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Title	Pub Year	Author Sort descending	SearchLink
Additive antifungal activity of anidulafungin and human neutrophils against Candida parapsilosis biofilms	2011	Laboratory of Infectious Diseases, 3rd Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of antimicrobial chemotherapy Periodical, Abbrev. J.Antimicrob.Chemother. Pub Date Free Form Mar Volume 66 Issue 3 Start Page 588 Other Pages 591 Notes LR: 20130527; JID: 7513617; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Tetrazolium Salts); 0 (Triazoles); 117038-70-7 (2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazoliu m hydroxide); 9HLM53094I (anidulafungin); 2010/12/07 Place of Publication England ISSN/ISBN 1460-2091; 0305-7453 Accession Number PMID: 21138910 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/jac/dkq466 [doi] Output Language Unknown(0) PMID 21138910 Abstract OBJECTIVES: To investigate the activities of two newer triazoles and two echinocandins combined with human phagocytes against Candida parapsilosis biofilms. METHODS: An in vitro model of C. parapsilosis biofilms was used. Biofilms were grown on silicone elastomer discs in 96-well plates at 37 degrees C for 72 h. Biofilms or planktonic cells were incubated with voriconazole, posaconazole, caspofungin or anidulafungin, at clinically relevant concentrations, and human phagocytes (neutrophils or monocytes) alone or in combination with each of the antifungal agents for a further 22 h. Fungal damage induced by antifungal agents and/or phagocytes was determined by XTT [2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)2H-tetrazolium-5-carboxanilide] metabolic assay. RESULTS: Each of the antifungal agents alone and in combination with human phagocytes induced less damage against C. parapsilosis biofilms compared with planktonic cells. No antagonistic interactions between antifungal agents and phagocytes were found. Furthermore, anidulafungin, but not caspofungin, and neutrophils exerted additive activity against C. parapsilosis biofilms. CONCLUSIONS: Besides a lack of antagonistic interactions between newer antifungal agents and phagocytes, anidulafungin exerts additive immunopharmacological activity against C. parapsilosis biofilms. Descriptors Links Book Title Database Publisher Data Source Authors Katragkou,A., Chatzimoschou,A., Simitsopoulou,M., Georgiadou,E., Roilides,E. Original/Translated Title URL Date of Electronic 20101207 PMCID Editors
Caspofungin at catheter lock concentrations eradicates mature biofilms of Candida lusitaniae and Candida guilliermondii	2014	Laboratory of Infectious Diseases, 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece.; Laboratory of Infectious Diseases, 3rd Department of Pediatrics, Faculty of	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Aug Volume 58 Issue 8 Start Page 4953 Other Pages 4956 Notes LR: 20150201; CI: Copyright (c) 2014; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Lipopeptides); 0 (liposomal amphotericin B); 7XU7A7DROE (Amphotericin B); 9HLM53094I (anidulafungin); F0XDI6ZL63 (caspofungin); R10H71BSWG (micafungin); OID: Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 24890585 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AAC.03117-14 [doi] Output Language Unknown(0) PMID 24890585 Abstract The antibiofilm activities of caspofungin, anidulafungin, micafungin, and liposomal amphotericin B were studied against Candida lusitaniae, Candida guilliermondii, and a Candida albicans control strain. While anidulafungin and micafungin (0.007 to 2,048 mg/liter) showed reduced activity against biofilms of both test species, caspofungin displayed concentration-dependent antibiofilm activity, reaching complete and persistent eradication at concentrations achievable during lock therapy (512 to 2,048 mg/liter, P Descriptors Links Book Title Database Publisher American Society for Microbiology. All Rights Reserved Data Source Authors Simitsopoulou,M., Kyrpitzi,D., Velegraki,A., Walsh,T.J., Roilides,E. Original/Translated Title URL Date of Electronic 20140602 PMCID PMC4136003 Editors
Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms	2008	Laboratory of Infectious Diseases, Third Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Jan Volume 52 Issue 1 Start Page 357 Other Pages 360 Notes LR: 20140904; JID: 0315061; 0 (Antifungal Agents); 0 (Azoles); 0 (Echinocandins); OID: NLM: PMC2223899; 2007/10/15 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 0066-4804; 0066-4804 Accession Number PMID: 17938192 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI AAC.00856-07 [pii] Output Language Unknown(0) PMID 17938192 Abstract The activities of voriconazole, posaconazole, caspofungin, and anidulafungin against Candida albicans and Candida parapsilosis biofilms were evaluated. In contrast to planktonic cells, the MICs for voriconazole and posaconazole for the biofilms of the two species were high (>or=256 and >64 mg/liter, respectively) but relatively low for the echinocandins caspofungin and anidulafungin (<or=1 and <or=2 mg/liter, respectively). Descriptors Antifungal Agents/pharmacology, Azoles/pharmacology, Biofilms/drug effects, Candida/classification/drug effects, Candida albicans/drug effects, Echinocandins/pharmacology, Humans, Microbial Sensitivity Tests Links Book Title Database Publisher Data Source Authors Katragkou,A., Chatzimoschou,A., Simitsopoulou,M., Dalakiouridou,M., Diza-Mataftsi,E., Tsantali,C., Roilides,E. Original/Translated Title URL Date of Electronic 20071015 PMCID PMC2223899 Editors
Diversity, dynamics, and activity of bacterial communities during production of an artisanal Sicilian cheese as evaluated by 16S rRNA analysis	2002	Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, 6703 CT Wageningen, The Netherlands.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Applied and Environmental Microbiology Periodical, Abbrev. Appl.Environ.Microbiol. Pub Date Free Form Apr Volume 68 Issue 4 Start Page 1882 Other Pages 1892 Notes LR: 20140612; JID: 7605801; 0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S); OID: NLM: PMC123848; ppublish Place of Publication United States ISSN/ISBN 0099-2240; 0099-2240 Accession Number PMID: 11916708 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI Output Language Unknown(0) PMID 11916708 Abstract The diversity and dynamics of the microbial communities during the manufacturing of Ragusano cheese, an artisanal cheese produced in Sicily (Italy), were investigated by a combination of classical and culture-independent approaches. The latter included PCR, reverse transcriptase-PCR (RT-PCR), and denaturing gradient gel electrophoresis (DGGE) of 16S rRNA genes (rDNA). Bacterial and Lactobacillus group-specific primers were used to amplify the V6 to V8 and V1 to V3 regions of the 16S rRNA gene, respectively. DGGE profiles from samples taken during cheese production indicated dramatic shifts in the microbial community structure. Cloning and sequencing of rDNA amplicons revealed that mesophilic lactic acid bacteria (LAB), including species of Leuconostoc, Lactococcus lactis, and Macrococcus caseolyticus were dominant in the raw milk, while Streptococcus thermophilus prevailed during lactic fermentation. Other thermophilic LAB, especially Lactobacillus delbrueckii and Lactobacillus fermentum, also flourished during ripening. Comparison of the rRNA-derived patterns obtained by RT-PCR to the rDNA DGGE patterns indicated a substantially different degree of metabolic activity for the microbial groups detected. Identification of cultivated LAB isolates by phenotypic characterization and 16S rDNA analysis indicated a variety of species, reflecting to a large extent the results obtained from the 16S rDNA clone libraries, with the significant exception of the Lactobacillus delbrueckii species, which dominated in the ripening cheese but was not detected by cultivation. The present molecular approaches combined with culture can effectively describe the complex ecosystem of natural fermented dairy products, giving useful information for starter culture design and preservation of artisanal fermented food technology. Descriptors Cheese/microbiology, Colony Count, Microbial, DNA, Bacterial/analysis, Ecosystem, Electrophoresis, Polyacrylamide Gel/methods, Genetic Variation, Gram-Positive Bacteria/classification/genetics/isolation & purification, Lactobacillus, Leuconostoc, Polymerase Chain Reaction, RNA, Ribosomal, 16S/genetics, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA Links Book Title Database Publisher Data Source Authors Randazzo,C. L., Torriani,S., Akkermans,A. D., de Vos,W. M., Vaughan,E. E. Original/Translated Title URL Date of Electronic PMCID PMC123848 Editors
Influence of geographical origin and flour type on diversity of lactic acid bacteria in traditional Belgian sourdoughs	2007	Laboratory of Microbiology, Department of Biochemistry, Physiology and Microbiology, Ghent University, K. L. Ledeganckstraat 35, B-9000 Ghent, Belgium. Ilse.Scheirlinck@ugent.be	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Applied and Environmental Microbiology Periodical, Abbrev. Appl.Environ.Microbiol. Pub Date Free Form Oct Volume 73 Issue 19 Start Page 6262 Other Pages 6269 Notes LR: 20140904; JID: 7605801; 0 (Bacterial Proteins); 0 (DNA, Bacterial); EC 6.1.1.20 (Phenylalanine-tRNA Ligase); OID: NLM: PMC2075033; 2007/08/03 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 0099-2240; 0099-2240 Accession Number PMID: 17675431 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI AEM.00894-07 [pii] Output Language Unknown(0) PMID 17675431 Abstract A culture-based approach was used to investigate the diversity of lactic acid bacteria (LAB) in Belgian traditional sourdoughs and to assess the influence of flour type, bakery environment, geographical origin, and technological characteristics on the taxonomic composition of these LAB communities. For this purpose, a total of 714 LAB from 21 sourdoughs sampled at 11 artisan bakeries throughout Belgium were subjected to a polyphasic identification approach. The microbial composition of the traditional sourdoughs was characterized by bacteriological culture in combination with genotypic identification methods, including repetitive element sequence-based PCR fingerprinting and phenylalanyl-tRNA synthase (pheS) gene sequence analysis. LAB from Belgian sourdoughs belonged to the genera Lactobacillus, Pediococcus, Leuconostoc, Weissella, and Enterococcus, with the heterofermentative species Lactobacillus paralimentarius, Lactobacillus sanfranciscensis, Lactobacillus plantarum, and Lactobacillus pontis as the most frequently isolated taxa. Statistical analysis of the identification data indicated that the microbial composition of the sourdoughs is mainly affected by the bakery environment rather than the flour type (wheat, rye, spelt, or a mixture of these) used. In conclusion, the polyphasic approach, based on rapid genotypic screening and high-resolution, sequence-dependent identification, proved to be a powerful tool for studying the LAB diversity in traditional fermented foods such as sourdough. Descriptors Bacterial Proteins/analysis/genetics, Bacterial Typing Techniques, Belgium, DNA Fingerprinting, DNA, Bacterial, Fermentation, Flour/classification/microbiology, Genetic Variation, Geography, Lactobacillus/classification/genetics/isolation & purification, Phenylalanine-tRNA Ligase/genetics Links Book Title Database Publisher Data Source Authors Scheirlinck,I., Van der Meulen,R., Van Schoor,A., Vancanneyt,M., De Vuyst,L., Vandamme,P., Huys,G. Original/Translated Title URL Date of Electronic 20070803 PMCID PMC2075033 Editors
Taxonomic structure and stability of the bacterial community in belgian sourdough ecosystems as assessed by culture and population fingerprinting	2008	Laboratory of Microbiology, Ghent University, K.L. Ledeganckstraat 35, 9000 Ghent, Belgium. ilse.scheirlinck@ugent.be	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Applied and Environmental Microbiology Periodical, Abbrev. Appl.Environ.Microbiol. Pub Date Free Form Apr Volume 74 Issue 8 Start Page 2414 Other Pages 2423 Notes LR: 20140904; GENBANK/AM901454; GENBANK/AM901455; GENBANK/AM901456; GENBANK/AM901457; GENBANK/AM901458; GENBANK/AM901459; GENBANK/AM901460; GENBANK/AM901461; GENBANK/AM901462; GENBANK/AM901463; GENBANK/AM901464; GENBANK/AM901465; GENBANK/AM901466; GENBANK Place of Publication United States ISSN/ISBN 1098-5336; 0099-2240 Accession Number PMID: 18310426 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AEM.02771-07 [doi] Output Language Unknown(0) PMID 18310426 Abstract A total of 39 traditional sourdoughs were sampled at 11 bakeries located throughout Belgium which were visited twice with a 1-year interval. The taxonomic structure and stability of the bacterial communities occurring in these traditional sourdoughs were assessed using both culture-dependent and culture-independent methods. A total of 1,194 potential lactic acid bacterium (LAB) isolates were tentatively grouped and identified by repetitive element sequence-based PCR, followed by sequence-based identification using 16S rRNA and pheS genes from a selection of genotypically unique LAB isolates. In parallel, all samples were analyzed by denaturing gradient gel electrophoresis (DGGE) of V3-16S rRNA gene amplicons. In addition, extensive metabolite target analysis of more than 100 different compounds was performed. Both culturing and DGGE analysis showed that the species Lactobacillus sanfranciscensis, Lactobacillus paralimentarius, Lactobacillus plantarum, and Lactobacillus pontis dominated the LAB population of Belgian type I sourdoughs. In addition, DGGE band sequence analysis demonstrated the presence of Acetobacter sp. and a member of the Erwinia/Enterobacter/Pantoea group in some samples. Overall, the culture-dependent and culture-independent approaches each exhibited intrinsic limitations in assessing bacterial LAB diversity in Belgian sourdoughs. Irrespective of the LAB biodiversity, a large majority of the sugar and amino acid metabolites were detected in all sourdough samples. Principal component-based analysis of biodiversity and metabolic data revealed only little variation among the two samples of the sourdoughs produced at the same bakery. The rare cases of instability observed could generally be linked with variations in technological parameters or differences in detection capacity between culture-dependent and culture-independent approaches. Within a sampling interval of 1 year, this study reinforces previous observations that the bakery environment rather than the type or batch of flour largely determines the development of a stable LAB population in sourdoughs. Descriptors Acetobacter/chemistry/classification/genetics/isolation & purification, Amino Acids/analysis, Belgium, Biodiversity, Carbohydrates/analysis, DNA Fingerprinting, DNA, Bacterial/chemistry/genetics, DNA, Ribosomal/chemistry/genetics, Ecosystem, Electrophoresis, Polyacrylamide Gel, Enterobacteriaceae/chemistry/classification/genetics/isolation & purification, Flour/microbiology, Food Microbiology, Interspersed Repetitive Sequences, Lactobacillus/chemistry/classification/genetics/isolation & purification, Molecular Sequence Data, Nucleic Acid Denaturation, Polymerase Chain Reaction, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA Links Book Title Database Publisher Data Source Authors Scheirlinck,I., Van der Meulen,R., Van Schoor,A., Vancanneyt,M., De Vuyst,L., Vandamme,P., Huys,G. Original/Translated Title URL Date of Electronic 20080229 PMCID PMC2293155 Editors
Detailed comparison of Candida albicans and Candida glabrata biofilms under different conditions and their susceptibility to caspofungin and anidulafungin	2011	Laboratory of Molecular Cell Biology, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of medical microbiology Periodical, Abbrev. J.Med.Microbiol. Pub Date Free Form Sep Volume 60 Issue Pt 9 Start Page 1261 Other Pages 1269 Notes LR: 20130527; JID: 0224131; 0 (Antifungal Agents); 0 (Culture Media); 0 (Echinocandins); 0 (Fungal Proteins); 0 (Polystyrenes); 9HLM53094I (anidulafungin); F0XDI6ZL63 (caspofungin); 2011/05/12 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1473-5644; 0022-2615 Accession Number PMID: 21566087 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1099/jmm.0.032037-0 [doi] Output Language Unknown(0) PMID 21566087 Abstract Candida biofilm development can be influenced by diverse factors such as substrate, culture medium, carbohydrate source and pH. We have analysed biofilm formation of Candida albicans SC5314 and Candida glabrata ATCC 2001 wild-type strains in the presence of different media (RPMI 1640 versus YNB) and using different pH values (pH 5.6 or 7.0). We determined adhesion and biofilm formation on polystyrene, changes in the expression of adhesin genes during these processes and the susceptibility of mature biofilms to echinocandins. Biofilms formed on polystyrene by both Candida species proved to be influenced strongly by the composition of the medium rather than pH. C. albicans and C. glabrata formed thicker biofilms in RPMI 1640 medium, whereas in YNB medium, both species manifested adhesion rather than characteristic multilayer biofilm architecture. The stimulated biofilm formation in RPMI 1640 medium at pH 7.0 corroborated positively with increased expression of adhesin genes, essential to biofilm formation in vitro, including ALS3 and EAP1 in C. albicans and EPA6 in C. glabrata. The thicker biofilms grown in RPMI 1640 medium were more tolerant to caspofungin and anidulafungin than YNB-grown biofilms. We also observed that mature C. glabrata biofilms were less susceptible in RPMI 1640 medium to echinocandins than C. albicans biofilms. Environmental conditions, i.e. medium and pH, can significantly affect not only biofilm architecture, but also the expression profile of several genes involved during the different stages of biofilm development. In addition, growth conditions may also influence the antifungal-susceptibility profile of fungal populations within biofilm structures. Therefore, before designing any experimental biofilm set-up, it is important to consider the potential influence of external environmental factors on Candida biofilm development. Descriptors Links Book Title Database Publisher Data Source Authors Kucharikova,S., Tournu,H., Lagrou,K., Van Dijck,P., Bujdakova,H. Original/Translated Title URL Date of Electronic 20110512 PMCID Editors
Lung function profiles and aerobic capacity of adult cigarette and hookah smokers after 12 weeks intermittent training	2015	Laboratory of Pharmacology, Faculty of Medicine of Sfax, University of Sfax, Sfax, Tunisia.; Research Unit (EM2S), Higher Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia.; Laboratory of Cardio-Circulatory, Respiratory,	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Libyan journal of medicine Periodical, Abbrev. Libyan J.Med. Pub Date Free Form 17-Feb Volume 10 Issue Start Page 26680 Other Pages Notes LR: 20151028; JID: 101299403; CIN: Libyan J Med. 2015;10:27760. PMID: 25920102; CIN: Libyan J Med. 2015;10:27760. PMID: 25906843; OID: NLM: PMC4332739; OTO: NOTNLM; 2015 [ecollection]; 2014/11/19 [received]; 2015/01/17 [revised]; 2015/01/19 [accepted]; ep Place of Publication Sweden ISSN/ISBN 1819-6357; 1819-6357 Accession Number PMID: 25694204 Language eng SubFile Journal Article; IM DOI 10.3402/ljm.v10.26680 [doi] Output Language Unknown(0) PMID 25694204 Abstract INTRODUCTION: Pulmonary function is compromised in most smokers. Yet it is unknown whether exercise training improves pulmonary function and aerobic capacity in cigarette and hookah smokers and whether these smokers respond in a similar way as do non-smokers. AIM: To evaluate the effects of an interval exercise training program on pulmonary function and aerobic capacity in cigarette and hookah smokers. METHODS: Twelve cigarette smokers, 10 hookah smokers, and 11 non-smokers participated in our exercise program. All subjects performed 30 min of interval exercise (2 min of work followed by 1 min of rest) three times a week for 12 weeks at an intensity estimated at 70% of the subject's maximum aerobic capacity (VO2max). Pulmonary function was measured using spirometry, and maximum aerobic capacity was assessed by maximal exercise testing on a treadmill before the beginning and at the end of the exercise training program. RESULTS: As expected, prior to the exercise intervention, the cigarette and hookah smokers had significantly lower pulmonary function than the non-smokers. The 12-week exercise training program did not significantly affect lung function as assessed by spirometry in the non-smoker group. However, it significantly increased both forced expiratory volume in 1 second and peak expiratory flow (PEF) in the cigarette smoker group, and PEF in the hookah smoker group. Our training program had its most notable impact on the cardiopulmonary system of smokers. In the non-smoker and cigarette smoker groups, the training program significantly improved VO2max (4.4 and 4.7%, respectively), v VO2max (6.7 and 5.6%, respectively), and the recovery index (7.9 and 10.5%, respectively). CONCLUSIONS: After 12 weeks of interval training program, the increase of VO2max and the decrease of recovery index and resting heart rate in the smoking subjects indicated better exercise tolerance. Although the intermittent training program altered pulmonary function only partially, both aerobic capacity and life quality were improved. Intermittent training should be advised in the clinical setting for subjects with adverse health behaviors. Descriptors Links Book Title Database Publisher Data Source Authors Koubaa,A., Triki,M., Trabelsi,H., Masmoudi,L., Zeghal,K.N., Sahnoun,Z., Hakim,A. Original/Translated Title URL Date of Electronic 20150217 PMCID PMC4332739 Editors
The effect of a 12-week moderate intensity interval training program on the antioxidant defense capability and lipid profile in men smoking cigarettes or hookah: a cohort study	2015	Laboratory of Pharmacology, Sfax Medicine Faculty SMF, Avenue Majida Boulila, 3029 Sfax, Tunisia ; Laboratory of Cardio-Circulatory, Respiratory, and Hormonal Adaptations to Muscular Exercise, Ibn El Jazzar Medicine Faculty, Avenue Mohamed Karoui, 4002 So	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full TheScientificWorldJournal Periodical, Abbrev. ScientificWorldJournal Pub Date Free Form Volume 2015 Issue Start Page 639369 Other Pages Notes LR: 20150212; JID: 101131163; 0 (Lipids); 4Y8F71G49Q (Malondialdehyde); EC 1.11.1.9 (Glutathione Peroxidase); EC 1.15.1.1 (Superoxide Dismutase); EC 1.8.1.7 (Glutathione Reductase); H4N855PNZ1 (alpha-Tocopherol); OID: NLM: PMC4310461; 2014/07/25 [received Place of Publication United States ISSN/ISBN 1537-744X; 1537-744X Accession Number PMID: 25664340 Language eng SubFile Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1155/2015/639369 [doi] Output Language Unknown(0) PMID 25664340 Abstract AIM: To examine the impact of interval training program on the antioxidant defense capability and lipid profile in men smoking cigarettes or hookah unable or unwilling to quit smoking. METHODS: Thirty-five participants performed an interval training (2 : 1 work : rest ratio) 3 times a week for 12 weeks at an intensity of 70% of VO2max. All subjects were subjected to a biochemical test session before and after the training program. RESULTS: The increase of total antioxidant status (TAS), glutathione peroxidase (GPx), and alpha-tocopherol, is significant only for cigarette smokers (CS) and hookah smokers (HS) groups. The decrease of malondialdehyde (MDA) and the increase of glutathione reductase (GR) are more pronounced in smokers groups compared to those of nonsmokers (NS). Superoxide dismutase (SOD) increases in NS, CS, and HS groups by 10.1%, 19.5%, and 13.3%, respectively (P Descriptors Links Book Title Database Publisher Data Source Authors Koubaa,A., Triki,M., Trabelsi,H., Baati,H., Sahnoun,Z., Hakim,A. Original/Translated Title URL Date of Electronic 20150114 PMCID PMC4310461 Editors
Changes in Antioxidant Defense Capability and Lipid Profile after 12-Week Low- Intensity Continuous Training in Both Cigarette and Hookah Smokers: A Follow-Up Study	2015	Laboratory of Pharmacology, Sfax Medicine Faculty SMF, Avenue Majida Boulila, Sfax, 3029, Tunisia; Research Unit (EM2S), Sfax Institute of Sport and Physical Education, Airport Road, P.O Box 384, Sfax, 3000, Tunisia.; Laboratory of cardio-circulatory, res	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PloS one Periodical, Abbrev. PLoS One Pub Date Free Form 29-Jun Volume 10 Issue 6 Start Page e0130563 Other Pages Notes LR: 20150703; JID: 101285081; 0 (Antioxidants); 0 (Lipids); OID: NLM: PMC4488294; 2015 [ecollection]; 2015/03/27 [received]; 2015/05/21 [accepted]; 2015/06/29 [epublish]; epublish Place of Publication United States ISSN/ISBN 1932-6203; 1932-6203 Accession Number PMID: 26121249 Language eng SubFile Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1371/journal.pone.0130563 [doi] Output Language Unknown(0) PMID 26121249 Abstract To examine the impact of low-intensity continuous training program on antioxidant defense capability and lipid profile in male cigarette or hookah smokers. Forty-three male adults participated in a 12-week continuous training program at an intensity of 40% of VO2max. All subjects were subjected to anthropometric, physical and biochemical tests before and after the training program. The increase of Glutathione reductase (GR) and Superoxide dismutase (SOD) is significant only for cigarette smokers (CS) and hookah smokers (HS) groups. The Malondialdehyde (MDA) decrease and alpha-tocopherol increase are significant only for HS group. GPx was increased in NS, CS and HS by 2.6% (p Descriptors Links Book Title Database Publisher Data Source Authors Koubaa,A., Triki,M., Trabelsi,H., Masmoudi,L., Sahnoun,Z., Hakim,A. Original/Translated Title URL Date of Electronic 20150629 PMCID PMC4488294 Editors

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