue 5 Start Page 516 Other Pages 522 Notes JID: 9000874; 0 (Lipoproteins, HDL); ppublish Place of Publication England ISSN/ISBN 1473-5687; 0954-691X Accession Number PMID: 25822860 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1097/MEG.0000000000000334 [doi] Output Language Unknown(0) PMID 25822860 Abstract OBJECTIVES: Gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) are highly prevalent in the general population, with significant symptom overlap, whereas the interaction between both remains poorly understood. We aim to identify the clinical and psychological factors that contribute toward the overlap of GERD and IBS. PATIENTS AND METHODS: We carried out a case-control study among 806 GERD and 176 IBS patients from a health check-up cohort (n=2604). All participants were evaluated using the Reflux Disease Questionnaire score, the Pittsburgh Sleep Quality Index score, the Taiwanese Depression Questionnaire score, and the State-Trait Anxiety Inventory score. Endoscopic findings were classified according to the Los Angeles classification. IBS was diagnosed on the basis of Rome III criteria, and metabolic syndrome was defined by the National Cholesterol Education Program Adult Treatment Panel III definition. RESULTS: Among the study population, 727 individuals had GERD, 97 individuals had IBS, and 79 individuals had a diagnosis of both GERD and IBS (GERD-I). GERD-I patients had more severe GERD symptoms compared with patients with GERD or IBS alone (P Descriptors Links Book Title Database Publisher Data Source Authors Hsu,C.S., Liu,T.T., Wen,S.H., Wang,C.C., Yi,C.H., Chen,J.H., Lei,W.Y., Orr,W.C., Fabio,P., Chen,C.L. Original/Translated Title URL Date of Electronic PMCID Editors
Crystal structures of two hydrazinecarbo-thio-amide derivatives: (E)-N-ethyl-2-[(4-oxo-4H-chromen-3-yl)methyl-idene]hydrazinecarbo-thio-amide hemi-hydrate and (E)-2-[(4-chloro-2H-chromen-3-yl)methyl-idene]-N-phenyl-hydrazinecarbo-thio-amide	2015	Department of Physics, Ethiraj College for Women (Autonomous), Chennai 600 008, India.; Department of Chemistry, National Institute of Technology, Tiruchirappalli 620 015, India.; Department of Chemistry, National Institute of Technology, Tiruchirappalli	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Crystallographic communications Periodical, Abbrev. Acta Crystallogr.E.Crystallogr.Commun. Pub Date Free Form 21-Feb Volume 71 Issue Pt 3 Start Page 305 Other Pages 308 Notes LR: 20150408; JID: 101648987; OID: NLM: PMC4350706; OTO: NOTNLM; 2015/03/01 [ecollection]; 2015/02/04 [received]; 2015/02/17 [accepted]; 2015/02/21 [epublish]; epublish Place of Publication England ISSN/ISBN 2056-9890 Accession Number PMID: 25844194 Language eng SubFile Journal Article DOI 10.1107/S2056989015003369 [doi] Output Language Unknown(0) PMID 25844194 Abstract The title compounds, C13H13N3O2S.0.5H2O, (I), and C17H14ClN3OS, (II), are hydrazinecarbo-thio-amide derivatives. Compound (I) crystallizes with two independent mol-ecules (A and B) and a water mol-ecule of crystallization in the asymmetric unit. The chromene moiety is essentially planar in mol-ecules A and B, with maximum deviations of 0.028 (3) and 0.016 (3) A, respectively, for the carbonyl C atoms. In (II), the pyran ring of the chromene moiety adopts a screw-boat conformation and the phenyl ring is inclined by 61.18 (9) degrees to its mean plane. In the crystal of (I), bifurcated N-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredO hydrogen bonds link the two independent mol-ecules forming A-B dimers with two R 2 (1)(6) ring motifs, and R 2 (2)(10) and R 2 (2)(14) ring motifs. In addition to these, the water mol-ecule forms tetra-furcated hydrogen bonds which alternately generate R 4 (4)(12) and R 6 (6)(22) graph-set ring motifs. There are also pi-pi [inter-centroid distances = 3.5648 (14) and 3.6825 (15) A] inter-actions present, leading to the formation of columns along the c-axis direction. In the crystal of (II), mol-ecules are linked by pairs of N-Hcdots, three dots, centeredS hydrogen bonds, forming inversion dimers with an R 2 (2)(8) ring motif. The dimers are linked by C-Hcdots, three dots, centeredpi inter-actions, forming ribbons lying parallel to (210). Descriptors Links Book Title Database Publisher Data Source Authors Gangadharan,R., Haribabu,J., Karvembu,R., Sethusankar,K. Original/Translated Title URL Date of Electronic 20150221 PMCID PMC4350706 Editors
Lack of attentional retraining effects in cigarette smokers attempting cessation: a proof of concept double-blind randomised controlled trial	2015	UK Centre for Tobacco and Alcohol Studies, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK. Electronic address: rachna.begh@phc.ox.ac.uk.; UK Centre for Tobacco and Alcohol Studies, School of Experimental Psyc	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Drug and alcohol dependence Periodical, Abbrev. Drug Alcohol Depend. Pub Date Free Form 1-Apr Volume 149 Issue Start Page 158 Other Pages 165 Notes LR: 20160805; CI: Copyright (c) 2015; ISRCTN/ISRCTN54375405; GR: MC_UU_12013/6/Medical Research Council/United Kingdom; JID: 7513587; EMS69300; OID: NLM: EMS69300; OID: NLM: PMC4961243; OTO: NOTNLM; 2014/10/02 [received]; 2015/01/20 [revised]; 2015/01/28 Place of Publication Ireland ISSN/ISBN 1879-0046; 0376-8716 Accession Number PMID: 25697911 Language eng SubFile Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.drugalcdep.2015.01.041 [doi] Output Language Unknown(0) PMID 25697911 Abstract BACKGROUND: Observational studies have shown that attentional bias for smoking-related cues is associated with increased craving and relapse. Laboratory experiments have shown that manipulating attentional bias may change craving. Interventions to reduce attentional bias could reduce relapse in smokers seeking to quit. We report a clinical trial of attentional retraining in treatment-seeking smokers. METHODS: This was a double-blind randomised controlled trial that took place in UK smoking cessation clinics. Smokers interested in quitting were randomised to five weekly sessions of attentional retraining (N=60) or placebo training (N = 58) using a modified visual probe task from one week prior to quit day. Both groups received 21 mg nicotine patches (from quit day onwards) and behavioural support. Primary outcomes included change in attentional bias reaction times four weeks after quit day on the visual probe task and craving measured weekly using the Mood and Physical Symptoms Scale. Secondary outcomes were changes in withdrawal symptoms, time to first lapse and prolonged abstinence. RESULTS: No attentional bias towards smoking cues was found in the sample at baseline (mean difference = 3 ms, 95% CI = -2, 9). Post-training bias was not significantly lower in the retraining group compared with the placebo group (mean difference = -9 ms, 95% CI = -20, 2). There was no difference between groups in change in craving (p = 0.89) and prolonged abstinence at four weeks (risk ratio = 1.00, 95% CI = 0.70, 1.43). CONCLUSIONS: Taken with one other trial, there appears to be no effect from clinic-based attentional retraining using the visual probe task. Attentional retraining conducted out of clinic may prove more effective. CLINICAL TRIAL REGISTRATION: UK Clinical Trials ISRCTN 54375405. Descriptors Links Book Title Database Publisher Elsevier Ireland Ltd Data Source Authors Begh,R., Munafo,M.R., Shiffman,S., Ferguson,S.G., Nichols,L., Mohammed,M.A., Holder,R.L., Sutton,S., Aveyard,P. Original/Translated Title URL Date of Electronic 20150209 PMCID PMC4961243 Editors

E-mail