WTS database

Title	Pub Year	Author	SearchLink Sort descending
Youth tobacco cessation: quitting intentions and past-year quit attempts	2014	Office of Science, Center for Tobacco Products, Food and Drug Administration, Rockville, Maryland. Electronic address: cindy.tworek@fda.hhs.gov.; Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Aug Volume 47 Issue 2 Suppl 1 Start Page S15 Other Pages 27 Notes CI: Published by Elsevier Inc.; JID: 8704773; 2013/12/11 [received]; 2014/05/01 [revised]; 2014/05/05 [accepted]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 25044192 Language eng SubFile Journal Article; IM DOI 10.1016/j.amepre.2014.05.009 [doi] Output Language Unknown(0) PMID 25044192 Abstract BACKGROUND: Despite declining use of conventional tobacco products, youth use of non-cigarette tobacco has become prevalent; however, quitting behaviors remain largely unexplored. PURPOSE: To examine nationally representative data on quit intentions and past-year attempts to quit all tobacco use among current youth tobacco users. METHODS: In 2013, data were analyzed from the 2012 National Youth Tobacco Survey (NYTS). Weighted prevalence estimates of quit intentions and past-year quit attempts for current youth tobacco users are presented. RESULTS: Prevalence of quit intentions and past-year attempts to quit all tobacco use were 52.8% and 51.5%, respectively, among current youth tobacco users. Among non-mutually exclusive groups, current cigarette smokers had the highest prevalence of quit intentions (56.8%) and past-year quit attempts (52.5%), whereas current hookah users had the lowest prevalence of quit intentions (41.5%) and past-year quit attempts (43.7%). Quit intentions among black, non-Hispanics (65.0%) and Hispanics (60.4%) were significantly higher versus white, non-Hispanics (47.5%). Youth reporting parental advice against tobacco had significantly higher prevalence of quit intentions (56.7%) and past-year quit attempts (55.0%) than those not reporting parental advice. Youth who agreed all tobacco products are dangerous (58.5%) had significantly higher prevalence of quit intentions than those who disagreed (37.0%). CONCLUSIONS: Continued efforts are needed to better understand youth motivation for quitting all tobacco products. Public health messaging about the dangers of all tobacco and cessation efforts should be aimed at the full range of tobacco products, not just cigarettes, and tailored to meet the needs of youth polytobacco users. Descriptors Links Book Title Database Publisher Data Source Authors Tworek,C., Schauer,G.L., Wu,C.C., Malarcher,A.M., Jackson,K.J., Hoffman,A.C. Original/Translated Title URL Date of Electronic PMCID Editors
Cigar smoking among U.S. students: reported use after adding brands to survey items	2014	Office of Science, Center for Tobacco Products, Food and Drug Administration, Rockville, Maryland. Electronic address: catherine.corey@fda.hhs.gov.; Division of Epidemiology and Biostatistics, School of Public Health, Georgia State University, Atlanta, Ge	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Aug Volume 47 Issue 2 Suppl 1 Start Page S28 Other Pages 35 Notes LR: 20151026; CI: Published by Elsevier Inc.; GR: CC999999/Intramural CDC HHS/United States; JID: 8704773; HHSPA709984; OID: NLM: HHSPA709984; OID: NLM: PMC4521384; 2013/11/28 [received]; 2014/05/01 [revised]; 2014/05/02 [accepted]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 25044193 Language eng SubFile Journal Article; IM DOI 10.1016/j.amepre.2014.05.004 [doi] Output Language Unknown(0) PMID 25044193 Abstract BACKGROUND: Among U.S. youth overall, cigars are the most commonly used tobacco product after cigarettes. However, youth who identify their products by brand names, not general terms like "cigar," may underreport use. PURPOSE: To examine changes in reported cigar (cigar, cigarillo, or little cigar) smoking among students following inclusion of cigar brand examples on the National Youth Tobacco Survey (NYTS). METHODS: Data from the 2011 and 2012 NYTS and National Survey on Drug Use and Health (NSDUH) were analyzed in 2013 to estimate ever and current cigar smoking, overall and by race/ethnicity. The 2012 NYTS included cigar brand examples (Black and Mild, Swisher Sweets, Dutch Masters, White Owl, Phillies Blunt) in the survey instructions and ever use question, but the 2011 NYTS and 2011 and 2012 NSDUH did not. RESULTS: NYTS ever cigar smoking was higher in 2012 (27.8%) than 2011 (19.5%) among black students overall. Current cigar smoking was 60%-70% higher among black females and students aged >/= 17 years, in 2012 than 2011. For black females, current cigar smoking (11.5%) was two times greater than that of white females (4.3%) in 2012, whereas the prevalence among these subgroups was comparable in 2011. Similar changes were not observed among these subgroups in the 2011-2012 NSDUH. CONCLUSIONS: This study highlights the high burden of cigar use among U.S. youth and suggests that NYTS ascertainment of cigar smoking may have improved by including brands. Disparities in cigar smoking need to be addressed to prevent and reduce all youth tobacco use. Descriptors Links Book Title Database Publisher Data Source Authors Corey,C.G., Dube,S.R., Ambrose,B.K., King,B.A., Apelberg,B.J., Husten,C.G. Original/Translated Title URL Date of Electronic PMCID PMC4521384 Editors
Awareness and use of non-conventional tobacco products among U.S. students, 2012	2014	Office of Science, Center for Tobacco Products, Food and Drug Administration, Rockville, Maryland. Electronic address: baoguang.wang@fda.hhs.gov.; Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atla	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Aug Volume 47 Issue 2 Suppl 1 Start Page S36 Other Pages 52 Notes LR: 20151026; CI: Published by Elsevier Inc.; GR: CC999999/Intramural CDC HHS/United States; JID: 8704773; HHSPA709991; OID: NLM: HHSPA709991; OID: NLM: PMC4519346; 2013/11/28 [received]; 2014/04/30 [revised]; 2014/05/01 [accepted]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 25044194 Language eng SubFile Journal Article; IM DOI 10.1016/j.amepre.2014.05.003 [doi] Output Language Unknown(0) PMID 25044194 Abstract BACKGROUND: Increasing diversity of the tobacco product landscape, including electronic cigarettes (e-cigarettes), hookah, snus, and dissolvable tobacco products (dissolvables), raises concerns about the public health impact of these non-conventional tobacco products among youth. PURPOSE: This study assessed awareness, ever use, and current use of non-conventional tobacco products among U.S. students in 2012, overall and by demographic and tobacco use characteristics. METHODS: Data from the 2012 National Youth Tobacco Survey, a nationally representative survey of U.S. middle and high school students, were analyzed in 2013. Prevalence of awareness, ever use, and current use of e-cigarettes, hookah, snus, and dissolvables were calculated overall and by sex, school level, race/ethnicity, and conventional tobacco product use, including cigarettes, cigars, or smokeless tobacco (chewing tobacco, snuff, or dip). RESULTS: Overall, 50.3% of students were aware of e-cigarettes; prevalence of ever and current use of e-cigarettes was 6.8% and 2.1%, respectively. Awareness of hookah was 41.2% among all students, and that of ever and current use were 8.9% and 3.6%, respectively. Overall awareness; ever; and current use of snus (32%, 5.3%, 1.7%, respectively) and dissolvables (19.3%, 2.0%, 0.7%, respectively) were generally lower than those of e-cigarettes or hookah. Conventional tobacco product users were more likely to be aware of and to use non-conventional tobacco products. CONCLUSIONS: Many U.S. students are aware of and use non-conventional tobacco products. Evidence-based interventions should be implemented to prevent and reduce all tobacco use among youth. Descriptors Links Book Title Database Publisher Data Source Authors Wang,B., King,B.A., Corey,C.G., Arrazola,R.A., Johnson,S.E. Original/Translated Title URL Date of Electronic PMCID PMC4519346 Editors
Symptoms of tobacco dependence among middle and high school tobacco users: results from the 2012 National Youth Tobacco Survey	2014	Office of Science Rockville, Maryland. Electronic address: benjamin.apelberg@fda.hhs.gov.; Office of Science Rockville, Maryland.; Office of Science Rockville, Maryland.; Office of Science Rockville, Maryland.; Office of the Center Director, Center for To	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Aug Volume 47 Issue 2 Suppl 1 Start Page S4 Other Pages 14 Notes LR: 20160221; CI: Published by Elsevier Inc.; GR: CC999999/Intramural CDC HHS/United States; JID: 8704773; HHSPA726039; OID: NLM: HHSPA726039; OID: NLM: PMC4624110; 2013/11/28 [received]; 2014/04/24 [revised]; 2014/04/29 [accepted]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 25044195 Language eng SubFile Journal Article; IM DOI 10.1016/j.amepre.2014.04.013 [doi] Output Language Unknown(0) PMID 25044195 Abstract BACKGROUND: A growing body of evidence suggests that tobacco dependence symptoms can occur soon after smoking onset and with low levels of use. However, limited data are available nationally and among non-cigarette tobacco users. PURPOSE: To examine the prevalence and determinants of tobacco dependence symptoms among adolescent tobacco users in the 2012 National Youth Tobacco Survey, a nationally representative, school-based survey of U.S. middle and high school students. METHODS: Multivariate logistic regression was used to identify independent predictors of dependence symptoms among current users (i.e., past 30-day use) of cigarettes, cigars, or smokeless tobacco. Analyses were conducted in 2013 using SAS-callable SUDAAN, version 11 to account for the complex survey design. RESULTS: Prevalence of tobacco dependence symptoms ranged from 20.8% (95% CI=18.6, 23.1) of current tobacco users reporting wanting to use tobacco within 30 minutes of waking to 41.9% (95% CI=39.3, 44.5) reporting recent strong cravings. Reporting of dependence symptoms was most consistently associated with polytobacco use, higher frequency of use, earlier initiation age, and female gender. A 2-4-fold increase in the odds of symptom reporting was found in adolescents using tobacco products on as few as 3-5 days compared to those who only used it for 1-2 of the past 30 days. CONCLUSIONS: A substantial proportion of U.S. adolescent tobacco users, including those with low levels of use, report symptoms of tobacco dependence. These findings demonstrate the need for full implementation of evidence-based strategies to prevent both experimentation and progression to regular tobacco use among youth. Descriptors Links Book Title Database Publisher Data Source Authors Apelberg,B.J., Corey,C.G., Hoffman,A.C., Schroeder,M.J., Husten,C.G., Caraballo,R.S., Backinger,C.L. Original/Translated Title URL Date of Electronic PMCID PMC4624110 Editors
Self-reported exposure to tobacco warning labels among U.S. middle and high school students	2014	Office of Science, Center for Tobacco Products, Food and Drug Administration, Rockville. Electronic address: sarah.johnson@fda.hhs.gov.; Office of Extramural Research, NIH, Bethesda, Maryland.; Office of Science, Center for Tobacco Products, Food and Drug	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Aug Volume 47 Issue 2 Suppl 1 Start Page S69 Other Pages 75 Notes CI: Published by Elsevier Inc.; JID: 8704773; 2013/11/28 [received]; 2014/04/24 [revised]; 2014/05/02 [accepted]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 25044198 Language eng SubFile Journal Article; IM DOI 10.1016/j.amepre.2014.05.005 [doi] Output Language Unknown(0) PMID 25044198 Abstract BACKGROUND: Warning labels on tobacco products are a means to communicate information about the negative health effects of tobacco use to current and potential users. Most tobacco use begins in early adolescence, making it particularly important to understand the degree to which warning labels reach adolescents. PURPOSE: To examine the extent to which youth report (1) seeing the current warnings on cigarettes and smokeless tobacco (SLT) products in the U.S. and (2) that seeing warnings makes them think about the health risks associated with tobacco use. METHODS: Exposure to warning labels on cigarettes and SLT, as well as the degree to which adolescents report thinking about health risks in response to warnings, was examined among U.S. middle and high school students using data from the 2012 National Youth Tobacco Survey (NYTS) and analyzed in 2013. RESULTS: Current data suggest that less than half of adolescents who saw a cigarette pack (46.9%) or SLT product (40.3%) reported seeing the warning label "most of the time" or "always." Among adolescents who reported seeing a warning, less than one third reported that cigarette (30.4%) or SLT (25.2%) warning labels made them think about health risks "a lot." These rates were even lower among current tobacco users ( Descriptors Links Book Title Database Publisher Data Source Authors Johnson,S.E., Wu,C.C., Coleman,B.N., Choiniere,C.J. Original/Translated Title URL Date of Electronic PMCID Editors
Youth curiosity about cigarettes, smokeless tobacco, and cigars: prevalence and associations with advertising	2014	Office of Science, Center for Tobacco Products, Food and Drug Administration, Rockville. Electronic address: david.portnoy@fda.hhs.gov.; Office of Extramural Research, NIH, Bethesda, Maryland.; Office of Science, Center for Tobacco Products, Food and Drug	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Preventive Medicine Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Aug Volume 47 Issue 2 Suppl 1 Start Page S76 Other Pages 86 Notes CI: Published by Elsevier Inc.; JID: 8704773; 2013/12/10 [received]; 2014/04/24 [revised]; 2014/04/29 [accepted]; ppublish Place of Publication Netherlands ISSN/ISBN 1873-2607; 0749-3797 Accession Number PMID: 25044199 Language eng SubFile Journal Article; IM DOI 10.1016/j.amepre.2014.04.012 [doi] Output Language Unknown(0) PMID 25044199 Abstract BACKGROUND: Curiosity about cigarettes is a reliable predictor of susceptibility to smoking and established use among youth. Related research has been limited to cigarettes, and lacks national-level estimates. Factors associated with curiosity about tobacco products, such as advertising, have been postulated but rarely tested. PURPOSE: To describe the prevalence of curiosity about cigarettes, smokeless tobacco, and cigars among youth and explore the association between curiosity and self-reported tobacco advertising exposure. METHODS: Data from the 2012 National Youth Tobacco Survey, a nationally representative survey of 24,658 students, were used. In 2013, estimates weighted to the national youth school population were calculated for curiosity about cigarettes, smokeless tobacco, and cigars among never users of any tobacco product. Associations between tobacco advertising and curiosity were explored using multivariable regressions. RESULTS: Curiosity about cigarettes (28.8%); cigars (19.5%); and smokeless tobacco (9.7%) was found, and many youth were curious about more than one product. Exposure to point-of-sale advertising (e.g., OR=1.35, 95% CI=1.19, 1.54 for cigarette curiosity); tobacco company communications (e.g., OR=1.70, 95% CI=1.38, 2.09 for cigarette curiosity); and tobacco products, as well as viewing tobacco use in TV/movies (e.g., OR=1.37, 95% CI=1.20, 1.58 for cigarette curiosity) were associated with curiosity about each examined tobacco product. CONCLUSIONS: Despite decreasing use of tobacco products, youth remain curious about them. Curiosity is associated with various forms of tobacco advertising. These findings suggest the importance of measuring curiosity as an early warning signal for potential future tobacco use and evaluating continued efforts to limit exposure to tobacco marketing among youth. Descriptors Links Book Title Database Publisher Data Source Authors Portnoy,D.B., Wu,C.C., Tworek,C., Chen,J., Borek,N. Original/Translated Title URL Date of Electronic PMCID Editors
Alcohol and the risk of Barrett's esophagus: a pooled analysis from the International BEACON Consortium	2014	1] Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA [2] Cancer Control Group, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Division of Cancer Epid	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The American Journal of Gastroenterology Periodical, Abbrev. Am.J.Gastroenterol. Pub Date Free Form Oct Volume 109 Issue 10 Start Page 1586 Other Pages 1594 Notes LR: 20160610; GR: 1R21DK077742/DK/NIDDK NIH HHS/United States; GR: K05 CA124911/CA/NCI NIH HHS/United States; GR: K05 CA124911/CA/NCI NIH HHS/United States; GR: K23DK59311/DK/NIDDK NIH HHS/United States; GR: R01 CA 001833/CA/NCI NIH HHS/United States; GR: Place of Publication United States ISSN/ISBN 1572-0241; 0002-9270 Accession Number PMID: 25047401 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; IM DOI 10.1038/ajg.2014.206 [doi] Output Language Unknown(0) PMID 25047401 Abstract OBJECTIVES: Results from studies examining the association between alcohol consumption and the risk of Barrett's esophagus have been inconsistent. We assessed the risk of Barrett's esophagus associated with total and beverage-specific alcohol consumption by pooling individual participant data from five case-control studies participating in the international Barrett's and Esophageal Adenocarcinoma Consortium. METHODS: For analysis, there were 1,282 population-based controls, 1,418 controls with gastroesophageal reflux disease (GERD), and 1,169 patients with Barrett's esophagus (cases). We estimated study-specific odds ratios (ORs) and 95% confidence intervals (95% CI) using multivariable logistic regression models adjusted for age, sex, body mass index (BMI), education, smoking status, and GERD symptoms. Summary risk estimates were obtained by random-effects models. We also examined potential effect modification by sex, BMI, GERD symptoms, and cigarette smoking. RESULTS: For comparisons with population-based controls, although there was a borderline statistically significant inverse association between any alcohol consumption and the risk of Barrett's esophagus (any vs. none, summary OR=0.77, 95% CI=0.60-1.00), risk did not decrease in a dose-response manner (Ptrend=0.72). Among alcohol types, wine was associated with a moderately reduced risk of Barrett's esophagus (any vs. none, OR=0.71, 95% CI=0.52-0.98); however, there was no consistent dose-response relationship (Ptrend=0.21). We found no association with alcohol consumption when cases were compared with GERD controls. Similar associations were observed across all strata of BMI, GERD symptoms, and cigarette smoking. CONCLUSIONS: Consistent with findings for esophageal adenocarcinoma, we found no evidence that alcohol consumption increases the risk of Barrett's esophagus. Descriptors Links Book Title Database Publisher Data Source Authors Thrift,A.P., Cook,M.B., Vaughan,T.L., Anderson,L.A., Murray,L.J., Whiteman,D.C., Shaheen,N.J., Corley,D.A. Original/Translated Title URL Date of Electronic 20140722 PMCID PMC4189971 Editors
How popular is waterpipe tobacco smoking? Findings from internet search queries	2015	Department of Health Services Policy and Management, Arnold School of Public Health University of South Carolina, Columbia, South Carolina, USA.; Department of Health Promotion, Education, and Behavior, Arnold School of Public Health University of South C	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Sep Volume 24 Issue 5 Start Page 509 Other Pages 513 Notes LR: 20150823; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: R01 DA035160/DA/NIDA NIH HHS/United States; GR: R Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 25052859 Language eng SubFile Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1136/tobaccocontrol-2014-051675 [doi] Output Language Unknown(0) PMID 25052859 Abstract OBJECTIVES: Waterpipe tobacco smoking (WTS), a traditional tobacco consumption practice in the Middle East, is gaining popularity worldwide. Estimates of population-level interest in WTS over time are not documented. We assessed the popularity of WTS using World Wide Web search query results across four English-speaking countries. METHODS: We analysed trends in Google search queries related to WTS, comparing these trends with those for electronic cigarettes between 2004 and 2013 in Australia, Canada, the UK and the USA. Weekly search volumes were reported as percentages relative to the week with the highest volume of searches. RESULTS: Web-based searches for WTS have increased steadily since 2004 in all four countries. Search volume for WTS was higher than for e-cigarettes in three of the four nations, with the highest volume in the USA. Online searches were primarily targeted at WTS products for home use, followed by searches for WTS cafes/lounges. CONCLUSIONS: Online demand for information on WTS-related products and venues is large and increasing. Given the rise in WTS popularity, increasing evidence of exposure-related harms, and relatively lax government regulation, WTS is a serious public health concern and could reach epidemic levels in Western societies. Descriptors Links Book Title Database Publisher Data Source Authors Salloum,R.G., Osman,A., Maziak,W., Thrasher,J.F. Original/Translated Title URL Date of Electronic 20140722 PMCID PMC4420726 Editors
Promoting cessation resources through cigarette package warning labels: a longitudinal survey with adult smokers in Canada, Australia and Mexico	2015	University of South Carolina, Columbia, South Carolina, USA National Institute of Public Health, Cuernavaca, Mexico.; University of South Carolina, Columbia, South Carolina, USA.; University of Stirling, Scotland, UK.; University of Waterloo, Waterloo, Ca	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Mar Volume 24 Issue e1 Start Page e23 Other Pages 31 Notes LR: 20151215; CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.; GR: MR/K023195/1/Medical Research Council/United King Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 25052860 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; IM DOI 10.1136/tobaccocontrol-2014-051589 [doi] Output Language Unknown(0) PMID 25052860 Abstract INTRODUCTION: Health warning labels (HWLs) on tobacco packaging can be used to provide smoking cessation information, but the impact of this information is not well understood. METHODS: Online consumer panels of adult smokers from Canada, Australia and Mexico were surveyed in September 2012, January 2013 and May 2013; replenishment was used to maintain sample sizes of 1000 participants in each country at each wave. Country-stratified logistic Generalised Estimating Equation (GEE) models were estimated to assess correlates of citing HWLs as a source of information on quitlines and cessation websites. GEE models also regressed having called the quitline, and having visited a cessation website, on awareness of these resources because of HWLs. RESULTS: At baseline, citing HWLs as a source of information about quitlines was highest in Canada, followed by Australia and Mexico (33%, 19% and 16%, respectively). Significant increases over time were only evident in Australia and Mexico. In all countries, citing HWLs as a source of quitline information was significantly associated with self-report of having called a quitline. At baseline, citing HWLs as a source of information about cessation websites was higher in Canada than in Australia (14% and 6%, respectively; Mexico was excluded because HWLs do not include website information), but no significant changes over time were found for either country. Citing HWLs as a source of information about cessation websites was significantly associated with having visited a website in both Canada and Australia. CONCLUSIONS: HWLs are an important source of cessation information. Descriptors Links Book Title Database Publisher Data Source Authors Thrasher,J.F., Osman,A., Moodie,C., Hammond,D., Bansal-Travers,M., Cummings,K.M., Borland,R., Yong,H.H., Hardin,J. Original/Translated Title URL Date of Electronic 20140722 PMCID PMC4368699 Editors
Comparative evaluation of genotoxicity by micronucleus assay in the buccal mucosa over comet assay in peripheral blood in oral precancer and cancer patients	2014	Molecular and Human Genetics Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Kolkata 700032, India and Department of Oral Pathology, Dr R. Ahmed Dental College and Hospital, Kolkata 700014, India.; Molecular and Human Geneti	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Mutagenesis Periodical, Abbrev. Mutagenesis Pub Date Free Form Sep Volume 29 Issue 5 Start Page 325 Other Pages 334 Notes CI: (c) The Author 2014; JID: 8707812; 2014/07/22 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1464-3804; 0267-8357 Accession Number PMID: 25053835 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/mutage/geu023 [doi] Output Language Unknown(0) PMID 25053835 Abstract Early detection and quantification of DNA damage in oral premalignancy or malignancy may help in management of the disease and improve survival rates. The comet assay has been successfully utilised to detect DNA damage in oral premalignant or malignancy. However, due to the invasive nature of collecting blood, it may be painful for many unwilling patients. This study compares the micronucleus (MN) assay in oral buccal mucosa cells with the comet assay in peripheral blood cells in a subset of oral habit-induced precancer and cancer patients. For this, MN assay of exfoliated epithelial cells was compared with comet assay of peripheral blood leucocytes among 260 participants, including those with oral lichen planus (OLP; n = 52), leukoplakia (LPK; n = 51), oral submucous fibrosis (OSF; n = 51), oral squamous cell carcinoma (OSCC; n = 54) and normal volunteers (n = 52). Among the precancer groups, LPK patients showed significantly higher levels of DNA damage as reflected by both comet tail length (P cigarette + khaini > cigarette smokers > areca + khaini > areca. There was no significant difference in the comet length and MNi frequency between males and females who had oral chewing habits. An overall significant correlation was observed between MNi frequency and comet tail length with r = 0.844 and P Descriptors Links Book Title Database Publisher . Published by Oxford University Press on behalf of the UK Environmental Mutagen Society Data Source Authors Katarkar,A., Mukherjee,S., Khan,M.H., Ray,J.G., Chaudhuri,K. Original/Translated Title URL Date of Electronic 20140722 PMCID Editors

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