WTS database

Title	Pub Year	Author	SearchLink Sort descending
Thirdhand cigarette smoke in an experimental chamber: evidence of surface deposition of nicotine, nitrosamines and polycyclic aromatic hydrocarbons and de novo formation of NNK	2014	Department of Medicine, University of California, , San Francisco, California, USA.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Mar Volume 23 Issue 2 Start Page 152 Other Pages 159 Notes LR: 20151119; JID: 9209612; 0 (Carcinogens); 0 (Dust); 0 (Nitrosamines); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Tobacco Smoke Pollution); 64091-91-4 (4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone); 6M3C89ZY6R (Nicotine); K5161X06LL (Cotinine); X6 Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 23716171 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1136/tobaccocontrol-2012-050915 [doi] Output Language Unknown(0) PMID 23716171 Abstract BACKGROUND: A growing body of evidence shows that secondhand cigarette smoke undergoes numerous chemical changes after it is released into the air: it can adsorb to indoor surfaces, desorb back into the air and undergo chemical changes as it ages. OBJECTIVES: To test the effects of aging on the concentration of polycyclic aromatic hydrocarbons (PAHs), nicotine and tobacco-specific nitrosamines in cigarette smoke. METHODS: We generated sidestream and mainstream cigarette smoke with a smoking machine, diluted it with conditioned filtered air, and passed it through a 6 m(3) flow reactor with air exchange rates that matched normal residential air exchange rates. We tested the effects of 60 min aging on the concentration of 16 PAHs, nicotine, cotinine and tobacco-specific nitrosamines. We also measured sorption and deposition of nicotine, cotinine and tobacco-specific nitrosamines on materials placed within the flow reactor. RESULTS: We observed mass losses of 62% for PAHs, 72%, for nicotine, 79% for N-nitrosonornicotine and 80% for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Extraction of cotton cloth exposed to smoke yielded nicotine and NNK. The ratio of NNK:nicotine on the exposed cloth was 10-fold higher than that in aerosol samples. CONCLUSIONS: Our data suggest that the majority of the PAHs, nicotine, cotinine and tobacco-specific nitrosamines that are released during smoking in homes and public places deposit on room surfaces. These data give an estimate of the potential for accumulation of carcinogens in thirdhand cigarette smoke. Exposure to PAHs and tobacco-specific nitrosamines, through dermal absorption and inhalation of contaminated dust, may contribute to smoking-attributable morbidity and mortality. Descriptors Links Book Title Database Publisher Data Source Authors Schick,S.F., Farraro,K.F., Perrino,C., Sleiman,M., van de Vossenberg,G., Trinh,M.P., Hammond,S.K., Jenkins,B.M., Balmes,J. Original/Translated Title URL Date of Electronic 20130528 PMCID Editors
IncI1/ST3 and IncN/ST1 plasmids drive the spread of blaTEM-52 and blaCTX-M-1/-32 in diverse Escherichia coli clones from different piggeries	2013	REQUIMTE, Laboratorio de Microbiologia, Faculdade de Farmacia, Universidade do Porto, Porto, Portugal.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of antimicrobial chemotherapy Periodical, Abbrev. J.Antimicrob.Chemother. Pub Date Free Form Oct Volume 68 Issue 10 Start Page 2245 Other Pages 2248 Notes JID: 7513617; EC 3.5.2.- (TEM-52 beta-lactamase); EC 3.5.2.- (beta-lactamase TEM-3); EC 3.5.2.6 (beta-Lactamases); EC 3.5.2.6 (beta-lactamase CTX-M-32, E coli); OTO: NOTNLM; 2013/05/29 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1460-2091; 0305-7453 Accession Number PMID: 23719233 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/jac/dkt187 [doi] Output Language Unknown(0) PMID 23719233 Abstract OBJECTIVES: The spread of ESBL-producing Enterobacteriaceae among food animals/products has raised concerns about their possible transmission through the food chain. We aimed to characterize piggeries (pigs, piggery environments) as reservoirs of TEM-52- and CTX-M-encoding plasmids and clones. METHODS: Forty-three samples from five Portuguese intensive production farms were studied (2006-07). Twenty-two ESBL-producing (13 TEM-52, 6 CTX-M-32, 3 CTX-M-1) Escherichia coli isolates from healthy pigs, feed and liquid manure were further characterized. Standard methods were used for clonal (PFGE, MLST) and plasmid (S1-PFGE, replicon typing, pMLST, RFLP) analysis. PCR and sequencing were used for analysis of blaCTX-M genetic context and plasmid-mediated quinolone resistance genes. RESULTS: TEM-52 (n = 13/22; 59%), CTX-M-32 (n = 6/22; 27%) and CTX-M-1 (n = 3/22; 14%) were identified in feed (36%), swine faeces (36%), swine hide (9%) and liquid manure (18%) at different farms. Diverse phylogenetic groups and clones were identified among TEM-52 (7 A, 3 B1, 2 B2, 1 D; 8 clones)-producing, CTX-M-1 (1 A, 1 B1, 1 D; 3 clones)-producing and CTX-M-32 (4 A, 2 B1; 4 clones)-producing isolates. However, the ST10 clonal complex was frequent among TEM-52 (n = 6) and CTX-M-32 (n = 3) producers. blaTEM-52 and blaCTX-M-1/-32 genes were identified within epidemic IncI1/ST3 and IncN/ST1 plasmid variants, respectively. CONCLUSIONS: We report for the first time a piggery reservoir for blaTEM-52. The spread of blaTEM-52 and blaCTX-M-1/-32 within and/or between different piggeries was mostly associated with epidemic plasmids and clones previously identified in humans and other animal hosts in different EU countries, highlighting possible distribution along the food chain. Descriptors Links Book Title Database Publisher Data Source Authors Rodrigues,C., Machado,E., Peixe,L., Novais,A. Original/Translated Title URL Date of Electronic 20130529 PMCID Editors
Tobacco use, smoking quit rates, and socioeconomic patterning among men and women: a cross-sectional survey in rural Andhra Pradesh, India	2014	Harvard University, Cambridge, MA, USA djcorsi@hsph.harvard.edu.; Harvard School of Public Health, Boston, MA, USA.; Simon Fraser University, Vancouver, BC, Canada.; McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada.; McMaster Univers	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full European journal of preventive cardiology Periodical, Abbrev. Eur.J.Prev.Cardiol. Pub Date Free Form Oct Volume 21 Issue 10 Start Page 1308 Other Pages 1318 Notes CI: (c) The European Society of Cardiology 2013; JID: 101564430; OTO: NOTNLM; 2013/05/30 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 2047-4881; 2047-4873 Accession Number PMID: 23723329 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1177/2047487313491356 [doi] Output Language Unknown(0) PMID 23723329 Abstract BACKGROUND: Tobacco use is common in India and a majority of users are in rural areas. We examine tobacco use and smoking quit rates along gender and socioeconomic dimensions in rural Andhra Pradesh. DESIGN AND METHODS: Data come from a cross-sectional survey. Markers of socioeconomic status (SES) were education, occupation, and income. Regression analyses were undertaken to examine determinants of current smoking, smoking quit rates, tobacco use by type (cigarettes, bidis, and chewing), and quantity consumed (number per day, pack-years). RESULTS: The weighted prevalence of current smoking and tobacco chewing was higher in men (50.3%, 95% confidence interval, CI, 48.1-52.6 and 5.0%, 95% CI 4.1-5.9, respectively) compared with women (4.8%, 95% CI 3.9-5.7 and 1.0%, 95% CI 0.6-1.4, respectively) and higher among older age groups. The quit rate was higher in women (45.5%, 95% CI 38.7-52.2) compared to men (18.8%, 95% CI 16.7-20.9). Illiterate individuals were more likely to be current smokers of any type compared to those with secondary/higher education (odds ratio, OR, 3.25, 95% CI 2.54-4.16), although cigarette smoking was higher in men of high SES. Smoking quit rates were positively associated with SES (OR 2.56, 95% CI 1.76-3.71) for secondary/higher education vs. illiterates. Level of consumption increased with SES and those with secondary/higher education smoked an additional 1.93 (95% CI 1.08-2.77) cigarettes or bidis per day and had an additional 1.87 (95% CI 0.57-3.17) pack-years vs. illiterates. CONCLUSIONS: The social gradients in cigarette smoking and level of consumption contrasted those for indigenous forms of tobacco (bidi smoking and chewing). International prevention and cessation initiatives designed at modifying Western-style cigarette usage will need to be tailored to the social context of rural Andhra Pradesh to effectively influence the use of cigarettes and equally harmful indigenous forms of tobacco. Descriptors Links Book Title Database Publisher Reprints and permissions: sagepub.co.uk/journalsPermissions.nav Data Source Authors Corsi,D.J., Subramanian,S.V., Lear,S.A., Teo,K.K., Boyle,M.H., Raju,P.K., Joshi,R., Neal,B., Chow,C.K. Original/Translated Title URL Date of Electronic 20130530 PMCID Editors
Pharmacological interventions for smoking cessation: an overview and network meta-analysis	2013	Department of Primary Care Health Sciences, University of Oxford, Oxford, UK. kate.cahill@phc.ox.ac.uk.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Cochrane database of systematic reviews Periodical, Abbrev. Cochrane Database Syst.Rev. Pub Date Free Form 31-May Volume (5):CD009329. doi Issue 5 Start Page CD009329 Other Pages Notes LR: 20160602; JID: 100909747; 0 (Alkaloids); 0 (Antidepressive Agents, Second-Generation); 0 (Azocines); 0 (Benzazepines); 0 (Nicotinic Agonists); 0 (Quinolizines); 0 (Quinoxalines); 01ZG3TPX31 (Bupropion); 53S5U404NU (cytisine); BL03SY4LXB (Nortriptyline Place of Publication England ISSN/ISBN 1469-493X; 1361-6137 Accession Number PMID: 23728690 Language eng SubFile Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; IM DOI 10.1002/14651858.CD009329.pub2 [doi] Output Language Unknown(0) PMID 23728690 Abstract BACKGROUND: Smoking is the leading preventable cause of illness and premature death worldwide. Some medications have been proven to help people to quit, with three licensed for this purpose in Europe and the USA: nicotine replacement therapy (NRT), bupropion, and varenicline. Cytisine (a treatment pharmacologically similar to varenicline) is also licensed for use in Russia and some of the former socialist economy countries. Other therapies, including nortriptyline, have also been tested for effectiveness. OBJECTIVES: How do NRT, bupropion and varenicline compare with placebo and with each other in achieving long-term abstinence (six months or longer)? How do the remaining treatments compare with placebo in achieving long-term abstinence? How do the risks of adverse and serious adverse events (SAEs) compare between the treatments, and are there instances where the harms may outweigh the benefits? METHODS: The overview is restricted to Cochrane reviews, all of which include randomised trials. Participants are usually adult smokers, but we exclude reviews of smoking cessation for pregnant women and in particular disease groups or specific settings. We cover nicotine replacement therapy (NRT), antidepressants (bupropion and nortriptyline), nicotine receptor partial agonists (varenicline and cytisine), anxiolytics, selective type 1 cannabinoid receptor antagonists (rimonabant), clonidine, lobeline, dianicline, mecamylamine, Nicobrevin, opioid antagonists, nicotine vaccines, and silver acetate. Our outcome for benefit is continuous or prolonged abstinence at least six months from the start of treatment. Our outcome for harms is the incidence of serious adverse events associated with each of the treatments. We searched the Cochrane Database of Systematic Reviews (CDSR) in The Cochrane Library, for any reviews with 'smoking' in the title, abstract or keyword fields. The last search was conducted in November 2012. We assessed methodological quality using a revised version of the AMSTAR scale. For NRT, bupropion and varenicline we conducted network meta-analyses, comparing each with the others and with placebo for benefit, and varenicline and bupropion for risks of serious adverse events. MAIN RESULTS: We identified 12 treatment-specific reviews. The analyses covered 267 studies, involving 101,804 participants. Both NRT and bupropion were superior to placebo (odds ratios (OR) 1.84; 95% credible interval (CredI) 1.71 to 1.99, and 1.82; 95% CredI 1.60 to 2.06 respectively). Varenicline increased the odds of quitting compared with placebo (OR 2.88; 95% CredI 2.40 to 3.47). Head-to-head comparisons between bupropion and NRT showed equal efficacy (OR 0.99; 95% CredI 0.86 to 1.13). Varenicline was superior to single forms of NRT (OR 1.57; 95% CredI 1.29 to 1.91), and to bupropion (OR 1.59; 95% CredI 1.29 to 1.96). Varenicline was more effective than nicotine patch (OR 1.51; 95% CredI 1.22 to 1.87), than nicotine gum (OR 1.72; 95% CredI 1.38 to 2.13), and than 'other' NRT (inhaler, spray, tablets, lozenges; OR 1.42; 95% CredI 1.12 to 1.79), but was not more effective than combination NRT (OR 1.06; 95% CredI 0.75 to 1.48). Combination NRT also outperformed single formulations. The four categories of NRT performed similarly against each other, apart from 'other' NRT, which was marginally more effective than NRT gum (OR 1.21; 95% CredI 1.01 to 1.46). Cytisine (a nicotine receptor partial agonist) returned positive findings (risk ratio (RR) 3.98; 95% CI 2.01 to 7.87), without significant adverse events or SAEs. Across the 82 included and excluded bupropion trials, our estimate of six seizures in the bupropion arms versus none in the placebo arms was lower than the expected rate (1:1000), at about 1:1500. SAE meta-analysis of the bupropion studies demonstrated no excess of neuropsychiatric (RR 0.88; 95% CI 0.31 to 2.50) or cardiovascular events (RR 0.77; 95% CI 0.37 to 1.59). SAE meta-analysis of 14 varenicline trials found no difference between th Descriptors Links Book Title Database Publisher Data Source Authors Cahill,K., Stevens,S., Perera,R., Lancaster,T. Original/Translated Title URL Date of Electronic 20130531 PMCID Editors
The influence of prices on youth tobacco use in India	2014	Moody's Analytics, West Chester, PA;	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Periodical, Abbrev. Nicotine Tob.Res. Pub Date Free Form Jan Volume 16 Suppl 1 Issue Start Page S24 Other Pages 9 Notes JID: 9815751; 2013/06/06 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-994X; 1462-2203 Accession Number PMID: 23743096 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/ntr/ntt041 [doi] Output Language Unknown(0) PMID 23743096 Abstract INTRODUCTION: The tobacco epidemic has been rapidly spreading in many of the poorer nations of the world, including India. Although studies assessing the impact of prices on youth smoking in countries such as the United States are abundant, comparable research on Indian youth has been largely unavailable due to lack of data at the national level. This study aims to bridge this disparity in tobacco research. METHODS: We used data from the Global Youth Tobacco Survey, a national survey among 73,356 youth of age 13-15 years in India, to estimate the price elasticity of tobacco use among Indian youth for three tobacco products: cigarettes, bidi, and gutka. RESULTS: Higher prices can be an effective deterrent to youth tobacco use, irrespective of the form of tobacco. Among the products considered, bidis have the highest price elasticity of participation (-2.70), followed by gutka (0.58) and cigarettes (-0.40). In gender-specific analyses, girls have significantly higher participation price elasticities than boys. CONCLUSION: The results of this study indicate that fiscal measures to increase the price of tobacco products would be effective in curbing the tobacco epidemic in India. Descriptors Links Book Title Database Publisher Data Source Authors Joseph,R.A., Chaloupka,F.J. Original/Translated Title URL Date of Electronic 20130606 PMCID Editors
Opioid antagonists for smoking cessation	2013	Center for Education in Family & Community Medicine, Stanford University, Stanford, California, USA. spdavid@stanford.edu.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Cochrane database of systematic reviews Periodical, Abbrev. Cochrane Database Syst.Rev. Pub Date Free Form 6-Jun Volume (6):CD003086. doi Issue 6 Start Page CD003086 Other Pages Notes LR: 20160602; GR: P50 DA009253/DA/NIDA NIH HHS/United States; GR: P50 DA009253/DA/NIDA NIH HHS/United States; GR: R01 MH083684/MH/NIMH NIH HHS/United States; GR: R01 MH083684/MH/NIMH NIH HHS/United States; JID: 100909747; 0 (Narcotic Antagonists); 36B82AM Place of Publication England ISSN/ISBN 1469-493X; 1361-6137 Accession Number PMID: 23744347 Language eng SubFile Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review; IM DOI 10.1002/14651858.CD003086.pub3 [doi] Output Language Unknown(0) PMID 23744347 Abstract BACKGROUND: The reinforcing properties of nicotine may be mediated through release of various neurotransmitters both centrally and systemically. People who smoke report positive effects such as pleasure, arousal, and relaxation as well as relief of negative affect, tension, and anxiety. Opioid (narcotic) antagonists are of particular interest to investigators as potential agents to attenuate the rewarding effects of cigarette smoking. OBJECTIVES: To evaluate the efficacy of opioid antagonists in promoting long-term smoking cessation. The drugs include naloxone and the longer-acting opioid antagonist naltrexone. SEARCH METHODS: We searched the Cochrane Tobacco Addiction Group Specialised Register for trials of naloxone, naltrexone and other opioid antagonists and conducted an additional search of MEDLINE using 'Narcotic antagonists' and smoking terms in April 2013. We also contacted investigators, when possible, for information on unpublished studies. SELECTION CRITERIA: We considered randomised controlled trials comparing opioid antagonists to placebo or an alternative therapeutic control for smoking cessation. We included in the meta-analysis only those trials which reported data on abstinence for a minimum of six months. We also reviewed, for descriptive purposes, results from short-term laboratory-based studies of opioid antagonists designed to evaluate psycho-biological mediating variables associated with nicotine dependence. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the study population, the nature of the drug therapy, the outcome measures, method of randomisation, and completeness of follow-up. The main outcome measure was abstinence from smoking after at least six months follow-up in patients smoking at baseline. Abstinence at end of treatment was a secondary outcome. We extracted cotinine- or carbon monoxide-verified abstinence where available. Where appropriate, we performed meta-analysis, pooling risk ratios using a Mantel-Haenszel fixed-effect model. MAIN RESULTS: Eight trials of naltrexone met inclusion criteria for meta-analysis of long-term cessation. One trial used a factorial design so five trials compared naltrexone versus placebo and four trials compared naltrexone plus nicotine replacement therapy (NRT) versus placebo plus NRT. Results from 250 participants in one long-term trial remain unpublished. No significant difference was detected between naltrexone and placebo (risk ratio (RR) 1.00; 95% confidence interval (CI) 0.66 to 1.51, 445 participants), or between naltrexone and placebo as an adjunct to NRT (RR 0.95; 95% CI 0.70 to 1.30, 768 participants). The estimate was similar when all eight trials were pooled (RR 0.97; 95% CI 0.76 to 1.24, 1213 participants). In a secondary analysis of abstinence at end of treatment, there was also no evidence of any early treatment effect, (RR 1.03; 95% CI 0.88 to 1.22, 1213 participants). No trials of naloxone or buprenorphine reported abstinence outcomes. AUTHORS' CONCLUSIONS: Based on data from eight trials and over 1200 individuals, there was no evidence of an effect of naltrexone alone or as an adjunct to NRT on long-term smoking abstinence, with a point estimate strongly suggesting no effect and confidence intervals that make a clinically important effect of treatment unlikely. Although further trials might narrow the confidence intervals they are unlikely to be a good use of resources. Descriptors Links Book Title Database Publisher Data Source Authors David,S.P., Lancaster,T., Stead,L.F., Evins,A.E., Prochaska,J.J. Original/Translated Title URL Date of Electronic 20130606 PMCID PMC4038652 Editors
Electronic cigarette use by college students	2013	Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States. ESutfin@wakehealth.edu	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Drug and alcohol dependence Periodical, Abbrev. Drug Alcohol Depend. Pub Date Free Form 1-Aug Volume 131 Issue 3 Start Page 214 Other Pages 221 Notes LR: 20150426; CI: Copyright (c) 2013; GR: F32CA141933/CA/NCI NIH HHS/United States; GR: K01 DA027097/DA/NIDA NIH HHS/United States; GR: K01DA027097/DA/NIDA NIH HHS/United States; GR: P30 CA012197/CA/NCI NIH HHS/United States; GR: R01 AA014007/AA/NIAAA NIH Place of Publication Ireland ISSN/ISBN 1879-0046; 0376-8716 Accession Number PMID: 23746429 Language eng SubFile Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM DOI 10.1016/j.drugalcdep.2013.05.001 [doi] Output Language Unknown(0) PMID 23746429 Abstract BACKGROUND: Electronic cigarettes, or e-cigarettes, are battery operated devices that deliver nicotine via inhaled vapor. There is considerable controversy about the disease risk and toxicity of e-cigarettes and empirical evidence on short- and long-term health effects is minimal. Limited data on e-cigarette use and correlates exist, and to our knowledge, no prevalence rates among U.S. college students have been reported. This study aimed to estimate the prevalence of e-cigarette use and identify correlates of use among a large, multi-institution, random sample of college students. METHODS: 4444 students from 8 colleges in North Carolina completed a Web-based survey in fall 2009. RESULTS: Ever use of e-cigarettes was reported by 4.9% of students, with 1.5% reporting past month use. Correlates of ever use included male gender, Hispanic or "Other race" (compared to non-Hispanic Whites), Greek affiliation, conventional cigarette smoking and e-cigarette harm perceptions. Although e-cigarette use was more common among conventional cigarette smokers, 12% of ever e-cigarette users had never smoked a conventional cigarette. Among current cigarette smokers, e-cigarette use was negatively associated with lack of knowledge about e-cigarette harm, but was not associated with intentions to quit. CONCLUSIONS: Although e-cigarette use was more common among conventional cigarette smokers, it was not exclusive to them. E-cigarette use was not associated with intentions to quit smoking among a sub-sample of conventional cigarette smokers. Unlike older, more established cigarette smokers, e-cigarette use by college students does not appear to be motivated by the desire to quit cigarette smoking. Descriptors Links Book Title Database Publisher Elsevier Ireland Ltd Data Source Authors Sutfin,E.L., McCoy,T.P., Morrell,H.E., Hoeppner,B.B., Wolfson,M. Original/Translated Title URL Date of Electronic 20130607 PMCID PMC3760168 Editors
Identification of lactic acid bacteria in salted Chinese cabbage by SDS-PAGE and PCR-DGGE	2014	Department of Food Science and Biotechnology, and Institute of Life Sciences and Resources, Kyung Hee University, Yongin, 446-701, Korea.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of the science of food and agriculture Periodical, Abbrev. J.Sci.Food Agric. Pub Date Free Form 30-Jan Volume 94 Issue 2 Start Page 296 Other Pages 300 Notes CI: (c) 2013; JID: 0376334; 0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S); OTO: NOTNLM; 2013/04/01 [received]; 2013/05/20 [revised]; 2013/06/08 [accepted]; 2013/07/17 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1097-0010; 0022-5142 Accession Number PMID: 23749756 Language eng SubFile Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1002/jsfa.6257 [doi] Output Language Unknown(0) PMID 23749756 Abstract BACKGROUND: Lactic acid bacteria (LAB) in salted Chinese cabbage, the main ingredient of kimchi, were analyzed by culture-dependent sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), followed by sequencing of the 16S rRNA gene and by culture-independent polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE), followed by sequencing of the V3 region of the 16S rRNA gene. The results were compared to those of LAB that had previously been found in kimchi. RESULTS: The two identification methods produced distinct overall LAB profiles. The PCR-DGGE method detected a more diverse microflora, including non-LAB strains. The culture-dependent method uniquely detected Weissella sp. and was able to provide the quantitative distribution of LAB in samples. However, Leuconostoc mesenteroides, Lactobacillus curvatus and Leuconostoc carnosum, which had also been reported as the dominant LAB in kimchi in previous studies, were identified by both methods. CONCLUSION: The two identification methods gave different bacterial profiles, while both methods were sufficient to identify the most prevalent LAB in salted Chinese cabbage samples. The quantitative feature of the culture-dependent identification method would make it preferable for studying and monitoring LAB viability in kimchi at each fermentation stage. The availability of the culture-independent identification method to identify a broader bacterial profile, including non-LAB, would make it a more effective tool for controlling contamination of undesirable bacteria during kimchi fermentation. Descriptors Links Book Title Database Publisher Society of Chemical Industry Data Source Authors Hong,Y., Yang,H.S., Li,J., Han,S.K., Chang,H.C., Kim,H.Y. Original/Translated Title URL Date of Electronic 20130717 PMCID Editors
A cross-sectional analysis of the prevalence of Barrett esophagus in otolaryngology patients with laryngeal symptoms	2013	*Department of Cardiothoracic Surgery, Division of Thoracic and Foregut Surgery, University of Pittsburgh section signDepartment of Surgery, Western Pennsylvania Hospital, West Penn Allegheny Health System, Pittsburgh, PA Departments of daggerOtolaryngolo	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of clinical gastroenterology Periodical, Abbrev. J.Clin.Gastroenterol. Pub Date Free Form Oct Volume 47 Issue 9 Start Page 762 Other Pages 768 Notes LR: 20150426; GR: K07 CA151613/CA/NCI NIH HHS/United States; GR: K23 DK066165/DK/NIDDK NIH HHS/United States; GR: K23 DK066165-01/DK/NIDDK NIH HHS/United States; GR: R21 DK081161-01/DK/NIDDK NIH HHS/United States; GR: U01 DK57132/DK/NIDDK NIH HHS/United S Place of Publication United States ISSN/ISBN 1539-2031; 0192-0790 Accession Number PMID: 23751847 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1097/MCG.0b013e318293d522 [doi] Output Language Unknown(0) PMID 23751847 Abstract BACKGROUND: Populations at risk for esophageal adenocarcinoma remain poorly defined. Laryngeal symptoms can be secondary to laryngopharyngeal reflux (LPR) and can occur without associated gastroesophageal reflux symptoms such as heartburn and regurgitation. GOAL: We sought to determine the prevalence of Barrett esophagus (BE) in otolaryngology patients with laryngeal symptoms+/-typical gastroesophageal reflux disease (GERD) symptoms. STUDY: We performed a cross-sectional study of otolaryngology clinic patients who reported laryngeal symptoms. Symptoms, medications, and exposure histories were obtained. Unsedated transnasal endoscopy was performed. Suspected BE was biopsied and confirmed histologically. Risk factors and prevalence of BE were assessed. RESULTS: Two hundred ninety-five patients were enrolled [73% male, median age 60 y (interquartile range 51 to 68 y)]. The overall prevalence of BE was 11.8% (n=33). Antisecretory medication use was present in 56% (n=156) of patients at enrollment. Compared with patients without BE, patients with BE were more likely to be male (P=0.01) and to report occupational lung injury (P=0.001). Duration, but not severity of laryngeal symptoms, significantly increased the odds of BE (odds ratio, 5.64; 95% confidence interval, 1.28-24.83; for a duration of symptoms >5 y). Of patients with BE, 58% (n=19) had coexisting LPR and GERD symptoms and 30% (n=10) had only LPR symptoms. Presence and size of hiatal hernia and length of columnar-lined esophagus were significant risk factors for BE. CONCLUSIONS: Long-standing laryngeal symptoms are associated with the presence of BE in otolaryngology patients. Patients with chronic laryngeal symptoms and no identifiable ear, nose, or throat etiology for those symptoms may benefit from endoscopic screening regardless of whether typical GERD symptoms are present. Descriptors Links Book Title Database Publisher Data Source Authors Nason,K.S., Murphy,T., Schindler,J., Schipper,P.H., Hoppo,T., Diggs,B.S., Sauer,D.A., Shaheen,N.J., Morris,C.D., Jobe,B.A., Barrett's Esophagus Risk Consortium (BERC) Original/Translated Title URL Date of Electronic PMCID PMC4169870 Editors
Shear bond strength of resin cement to an acid etched and a laser irradiated ceramic surface	2013	Department of Prosthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, Turkey.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The journal of advanced prosthodontics Periodical, Abbrev. J.Adv.Prosthodont. Pub Date Free Form May Volume 5 Issue 2 Start Page 98 Other Pages 103 Notes LR: 20130613; JID: 101521064; OID: NLM: PMC3675300; OTO: NOTNLM; 2012/10/02 [received]; 2013/02/14 [revised]; 2013/04/25 [accepted]; 2013/05/30 [epublish]; ppublish Place of Publication Korea (South) ISSN/ISBN 2005-7806; 2005-7806 Accession Number PMID: 23755333 Language eng SubFile Journal Article DOI 10.4047/jap.2013.5.2.98 [doi] Output Language Unknown(0) PMID 23755333 Abstract PURPOSE: To evaluate the effects of hydrofluoric acid etching and Er,Cr:YSGG laser irradiation on the shear bond strength of resin cement to lithium disilicate ceramic. MATERIALS AND METHODS: Fifty-five ceramic blocks (5 mm x 5 mm x 2 mm) were fabricated and embedded in acrylic resin. Their surfaces were finished with 1000-grit silicon carbide paper. The blocks were assigned to five groups: 1) 9.5% hydrofluoric-acid etching for 60 s; 2-4), 1.5-, 2.5-, and 6-W Er,Cr:YSGG laser applications for 60 seconds, respectively; and 5) no treatment (control). One specimen from each group was examined using scanning electron microscopy. Ceramic primer (Rely X ceramic primer) and adhesive (Adper Single Bond) were applied to the ceramic surfaces, followed by resin cement to bond the composite cylinders, and light curing. Bonded specimens were stored in distilled water at 37 for 24 hours. Shear bond strengths were determined by a universal testing machine at 1 mm/min crosshead speed. Data were analyzed using Kruskal-Wallis and Mann-Whitney U-tests (alpha=0.05). RESULTS: Adhesion was significantly stronger in Group 2 (3.88 +/- 1.94 MPa) and Group 3 (3.65 +/- 1.87 MPa) than in Control group (1.95 +/- 1.06 MPa), in which bonding values were lowest (P<.01 no="" significant="" difference="" was="" observed="" between="" group="" mpa="" and="" control="" group.="" shear="" bond="" strength="" highest="" in="" p="" conclusion:="" er="" laser="" irradiation="" at="" w="" increased="" strengths="" ceramic="" resin="" cement="" compared="" with="" untreated="" surfaces.="" may="" not="" be="" an="" efficient="" surface="" treatment="" technique.=""> Descriptors Links Book Title Database Publisher Data Source Authors Kursoglu,P., Motro,P.F., Yurdaguven,H. Original/Translated Title URL Date of Electronic 20130530 PMCID PMC3675300 Editors

E-mail