WTS database

Title	Pub Year	Author Sort descending	SearchLink
Role of snus in initiation and cessation of tobacco smoking in Sweden	2006	Institute for Tobacco Studies, Stockholm, Sweden. tobstud@algonet.se	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Jun Volume 15 Issue 3 Start Page 210 Other Pages 214 Notes LR: 20140909; JID: 9209612; OID: NLM: PMC2564662; ppublish Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 16728752 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 15/3/210 [pii] Output Language Unknown(0) PMID 16728752 Abstract OBJECTIVE: To examine patterns of smoking and snus use and identify individual pathways of Swedish tobacco users in order to clarify whether snus use is associated with increased or decreased smoking. METHODS: Retrospective analysis of data from a cross-sectional survey completed by 6752 adult Swedes in 2001-2 focusing on identifying tobacco use history by survey items on current and prior tobacco use and smoking initiation and cessation procedures. RESULTS: 15% of the men and 19% of the women completing the survey were daily smokers. 21% of the men and 2% of the women were daily snus users. Almost all (91%) male daily smoking began before the age of 23 years, whereas initiation of daily snus use continued throughout the age range (33% of initiation after age 22). 20% of male primary snus users started daily smoking compared to 47% of non-primary snus users. Thus, the odds of initiating daily smoking were significantly lower for men who had started using snus than for those who had not (odds ratio (OR) 0.28, 95% confidence interval (CI) 0.22 to 0.36). Among male primary smokers, 28% started secondary daily snus use and 73% did not. 88% of those secondary snus users had ceased daily smoking completely by the time of the survey as compared with 56% of those primary daily smokers who never became daily snus users (OR 5.7, 95% CI 4.9 to 8.1). Among men who made attempts to quit smoking, snus was the most commonly used cessation aid, being used by 24% on their latest quit attempt. Of those men who had used one single cessation aid 58% had used snus, as compared with 38% for all nicotine replacement therapy products together. Among men who used snus as a single aid, 66% succeeded in quitting completely, as compared with 47% of those using nicotine gum (OR 2.2, 95% CI 1.3 to 3.7) or 32% for those using the nicotine patch (OR 4.2, 95% CI 2.1 to 8.6). Women using snus as an aid were also significantly more likely to quit smoking successfully than those using nicotine patches or gum. CONCLUSION: Use of snus in Sweden is associated with a reduced risk of becoming a daily smoker and an increased likelihood of stopping smoking. Descriptors Adolescent, Adult, Age Distribution, Aged, Female, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Sex Distribution, Smoking/epidemiology/prevention & control, Smoking Cessation/methods/statistics & numerical data, Sweden/epidemiology, Tobacco Use Disorder/epidemiology/rehabilitation, Tobacco, Smokeless Links Book Title Database Publisher Data Source Authors Ramstrom,L. M., Foulds,J. Original/Translated Title URL Date of Electronic PMCID PMC2564662 Editors
Contribution of fine particulate matter sources to indoor exposure in bars, restaurants, and cafes	2010	Institute for Work and Health [Institut universitaire romand de Sante au Travail], University of Lausanne and University of Geneva, Lausanne, Switzerland.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Indoor air Periodical, Abbrev. Indoor Air Pub Date Free Form Jun Volume 20 Issue 3 Start Page 204 Other Pages 212 Notes LR: 20130520; JID: 9423515; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); 2010/02/01 [aheadofprint]; ppublish Place of Publication Denmark ISSN/ISBN 1600-0668; 0905-6947 Accession Number PMID: 20408901 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1111/j.1600-0668.2010.00645.x [doi] Output Language Unknown(0) PMID 20408901 Abstract This study investigated the contribution of sources and establishment characteristics, on the exposure to fine particulate matter (PM(2.5)) in the non-smoking sections of bars, cafes, and restaurants in central Zurich. PM(2.5)-exposure was determined with a nephelometer. A random sample of hospitality establishments was investigated on all weekdays, from morning until midnight. Each visit lasted 30 min. Numbers of smokers and other sources, such as candles and cooking processes, were recorded, as were seats, open windows, and open doors. Ambient air pollution data were obtained from public authorities. Data were analysed using robust MM regression. Over 14 warm, sunny days, 102 establishments were measured. Average establishment PM(2.5) concentrations were 64.7 microg/m(3) (s.d. = 73.2 microg/m(3), 30-min maximum 452.2 microg/m(3)). PM(2.5) was significantly associated with the number of smokers, percentage of seats occupied by smokers, and outdoor PM. Each smoker increased PM(2.5) on average by 15 microg/m(3). No associations were found with other sources, open doors or open windows. Bars had more smoking guests and showed significantly higher concentrations than restaurants and cafes. Smokers were the most important PM(2.5)-source in hospitality establishments, while outdoor PM defined the baseline. Concentrations are expected to be even higher during colder, unpleasant times of the year. PRACTICAL IMPLICATIONS: Smokers and ambient air pollution are the most important sources of fine airborne particulate matter (PM(2.5)) in the non-smoking sections of bars, restaurants, and cafes. Other sources do not significantly contribute to PM(2.5)-levels, while opening doors and windows is not an efficient means of removing pollutants. First, this demonstrates the impact that even a few smokers can have in affecting particle levels. Second, it implies that creating non-smoking sections, and using natural ventilation, is not sufficient to bring PM(2.5) to levels that imply no harm for employees and non-smoking clients. Descriptors Air Pollutants/analysis, Air Pollution, Indoor/analysis, Environmental Monitoring, Humans, Humidity, Nephelometry and Turbidimetry, Particulate Matter/analysis, Public Facilities/classification/standards, Restaurants/classification/instrumentation/standards, Seasons, Temperature, Time Factors, Tobacco Smoke Pollution/analysis, Ventilation Links Book Title Database Publisher Data Source Authors Daly,B. J., Schmid,K., Riediker,M. Original/Translated Title URL Date of Electronic 20100201 PMCID Editors
Identification and expression of blaCTX-M-14 and blaCTX-M-24	2004	Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, China.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Zhonghua yi xue za zhi Periodical, Abbrev. Zhonghua Yi Xue Za Zhi Pub Date Free Form 2-Sep Volume 84 Issue 17 Start Page 1454 Other Pages 1459 Notes LR: 20131121; JID: 7511141; 0 (Anti-Bacterial Agents); 0 (DNA, Bacterial); EC 3.5.2.- (beta-lactamase CTX-M-14); EC 3.5.2.6 (beta-Lactamases); N2GI8B1GK7 (Cefotaxime); ppublish Place of Publication China ISSN/ISBN 0376-2491; 0376-2491 Accession Number PMID: 15500745 Language chi SubFile English Abstract; Journal Article; Research Support, Non-U.S. Gov't; IM DOI Output Language Unknown(0) PMID 15500745 Abstract OBJECTIVE: To identify the ESBL gene and the prevalence in Escherichia coli and Klebsiella pneumoniae strain isolated from Huashan Hospital, Shanghai. METHODS: Isolates were confirmed as an ESBL producing strain by double-disk synergy test and NCCLS Confirmatory Test. Antibiotic susceptibilities were determined by standard agar dilution procedure on Mueller-Hinton agar. To determine whether the resistance was transferable, the conjugation experiment was performed; plasmids were isolated from clinical isolates and transcojugants. The partial bla(gene) of ESBL producing isolates and their transcojugants were detected by PCR using universal primers for TEM, SHV, CTX-M-1group, Toho-1group, CTX-M-13group respectively. The entire bla(CTX-M-13) group were amplified by PCR using the primers outside the Open Reading Frame (ORF) of CTX-M-13group beta-lactamases; the PCR products of entire bla(CTX-M-13)group were cloned into vector and the recombinant plasmids were transformed into the recipient strain for expression; the PCR products were also directly sequenced and analyzed; the clinical isolates of ESBL producers were detected by PFGE. RESULTS: ESBL producers were resistant to most beta-lactams and non-beta-lactams. Most transconjugants were obtained at frequency of 10(-4) approximately 10(-5) and resistance to non-beta-lactams was cotransferred with the ESBL activity to the transconjugant. A plasmid of about > 23.1 kb was obtained from each tansconjugant by plasmid extraction. Partial gene amplification products of CTX-M-13 group gene were obtained from isolates and their transconjugants. The bla(CTX-M-13)group from 4 transconjugants were identified as bla(CTX-M-14), and other six were bla(CTX-M-24); those ESBLs were mediated by plasmids (> 23.1 kb); the transformants producing CTX-M-14 or CTX-M-24 were resistant to most beta-lactams, which were much more resistant to cefotaxime than to ceftazidine; PFGE patterns of those isolates were different. CONCLUSION: clinical isolate of Escherichia coli and Klebsiella pneumoniae isolated from Huashan Hospital, Shanhai produced CTX-M-14 or CTX-M-24, which caused the isolate resistant to most beta-lactams; no clone spread in those isolates was found. Descriptors Anti-Bacterial Agents/pharmacology, Cefotaxime/pharmacology, DNA, Bacterial/genetics, Drug Resistance, Bacterial/genetics, Escherichia coli/enzymology/genetics, Escherichia coli Infections/microbiology, Genes, Bacterial/genetics, Humans, Klebsiella Infections/microbiology, Klebsiella pneumoniae/enzymology/genetics, beta-Lactam Resistance/genetics, beta-Lactamases/genetics/metabolism Links Book Title Database Publisher Data Source Authors Xiong,Z. Z., Zhu,D. M., Wang,F., Zhang,Y. Y. Original/Translated Title URL Date of Electronic PMCID Editors
Biodiversity in Oscypek, a traditional Polish cheese, determined by culture-dependent and -independent approaches	2012	Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Applied and Environmental Microbiology Periodical, Abbrev. Appl.Environ.Microbiol. Pub Date Free Form Mar Volume 78 Issue 6 Start Page 1890 Other Pages 1898 Notes LR: 20150128; JID: 7605801; 0 (DNA, Bacterial); 0 (DNA, Fungal); 0 (DNA, Ribosomal); 0 (RNA, Bacterial); 0 (RNA, Fungal); 0 (RNA, Ribosomal); 0 (RNA, Ribosomal, 16S); 0 (RNA, ribosomal, 26S); OID: NLM: PMC3298175; 2012/01/13 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1098-5336; 0099-2240 Accession Number PMID: 22247135 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AEM.06081-11 [doi] Output Language Unknown(0) PMID 22247135 Abstract Oscypek is a traditional Polish scalded-smoked cheese, with a protected-designation-of-origin (PDO) status, manufactured from raw sheep's milk without starter cultures in the Tatra Mountains region of Poland. This study was undertaken in order to gain insight into the microbiota that develops and evolves during the manufacture and ripening stages of Oscypek. To this end, we made use of both culturing and the culture-independent methods of PCR followed by denaturing gradient gel electrophoresis (PCR-DGGE) and pyrosequencing of 16S rRNA gene amplicons. The culture-dependent technique and PCR-DGGE fingerprinting detected the predominant microorganisms in traditional Oscypek, whereas the next-generation sequencing technique (454 pyrosequencing) revealed greater bacterial diversity. Besides members of the most abundant bacterial genera in dairy products, e.g., Lactococcus, Lactobacillus, Leuconostoc, Streptococcus, and Enterococcus, identified by all three methods, other, subdominant bacteria belonging to the families Bifidobacteriaceae and Moraxellaceae (mostly Enhydrobacter), as well as various minor bacteria, were identified by pyrosequencing. The presence of bifidobacterial sequences in a cheese system is reported for the first time. In addition to bacteria, a great diversity of yeast species was demonstrated in Oscypek by the PCR-DGGE method. Culturing methods enabled the determination of a number of viable microorganisms from different microbial groups and their isolation for potential future applications in specific cheese starter cultures. Descriptors Links Book Title Database Publisher Data Source Authors Alegria,A., Szczesny,P., Mayo,B., Bardowski,J., Kowalczyk,M. Original/Translated Title URL Date of Electronic 20120113 PMCID PMC3298175 Editors
Diversity of lactic acid bacteria in suan-tsai and fu-tsai, traditional fermented mustard products of Taiwan	2009	Institute of Biochemistry and Molecular Biology, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Pei-Tou, Taipei 11221, Taiwan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of food microbiology Periodical, Abbrev. Int.J.Food Microbiol. Pub Date Free Form 15-Nov Volume 135 Issue 3 Start Page 203 Other Pages 210 Notes JID: 8412849; 0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S); 2009/02/19 [received]; 2009/06/28 [revised]; 2009/07/23 [accepted]; 2009/08/04 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1879-3460; 0168-1605 Accession Number PMID: 19700215 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.ijfoodmicro.2009.07.032 [doi] Output Language Unknown(0) PMID 19700215 Abstract Fu-tsai and suan-tsai are spontaneously fermented mustard products traditionally prepared by the Hakka tribe of Taiwan. We chose 5 different processing stages of these products for analysis of the microbial community of lactic acid bacteria (LAB) by 16S rRNA gene sequencing. From 500 LAB isolates we identified 119 representative strains belonging to 5 genera and 18 species, including Enterococcus (1 species), Lactobacillus (11 species), Leuconostoc (3 species), Pediococcus (1 species), and Weissella (2 species). The LAB composition of mustard fermented for 3 days, known as the Mu sample, was the most diverse, with 11 different LAB species being isolated. We used sequence analysis of the 16S rRNA gene to identify the LAB strains and analysis of the dnaA, pheS, and rpoA genes to identify 13 LAB strains for which identification by 16S rRNA gene sequences was not possible. These 13 strains were found to belong to 5 validated known species: Lactobacillus farciminis, Leuconostoc mesenteroides, Leuconostoc pseudomesenteroides, Weissella cibaria, and Weissella paramesenteroides, and 5 possibly novel Lactobacillus species. These results revealed that there is a high level of diversity in LAB at the different stages of fermentation in the production of suan-tsai and fu-tsai. Descriptors Bacterial Typing Techniques, Base Sequence, Biodiversity, DNA, Ribosomal/analysis, Fermentation, Food Handling, Food Microbiology, Genes, Bacterial, Humans, Lactobacillaceae/classification/genetics/isolation & purification, Mustard Plant, Phylogeny, RNA, Ribosomal, 16S, Salt-Tolerance, Sequence Analysis, DNA, Taiwan Links Book Title Database Publisher Data Source Authors Chao,S. H., Wu,R. J., Watanabe,K., Tsai,Y. C. Original/Translated Title URL Date of Electronic 20090804 PMCID Editors
Microbial diversity analysis of fermented mung beans (Lu-Doh-Huang) by using pyrosequencing and culture methods	2013	Institute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei, Taiwan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PloS one Periodical, Abbrev. PLoS One Pub Date Free Form 20-May Volume 8 Issue 5 Start Page e63816 Other Pages Notes LR: 20150426; JID: 101285081; 0 (Bacterial Proteins); 0 (RNA, Ribosomal, 16S); EC 2.7.7.- (Rec A Recombinases); OID: NLM: PMC3659079; 2013 [ppublish]; 2013/01/25 [received]; 2013/04/02 [accepted]; 2013/05/20 [epublish]; epublish Place of Publication United States ISSN/ISBN 1932-6203; 1932-6203 Accession Number PMID: 23700436 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1371/journal.pone.0063816 [doi] Output Language Unknown(0) PMID 23700436 Abstract In Taiwanese alternative medicine Lu-doh-huang (also called Pracparatum mungo), mung beans are mixed with various herbal medicines and undergo a 4-stage process of anaerobic fermentation. Here we used high-throughput sequencing of the 16S rRNA gene to profile the bacterial community structure of Lu-doh-huang samples. Pyrosequencing of samples obtained at 7 points during fermentation revealed 9 phyla, 264 genera, and 586 species of bacteria. While mung beans were inside bamboo sections (stages 1 and 2 of the fermentation process), family Lactobacillaceae and genus Lactobacillus emerged in highest abundance; Lactobacillus plantarum was broadly distributed among these samples. During stage 3, the bacterial distribution shifted to family Porphyromonadaceae, and Butyricimonas virosa became the predominant microbial component. Thereafter, bacterial counts decreased dramatically, and organisms were too few to be detected during stage 4. In addition, the microbial compositions of the liquids used for soaking bamboo sections were dramatically different: Exiguobacterium mexicanum predominated in the fermented soybean solution whereas B. virosa was predominant in running spring water. Furthermore, our results from pyrosequencing paralleled those we obtained by using the traditional culture method, which targets lactic acid bacteria. In conclusion, the microbial communities during Lu-doh-huang fermentation were markedly diverse, and pyrosequencing revealed a complete picture of the microbial consortium. Descriptors Links Book Title Database Publisher Data Source Authors Chao,S.H., Huang,H.Y., Chang,C.H., Yang,C.H., Cheng,W.S., Kang,Y.H., Watanabe,K., Tsai,Y.C. Original/Translated Title URL Date of Electronic 20130520 PMCID PMC3659079 Editors
Diversity of lactic acid bacteria in fermented brines used to make stinky tofu	2008	Institute of Biochemistry, National Yang-Ming University, 155, Sec. 2, Li-Nong Street, Pei-Tou, Taipei 11221, Taiwan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of food microbiology Periodical, Abbrev. Int.J.Food Microbiol. Pub Date Free Form 31-Mar Volume 123 Issue 2-Jan Start Page 134 Other Pages 141 Notes LR: 20081121; JID: 8412849; 0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S); 2007/04/17 [received]; 2007/11/30 [revised]; 2007/12/18 [accepted]; 2008/01/30 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 0168-1605; 0168-1605 Accession Number PMID: 18234387 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.ijfoodmicro.2007.12.010 [doi] Output Language Unknown(0) PMID 18234387 Abstract Stinky tofu is a kind of fermented tofu with a strong odor. Although stinky tofu is a very popular snack in the Asian region, the community of microbes, and especially lactic acid bacteria (LAB), indigenous to the fermented brine from which it is made remains poorly described. We examined 168 isolates obtained from the original fermented brine (brine A) and two brines in which the hard tofu (brine B) and soft tofu (brine C) had been soaked. Through random amplified polymorphic DNA (RAPD) analysis for typing and 16S rDNA sequencing, 136 representative strains were identified as belonging to 7 genera and 32 species: Enterococcus (2 species), Lactobacillus (14 species), Lactococcus (3 species), Leuconostoc (6 species), Pediococcus (1 species), Streptococcus (2 species), and Weissella (4 species). The LAB composition of brine A was the most diverse: 19 different species were isolated, and 9 of them were classified as Lactobacillus species. The 16S rDNA sequences of 9 strains (6 from brine A and 3 from brine C) showed low values of similarity (below 98%) with currently known species by analysis using the FASTA software. Thus, a wide variety of LAB strains were associated with the fermentation of stinky tofu brines. Descriptors DNA, Ribosomal/chemistry/genetics, Fermentation, Gene Amplification, Genetic Variation, Hydrogen-Ion Concentration, Lactobacillus/classification/genetics/isolation & purification, Phylogeny, RNA, Ribosomal, 16S/analysis, Random Amplified Polymorphic DNA Technique/methods, Sequence Analysis, DNA, Soy Foods/microbiology, Species Specificity Links Book Title Database Publisher Data Source Authors Chao,S. H., Tomii,Y., Watanabe,K., Tsai,Y. C. Original/Translated Title URL Date of Electronic 20080130 PMCID Editors
Implicit motivational impact of pictorial health warning on cigarette packs	2013	Institute of Biophysics Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PloS one Periodical, Abbrev. PLoS One Pub Date Free Form 15-Aug Volume 8 Issue 8 Start Page e72117 Other Pages Notes LR: 20150423; JID: 101285081; OID: NLM: PMC3744501; 2013 [ecollection]; 2013/02/25 [received]; 2013/07/06 [accepted]; 2013/08/15 [epublish]; epublish Place of Publication United States ISSN/ISBN 1932-6203; 1932-6203 Accession Number PMID: 23977223 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1371/journal.pone.0072117 [doi] Output Language Unknown(0) PMID 23977223 Abstract OBJECTIVE: The use of pictorial warning labels on cigarette packages is one of the provisions included in the first ever global health treaty by the World Health Organization against the tobacco epidemic. There is substantial evidence demonstrating the effectiveness of graphic health warning labels on intention to quit, thoughts about health risks and engaging in cessation behaviors. However, studies that address the implicit emotional drives evoked by such warnings are still underexplored. Here, we provide experimental data for the use of pictorial health warnings as a reliable strategy for tobacco control. METHODS: Experiment 1 pre-tested nineteen prototypes of pictorial warnings to screen for their emotional impact. Participants (n = 338) were young adults balanced in gender, smoking status and education. Experiment 2 (n = 63) tested pictorial warnings (ten) that were stamped on packs. We employed an innovative set-up to investigate the impact of the warnings on the ordinary attitude of packs' manipulation, and quantified judgments of warnings' emotional strength and efficacy against smoking. FINDINGS: Experiment 1 revealed that women judged the warning prototypes as more aversive than men, and smokers judged them more aversive than non-smokers. Participants with lower education judged the prototypes more aversive than participants with higher education. Experiment 2 showed that stamped warnings antagonized the appeal of the brands by imposing a cost to manipulate the cigarette packs, especially for smokers. Additionally, participants' judgments revealed that the more aversive a warning, the more it is perceived as effective against smoking. CONCLUSIONS: Health warning labels are one of the key components of the integrated approach to control the global tobacco epidemic. The evidence presented in this study adds to the understanding of how implicit responses to pictorial warnings may contribute to behavioral change. Descriptors Links Book Title Database Publisher Data Source Authors Volchan,E., David,I.A., Tavares,G., Nascimento,B.M., Oliveira,J.M., Gleiser,S., Szklo,A., Perez,C., Cavalcante,T., Pereira,M.G., Oliveira,L. Original/Translated Title URL Date of Electronic 20130815 PMCID PMC3744501 Editors
Association between serum cholesterol and bone mineral density	2009	Institute of Bone and Joint Research, Kolling Institute, Royal North Shore Hospital, University of Sydney, Australia. jmakovey@med.usyd.edu.au	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Bone Periodical, Abbrev. Bone Pub Date Free Form Feb Volume 44 Issue 2 Start Page 208 Other Pages 213 Notes LR: 20131121; JID: 8504048; 0 (Cholesterol, HDL); 0 (Cholesterol, LDL); 0 (Triglycerides); 97C5T2UQ7J (Cholesterol); 2008/05/29 [received]; 2008/08/14 [revised]; 2008/09/26 [accepted]; 2008/10/17 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1873-2763; 1873-2763 Accession Number PMID: 18983946 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; Twin Study; IM DOI 10.1016/j.bone.2008.09.020 [doi] Output Language Unknown(0) PMID 18983946 Abstract BACKGROUND: Hypercholesterolaemia has been associated with low bone mineral density (BMD) in some but not all studies. OBJECTIVES: To examine the influence of age, menopausal status and hormone replacement therapy (HRT) on the relationship between serum cholesterol and BMD in women. PATIENTS AND MEASUREMENTS: 497 female participants (age range 20-81) comprising 224 premenopausal and 273 postmenopausal women (156 on HRT and 117 no HRT) underwent measurements of bone mineral density (BMD) and serum lipid profile. RESULTS: Total serum cholesterol (TC) and low density lipoprotein (LDL) levels were higher and lumbar spine BMD was lower in postmenopausal women not taking HRT compared to those taking HRT. TC and LDL were negatively associated with BMD at all measured sites among postmenopausal women not taking HRT in univariate regression analysis (all p<0.05). High density lipoprotein (HDL) had inverse relationships with BMD at all sites in pre-menopausal women and those who were exposed to HRT (p<0.05). In fully adjusted regression models the relationships between TC and BMD remained significant at the lumbar spine and whole body (p<0.05) and between LDL and lumbar spine BMD only (p<0.05). For subjects in the other groups, no significant associations between TC or LDL and BMD were found. Significant interactions between total cholesterol and LDL levels with HRT were detected among post-menopausal women in the regression analyses (all p<0.05). No such interactions were found between HDL levels and HRT. CONCLUSION: There is a modest inverse relationship between lumbar spine and whole body BMD and serum TC and LDL levels and in post-menopausal women and HDL in pre-menopausal women. HRT use appears to modify these relationships. The mechanisms of this relationship require further study. Descriptors Adult, Aged, Aged, 80 and over, Bone Density/physiology, Cholesterol/blood, Cholesterol, HDL/blood, Cholesterol, LDL/blood, Female, Humans, Lumbar Vertebrae/physiology, Middle Aged, Regression Analysis, Triglycerides/blood Links Book Title Database Publisher Data Source Authors Makovey,J., Chen,J. S., Hayward,C., Williams,F. M., Sambrook,P. N. Original/Translated Title URL Date of Electronic 20081017 PMCID Editors
A 1:1 co-crystal of the herbicide triflusulfuron-methyl and its degradation product triazine amine	2011	Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164SC, A-1060 Vienna, Austria.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 1-Sep Volume 67 Issue Pt 9 Start Page o2321 Other Pages 2 Notes LR: 20130228; JID: 101089178; OID: NLM: PMC3200658; 2011/07/05 [received]; 2011/08/04 [accepted]; 2011/08/11 [epublish]; ppublish Place of Publication England ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 22058947 Language eng SubFile Journal Article DOI 10.1107/S1600536811031631 [doi] Output Language Unknown(0) PMID 22058947 Abstract The herbicide triflusulfuron-methyl (systematic name: methyl 2-{[4-dimethyl-amino-6-(2,2,2-trifluoro-eth-oxy)-1,3,5-triazin-2-yl]carbamoylsulf amo-yl}-3-methyl-benzoate) and its degradation product triazine amine [systematic name: 2-amino-4-dimethyl-amino-6-(2,2,2-trifluoro-eth-oxy)-1,3,5-triazine] form a triclinic 1:1 co-crystal of the title compound, C(7)H(10)F(3)N(5)O.C(17)H(19)F(3)N(6)O(6)S, in which its two components are connected via a pair of complementary N-Hcdots, three dots, centeredN hydrogen bonds, similar to the monoclinic crystal structure of the parent compound triflusulfuron-methyl [Mereiter (2011 ). Acta Cryst. E67, o1778-o1779] in which a pair of mol-ecules related by a twofold axis are linked by two N-Hcdots, three dots, centeredN bonds. The triflusulfuron-methyl mol-ecules of both crystal structures are similar in geometric parameters and conformation, which is due to stiffening by a short intra-molecular N-Hcdots, three dots, centeredN bond [Ncdots, three dots, centeredN = 2.620 (4) A] and an intra-molecular dipole-dipole inter-action between the sulfamide and the carboxyl moieties, with O(s)cdots, three dots, centeredC(c) = 2.802 (5) A and O(c)cdots, three dots, centeredN(s) = 2.846 (4) A. Inter-molecular N-Hcdots, three dots, centeredO hydrogen bonds and slipped pi-pi stacking inter-actions between the diamino-triazine moieties [perpendicular distances of 3.25 A within hydrogen-bonded tetra-mers and 3.27 A between adjacent tetra-mers] link the two constituents of the co-crystal into columns parallel to the a axis. An intra-molecular C-Hcdots, three dots, centeredO hydrogen bond occurs in the triflusulfuron-methyl mol-ecule and inter-molecular C-Hcdots, three dots, centeredO inter-actions between triflusulfuron-methyl mol-ecules occur in the crystal structure. In the triflusulfuron-methyl molecule the dihedral angle between the least-squares planes of the two rings is 75.8 (1) degrees . In the triazine molecule, the CF(3) group is partly orientationally disordered. Descriptors Links Book Title Database Publisher Data Source Authors Mereiter,K. Original/Translated Title URL Date of Electronic 20110811 PMCID PMC3200658 Editors

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