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Bacterial Composition of the Human Upper Gastrointestinal Tract Microbiome Is Dynamic and Associated with Genomic Instability in a Barrett's Esophagus Cohort 2015 Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America; Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.; Human Biology, Fred Hutchinson
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
15-Jun
Volume
10
Issue
6
Start Page
e0129055
Other Pages
Notes
LR: 20160610; BioProject/PRJNA270661; GR: K05 CA124911/CA/NCI NIH HHS/United States; GR: K05 CA124911/CA/NCI NIH HHS/United States; GR: P01 CA 91955/CA/NCI NIH HHS/United States; GR: P01 CA091955/CA/NCI NIH HHS/United States; GR: P30 CA015704/CA/NCI NIH H
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 26076489
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; IM
DOI
10.1371/journal.pone.0129055 [doi]
Output Language
Unknown(0)
PMID
26076489
Abstract
BACKGROUND: The incidence of esophageal adenocarcinoma (EAC) has increased nearly five-fold over the last four decades in the United States. Barrett's esophagus, the replacement of the normal squamous epithelial lining with a mucus-secreting columnar epithelium, is the only known precursor to EAC. Like other parts of the gastrointestinal (GI) tract, the esophagus hosts a variety of bacteria and comparisons among published studies suggest bacterial communities in the stomach and esophagus differ. Chronic infection with Helicobacter pylori in the stomach has been inversely associated with development of EAC, but the mechanisms underlying this association remain unclear. METHODOLOGY: The bacterial composition in the upper GI tract was characterized in a subset of participants (n=12) of the Seattle Barrett's Esophagus Research cohort using broad-range 16S PCR and pyrosequencing of biopsy and brush samples collected from squamous esophagus, Barrett's esophagus, stomach corpus and stomach antrum. Three of the individuals were sampled at two separate time points. Prevalence of H. pylori infection and subsequent development of aneuploidy (n=339) and EAC (n=433) was examined in a larger subset of this cohort. RESULTS/SIGNIFICANCE: Within individuals, bacterial communities of the stomach and esophagus showed overlapping community membership. Despite closer proximity, the stomach antrum and corpus communities were less similar than the antrum and esophageal samples. Re-sampling of study participants revealed similar upper GI community membership in two of three cases. In this Barrett's esophagus cohort, Streptococcus and Prevotella species dominate the upper GI and the ratio of these two species is associated with waist-to-hip ratio and hiatal hernia length, two known EAC risk factors in Barrett's esophagus. H. pylori-positive individuals had a significantly decreased incidence of aneuploidy and a non-significant trend toward lower incidence of EAC.
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Database
Publisher
Data Source
Authors
Gall,A., Fero,J., McCoy,C., Claywell,B.C., Sanchez,C.A., Blount,P.L., Li,X., Vaughan,T.L., Matsen,F.A., Reid,B.J., Salama,N.R.
Original/Translated Title
URL
Date of Electronic
20150615
PMCID
PMC4468150
Editors
Crystal structure of methyl 2-hy-droxy-5-[(4-oxo-4,5-di-hydro-1,3-thia-zol-2-yl)amino]benzoate 2015 Chemistry and Environmental Division, Manchester Metropolitan University, Manchester M1 5GD, England ; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.; Department of Chemistry, Tulane University, New Orleans, LA 70118, U
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Crystallographic communications
Periodical, Abbrev.
Acta Crystallogr.E.Crystallogr.Commun.
Pub Date Free Form
9-Apr
Volume
71
Issue
Pt 5
Start Page
o282
Other Pages
3
Notes
LR: 20150524; JID: 101648987; OID: NLM: PMC4420109; OTO: NOTNLM; 2015/05/01 [ecollection]; 2015/03/26 [received]; 2015/03/30 [accepted]; 2015/04/09 [epublish]; epublish
Place of Publication
England
ISSN/ISBN
2056-9890
Accession Number
PMID: 25995905
Language
eng
SubFile
Journal Article
DOI
10.1107/S2056989015006416 [doi]
Output Language
Unknown(0)
PMID
25995905
Abstract
The title compound, C11H10N2O4S, crystallized with two independent mol-ecules (A and B) in the asymmetric unit. They differ primarily in the rotational orientation of the five-membered heterocyclic ring. In mol-ecule A this ring is inclined to the benzene ring by 48.17 (8) degrees , while in mol-ecule B the same dihedral angle is 23.07 (8) degrees . In each mol-ecule there is an intra-molecular O-Hcdots, three dots, centeredO hydrogen bond involving the adjacent hydroxyl group and the ester carbonyl O atom. In the crystal, the A mol-ecules are linked via pairs of N-Hcdots, three dots, centeredN hydrogen bonds, forming inversion dimers. These dimers are linked to the B mol-ecules via N-H..O, C-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredS hydrogen bonds forming corrugated sheets lying parallel to (102).
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Mohamed,S.K., Mague,J.T., Akkurt,M., Abdu-Allah,H.H., Albayati,M.R.
Original/Translated Title
URL
Date of Electronic
20150409
PMCID
PMC4420109
Editors
Paan (pan) and paan (pan) masala should be considered tobacco products 2015 Division of General Internal Medicine, Department of Medicine, University of California, Davis, Sacramento, CA, USA Department of Health Sciences, California State University, East Bay, Hayward, CA, USA.; Institute for Population Health Improvement, Unive
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Dec
Volume
24
Issue
e4
Start Page
e280
Other Pages
4
Notes
CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/; GR: 1-TW-02-005/TW/FIC NIH HHS/United States; GR: U54CA15
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 25335900
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1136/tobaccocontrol-2014-051700 [doi]
Output Language
Unknown(0)
PMID
25335900
Abstract
Two products indigenous to the Indian subcontinent and popular among South Asians globally - paan and paan masala - are inconsistently categorised as tobacco by researchers, clinicians, program planners and policymakers. This article calls for a universally standard classification of these smokeless carcinogenic products as tobacco products and thus, subject to the same public health and clinical protections applied to other forms of tobacco. This recommendation is guided by scientific evidence strongly indicating the common presence of tobacco in paan and paan masala. Inclusion of these two products in population-level surveillance, clinical screening, as well as public health program planning and policy interventions may have considerable impact on preventing and reducing tobacco-related disparities among South Asians around the world.
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Book Title
Database
Publisher
Data Source
Authors
Mukherjea,A., Modayil,M.V., Tong,E.K.
Original/Translated Title
URL
Date of Electronic
20141021
PMCID
Editors
Crystal structure of 1-(1-methyl-1H-imidazol-2-yl)-4-phenyl-1H-1,2,3-triazole dihydrate 2015 University of Innsbruck, Faculty of Chemistry and Pharmacy, Innrain 80, 6020 Innsbruck, Austria.; University of Innsbruck, Faculty of Chemistry and Pharmacy, Innrain 80, 6020 Innsbruck, Austria.; University of Innsbruck, Faculty of Chemistry and Pharmacy,
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Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Crystallographic communications
Periodical, Abbrev.
Acta Crystallogr.E.Crystallogr.Commun.
Pub Date Free Form
14-Nov
Volume
71
Issue
Pt 12
Start Page
o945
Other Pages
6
Notes
LR: 20160214; JID: 101648987; OID: NLM: PMC4719915; OTO: NOTNLM; 2015/12/01 [ecollection]; 2015/10/30 [received]; 2015/11/01 [accepted]; 2015/11/14 [epublish]; epublish
Place of Publication
England
ISSN/ISBN
2056-9890
Accession Number
PMID: 26870543
Language
eng
SubFile
Journal Article
DOI
10.1107/S2056989015020721 [doi]
Output Language
Unknown(0)
PMID
26870543
Abstract
The title compound, C12H11N5.2H2O, which crystallizes as a dihydrate, was obtained by Cu(I)-catalysed azide-alkyne cyclo-addition from 2-azido-1-methyl-imidazole and phenyl-ethyne. The dihedral angles between the central triazole ring (r.m.s. deviation = 0.004 A) and the pendant imidazole (r.m.s. deviation = 0.006 A) and phenyl rings are 12.3 (2) and 2.54 (19) degrees , respectively. In the crystal, the water mol-ecules are connected into [010] chains by O-Hcdots, three dots, centeredO hydrogen bonds, while O-Hcdots, three dots, centeredN hydrogen bonds connect the water mol-ecules to the organic mol-ecules, generating corrugated (100) sheets.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Haslinger,S., Laus,G., Wurst,K., Schottenberger,H.
Original/Translated Title
URL
Date of Electronic
20151114
PMCID
PMC4719915
Editors
Crystal structure of (E)-2-{[(4-anilinophen-yl)imino]-meth-yl}phenol 2015 Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, UP 208 016, India.; National Taras Shevchenko University, Department of Chemistry, Volodymyrska str. 64, 01601 Kyiv, Ukraine.; National Taras Shevchenko University, Department of Chem
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Crystallographic communications
Periodical, Abbrev.
Acta Crystallogr.E.Crystallogr.Commun.
Pub Date Free Form
1-Jan
Volume
71
Issue
Pt 1
Start Page
28
Other Pages
30
Notes
LR: 20150225; JID: 101648987; OID: NLM: PMC4331856; OTO: NOTNLM; 2015/01/01 [ecollection]; 2014/11/21 [received]; 2014/11/30 [accepted]; epublish
Place of Publication
England
ISSN/ISBN
2056-9890
Accession Number
PMID: 25705442
Language
eng
SubFile
Journal Article
DOI
10.1107/S2056989014026309 [doi]
Output Language
Unknown(0)
PMID
25705442
Abstract
The title compound, C19H16N2O, crystallized with two independent mol-ecules (A and B) in the asymmetric unit. There is an intra-molecular O-Hcdots, three dots, centeredN hydrogen bond in each mol-ecule with the phenol ring being inclined to the central benzene ring by 4.93 (14) and 7.12 (14) degrees in mol-ecules A and B, respectively. The conformation of the two mol-ecules differs essentially in the orientation of the terminal amino-phenyl ring with respect to the central benzene ring; this dihedral angle is 50.51 (4) degrees in mol-ecule A and 54.61 (14) degrees in mol-ecule B. The two outer aromatic rings are inclined to one another by 51.39 (14) and 49.88 (14) degrees in mol-ecules A and B, respectively. In the crystal, mol-ecules are connected by N-Hcdots, three dots, centeredO hydrogen bonds generating -A-B-A-B- zigzag chains extending along [010]. The chains are linked via C-Hcdots, three dots, centeredpi inter-actions involving neighbouring A mol-ecules, forming slabs lying parallel to (100).
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Faizi,M.S., Iskenderov,T.S., Sharkina,N.O.
Original/Translated Title
URL
Date of Electronic
20150101
PMCID
PMC4331856
Editors
Twitter chatter about marijuana 2015 Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri. Electronic address: rehgp@psychiatry.wustl.edu.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.; Department of Psychiatry, W
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Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Periodical, Abbrev.
J.Adolesc.Health
Pub Date Free Form
Feb
Volume
56
Issue
2
Start Page
139
Other Pages
145
Notes
LR: 20160202; CI: Copyright (c) 2015; GR: R01 DA032843/DA/NIDA NIH HHS/United States; GR: R01 DA032843/DA/NIDA NIH HHS/United States; GR: R01 DA039455/DA/NIDA NIH HHS/United States; GR: R01 DA039455/DA/NIDA NIH HHS/United States; GR: R01DA031288/DA/NIDA N
Place of Publication
United States
ISSN/ISBN
1879-1972; 1054-139X
Accession Number
PMID: 25620299
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.jadohealth.2014.10.270 [doi]
Output Language
Unknown(0)
PMID
25620299
Abstract
PURPOSE: We sought to examine the sentiment and themes of marijuana-related chatter on Twitter sent by influential Twitter users and to describe the demographics of these Twitter users. METHODS: We assessed the sentiment and themes of a random sample (n = 7,000) of influential marijuana-related tweets (sent from February 5, 20114, to March 5, 2014). Demographics of the users tweeting about marijuana were inferred using a social media analytics company (Demographics Pro for Twitter). RESULTS: Most marijuana-related tweets reflected a positive sentiment toward marijuana use, with pro-marijuana tweets outnumbering anti-marijuana tweets by a factor of greater than 15. The most common theme of pro-marijuana tweets included the Tweeter stating that he/she wants/plans to use marijuana, followed by tweeting about frequent/heavy/or regular marijuana use, and that marijuana has health benefits and/or should be legalized. Tweeters of marijuana-related content were younger and a greater proportion was African-American compared with the Twitter average. CONCLUSIONS: Marijuana Twitter chatter sent by influential Twitter users tends to be pro-marijuana and popular among African-Americans and youth/young adults. Marijuana-related harms may afflict some individuals; therefore, our findings should be used to inform online and offline prevention efforts that work to target individuals who are most at risk for harms associated with marijuana use.
Descriptors
Links
Book Title
Database
Publisher
Society for Adolescent Health and Medicine. Published by Elsevier Inc
Data Source
Authors
Cavazos-Rehg,P.A., Krauss,M., Fisher,S.L., Salyer,P., Grucza,R.A., Bierut,L.J.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4306811
Editors
Association between exposure to secondhand smoke during pregnancy and low birthweight: a narrative review 2015 Department of Applied Health Sciences, College of Nursing, Health, and Human Services, Indiana State University, Terre Haute, Indiana.; Division of Respiratory Therapy, School of Health Professions, Georgia State University, Atlanta, Georgia. oliver2387@b
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Respiratory care
Periodical, Abbrev.
Respir.Care
Pub Date Free Form
Jan
Volume
60
Issue
1
Start Page
135
Other Pages
140
Notes
CI: Copyright (c) 2015; JID: 7510357; 0 (Tobacco Smoke Pollution); OTO: NOTNLM; 2014/07/08 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1943-3654; 0020-1324
Accession Number
PMID: 25006271
Language
eng
SubFile
Journal Article; Review; IM
DOI
10.4187/respcare.02798 [doi]
Output Language
Unknown(0)
PMID
25006271
Abstract
Exposure to secondhand smoke (SHS) during pregnancy may have adverse effects on the mother and infant. This study investigates the association of maternal exposure to SHS with low birthweight (LBW) in infants. Smoking during pregnancy has been linked to multiple complications for both mother and infant. To examine association of LBW and environmental tobacco smoke exposure during pregnancy, we reviewed 20 articles. Articles were accessed using the following electronic databases: CINAHL Plus with full text (EBSCO), PubMed, Embase, and MEDLINE. The findings of this review revealed that maternal exposure to environmental smoke is correlated with LBW in infants as well as numerous other adverse effects. The majority of the studies found negative consequences of SHS on the birthweight of infants born to nonsmoking women. Thus, this review helps to confirm the association between maternal exposure to SHS and LBW in infants.
Descriptors
Links
Book Title
Database
Publisher
by Daedalus Enterprises
Data Source
Authors
Hawsawi,A.M., Bryant,L.O., Goodfellow,L.T.
Original/Translated Title
URL
Date of Electronic
20140708
PMCID
Editors
Study of Lactic Acid Bacteria Community From Raw Milk of Iranian One Humped Camel and Evaluation of Their Probiotic Properties 2015 Department of Food Science and Technology, Ferdowsi University of Mashhad, Mashhad, IR Iran.; Department of Food Science and Technology, Ferdowsi University of Mashhad, Mashhad, IR Iran.; Department of Veterinary Research and Biotechnology, Razi Vaccine a
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Jundishapur journal of microbiology
Periodical, Abbrev.
Jundishapur J.Microbiol.
Pub Date Free Form
31-May
Volume
8
Issue
5
Start Page
e16750
Other Pages
Notes
LR: 20150613; JID: 101515122; OID: NLM: PMC4458354; OTO: NOTNLM; 2015/05 [ecollection]; 2013/12/09 [received]; 2014/04/13 [revised]; 2014/04/22 [accepted]; 2015/05/31 [epublish]; epublish
Place of Publication
Iran
ISSN/ISBN
2008-3645; 2008-3645
Accession Number
PMID: 26060561
Language
eng
SubFile
Journal Article
DOI
10.5812/jjm.8(5)2015.16750 [doi]
Output Language
Unknown(0)
PMID
26060561
Abstract
BACKGROUND: Camel milk is amongst valuable food sources in Iran. On the other hand, due to the presence of probiotic bacteria and bacteriocin producers in camel milk, probiotic bacteria can be isolated and identified from this food product. OBJECTIVES: The objectives of the present research were the isolation and molecular identification of lactic acid bacteria from camel milk and evaluation of their probiotic properties. MATERIALS AND METHODS: A total of ten samples of camel milk were collected from the Golestan province of Iran under aseptic conditions. Bacteria were isolated by culturing the samples on selective medium. Isolates were identified by amplification of the 16S rDNA and Internal Transcribed Spacer (ITS) region between the 16S and 23S rRNA genes by Polymerase Chain Reaction (PCR) and were then screened and grouped by the Amplified Ribosomal DNA Restriction Analysis (ARDRA) method. To evaluate probiotic properties, representative isolates of different ARDRA profiles were analyzed. The antimicrobial activity of Lactic Acid Bacteria (LAB) against Pediococcus pentosaceus, Escherichia coli and Bacillus cereus was examined by the agar diffusion assay. Acid and bile tolerance of isolates were evaluated. RESULTS: A total of 64 isolates were analyzed based on biochemical tests and morphological characteristics. The most frequently isolated LAB was Enterococci. Weissella, Leuconostoc, Lactobacilli and Pediococci were less frequently found. Based on restriction analysis of the ITS, the isolates were grouped into nine different ARDRA patterns that were identified by ribosomal DNA sequencing as P. pentosaceus, Enterococcus faecium strain Y-2, E. faecium strain JZ1-1, E. faecium strain E6, E. durans, E. lactis, Leuconostoc mesenteroides, Lactobacillus casei and Weissella cibaria. The results showed that antimicrobial activity of the tested isolates was remarkable and P. pentosaceus showed the most antibacterial activity. In addition, E. durans, E. lactis, L. casei and P. pentosaceus were selected as probiotic bacteria. CONCLUSIONS: This study revealed the presence of bacteriocin-producing bacteria and probiotic bacteria in camel milk from the Golestan province of Iran.
Descriptors
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Book Title
Database
Publisher
Data Source
Authors
Davati,N., Tabatabaee Yazdi,F., Zibaee,S., Shahidi,F., Edalatian,M.R.
Original/Translated Title
URL
Date of Electronic
20150531
PMCID
PMC4458354
Editors
Exploration of metal-organic framework MOF-177 coated fibers for headspace solid-phase microextraction of polychlorinated biphenyls and polycyclic aromatic hydrocarbons 2015 Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Guangdong Provincial Public Laboratory of Analysis and Testing Technology, Guangdong Institute of Analysis, Guangzhou 510070, PR China. Electronic address: ghwangvip@163.com.;
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Talanta
Periodical, Abbrev.
Talanta
Pub Date Free Form
1-Nov
Volume
144
Issue
Start Page
369
Other Pages
374
Notes
CI: Copyright (c) 2015; JID: 2984816R; 0 (Adhesives); 0 (Organometallic Compounds); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Water Pollutants, Chemical); 059QF0KO0R (Water); DFC2HB4I0K (Polychlorinated Biphenyls); OTO: NOTNLM; 2015/04/29 [received]; 2015
Place of Publication
Netherlands
ISSN/ISBN
1873-3573; 0039-9140
Accession Number
PMID: 26452835
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.talanta.2015.06.058 [doi]
Output Language
Unknown(0)
PMID
26452835
Abstract
Metal-organic frameworks (MOFs) have received much attention in analytical science for their large langmuir surface and high thermostability. Herein MOF-177-coated solid-phase micro-extraction (SPME) fibers were fabricated on etched stainless steel by an adhensive method, and applied to the enrichment of polychlorinated biphenyls (PCB01, PCB05, PCB29, PCB47, PCB98, PCB154, PCB171, PCB201) and polycyclic aromatic hydrocarbons (ANY, ANA, FLU, PHE, ANT, FLT, PYR) from environmental water samples. Several parameters affecting the extraction efficiency were optimized prior to the gas chromatography-mass spectrometry analysis, including extraction temperature and time, desorption time, stirring rate and salt addition. The results indicated that the coated fiber gave low detection limits (0.69-4.42 ng L(-1)) and good repeatability with the RSD ranging from 1.47% to 8.67% for PCBs and PAHs. The recoveries were between 81.8% and 113% with the spiked level of 10 ng L(-1) for the real water samples. Besides, the MOF-177 coated fiber was stable enough over 100 extraction cycles and the RSD for fiber-to- fiber reproducibility was less than 9.82% during the experiment.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Wang,G., Lei,Y., Song,H.
Original/Translated Title
URL
Date of Electronic
20150623
PMCID
Editors
In reply 2015
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Deutsches Arzteblatt international
Periodical, Abbrev.
Dtsch.Arztebl Int.
Pub Date Free Form
27-Mar
Volume
112
Issue
13
Start Page
221
Other Pages
Notes
LR: 20151111; JID: 101475967; CON: Dtsch Arztebl Int. 2014 Oct 3;111(40):674-9. PMID: 25346357; CON: Dtsch Arztebl Int. 2015 Mar 27;112(13):221. PMID: 25869342; OID: NLM: PMC4453467; ppublish
Place of Publication
Germany
ISSN/ISBN
1866-0452; 1866-0452
Accession Number
PMID: 25869343
Language
eng
SubFile
Comment; Letter; IM
DOI
10.3238/arztebl.2015.0221b [doi]
Output Language
Unknown(0)
PMID
25869343
Abstract
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
von Rappard,J.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4453467
Editors