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Determination of risk for Barrett's esophagus and esophageal adenocarcinoma 2016 aDepartment of Medicine, Section of Gastroenterology and HepatologybDan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
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Journal Article
Periodical, Full
Current opinion in gastroenterology
Periodical, Abbrev.
Curr.Opin.Gastroenterol.
Pub Date Free Form
Jul
Volume
32
Issue
4
Start Page
319
Other Pages
324
Notes
JID: 8506887; ppublish
Place of Publication
United States
ISSN/ISBN
1531-7056; 0267-1379
Accession Number
PMID: 27276368
Language
eng
SubFile
Journal Article; IM
DOI
10.1097/MOG.0000000000000274 [doi]
Output Language
Unknown(0)
PMID
27276368
Abstract
PURPOSE OF REVIEW: The incidence of esophageal adenocarcinoma and its precursor, Barrett's esophagus, have increased greatly over the past 40 years and continue to rise. This report summarizes the most recent data on the risk factors for Barrett's esophagus and esophageal adenocarcinoma. RECENT FINDINGS: Other factors, highly correlated with increasing trends for obesity, are the dominant driver of the increase in incidence of esophageal adenocarcinoma, interacting with gastroesophageal reflux disease symptoms. Abdominal obesity, independently of gastroesophageal reflux disease symptoms, is associated with increased risk of Barrett's esophagus and this association is likely mediated by high levels of leptin and insulin. Use of aspirin, nonsteroidal anti-inflammatory drugs, statins, and proton pump inhibitors are associated with a reduced risk of Barrett's esophagus as well as lower risk of neoplastic progression in patients with Barrett's esophagus. An increasing number of genetic loci have been associated with risk of Barrett's esophagus and esophageal adenocarcinoma. SUMMARY: Recent advances in identifying risk factors and reporting of more precise estimates of effect for the main risk factors will positively impact clinical risk stratification efforts for Barrett's esophagus and esophageal adenocarcinoma. Large pooling studies are underway to derive and validate reliable clinical risk models.
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Data Source
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Thrift,A.P.
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URL
Date of Electronic
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons using lab on valve dispersive liquid-liquid microextraction coupled to high performance chromatography 2015 Department of Chemistry, University of the Balearic Islands, 07122 Palma de Mallorca, Spain.; Department of Chemistry, University of the Balearic Islands, 07122 Palma de Mallorca, Spain.; Department of Chemistry, University of the Balearic Islands, 07122
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Print(0)
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Journal Article
Periodical, Full
Talanta
Periodical, Abbrev.
Talanta
Pub Date Free Form
1-Jun
Volume
138
Issue
Start Page
190
Other Pages
195
Notes
CI: Copyright (c) 2015; JID: 2984816R; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); OTO: NOTNLM; 2014/10/27 [received]; 2015/01/28 [revised]; 2015/02/03 [accepted]; 2015/02/11 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1873-3573; 0039-9140
Accession Number
PMID: 25863390
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.talanta.2015.02.007 [doi]
Output Language
Unknown(0)
PMID
25863390
Abstract
In this work, dispersive liquid-liquid microextraction (DLLME) method was applied for high performance liquid chromatography (HPLC) determination of 15 PAHs in aqueous matrices.The extraction procedure was automated using a system of multisyringe flow injection analysis coupled to HPLC instrument with fluorescence detector. Factors affecting the extraction process, such as type and volume of extraction and dispersive solvent, extraction time and centrifugation step were investigated thoroughly and optimized utilizing factorial design. The best recovery was achieved using 100 microL of trichloroethylene as the extraction solvent and 900 microL of acetonitrile as the dispersive solvent.The results showed that extraction time has no effect on the recovery of PAHs. The enrichment factors of PAHs were in the range of 86-95 with limits of detection of 0.02-0.6 microg L(-1). The linearity was 0.2-600 microg L(-1) for different PAHs. The relative standard deviation (RSD) for intra- and inter-day of extraction of PAHs were in the range of 1.6-4.7 and 2.1-5.3, respectively, for five measurements.The developed method was used to assess the occurrence of 15 PAHs in tap water, rain waters and river surface waters samples.
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Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Fernandez,M., Clavijo,S., Forteza,R., Cerda,V.
Original/Translated Title
URL
Date of Electronic
20150211
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in waters by ultrasound-assisted emulsification-microextraction and gas chromatography-mass spectrometry 2010 Selcuk University, Department of Environmental Engineering, Campus, 42031 Konya, Turkey. sozcan@selcuk.edu.tr
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Print(0)
Ref Type
Journal Article
Periodical, Full
Analytica Chimica Acta
Periodical, Abbrev.
Anal.Chim.Acta
Pub Date Free Form
30-Apr
Volume
665
Issue
2
Start Page
193
Other Pages
199
Notes
CI: Copyright 2010; JID: 0370534; 2009/11/24 [received]; 2010/03/23 [revised]; 2010/03/23 [accepted]; 2010/03/29 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1873-4324; 0003-2670
Accession Number
PMID: 20417330
Language
eng
SubFile
Journal Article
DOI
10.1016/j.aca.2010.03.047 [doi]
Output Language
Unknown(0)
PMID
20417330
Abstract
An ultrasound-assisted emulsification-microextraction (USAEME) procedure was developed for the extraction of US EPA 16 polycyclic aromatic hydrocarbons (PAHs) in 10 mL of water samples, with subsequent determination by gas chromatography-mass spectrometry (GC-MS). After determination of the most suitable solvent and solvent volume, several other parameters (i.e., extraction time, centrifugation time and ionic strength of the sample) were optimized using a 2(3) factorial experimental design. Limits of detection ranged from 0.001 to 0.036 microg L(-1). The developed procedure was applied to fortified distilled water with different fortification levels (0.5, 2 and 5 microg L(-1)). Recoveries were over 92% and relative standard deviations of the recoveries were below 8%. The efficiency of the USAEME was compared with traditional liquid-liquid extraction (LLE) and solid-phase extraction on real water samples (i.e., tap water, well water and surface (lake) water as well as domestic and industrial wastewaters). The USAEME showed comparable efficiencies especially with LLE. The developed USAEME was demonstrated to be robust, viable, simple, rapid and easy to use for the determination of PAHs in water samples by GC-MS.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Ozcan,S., Tor,A., Aydin,M. E.
Original/Translated Title
URL
Date of Electronic
20100329
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in water samples using online microextraction by packed sorbent coupled with gas chromatography-mass spectrometry 2012 Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China.
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Print(0)
Ref Type
Journal Article
Periodical, Full
Talanta
Periodical, Abbrev.
Talanta
Pub Date Free Form
30-May
Volume
94
Issue
Start Page
152
Other Pages
157
Notes
CI: Copyright (c) 2012; JID: 2984816R; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); 2012/01/13 [received]; 2012/02/27 [revised]; 2012/03/04 [accepted]; 2012/03/10 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1873-3573; 0039-9140
Accession Number
PMID: 22608428
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.talanta.2012.03.010 [doi]
Output Language
Unknown(0)
PMID
22608428
Abstract
A fully automated microextraction by packed sorbents (MEPS) coupled with large volume injection gas chromatography-mass spectrometry (GC-MS) has been developed for the determination of eight polycyclic aromatic hydrocarbons (PAHs) in environmental water samples. Naphthalene (Nap), pyrene (Pyr), anthracene, acenaphthylene, phenanthrene, fluoranthene (Flr), fluorene and acenaphthene were the PAHs studied. The performance of the microextraction-GC-MS protocol was compared with solid phase extraction (SPE) and GC-MS analysis. Under optimized experimental conditions, the methods were linear for all analytes in the following ranges: 0.05-2.0 mug L(-1) (MEPS) and 0.25-10.0 mug L(-1) (SPE). The correlation coefficients (R(2)) were in the range 0.9965-0.9997 (MEPS) and 0.9978-0.9998 (SPE) for all the analytes. Limits of detection (LODs) for 2 mL samples (MEPS) ranged from 0.8 ng L(-1) to 8.2 ng L(-1). LODs for 50 mL samples (SPE) were between 4.8 ng L(-1) and 35.9 ng L(-1). The two methods were successfully applied to the determination of the 8 PAHs in environmental waters, with recoveries in the range of 70-117% (MEPS) and 72-134% (SPE) for a real spiked sample. The two sample preparation processes showed good repeatabilities with intra-day relative standard deviations below 14.0% (MEPS) and 14.6% (SPE). Nap, Flr and Pyr were found in a river water sample.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Fu,S., Fan,J., Hashi,Y., Chen,Z.
Original/Translated Title
URL
Date of Electronic
20120310
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in water by a novel mesoporous-coated stainless steel wire microextraction combined with HPLC 2010 College of Chemistry and Chemical Engineering, Northwest Normal University, Key Laboratory of Eco-Environment-Related Polymer Materials Ministry of Education, Lanzhou, PR China. wxm98@163.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of separation science
Periodical, Abbrev.
J.Sep.Sci.
Pub Date Free Form
Oct
Volume
33
Issue
20
Start Page
3239
Other Pages
3244
Notes
LR: 20131121; JID: 101088554; 0 (Polycyclic Hydrocarbons, Aromatic); 059QF0KO0R (Water); 12597-68-1 (Stainless Steel); ppublish
Place of Publication
Germany
ISSN/ISBN
1615-9314; 1615-9306
Accession Number
PMID: 20839236
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1002/jssc.201000287 [doi]
Output Language
Unknown(0)
PMID
20839236
Abstract
A novel mesoporous-coated stainless steel wire microextraction coupled with the HPLC procedure for quantification of four polycyclic aromatic hydrocarbons in water has been developed, based on the sorption of target analytes on a selectively adsorptive fiber and subsequent desorption of analytes directly into HPLC. Phenyl-functionalized mesoporous materials (Ph-SBA-15) were synthesized and coated on the surfaces of a stainless steel wire. Due to the high porosity and large surface area of the Ph-SBA-15, high extraction efficiency is expected. The influence of various parameters on polycyclic aromatic hydrocarbons extraction efficiency were thoroughly studied and optimized (such as the extraction temperature, the extraction time, the desorption time, the stirring rate and the ionic strength of samples). The results showed that each compound for the analysis of real water samples was tested under optimal conditions with the linearity ranging from 1.02x10(-3) to 200 mug/ L and the detection limits were found from 0.32 to 2.44 ng/ L, respectively. The RSD of the new method was smaller than 4.10%.
Descriptors
Chromatography, High Pressure Liquid/economics, Polycyclic Hydrocarbons, Aromatic/analysis, Stainless Steel/chemistry, Time Factors, Water/chemistry
Links
Book Title
Database
Publisher
Data Source
Authors
Wang,X. M., Du,X. Z., Rao,H. H., Lu,X. Q.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in solid matrices using automated cold fiber headspace solid phase microextraction technique 2013 Department of Chemistry, University of Waterloo, Ontario, N2L 3G1, Canada.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
13-Sep
Volume
1307
Issue
Start Page
66
Other Pages
72
Notes
CI: Copyright (c) 2013; JID: 9318488; 0 (Diethylamines); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Soil); 0 (Soil Pollutants); B035PIS86W (diethylamine); OTO: NOTNLM; 2013/06/18 [received]; 2013/07/29 [revised]; 2013/07/30 [accepted]; 2013/08/06 [aheadofp
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 23942478
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.chroma.2013.07.110 [doi]
Output Language
Unknown(0)
PMID
23942478
Abstract
The extraction efficiency of analytes in a cold fiber headspace solid-phase microextraction (CF-HS-SPME) system was investigated both theoretically and experimentally. The system was applied for quantitative extraction of polycyclic aromatic hydrocarbons (PAHs) from solid matrices. In order to achieve better extraction efficiency for PAHs, a method with programmed coating temperature was considered and optimized, leading to higher extraction efficiency for most studied analytes when compared with traditional methods. After optimization of extraction with the programmed coating temperature method, the recoveries were above 90% for the majority of tested compounds from the sand matrix, resulting in exhaustive extraction. Certified reference soil was used to evaluate the cold fiber SPME system. Several organic solvents were used to improve the extraction efficiency. Diethylamine was used successfully to realize the exhaustive extraction for volatile compounds and enhance the recoveries of 60-75% for semi-volatile PAHs. Obtained results indicate that the automated cold fiber extraction is a convenient approach to facilitate high throughput, solventless sample preparation.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Guo,J., Jiang,R., Pawliszyn,J.
Original/Translated Title
URL
Date of Electronic
20130806
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in sediment using solid-phase microextraction with gas chromatography-mass spectrometry 2000 Environmental Research Center Montecatini, Marina di Ravenna, Italy.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatographic science
Periodical, Abbrev.
J.Chromatogr.Sci.
Pub Date Free Form
Feb
Volume
38
Issue
2
Start Page
55
Other Pages
60
Notes
LR: 20061115; JID: 0173225; 0 (Indicators and Reagents); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Solutions); 0 (Water Pollutants, Chemical); ppublish
Place of Publication
UNITED STATES
ISSN/ISBN
0021-9665; 0021-9665
Accession Number
PMID: 10677833
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
10677833
Abstract
Manual solid-phase microextraction (SPME) coupled with gas chromatography-mass spectrometry (GC-MS) is applied for the determination of polycyclic aromatic hydrocarbons (PAHs) from natural matrix through a distilled water medium. Seven of the 16 PAH standards (naphthalene, acenaphthene, fluorene, anthracene, fluoranthene, pyrene, benzo[a]anthracene) are spiked on a marine muddy sediment. The samples, containing PAHs in the range of 10-20 ppm, are then aged at room temperature more than 10 days before analysis. The influence of the matrix, SPME adsorption time, pH, salt content, and SPME adsorption temperature are investigated. The reproducibility of the technique is less than 13% (RDS) for the first 6 considered PAHs and 28% (RDS) for benzo(a)anthracene with a fiber containing a 100-micron poly dimethylsiloxane coating. Linearity extended in the range of 5-50 picograms for PAHs direct injection, 5-70 picograms for PAHs in water, and 1-170 picograms for PAHs in sediment. The detection limit is estimated less than 1 microgram/kg of dry sample for the first 6 considered PAHs in sediment and 1.5 micrograms/kg of dry sample for benzo(a)anthracene using the selected ion monitoring mode in GC-MS. The recoveries of the considered PAHs are evaluated.
Descriptors
Adsorption, Calibration, Gas Chromatography-Mass Spectrometry, Hydrogen-Ion Concentration, Indicators and Reagents, Italy, Polycyclic Hydrocarbons, Aromatic/analysis, Solutions, Temperature, Water Pollutants, Chemical/analysis
Links
Book Title
Database
Publisher
Data Source
Authors
Cam,D., Gagni,S., Meldolesi,L., Galletti,G.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in Persian Gulf and Caspian Sea: gold nanoparticles fiber for a head space solid phase micro extraction 2013 Department of Chemistry, Shahr-e-Rey Branch, Islamic Azad University, P. O. Box 18735-334, Tehran, Iran.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Bulletin of environmental contamination and toxicology
Periodical, Abbrev.
Bull.Environ.Contam.Toxicol.
Pub Date Free Form
Mar
Volume
90
Issue
3
Start Page
291
Other Pages
295
Notes
JID: 0046021; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); 7440-57-5 (Gold); 2012/09/18 [received]; 2012/11/17 [accepted]; 2012/11/25 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1432-0800; 0007-4861
Accession Number
PMID: 23183967
Language
eng
SubFile
Journal Article; IM
DOI
10.1007/s00128-012-0906-2 [doi]
Output Language
Unknown(0)
PMID
23183967
Abstract
A gold nanoparticles modified fused silica fiber was developed and used for the head space solid phase micro-extraction (HS-SPME) of polycyclic aromatic hydrocarbons (PAHs), including naphthalene, anthracene, acenaphthylene, phenanthrene, fluoranthene and pyrene. The effects of different parameters influencing the extraction efficiency including extraction temperature, extraction time, ionic strength, stirring rate and sample volume were examined and optimized. Linear ranges of 1-300 mug L(-1) for naphthalene, 0.5-250 mug L(-1) for anthracene, acenaphthylene and phenanthrene and 0.05-200 mug L(-1) for fluoranthene and pyrene were obtained. Detection limits were in the range of 10-200 mug L(-1). Single fiber repeatability and fiber to fiber reproducibility were less than 2.5 %-6.0 % and 8.5 %-13.6 %, respectively. Seawater samples were analyzed as real samples and good recoveries (91.9 %-105.3 %) were obtained for target analytes.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Karimi,M., Aboufazeli,F., Zhad,H.R., Sadeghi,O., Najafi,E.
Original/Translated Title
URL
Date of Electronic
20121125
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in fresh milk by hollow fiber liquid-phase microextraction-gas chromatography mass spectrometry 2013 Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Johor Bahru, Johor, Malaysia. marsin@kimia.fs.utm.my
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatographic science
Periodical, Abbrev.
J.Chromatogr.Sci.
Pub Date Free Form
Feb
Volume
51
Issue
2
Start Page
112
Other Pages
116
Notes
JID: 0173225; 0 (Environmental Pollutants); 0 (Polycyclic Hydrocarbons, Aromatic); 2012/07/09 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1945-239X; 0021-9665
Accession Number
PMID: 22776739
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/chromsci/bms113 [doi]
Output Language
Unknown(0)
PMID
22776739
Abstract
In this work, a two-phase hollow fiber liquid-phase microextraction (HF-LPME) method combined with gas chromatography-mass spectrometry (GC-MS) is developed to provide a rapid, selective and sensitive analytical method to determine polycyclic aromatic hydrocarbons (PAHs) in fresh milk. The standard addition method is used to construct calibration curves and to determine the residue levels for the target analytes, fluorene, phenanthrene, fluoranthene, pyrene and benzo[a]pyrene, thus eliminating sample pre-treatment steps such as pH adjustment. The HF-LPME method shows dynamic linearity from 5 to 500 microg/L for all target analytes with R(2) ranging from 0.9978 to 0.9999. Under optimized conditions, the established detection limits range from 0.07 to 1.4 microg/L based on a signal-to-noise ratio of 3:1. Average relative recoveries for the determination of PAHs studied at 100 microg/L spiking levels are in the range of 85 to 110%. The relative recoveries are slightly higher than those obtained by conventional solvent extraction, which requires saponification steps for fluorene and phenanthrene, which are more volatile and heat sensitive. The HF-LPME method proves to be simple and rapid, and requires minimal amounts of organic solvent that supports green analysis.
Descriptors
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Database
Publisher
Data Source
Authors
Sanagi,M.M., Loh,S.H., Wan Ibrahim,W.A., Hasan,M.N., Aboul Enein,H.Y.
Original/Translated Title
URL
Date of Electronic
20120709
PMCID
Editors
Determination of polycyclic aromatic hydrocarbons in airborne particulate matter by gas chromatography-triple quadrupole tandem mass spectrometry 2010 University of Almeria, Department of Analytical Chemistry, 04071 Almerea, Spain. agarrido@ual.es
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of AOAC International
Periodical, Abbrev.
J.AOAC Int.
Pub Date Free Form
Jan-Feb
Volume
93
Issue
1
Start Page
284
Other Pages
294
Notes
JID: 9215446; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Polycyclic Hydrocarbons, Aromatic); ppublish
Place of Publication
United States
ISSN/ISBN
1060-3271; 1060-3271
Accession Number
PMID: 20334190
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Validation Studies; IM
DOI
Output Language
Unknown(0)
PMID
20334190
Abstract
An accurate and sensitive method for the identification and the quantification of 24 polycyclic aromatic hydrocarbons (PAHs) in airborne particulate matter has been developed and validated using GC/MS/MS with a triple quadrupole analyzer. Ultrasonic extraction (USE) and pressurized liquid extraction (PLE) were evaluated. PLE was selected because it provided better recoveries and reduced treatment time and use of solvents compared to USE. Cleanup of PLE extracts was not necessary. The accuracy of the optimized method was tested using a standard reference material of urban dust (SRM 1649a). PAH recoveries were between 70 and 99% (except for naphthalene, which was lower than 20%) with RSDs ranging from 2.6 to 15.3%. Linearity in the range 5-500 ng/mL provided R2 values higher than 0.99 for all compounds. LODs for PAHs ranged from 0.001 to 0.435 ng/mL and LOQs ranged from 0.003 to 0.757 ng/mL. The proposed method was applied to the analysis of real samples collected in the city of Almeria, Spain, where some PAHs were found at levels lower than the legislated limit.
Descriptors
Air Pollutants/analysis, Gas Chromatography-Mass Spectrometry/methods/statistics & numerical data, Particulate Matter/analysis, Polycyclic Hydrocarbons, Aromatic/analysis, Spain, Tandem Mass Spectrometry/methods/statistics & numerical data
Links
Book Title
Database
Publisher
Data Source
Authors
Frenich,A. G., Ocana,R. M., Vidal,J. L.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors