Skip to main content
Title Pub Year Author SearchLink Sort descending
Smoking prevalence in Italy 2011 and 2012, with a focus on hand-rolled cigarettes 2013 Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri-IRCCS, Milan, Italy. silvano.gallus@marionegri.it
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Preventive medicine
Periodical, Abbrev.
Prev.Med.
Pub Date Free Form
May
Volume
56
Issue
5
Start Page
314
Other Pages
318
Notes
CI: Copyright (c) 2013; JID: 0322116; 2012/09/28 [received]; 2013/01/07 [revised]; 2013/02/13 [accepted]; 2013/02/24 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1096-0260; 0091-7435
Accession Number
PMID: 23462480
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.ypmed.2013.02.009 [doi]
Output Language
Unknown(0)
PMID
23462480
Abstract
OBJECTIVE: To provide updated information on smoking prevalence in Italy, with a focus on type of tobacco product, including hand-rolled (HR) cigarettes. METHOD: Two nationally representative surveys were conducted in 2011 and 2012 in Italy on a total sample of 6167 adults. Information on type of tobacco most frequently smoked was collected. RESULTS: Current smokers were 21.7% (22.7% in 2011 and 20.8% in 2012) overall, 25.3% among men and 18.4% among women. Among smokers, 94.6% most frequently consumed manufactured cigarettes, 4.6% HR cigarettes, 0.5% cigars, 0.2% cigarillos, and 0.2% pipe and none smokeless tobacco. HR cigarette use was more frequent in men (6.9%) than in women (1.7%), in 2012 (5.9%) than in 2011 (3.4%), and among the young (15-24 years; 9.1%). The average estimated price of one HR cigarette was 0.09euro and that of a manufactured cigarette was 0.18euro. CONCLUSION: In 2012 we observed the lowest reported overall smoking prevalence in Italy, though change since 2008 has been limited. The proportion of HR cigarettes on total tobacco trade has appreciably increased, particularly among young male smokers, who appear to switch to affordable cigarettes in a period of economic crisis. Fiscal policies aiming to equalise the cost of different cigarette types are needed in Italy.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Inc
Data Source
Authors
Gallus,S., Lugo,A., Colombo,P., Pacifici,R., La Vecchia,C.
Original/Translated Title
URL
Date of Electronic
20130224
PMCID
Editors
Comparison of nicotine and carcinogen exposure with water pipe and cigarette smoking 2013 Division of Clinical Pharmacology, University of California, San Francisco, San Francisco General Hospital, Building 100, Room 235, San Francisco, CA 94110, USA. peyton.jacob@ucsf.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Periodical, Abbrev.
Cancer Epidemiol.Biomarkers Prev.
Pub Date Free Form
May
Volume
22
Issue
5
Start Page
765
Other Pages
772
Notes
LR: 20160408; GR: DA012393/DA/NIDA NIH HHS/United States; GR: P30 DA012393/DA/NIDA NIH HHS/United States; GR: UL1 RR024131/RR/NCRR NIH HHS/United States; JID: 9200608; 0 (Biomarkers); 0 (Carcinogens); 6M3C89ZY6R (Nicotine); NIHMS451482; OID: NLM: NIHMS451
Place of Publication
United States
ISSN/ISBN
1538-7755; 1055-9965
Accession Number
PMID: 23462922
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1158/1055-9965.EPI-12-1422 [doi]
Output Language
Unknown(0)
PMID
23462922
Abstract
BACKGROUND: Smoking tobacco preparations in a water pipe (hookah) is widespread in many places of the world and is perceived by many as relatively safe. We investigated biomarkers of toxicant exposure with water pipe compared with cigarette smoking. METHODS: We conducted a crossover study to assess daily nicotine and carcinogen exposure with water pipe and cigarette smoking in 13 people who were experienced in using both products. RESULTS: When smoking an average of 3 water pipe sessions compared with smoking 11 cigarettes per day (cpd), water pipe use was associated with a significantly lower intake of nicotine, greater exposure to carbon monoxide (CO), and a different pattern of carcinogen exposure compared with cigarette smoking, with greater exposure to benzene, and high molecular weight polycyclic aromatic hydrocarbon (PAH), but less exposure to tobacco-specific nitrosamines, 1,3-butadiene, acrolein, acrylonitrile, propylene oxide, ethylene oxide, and low molecular weight PAHs. CONCLUSIONS: A different pattern of carcinogen exposure might result in a different cancer risk profile between cigarette and water pipe smoking. Of particular concern is the risk of leukemia related to high levels of benzene exposure with water pipe use. IMPACT: Smoking tobacco in water pipes has gained popularity in the United States and around the world. Many believe that water pipe smoking is not addictive and less harmful than cigarette smoking. We provide data on toxicant exposure that will help guide regulation and public education regarding water pipe health risk.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Jacob,P.,3rd, Abu Raddaha,A.H., Dempsey,D., Havel,C., Peng,M., Yu,L., Benowitz,N.L.
Original/Translated Title
URL
Date of Electronic
20130305
PMCID
PMC3650103
Editors
Barrett's esophagus and beta-carotene therapy: symptomatic improvement in GERD and enhanced HSP70 expression in esophageal mucosa 2012 Department of Medicine, University of Maryland School of Medicine and Division Director of Gastroenterology, USA. sdutta@lifebridgehealth.org
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Asian Pacific journal of cancer prevention : APJCP
Periodical, Abbrev.
Asian Pac.J.Cancer.Prev.
Pub Date Free Form
Volume
13
Issue
12
Start Page
6011
Other Pages
6016
Notes
JID: 101130625; 0 (HSP70 Heat-Shock Proteins); 01YAE03M7J (beta Carotene); ppublish
Place of Publication
Thailand
ISSN/ISBN
1513-7368; 1513-7368
Accession Number
PMID: 23464395
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
23464395
Abstract
INTRODUCTION: Epidemiological studies suggest a protective role for beta-carotene with several malignancies. Esophageal adenocarcinoma frequently arises from Barrett's esophagus (BE). We postulated that beta-carotene therapy maybe protective in BE. MATERIALS AND METHOD: We conducted a prospective study in which 25 mg of beta-carotene was administered daily for six-months to six patients. Each patient underwent upper endoscopy before and after therapy and multiple mucosal biopsies were obtained. Additionally, patients completed a gastroesophageal reflux disease (GERD) symptoms questionnaire before and after therapy and severity score was calculated. To study the effect of beta-carotene at molecular level, tissue extracts of the esophageal mucosal biopsy were subjected to assessment of heat-shock protein 70 (HSP70). RESULTS: A significant (p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Dutta,S.K., Agrawal,K., Girotra,M., Fleisher,A.S., Motevalli,M., Mah'moud,M.A., Nair,P.P.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Comparison of air-agitated liquid-liquid microextraction technique and conventional dispersive liquid-liquid micro-extraction for determination of triazole pesticides in aqueous samples by gas chromatography with flame ionization detection 2013 Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran. mafarajzadeh@yahoo.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
26-Jul
Volume
1300
Issue
Start Page
70
Other Pages
78
Notes
LR: 20151119; CI: Copyright (c) 2013; JID: 9318488; 0 (Pesticide Residues); 0 (Triazoles); 1N41638RNO (Ethylene Dibromide); 451W47IQ8X (Sodium Chloride); Y4S76JWI15 (Methanol); OTO: NOTNLM; 2012/11/28 [received]; 2013/02/11 [revised]; 2013/02/12 [accepted
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 23473511
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.chroma.2013.02.033 [doi]
Output Language
Unknown(0)
PMID
23473511
Abstract
Two micro-extraction methods, air-agitated liquid-liquid microextraction (AALLME) and dispersive liquid-liquid microextraction (DLLME), have been compared with each other by applying them for the analysis of five triazole pesticides (penconazole, hexaconazole, diniconazole, tebuconazole and triticonazole) in aqueous samples by gas chromatography with flame ionization detection (GC-FID). In the AALLME method, which excludes any disperser solvent, much less volume of organic solvent is used. In order to form fine and dispersed organic droplets in the aqueous phase, the mixture of aqueous sample solution and extraction solvent is repeatedly aspirated and dispensed with a syringe. In the DLLME method, an appropriate mixture of extraction solvent and disperser solvent is rapidly injected by a syringe into the aqueous sample. Effect of the pertinent experimental factors on DLLME (i.e. identity and volume of the extraction and disperser solvents and ionic strength) and on AALLME (identity and volume of the extraction solvent, number of agitations, and ionic strength) were investigated. Under optimal conditions, limits of detection for the five target pesticides obtained by AALLME-GC-FID and DLLME-GC-FID ranged from 0.20 to 1.1ngmL(-1) and 1.9 to 5.9ngmL(-1), respectively. The relative standard deviations (RSDs, n=5) were in the range of 1-4% and 3-5% with the enrichment factors of 449-504 and 79-143 for AALLME-GC-FID and DLLME-GC-FID, respectively. Both of the compared methods are simple, fast, efficient, inexpensive and can be applied to the analysis of the five pesticides in different aqueous samples in which penconazole and hexaconazole were found. For spiked samples, the recoveries were in the ranges of 92-105%, and 92-104% for AALLME and DLLME, respectively.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Farajzadeh,M.A., Mogaddam,M.R., Aghdam,A.A.
Original/Translated Title
URL
Date of Electronic
20130219
PMCID
Editors
Prognostic and predictive biomarkers in gastroenteropancreatic neuroendocrine tumors 2013 Tufts University School of Medicine, Boston, MA, USA. rstevenson@tuftsmedicalcenter.org
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
JOP : Journal of the pancreas
Periodical, Abbrev.
JOP
Pub Date Free Form
10-Mar
Volume
14
Issue
2
Start Page
155
Other Pages
157
Notes
LR: 20151119; JID: 101091810; 0 (Antineoplastic Agents); 0 (Biomarkers, Pharmacological); 0 (Biomarkers, Tumor); 9HW64Q8G6G (Everolimus); EC 3.1.3.16 (PHLPP2 protein, human); EC 3.1.3.16 (Phosphoprotein Phosphatases); W36ZG6FT64 (Sirolimus); 2013/02/12 [r
Place of Publication
Italy
ISSN/ISBN
1590-8577; 1590-8577
Accession Number
PMID: 23474561
Language
eng
SubFile
Journal Article; Review; IM
DOI
10.6092/1590-8577/1472 [doi]
Output Language
Unknown(0)
PMID
23474561
Abstract
Neuroendocrine tumors (NET) are a diverse group of tumors that derive from epithelial cells with neuroendocrine differentiation. Gastroenteropancreatic NETs are a subset of NET that arise from the gastrointestinal tract. The natural history and prognosis varies widely between different gastroenteropancreatic NETs, highlighting the importance of identifying accurate prognostic and predictive biomarkers. At the 2013 ASCO Gastrointestinal Cancers Symposium, De Braud et al. (Abstract #186) and Bellister et al. (Abstract #163) present data on two new possible biomarkers.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Stevenson,R., Libutti,S.K., Saif,M.W.
Original/Translated Title
URL
Date of Electronic
20130310
PMCID
Editors
1-(2-Amino-6-methyl-pyrimidin-4-yl)-N,N-dimethyl-piperidin-4-aminium chloride 2012 Department of Studies and Research in Chemistry, Tumkur University, Tumkur, Karnataka 572 103, India.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
1-Dec
Volume
68
Issue
Pt 12
Start Page
o3371
Other Pages
Notes
LR: 20130418; JID: 101089178; OID: NLM: PMC3588967; 2012/11/10 [received]; 2012/11/11 [accepted]; 2012/11/17 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 23476203
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536812046533 [doi]
Output Language
Unknown(0)
PMID
23476203
Abstract
In the title mol-ecular salt, C12H22N5(+).Cl(-), the cation is protonated at the dimethyl-substituted tertiary N atom. The piperidine ring adopts a chair conformation with the exocyclic N-C bond in an equatorial orientation. The dihedral angle between the piperidine ring (all atoms) and the pyrimidine ring is 14.00 (1) degrees . In the crystal, the ions are connected by N-Hcdots, three dots, centeredN hydrogen bonds, forming inversion dimers, which are further connected by N-Hcdots, three dots, centeredCl hydrogen bonds. Aromatic pi-pi stacking inter-actions [centroid-centroid separation = 3.4790 (9) A] are also observed in the structure.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Sreenivasa,S., Manojkumar,K.E., Suchetan,P.A., Srinivasan,T., Palakshamurthy,B.S., Velmurgan,D.
Original/Translated Title
URL
Date of Electronic
20121117
PMCID
PMC3588967
Editors
N-(4-Fluoro-benzo-yl)-N',N''-diisopropyl-phospho-ric triamide 2012 Department of Chemistry, Ferdowsi University of Mashhad, Mashhad, Iran.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
1-Dec
Volume
68
Issue
Pt 12
Start Page
o3406
Other Pages
7
Notes
LR: 20130418; JID: 101089178; OID: NLM: PMC3588995; 2012/11/06 [received]; 2012/11/09 [accepted]; 2012/11/24 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 23476231
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536812046326 [doi]
Output Language
Unknown(0)
PMID
23476231
Abstract
The asymmetric unit of the title phospho-ric triamide, C13H21FN3O2P, consists of two independent mol-ecules. In each mol-ecule, the P=O group and the N-H unit belonging to the C(O)NHP(O) fragment are in a syn conformation with respect to each other. An intra-molecular N-Hcdots, three dots, centeredO hydrogen bond occurs in each mol-ecule. The P atom adopts a distorted tetra-hedral environment. The methyl groups of an isopropyl fragment are disordered over two sets of sites with refined occupancies of 0.458 (5) and 0.542 (5). In the crystal, mol-ecules are linked through N-Hcdots, three dots, centeredO(=P) and N-Hcdots, three dots, centeredO(=C) hydrogen bonds into chains along [001].
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Pourayoubi,M., Tarahhomi,A., Rheingold,A.L., Golen,J.A.
Original/Translated Title
URL
Date of Electronic
20121124
PMCID
PMC3588995
Editors
N-[3a-(4-Bromo-phen-yl)-8b-hy-droxy-6,8-dimeth-oxy-3-phenyl-2,3,3a,8b-tetra-hydro -1H-cyclo-penta-[b]benzofuran-1-yl]formamide monohydrate 2013 Cristallographie, Resonance Magnetique et Modelisations (CRM2), UMR CNRS-UHP 7036, Institut Jean Barriol, Universite de Lorraine, BP 70239, Bd des Aiguillettes, 54506 Vandoeuvre-les-Nancy, France.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
1-Jan
Volume
69
Issue
Pt 1
Start Page
o52
Other Pages
3
Notes
LR: 20130418; JID: 101089178; OID: NLM: PMC3588239; 2012/11/22 [received]; 2012/12/03 [accepted]; 2012/12/08 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 23476436
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536812049641 [doi]
Output Language
Unknown(0)
PMID
23476436
Abstract
In the title compound, C26H24BrNO5.H2O, a synthetic analogue of natural flavagline, the cyclo-pentane ring adopts an envelope conformation (the flap atom bearing the phenyl group) and the vicinal phenyl and bromo-phenyl groups are slightly shifted relative to each other [CPh-C-C-CPhBr = 36.3 (2) degrees ]. Intra-molecular N-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredO hydrogen bonds form S(5) motifs. In the crystal, the organic and the water mol-ecules are linked by an O-Hcdots, three dots, centeredO hydrogen bond. Pairs of organic and water mol-ecules, located about inversion centers, inter-act through O-Hcdots, three dots, centeredO hydrogen bonds, forming R4(4)(20) and R4(4)(26) motifs, which together lead to C2(2)(9) motifs. The crystal packing is also characterized by N-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredO hydrogen bonds between neighbouring organic mol-ecules, forming R2(2)(10) and R2(2)(18) motifs, respectively.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Aubert,E., Thuaud,F., Ribeiro,N., Desaubry,L., Espinosa,E.
Original/Translated Title
URL
Date of Electronic
20121208
PMCID
PMC3588239
Editors
(Z)-N-[2-(N'-Hy-droxy-carbamimido-yl)phen-yl]acetamide 2013 X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia ; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, PO Box 2457, Riyadh 11451, Saudi Arabia.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
1-Mar
Volume
69
Issue
Pt 3
Start Page
o370
Other Pages
1
Notes
LR: 20130418; JID: 101089178; OID: NLM: PMC3588555; 2013/02/02 [received]; 2013/02/02 [accepted]; 2013/02/09 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 23476559
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536813003371 [doi]
Output Language
Unknown(0)
PMID
23476559
Abstract
The asymmetric unit of the title compound, C9H11N3O2, contains two mol-ecules (A and B), which exist in Z conformations with respect to their C=N double bond. The dihedral angles between the benzene ring and the pendant hy-droxy-carbamimidoyl and acetamide groups are 28.58 (7) and 1.30 (5) degrees , respectively, in mol-ecule A and 25.04 (7) and 27.85 (9) degrees , respectively, in mol-ecule B. An intra-molecular N-Hcdots, three dots, centeredN hydrogen bond generates an S(6) ring in both mol-ecules. Mol-ecule A also features an intra-molecular C-Hcdots, three dots, centeredO inter-action, which closes an S(6) ring. In the crystal, the mol-ecules are linked by N-Hcdots, three dots, centeredO, N-Hcdots, three dots, centeredN, O-Hcdots, three dots, centeredO, O-Hcdots, three dots, centeredN, C-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredN hydrogen bonds and C-Hcdots, three dots, centeredpi inter-actions, generating a three-dimensional network.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Fun,H.K., Ooi,C.W., Dinesha, Viveka,S., Nagaraja,G.K.
Original/Translated Title
URL
Date of Electronic
20130209
PMCID
PMC3588555
Editors
Alternative tobacco product use and smoking cessation: a national study 2013 Center for Tobacco Control Research and Education, University of California, San Francisco, CA 94143-1390, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Public Health
Periodical, Abbrev.
Am.J.Public Health
Pub Date Free Form
May
Volume
103
Issue
5
Start Page
923
Other Pages
930
Notes
LR: 20151119; GR: R01 CA141661/CA/NCI NIH HHS/United States; GR: R01-CA141661/CA/NCI NIH HHS/United States; JID: 1254074; 0 (Nicotinic Agonists); 6M3C89ZY6R (Nicotine); NIHMS456593; OID: NLM: NIHMS456593; OID: NLM: PMC3661190; 2013/03/14 [aheadofprint]; p
Place of Publication
United States
ISSN/ISBN
1541-0048; 0090-0036
Accession Number
PMID: 23488521
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; AIM; IM
DOI
10.2105/AJPH.2012.301070 [doi]
Output Language
Unknown(0)
PMID
23488521
Abstract
OBJECTIVES: We investigated the frequency of alternative tobacco product use (loose leaf, moist snuff, snus, dissolvables, electronic cigarettes [e-cigarettes]) among smokers and the association with quit attempts and intentions. METHODS: A nationally representative probability-based cross-sectional survey of 1836 current or recently former adult smokers was completed in November 2011. Multivariate logistic regressions evaluated associations between alternative tobacco product use and smoking cessation behaviors. RESULTS: Of the smokers, 38% had tried an alternative tobacco product, most frequently e-cigarettes. Alternative tobacco product use was associated with having made a quit attempt, and those intending to quit were significantly more likely to have tried and to currently use the products than were smokers with no intentions to quit. Use was not associated with successful quit attempts. Interest in future use of alternative tobacco products was low, except for e-cigarettes. CONCLUSIONS: Alternative tobacco products are attractive to smokers who want to quit smoking, but these data did not indicate that alternative tobacco products promote cessation. Unsubstantiated overt and implied claims that alternative tobacco products aid smoking cessation should be prohibited.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Popova,L., Ling,P.M.
Original/Translated Title
URL
Date of Electronic
20130314
PMCID
PMC3661190
Editors