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Quantitative ultrasound and bone mineral density are equally strongly associated with risk factors for osteoporosis 2001 Osteoporosis Screening and Research Unit, Guy's Hospital, London, United Kingdom.
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Journal Article
Periodical, Full
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Periodical, Abbrev.
J.Bone Miner.Res.
Pub Date Free Form
Feb
Volume
16
Issue
2
Start Page
406
Other Pages
416
Notes
LR: 20071115; JID: 8610640; ppublish
Place of Publication
United States
ISSN/ISBN
0884-0431; 0884-0431
Accession Number
PMID: 11204441
Language
eng
SubFile
Journal Article; IM
DOI
10.1359/jbmr.2001.16.2.406 [doi]
Output Language
Unknown(0)
PMID
11204441
Abstract
Because resources do not allow all women to be screened for osteoporosis, clinical risk factors are often used to identify those individuals at increased risk of fracture who are then assessed by bone densitometry. The aim of this study was to compare calcaneal quantitative ultrasound (QUS) and axial bone mineral density (BMD) T and Z scores in a large group of women, some with no clinical risk factors and others with one or more risk factors for osteoporosis. The study population consisted of 1115 pre- and postmenopausal women. A subgroup of 530 women was used to construct reference data for calculating T and Z scores. A total of 786 women was found to have one or more of the following risk factors: (i) atraumatic fracture since the age of 25 years, (ii) report of X-ray osteopenia, (iii) predisposing medical condition or use of therapy known to affect bone metabolism, (iv) premature menopause before the age of 45 years or a history of amenorrhea of longer than 6 months duration, (v) family history of osteoporosis, (vi) body mass index (BMI) <20 kg/m2, and (vii) current smoking habit. Calcaneal broadband ultrasound attenuation (BUA) and speed of sound (SOS) measurements were performed on a Hologic Sahara and a DTUone and BMD was measured at the spine and hip using dual-energy X-ray absorptiometry (DXA). The Z score decrements associated with the seven risk factors calculated using multivariate regression analysis were similar for QUS and BMD measurements. Z score decrements (mean of BMD and QUS measurements combined) associated with a history of atraumatic fracture (-0.67), X-ray osteopenia (-0.36), a family history of osteoporosis (-0.23), and a low BMI (-0.53) were all statistically significant compared with women with no risk factors. Z score decrements associated with a medical condition or use of therapy known to affect bone metabolism, a premature menopause or prolonged amenorrhea, or those who were current smokers were not significantly different from zero. As the number of risk factors present in each individual increased, the mean Z score decrements became more negative, increasing from -0.28 for women with one risk factor to -1.19 for those with four or more risk factors. QUS and BMD measurements yielded similar mean Z scores for women with one, two, three, or more than four risk factors. Using the World Health Organization (WHO) criteria to diagnose osteoporosis for BMD measurements and revised diagnostic criteria for QUS, approximately one-third of postmenopausal women aged 50+ years with clinical risk factors were classified as osteoporotic compared with only 12% of women without clinical risk factors. Over two-thirds of postmenopausal women with risk factors were classified as osteopenic or osteoporotic and approximately 28% were classified as normal. The proportion of women classified into each diagnostic category was similar for BMD and QUS. In conclusion, clinical risk factors for osteoporosis affected calcaneal BUA and SOS Z score measurements to the same extent as axial BMD Z score measurements. Provided revised diagnostic criteria are adopted for QUS, similar proportions of postmenopausal women are identified as osteopenic or osteoporotic as with BMD.
Descriptors
Absorptiometry, Photon, Adult, Bone Density, Humans, Male, Middle Aged, Osteoporosis/physiopathology/ultrasonography, Prevalence, Risk Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Frost,M. L., Blake,G. M., Fogelman,I.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity 2014 Microbiology Institute, Virology Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. davisf@micro.ufrj.br.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Parasites & vectors
Periodical, Abbrev.
Parasit.Vectors
Pub Date Free Form
28-Mar
Volume
7
Issue
Start Page
130
Other Pages
3305-7-130
Notes
LR: 20150514; JID: 101462774; 0 (Antioxidants); 0 (Antiviral Agents); 0 (Glycosides); 9IKM0I5T1E (Quercetin); OID: NLM: PMC3973022; 2014/01/20 [received]; 2014/03/12 [accepted]; 2014/03/28 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1756-3305; 1756-3305
Accession Number
PMID: 24678592
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1756-3305-7-130 [doi]
Output Language
Unknown(0)
PMID
24678592
Abstract
BACKGROUND: The arthropod-borne Mayaro virus (MAYV) causes 'Mayaro fever', a disease of medical significance, primarily affecting individuals in permanent contact with forested areas in tropical South America. Recently, MAYV has attracted attention due to its likely urbanization. Currently, there are no licensed drugs against most mosquito-transmitted viruses. Here, we investigated the in vitro anti-MAYV activity of the flavonoids quercetin and its derivatives from the Brazilian shrub Bauhinia longifolia (Bong.) Steud. METHODS: Flavonoids were purified by chromatographic fractionation from leaf extracts of B. longifolia and chemically identified as quercetin and quercetin glycosides using spectroscopic techniques. Cytotoxicity of purified flavonoids and of EtOAc- and n-BuOH-containing flavonoid mixtures was measured by the dye-uptake assay while their antiviral activity was evaluated by a virus yield inhibition assay. RESULTS: The following flavonoids were purified from B. longifolia leaves: non-glycosylated quercetin and its glycosides guaijaverin, quercitrin, isoquercitrin, and hyperin. EtOAc and n-BuOH fractions containing these flavonoids demonstrated the highest antiviral activity of all tested substances, while quercetin had the highest antiviral activity amongst purified flavonoids. Quercetin, EtOAc, or n-BuOH fractions inhibited MAYV production by more than 90% at 25 mug/mL, displaying a stronger antiviral effect than the licensed antiviral ribavirin. A mixture of the isomers isoquercitrin and hyperin had a modest antiviral effect (IC90 = 104.9), while guaijaverin and quercitrin did not show significant antiviral activity. CONCLUSIONS: B. longifolia is a good source of flavonoids with anti-Mayaro virus activity. This is the first report of the activity of quercetin and its derivatives against an alphavirus.
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Database
Publisher
Data Source
Authors
dos Santos,A.E., Kuster,R.M., Yamamoto,K.A., Salles,T.S., Campos,R., de Meneses,M.D., Soares,M.R., Ferreira,D.
Original/Translated Title
URL
Date of Electronic
20140328
PMCID
PMC3973022
Editors
Quinacrine inhibits Candida albicans growth and filamentation at neutral pH 2014 Section of Infectious Diseases, New Mexico Veterans Health Care System, Albuquerque, New Mexico, USA.; Section of Infectious Diseases, New Mexico Veterans Health Care System, Albuquerque, New Mexico, USA Division of Infectious Diseases, University of New
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
Dec
Volume
58
Issue
12
Start Page
7501
Other Pages
7509
Notes
LR: 20151029; CI: Copyright (c) 2014; GR: K12 GM088021/GM/NIGMS NIH HHS/United States; JID: 0315061; 0 (Antifungal Agents); 0 (Antiprotozoal Agents); 0 (Drug Combinations); 0 (Echinocandins); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); F0XDI6ZL
Place of Publication
United States
ISSN/ISBN
1098-6596; 0066-4804
Accession Number
PMID: 25288082
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; IM
DOI
10.1128/AAC.03083-14 [doi]
Output Language
Unknown(0)
PMID
25288082
Abstract
Candida albicans is a common cause of catheter-related bloodstream infections (CR-BSI), in part due to its strong propensity to form biofilms. Drug repurposing is an approach that might identify agents that are able to overcome antifungal drug resistance within biofilms. Quinacrine (QNC) is clinically active against the eukaryotic protozoan parasites Plasmodium and Giardia. We sought to investigate the antifungal activity of QNC against C. albicans biofilms. C. albicans biofilms were incubated with QNC at serially increasing concentrations (4 to 2,048 mug/ml) and assessed using a 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay in a static microplate model. Combinations of QNC and standard antifungals were assayed using biofilm checkerboard analyses. To define a mechanism of action, QNC was assessed for the inhibition of filamentation, effects on endocytosis, and pH-dependent activity. High-dose QNC was effective for the prevention and treatment of C. albicans biofilms in vitro. QNC with fluconazole had no interaction, while the combination of QNC and either caspofungin or amphotericin B demonstrated synergy. QNC was most active against planktonic growth at alkaline pH. QNC dramatically inhibited filamentation. QNC accumulated within vacuoles as expected and caused defects in endocytosis. A tetracycline-regulated VMA3 mutant lacking vacuolar ATPase (V-ATPase) function demonstrated increased susceptibility to QNC. These experiments indicate that QNC is active against C. albicans growth in a pH-dependent manner. Although QNC activity is not biofilm specific, QNC is effective in the prevention and treatment of biofilms. QNC antibiofilm activity likely occurs via several independent mechanisms: vacuolar alkalinization, inhibition of endocytosis, and impaired filamentation. Further investigation of QNC for the treatment and prevention of biofilm-related Candida CR-BSI is warranted.
Descriptors
Links
Book Title
Database
Publisher
American Society for Microbiology. All Rights Reserved
Data Source
Authors
Kulkarny,V.V., Chavez-Dozal,A., Rane,H.S., Jahng,M., Bernardo,S.M., Parra,K.J., Lee,S.A.
Original/Translated Title
URL
Date of Electronic
20141006
PMCID
PMC4249548
Editors
Quit attempt correlates among smokers by race/ethnicity 2011 Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 4770 Buford Highway, Atlanta, GA 30341, USA. jkahende@cdc.gov
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of environmental research and public health
Periodical, Abbrev.
Int.J.Environ.Res.Public.Health.
Pub Date Free Form
Oct
Volume
8
Issue
10
Start Page
3871
Other Pages
3888
Notes
LR: 20151119; JID: 101238455; OID: NLM: PMC3210587; OTO: NOTNLM; 2011/08/31 [received]; 2011/09/23 [accepted]; 2011/09/28 [epublish]; ppublish
Place of Publication
Switzerland
ISSN/ISBN
1660-4601; 1660-4601
Accession Number
PMID: 22073018
Language
eng
SubFile
Journal Article; IM
DOI
10.3390/ijerph8103871 [doi]
Output Language
Unknown(0)
PMID
22073018
Abstract
INTRODUCTION: Cigarette smoking is the leading preventable cause of premature deaths in the U.S., accounting for approximately 443,000 deaths annually. Although smoking prevalence in recent decades has declined substantially among all racial/ethnic groups, disparities in smoking-related behaviors among racial/ethnic groups continue to exist. Two of the goals of Healthy People 2020 are to reduce smoking prevalence among adults to 12% or less and to increase smoking cessation attempts by adult smokers from 41% to 80%. Our study assesses whether correlates of quit attempts vary by race/ethnicity among adult (>/= 18 years) smokers in the U.S. Understanding racial/ethnic differences in how both internal and external factors affect quit attempts is important for targeting smoking-cessation interventions to decrease tobacco-use disparities. METHODS: We used 2003 Tobacco Use Supplement to the Current Population Survey (CPS) data from 16,213 adults to examine whether the relationship between demographic characteristics, smoking behaviors, smoking policies and having made a quit attempt in the past year varied by race/ethnicity. RESULTS: Hispanics and persons of multiple races were more likely to have made a quit attempt than whites. Overall, younger individuals and those with >high school education, who smoked fewer cigarettes per day and had smoked for fewer years were more likely to have made a quit attempt. Having a smoke-free home, receiving a doctor's advice to quit, smoking menthol cigarettes and having a greater time to when you smoked your first cigarette of the day were also associated with having made a quit attempt. The relationship between these four variables and quit attempts varied by race/ethnicity; most notably receiving a doctor's advice was not related to quit attempts among Asian American/Pacific Islanders and menthol use among whites was associated with a lower prevalence of quit attempts while black menthol users were more likely to have made a quit attempt than white non-menthol users. CONCLUSIONS: Most correlates of quit attempts were similar across all racial/ethnic groups. Therefore population-based comprehensive tobacco control programs that increase quit attempts and successful cessation among all racial/ethnic groups should be continued and expanded. Additional strategies may be needed to encourage quit attempts among less educated, older, and more addicted smokers.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Kahende,J.W., Malarcher,A.M., Teplinskaya,A., Asman,K.J.
Original/Translated Title
URL
Date of Electronic
20110928
PMCID
PMC3210587
Editors
Quit attempts and intention to quit cigarette smoking among young adults in the United States 2007 Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7337, USA. faganp@mail.nih.gov
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Public Health
Periodical, Abbrev.
Am.J.Public Health
Pub Date Free Form
Aug
Volume
97
Issue
8
Start Page
1412
Other Pages
1420
Notes
LR: 20140904; GR: N01-CO-12400/CO/NCI NIH HHS/United States; JID: 1254074; OID: NLM: PMC1931471; 2007/06/28 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1541-0048; 0090-0036
Accession Number
PMID: 17600244
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; AIM; IM
DOI
AJPH.2006.103697 [pii]
Output Language
Unknown(0)
PMID
17600244
Abstract
OBJECTIVES: We investigated variables associated with quitting behaviors among current, daily, and nondaily young adult smokers in the United States. METHODS: Data from the national 2003 Tobacco Use Special Cessation Supplement to the Current Population Survey were analyzed to identify factors associated with quit attempts and serious intention to quit among young adult smokers aged 18 to 30 years (n=7912). RESULTS: Daily smokers who smoked 20 or more cigarettes per day, had their first cigarette within 30 minutes of waking, and smoked no usual type were less likely than were their comparison groups to have 1 more or quit attempts. Nondaily smokers who were male, Hispanic, and smoked no usual type of cigarette were also less likely than were their comparison groups to report 1 or more quit attempts. Although unemployed nondaily smokers were more likely than were the employed to report intention to quit, nondaily smokers with an annual family income of $25,000 to $49,000 were less likely than were higher-income families to report intention to quit. CONCLUSIONS: Nicotine dependence measures were significantly associated with quitting and intention to quit among daily smokers, but sociodemographics were associated with quitting and intention to quit among nondaily smokers.
Descriptors
Adolescent, Adult, Cross-Sectional Studies, Female, Health Behavior, Humans, Intention, Logistic Models, Male, Multivariate Analysis, Prevalence, Smoking/epidemiology/prevention & control/psychology, Smoking Cessation/ethnology/psychology/statistics & numerical data, Socioeconomic Factors, United States/epidemiology
Links
Book Title
Database
Publisher
Data Source
Authors
Fagan,P., Augustson,E., Backinger,C. L., O'Connell,M. E., Vollinger,R. E.,Jr, Kaufman,A., Gibson,J. T.
Original/Translated Title
URL
Date of Electronic
20070628
PMCID
PMC1931471
Editors
Quit attempts and quit rates among menthol and nonmenthol smokers in the United States 2011 Department of Economics, University of Baltimore, Baltimore, MD, USA. dlevy@ubalt.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Public Health
Periodical, Abbrev.
Am.J.Public Health
Pub Date Free Form
Jul
Volume
101
Issue
7
Start Page
1241
Other Pages
1247
Notes
LR: 20150204; JID: 1254074; 1490-04-6 (Menthol); OID: NLM: PMC3110228; 2011/05/12 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1541-0048; 0090-0036
Accession Number
PMID: 21566032
Language
eng
SubFile
Journal Article; AIM; IM
DOI
10.2105/AJPH.2011.300178 [doi]
Output Language
Unknown(0)
PMID
21566032
Abstract
OBJECTIVES: We compared quit attempts and quit rates among menthol and nonmenthol cigarette smokers in the United States. METHODS: We used data from the 2003 and 2006-2007 waves of the large, nationally representative Tobacco Use Supplement to the Current Population Survey with control for state-level tobacco control spending, prices, and smoke-free air laws. We estimated mean prevalence, quit rates, and multivariate logistic regression equations by using self-respondent weights for menthol and nonmenthol smokers. RESULTS: In 2003 and 2007, 70% of smokers smoked nonmenthol cigarettes, 26% smoked menthol cigarettes, and 4% had no preference. Quit attempts were 4.3% higher in 2003 and 8.8% higher in 2007 among menthol than nonmenthol smokers. The likelihood of quitting was 3.5% lower for quitting in the past year and 6% lower for quitting in the past 5 years in menthol compared with nonmenthol smokers. Quit success in the past 5 years was further eroded among menthol-smoking Blacks and young adults. CONCLUSIONS: Menthol smokers are more likely to make quit attempts, but are less successful at staying quit. The creation of menthol preference through marketing may reduce quit success.
Descriptors
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Database
Publisher
Data Source
Authors
Levy,D.T., Blackman,K., Tauras,J., Chaloupka,F.J., Villanti,A.C., Niaura,R.S., Vallone,D.M., Abrams,D.B.
Original/Translated Title
URL
Date of Electronic
20110512
PMCID
PMC3110228
Editors
Quit history, intentions to quit, and reasons for considering quitting among tobacco users in India: findings from the Tobacco Control Policy Evaluation India Wave 1 Survey 2014 Healis Sekhsaria Institute for Public Health, Navi Mumbai, Maharashtra, India.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Indian journal of cancer
Periodical, Abbrev.
Indian J.Cancer
Pub Date Free Form
Dec
Volume
51 Suppl 1
Issue
Start Page
S39
Other Pages
45
Notes
LR: 20151028; GR: 115216/Canadian Institutes of Health Research/Canada; GR: 79551/Canadian Institutes of Health Research/Canada; GR: P01 CA138389/CA/NCI NIH HHS/United States; GR: P01-CA138389/CA/NCI NIH HHS/United States; JID: 0112040; NIHMS708516; OID:
Place of Publication
India
ISSN/ISBN
1998-4774; 0019-509X
Accession Number
PMID: 25526247
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.4103/0019-509X.147467 [doi]
Output Language
Unknown(0)
PMID
25526247
Abstract
BACKGROUND: Global Adult Tobacco Survey India 2009-2010 revealed that more than one-third (35%) of adults in India use tobacco in some form: 21% use smokeless tobacco, 9% smoke, and 5% are mixed users (they smoke and use smokeless tobacco), and the quit rate is very low. In an effort to decrease prevalence of tobacco use, it is thus important to understand the factors that are related to intention to quit among Indian tobacco users. Research has shown consistently that intention to quit is a strong predictor of future quitting. The present study reports the factors encouraging quitting tobacco products in India. SUBJECTS AND METHODS: Cross-sectional data from Wave 1 of the International Tobacco Control Policy Evaluation India Survey conducted in four cities and surrounding rural areas (i.e. Mumbai [Maharashtra], Patna [Bihar], Indore [Madhya Pradesh], and Kolkata [West Bengal]) between August 2010 and December 2011 were analyzed. A total of 8051 tobacco users (15+ years) were randomly sampled from 8586 households: 1255 smokers, 5991 smokeless users, and 805 mixed (smoke and smokeless) users. Validated, standardized questions were asked about current tobacco use, intention to quit, and factors encouraging quitting. RESULTS: Overall, 19.6% of tobacco users intended to quit. Smokers had less intention to quit as compared to smokeless tobacco users whereas mixed users had more intention to quit (odds ratio [OR] =1.48, 95% confidence interval [CI] =1.12-1.97) compared to smokeless tobacco users. Highly educated people were more likely to report intention to quit (OR = 1.82, 95% CI = 1.09-3.02) compared to less educated. Advice by doctors to quit tobacco had a strong impact on intention to quit (OR = 1.68, CI = 1.29-2.15). Tobacco users who were exposed to antitobacco messages at work places (OR = 1.74, CI = 1.23-2.46), at restaurants (OR = 1.65, CI = 1.12-2.43), bars (OR = 1.81, CI = 1.07-3.06), on public transportation (OR = 2.14, CI = 1.49-3.08) and on tobacco packages (OR = 1.77, CI = 1.29-2.14) also expressed greater intention to quit tobacco use. CONCLUSION: Around one-fifth of tobacco users in India intended to quit tobacco use. Higher education, doctor's advice, and antitobacco messages were positively associated with users' intention to quit tobacco.
Descriptors
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Database
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Data Source
Authors
Dhumal,G.G., Pednekar,M.S., Gupta,P.C., Sansone,G.C., Quah,A.C., Bansal-Travers,M., Fong,G.T.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4527990
Editors
Quit now? Quit soon? Quit when you're ready? Insights about target quit dates for smoking cessation from an online quit date tool 2014 Schroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, DC, United States.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of medical Internet research
Periodical, Abbrev.
J.Med.Internet Res.
Pub Date Free Form
17-Feb
Volume
16
Issue
2
Start Page
e55
Other Pages
Notes
LR: 20150515; ClinicalTrials.gov/NCT00282009; GR: R01 CA104836/CA/NCI NIH HHS/United States; GR: R01 CA104836/CA/NCI NIH HHS/United States; JID: 100959882; OID: NLM: PMC3958692; OTO: NOTNLM; 2013/11/06 [received]; 2014/01/28 [accepted]; 2013/12/09 [revise
Place of Publication
Canada
ISSN/ISBN
1438-8871; 1438-8871
Accession Number
PMID: 24534139
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM
DOI
10.2196/jmir.3086 [doi]
Output Language
Unknown(0)
PMID
24534139
Abstract
BACKGROUND: Setting a target quit date (TQD) is often an important component in smoking cessation treatment, but ambiguity remains concerning the optimal timing (ie, quitting spontaneously versus delaying to prepare). OBJECTIVE: We examined four questions about the timing of TQDs and smoking outcomes in secondary analyses of The iQUITT Study, a randomized trial of Internet and telephone treatment for cessation: (1) What are the characteristics of TQDs set using an online interactive quit date tool?, (2) What are the characteristics of individuals who use a quit date tool and do they differ from those who do not?, (3) Are there differences in smoker characteristics, treatment utilization, and cessation outcomes based TQD timing?, and (4) Is maintenance of an initial TQD predictive of abstinence or do changes to TQDs lead to cessation? METHODS: A total of 825 adult current cigarette smokers were randomized to enhanced Internet or enhanced Internet plus telephone counseling. Latency to TQD in days was calculated as the date difference between the initial TQD and enhanced Internet registration; prospective TQD setters were stratified into four latency groups (0, 1-14, 15-28, 29+ days). Baseline variables, website utilization, and 3-month cessation outcomes were examined between prospective TQD groups. Desire and confidence to quit, number of TQDs, and website logins were tested as predictors of 30-day point prevalence abstinence (ppa) at 3 months (responder-only analyses). Classification and regression tree (CART) analysis explored interactions among baseline variables, website utilization, and latency to TQD as predictors of 30-day ppa. RESULTS: There were few baseline differences between individuals who used the quit date tool and those who did not. Prospective TQDs were set as follows: registration day was 17.1% (73/427), 1-14 days was 37.7% (161/427), 15-28 days was 18.5% (79/427), and 29+ days was 26.7% (114/427). Participants with a TQD within 2 weeks had higher baseline self-efficacy scores but did not differ on smoking variables. Individuals whose TQD was the same day as registration had the highest logins, page views, number of TQDs set using the tool, and messages sent to other members. Logistic regression revealed a significant interaction between number of TQDs and website logins for 30-day ppa (P=.005). Among those with high logins, 41.8% (33/79) with 1 TQD were abstinent versus 25.9% (35/135) with 2+TQDs. Logins and self-efficacy predicted 30-day ppa in the CART model. CONCLUSIONS: TQD timing did not predict cessation outcomes in standard or exploratory analyses. Self-efficacy and an apparent commitment to an initial TQD were the components most highly related to abstinence but only via interactions with website utilization. Findings highlight the importance of feeling efficacious about handling specific smoking situations and engaging with treatment. Additional research focused on increasing engagement in Web-based cessation studies is needed. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00282009; http://clinicaltrials.gov/show/NCT00282009 (Archived by WebCite at http://www.webcitation.org/6Kt7NrXDl).
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Cobb,C.O., Niaura,R.S., Donaldson,E.A., Graham,A.L.
Original/Translated Title
URL
Date of Electronic
20140217
PMCID
PMC3958692
Editors
Quit smoking advice from health professionals in Taiwan: the role of funding policy and smoker socioeconomic status 2010 National Taiwan Normal University, Taipei 10610, Taiwan. fongchingchang@ntnu.edu.tw
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Feb
Volume
19
Issue
1
Start Page
44
Other Pages
49
Notes
LR: 20151119; JID: 9209612; OID: NLM: PMC2921261; 2009/12/03 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 19965797
Language
eng
SubFile
Journal Article; IM
DOI
10.1136/tc.2009.031435 [doi]
Output Language
Unknown(0)
PMID
19965797
Abstract
OBJECTIVES: In 2002, Taiwan launched a program to encourage doctors to provide brief cessation counselling to their patients during routine outpatient visits. This study is to compare and analyse the annual prevalence rate of receiving advice to quit smoking from health professionals before (2004) and after (2005, 2006) the increase in funding and the withdrawal of additional funding (2007). METHODS: We analysed pooled data from 2004 to 2007 Taiwan Adult Tobacco Survey, an annual random digit dialling telephone survey, to estimate the prevalence of receiving quit advice among ever smokers across these years. Smoking characteristics and the socioeconomic factors of smokers associated with receipt of advice to quit smoking were also examined. RESULTS: The prevalence rate of receiving quit advice increased from 21.1% in 2004 to 28.2% in 2006, and then decreased slightly to 27.6% in 2007 after the funds were cut. Multivariate analyses results indicated that increasing financing for smoking cessation services in 2005, being male, older, a daily cigarette user, having previously attempted to quit, perceiving oneself as having poor health and being aware of the benefits of smoking cessation services were significantly positively associated with receiving quit advice from health professionals. In contrast, smokers who were younger, female and occasional cigarette users were less likely to receive quit advice. Also, smokers with socioeconomic disadvantages were not less likely to receive quit advice. CONCLUSIONS: During the period of increased funding for smoking cessation services, the rates of receiving quit advice increased among all smokers and across different socioeconomic groups.
Descriptors
Adolescent, Adult, Age Factors, Aged, Cross-Sectional Studies, Data Collection, Directive Counseling/economics/methods, Female, Humans, Male, Middle Aged, Multivariate Analysis, Patient Education as Topic/economics/methods, Practice Patterns, Physicians'/economics/statistics & numerical data, Prevalence, Sex Factors, Smoking Cessation/economics/methods, Socioeconomic Factors, Taiwan, Young Adult
Links
Book Title
Database
Publisher
Data Source
Authors
Chang,F. C., Hu,T. W., Lo,S. Y., Yu,P. T., Chao,K. Y., Hsiao,M. L.
Original/Translated Title
URL
Date of Electronic
20091203
PMCID
PMC2921261
Editors
Quit tobacco clinics in Bahrain: smoking cessation rates and patient satisfaction 2017
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco induced diseases
Periodical, Abbrev.
Pub Date Free Form
Volume
15
Issue
1
Start Page
7
Other Pages
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
BioMed Central
Data Source
google
Authors
Hamadeh, Randah Ribhi, Ahmed, Jamil, Al-Kawari, Maha, Bucheeri, Sharifa
Original/Translated Title
URL
Date of Electronic
PMCID
Editors