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Ultrasound elastomicroscopy using water jet and osmosis loading: potentials for assessment for articular cartilage.	2006	Zheng, Y.P., Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China. <ypzheng@ieee.org>	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Ultrasonics Periodical, Abbrev. Ultrasonics Pub Date Free Form / Volume 44 Suppl 1 Issue Start Page e203; 209 Other Pages e203; 209 Notes Place of Publication ISSN/ISBN 0041-624X Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Research in elasticity imaging typically relies on 1-10 MHz ultrasound. Elasticity imaging at these frequencies can provide strain maps with a resolution in the order of millimeters, but this is not sufficient for applications to skin, articular cartilage, or other fine structures. In this paper, we introduced two methods of ultrasound elastomicroscopy using water jet and osmosis loading for imaging the elasticity of biological soft tissues with high resolutions. In the first system, the specimens were compressed using water jet compression. A water jet was used to couple a focused 20 MHz ultrasound beam into the specimen and meanwhile served as a "soft" indenter. Because there was no additional attenuation when propagating from the ultrasound transducer to the specimen, the ultrasound signal with high signal-to-noise ratio could be collected from the specimens simultaneously with compressing process. The compression was achieved by adjusting the water flow. The pressure measured inside the water pipe and that on the specimen surface was calibrated. This system was easily to apply C-scan over sample surfaces. Experiments on the phantoms showed that this water jet indentation method was reliable to map the tissue stiffness distribution. Results of 1D and 2D scanning on phantoms with different stiffness are reported. In the second system, we used osmotic pressure caused by the ion concentration change in the bathing solutions for the articular cartilage to deform them. When bovine articular cartilage specimens were immerged in solutions with different salt concentration, a 50 MHz focused ultrasound beam was used to monitor the dynamic swelling or shrinkage process. Results showed that the system could reliably map the strain distribution induced by the osmotic loading. We extract intrinsic layered material parameters of the articular cartilage using a triphasic model. In addition to biological tissues, these systems have potential applications for the assessment of bioengineered tissues, biomaterials with fine structures, or some engineering materials. Further studies are necessary to fully realize the potentials of these two new methods. Descriptors diagnostic agent, water, acoustic microscopy, algorithm, animal, article, articular cartilage, biological model, bovine, computer assisted diagnosis, computer simulation, echography, elasticity, evaluation study, feasibility study, image enhancement, image quality, devices, mechanical stress, methodology, osmosis, physiology, reproducibility, sensitivity and specificity, three dimensional imaging Links Book Title Database MEDLINE Publisher Data Source Embase Authors Zheng,Y. P., Lu,M. H., Wang,Q. Original/Translated Title URL Date of Electronic PMCID Editors
Ultrasound detection of vascular decompression bubbles: the influence of new technology and considerations on bubble load	2014	SLB Consulting, C/O The Barn, Manor House Wynd, Winton, Cumbria, CA17 4HL, UK, Phone: +44-(0)771-442-2042, E-mail: lesley@chapelclose20.fsnet.co.uk.; Department of Environmental Physiology, School of Technology and Health, Royal Institute of Technology, S	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Diving and hyperbaric medicine Periodical, Abbrev. Diving.Hyperb.Med. Pub Date Free Form Mar Volume 44 Issue 1 Start Page 35 Other Pages 44 Notes LR: 20141212; JID: 101282742; OTO: NOTNLM; 2013/08/02 [received]; 2014/01/26 [accepted]; ppublish Place of Publication Australia ISSN/ISBN 1833-3516; 1833-3516 Accession Number PMID: 24687484 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; Review; IM DOI Output Language Unknown(0) PMID 24687484 Abstract INTRODUCTION: Diving often causes the formation of 'silent' bubbles upon decompression. If the bubble load is high, then the risk of decompression sickness (DCS) and the number of bubbles that could cross to the arterial circulation via a pulmonary shunt or patent foramen ovale increase. Bubbles can be monitored aurally, with Doppler ultrasound, or visually, with two dimensional (2D) ultrasound imaging. Doppler grades and imaging grades can be compared with good agreement. Early 2D imaging units did not provide such comprehensive observations as Doppler, but advances in technology have allowed development of improved, portable, relatively inexpensive units. Most now employ harmonic technology; it was suggested that this could allow previously undetectable bubbles to be observed. METHODS: This paper provides a review of current methods of bubble measurement and how new technology may be changing our perceptions of the potential relationship of these measurements to decompression illness. Secondly, 69 paired ultrasound images were made using conventional 2D ultrasound imaging and harmonic imaging. Images were graded on the Eftedal-Brubakk (EB) scale and the percentage agreement of the images calculated. The distribution of mismatched grades was analysed. RESULTS: Fifty-four of the 69 paired images had matching grades. There was no significant difference in the distribution of high or low EB grades for the mismatched pairs. CONCLUSIONS: Given the good level of agreement between pairs observed, it seems unlikely that harmonic technology is responsible for any perceived increase in observed bubble loads, but it is probable that our increasing use of 2D ultrasound to assess dive profiles is changing our perception of 'normal' venous and arterial bubble loads. Methods to accurately investigate the load and size of bubbles developed will be helpful in the future in determining DCS risk. Descriptors Links Book Title Database Publisher Data Source Authors Blogg,S.L., Gennser,M., Mollerlokken,A., Brubakk,A.O. Original/Translated Title URL Date of Electronic PMCID Editors
Ultrafine particle emissions from waterpipes	2007		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tob Control Periodical, Abbrev. Tob.Control Pub Date Free Form Volume 16 Issue 6 Start Page 390 Other Pages 3 Notes ID: 18048615 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract OBJECTIVES: Ultrafine particle emissions from waterpipes and their impact on human health have not been extensively studied. The aim of this study was to characterise the inhalation pattern of waterpipe smokers, and (a) construct apparatus to simulate waterpipe smoking in the laboratory, and (b) characterise mainstream emissions from waterpipes under different smoking conditions. METHODS: Real life waterpipe smoking patterns were first measured with a spirometer. The average smoking pattern was then mechanically simulated in apparatus. Total particle number concentrations were determined with a condensation particle counter (CPC) for particles between 0.02 microm and 1 microm (P-Trak UPC, Model 8525, TSI) and the particle size fraction was determined with a differential mobility analyser (DMA) for particles from 0.01 microm to 0.5 microm. This instrument was coupled with a laser particle spectrometer for particles between 0.35 microm and 10 microm (Wide Range Particle Spectrometer, Model 1000XP, MSC Corp). Carbon monoxide levels were determined with an electrochemical sensor (Q-Trak monitor, Model 8554, TSI). RESULTS: The tidal volume of an average waterpipe breath of 5 seconds was found to be 1 (SD 0.47) litre. The intervals between breaths on average were 25.5 (SD 10.2) seconds. Particle number concentrations of ultrafine particles in mainstream smoke during waterpipe smoking ranged up to 70 x 10(9) particles per litre. The median diameter of the particles in a full smoking set with charcoal, tobacco and water was 0.04 microm. Smoke from the heated tobacco contributed to particles in the size range between 0.01 microm and 0.2 microm. The glowing piece of charcoal only contributed to particles smaller than 0.05 microm. CONCLUSIONS: Waterpipe smoking emits large amounts of ultrafine particles. With regard to particle emissions, smoking waterpipes may carry similar health risks to smoking cigarettes. Descriptors Inhalation Exposure/analysis, Smoking/adverse effects, Adult, Air Pollution, Indoor/analysis, Carbon Monoxide/analysis, Female, Humans, Male, Particle Size, Switzerland, Tidal Volume, Tobacco Smoke Pollution/analysis, Water Links http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807191/?tool=pubmed Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Monn,Ch, Kindler,Ph, Meile,A., BrÃ¤ndli,O. Original/Translated Title URL Date of Electronic PMCID Editors
Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus	2015	Departamento de Ciencias Farmaceuticas, Centro de Ciencias da Saude, Laboratorio de Farmacologia do Trato Gastrintestinal, Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB, Brazil. leoniab@uol.com.br.; Departamento de Fisiologia e Biofisica, Instit	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC complementary and alternative medicine Periodical, Abbrev. BMC Complement.Altern.Med. Pub Date Free Form 29-Oct Volume 15 Issue Start Page 391 Other Pages 015-0923-x Notes LR: 20151031; JID: 101088661; OID: NLM: PMC4625929; 2014/11/14 [received]; 2015/10/20 [accepted]; 2015/10/29 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1472-6882; 1472-6882 Accession Number PMID: 26511617 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1186/s12906-015-0923-x [doi] Output Language Unknown(0) PMID 26511617 Abstract BACKGROUND: Syngonanthus arthrotrichus and Syngonanthus bisulcatus, currently known for Comanthera aciphylla (Bong.) L.R.Parra & Giul. and Comanthera bisulcata (Koern.) L.R. Parra & Giul, popularly known in Brazil as "sempre-vivas," are plants from the family Eriocaulaceae. They are found in the states of Minas Gerais and Bahia. The species are known to be rich in flavonoids to which their gastroprotective activity has been attributed. In this research, experimental protocols were performed to elucidate the associated mechanisms of action. METHODS: The activity was evaluated using induced gastric ulcer models (acetic acid and ethanol-induced gastric lesions in NEM or L-NAME pre-treated mice, and by ischemia/reperfusion). Antioxidant enzymes, serum somatostatin, and gastrin were also evaluated. RESULTS: In chronic gastric ulcers, a single daily oral dose of Sa-FRF or Sb-FRF (100 mg/kg body wt.) for 14 consecutive days accelerated ulcer healing to an extent similar to that seen with an equal dose of cimetidine. The pre-treatment of mice with NEM (N-ethylmaleimide) or L-NAME (N-nitro-L-arginine) abolished the protective activity of Sa-FRF, Sa-FDF, Sb-FDF and Sb-FRF or Sa-FRF and Sb-FRF, respectively, which indicates that antioxidant compounds and nitric oxide synthase activity are involved in the gastroprotective. Sa-FRF and Sb-FRF (100 mg/kg p.o) protected the gastric mucosa against ulceration that was induced by ischemia/reperfusion (72 and 76 %, respectively). It also decreased lipid peroxidation and restored total thiols in the gastric wall of mice that had been treated with ethanol. When administered to rats submitted to ethanol-induced gastric lesions, Sa-FRF and Sb-FRF (100 mg/kg, p.o.) increased the somatostatin serum levels, while the gastrin serum levels were proportionally decreased. CONCLUSIONS: The results indicate significant healing effects and gastroprotective activity for the Sa-FRF and Sb-FRF, which probably involves the participation of SH groups, nitric oxide (NO), the antioxidant system, somatostatin, and gastrin. All are integral parts of the gastrointestinal mucosa's cytoprotective mechanisms against aggressive factors. Descriptors Links Book Title Database Publisher Data Source Authors Batista,L.M., Lima,G.R., De Almeida,A.B., Magri Lde,P., Calvo,T.R., Ferreira,A.L., Pellizzon,C.H., Hiruma-Lima,C.A., Vilegas,W., Sano,P.T., Brito,A.R. Original/Translated Title URL Date of Electronic 20151029 PMCID PMC4625929 Editors
UK smoke-free legislation: changes in PM2.5 concentrations in bars in Scotland, England, and Wales	2010	Scottish Centre for Indoor Air, Liberty Safe Work Research Centre, Population Health Sciences, University of Aberdeen, Aberdeen AB25 2ZP, UK. sean.semple@abdn.ac.uk	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Annals of Occupational Hygiene Periodical, Abbrev. Ann.Occup.Hyg. Pub Date Free Form Apr Volume 54 Issue 3 Start Page 272 Other Pages 280 Notes LR: 20140730; GR: Department of Health/United Kingdom; JID: 0203526; 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); 2010/02/19 [aheadofprint]; 2010/03/01 [aheadofprint]; 2010/03/02 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1475-3162; 0003-4878 Accession Number PMID: 20172917 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/annhyg/mep094 [doi] Output Language Unknown(0) PMID 20172917 Abstract OBJECTIVE: Evaluate the effect of smoke-free legislation on fine particulate [particulate matter <2.5 microm in diameter (PM(2.5))] air pollution levels in bars in Scotland, England, and Wales. DESIGN: Air quality was measured in 106 randomly selected bars in Scotland, England, and Wales before and after the introduction of smoking restrictions. METHODS: PM(2.5) concentrations were measured covertly for 30-min periods before smoke-free legislation was introduced, again at 1-2 months post-ban (except Wales) and then at 12-months post-baseline (except Scotland). In Scotland and England, overt measurements were carried out to assess bar workers' full-shift personal exposures to PM(2.5). Postcode data were used to determine socio-economic status of the bar location. RESULTS: PM(2.5) levels prior to smoke-free legislation were highest in Scotland (median 197 microg m(-3)), followed by Wales (median 184 microg m(-3)) and England (median 92 microg m(-3)). All three countries experienced a substantial reduction in PM(2.5) concentrations following the introduction of the legislation with the median reduction ranging from 84 to 93%. Personal exposure reductions were also within this range. There was evidence that bars located in more deprived postcodes had higher PM(2.5) levels prior to the legislation. CONCLUSIONS: Prior to legislation PM(2.5) concentrations within bars across the UK were much higher than the 65 microg m(-3) 'unhealthy' threshold for outdoor air quality as set by the US Environmental Protection Agency. Concentrations in Scottish and Welsh bars were, on average, two or more times greater than in English bars for which seasonal influences may be responsible. Legislation in all three countries produced improvements in indoor air quality that are consistent with other international studies. Descriptors Air Pollution, Indoor/analysis/statistics & numerical data, Environmental Monitoring/methods/statistics & numerical data, Great Britain, Humans, Occupational Exposure/analysis/prevention & control/statistics & numerical data, Particle Size, Particulate Matter/analysis, Program Evaluation, Residence Characteristics/statistics & numerical data, Restaurants, Seasons, Smoking/legislation & jurisprudence/prevention & control, Socioeconomic Factors, Time Factors, Tobacco Smoke Pollution/analysis/legislation & jurisprudence/statistics & numerical data Links Book Title Database Publisher Data Source Authors Semple,S., van Tongeren,M., Galea,K. S., MacCalman,L., Gee,I., Parry,O., Naji,A., Ayres,J. G. Original/Translated Title URL Date of Electronic 20100219 PMCID Editors
U.S. hookah tobacco smoking establishments advertised on the internet	2012		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Am J Prev Med Periodical, Abbrev. Am.J.Prev.Med. Pub Date Free Form Volume 42 Issue 2 Start Page 150 Other Pages 6 Notes ID: 22261211 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract BACKGROUND: Establishments dedicated to hookah tobacco smoking recently have proliferated and helped introduce hookah use to U.S. communities. PURPOSE: To conduct a comprehensive, qualitative assessment of websites promoting these establishments. METHODS: In June 2009, a systematic search process was initiated to access the universe of websites representing major hookah tobacco smoking establishments. In 2009-2010, codebook development followed an iterative paradigm involving three researchers and resulted in a final codebook consisting of 36 codes within eight categories. After two independent coders had nearly perfect agreement (Cohen's Îº = 0.93) on double-coding the data in the first 20% of sites, the coders divided the remaining sites and coded them independently. A thematic approach to the synthesis of findings and selection of exemplary quotations was used. RESULTS: The search yielded a sample of 144 websites originating from states in all U.S. regions. Among the hookah establishments promoted on the websites, 79% served food and 41% served alcohol. Of the websites, none required age verification, Descriptors Links Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Primack,Brian A., Rice,Kristen R., Shensa,Ariel, Carroll,Mary V., DePenna,Erica J., Nakkash,Rima, Barnett,Tracey E. Original/Translated Title URL Date of Electronic PMCID Editors
Typing of Pseudomonas aeruginosa in patients injured by burns	1974	Abt. Verbrenn. Plast. Handchir., Berufsgenossenschaftl. Unfallklin., Ludwigshafen/Oggersheim	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Medizinische Klinik Periodical, Abbrev. Med.Klin. Pub Date Free Form 1974/ Volume 69 Issue 8 Start Page 346 Other Pages 349 Notes Place of Publication ISSN/ISBN 0723-5003 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract 8,464 isolates from patients suffering from burns were typed. In 18,852 wound smears of 697 injured patients, P. aeruginosa was found in 7,650 cases. Dominating were the O groups 5 and 13. In 2,299 smears, however, taken from water pipes, groups 4 and 5 or 3, resp., dominated. Bacterial cultures taken from the environment of patients included P. aeruginosa in only 6.7% mostly type 5. Pseudomonas strains were never resistant to wide spectrum antibiotics. Sensibility was found mostly against Refobacin, carbenicillin, and colistin. Descriptors burn, epidemiology, hospital infection, in vitro study, Pseudomonas aeruginosa Links Book Title DIE SEROTYPISIERUNG VON PSEUDOMONAS AERUGINOSA STAMMEN BEI BRANDVERLETZTEN Database Embase; MEDLINE Publisher Data Source Embase Authors Zellner,P. R., Metzger,E. Original/Translated Title URL Date of Electronic PMCID Editors
Types of tobacco consumption and the oral microbiome in the United Arab Emirates Healthy Future (UAEHFS) Pilot Study	2018	Public Health Research Center, New York University Abu Dhabi, Abu Dhabi, UAE.; Public Health Research Center, New York University Abu Dhabi, Abu Dhabi, UAE.; Department of Population Health, New York University School of Medicine, New York, USA.(TRUNCATED	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Scientific reports Periodical, Abbrev. Sci.Rep. Pub Date Free Form 27-Jul Volume 8 Issue 1 Start Page 11327 Other Pages 018-29730-x Notes LR: 20181114; JID: 101563288; 2017/11/23 00:00 [received]; 2018/06/27 00:00 [accepted]; 2018/07/29 06:00 [entrez]; 2018/07/29 06:00 [pubmed]; 2018/07/29 06:00 [medline]; epublish Place of Publication England ISSN/ISBN 2045-2322; 2045-2322 Accession Number PMID: 30054546 Language eng SubFile Journal Article DOI 10.1038/s41598-018-29730-x [doi] Output Language Unknown(0) PMID 30054546 Abstract Cigarette smoking alters the oral microbiome; however, the effect of alternative tobacco products remains unclear. Middle Eastern tobacco products like dokha and shisha, are becoming globally widespread. We tested for the first time in a Middle Eastern population the hypothesis that different tobacco products impact the oral microbiome. The oral microbiome of 330 subjects from the United Arab Emirates Healthy Future Study was assessed by amplifying the bacterial 16S rRNA gene from mouthwash samples. Tobacco consumption was assessed using a structured questionnaire and further validated by urine cotinine levels. Oral microbiome overall structure and specific taxon abundances were compared, using PERMANOVA and DESeq analyses respectively. Our results show that overall microbial composition differs between smokers and nonsmokers (p = 0.0001). Use of cigarettes (p = 0.001) and dokha (p = 0.042) were associated with overall microbiome structure, while shisha use was not (p = 0.62). The abundance of multiple genera were significantly altered (enriched/depleted) in cigarette smokers; however, only Actinobacillus, Porphyromonas, Lautropia and Bifidobacterium abundances were significantly changed in dokha users whereas no genera were significantly altered in shisha smokers. For the first time, we show that smoking dokha is associated to oral microbiome dysbiosis, suggesting that it could have similar effects as smoking cigarettes on oral health. Descriptors Links Book Title Database Publisher Data Source Authors Valles,Y., Inman,C.K., Peters,B.A., Ali,R., Wareth,L.A., Abdulle,A., Alsafar,H., Anouti,F.A., Dhaheri,A.A., Galani,D., Haji,M., Hamiz,A.A., Hosani,A.A., Houqani,M.A., Junaibi,A.A., Kazim,M., Kirchhoff,T., Mahmeed,W.A., Maskari,F.A., Alnaeemi,A., Oumeziane,N., Ramasamy,R., Schmidt,A.M., Weitzman,M., Zaabi,E.A., Sherman,S., Hayes,R.B., Ahn,J. Original/Translated Title URL Date of Electronic 20180727 PMCID PMC6063860 Editors
Type of tobacco product used: are there differences between university and community college students?	2007	Department of Health Education and Behavior, University of Florida, Gainesville 32611-2034, USA. djames@hhp.ufl.edu	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of drug education Periodical, Abbrev. J.Drug Educ. Pub Date Free Form Volume 37 Issue 4 Start Page 379 Other Pages 392 Notes JID: 1300031; ppublish Place of Publication United States ISSN/ISBN 0047-2379; 0047-2379 Accession Number PMID: 18351177 Language eng SubFile Journal Article; IM DOI Output Language Unknown(0) PMID 18351177 Abstract This article describes and compares smoking prevalence, types of tobacco products used, and motivation to quit among college students at universities and community colleges. Data were collected using the Florida Annual College Tobacco Survey (FACTS). Nine universities and eight community colleges participated in the study (n = 4973). Most students (69%) experimented with tobacco. Cigarettes were used more often (57.4%), followed by Black 'N Mild (31.8%), cigars (30.1%), kreteks/bidis (24.1%), smokeless tobacco (13.9%), and pipe (8.9%). University students were more likely than community college students to have tried kreteks/bidis and cigars (p < .05). University students experimented at a significantly earlier age with cigarettes and pipes while community college experimented at a significantly earlier age with cigars and kreteks/bidis (p < .05). The majority of cigarette smokers (62%) were not interested in quitting. The implications for college tobacco education programs are discussed. Descriptors Adult, Female, Health Surveys, Humans, Male, Smoking/epidemiology/trends, Smoking Cessation, Students/statistics & numerical data, Universities Links Book Title Database Publisher Data Source Authors James,D. C., Chen,W. W., Sheu,J. J. Original/Translated Title URL Date of Electronic PMCID Editors
Two men with multiple disabilities carry out an assembly work activity with the support of a technology system	2013	Department of Neuroscience and Sense Organs, University of Bari , 70100 Bari , Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Developmental neurorehabilitation Periodical, Abbrev. Dev.Neurorehabil Pub Date Free Form Oct Volume 16 Issue 5 Start Page 332 Other Pages 339 Notes LR: 20151119; JID: 101304394; ppublish Place of Publication England ISSN/ISBN 1751-8431; 1751-8423 Accession Number PMID: 24020878 Language eng SubFile Case Reports; Journal Article; IM DOI 10.3310/phr04020 [doi] Output Language Unknown(0) PMID 24020878 Abstract OBJECTIVE: To assess whether two persons with multiple disabilities could learn a work activity (i.e., assembling trolley wheels) with the support of a technology system. METHOD: After an initial baseline, the study compared the effects of intervention sessions relying on the technology system (which called the participants to the different workstations and provided feedback and final stimulation) with the effects of intervention sessions carried out without technology. The two types of intervention sessions were conducted according to an alternating treatments design. Eventually, only intervention sessions relying on the technology system were used. RESULTS: Both participants managed to assemble wheels independently during intervention sessions relying on the technology system while they failed during sessions without the system. Their performance was strengthened during the final part of the study, in which only sessions with the system occurred. CONCLUSION: Technology may be critical in helping persons with multiple disabilities manage multi-step work activities. Descriptors Links Book Title Database Publisher Data Source Authors Lancioni,G.E., Singh,N.N., O'Reilly,M.F., Green,V.A., Oliva,D., Campodonico,F. Original/Translated Title URL Date of Electronic PMCID Editors

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